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Quick Search     Adv Search 2018 Vol. 25, No. 10 Published: 2018-04-08   4 Influence of addition of different molar concentration of DHA into Glycerol-Egg Yolk-Citrate Cryopreservative Mediums on the kinematic parameters of human sperm before and after cryosurgery MA Chun-jie;ZHUANG Jia-ming;DENG Shun-mei;TANG Yun-ge; QIN Wei-bing; WANG Qi-ling;ZHANG Xin-zong Objective To study the influence of addition of different molar concentration of docosahexaenoic acid(DHA)into Glycerol-Egg Yolk-Citrate(GEYC)cryopreservative mediums on the kinematic parameters of human sperm before and after cryosurgery so as to explore the application value of n-3 polyunsaturated fatty acids in cryosurgery of human sperm.Methods Altogether 33 cases of semen samples which came from semen donors during human sperm bank screening period in Guangzhou Family Planning Specialty Hospital from March 2016 to April 2017 were selected.Based on GEYC cryopreservative mediums,the concentration of exogenous DHA in mixed semen-GEYC liquor were 0 mmol/L in the control group,0.317 mmol/L in the DHA 1 group,0.634 mmol/L in the DHA 2 group and 1.268 mmol/L in the DHA 3 group.SCA 5.2 computer-assisted sperm analysis system was used to detect the sperm kinematics parameters 0-8 hours after addition of cryopreservation and frozen resuscitation.Results After addition of cryopreservation and frozen resuscitation,only curve line velocity(VCL)and average path velocity(VAP)of the DHA 3 group were significantly lower than those of the control group (P＜0.05),there was no statistically significant difference in kinematic parameters between the other groups(P＞0.05).After frozen recovery at 0,4,5,6,8 hours,only kinematic parameters of the DHA 3 group decreased occasionally,with statistically significant difference in contrast with 3 groups.After cryosurgery at 0-8 hours,most of the kinematic parameters had no statistically significant difference between each group(P＞0.05).Conclusion Addition of DHA into GEYC cryo-preservative mediums do not increase the sperm kinematic parameters before and after cryosurgery.The proper addition of DHA may affect frozen semen through other ways.Addition of a large number of DHA may have a negative impact on the part of the kinematic parameters before and after cryosurgery. 2018 Vol. 25 (10): 4-8 [Abstract] ( 187 ) HTML (37 KB)  PDF  (0 KB)  ( 32 ) 9 Analysis of the relationship between expression of myeloid-derived suppressor cell and liver failure after transcatheter arterial chemoembolization ZHANG Wei;SHAO Ming-liang;LIU Wen-zong;ZHANG Hai-cong;YAN Hui-min; ZHENG Huan-wei Objective To investigate the relationship between the occurrence of hepatic failure after transcatheter arterial chemoembolization(TACE)and the expression of myeloid-derived suppressor cell(MDSC).Methods Altogether 237 patients with HBV-related primary liver cancer(PLC)who were hospitalized in our hospital from May 2011 to January 2015 were selected as the subject of this research,according to the the occurrence of liver failure,all patients were divided into 105 cases in liver failure group and 132 cases in non-liver failure group.The difference of MDSC expressions after TACE was analyzed.According to the degree of liver failure,all the patients were divided into mild liver failure group(47 cases),moderate group(31 cases),severe group(27 cases),according to the prognosis of liver failure,all the patients were divided into death group(10 cases)and improvement group(95 cases).The difference of MDSC expressions in each group was compared.Results The MDSC-m phenotype of the PLC patients in liver failure group was significantly higher than that in the non-liver failure group,with significant difference(P=0.0405).MDSC-m of severe liver failure group was significantly higher than that of mild group,with significant difference between the two groups(P＜0.001).MDSC-m level of the liver failure death group was significantly higher than that of improvement group,with significant difference between the two groups(P＜0.01).Conclusion The occurrence and prognosis of hepatic failure after TACE is closely related to the high expression of MDSC. 2018 Vol. 25 (10): 9-12 [Abstract] ( 194 ) HTML (32 KB)  PDF  (0 KB)  ( 31 ) 13 Research on the survival status of patients with hepatocellular carcinoma after radical surgical treatment YUAN Bo;LIAO Jin-qi;FANG Yong-ping Objective To explore the survival status of patients with hepatocellular carcinoma after radical surgery in order to analyze the prognostic factors and provide direction and basis for clinical treatment of hepatocellular carcinoma.Methods The clinical data of 146 patients with hepatocellular carcinoma undergone surgical treatment from June 2008 to June 2012 in the central hospital(because these surgeons still worked in the Central Hospital of Huizhou)were retrospectively analyzed.All cases were followed up for 5 years after operation.All related factors were analyzed by single factor analysis,after that the Cox regression multiple-factor analysis was carried out if the index was statistically significant after single factor analysis.Results All the participants were successfully performed.Eighty cases were performed with anatomical hepatectomy,and the rest cases were not.Postoperative complications occurred in 10 patients,including pleural effusion(4 cases),incisional infection(2 cases),postoperative fever(2 cases),and intestinal obstruction(2 cases).A-mong them,some patients had multiple complications.After 5-year follow-up,the follow-up was from 1 to 139 months,and the median survival time was 59 months.The total survival rate of 5 years was 47.95% (70/146),and 3 cases were lost accounting for 2.05%.Univariate analysis showed that gender,age,grade of liver function,hepatic portal occlusion,and surgical mode were not related factors influencing on the survival state of patients with hepatocellular carcinoma after radical surgery therapy(P＞0.05).The related factors were tumor capsule,aspartate aminotransferase,microvascular invasion,tumor size,amount of tumor,tumor differentiation,total cholesterol,and AJCC stage(P＜0.05).Multivariate regression analysis displayed that tumor differentiation,microvascular invasion,tumor size,tumor number,and AJCC stage were independent factors that affected the survival status of patients with hepatocellular carcinoma after radical surgery(P＜0.05).Conclusion Both anatomical liver resection and non-anatomical liver resection for the treatment of patients with hepatocellular carcinoma have better long-term effects.Tumor differentiation,microvascular invasion,tumor size,number of tumor,and AJCC stage are independent factors influencing on the survival status of patients with hepatocellular carcinoma after radical surgery. 2018 Vol. 25 (10): 13-15 [Abstract] ( 189 ) HTML (28 KB)  PDF  (0 KB)  ( 31 ) 16 Comparison of the effect of Palonosetron and Tropisetron in the prevention of nausea and vomiting after single segment lumbar decompression,bone graft fusion and internal fixation LIANG Jun-li;LYU Wen-yan Objective To investigate the effect of single injection of Palonosetron and Tropisetron in the prevention of nausea and vomiting(PONV)after single-segment lumbar decompression,bone graft fusion and internal fixation.Methods A total of 70 patients of 117thHospital of PLA from February to July in 2017 underwent single segment posterior lumbar interbody fusion surgery,ASA score ofⅠorⅡgrade,Apfel score more than 3 points,and the patients who unwent elective lumbar posterior decompression and internal fixation surgery were selected as the research object.According to the random single blind,70 patients were divided into the palonosetron group(group P)and the tropisetron group(group T),35 cases in each group.Anesthesia with intravenous inhalational anesthesia,skin suture,group P was given intravenous Palonosetron 0.25 mg,group T was given Tropisetron or 5 mg,and were treated with Sufentanil 50 μg+Dezocine 20 mg analgesia (PCIA),the follow-up of 72 h.The incidence of nausea and vomiting after operation in the two groups was compared and the total effective rate(CR)was calculated.Results The incidence of nausea in group P at 0-24 h and＞24-48 h after operation was 25.7%(9/35),8.6%(3/35),which was significantly lower than that of group T of 48.6%(17/35),28.6%(10/35);the incidence of vomiting in group P was 14.3%(5/35),5.7%(2/35),which was significantly lower than that of group T of 45.7%(16/35),25.7%(9/35),the differences were statistically significant(P＜0.05).The incidence of nausea and vomiting in the two groups at＞48-72 h after operation was no significant difference (P＞0.05).After 0-24 h,＞24-48 h and 0-72 h,the CR standard rates of group P were 85.7%,94.3%and 80.0%,which were significantly higher than those in group T(54.3%,77.1%and 54.0%),the differences were statistically significant(P＜0.05).The CR standard rates of 48-72 h in group P and group T were 100.0%and 97.1%,and the difference was not statistically significant(P＞0.05).Conclusion In the prevention of nausea and vomiting during the postoperative analgesia of the lumbar surgery,the effect of single-dose intravenous injection of Palonosetron of 0.25 mg at the end of the operation is superior to that of the single intravenous injection of Tropisetron 5 mg. 2018 Vol. 25 (10): 16-18转22 [Abstract] ( 174 ) HTML (30 KB)  PDF  (0 KB)  ( 26 ) 19 Influence of Liraglutide combined with Metformin in the treatment of polycystic ovary syndrome on the morbidity of gestational diabetes mellitus HU Xiao-na Objective To observe the influence of Liraglutide combined with Metformin treating polycystic ovary syndrome(PCOS)on the morbidity of gestational diabetes mellitus(GDM).Methods Sixty-pregnancy women diagnosed with PCOS who visited the Department of Endocrinology in our hospital from October 2014 to April 2017 were enrolled and divided into the experimental group(n=21)and the control group(n=39)based on whether Liraglutide was used or not before pregnancy.In the experimental group,participants were treated with Liraglutide combined with Metformin for more than 6 months before pregnancy and continued with Metformin after pregnancy.In the control group,oral administration of Metformin alone was adopted for these PCOS women,and did not continue Metformin treatment during pregnancy.All subjects were provided with oral glucose tolerance test(OGTT)during pregnancy.The incidence of GDM,cesarean section rate,premature birth rate and weight change were observed in the two groups.Results The weight loss rate of the experimental group before pregnancy was higher than that of the control group,with significant difference(P＜0.05).The incidence of GDM in the experimental group was lower than that in the control group,with significant difference(P＜0.05).The body weight of the experimental group at weeks 24,32,and 36 weeks of the pregnancy was lower than that of the control group,with significant difference(P＜0.05).Conclusion Liraglutide combined with Metformin can preventively reduce the morbidity of GDM in PCOS women. 2018 Vol. 25 (10): 19-22 [Abstract] ( 208 ) HTML (30 KB)  PDF  (0 KB)  ( 36 ) 23 Research progress of probiotics in prevention and treatment of respiratory tract infection ZOU Yang;XIAO Chun-ling Respiratory tract infection is a common respiratory disease with high incidence and mortality in the world and has become an important issue of global concern.Antibiotics are effective in treating respiratory infections,but large numbers and unreasonable use of antibiotics can cause imbalance of flora,which resulting in low immunity to the human body,especially in children and the elderly,recurrent infection is easy to appear.In this paper,In this paper,the regulation role of probiotics on respiratory flora is reviewed. 2018 Vol. 25 (10): 23-26 [Abstract] ( 176 ) HTML (37 KB)  PDF  (0 KB)  ( 33 ) 27 Effects and applications of Poloxamer 407 YIN Na;YANG Mao-sheng Poloxamer 407 is a thermo-sensitive polymer material with characteristics of unique properties of reverse thermo-gel,good sustained release role,hypotoxicity and high bioavailability and so on,and is used widely in the food and pharmaceutical industry.In this paper,the structure and physical or chemical properties,effects and mechanisms,applications and outlook of Poloxamer 407 and so on are overviewed to provide new evidence and ideas for the use or further research and development of poloxamer 407. 2018 Vol. 25 (10): 27-30 [Abstract] ( 226 ) HTML (34 KB)  PDF (1574 KB)  ( 40 ) 31 Endoscopic submucosal dissection in the treatment of laterally spreading tumors of large intestine CHEN Wei-chao;XIE Zhi-lian;XU Chun-xiang Objective To study and explore the clinical effect of endoscopic submucosal dissection in the treatment of laterally spreading tumor of large intestine.Methods From January 2015 to January 2017,50 patients with laterally spreading tumor of the large intestine treated in our hospital were selected as the subjects,according to the computer random grouping method,the patients were divided into two groups,25 cases in each group.The control group received endoscopic mucosal resection,the observation group received endoscopic submucosal dissection.The operation time,intraoperative bleeding,en bloc resection rate,complete resection rate surgical operation,probability,complication rate,recurrence rate were compared between the two groups.Results The operation time in the observation group was longer than that in the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the amount of bleeding between the observation group and the control group(P＞0.05).The overall resection rate and complete resection rate of the observation group were higher than those of the control group,the differences were statistically significant(P＜0.05).In the endoscopic treatment,the probability of surgery in the observation group was 8%,and the control group was 4%,there was no significant difference between the two groups(P＞0.05).After operation,the total incidence of complications in the observation group was 12%,and the control group was 4%,there was no significant difference between the two groups(P＞0.05).After a follow-up of 3 to 12 months,the local recurrence rate of the observation group was 4%,which was lower than that of the control group(24%)(P＜0.05).Conclusion Endoscopic submucosal dissection has a significant effect in the treatment of laterally spreading tumors of the colon,which not only has high en bloc resection rate,complete resection rate,but also can effectively reduce the local recurrence of tumor. 2018 Vol. 25 (10): 31-33转40 [Abstract] ( 179 ) HTML (30 KB)  PDF (1612 KB)  ( 29 ) 34 Effect of bile duodenogastric reflux on postoperative nausea and vomiting in laparoscopic cholecystectomy JIANG Fei;WU Ai-ling;YAN Yuan;HUANG Hui;ZHANG Fang-yu;ZHONG Xiao-ming Objective To explore the effect of bile duodenogastric reflux on postoperative nausea and vomiting(PONV)in laparoscopic cholecystectomy by using gastroscope.Methods From March 2015 to May 2017,90 patients undergo laparoscopic cholecystectomy treated in our hospital were selected as the subjects,and divided into group A(gastroscope group A),group B(gastroscope group B)and group C(control group)by radom table method,30 cases in each group.They were all underwent general anesthesia.Gastroscope was inserted at the time of tracheal intubation (T1)and extubation(T2)immediately in group A and group B,the insertion time was less than 2 min.Bile duodenogastric reflux was observed in the two groups and the extracted reflux was biochemical analysed.The bile was sufficiently sucked if reflux occurred in group B at T2.No Gastroscope was inserted in group C.The VAS score of nausea and vomiting was recorded 6 h(T3),12 h(T4),24 h(T5)postoperative,the incidence rate of severe nausea and vomiting(VAS＞4)was also recorded.Results At T1,no bile duodenogastric reflux observed by gastroscope in group A and group B.At T2,the incidence rate of bile duodenal reflux was 100%,the incidence rate of bile gastric reflux between group A(83.3%)and group B(86.7%)had no significant difference(P＞0.05).Biochemical analyses showed no significant difference between group A and group B.At T3and T4,the incidence rate of nausea and vomiting VAS score in group B ([2.90±1.30],[1.63±1.03]points)was lower than group A([5.90±1.58],[3.80±1.42]points)and group C([5.73±1.48],[3.60±1.30]points)(P＞0.05).The incidence rate of severe nausea and vomiting in group B (13.3%,6.7%)were lower than group A (83.3%,40.0%)and group C(80.0%,30.0%)(P＜0.05).The nausea and vomiting VAS score had no difference at T5(P＞0.05).Conclusion Laparoscopic Cholecystectomy(LC)can cause acute bile duodenogastric reflux,thus causing more postoperative nausea and vomiting. 2018 Vol. 25 (10): 34-37 [Abstract] ( 171 ) HTML (35 KB)  PDF (1819 KB)  ( 35 ) 38 Effect of psychological intervention on depression status and quality of life in patients with chronic obstructive pulmonary disease CAO Guang-lan;YANG Qiao-feng;LI Ai-qin Objective To analyze the effect of psychological intervention on the improvement of anxiety and depression in patients with chronic obstructive pulmonary disease (COPD)and its effect on quality of life.Methods Eighty-four patients with COPD admitted to our hospital from October 2015 to December 2016 were selected as the subjects,and divided into control group and observation group by radom table method,with 42 cases in each group.The control group was given routine intervention,and the observation group was given routine intervention.Based on psychological interventions,SAS,SDS,and Pittsburgh sleep quality index (PSQI)were used to evaluate the effects of the interventions.The intervention effects of the two groups were analyzed and compared.Results The scores of SAS,SDS and PSQI after intervention in both groups were lower than those before intervention,the differences were statistically significant(P＜0.05).The SAS,SDS and PSQI after intervention in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Psychological intervention can significantly reduce the uncertainty of the disease and the psychological state of anxiety and depression in patients with COPD,which is worthy of clinical application. 2018 Vol. 25 (10): 38-40 [Abstract] ( 182 ) HTML (25 KB)  PDF (1576 KB)  ( 28 ) 41 Application of ambulatory laparoscopic cholecystectomy LI Shu-jie;GONG zi-qi;SUN kai;WANG jun;XU cai-teng Objective To explore the feasibility of ambulatory laparoscopic cholecystectomy.Methods A retrospective review of 83 patients who underwent laparoscopic cholecystectomy from June 2014 to May 2016 in our center was performed.Depending on whether the patient was operated on the day of admission and discharged within 24 h,they were divided into ambulatory group(n=38)and inpatient group(n=45).The operation time,length of hospital stay,postoperative complication and hospitalization expense were compared between the two groups.Results The differences were not statistically significant in operation time and postoperative complication incidence between the two groups(P＞0.05),while the differences were statistically significant in length of hospital stay and hospitalization expense (P＜0.05).ConclusionAmbulatory laparoscopic cholecystectomy can shorten length of hospital stay and reduce hospitalization expense significantly,which is safe and feasible. 2018 Vol. 25 (10): 41-43 [Abstract] ( 186 ) HTML (26 KB)  PDF (1622 KB)  ( 38 ) 44 Effect of Glucocorticoid combined with Cyclophosphamide in the treatment of severe systemic lupus erythematosus YU Jing Objective To investigate the clinical effect of Glucocorticoid and Cyclophosphamide in the treatment of severe systemic lupus erythematosus.Methods From July 2015 to July 2017,98 patients with severe systemic lupus erythematosus were selected as the subjects,and randomly divided into study group and control group,with 49 cases in each group.The control group was treated with Glucocorticoid,while the study group was treated with Glucocorticoid and Cyclophosphamide.The changes of SLEDAI score,ANA,ds-DNA,complement C3,immunoglobulin(IgG),urinary protein,blood creatinine(SCr)and blood urea nitrogen(BUN)were recorded before and after treatment.And the adverse reactions were compared between the two groups.Results After treatment,the indexes of the two groups were significantly improved(P＜0.05).The improvement of SLEDAI ANAds-DNA and IgG levels in the study group were significantly better than that in the control group,the improvement of the indexes of renal functions were also better than that of the control group (P＜0.05).There was no significant difference in the adverse reaction between the two groups (P＞0.05).Conclusion The combination of Glucocorticoid and Cyclophosphamide in the treatment of severe systemic lupus erythematosus can control the disease more effectively,improve the renal function of the patient,improve the clinical treatment effect,which has good safety and is worthy of clinical popularization. 2018 Vol. 25 (10): 44-46 [Abstract] ( 179 ) HTML (27 KB)  PDF (1618 KB)  ( 26 ) 47 Analysis of the correlation of prior infection with cerebral infarction and influence factors of prior infection at the different time periods ZHANG Xiao;LI Wei-hua Objective To analyze the influence factors of prior infection and its correlation with cerebral infarction at the different time periods.Methods From August 2013 to August 2017,66 cerebral infarction patients treated in our hospital were selected as study group.They were divided into infection group(14 cases)and non-infection group(52 cases).The influence factors of prior infection were analyzed.In addition,66 patients without cerebral infarction were selected as control group.At the different time periods,the correlation of prior infection with cerebral infarction was analyzed.Results The history of diabetes mellitus and coronary heart disease in infection group and non-infection group was significantly different(P＜0.05).According to the Logistic regression equation,it was known that the influence factors of cerebral infarction included the history of diabetes mellitus and coronary heart disease.Within 3 d of the prior attack,the infection rate of study group was significantly higher than that of control group (P＜0.05).At the other time periods,the infection rate of study group and control group was not significantly different(P＞0.05).Conclusion According to the influence factors of the cerebral infarction,the patients complicated with diabetes mellitus and coronary heart disease are easy to have the infection.Within 3 d of the prior attack,the infection rate for cerebral infarction patients is higher than non-cerebral infarction patients. 2018 Vol. 25 (10): 47-49 [Abstract] ( 187 ) HTML (27 KB)  PDF (1677 KB)  ( 31 ) 50 Two-way application research of ECG and blood pressure monitoring system of Central Hospital of Baoan District and community medical system LIN Xiao-feng;CHEN Huai-jing;YAN Xiao-ying;ZHAO Xi-juan;HUANG Wei-chao Objective To analyze the two-way application value of ECG and blood pressure monitoring system of our hospital and community medical system.Methods All of 3000 suspected patients with hypertension or arrhythmias were selected from September 2015 to June 2017.All patients were performed evaluating state of an illness using the electrocardiogram(ECG)and blood pressure monitoring system,and the application effect of separately ECG or blood pressure monitoring system (control group)and ECG combined with blood pressure monitoring system (observation group)was compared.Results The detection rate of hypertension and arrhythmia in the observation group was higher than those of the the control group,and the difference was statistically significant(P＜0.05).The incidence of malignant hypertension,severe arrhythmia and myocardial infarction in the observation group were significantly lower than those of the control group,and the difference was statistically significant(P＜0.05).The disability rate and mortality rate of the observation group was 0.87%,0.37%respectively,which was significantly lower than that of the control group(3.40%,1.53%),and the difference was statistically significant(P＜0.05).ConclusionTwo-way application effect of ECG and blood pressure monitoring system of Central Hospital of Baoan District and community medical system is obvious,which can effectively improve the detection rate of hypertension and arrhythmia,and at the same time reduce the incidence of malignant hypertension,severe arrhythmia and myocardial infarction,and effectively reduce the morbidity and mortality. 2018 Vol. 25 (10): 50-52 [Abstract] ( 201 ) HTML (26 KB)  PDF (1709 KB)  ( 33 ) 53 Effect observation of artificial chordae combined with bicuspid ring in the treatment of mitral prolapse complicated with insufficiency ZHU Bo-wei;CHEN Kai-ming;LAI Feng-hua;LIU Lang;LIN Shi-ting;CHEN Ze-ke Objective To investigate the clinical effect of artificial chordae combined with bicuspid ring in the treatment of mitral prolapse complicated with insufficiency.Methods Sixty-five patients with mitral prolapse complicated with insufficiency treated in our hospital from May 2014 to October 2017 were selected.They were divided into the control group (n=33)and experimental group (n=32)based on the singular and plural number of medical records.An incision was made in the middle of the sternum in patients of the experimental group,and the experimental group was treated with artificial tendon planting and mitral annuloplasty ring implantation under extracorporeal circulation while the control group was treated with mitral valve replacement.The left ventricular end diastolic diameter(LNDD),Left ventricular ejection fraction (LVEF)and left atrium diameter(LAD)before and after treatment in patients were observed.Results No death case occurred in all participants after therapy.The indicators of LNDD,LVEF and LAD in the experimental group were significantly improved compared with the control group with statistical differences (P＜0.05).The total incidence of complications in the experimental group was significantly less than that in the control group(P＜0.05).Conclusion For patients with mitral prolapse complicated with insufficiency,the effect of artificial tendon planting and mitral annuloplasty ring implantation under extracorporeal circulation is significant with few complications,which can improve the cardiac function,and has a higher value for clinical application and promotion. 2018 Vol. 25 (10): 53-55 [Abstract] ( 178 ) HTML (26 KB)  PDF (1757 KB)  ( 26 ) 56 Analysis of risk factors of aspirin resistance in patients with coronary heart disease ZHOU Li-yao;GUO Jian-hao;LI Jian-ping;CHEN Ruo-feng;WANG Jia Objective To study the risk factors of aspirin resistance in patients with coronary heart disease(CHD).Methods The clinical data of patients with CHD admitted into our hospital from January 2012 to April 2017 were retrospectively analyzed.According to inclusion and exclusion criteria,40 patients with aspirin resistance(AR group)or without AR(NAR group)were screened respectively.The general clinical data and the related laboratory indexes were compared between the two groups,and the risk factors of AR in patients with CHD were analyzed.Results The level of retinol-binding protein(RBP)in the AR group was lower than that in the NAR group while the level of creatinine(SCr),Hcy and CD62P were higher than those in the NAR group(P＜0.05).Taken AR as the dependent variable,the Hcy and CD62P were risk factors for AR in patients with CHD,and the risk value of Hcy was highest.Conclusion Hcy and CD62P are the risk factors for AR in patients with CHD,or it can be an effective index in the predicting the AR risk in patients with CHD. 2018 Vol. 25 (10): 56-58 [Abstract] ( 168 ) HTML (23 KB)  PDF (1793 KB)  ( 31 ) 59 Analysis on the related influencing factors of post-stroke depression YANG Hong-wen;TANG Chun-qiong; OU Jia-huan;YIN Jian;LI Qu-hong;NIE Ya-xiong Objective To investigate the incidence rate and related factors of post-stroke depression(PSD),so as to provide evidence for psychological treatment of ischemic stroke.Methods From January 2014 to December 2016,patients with acute stroke who met the inclusion criteria and were hospitalized in succession in the Department of Neurology of the First Affiliated Hospital of University of South China and Nanhai Hospital of Southern Medical University in Guangdong Province,Foshan were selected.384 patients with first attack of ischemic stroke who were hospitalized within 72 hours were scored by Hamilton depression rating scale and divided into the PSD group(n=116)and non PSD group(n=268)according to the assessment results.Statistical analysis of potential risk factors for depression was performed,and multiple Logistic regression analysis was carried out for statistically significant factors.Results In the PSD group,the proportion of the low education level,introverted personality,poor economic status,living alone and marital status,NIHSS score≥9 on admission,complications and infarction at key parts (frontal lobe,basal ganglia)were significantly higher than those in the non PSD group,and the differences were statistically significant(P＜0.05).Serum SSA level in patients of the PSD group([18.69±5.18]mg/L)was significantly higher than those in non PSD group([15.37±4.75]mg/L),and the differences were statistically significant(t=6.325,P＜0.001).Logistic regression analysis showed that introverted personality,economic status,living alone,NIHSS score,infarction at key parts and serum SAA level were the independent factors of PSD(P＜0.05).Conclusion Ischemic PSD is affected by many factors.Serum SAA in the prediction of ischemic PSD has a certain clinical application value. 2018 Vol. 25 (10): 59-61转64 [Abstract] ( 185 ) HTML (29 KB)  PDF (1860 KB)  ( 34 ) 62 Relevance study of cognitive dysfunction and cerebral arteriosclerosis in patients with primary Parkinson disease TANG Jun Objective To investigate the relevance of cognitive dysfunction and cerebral arteriosclerosis in patients with primary Parkinson disease.Methods Al1 of 188 patients with Parkinson disease treated in our hospital from January 2013 to June 2016 were selected as the study sbiects.The patients were given transcranial Doppler ultrasound to assess cerebral arteriosclerosis.According to the result of cerebral arteriosclerosis,they were divided into Parkinson complicated with cerebral arteriosclerosis group (group A，75 cases)and Parkinson without cerebral artery atherosclerosis group(group B,113 cases).80 cases healthy people were selected as the control group.Montreal cognitive assessment scale(MoCA)was applied to test cognitive function.The relevance of the total score of MoCA and the ultrasonic index was analyzed by Spearman.Results PI,RI of MCA and BA in group A were significantly higher than those of group B and the control group (P＜0.05).Vm，Vd of MCA and BA in group A were significantly lower than those of group B and the control group(P＜0.05).The rate of the cognitive disorder in group A was significantly higher than that of group B(χ2=12.35,P＜0.05).MoCA score of group A was significantly higher than that of group B and control group (t=8.27，5.21,P＜0.05).The total score of MoCA was negatively correlated with PI and RI of BA and MCA (r=-0.315,-0.203,-0.329,-0.214，P＜0.05).Conclusion There is a close relationship between the cognitive dysfunction and cerebral arteriosclerosis in patients with Parkinson disease.Preventive treatment of cerebral arteriosclerosis in patients with primary Parkinson disease should be carried out. 2018 Vol. 25 (10): 62-64 [Abstract] ( 183 ) HTML (25 KB)  PDF (1800 KB)  ( 30 ) 65 Short-term effects of different surgical timing treating hypertensive intracerebral hemorrhage LIU Qing-bin Objective To explore the short-term effects of different surgical timing treating hypertensive intracerebral hemorrhage.MethodsA total of 78 patients with hypertensive intracerebral hemorrhage performed with surgeries in our hospital from January 2016 to January 2017 were selected as observation subjects.They were divided into the ultra-early group(≤6 h),early group(6-24 h)and late group(≥24 h)according to different onset-to-operation time,and there were 26 cases in each group.According to the actual conditions,the corresponding surgeries were adopted.The shortterm effect and re-bleeding rate in different surgical timing among three groups were analyzed.Results There was no significant difference in the good and excellent rate or mortality rate among the ultra-early group,early group,and late group(P＞0.05).The incidence of postoperative re-bleeding in the ultra-early group was 30.77%,which was significantly higher than that in the early and late groups accounting for 7.69%and 3.85%respectively (P＜0.05).However,there was no statistical difference in re-bleeding rate in the early and late group(P＞0.05).Conclusion The three different surgical timing all can actually obtain ideal short-term effect,but the incidence of re-bleeding in the ultra-early group is higher.Therefore,early surgery can be used as the preferred surgical timing for those met the criteria,and it is safe and reliable. 2018 Vol. 25 (10): 65-67 [Abstract] ( 171 ) HTML (26 KB)  PDF (1786 KB)  ( 33 ) 68 Changes of renal tubular related indexes in IgA nephropathy combined with hyperuricemia LIU Ye-wei;SUN Ming;SUN Yi-jun;WU Wen-bin Objective To investigate the changes of renal tubular related index in patients with hyperuricemia IgA nephropathy,and understand the impact of high uric acid on renal tubules.Methods A total of 105 patients with primary IgA nephropathy treated in Yidu Central Hospital of Weifang from February 2014 to January 2016 were selected as the subjects,and divided into normal uric acid group(n=55)and hyperuricemia group(n=50).The urinary β2-microglobulin(β2-MG),N-acetyl-β-D-glucosaminidase(NAG),Retinol-binding protein(RBP),titratable acid(TA),urinary ammonium ion(NH4+),urine osmotic pressure(UOSM)were observed.Results The urinary β2-MG,RBP and NAG in high uric acid group were significantly higher than those in normal uric acid group,the difference was statistically significant(P＜0.01).There was no significant difference in urine TA,NH4+and UOSM between the two groups(P＞0.05).Conclusion Hyperuricemia has obvious damage to the proximal tubules of patients with IgA nephropathy,but it has little effect on the acidification and concentration and dilution of distal tubules. 2018 Vol. 25 (10): 68-70 [Abstract] ( 160 ) HTML (28 KB)  PDF (1854 KB)  ( 27 ) 71 Comparison ofthe three differentmethods oflithotripsy under ureteroscope in treatment of ureteral calculi(length less than or equal to 1.0 cm)the effect of contrast SHI Chong-jun;YANG Wei-zhong;YAN Ji-yin;DENG Jin-biao;ZHANG Dong-jiang;CAI Hua-ge Objective To compare the effectiveness of three different methods of lithotripsy under ureteroscope in treatment of ureteral calculi(length less than or equal to 1.0 cm).Methods From February 2015 to February 2017,169 cases of upper ureteral calculi(length less than or equal to 1.0 cm)treated in our hospital were selected as the research subjects,and divided into group A(60 cases),group B(52 cases)and group C(57 cases)according to a random table method.Group A was treated with ultrasonic lithotripsy,group B treated with ureteroscopic pneumatic ballistic lithotripsy,and group C was treated with holmium laser lithotripsy.The success rates,the rates of stone removal,the amount of bleeding in the operation,the time of postoperative hospitalization,and the incidences of complications of the three groups were compared.Results In group A and group C,the success rate of lithotripsy was higher than that in group B,the difference was statistically significant(P＜0.05),but there was no significant difference between group A and group C(P＞0.05).The rate of stone exclusion in group A was higher than that in group B and group C,the differences were statistically significant(P＜0.05).The amount of bleeding in group A was less than that in group B and group C,the differences were statistically significant (P＜0.05).The time of hospitalization in group A was shorter than group B and group C,the differences were statistically significant(P＜0.05).The incidence of complications in group A was lower than that in group B and group C,the differences were statistically significant (P＜0.05),and there was no statistical difference between group B and group C (P＞0.05).Conclusion The upper ureteral calculi(length less than or equal to 1.0 cm)patients treated with ureteroscopic lithotripsy in the treatment of ultrasound has high successful rate one time,with less bleeding,faster postoperative recovery and less complications and obvious advantages. 2018 Vol. 25 (10): 71-73转76 [Abstract] ( 172 ) HTML (30 KB)  PDF (1944 KB)  ( 32 ) 74 The changing application of PINP,CTX,OST for ANFH patients in serum WU Hua-gui Objective To approach changing of PINP,CTX,OST for ANFH patients.Methods A total of 60 cases ANFH patients in our hospital from Angust 2014 to Angust 2017 were selected as detection group,50 cases health physical examination personnel were selected as control group.The content changing of PINP,CTX,OST in two groups,content changing of PINP,CTX,OST for different age patients in serum,the content changing of PINP,CTX,OST for different stage patients in serum were detected.Results The content of PINP,CTX,OST in detection group patients were higher than that in the control group,the content of PINP,OST in＞39-49 years age group were higher than that other age groups,the content of CTX in＞49-59 years age group were higher than that other age groups,the content of PINP,OST inⅢstage patients were higher than other stage patients,the content of CTX inⅣstage patients were higher than that other stage patients,the differences were statistically significant(P＜0.05).Conclusion The PINP,CTX,OST level of ANFH patients are higher than that normal person,PINP,CTX,OST could forecast ANFH in early stage,degree of ANFH by dynamic monitoring,be beneficial to assessment for treatment result. 2018 Vol. 25 (10): 74-76 [Abstract] ( 170 ) HTML (25 KB)  PDF (1905 KB)  ( 28 ) 77 The clinical effect of external fixation in the treatment of the fracture of traumatic orthopedics QING Ju-yao Objective To investigate the clinical effect of external fixator in the treatment of traumatic orthopedic limb fractures.MethodsFrom May 2014 to December 2016,100 cases of limb fractures patients treated in our hospital were selected as observation subjects and randomly divided into observation group and control group,50 cases in each group.The observation group was treated with external fixator,while the control group was treated with internal fixation.The differences of operation time,intraoperative blood loss，hospitalization time and incision length were compared between two groups.The clinical curative effect of the two groups was observed.The complication occurred between the two groups before and after discharge were recorded.Results The operation time and hospital stay in the observation group were shorter than those in the control group,the blood loss in the observation group was less than that in the control group,and the incision length was smaller than that in the control group(P＜0.05).The fracture healing rate in the observation group was significantly higher than that in the control group(P＜0.05).The incidence of complications in the observation group was significantly lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion The external fixator is superior to internal fixation in the patients with extremities fractures,which can effectively improve the fracture healing in patients with extremities fractures,which prompts the patients to discharge as soon as possible and is worth popularizing in clinical. 2018 Vol. 25 (10): 77-79 [Abstract] ( 168 ) HTML (27 KB)  PDF (1884 KB)  ( 28 ) 80 Analysis on the clinical efficacy of negative sealing drainage in the treatment of posterior thoracolumbar surgery complicated with cerebrospinal fluid leakage DU Yong-wei;LIU Zhen;XU Fang-tian;LAI Guang-song Objective To investigate the clinical efficacy of negative sealing drainage(VSD)in the treatment of posterior thoracolumbar surgery complicated with cerebrospinal fluid leakage.Methods A total of 30 patients complicated with cerebrospinal fluid leakage who underwent posterior thoracolumbar procedure in our hospital from January 2015 to January 2017 were selected,they were divided into observation group(n=15)and control group(n=15)according to random number table.The observation group was given VSD treatment,and the control group was given conventional treatment.The clinical curative effects were compared between the two groups.Results①After different methods of treatment,the length of stay in the observation group was(8.43±1.05)d,significantly lower than that of(11.54±0.15)d in the control group;the wound healing time in the observation group was(18.1±1.4)d,significantly lower than that of(31.2±2.1)d in the control group,the differences between the two groups were significant(P＜0.05).②The incidence rate of complications in the observation group was 0.0%,which was lower than that of 40.0%in the control group,there was significant difference between the two groups(P＜0.05).ConclusionThe application of VSD in the clinical treatment of patients receiving posterior thoracolumbar surgery complicated with cerebrospinal fluid leakage can effectively shorten the length of stay,reduce the risk of complications and improve the prognosis,which is worthy of application in clinical practice. 2018 Vol. 25 (10): 80-82 [Abstract] ( 164 ) HTML (27 KB)  PDF (1933 KB)  ( 34 ) 83 Application effect comparison of internal fixation and conservative treatment in the treatment of multiple fractures of the ribs LIANG Rui-yu;LIANG Jin-song;RAO Xin-hui;ZHANG Zi-zheng;LI Jian-ming;ZHONG Hai-hui;ZHANG Huan-rong Objective To compare the curative effect of internal fixation and conservative therapy on treating multiple rib fractures of the ribs.Methods A total of 54 patients with multiple rib fractures from November 2012 to August 2017 admitted into our hospital were selected as research objects.They were evenly divided into control group(conservative therapy)and observation group (internal fixation)by a random number table,27 cases in each group.The degree of pain and postoperative recovery of the indicators before and after treatment were compared in the two groups.Results The total effectiveness rate in the observation group was 100.00%,significantly higher than that in the control group accounting for 85.19%(P＜0.05).There was no significant difference in visual analogue scale(VAS)score before treatment and first day after therapy in the two groups(P＞0.05).On days 3 and 7 after treatment,the scores of VAS in the observation group were significantly lower,compared with that in the control group(P＜0.05).In the observation group,the time of being forced to stay in bed,pleural canal indwelling time,time of using analgesics,and hospital stay were all shorter compared with those in the control group.The thoracic cavity drainage in the observation group was significantly less compared with that in the control group,with a statistical difference(P＜0.05).Conclusion Compared with traditional conservative therapy,application of internal fixation in the treatment of multiple fractures of the ribs can obtain more reliable and definite effects by effectively relieving patient′s suffering and shortening the recovery of fractures,which plays a critical role in promoting the early recovery of patients. 2018 Vol. 25 (10): 83-85 [Abstract] ( 156 ) HTML (27 KB)  PDF (1939 KB)  ( 35 ) 86 Effect of exercise therapy and physical agents in the treatment of knee osteoarthritis JIN Yan1ZHAO Xin1ZHENG Rui-hong2▲ Objective To investigate the effect of exercise therapy combined with physical agents on knee osteoarthritis(KOA)and provide guidance for clinical practice.Methods From February 2013 to October 2017,300 KOA patients in our hospital were enrolled as research objects.They were randomly divided into single group(n=150,physical agents alone)and combined group(n=150,exercise therapy with physical agents).The scores of pain,activities of daily living,and knee function in the two groups were compared.Results In the combined group,the score of the activity of daily living was significantly higher than that in the single group（[78.24±2.32]points vs.([65.20±2.78]points)(P＜0.05).The postoperative pain score in the combined group was （2.12±0.52） points,which was much lower than that in the single group （[4.02±0.67]points） （P ＜0.05）.The excellent and good rate of knee joint function in the combined group was 82.67%,significantly higher than that in the single group accounting for 71.33%,the differences were statistically significant（P＜0.05）.Conclusion Exercise therapy combined with physical agents in the treatment of KOA has a good effect,and can significantly improve patient′s knee joint function. 2018 Vol. 25 (10): 86-88 [Abstract] ( 168 ) HTML (26 KB)  PDF (1935 KB)  ( 30 ) 89 Initial effect analysis of single condylar arthroplasty and total knee arthroplasty for the treatment of medial single compartment osteoarthritis of the knee joint CHEN Kang-yao;GU En-yi;ZHENG Zhong Objective To investigate the clinical effect of total knee arthroplasty(TKA)and unicompartment knee arthroplasty (UKA)in treating knee joint medial unicompartmental osteoarthritis.Methods From November 2015 to July 2016,80 patients with osteoarthritis of the knee in our hospital were enrolled and randomly divided into two groups,40 patients in the control group were treated with TKA,and 40 patients in the observation group were treated with UKA,and the clinical efficacy of the two groups was compared.Results The operation time and the first straight leg raised time of the observation group were shorter than those of the control group,and the amount of bleeding during the operation of the observation group were lesser than that of the control group,the differences were statistically significant(P＜0.05).The VAS score of the observation group was lower than that of the control group first days after the operation,and the length of the incision was shorter,the differences were statistically significant(P＜0.05).After 3 months of treatment,there was no significant difference in the VAS score and the Lysholm score in the two groups(P＞0.05).Conclusion Both TKA and UKA are important means for the treatment of medial unilateral osteoarthritis of the knee,with the same efficacy,but the latter has advantages of less trauma and faster recovery,and is worthy of promotion. 2018 Vol. 25 (10): 89-91 [Abstract] ( 137 ) HTML (28 KB)  PDF (1990 KB)  ( 33 ) 92 The curative effect of cervical dilatation balloon for cervical ripening CHEN Huan-qing;HUANG Xue-min;CAO Xiu-qun;ZHANG Xiao-yan;MO Xi-ping;WANG Ying;CHEN Xing-mei;CHEN Bi-xia Objective To study the curative effect of cervical dilatation balloon for cervical ripening.Methods All of 120 pregnant women who gave birth in Yunfu maternal and child health and family planning service center from June 2016 to May 2017 and had indications for induced labor were randomly divided into balloon group and control group with 60 cases in each group.Balloon group cervical dilatation balloon to promote cervical ripening,control group using oxytocin to promote cervical ripening.The cervical ripening,total labor time,cesarean section rate and neonatal conditions were compared between the two groups.Results The total effective rate of cervical ripening in balloon group was significantly higher than that in control group,and the difference was statistically significant(P＜0.05);during the childbirth,the time from drug use to delivery,the time of the first stage of labor,the time of the second stage of labor and the time of the third stage of labor of balloon group were shorter than those of control group,and the differences were statistically significant(P＜0.05);after childbirth,the postpartum hemorrhage volume of balloon group was less than that of control group and the difference was statistically significant(P＜0.05),the rate of cervical laceration,caesarean section were lower than those of control group,and the differences were statistically significant(P＜0.05).There was no statistically significant in Apgar score between the two groups(P＞0.05).Conclusion The cervical dilatation balloon can promote the cervical ripening of the cervix with poor cervical conditions.After the balloon is taken out,the labor induction can be carried out successfully,and the success rate of induced labor is improved,which is safe and effective for pregnant women with small injury. 2018 Vol. 25 (10): 92-94转98 [Abstract] ( 138 ) HTML (29 KB)  PDF (2026 KB)  ( 33 ) 95 Changes and clinical significance of KL-6 and PAI-1 in the blood of children with wheeze less than 5 years old GUO Cai-yun;ZHANG Jin-feng; WEI Chu-hong;YAO Long-yan;SUN Yan-na Objective To investigate the changes and clinical significance of KL-6 and Plasminogen activator inhibitor-1(PAI-1)in children with wheezing less than 5 years old.Methods A total of 198 children under 5 years of age with wheezing symptoms diagnosed and treated in our hospital from January 2015 to December 2016 were selected and randomly divided into API positive group(n=104)and API--negative group(n=94)according to API scoring criteria.Patients in the two groups were inhaled budesonide suspension and bricanyl at 1-4 weeks,and only treated with montelukast sodium orally at 4 weeks.the asthma symptom scores were recorded before treatment,4,8 and 12 weeks after treatment,and the expression levels of KL-6 and PAI-1 in blood were detected.Results There was no significant difference between KL-6 and PAI-1 in API negative group(P＞0.05).The expression of KL-6 and PAI-1 in API-positive group decreased with the treatment time(P＜0.05),and the expression of KL-6 and PAI-1 in API-positive group was significantly higher than that in API-negative group(P＜0.05).There was no significant difference in KL-6 and PAI-1 expression between the two groups at 12 weeks after treatment(P＞0.05).There was no significant difference in asthma symptom score between the two groups before treatment(P＞0.05).The symptom scores of asthma decreased significantly at 4,8 and 12 weeks after treatment,the difference was statistically significant(P＜0.05).The scores of asthma symptoms in API positive group were significantly lower than those in API negative group at 4 and 8 weeks after treatment,the difference was statistically significant(P＜0.05);there was no significant difference in the scores of asthma symptoms between the two groups at 12 weeks after treatment(P＞0.05).Conclusion The expression of KL-6 and PAI-1 in the asthmatic children less than 5 years old is in a dynamic state and associates with the symptom score of asthma. 2018 Vol. 25 (10): 95-98 [Abstract] ( 163 ) HTML (32 KB)  PDF (2036 KB)  ( 39 ) 99 Clinical analysis of antibiotics combined erswith glucocorticoid in the treatment of severe mycoplasma pneumonia in children YUAN Yan;XU Wang;HU Hua-zhu;YI Yi-jiang;YUAN Mei-mei Objective To investigate the clinical efficacy of antibiotics combined with glucocorticoid in the treatment of severe mycoplasma pneumonia in children.Methods 70 children with severe mycoplasma pneumonia diagnosed and treated in our hospital from March 2016 to December 2017 were selected as the research object,and randomly divided into control group and observation group,35 cases in each group.The control group was treated with antibiotics,while the observation group was treated with glucocorticoids.The total effective rate,fever reduction time,hospitalization time,antibiotic use time,CRP and other indicators were compared between the two groups.ResultsThe total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05);The duration of fever reduction,hospitalization and antibiotic use in the observation group were shorter than those in the control group(P＜0.05),and CRP index in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion The combination of antibiotics and glucocorticoids in the clinical treatment of children with severe mycoplasma pneumonia can effectively promote the improvement of clinical treatment effect,therefore,the clinical value is significant. 2018 Vol. 25 (10): 99-100转104 [Abstract] ( 148 ) HTML (23 KB)  PDF (1979 KB)  ( 29 ) 101 Epidemiological research on the risk factors of cervical precancerous lesions or HPV positivity ZHANG Shan-shan;DING Mei Objective To observe the infection of HPV in cervical precancerous lesion group and cervical cancer group in order to explore the correlation between different subtypes of HPV and cervical precancerous lesions as well as cervical cancer.Methods A total of 101 134 patients treated in our hospital from January 2015 to November 2016 were selected as research objects.According to the pathological results,they were divided into three groups:cervical cancer group(n=19 368),cervical precancerous lesion group(n=36 361),and cervicitis group(n=45 405).The positivity rate of HPV was calculated after HPV test and HPV-DNA subtype detection.Results Among HPV positive infection cases,the positivity rate of HPV in the cervicitis group was significantly lower than that of the cervical precancerous group(χ2=43.21,P＜0.05),and the positivity rate of HPV in the cervical precancerous lesion group was greatly higher compared with that in the cervical cancer group(χ2=53.21,P＜0.05),which were displayed statisticaldifferences.The main subtypes in the cervical cancer group were infection of HPV16 and HPV18 accounting for 49.97%and 41.12%,respectively.For CINⅠpatients in the cervical precancerous lesion group,the infection of HPV52,HPV33,and HPV16 were the main subtypes accounting for 35.33%,12.50%,and 19.63%,accordingly.For CINⅡpatients in the cervical precancerous lesion group,the infection of HPV58,HPV18,and HPV16 were the main subtypes,25.64%,23.14%,and 16.25%accordingly.For patients with CINⅢin the cervical precancerous lesion group,the infection of HPV58,HPV52,and HPV16 were the main subtypes accounting for 18.82%,18.59%,and 36.90%.In the cervical cancer group,participants were only presented with single infection,withoutdouble,triple or multiple infection.In the cervical precancerous lesion group,double infection rates in CIN,CIN,and CINⅢpatients were significantly higher than those in triple and multiple infection.Conclusion In the cervical precancerous lesion group,the main subtypes of HPV infection are HPV 16,HPV 18,HPV 52,and HPV 58.In the cervical cancer group,the two main subtypes of HPV infection are HPV 18 and HPV 16.On multiple infection rate,the cervical precancerous lesion group was higher compared with that in the cervical cancer group.HPV detection has a higher effectiveness in the prevention and treatment of cervical diseases,which can help patients understand and prevent cervical lesions in advance.It is of great significance on the disease prevention,control and prognosis evaluation. 2018 Vol. 25 (10): 101-104 [Abstract] ( 125 ) HTML (30 KB)  PDF (2024 KB)  ( 28 ) 105 Clinical effect of different blue light irradiation methods in the treatment of neonatal jaundice GUO Qun-xi;LI Li Objective To comprehensive analyze the clinical effects of different blue light irradiation methods in the treatment of neonatal jaundice.Methods A total of 108 cases of jaundice in children were selected from December 2014 to December 2016 treated in our hospital,and divided into experimental group and control group according to the random number table method of different blue light irradiation,54 cases in each group.The clinical efficacy,incidence of adverse reactions and effects on liver function(total bilirubin,alanine aminotransferase and alkaline phosphatase),cytokine(C-reactive Protein,transferrin)were analyzed.Results The total effective rate of the experimental group was significantly higher than that of the control group,the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in liver function and cytokine levels between the two groups(P＞0.05).After treatment,the level of liver function and cytokine in the experimental group was significantly higher than that in the control group,the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the experimental group was significantly lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion The efficacy of intermittent blue light irradiation in the treatment of neonatal jaundice is significantly better than that of the continuous blue light irradiation. 2018 Vol. 25 (10): 105-107 [Abstract] ( 144 ) HTML (27 KB)  PDF (2011 KB)  ( 17 ) 108 Risk factors a nalysis for postpartum hemorrhage in caesarean section patients due to placenta previa LIANG Dong-ru;ZHANG Hong-hua;CHEN Xiao-ling Objective To investigate the risk factors of postpartum hemorrhage in caesarean section patients due to placenta previa.MethodsThe clinical data of 57 cases of placenta previa hospitalized in our hospital from March 2016 to July 2017 were retrospectively analyzed.according to whether postpartum hemorrhage occurred after cesarean section,the patients were divided into postpartum hemorrhage group and non postpartum hemorrhage group.The general clinical data and suspected risk factors of the two groups were collected,and the univariate and multivariate logistic regression analysis was used to explore the risk factors of postpartum hemorrhage after cesarean section of placenta previa.Results There were 17 cases of postpartum hemorrhage in 57 cases of placenta previa cesarean section,the incidence rate was 29.82%.There were statistically significant differences between the two groups in the delivery time,placenta previa attachment site,placenta previa type,prenatal hemorrhage,gestational age of the first prenatal hemorrhage and placenta accreta(P＜0.05).Multivariate analysis showed that placenta previa attached to the anterior wall,central placenta previa,prenatal hemorrhage,placenta implantation were the risk factors of postpartum hemorrhage in patients with placenta previa cesarean section.Conclusion There are many risk factors influencing on postpartum hemorrhage after cesarean section due in placenta previa.Targeted on the relevant risk factors,prevention and intervention should be given in order to reduce the incidence of cesarean section postpartum hemorrhage in placenta previa. 2018 Vol. 25 (10): 108-110 [Abstract] ( 166 ) HTML (26 KB)  PDF (2011 KB)  ( 32 ) 111 Effect of acceptance of professional individualized pregnancy diet guidance on pregnancy outcome YAN Jin-qun;MAI Yan-tao Objective To explore the effect of acceptance of professional individualized pregnancy diet guidance on pregnancy outcome.Methods All of 180 pregnant women diagnosed and treated in our hospital from February 2016 to August 2017 were selected as observation objects,and randomly divided into control group and observation group,90 cases in each group.The pregnant women in the routine group received routine prenatal examination and health education.on the basis of routine group,the pregnant women in the specialized group received professional individualized diet guidance.The delivery mode,nutritional status during pregnancy,complications during pregnancy,complications during delivery,postpartum recovery and neonatal status of the two groups were statistically compared.Results In terms of delivery mode,the vaginal delivery rate of pregnant women in the professional group was significantly higher than that in the conventional group(χ2=15.8026,P＜0.05).The nutritional status during pregnancy,postpartum recovery and neonatal health in the professional group were significantly better than those in the conventional group(P＜0.05).The incidence of pregnancy hypertension,pregnancy diabetes and postpartum hemorrhage in the professional group was lower than that in the conventional group(P＜0.05).In the professional group,there were 0 macrosomia and 1 low birth weight(1.11%).In the conventional group,6 cases(6.67%)were macrosomia and 8 cases(8.89%)were low birth weight.The incidence of neonatal complications in the professional group was lower than that in the conventional group(χ2=6.2069,5.7309,P=0.0127,0.0166).Conclusion The professional individualized diet guidance during pregnancy is very significant for the pregnancy outcome.It can not only improve the nutritional status of pregnant women,but also reduce the occurrence of complications,maximize the safety of mothers and infants,which is worthy of further clinical reference and application. 2018 Vol. 25 (10): 111-113 [Abstract] ( 164 ) HTML (27 KB)  PDF (2047 KB)  ( 35 ) 114 Application effect of Iron Proteinsuccinylate Oral Solution in iron deficiency anemia during pregnancy ZHOU Juan-fang Objective To study the application effects of Iron Proteinsuccinylate Oral Solution in iron deficiency anemia during pregnancy.Methods A total of 482 cases of iron deficiency anemia in pregnancy were selected from March 2015 to March 2016 in our hospital.The patients were divided into control group(multi-dimensional iron oral liquid)and observation group treated(protein iron succinate oral liquid),241 cases in each group.The adverse reaction rates of the two groups were observed,the red blood cell related indicators and iron metabolism level were detected,and the effective rates of the two groups were statistically analyzed.Results The adverse reaction rates of dizziness,headache,nausea and vomiting,epigastric pain and anorexia in the observation group were significantly lower than those in the control group(p＜0.05).After treatment,hemoglobin(Hb),erythrocyte count(RBC),hematocrit((HCT),reticulocyte(Ret),iron metabolism indexes of blood iron(SI)and serum ferritin(SF)in the two groups were significantly improved compared with those before treatment.the improvement of each index in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).The total effective rate of the two groups was higher in the observation group than in the control group(P＜0.05).The effective rate of the observation group was significantly higher than that of the control group(P＜0.05).Conclusion Iron Proteinsuccinylate Oral Solution can effectively reduce the incidence rate of adverse reactions,improve the levels of red blood cell related indexes and iron metabolism in patients with anemia during pregnancy,and enhance the treatment effective rate,therefore it is worthy of clinical promotion. 2018 Vol. 25 (10): 114-116 [Abstract] ( 157 ) HTML (27 KB)  PDF (2055 KB)  ( 30 ) 117 Application of hypersensitive C reactive protein in determination and prediction of severe infection in children with fever ZHONG Xi-biao Objective To analyze the effectiveness of application of hypersensitive C-reactive protein(hs-CRP)in determination and prediction of severe infection of children with fever.Methods 90 children with acute fever admitted to our hospital from November 2016 to November 2017 were selected as the study group.According to the infection situation,they were divided into severe infection group,local infection group and non-infection group,30 cases in each group,and 30 healthy children who underwent routine physical examination in our hospital during the same period were selected as the control group.All children were tested for hs-CRP by immunonephelometry,and the results were compared to evaluate the value of hs-CRP in the diagnosis and prediction of severe infection in children with acute fever.Results The level of hs-CRP in non-infected group was higher than that in control group (P＞0.05).The levels of hs-CRP in severe infection group and local infection group were significantly higher than those in control group (P＜0.05).The levels of hs-CRP in severe infection group and local infection group were significantly higher than those in non-infection group(P＜0.05).The level of hs-CRP in severe infection group was significantly higher than that in local infection group(P＜0.05).The hs-CRP levels of children in non-infection group,local infection group and severe infection group were significantly lower than those in control group(P＜0.05),and the hs-CRP levels of children in local infection group and severe infection group were significantly higher than those in control group(P＜0.05).The composition ratio of hs-CRP ＜ 10 mg/l in local infection group and severe infection group was significantly lower than that in non-infection group,and the composition ratio of 10-20 mg/l in local infection group was significantly higher than that in non-infection group and severe infection group.The composition ratio of＞20 mg/l in local infection group and severe infection group was significantly higher than that in non-infection group(P＜0.05).The hs-CRP levels of children in severe infection group were lower than those in local infection group (10 mg/l,10-20 mg/l),and those in severe infection group were higher than those in non-infection group and local infection group(P＜0.05).The positive rates of hs-CRP in four groups were statistically significant(P＜0.05).After treatment,the levels of hs-CRP in severe infection group,local infection group and non-infection group were significantly lower than those before treatment(P＜0.05).Conclusion hs-CRP plays a higher application value in determination and prediction of severe infection of children with fever prediction.With the aggravation of infection symptoms in children,the level of hs-CRP increases and the post-treatment hs-CRP level significantly decreases,suggesting that hs-CRP can be used as a reference index for determination and prediction of severe infection in emergency fever children. 2018 Vol. 25 (10): 117-120 [Abstract] ( 146 ) HTML (34 KB)  PDF (2147 KB)  ( 31 ) 121 Effect and safety analysis of Ibuprofen Suspension in treating pediatric fever LIU Chang-hai;XIAO Hui-qiong Objective To study the efficacy and safety of Ibuprofen Suspension in the treatment of fever in children.Methods From February to July 2017,100 children with fever treated in our hospital were randomly divided into control group and observation group,50 cases in each group.The control group was treated with Jinlian Qingre Granules,while the observation group was treated with Ibuprofen Suspension.The total effective rate,antipyretic time,adverse reactions,sleep quality and quality of life before and after treatment were compared.Results The total effective rate of the observation group was higher than that of the control group(P＜0.05）.The antipyretic time([1.02±0.25]h)in the observation group was shorter than that in the control group([3.54±0.54]h),the difference was statistically significant(t=29.945,P=0.000).The total incidence of adverse reactions in the observation group was lower than that in the control group(P＜0.05）.Before treatment,there was no significant difference in sleep quality score and quality of life score between the two groups (P＞0.05).After treatment,the scores of sleep quality and quality of life in the observation group were better than those in the control group(P＜0.05）.Conclusion The Ibuprofen Suspension has a significant effect in the treatment of pediatric fever,and can shorten the time of abating fever and ensure the sleep quality and quality of life in children,which deserves clinical promotion. 2018 Vol. 25 (10): 121-123 [Abstract] ( 129 ) HTML (27 KB)  PDF (2113 KB)  ( 36 ) 124 Influence of Doula accompanied delivery mode on delivery outcomes WANG Yu-ling Objective To investigate the effect of Doula accompanied delivery mode on delivery outcomes.Methods From June 2017 to December 2017,80 cases of maternal clinical data were randomly divided into control group and experimental group,40 cases in each group.The control group was accompanied by conventional midwives,while the experimental group was accompanied by doula delivery.The quality of delivery was compared between the two groups.Results The pain degree of parturient in the experimental group was less than that in the control group,the difference was statistically significant(P＜0.05).The total duration of labor in the experimental group was shorter than that in the control group,and the amount of bleeding 2 h after delivery was less than that in the control group,the difference was statistically significant(P＜0.05).Conclusion In the process of maternal delivery accompanied with Doula is beneficial to improve intrapartum quality,shorten the labor stage,reduce amount of bleeding,and alleviate pain. 2018 Vol. 25 (10): 124-126 [Abstract] ( 142 ) HTML (26 KB)  PDF (2137 KB)  ( 29 ) 127 Effect of aerosol inhalation combined with routine therapy on neonatal aspiration pneumonia and cytokines YE Ming-yi;CHEN Wei-zhong;HUANG Jun-ye;WANG Yu Objective To evaluate the effect of aerosol inhalation combined with conventional therapy on neonatal aspiration pneumonia and cytokines.Methods 99 neonates with inhalation pneumonia treated in our hospital from March 2015 to March 2017 were randomly divided into control group,observation group and experimental group.33 cases in each group were given routine treatment of control group.the observation group was treated with aerosol inhalation of ambroxol combined with routine treatment.the experimental group was treated with budesonide aerosol inhalation on the basis of routine treatment.the clinical efficacy,PO2/FiO2value and interleukin-6 level of the three groups were observed and compared.Results The disappearance time and average hospitalization time of main symptoms in the observation group and the experimental group were shorter than those in the control group(P＜0.05).After the treatment,the total effective rate of the experimental group and the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).During the treatment,PO2/FiO2in the observation group and the experimental group were significantly higher than those in the control group at different time periods(P＜0.05).After the treatment,the levels of Interleukin-6 in the three groups were decreased,and the levels of Interleukin-6 in the observation group and the experimental group were lower than those in the control group,the difference was statistically significant(P＜0.05).Conclusion Aerosol inhalation for neonatal aspiration pneumonia can significantly improve efficacy,ameliorate lung ventilation function and shorten oxygen-dependent time.The study also indicates the higher the level of interleukin-6 measures,the lower the PaO2/FiO2,and the more severe pulmonary ventilation dysfunction becomes,which has a clinical application value. 2018 Vol. 25 (10): 127-129转136 [Abstract] ( 152 ) HTML (30 KB)  PDF (2238 KB)  ( 29 ) 130 Analysis and study on the clinical value of MR plain scan and MRCP imaging in the diagnosis of duodenal diverticulum LI Hong-yi; LIU He;YANG Jing-yao; DONG Shuang;HU Ming-cheng;YIN Yan-wei;XING Jian;HU Zhi-wen Objective To analyze the MRI and magnetic resonance cholangiopancreatography(MRCP)manifestations of duodenal diverticulum,and to expore the clinical value and significance of periampullary diverticulum(PAD).Methods 46 patients with duodenal diverticulum who underwent MRI and MRCP confirmed by upper gastrointestinal tract imaging,cholangiography or endoscopy from October 2015 to October 2017 were retrospectively analyzed.The diverticulum location,size and signal characteristics,as well as the correlations between bile duct,pancreas and other associated signs were analyzed.Results There were a total of 49 diverticula in 46 patients with duodenal diverticulum,43 of whom were single diverticulum,and 3 of whom were multiple diverticula.Most of them were with the diameter of 10-25 mm.18(40.82%)diverticula contained fluid alone,without gas composition;3(6.12%)diverticula contained gas alone,without fluid composition;23(53.06%)diverticula contained gas-liquid mixture and gas-liquid level;5(10.20%)diverticula contained mixed ingredients such as food residues.Conclusion MRI and MRCP have a high accuracy in the diagnosis of duodenal diverticulum,which has an important guiding significance for clinical treatment. 2018 Vol. 25 (10): 130-132 [Abstract] ( 160 ) HTML (27 KB)  PDF (2191 KB)  ( 32 ) 133 Analysis of the value of CT diagnosis of infantile giant cystic lesions in abdomen YAN Lin;WU Zheng-ping Objective To explore the effect of CT diagnosis of infantile giant cystic lesions in abdomen.Methods 35 cases of infant giant cystic lesions in abdomen patients diagnosed and treated in our hospital from June 2016 to May 2017 were selected.According to the different diagnostic methods,they were divided into CT group and MRI group.The CT group included 18 patients,group MRI included 17 patients;the patients were treated by correlation method used to analyze the diagnostic results after examination.Results The diagnostic accuracy of CT group was higher than that of MRI group,and the sensitivity and specificity of CT group were higher than those of MRI group(P＜0.05).Conclusion the accuracy of CT diagnosis of giant cystic lesions in abdomen of infants was higher than that of MRI,and the location of the lesion,with clear display form.Therefore,the diagnosis of CT has good application value in the detection of infant giant cystic lesions in abdomen. 2018 Vol. 25 (10): 133-136 [Abstract] ( 135 ) HTML (30 KB)  PDF (2221 KB)  ( 28 ) 137 Effect of Nimotuzumab combined with Cisplatin and Fluorouracil in the treatment of advanced nasopharyngeal carcinoma WU Zhi-ying;SHU Yu-xian Objective To investigate the effect of Nimotuzumab combined with Cisplatin and Fluorouracil in the treatment of advanced nasopharyngeal carcinoma.Methods A total of 50 patients with advanced nasopharyngeal carcinoma treated in Jiangxi Cancer Hospital from January 2014 to January 2012 were selected as subjects and divided into control group and the observation group by random lottery method,25 cases in each group.The control group received chemotherapy with Cisplatin and Fluorouracil.The observation group was treated with Cisplatin and Fluorouracil combined with Nitozumab chemotherapy.After 2 years follow-up,the clinical efficacy of the two groups was compared.Results The 2-year survival rate of the patients in the observation group was 88.0%,which was significantly higher than that in the control group(60.0%),and the difference was significant(P＜0.05).The QOL improvement rate of patients in the observation group was higher than that in the control group,and the difference was significant(P＜0.05).Conclusion Combined with Cisplatin and Fluorouracil in patients with advanced nasopharyngeal carcinoma,the survival time of patients can be prolonged and the quality of their life can be improved.It is worthy of clinical popularization. 2018 Vol. 25 (10): 137-139 [Abstract] ( 153 ) HTML (28 KB)  PDF (2221 KB)  ( 26 ) 140 Clinical observation of Dexamethasone combined with Gamma Globulin in the treatment of children with Henoch-Schonlein purpura nephritis XIE Jin-jin;XIAO Zhen;YUAN Hong-ling Objective To investigate the clinical effect of Dexamethasone combined with Gamma Globulin in the treatment of children with Henoch-Schonlein purpura nephritis (HSPN).Methods The clinical data of 50 children with HSPN who were treated in our hospital from March 2014 to March 2017 were analyzed,all the patients were divided into the control group (n=20)and observation group (n=30)according to different treatment methods.The control group was treated with Dexamethasone,while the observation group was treated with Dexamethasone combined with Gamma Globulin.The pre-operative and post-operative fibrinogen(FIB),prothrombin time(PT),activated partial thromboplastin time(APTT),24 h urine protein and urine red blood cell levels of two groups were observed,and the clinical efficacy of the two groups was observed.Results The pre-operative and post-operative PT of two groups had no statistically significant difference (P＞0.05).The pre-operative FIB,APTT,24 h urine protein and urine red blood cell levels of two groups had no statistically significant difference(P＞0.05).The post-operative FIB of control group and observation group were(2.9±0.3)g/L and(2.0±0.2)g/L respectively,the 24 h urine protein were(0.14±0.03)g and(0.10±0.02)g respectively,the urine red blood cell levels were(1.9±0.4)×107 and(1.1±0.5)×107respectively,which were both lower than pre-operative levels of FIB ([3.6±0.2]g/L,[3.7±0.3]g/L),the 24 h urine protein([0.18±0.05]g,[0.19±0.06]g),the urine red blood cell([4.8±0.4]×107,[4.7±0.5]×107)respectively,the post-operative APTT of control group and observation group were (26.0±1.8)s and (28.9±2.1)s respectively,which were higher than pre-operative levels of APTT ([24.0±2.2]s,[23.9±2.0]s)respectively,while the post-operative FIB,24 h urine protein and urine red blood cell levels of the observation group were lower than those of the control group,and the postoperative APTT of the observation group was higher than that of the control group,the differences were statistically significant(P＜0.05).The total effective rate of the observation group was 96.7%,which was higher than that of the control group(80.0%),with statistically significant difference(P＜0.05).Conclusion Application of combination of dexamethasone and gamma globulin in the treatment of children with Henoch-Schonlein purpura nephritis has good effect and significant improvement in coagulation function,24h urinary protein and urine red blood cell levels,which is worthy of clinical application. 2018 Vol. 25 (10): 140-143 [Abstract] ( 160 ) HTML (31 KB)  PDF (2255 KB)  ( 23 ) 144 Therapeutic effect comparison of different drugs on superficial gastritis LI Gui-hua;TIAN Fu-hong Objective To compare the clinical efficacy of Ranitidine and Omeprazole in the treatment of superficial gastritis.Methods From May 2016 to May 2017,88 patients with superficial gastritis treated in Manasi Jiayuan Hospital were selected as subjects.They were randomly divided into the study group and the control group,44 cases in each group.The study group was were treated with Omeprazole,the control group was treated with Ranitidine,and the two group was treated for 3-7 weeks.The curative effect,adverse reaction and time of treatment were compared between the two groups.Results The average treatment time of the patients in the study group([2.67±0.21]weeks)was shorter than that in the control group([4.44±0.39]weeks),and the difference was statistically significant(P＜0.05).The total effective rate of clinical treatment in the group was 93.18%,and the total effective rate of clinical treatment in the control group was 90.91%,the difference between the two groups was not statistically significant(P＞0.05).The total incidence of adverse reactions in the study group was 13.64%,and the total incidence of adverse reactions in the control group was 15.91%,the difference between the two groups was not statistically significant(P＞0.05).Conclusion The treatment of superficial gastritis through Omeprazole can rapidly improve the symptoms of the patients,and the curative effect is positive.It is suitable for clinical application. 2018 Vol. 25 (10): 144-146 [Abstract] ( 178 ) HTML (28 KB)  PDF (2222 KB)  ( 36 ) 147 Feasibility analysis of Montelukast Sodium as an adjuvant treatment for Mycoplasma pneumonia in children TAO Meng-jie Objective To investigate the feasibility of Montelukast Sodium as an adjuvant treatment in children with Mycoplasma pneumonia by observing their clinical manifestations.Methods Sixty-two children with Mycoplasma pneumonia who were treated in our hospital from August 2014 to July 2016 were selected as subjects.They were divided into the control group (n=30)and observation group (n=32)according to the random number table method.In the control group,pediatric patients were treated with intravenous infusion of Azithromycin and aerosol inhalation of Budesonide,while in the observation group,on the basis of the control group,Montelukast Sodium as oral administration was added.The relative clinical data including total therapeutic effectiveness rate,remission time of relevant symptoms,hospital stay,incidence of complications,and blood gas analysis were observed and recorded in the two groups.Results The therapeutic effectiveness rate in the observation group was significantly higher than that of the control group,and the difference was statistically significant(P＜0.05).The remission time of cough,temperature lowering,disappearance of rales and hospital stay in the observation group were all shorter compared with those in the control group,the incidence of extrapulmonary complications was also lower than that of the control group,and the differences were statistically significant(P＜0.05).The forced expiratory volume in one second(FEV1),the forced expiratory volume in one second/forced vital capacity (FEV1/FVC),maximum expiratory flow (PEF)were all superior to those in the control group,and the differences were statistically significant(P＜0.05).The content of PO2in the observation group was higher than that in the control group,and the content of PCO2was lower than that in the control group,which were displayed statistical significance(P＜0.05).Conclusion In the treatment of children with Mycoplasma pneumonia,Montelukast Sodium can obtain a remarkable effect by greatly promoting therapeutic progress and improving the relevant clinical symptoms,and facilitating the recovery of lung function in children in high safety,which can be popularized and applied in clinic. 2018 Vol. 25 (10): 147-149转153 [Abstract] ( 132 ) HTML (32 KB)  PDF (2247 KB)  ( 30 ) 150 Clinical effect of Amlodipine Besylate and Atorvastatin Calcium Tablets in treatment of hypertension complicated with coronary heart disease ZHONG Jie-zhu Objective To investigate the clinical effect of Amlodipine Besylate and Atorvastatin Calcium Tablets in treatment of hypertension complicated with coronary heart disease.Methods A total of 80 patients with hypertension complicated with coronary heart disease who treated in our hospital from August 2015 to March 2017 were selected as subjects,and were divided into two groups according to the random digital table method,with 40 cases in each group.The control group were received the Atorvastatin Calcium Tablets treatment,while the study group were received Amlodipine Besylate and Atorvastatin Calcium Tablets treatment.The therapeutic effect,blood pressure,blood lipid and inflammatory factors before and after treatment of the two groups were compared.Results The total effective rate of the patients in the study group(92.50%)was higher than that in the control group(77.50%),and the difference was statistically significant(P＜0.05).Before treatment,the SBP,DBP,HDL-C,LDL-C,TG,TC,ET,NO,vWF,TNF-α,IL-6 and CRP in the two groups were compared,and the differences were not statistically significant(P＞0.05).After treatment,the HDL-C and ET of the two groups were compared,and the differences were not statistically significant(P＞0.05),while the SBP,DBP,LDL-C,TG,TC,vWF,TNF-α,IL-6 and CRP in the study group were both lower than those in the control group,the NO was higher than that in the control group,and the differences were statistically significant(P＜0.05).Conclusion The Amlodipine Besylate and Atorvastatin Calcium Tablets in treatment of hypertension complicated with coronary heart disease which can significantly improve the blood pressure,heart rate and other indicators,and can relieve the symptoms of the disease,and the clinical effect are outstanding,to achieve the purpose of improving the quality of life,thus it is worth of application and promotion. 2018 Vol. 25 (10): 150-153 [Abstract] ( 146 ) HTML (29 KB)  PDF  (0 KB)  ( 36 ) 154 Effect of Shenfu Injection on immune function and prognosis of patients with severe trauma ZENG Xian-guo;CHEN Li-xin;CHEN Zi-li;SONG Jing-chun Objective To investigate the effect of Shenfu Injection on the patients with severe trauma and the effect on the immune function and the prognosis of the patients.Methods A total of 80 patients with severe trauma treated in our hospital from January 2016 to June 2017 were selected as subjects and randomly divided into the control group and the control group according to the random digital table method,40 cases in each group.The control group was treated by conventional treatment,and the observation group was treated with Shenfu Injection for 7 days as one course of treatment.The two groups of immune functions indexes (NK cells,CD4+/CD8+,CD3+)were compared,and the mortality of the two groups and the incidence of multiple organ dysfunction syndrome (MODS)were compared.Results After treatment,the observation group of NK cells,CD4+/CD8+and CD3+were higher than those before treatment,the differences were statistically significant(P＜0.05).The observation group of NK cells,CD4+/CD8+,CD3+levels were higher than those of the control group after treatment,the differences were statistically significant(P＜0.05).The incidence of MODS in the observation group was 10.00%(4/40)and the mortality rate was 5.00%(2/40),the incidences of MODS in the control group was 35.00%(14/40)and the mortality rate was 22.50%(9/40),the incidence of MODS and mortality in the observation group were both higher than those in the control group,the differences were statistically significant(P＜0.05).Conclusion The early application of Shenfu Injection for patients with severe trauma is of great significance.It can effectively improve the immune function and improve the prognosis.It is worth popularizing. 2018 Vol. 25 (10): 154-156 [Abstract] ( 130 ) HTML (30 KB)  PDF (2211 KB)  ( 32 ) 157 The clinical analyzing of treatment gastric ulcer with gastrorrhagia by Sucralfate combined with Omeprazole ZENG Qing-zhou;ZHANG Xiao-yan Objective To clinical effect of treatment gastric ulcer with gastrorrhagia by Sucralfate combined with Omeprazole.Methods A total of 80 patients of gastric ulcer with gastrorrhagia treated in our hospital from February 2016 to March 2017 were selected as subjects and divided into control group (40 cases)and observation group(40 cases)by different treatment method.The patients in the control group were treated with Omeprazole alone,and the patients in the observation group were treated with Sucralfate combined with Omeprazole.The hematemesis stop time,stool OB test negative time,abdominal pain disappeared time,the incidence of adverse reactions and the total effective rate of two group were compared.Results The hematemesis stop time([1.7±0.2]d),stool OB test negative time([4.6±1.2]d)and abdominal pain disappeared time([2.2±0.4]d)of observation group were shorter than the control group([2.3±0.4],[6.5±1.3],[3.6±0.5]d),and the differences were statistically significant(P＜0.05).The incidence of adverse reactions in the observation group(7.5%)was lower than that in the control group(25.0%),and the total effective rate(95.0%)was higher than the control group (80.0%),the differences were statistically significant(P＜0.05).Conclusion The clinical symptoms improve time is shorten,the clinical effect is obviously,adverse reactions are little of gastric ulcer with gastrorrhagia patients treated by Sucralfate combined with Omeprazole.It is worth to be used. 2018 Vol. 25 (10): 157-159 [Abstract] ( 167 ) HTML (28 KB)  PDF (2222 KB)  ( 32 ) 160 Effect observation of Maxingshigan Decoction and acupoint application treating senile bronchial pneumonia YANG Yu-lan Objective To explore the clinical effect of Maxingshigan Decoction combined acupoint application treating senile bronchial pneumonia.Methods Seventy-eight patients with senile bronchial pneumonia treated in our department from January 2015 to June 2016 were selected,and they were randomly divided into the two groups,there were 39 cases in each group.The control group received routine treatment of western medicine,while the observation group received Maxingshigan decoction and acupoint application treatment.The clinical curative effect,symptom relief time,lung function indexes and inflammatory factor indexes were compared between the two groups.Results The total effective rate of the observation group was 94.87%,which was higher than that of the control group(71.79%),and the difference was statistically significant(P＜0.05).The remission time of all the symptoms in the observation group was shorter than thaose in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in the indexes of pulmonary function and inflammatory factors indexes between the two groups(P＞0.05),after treatment,the index of lung function indexes in the observation group were higher than those of the control group,and the index of inflammatory factor indexes were lower than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion In elderly patients with bronchial pneumonia,Maxingshigan Decoction and acupoint application combined treatment is effective,it can effectively relieve symptoms,improve lung function and inhibit the inflammatory reaction in the body. 2018 Vol. 25 (10): 160-162 [Abstract] ( 147 ) HTML (29 KB)  PDF (2259 KB)  ( 34 ) 163 Study of intervention role of Pinggan Qianyang Prescription for footbathing on insomnia caused by hypertension LI Jing-qiu Objective To observe the intervention role of Pinggan Qianyang Prescription for foot-bathing on insomnia caused by hypertension type excessive rising of liver-yang.Methods Sixty-two patients with insomnia caused by hypertension type excessive rising of liver-yang treated in our hospital from March 2014 to March 2016 were selected as object and they were divided into the control group(31 cases)and experimental group(31 cases)according to the random grouping method.The control group was given with conventional treatments,while the treatment group was given conventional treatments plusing Pinggan Qianyang Prescription for foot-bathing before going to bed.The sleep condition was compared between the two groups before and after intervention,and the SPIEGEL score was used in the sleep evaluation.ResultsAfter intervention,SPIEGEL score of the two groups were all improved compared with those before intervention,and the difference was statistically significant(P＜0.05).SPIEGEL score of patients in the experimental group was(8.19±4.39)points,which was significantly lower than that of the control group([12.19±5.94]points),and the difference was statistically significant(P＜0.05).Conclution Pinggan Qianyang Prescription for foot-bathing can improve the sleeping quality in patients with insomnia caused by hypertension type excessive rising of liver-yang. 2018 Vol. 25 (10): 163-165 [Abstract] ( 136 ) HTML (29 KB)  PDF (2270 KB)  ( 38 ) 166 One case report and literature review of surgical treatment of Langerhans cell histiocytosis in the adult lumbar spine WANG Huan;CAI Zhong-min;SHANG Ping;LONG Li-yan;WANG Qi;JIANG Huan-chang Langerhans cell histiocytosis (LCH)is a rare disease caused by abnormal hyperplasia of Langerhans cells.The skeletal system is often involved.The radiological findings usually resemble vertebral tumors and tuberculosis,final diagnosis needs to be examined by pathology,and treatment methods are usually varied,surgical treatment can achieve good results.One case of LCH in the adult lumbar spine was cured with surgery,and the literatures related to this disease were searched.To investigate the diagnosis,clinical features and therapy of LCH in the adult lumbar spineand improve the understanding of LCH. 2018 Vol. 25 (10): 166-168 [Abstract] ( 155 ) HTML (26 KB)  PDF (2663 KB)  ( 34 ) 169 Clinical application of comfortable nursing interventions in the continuous gastrointestinal decompression for severe pancreatitis patients GU Gui-hua;ZHANG Xiong-wen Objective To analyze the clinical effect of comfortable nursing interventions in the continuous gastrointestinal decompression for severe pancreatitis patients.Methods A total of 54 patients with severe pancreatitis treated from January 2015 to October 2017 in our hospital were selected.The subjects were randomly divided into study group and control group,27 cases in each group.The study groups was adopted the comfortable nursing interventions and the control group was adopted conventional nursing care,respectively.The clinical effect was observed between two groups.Results Before intervention,the comfort level for two groups was not significantly different(P＞0.05);after 3 d and 1 week of intervention,the comfort scores for study group were significantly higher than that in the control group (P＜0.05);before intervention,the POMS points for two groups were not significantly different(P＞0.05);after intervention,the scores of tension,anger,fatigue,depression and confusion for study group were significantly lower than that in the control group (P＜0.05);the scores of energy and individual emotions for study group were significantly higher than that in the control group,the differences were statistically significant(P＜0.05).Conclusion The comfortable nursing intervention has an obvious effect in the continuous gastrointestinal decompression,increases their comfort level,maintains the favorable doctor-patient relationship and improves the clinical prognosis. 2018 Vol. 25 (10): 169-171 [Abstract] ( 136 ) HTML (27 KB)  PDF (2288 KB)  ( 30 ) 172 Application effect of visual health education in the nursing of patients with chronic obstructive pulmonary disease at stable stage LIU Long-ying;PENG Hui-qun;JIANG Ling Objective To analyze the effect of visual health education in the nursing of patients with chronic obstructive pulmonary disease(COPD)in stable period.Methods A total of 120 patients with COPD from July 2016 to June 2017 in our hospital were divided into the observation group and the control group according to the random number table method,60 cases in each group.The normal health education was carried out in the control group,and the visual health education was carried out in the observation group.The health knowledge of the two groups and the lung function and quality of life before and after nursing were compared.Results The good rate of health knowledge in the observation group was significantly higher than that of the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the scores of lung function and quality of life between the two groups before nursing(P＞0.05).After nursing,The FEV1,FVC,PEF and FEV1/FVC in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P＜0.05).The scores of respiratory symptoms,disease influence and activity ability of the observation group were significantly lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Visual health education can effectively improve the cognition of patients with COPD in the stable period,and improve the lung function and quality of life. 2018 Vol. 25 (10): 172-175 [Abstract] ( 157 ) HTML (31 KB)  PDF (2318 KB)  ( 34 ) 176 The influence of accompany emotional nursing on depression in elderly stroke patients SU Qiao-dan;YU Yang;HUANG Man-li;HOU Zheng-ting Objective To study the influence of accompany emotional nursing on depression,and to provide theoretical basis for reducing the prevalence of post-stroke depression.Methods 112 elderly stroke patients were chosed as the research object in our hospital from June 2016 to June 2017.They were randomly divided into study group and control group,according to random number table method,and there were 56 cases in each group.Patients in the control group were treated with routine treatment and care.Besides the routine treatment and care,accompany emotional nursing intervention were given to the study group.Self-rating depression scale(SDS)was used to assess patient′s depression.Trait coping styles questionnaire(TCSQ)was used to evaluate the response of patients.Results There was no statistically significant difference between SDS scores in two groups before intervention(P＞0.05).The SDS score in study groups after intervention was statistically significant(P＜0.05).The incidence of post-stroke depression in study group was lower than that in the control group and was statistically significant after intervention(P＜0.05).The positive coping dimension and negative coping dimension score of TCSQ scale in study groups was lower than that in the control group and was statistically significant after intervention(P＜0.05).Conclusion Accompany emotional nursing can reduce the occurrence of depression in elderly patients with stroke,and help them to adopt a positive coping style to face the disease. 2018 Vol. 25 (10): 176-178 [Abstract] ( 153 ) HTML (26 KB)  PDF (2295 KB)  ( 33 ) 179 Influence study of high-quality nursing mode-guided nursing intervention on fistula maintenance of in maintaining hemodialysis patients ZHANG Hui-hua Objective To study the clinical effect of high-quality nursing intervention in maintenance hemodialysis patients during treatment to maintain the state of arteriovenous fistula.Methods A total of 104 patients undergoing maintenance hemodialysis in our hospital from October 2015 to October 2017 were randomly divided into control group and observation group,52 cases in each group.In the control group,routine blood purification treatment and care during dialysis was used,while in the observation group,high quality nursing intervention during dialysis was adopted.The rate of arteriovenous fistulas remaining intact during treatment,rate of related complications,satisfaction on clinical nursing during treatment,the total time of hemodialysis,and improvement of quality of life before and after the intervention between the two groups were compared.Results In comparison of the of cases of rate arteriovenous fistula remaining in good condition during the treatment,there was a significant difference between the two groups,with a better result in the observation group(P＜0.05).The related-complications rate in the observation group was lower compared with that in the control group with a significant difference(P＜0.05).The satisfaction on clinical nursing in maintenance hemodialysis in the observation group was higher than that of the control group with a statistical difference(P＜0.05).The total duration of treatment in the observation group was shorter compared with that in the control group with a significant difference(P＜0.05).On the improvement of quality of life score before and after the intervention,there was a significant difference between the two groups,with a better result in the observation group(P＜0.05).Conclusion Patients with maintenance hemodialysis receiving high quality nursing intervention during treatment can maintain the state of arteriovenous fistulas and keep them in good condition all the time,reduce the related complications,shorten the treatment time,ameliorate patient′s quality of life,and fundamentally improve nursing satisfaction. 2018 Vol. 25 (10): 179-181 [Abstract] ( 125 ) HTML (28 KB)  PDF (2280 KB)  ( 37 ) 182 Application effect of auricular point buried beans combined with psychological intervention in the treatment of pregnancy exotosis QIU Jiu-lian Objective To explore the clinical effect and nursing effect of auricular point buryied bean combined with psychological intervention in the treatment of pregnancy exotosis.Methods The clinical data of 106 patients with vomiting of pregnancy treated in our hospital from July 2016 to July 2017 were observed and analyzed.They were divided into two groups according to difference treatment methods,53 cases in each group.The control group and the observation group were treated with psychological intervention.On the basis of this,the observation group was treated with Auricular point buried beans therapy.The clinical effect and nursing effect of the two groups were compared.Results The clinical effect of the two groups was compared,the total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Before treatment,the symptom score of the observation group was slightly lower than that of the control group,and the difference was not statistically significant(P＞0.05).After treatment,the observation group was significantly lower than the control group,the difference was statistically significant(P＜0.05).Conclusion The Auricular point buried beans combined with psychological intervention has significant effect in the treatment of pregnancy induced vomiting.It can achieve good clinical results and improve nursing satisfaction,which is worthy of promotion. 2018 Vol. 25 (10): 182-184 [Abstract] ( 137 ) HTML (26 KB)  PDF (2279 KB)  ( 29 ) 185 Influence study of TCM nursing intervention combined with high quality nursing on the complication of bedsore in senile patients after pelvic fracture surgeries WAN Man-hua;LYU Xu-ying;ZHONG Zhi-rong Objective To investigate the effect of traditional Chinese medicine (TCM)nursing intervention combined with high-quality nursing on pressure sores in elderly patients after pelvic fracture surgeries.Methods A total of 60 elderly patients with pelvic fractures admitted in our hospital from March 2012 to May 2016 were selected as the research objects.They were evenly divided into two groups according to the sequence of hospital admission.In the reference group，high quality nursing was provided，while in the observation group，TCM nursing combined with high quality nursing was offered.The quality of life，the incidence of complications and nursing satisfaction of the two groups were compared.Results In the observation group，the quality of life and nursing satisfaction were both higher than those of the reference group(P＜0.05).The incidence of complications in the obseration group was lower than that in the reference group，the differences were statistically significant(P＜0.05).Conclusion Combination of TCM nursing and high quality nursing as an intervention for elderly patients undergone pelvic fracture surgeries can effectively reduce the incidence of complications，ameliorate the quality of life of patients，and improve the patient′s satisfaction on nursing service. 2018 Vol. 25 (10): 185-187 [Abstract] ( 152 ) HTML (27 KB)  PDF (2301 KB)  ( 32 ) 188 Effect of collaborative care nursing on rehabilitation training of swallowing disorder after stroke HE Li-ming;LIANG Wei-rong;XIAO Peng;WANG Yu-long Objective To explore the role of collaborative care nursing (CCM)in rehabilitation training for post-stroke dysphagia (DSA)and provide a reliable basis for clinical.Methods A total of 98 patients with DSA were selected from March 2014 to April 2017.The patients were randomly divided into experimental group and reference group,49 cases in each group.The two groups were treated with routine therapy.Patients of the experimental group was given CCM mode on the basis of the reference group.The degree of dysphagia,clinical efficacy and satisfaction of the two groups before and after treatment were compared.Results After intervention,the total effective rate of the experimental group was 95.92%,which was higher than 81.63%of the reference group,the difference was statistically significant(P＜0.05).Before intervention,the scores of dysphagia in two groups of patients were compared,the difference was not statistically significant(P＞0.05).The score of dysphagia in experimental group after intervention was(2.25±0.87)point,which was significantly lower than that of the reference group([4.31±0.64]point),the difference was statistically significant(P＜0.05).The satisfaction rate of experimental group was 87.76%,which was higher than that of reference group(63.35%),the difference was statistically significant(P＜0.05).Conclusion CCM nursing model has a good therapeutic effect in DSA rehabilitation training,can improve the daily life ability of patients,improve the swallowing dysfunction of DSA patients,reduce the occurrence of adverse emotions in patients,and should be popularized in clinical treatment. 2018 Vol. 25 (10): 188-190 [Abstract] ( 157 ) HTML (28 KB)  PDF (2316 KB)  ( 29 ) 191 Evaluation of clinical application of PICC in cancer nursing FU Fei-yan Objective To explore the effect of using PICC catheter in tumor care.Methods A total of 68 cancer patients from January 2015 to November 2017 in our department were enrolled.Patients were divided into routine group(n=34)and PICC group（n=34）according to patient medication care in all patients.The patients in the rantine group were used routine medicatiow and nursing,the patients in the PICC group were given PICC medication and nursing care.The differences between the two medication care methods were analyzed.Results The incidence of complications in PICC group was significantly lower than that in the conventional group(2.9%vs.20.6%,P=0.024).The satisfaction rate of patients in PICC group was significantly higher than that in the control group(97.5%vs.76.5%,P=0.012).The catheterization time in PICC group([71.2±8.4]d)was significantly higher than that in routine group([6.8±0.7]d)(P=0.000).After treatment,PICC patients′comfort score([27.5±1.8]points)was significantly higher than that of the control group([21.1±1.6]points)(P=0.000).The score of illness uncertainty in patients with PICC([65.1±7.8]points)was significantly lower than that of the control group([76.5±6.8]points),the differences were statistically significant(P＜0.05).Conclusion The use of PICC catheterization in cancer care is excellent. 2018 Vol. 25 (10): 191-193 [Abstract] ( 127 ) HTML (27 KB)  PDF (2303 KB)  ( 28 ) 194 Clinical effect observation of cognitive behavior nursing and psychological care in patients with phobia HUANG Huan-xin;ZHANG Shao-zhen;QIU Hui-ying;MA Yan-ling Objective To observe the clinical effect of cognitive behavioral nursing and psychological care in patients with phobia.MethodsFrom January 2016 to August 2017,96 phobia patients admitted in our hospital were enrolled.They were divided into control group and observation group with 48 cases in each group according to random number table method.In the control group,routine care was provided,while in the observation group,patients were received with cognitive behavioral nursing and psychological care on the basis of the control group.The clinical care effect was compared by scoring dermatology life quality index (DLQ),self-rating depression scale (SDS)and self-rating anxiety scale(SAS)between the two groups.Results The scores of DLQI,SDS and SAS in the two groups after treatment were lower than those before the nursing,with statistical differences(P＜0.05).The scores of the three indicators after care in the observation group were significantly lower than those in the control group,which differed significantly(P＜0.05).The total effectiveness rate of the observation group was 95.83%,higher than that of the control group accounting for 81.25%,with a significant difference(P＜0.05).ConclusionPsychological care and cognitive behavioral nursing for patients with phobia have a high total effectiveness rate and a good quality of life,and mild emotions such as depression and anxiety. 2018 Vol. 25 (10): 194-196 [Abstract] ( 154 ) HTML (27 KB)  PDF (2311 KB)  ( 29 )

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