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2016 Vol. 23, No. 10
Published: 2016-04-08
 
 
4 GC-ECD testing organochlorine residues in 10 kinds of food and medicine medicinal materials like Angelica sinensis
HE Qing-yan;PI Sheng-ling;XIE Jia-chi;XIA Bo-hou;LI Ya-mei;LIN Li-mei
Objective To explore the residual amount of Organochlorine 666，dichlorodiphenyl trichloroethane and quintozene in 10 kinds of food and medicine medicinal materials like Angelica sinensis，to provide experimental data for the safety evaluate for these food and medicine medicinal materials and to provide further reference for the standard. Methods 30 batches medicinal materials were collected from market and 9 kinds of chlorine pesticide residues were tested by using GC-ECD method.Results The average recovery rate of the methods was 90.97%-103.56%and the RSD was 0.4%-2.7%.Among Angelica sinensis and Codonopsis pilosula that were tested，different levels of organochlorine pesticide residues in them.Conclusion The pesticide residual limitations in food and medicine medicinal materials should be strict controlled.
2016 Vol. 23 (10): 4-7转12 [Abstract] ( 156 ) HTML (51 KB)  PDF  (0 KB)  ( 30 )
8 Experimental study of pathological changes on intestinal tissue in mesenteric venous thrombosis rats
CHEN Jian-li;CHEN Jun-mao;WANG Chang-you;ZHANG Guo-zhi;ZHANG Rui-xing;CUI Ming-xin;CAO Wen-bin
Objective To observe the pathological changes of intestinal tissue in rats with different ranges of mesenteric venous thrombosis.Methods Eighty rats were evenly divided into two groups in random with 40 rats in each group.In group A，inner diameter of intestinal tract at 8 cm in first grade branch of superior mesenteric vein and marginal vein was ligated.In group B，inner diameter at 6 cm was closed.The general condition and condition of abdominal cavity were observed.The pathological changes of intestinal tissue at different time points between the two groups were observed after fetching intestinal tissue sample and HE staining.Results In group A，congestion and edema of intestinal tissue were occurred 3 hours after surgery，and hemorrhagic ascites with hematochezia 8 hours after surgery together with necrosis and falling of mucous tissue in partial region.Necrosis of smooth muscle tissue was developed 24 hours after surgery in partial region，and was worsened 48 hours after surgery.72 hours after surgery，transmural infarct of intestine was presented.In group B，there was congestion and edema of intestinal tissue 3 hours after surgery，and hematochezia and necrosis and falling of mucous tissue in partial region 8 hours after surgery.24 hours after surgery，hemorrhagic ascites was occurred together with necrosis of smooth muscle tissue in partial region.48 hours after surgery，no deterioration was detected on these above mentioned symptoms.The intestinal damage was recovered 72 hours after surgery.Conclusion The wider the range of mesenteric venous thrombosis is，the higher the incidence of intestinal necrosis becomes.Hemorrhagic ascites cannot be considered as a surgical indicator on abdominal laparotomy of mesenteric venous thrombosis. Bloody defecation is an approach to alleviate intestinal congestion due to mesenteric venous thrombosis.Maintenance of completion on intestinal smooth muscle succession plays a key role in prognosis of mesenteric venous thrombosis.
2016 Vol. 23 (10): 8-12 [Abstract] ( 159 ) HTML (71 KB)  PDF  (0 KB)  ( 39 )
13 Application of carbon nanoparticles in the surgery of thyroid carcinoma
FANG Hui;CHEN Xu-wei
At present surgery is the primary mean for thyroid carcinoma，it is crucial for the radical dissection of lymph nodes and the protection of parathyroid.The accurate assessment of cervical lymph node metastasis is helpful for the radical dissection of lymph nodes，the protection of parathyroid gland and its blood supply can avoid the incidence of permanent hypoparathyroidism，both are difficulties in the surgical operation.The dissection range of lymph node is more reasonable and parathyroid glands is more safety following the application of lymphatic tracer.The application of carbon nanoparticles in the surgery of thyroid carcinoma is reviewed based on the relevant literatures published in China and abroad.
2016 Vol. 23 (10): 13-16 [Abstract] ( 159 ) HTML (44 KB)  PDF  (0 KB)  ( 34 )
17 The treatment current situation of perimenopausal uterine fibroids
CHEN Li-juan;LI Cheng-zhi
Fibroid is the most commonly seen benign urogenital tumors for females，which is commonly seen in females in child bearing period.However，studies have demonstrated that the morbidity rate of fibroid is also high in perimenopausal females.Although most of the perimenopausal fibroid will cease growth or even get narrowed along with the reduction of estrogen level，but some untreated perimenopausal fibroid，rather than narrow down，may continue to growth or even turn malignant after entering the menopausal period.This article aims to discuss the necessity of the treatment of perimenopausal fibroid and the selection of therapeutic approaches.
2016 Vol. 23 (10): 17-20 [Abstract] ( 137 ) HTML (54 KB)  PDF  (0 KB)  ( 4 )
21 Comparison of the effects of laparoscopic totally extraperitaneal prosthetic and modified Kugel surgery in the treatment of adult inguinal hernia
HU An-ran;HUANG Ke-chu;WANG Yong-zhong;XU Shu-kai
Objective To compare and study the curative effects of laparoscopic totally extraperitaneal prosthetic （TEP）and modified Kugel surgery in the treatment of adult inguinal hernia.Methods Clinical data of 148 adult patients with inguinal hernia who were admitted to the department of general surgery in our hospital from June 2012 to June 2014 were retrospectively analyzed.All the patients were randomly divided into two groups，with 72 patients in TEP group and 76 patients in the modified Kugel group.Costs of hospitalization，surgery time，postoperative length of stay，lasting time of postoperative incision pain and postoperative complications were compared between the two groups of patients.After 12～24 months of follow-up visit，postoperative relapses were observed.Results The surgeries in the two groups were both successful.The cost of hospitalization in the TEP group was（8564.5±609.5）yuan，and the cost in the modified Kugel group was（6708.5±854.4）yuan.The cost of hospitalization in the TEP group was higher，and the difference was statistically significant（P＜0.01）；in the comparison of postoperative length of stay and lasting time of postoperative incision pain between the two groups，TEP groups were both shorter，and the differences were statistically significant（P＜0.01）.The differences of the comparison of surgery time and postoperative complications such as hematoma or effusion of the scrotum，urinary retention and pain in the patch regions were not statistically significant（P＞0.05）.However，the incidence rate of seroma in the TEP group　（15.3%）was significantly higher than that in the modified Kugel group（2.6%），and the difference was statistically significant（P＜0.01）.There was no relapse in both the two groups after the surgery.Conclusion The total cost of hospitalization in the TEP group is higher than that in the modified Kugel group，but patients receiving TEP have the advantages of fast postoperative recovery，early discharge time，short lasting time of postoperative incision pain.Therefore，TEP is a safe and feasible method.
2016 Vol. 23 (10): 21-23转26 [Abstract] ( 162 ) HTML (41 KB)  PDF  (0 KB)  ( 35 )
24 Observation on effect of closed regative pressure drainage combined with recombinant human epidermal growth factor for external use in the treatment of ulcerative pressure ulcer
WANG Yi-lian
Objective To investigate the effect of closed negative pressure drainage combined with recombinant human epidermal growth factor for exteranl use in the treatment of ulcer.Methods 50 patients with ulcerative bedsore were treated in our hospital from October 2011 to 2012 October were selected and randomly divided into the study group and the control group，the control group patients was adopt closed negative pressure drainage in the treatment of diseases，and research group was took closed negative pressure drainage surgery combined with recombinant human epidermal growth factor for external use solution for disease treatment.The treatment time，debridement and wound infection rate were compared between the two groups.Results The treatment time of the study group was（8.5±1.6）days，shorter than that of the control group（10.6±2.3）days.The effective rate was 100%（25/25），84%（21/25）higher than that of control group　（P＜0.05），which was significantly better than that of control group.Wound infection occurred less，there is no satistically significance（P＞0.05）.Conclusion Ulcerative pressure ulcers in patients taking closed suction drainage joint rhEGF treatment has a good effect，positive clinical significance，worth actively promoted.
2016 Vol. 23 (10): 24-26 [Abstract] ( 162 ) HTML (32 KB)  PDF  (0 KB)  ( 34 )
27 Application value of intraoperative reduction in severe cerebral trauma combined with transtentorial hernia
ANG Shi-wei;LI Feng;HUANG Ding-bo
Objective To discuss the clinical effect of intraoperative reduction on severe cerebral trauma combined with transtentorial hernia.Methods 69 patients with severe cerebral trauma combined with transtentorial hernia treated in our hospital from April 2012 to April 2015 were selected and randomly divided into control group（n=34）and observation group　（n=35）according to admission time.Patients in the control group were treated by craniotomy evacuation of hematoma or decompressive craniectomy，while patients in the observation group were additionally treated by intraoperative reduction.Intracranial pressure and prognosis of both groups after operation were observed.Results There was no significant difference in intracranial pressure between observation group and control group before treatment（P＞0.05）.The intracranial pressure at 1，3 d，and 5 d after operation in the observation group was significantly lower than that of control group　（P＜0.05）.The excellent and good rate of prognosis evaluated by GOS was significantly higher in the observation group（74.3%）than in the control group（50.0%）（P＜0.05）.Mortality was significantly lower in the observation（8.6%）than in the observation group　（29.4%）（P＜0.05）.Conclusion The clinical effect of intraoperative reduction on severe cerebral trauma combined with transtentorial hernia is significant，and it can reduce intracranial pressure with favourable prognosis，thus is worthy to be promoted.
2016 Vol. 23 (10): 27-29 [Abstract] ( 145 ) HTML (34 KB)  PDF  (0 KB)  ( 32 )
30 Correlation research of lesion degree of coronary angiography and cardiovascular risk factor in elderly patients with coronary heart disease
DAI Zheng-dong;WAN Wei;ZHENG Peng
Objective To explore the correlation of lesion degree of coronary angiography and cardiovascular risk factor in elderly patients with coronary heart disease.Methods 4799 elderly patients underwent coronary angiography in our hospital from January 2013 to June 2015 were selected as the research group，3589 cases of them were diagnosed as coronary heart disease，accounted for 74.79%in the total number，included 2188 male patients and 1401 female patients. The correlation of lesion degree of coronary angiography and cardiovascular risk factors in elderly patients was analyzed with one-way analysis of variance and multivariate Logistic regression analysis.Results Single risk factor analysis showed that the age，sex，hypertension，type 2 diabetes，smoking，high TC，high LDL-C and low HDL-C were correlated with the count of coronary artery disease（P＜0.05）.Logistic regression analysis showed that the age，sex，hypertension，type 2 diabetes，high TC and smoking were independent risk factors for coronary heart disease　（P＜0.05），among them，type 2 diabetes was the most significant independent risk factor（P＜0.05）.After grouped by gender，Logistic regression analysis showed that type 2 diabetes remained a significant independent risk factor for coronary heart disease in men　（P＜0.05），type 2 diabetes，hypertension，and smoking were independent risk factors for coronary heart disease in women　（P＜0.05）. Conclusion Type 2 diabetes is a risk factor for cardiovascular disease in elderly patients with coronary heart disease，more prominent in the female group，smoking，hypertension，high TC and age should not be ignored.
2016 Vol. 23 (10): 30-32转35 [Abstract] ( 166 ) HTML (40 KB)  PDF  (0 KB)  ( 35 )
33 Relationship between NT-proBNP and coronary artery lesion degree in patients with coronary heart disease
ZHANG Yong
Objective To explore the relationship between N-terminal pro-brain natriuretic peptide　（NT-proBNP）and coronary artery lesion degree of patients with coronary heart disease.Methods 120 proposed to diagnose coronary heart disease patients from January 2013 to January 2015 were selected as study object.All patients were divided into the positive group（n=70）and the negative group（n=50）according to coronary angiography results.The patients in positive group were divided into the simple branch lesion group　（n=24），the double branch lesion group　（n=25）and the multibranch lesion group　（n=21）according to coronary artery lesion degree.The level of NT-proBNP between coronary angiography positive and negative patients was compared，and the level of NT-proBNP among different coronary artery lesion patients was compared.Results The level of NT-proBNP in the coronary artery lesion positive group was higher than that in the negative group，with significant difference（P＜0.01）.The level of NT-proBNP in the multi-branch lesion group was higher than that in the simple branch lesion group and the double branch lesion group，with significant difference　（P＜0.01）.The level of NT-proBNP in the double lesion group was higher than that in the simple branch lesion group，with significant difference（P＜0.01）.Conclusion After eliminating the factors of heart failure，the level of NT-proBNP in coronary heart disease patients has some correlation with the serve degree of coronary artery lesions，coronary artery lesion is heavier，the higher the level of plasma NT-proBNP.
2016 Vol. 23 (10): 33-35 [Abstract] ( 167 ) HTML (34 KB)  PDF  (0 KB)  ( 4 )
36 Relationship between homocysteine level and the severity degree of coronary artery disease in patients with coronary heart disease
LIN Bin

Objective To explore the relationship between homocysteine（Hcy）level and the severity degree of coronary artery disease in patients with coronary heart disease.Methods 192 patients from January 2013 to January 2014 in our hospital were selected as the research group，160 cases of them diagnosed by coronary angiography were selected as the coronary heart disease group，and 32 patients with normal coronary angiography were selected as the control group.The level of Hcy in different groups was compared.Results The level of Hcy in the coronary heart disease group was higher than that in the control group，with significant difference　（P＜0.01）.The level of Hcy increased with the increased of Gensini score（P＜0.05），and the level of Hcy increased with the increased number of coronary artery lesion.Conclusion The level of serum homocysteine can be used as an indicator to predict the severity degree of coronary artery lesion.
2016 Vol. 23 (10): 36-38 [Abstract] ( 157 ) HTML (40 KB)  PDF  (0 KB)  ( 4 )
39 Expression and its significance of plasma lipoprotein phospholipase A2in patients with cerebral infarction
ZHU Shao-wen;ZHAI Dong-yan;ZHANG Jin-lan;LU Zhan-hong;LI Qiu-xia;YANG Cai-mei;CHEN Ya-wen
Objective To study the level and significance of plasma lipoprotein phospholipase A2（Lp-PLA2）in patients with cerebral infarction.Methods 120 patients with atherosclerotic cerebral infarction during January to December 2015 in neurology department of our hospital were selected into case group，and 120 healthy persons during the same period were randomly selected from medical examination center of our hospital into control group.Lp-PLA2，homocysteine（Hcy），low density lipoprotein cholesterol（LDL-C），fibrinogen（Fib），fasting blood glucose（Glu），and white blood cell （WBC）of the two groups were tested and compared.The subjects of cerebral infarction group were divided into mild，moderate and severe three groups，according to the severity of the disease（according to the National Institutes of Health Stroke Scale score）.The Lp-PLA2levels of the three groups were compared，and the correlations of Lp-PLA2with Hcy，LDL-C，Fib，Glu，and WBC were obtained according to the Spearman′s correlation analysis.Results The levels of Lp-PLA2，LDL-C，Hcy，Fib and WBC in the case group were higher than those in the control group respectively，with statistical significance　（P＜0.05）.Lp-PLA2levels of the mild，moderate and severe groups of cerebral infarction were increased in turn，which were positively correlated with the severity of the disease，with statistical significance　（P＜0.05）.The level of Lp-PLA2was positively correlated with LDL-C level，while it had no correlation with Hcy，Fib，Glu and WBC levels. Conclusion The level of Lp-PLA2reflects the severity of cerebral infarction，thus it can be used as a new method to predict the prognosis of cerebral infarction，and provide guidance information for clinical treatment decision.
2016 Vol. 23 (10): 39-41 [Abstract] ( 171 ) HTML (43 KB)  PDF  (0 KB)  ( 19 )
42 Impact and its related risk factors of transient ischemic attack on secondary cerebral infarction
ZHAN Yuan;ZHANG Yu-ping;WANG Qiang
Objective To explore the impact of transient ischemic attack on secondary cerebral infarction and its related risk factors.Methods 160 TIA patients from April 2013 to March 2015 of our hospital were selected.Patients were divided into cerebral infarction group　（n=59，group A）and non-cerebral infarction group　（n=101，group B）according to whether the development of cerebral infarction.59 cerebral infarction patients without TIA were selected as group C.Pearsonsingle-factor analysis and multi-variate logistic analysis were used in group A and B to study the risk factors that from TIA to cerebral infarction.Degree of nervous functional defects and outcome scale between group A and C were compared.Results Pearsonsingle-factor analysis showed that the difference among age，hypertension history，diabetes history，coronary heart disease history，carotid plaque and hyperhomocysteinemia had statistical significance（P＜0.05）.Multi-variate logistic analysis showed that age，hypertension history，diabetes history and carotid plaque were the risk factors that from TIA to cerebral infarction.Degree of nervous functional defects in group A was less than that in group C　（P＜0.01）and the progress was better than that in group C　（P＜0.01）.Conclusion The risk factors that impact TIA to cerebral infarction are age，hypertension history，diabetes history and carotid plaque.And ischemic tolerance after TIA has neuroprotection effect on subsequent cerebral infarction and can decrease the nervous functional defects degree of cerebral infarction patients.
2016 Vol. 23 (10): 42-44转48 [Abstract] ( 143 ) HTML (39 KB)  PDF  (0 KB)  ( 31 )
45 Rehabilitation effect of community diversity comprehensive mental rehabilitation measures for patients with schizophrenia
GAO Yun;HU Jian-ping;XIE Su-qing
Objective To investigate the effect of community comprehensive mental rehabilitation measures on the rehabilitation of patients with schizophrenia.Methods 200 sufferers with schizophrenia at our area from January 2013 to January 2015 were divided into the observation group and the control group according order to random method，100 cases in each.The control group only received a follow-up assessment to understand the patients′medication and condition changes，not to carry out rehabilitation guidance.The research group was given comprehensive rehabilitation intervention measures，the intervention time was 1 year，and the effect of the two groups were observed.Results The Krawiecka and SDSS scores of the study group were significantly decreased，while the control group were not significantly decreased，SDSS score was significantly increased，there was a trend，there were clear differences in the aspects of observation group and control group　（P＜0.01）；the total score and the factor scores of BPRS in the study group were significantly decreased，compared with before intervention，there were clear differences in the aspects（P＜0.05），the total score of BPRS in the control group was higher than that in the control group，and there was a significant trend，there were clear differences in the aspects（P＜0.05）.Conclusion Community rehabilitation intervention measures to promote the rehabilitation of patients with schizophrenia has a positive effect and the foundation that patients come back to the community.
2016 Vol. 23 (10): 45-48 [Abstract] ( 163 ) HTML (50 KB)  PDF  (0 KB)  ( 33 )
49 Comparison of clinical effect of modified subtemporal approach and frontotemporal cutting the zygomatic arch subtemporal approach on the resection of cavernous sinus tumors
HE Zhi-gang;SU Yu-tao;WANG Xin-liang
Objective To compare the clinical effect of modified subtemporal approach and frontotemporal cutting the zygomatic arch subtemporal approach on the resection of cavernous sinus tumors.Methods 72 patients with cavernous sinus tumors with tumor resection in our hospital from March 2010 to March 2013，were randomly assigned to the observation group（36 patients）and control group（36 patients）via number method.The observation group was given modified subtemporal approach resection，and the control group was given frontotemporal cutting the zygomatic arch subtemporal approach resection.The rate of resection，postoperative complications and long-term effects were compared and observed between the two groups.Results The resection rate in the two groups was not statistically different（P＞0.05）.The incidence rate of disappearance of frontalia and temporal muscle atrophy after the surgery in the observation group was significantly lower than that in the control group；the proportion of better postoperative activity ability in the observation group was significantly higher than that in the control group，and the difference was statistically significant（P＜0.05）；the differences of the proportion of eye muscle functions with level between the observation group and the control group was significantly different（P＜0.05）.Conclusion The resection rate of cavernous sinus tumors with modified subtemporal approach resection is higher，the postoperative complications can be reduced，and postoperative activity ability can be improved.At the same time，patients′eye muscle functions can be significantly improved.The approach is safe and reliable，which is worthy of clinical promotion and application.
2016 Vol. 23 (10): 49-51 [Abstract] ( 157 ) HTML (43 KB)  PDF  (0 KB)  ( 21 )
52 Clinical study of primary headache complicated with anxiety and depression disorder
HOU Jun-xia;YE Lin-feng;LU Guo-yun;LIAO Xin-long;WU Xiao-yang;LU Xiao-li;HUANG Kua-kua
Objective To analyze the incidence of anxiety and depression in the patients with primary headache admitted to the outpatient clinic of neurology and their influencing factors.Methods The patients who were firstly admitted to the outpatient clinic of neurology in our hospital with the complaint of headache from October 2013 to October 2015 were continuously collected.According to the international diagnosis criteria for primary headache，cases of migraine or tension headache were included.All included patients were given cranial CT or MRI first.Afterwards，patients'gender，age，occupation，income，educational background and course of disease were registered，and Hamilton Depression Scale （HAMD）was applied for the determination of anxiety and depression.Results①596 patients with primary headache were collected，among whom 323 patients were complicated with anxiety and depression disorder，with the incidence rate of 54.2%.The incidence rate of anxiety and depression disorder in the patients with migraine was 51.1%，and its incidence rate in the patients with tension headache was 60.4%.The difference between the two was statistically significant （χ2=4.574，P=0.032）.②The incidence rate of anxiety and depression disorder in the patients with primary headache who were female，unemployed，poorly educated，had low income and the course of disease over 1 year was significantly higher than that in male patients，employed patients，well-educated patients，patients with high income and patients with the course of disease≤1 year，the differences were statistically significant（χ2=6.576，P=0.010；χ2=20.579，P=0.001；χ2=5.610，P=0.018；χ2=11.946，P=0.001；χ2=12.571，P=0.000）.Conclusion The patients with primary headache are usually complicated with anxiety and depression.Attention should be paid to complicated symptoms during treatment and diagnosis，especially for female patients，unemployed patients，poorly educated patients，patients with low income and patients with the course of disease over 1 year.
2016 Vol. 23 (10): 52-54转58 [Abstract] ( 145 ) HTML (38 KB)  PDF  (0 KB)  ( 42 )
55 Effect observation of the improved intravenous thrombolytic therapy for acute cerebral infarction with urokinase
YIN Yao-hui;HUANG Shu-yi;SHEN Wei-bing;LU Ping-hua;LU Chao;LIN Jia-qing;YE Shao-hui
Objective To investigate the possibility of the improved intravenous thrombolytic therapy for the acute cerebral infarction with urokinase.Methods 56 cases of patients with acute cerebral infarction from January 2013 to March 2014 were randomly divided into traditional urokinase thrombolysis group　（quick delivery）with 28 cases and improved urokinase thrombolysis group（slow delivery）with 28 cases.The traditional urokinase thrombolysis group was given conventional intravenous thrombolytic therapy with urokinas，and the improved urokinase thrombolysis group was given improved intravenous thrombolytic therapy with urokinase.The clinical effect of two groups were compared.Results NIHSS scores of the treatment group were significantly decreased after using urokinase at 3，7，14，30 d　（P＜0.05）.BI scores of the treatment group were significantly increased after 7，14 d　（P＜0.05）.The total effective rate in the improved urokinase thrombolysis group was 92.86%，which was higher than 82.14%of the traditional urokinase thrombolysis group，and the difference were statistically significant（P＜0.05）.The security was increased significantly in modified urokinase thrombolysis group compared with that in traditional urokinase thrombolysis group.Conclusion The improved intravenous thrombolytic therapy for acute cerebral infarction is a kind of safe and effective method.
2016 Vol. 23 (10): 55-58 [Abstract] ( 154 ) HTML (45 KB)  PDF  (0 KB)  ( 27 )
59 Application of pre-hospital care in patients with acute cerebrovascular disease
HUANG Yong-yi
Objective To explore the application value of pre-hospital care in the patients with acute cerebrovascular disease.Methods 128 patients with acute cerebrovascular disease who were admitted to our hospital from June 2012 to June 2014 were randomly assigned to the experiment group（68 patients，given first aid before admission）and the control group　（60 patients，not given first aid before admission）.Retrospective analysis was applied to comprehensively evaluate the clinical curative effects of two groups of patients 3 months after admission.Results The effective rate of treatment in the experiment group（91.2%）was significantly higher than that of 73.3%in the control group with significant differeace　（P＜0.05）；the score of Barthel index and FMA score in the experiment group and control group were significantly increased compared before admission　（P＜0.05）；the length of stay in the experiment group was significantly shorter than that in the control group（P＜0.01）；the incidence rate of complications in the experiment group（7.4%）was significantly lower than that in the control group（20.0%）（P＜0.05）；the morality rate in the experiment group（2.9%）was significantly lower than that in the control group（13.3%）（P＜0.05）.Conclusion Pre-hospital care is able to effectively improve the clinical curative effects of acute cerebrovascular disease and improve the prognosis，which is of favorable clinical application value.
2016 Vol. 23 (10): 59-61 [Abstract] ( 146 ) HTML (40 KB)  PDF  (0 KB)  ( 31 )
62 Clinical effects of Naloxone combined with Xuesaitong in treating senile cerebral infarction
ZHAO Li-qun;RAO Wang-fu
Objective To explore the clinical effects of Naloxone combined with Xuesaitong in treating senile cerebral infarction.Methods 142 senile cerebral infarction patients from April 2013 to December 2014 of our hospital were selected as study object.Patients were divided into study group　（Naloxone combined with Xuesaitong）and control group （Naloxone）according to the order of admiting.The treatment effect in two groups was compared.Results The total effective rate in study group（98.6%）was obvious higher than that in control group（84.5%），and the difference was statistical significant（P＜0.05）.After treatment，the activities of daily living score in study group　［（80.2±25.7）scores］was higher than that in control group［（62.4±24.8）scores］（P＜0.05），neurological deficit score［（12.3±5.2）scores］was lower than that in control group　［（17.4±5.7）scores］（P＜0.05）；there was no adverse effect during treatment and after tretament in two groups.Conclusion Naloxone combined with Xuesaitong in treating senile cerebral infarction has obvious effects.It can improve activities of daily living and neurological deficit of patients，with little adverse effects and high safety and is worth to popularize and study deeply.
2016 Vol. 23 (10): 62-64 [Abstract] ( 134 ) HTML (41 KB)  PDF  (0 KB)  ( 23 )
65 Impact of different surgical treatment of complex renal calculi patient on postoperative sexual function and quality of life
WAN Fu-qing;WANG Zan-li;FENG Zi-yu;ZHANG Xue-cong
Objective To analyze the impact of different surgical treatment of complex renal calculi patient on postoperative sexual function and quality of life.Methods 162 patients with complex renal calculi in our hospital from January 2012 to April 2015 were selected.All patients were received minimally invasive percutaneous nephrolithotomy treatment（MPCNL group）.The sexual function and quality of life were assessed before and after surgery using sexual function index questionnaire and short-form health survey，respectively.Meanwhile，128 patients with complex renal calculi treated by open operation treatment were selected as control group.The related parameters between two groups were compared.Results Compared with control group，the stone clearance rate of MPCNL group was higher（P＜0.05），the operation time，operation blood loss and complication rate of MPCNL group were lower（P＜0.01）.Followed up from postoperative 3 months and 6 months，the erectile function，orgasm，role-physical，sexual function and quality，sexual satisfaction，role-emotion，metal health were statistically significant than those of control group（P＜0.05）.Conclusion MPCNL in the treatment of complex renal calculi has higher clinical value.The sexual function and quality of life can be improved after operation.
2016 Vol. 23 (10): 65-67 [Abstract] ( 145 ) HTML (40 KB)  PDF  (0 KB)  ( 7 )
68 Application of flexible ureteroscope in the treatment of upper urinary tract calculi
HUANG Nan-ping
Objective To analyze the application effect of flexible ureteroscope in the clinical treatment of upper urinary tract calculi.Methods From January 2014 to May 2015，76 patients with upper urinary tract calculi treated in our hospital were selected.Patients treated by holmium laser lithotripsy under flexible ureteroscope were selected as research group　（n=38）.Patients treated by holmium laser lithotripsy under ureterscopy plus extracorporeal shock-wave lithotripsy were chosen as control group　（n=38）.The clinical efficacy and postoperative complications in the two groups were compared.Results The total clinical therapeutic effective rate in the research group was much higher than that in the control group.Meanwhile，the incidence of complications in the research group was much lower than that in the control group，which was a displayed statistical difference between intra-groups（P＜0.05）.Conclusion In the clinical treatment of upper urinary tract calculi，surgery under flexible ureteroscope can effectively improve clinical efficacy，reduce the occurrence of postoperative complications in safety and efficiency，which has a good clinical application value.
2016 Vol. 23 (10): 68-70 [Abstract] ( 132 ) HTML (38 KB)  PDF  (0 KB)  ( 17 )
71 Effect of bacterial infection stimulation on progression of lupus nephritis
LUAN Jun-jun;XING Guang-qun;LI Yuan
Objective To discuss the effect of bacterial infection stimulation on progression of lupus nephritis.Methods 19 LN patients without bacterial infection treated in our department from December 2012 to December 2014 were selected and divided based on the active levels of disease into the LN onset group　（n=10）and the LN remission group （n=9）.Another 10 healthy volunteers were selected as the control group.Peripheral blood mononuclear cells（PBMC）were extracted，cultivated and stimulated with CpG-ODN.The level of interferon-α　（IFN-α）in serum and supernatant liquid was tested by ELISA.Results①The level of IFN-α was significantly higher in the LN onset group［（1072.87± 530.99）ng/ml］than in the LN remission group［（348.60±190.63）ng/ml，P＜0.01］and the control group［（293.31±214.40）ng/ml，P＜0.01］）.②With the stimulation of CpG-ODN，the PBMC supernatant liquid IFN-α level was significantly higher in the LN remission group［（2616.36±2393.76）ng/ml］than in the LN onset group［（1109.37±396.66）ng/ml，P=0.024］and the control group［（1121.98±370.46）ng/ml，P=0.025］.Conclusion Bacterial infection is an inducing factor of progression of LN.
2016 Vol. 23 (10): 71-73转89 [Abstract] ( 127 ) HTML (42 KB)  PDF  (0 KB)  ( 9 )
74 Comparison of PFNA and DHS in the treatment of elderly patients with intertrochanteric fracture
WU Qi-ming;SUN Ji-kai;TANG Wen-cheng;ZENG Jie-jie;DENG Jian-ping;ZHANG Li;LI Jian-bin;CHENG Xi-hong
Objective To explore the therapeutic effect of applying minimally invasive proximal femoral nail antirotation（PFNA）and internal fixation of dynamic hip screw（DHS）in treating intertrochanteric fracture in the elder.Methods From December 2010 to June 2013，146 medical cases of elderly intertrochanteric fracture treated in our hospital were retrospectively analyzed.According to different internal fixations，they were divided into PFNA group（n=74）and DHS group　（n=72）.The operation time，incision drainage，surgical bleeding，fracture healing time，occurrence of postoperative complications，recovery of hip function，ambulation time after surgery，activities of daily living score and functional score by Harris standard were observed in the two groups.Rasmussen score was used to compare and evaluate movement and touch one month before and after surgery in the two groups.Results All recruited medical cases were successfully finished 2 years follow-up visits.The indexes of operation time，surgical bleeding，ambulation time after surgery，hospital stay，excellent and good rate of Harris score in PFNA group was better than that in DHS group respectively，with statistical differences（P＜0.05）.There was no statistical difference in incision drainage，hemoglobin loss during perioperative period，or fracture healing time（P＞0.05）.After one-month treatment，indexes of movement and touch score was superior to that in DHS group respectively，with statistical differences（P＜0.05）.After surgery，complications including incision nonunion due to infection，nonunion，deep venous thrombosis，coxa vara，and looseness of internal fixation were not presented in the two groups.Conclusion There was no great difference in postoperative function recovery in these two fixation modes，but PFNA therapy catches opportunities in operation time，surgical bleeding，ambulation time after surgery，hospital stay，and postoperative complications in the treatment of elderly intertrochanteric fractures，which is an effective therapeutic method to treat intertrochanteric fractures in the elder in clinic.
2016 Vol. 23 (10): 74-77 [Abstract] ( 142 ) HTML (47 KB)  PDF  (0 KB)  ( 28 )
78 Effect analysis of cervical posterior single-door plus internal fixation of miniature titanium plate in the treatment of multi-segmental cervical spondylosis myelopathy
WU Xiao-hua;ZHANG Xian-yu;ZOU Feng-wen;SHUANG Ou
Objective To explore the clinical effect of cervical posterior single-door plus internal fixation of miniature titanium plate in the treatment of multi-segmental cervical spondylosis myelopathy.Methods From February 2013 to July 2014，67 patients who were diagnosed as multi-segmental cervical spondylosis myelopathy and treated in our hospital were selected as research objects.According to a random number table，they were divided into observation group（n= 33）and control group（n=34）.In the observation group，cervical posterior single-door plus internal fixation of miniature titanium plate was used，while in the control group，traditional expanded forming silk suture internal fixation by cervical posterior single-door was adopted.The time of implementing rehabilitation after surgery，therapeutic effect，and incidence of complications in the two groups were compared.Results The incidence of complications in the observation group was 6.1%，the postoperative rehabilitation time was（16.1±2.2）d，and the total therapeutic effective rate was 97.0%；while in the control group，they were 20.6%，（26.6±6.7）d，and 85.3%，which were displayed statistical differences between the two groups（P＜0.05）.Conclusion Cervical posterior single-door plus internal fixation of miniature titanium plate in the treatment of multi-segmental cervical spondylosis myelopathy can obtain a definite clinical effect，and promote patient′s postoperative rehabilitation exercise at an early stage in high safety.
2016 Vol. 23 (10): 78-80 [Abstract] ( 151 ) HTML (38 KB)  PDF  (0 KB)  ( 30 )
81 Effect comparison of different fixation type in treating thoracolumbar spinal fractures
LIU Xiao-lei;SUN Jing-fu;WU Ren-tao;LI Jin-kun;GUO Wei-hua;LIU Xiao-peng
Objective To explore the effect of different fixation type in treating thoracolumbar spinal fractures.Methods 96 thoracolumbar spinal fractures patients from January to November 2014 of our orthopedics department were selected as study objects and were divided into internal fixation group and internal fixation plused bone grafting group according to the random number table method.Each group was 48 cases.Patients in internal fixation group were given internal transpedicular fixation，and patients in internal fixation plused bone grafting group were given internal transpedicular fixation combined with bone grafting between vertebral plate.Good rate of spinal cord nerve function，convex Cobb angle before and after treatment，intraspinal space occupied，anterior vertebral height in two groups were compared. Results After treatment，both of convex Cobb angle and intraspinal space occupied obvious decreased between two groups and anterior vertebral height obvious increased，and the improvement degree in internal fixation plused bone grafting group was more and the difference between two groups was statistical significance（P＜0.05）.The good rate of spinal cord nerve function in internal fixation plused bone grafting group was obvious higher than that in the internal fixation group and the difference between two groups was staitistical significance（P＜0.05）.Conclusion Internal transpedicular fixation combined with bone grafting between vertebral plate has definite effect in treating thoracolumbar spinal fractures.It can improve spinal cord nerve function，decrease convex Cobb angle and intraspinal space occupied and enhance anterior vertebral height.It is worth to popularize.
2016 Vol. 23 (10): 81-83 [Abstract] ( 133 ) HTML (38 KB)  PDF  (0 KB)  ( 36 )
84 Effectobservation　oftotalhip　replacementin　the　treatmentof coxarthropathy
CHEN Bin;ZHANG Yuan-tao;CHEN You-bin;LIN Hai-ming;LUO Shao-wei
Objective To analyze the clinical effect of total hip replacement in the treatment of coxarthropathy.Methods Seventy-six patients with coxarthropathy undergone total hip replacement ranging from 2009 to 2013 in our hospital were selected as research objects and classified into observation group.Another group of 50 patients with coxarthropathy who were applied with regular treatment was selected as control group.The improvement of hip joint function and pain degree after therapy in both groups were compared.At the same time，the occurrence of postoperative complications in the observation group was understood.Results The excellent and good rates of hip joint function improvement after therapy in the observation group and control group was 93.98%，49.09%respectively.The pain by visual analogue scale（VAS）score between two groups was（2.8±1.0）points and（7.3±2.1）points，and the Harris score between the two groups was（88.3±4.5）points and（65.1±2.9）points in turn.The improvement of indexes in the observation group after comparison was significantly better than that in the control group，with statistical differences（P＜0.05）.During the follow-up period，no hip dislocation，nerve injury，infection，screw loosening and other complications occurred in the observation group.Conclusion Total hip replacement can obtain a remarkable effect in the treatment of coxarthropathy.It can decrease patient′s pain degree，display a favorable recovery effect of hip joint function after surgery，and has a low incidence of complications with an optimal effect.
2016 Vol. 23 (10): 84-86 [Abstract] ( 135 ) HTML (41 KB)  PDF  (0 KB)  ( 38 )
87 Influence of dynamic hip screw and proximal femoral nail anti-rotation on amount of bleeding during perioperative period in the elder suffering from intertrochanteric fracture
ZHANG Shi-hao;CAO Xiang-yu;MIAO Wei-dong;WANG Jun-chen;YANG Yu-shan
Objective To analyze the amount of bleeding during perioperative period due to intertrochanteric fracture in elderly patients treated by dynamic hip screw（DHS）and proximal femoral nail anti-rotation（PFNA）.Methods From July 2009 to July 2015，data from 86 patients during follow-up visits were retrospectively analyzed and divided into DHS group and PFNA group according to the type of surgery.The amount of bleeding during surgery as well as obvious and hidden blood loss after surgery between the two groups was compared.Results The intraoperative amount of bleeding in DHS group and PFNA group was　（162.5±30.6）ml and　（133.6±41.5）ml respectively.The postoperative obvious blood loss in the two groups was（215.7±46.8）ml and（326.9±55.2）ml and the hidden blood loss after surgery in both groups was（426.7±46.8）ml and　（596.9±55.2）ml.The indexes mentioned above were all displayed statistical differences（P＜0.05）.Conclusion Compared with DHS，intertrochanteric fracture treated by PFNA has small trauma and little blood loss，but larger obvious and hidden amount of bleeding after surgery，which should be paid attention.
2016 Vol. 23 (10): 87-89 [Abstract] ( 123 ) HTML (35 KB)  PDF  (0 KB)  ( 31 )
90 Application effect observation of small splint for external fixation and plate-screw for internal fixation in the treatment of type C fracture of distal radius
XIAO Jing
Objective To compare the application effect of small splint for external fixation and plate-screw for internal fixation in the treatment of type C fracture of distal radius.Methods From September 2013 to September 2015，91 patients suffering from type C fracture of distal radius admitted into our hospital were selected.They were randomly divided into control group and observation group according to the time of admission.In the control group，external fixation of small splint was used，while in the observation group，plate-screw for internal fixation was applied.Dienst wrist joint function，measurement index by X-ray，and incidence of complications in the two groups were compared.Results The excellent and good rate of function of wrist joint in the observation group was 69.6%，much higher than that in the control group accounting for 42.2%（P＜0.05）.After treatment，palmar angle and ulnar deviation in the observation group was larger than that in the control group respectively，and the length of shortening was shorter than that in the control group （P＜0.05）.In the observation group，the incidence of complications was 4.3%，much lower than 17.8%in the control group （P＜0.05）.Conclusion Plate-screw for internal fixation can obtain a better therapeutic effect on treating type C fracture of distal radius compared with external fixation of small splint.It can effectively improve function of wrist joint and recovery of bone fracture in safe and reliable，which is worthy of extension and application in clinic.
2016 Vol. 23 (10): 90-92 [Abstract] ( 114 ) HTML (39 KB)  PDF  (0 KB)  ( 36 )
93 Clinical effect of femoral neck locking plate and cannulated screws in the treatment of femoral neck fracture
HU Tao;YUAN Fu;KE Xin;HE Dao-hui;RONG Jian-xin;LIANG Qing-huai
Objective To compare the efficacy of proximal femoral cannulate screw locking plate（PF）and cannulate screw（CS）in the treatment of patients with femoral neck fracture.Methods 100 patients with femoral neck fractures in our hospital from February 2011 to February 2014 were retrospectively analyzed.The patients were randomly divided into CS group（n=50）and PF group（n=50）.The operation time，blood losing，and immediate and long-term Harris hip scoreand were recorded.The time of fracture healing，functional recovery，and complications were observed.Statistical analysis was performed.All the patients were followed up for 18 months.Results The operative time of proximal femoral cannulate screw locking plate versus cannulate screw was respectively（58.39±14.7），（55.68±15.9）min（P＜0.05）；Bloold loss was（278.25±12.8），（276.78±19.2）ml，with statistical difference（P＜0.05）；The hospital stay was respectively（10.27±2.2），（13.48±1.8）days，with statistical difference（P＜0.05）；Fracture healing time was respectively（14.8±4.8），（16.5±3.1）weeks，with statistical difference（P＜0.05）；The short terms of Harris score was respectively（80.65±10.67），（75.03±14.15）points，with statistical difference（P＜0.05），the long terms of Harris score was respectively（89.34±7.84），（88.26±8.85）points.the complication rate was6%（3/50），12%（6/50）.Conclusion Compared with the dy cannulate screw，proximal femoral cannulate screw locking plate in treatment of femoral neck fracture can obtain shorter hospital stay，shorter fracture healing time and short term Harris score.
2016 Vol. 23 (10): 93-95转98 [Abstract] ( 134 ) HTML (42 KB)  PDF  (0 KB)  ( 39 )
96 Clinical effect of modified lateral approach locking compression plate internal fixation in the treatment of calcaneal fractures
WEN Zi-huan;QIU Qing-jun;YU Chun-fu
Objective To compare the clinical efficacy of locking compression plate internal fixation with modified lateral approach and conventional lateral approach in the treatment of calcaneal fractures.Methods 68 patients（80 feet）with calcaneal fractures in our hospital from February 2013 to February 2015 were randomly divided into observation group（44 feet）and control group（36 feet），the observation group was treated with modified lateral approach locking compression plate internal fixation，the control group was treated with conventional lateral approach locking compression plate internal fixation，the complications and AOFAS score excellent rate of two groups were compared.Results The postoperative complication rate of the observation group was 4.5%，which was significantly lower than 16.7%in the control group（P＜0.05）.The excellent and good rate of the observation group AOFAS score was 95.4%，the control group was 77.8%，the difference between two groups was statistically significant（P＜0.05）.Conclusion Locking compression plate internal fixation with modified lateral approach in the treatment of calcaneal fractures can improve the operation effect，reduce the incidence of postoperative complications and promote the recovery of ankle function after surgery.It is worth to be popularized in clinic.
2016 Vol. 23 (10): 96-98 [Abstract] ( 125 ) HTML (36 KB)  PDF  (0 KB)  ( 29 )
99 Comparison of clinical effect of external fixation and percutaneous minimally invasive plate fixation in the treatment of tibial and fibula fractures
LIU Cheng-tao;ZHAO Jin-yang;WANG Xiao-guang;TANG Hao
Objective To compare the clinical curative efficacy and safety of external fixation and percutaneous minimally invasive plate fixation in the treatment of tibial and fibula fractures.Methods 100 patients with open tibiofibular fractures who were treated in our hospital from January 2010 to June 2014 were selected.According to the random number table method，they were divided into minimally invasive by percutaneous plate osteosynthesis group（group A）and external fixator group（group B），with 50 patients in each group.Group A were done minimally invasive per cutaneous plate osteosynthesis，and group B were done external fixation，the operation indicators（operation time，blood loss），postoperative indicators（swelling fade and fracture healing time），the occurring situation of related complications（wound infection，edema，bone is not even，osteomyelitis，nerve injury）and the clinical efficacy were compared between the two groups.Results The operation time and fracture healing time in group B was significantly longer than that of group A respectively（P＜0.05）.The occurring incidence of incision infection，edema，bone nonunion，osteomyelitis，nerve injury and total complication incidence had no significant difference between the two groups（P＞0.05）.The clinical efficacy at last follow-up of group A was significantly better than that in group B（P＜0.05），and the excellent rate in group A was significantly higher than that in group B（P＜0.05）.Conclusion The clinical efficacy of treating tibial and fibula fractures by minimally invasive percutaneous plate osteosynthesis is slightly better than that by fixed bracket operation，it can shorten operation time and fracture healing time，but external fixation can reduce the incidence of infection.
2016 Vol. 23 (10): 99-101转104 [Abstract] ( 118 ) HTML (42 KB)  PDF  (0 KB)  ( 23 )
102 Clinical effect of Kirschner wire and hollow screw internal fixation technique in treating Lisfranc joint injury
KANG Bo
Objective To research the effect of application Kirschner wire and hollow screw internal fixation technique in treating Lisfranc joint injury.Methods 36 Lisfranc joint injury patients from January 2010 to January 2015 of our hospital were randomly divided into control group and treatment group.Each group was 18 cases.Patients in control group were treated by Kirschner wire for internal fixation and patients in treatment group were treated by hollow screw internal fixation.Postoperative foot function was evaluated by using foot score standard in AOFAS.Results The treatment good rate in hollow screw technique treatment group was 88.9%，the foot joint function score before and after operation was respectively　（42.06±6.13）and　（83.58±5.32）points；The treatment good rate in Kirschner wire technique treatment group was 72.2%，the foot joint function score before and after operation was respectively　（41.18±5.06）and （65.58±6.62）points.The treatment effects and foot joint function score in treatment group was obvious better than that of control group respectively，with statistical difference　（P＜0.05）.Conclusion Hollow screw internal fixation technique has obvious effects in Lisfranc joint injury patients.
2016 Vol. 23 (10): 102-104 [Abstract] ( 133 ) HTML (39 KB)  PDF  (0 KB)  ( 21 )
105 Effect observation of the use of levonorgestrel-releasing intrauterine system in the treatment of recurrence of endometriosis after consolidation of conservative surgery combined with drug
WU Hong-juan;LIU Guang-zhen;KONG Min-li
Objective To explore the application effect of levonorgestrel-releasing intrauterine system　（LNG-IUS）in patients with recurrent endometriosis after treatment of conservative operation combined with drug.Methods 68 patients with recurrent endometriosis after treatment of conservative operation combined with drug in our hospital from May 2011 to July 2014 were selected as the research group，all patients were given LNG-IUS for treatment and followed up for 12 months，the therapeutic effect was observed.Results The score of VAS，the level of serum CA125 at 3，6，12 months after placement of LNG-IUS was lower than that before placement of LNG-IUS，the level of hemoglobin at 3，6，12 months after placement of LNG-IUS was higher than that before placement of LNG-IUS，with significant difference　（P＜0.05）.The volume of pelvic mass at 6，12 months after placement of LNG-IUS was less than that before placement of LNG-IUS，with significant difference（P＜0.05）.After placement of LNG-IUS，with the increase in placement time，the endometrial thickness were gradually thinning，menstrual volume was gradually reduced，compared with the before placement，the difference was statistically significant（P＜0.05）.The incidence rate of intermenstrual bleeding after treatment of LNG-IUS at 3 months was 66.2%.The incidence rate of adverse reaction such as bearing-down pain，intermenstrual bleeding，and facial pigmentation were gradually reduced along time，the difference was statistically significant（P＜0.05）.The incidence rate of amenorrhoea and LNG-IUS fall-off was low，there was no significant difference in different time periods（P＞0.05）.Conclusion LNG-IUS has favorable effect in patients with postoperative recurrent endometriosis，it is worthy of clinical promotion and application.
2016 Vol. 23 (10): 105-107 [Abstract] ( 103 ) HTML (40 KB)  PDF  (0 KB)  ( 33 )
108 Influence of family planning service after artificial abortion on contraceptive measure
KONG Hai-yan;XIE Qiu-mei;DUAN Qian
Objective To explore the influence of family planning service after artificial abortion on contraceptive measure.Methods 1000 female patients underwent artificial abortion in our hospital from January 2013 to January 2015 were selected as the research object，500 patients received family planning service after operation were selected as the observation group，and the other 500 patients refused family panning service were selected as the control group.Patients in both groups were followed up at 6 months after artificial abortion to explore the awareness rate of contraceptive knowledge，satisfaction rate of the intervention，the rate of unplanned pregnancy and the condition of repeated artificial abortion.Results The score of contraceptive knowledge after intervention in the observation group was higher than that in the control group，with significant difference　（P＜0.05）.The rate of unplanned pregnancy and repeated artificial abortion in the observation group was lower than that in the control group，with significant difference（P＜0.05）.The satisfaction rate of intervention in the observation group was higher than that in the control group，with significant difference （P＜0.05）.Conclusion Family planning service intervention after artificial abortion can effectively improve the patient′s contraceptive knowledge score，the effect is significant，it is worthy of clinical promotion and application.
2016 Vol. 23 (10): 108-110 [Abstract] ( 124 ) HTML (40 KB)  PDF  (0 KB)  ( 41 )
111 Influence of controlling state of pregnancy complicated with hyperthyroidism on pregnancy outcome
XU Lei
Objective To explore the influence of controlling state of pregnancy complicated with hyperthyroidism on pregnancy outcome.Methods 113 pregnant women with hyperthyroidism in our hospital from January 2014 to June 2015 were selected and divided into the control group　（48 cases）and the oberservation group　（65 cases）according to the wishes of the pregnant women.The control group was not given intervention measure，the treatment group was treated with oral methimazole tablets.The pregnancy outcome and neonatal thyroid hormone level of the two groups was compared.Results The amount of postpartum hemorrhage in the observation group was less than that in the control group，the neonatal Apgar score in the observation group was higher than that in the control group，with significant difference （P＜0.05）.The puerperal infection rate of the observation group was 5.38%，which was lower than 17.71%of the control group，with significant difference　（P=0.003）.The level of T3，T4，FT3，FT4and TSH of newborn in the observation group was lower than that in the control group，with significant difference（P＜0.05）.Conclusion Monitoring early pregnancy thyroid function，early intervention is helpful to improve pregnancy outcome，and no significant side effects on the patients and the fetus，it is worthy of clinical promotion and application.
2016 Vol. 23 (10): 111-113 [Abstract] ( 113 ) HTML (36 KB)  PDF  (0 KB)  ( 19 )
114 Effect analysis of lymphocyte immune actively combined with progestin in the treatment of unexplained recurrent spontaneous abortion
GAO Yuan;SHEN Yu-qing;ZHENG Liang-yu
Objective To explore the effect of lymphocyte immune actively combined with progestin in the treatment of unexplained recurrent spontaneous abortion.Methods 72 cases of unexplained recurrent spontaneous abortion from September 2014 to September 2015 in our hospital were selected and divided into the control group　（32 cases）and the combination treatment group　（40 cases）according to different treatment methods.The control group was not given any treatment before pregnancy，intramuscular injection of human chorionic gonadotropin was given after pregnancy.In addition，intramuscular injection of 40 mg progestin in every day，the combination treatment group was given lymphocyte immune actively combined with progestin.The level of IFN-γ and IL-4 before and after treatment in the two groups was compared，and the pregnancy success rate and abortion rate in the two groups was compared.Results The level of IFN-γ after treatment in the combination treatment group was lower than that before treatment and in the control group after treatment，the level of IL-4 after treatment in the combination treatment group was higher than that before treatment and in the control group after treatment，with significant difference　（P＜0.05）.The pregnancy success rate in the combination treatment group was higher than that in the control group，the abortion rate in the combination treatment group was lower than that in the control group，with significant difference（P＜0.05）.Conclusion The effect of lymphocyte immune actively combined with progestin in the treatment of unexplained recurrent spontaneous abortion is significant，it is worthy of clinical promotion and application.
2016 Vol. 23 (10): 114-116 [Abstract] ( 147 ) HTML (35 KB)  PDF  (0 KB)  ( 44 )
117 Imfluence study of electric coagulation hemostasis and suture hemostasis in laparoscopic ovarian cyst removal on ovarian function
LUO Fang
Objective To explore the influence of electric coagulation hemostasis and suture hemostasis in laparoscopic ovarian cyst removal on ovarian function.Methods 110 patients underwent ovarian cyst removal under laparoscope from January 2014 to May in our hospital were selected and randomly divided into group A and group B，55 cases in each group.Group A was given electric coagulation hemostasis，group B was given suture hemostasis.The level of hormone at preoperative，1 month，3 months and 6 months after operation was compared，the ovarian function in the two groups before and after operation was compared.Results The level of E2，FO at 1 month and 3 months after operation in the two groups was lower than that before operation，the level of LH，FSH at 1 month and 3 months after operation in the two groups was higher than that before operation，with significant difference（P＜0.05）.The level of E2，FO at 1 month and 3 months after operation in group A was lower than that in group B，the level of LH，FSH at 1 month and 3 months after operation in group A was higher than that in group B，with significant difference　（P＜0.05）.There was no significant difference in the condition of ovarian function at 6 months after operation between the two groups　（P＜0.05）.Conclusion Using suture hemostasis in ovarian cyst removal under laparoscope can reduce the influence on patients′s ovarian function，which is helpful to the recovery of postoperative ovarian function，it is worthy of clinical promotion and application.
2016 Vol. 23 (10): 117-119 [Abstract] ( 116 ) HTML (39 KB)  PDF  (0 KB)  ( 34 )
120 Application value of mean corpuscular volume determination in screening of thalassemia in pre-pregnancy physical examination
DUAN Fa-hong
Objective To explore the application value of mean corpuscular volume　（MCV）determination in screening of thalassemia in pre-pregnancy physical examination.Methods 345 patients with thalassemia from September 2012 to May 2015 of obstetric outpatient and internal medicine department in our hospital were selected as study object，136 cases were α thalassemia patients，202 cases were β thalassemia patients，and 7 cases were α and β recombinaison thalassemia patients.Automatic blood cell analyzer was used to detect the MCV.The accuracy of MCV in thalassemia patients and detection rate of each type thalassemia patients were analyzed.Results The accuracy of MCV determination in thalassemia was 92.75%.The detection rate of α thalassemia patients was 92.65%，the detection rate of β thalassemia patients was 92.57%and the detection rate of α and β recombinaison thalassemia patients was 100.00%.Conclusion The application value of MCV determination in screening of thalassemia in pre-pregnancy physical examination is high，which is an effective index for screening of thalassemia patient，it is worthy of clinical promotion and application.
2016 Vol. 23 (10): 120-122 [Abstract] ( 153 ) HTML (38 KB)  PDF  (0 KB)  ( 17 )
123 Relationship research between cervical lesions and high-risk human papilloma virus load
LIU Ai-min;HUANG Shu-hui;YAO Li-feng;CHEN Yi-ping
Objective To explore the relationship between high-risk human papilloma virus　（HPV）load and cervical lesions.Methods 3386 patients accepted high-risk HPV viral load detection in gynecological outpatient clinic of our hospital from May 2013 to June 2014 were selected as the research group，931 cases were in positive infection，who were detected with colposcopy，cervical biopsy and endocervical scraping，and pathological examinations further.According to viral load，all of them were divided into group A（viral load from 1 to 100 pg/ml），group B（viral load from 101 to 500 pg/ml），and group C　（more than 500 pg/ml）.The situation of cervical lesions was observed among each group.Results A total of 446 cases of cervical lesions were diagnosed.Age and viral load in CINⅠ-Ⅲgroup and cervical cancer group was larger than that in the cervicitis group，with significant difference（P＜0.01）.The composition ratio of cervicitis was gradually decreased with the increase of HPV-DNA virus load，with significant difference　（P＜0.01）.The composition ratio of CINⅠ-Ⅲ was gradually increased with the increase of HPV-DNA virus load，with significant difference　（P＜0.01）. There was no significant difference in the composition ratio of cervical cancer with different HPV virus load group　（P＞0.05）.Conclusion The viral load is closely related with cervical lesions.The older patient′s age becomes，the higher the incidences of cervical tumor-like lesion and cancerization are.
2016 Vol. 23 (10): 123-125 [Abstract] ( 138 ) HTML (38 KB)  PDF  (0 KB)  ( 14 )
126 Clinical study of relationship between HBV-DNA viral load in advancedstage pregnancy and mother-to-child transmission of hepatitis B
ZENG Yin;XIAO Qiong;WANG Jian-zhong;SUN Li-ping;ZOU Hai-yan;DING Ying
Objective To explore the relationship between HBV-DNA viral load in advanced-stage pregnancy and mother-to-child transmission of hepatitis B.Methods 88 pregnant women with hepatitis B virus delivered in our hospital from June 2014 to July 2015 were selected and provided with HBV-DNA detection.According to whether the HBVDNA viral load reached 1.0×106IU/ml or not，all of pregnant women were divided into the high viral load group　（n=55）and the low viral load group　（n=33）.The mother-to-child transmission rate of hepatitis B，five detection outcomes of hepatitis B and DNA viral load after delivery in neonates for two weeks，one month，and 7 months in the two groups was compared.Results The mother-to-child transmission rate of hepatitis B in neonates in the high viral load group was 23.08%，which was higher than 6.06%in the low viral load group，with significant difference　（P＜0.05）.The positive detection rate of five items of hepatitis B and HBV-DNA viral load after delivery for two weeks，one month，and 7 months in the high viral load group was higher than that in the low viral load group，with significant difference　（P＜0.05）.Conclusion The higher HBV-DNA viral load in pregnant and lying-in woman is，the more possible the neonate contracts hepatitis B virus infection.
2016 Vol. 23 (10): 126-128 [Abstract] ( 138 ) HTML (34 KB)  PDF  (0 KB)  ( 28 )
129 Effect observation of nasal continuous positive airway pressure combined with gamma globulin in the treatment of severe capillary bronchitis in children
LI Xiu-yun;HUANG Cong-fu;LUO Jian-jun;TANG Yan-li;WU Ying-rao;ZHU Chun-chan
Objective To explore the effect of nasal continuous positive airway pressure（nCPAP）combined with gamma globulin in the treatment of severe capillary bronchitis in children.Methods 70 children with severe capillary bronchitis in our hospital from October 2013 to October 2015 were selected and divided into the observation group and the control group.The observation group was given nCPAP combined with gamma globulin，the control group was given routine oxygen inhalation and symptomatic treatment.The effect of the two groups was compared.Results The hospital stay，the remission time of asthma and the overall time of oxygen inhaling in the observation group was shorter than that in the control group，with significant difference　（P＜0.05）.The respiratory rate and heart rate of the observation group after treatment of 2 hours was lower than that of the control group，the level of TcSO2in the observation group after treatment of 2 hours was higher than that in the control group，with significant difference　（P＜0.05）.The improvement degree of blood gas indexe in the observation group after treatment of 24 hours was better than that in the control group，with significant difference（P＜0.05）.The incidence rate of complication in the observation group was lower than that in the control group，with significant difference　（P＜0.05）.Conclusion nCPAP combined with gamma globulin can improve the ventilation and gas exchange function in children with severe capillary bronchitis，reduce immune injury，relieve the symptoms rapidly，and shorten hospital stay.
2016 Vol. 23 (10): 129-131 [Abstract] ( 125 ) HTML (40 KB)  PDF  (0 KB)  ( 35 )
132 X-ray and CT imaging feature of primary hyperparathyroidism bone disease
JI Xiang;LUO Jun;XU Cui-fang;ZHANG Bai-lin;ZHANG Xiong;LV Jian-guang
Objective To explore the imaging feature of X-ray and CT in primary hyperparathyroidism bone disease. Methods 10 patients with primary hyperparathyroidism bone disease in our hospital from January 2001 to January 2014 were selected as the research group，the imaging feature of X-ray and CT was analyzed.Results Among 10 patients with primary hyperparathyroidism bone diseases，the imaging of X-ray and CT were all manifested with multiple bone involvement，8 cases were osteoporosis，5 cases were presented with subperiosteal bone resorption.All patients were accompanied with osteitis fibrosa cystica or brown tumor.Among 10 cases of primary hyperparathyroidism bone disease，9 cases were adenoma of parathyroid，and 1 case was parathyroid hyperplasia.After CT enhancement scanning in 6 cases，brown tumors were intensified evenly or unevenly.Conclusion Primary hyperparathyroidism bone disease exist universal osteoporosis，when there is the manifestation of subperiosteal bone resorption，osteitis fibrosa cystica or brown tumor，which can be definitely diagnosed combining with parathyroid hormone from laboratory and neck CT examination.
2016 Vol. 23 (10): 132-134转137 [Abstract] ( 142 ) HTML (47 KB)  PDF  (0 KB)  ( 37 )
135 Application value of ultrasonic elastography technique in the diagnosis of breast benign and malignant lesions
YU Bo
Objective To explore the value of ultrasonic elastography technique in the diagnosis of breast benign and malignant lesions.Methods 100 breast lesions patients in our hospital from May 2013 to June 2014 were selected as study object，all patients were diagnosed by ultrasound elastography technique and compared with operation pathology. The sensitivity，specificity and accuracy of the ultrasound elastography technique were analyzed，and the score of benign and malignant ultrasound elastography was compared.Results The sensitivity，specificity and accuracy of the ultrasound elastography technique was 95.38%，88.57%and 93.00%respectively，compared with operation pathology diagnosis，there was no significant difference　（P＞0.05）.The ultrasonic elastography score of breast benign lesions was lower than that of breast malignant lesion，with significant difference　（P＜0.05）.Conclusion Ultrasonic elastography technique has higher diagnosis value for breast benign and malignant lesions，it is worthy of clinical promotion and application.
2016 Vol. 23 (10): 135-137 [Abstract] ( 124 ) HTML (37 KB)  PDF  (0 KB)  ( 33 )
138 Observation effect of dezocine combined with midazolam for sedation infusion in ICU during mechanical ventilation
WANG Guo-wen
Objective To explore the effects of midazolam combined dezocine continuous infusion for sedation in ICU mechanical ventilation.Methods 44 patients who were admitted to ICU and selected mechanical ventilation in our hospital from May 2014 to July 2015 were taken as the research objects and randomly divided into the control group and the study group，22 cases in each group.The patients of two groups were treated with the midazolam while in the study group，on the basis of the treatment，they were treated with the dezocine.Two groups of patients before treatment and 6，12 h and 24 h HR（heart rate），OI（oxygen index），MAP（mean arterial pressure），ramsay score，sedation to achieve the desired effect of the time and the time after withdrawal of the patient′s recovery were observed，compared and adversed reactions occurred during sedation were recorded.Results The sedation of two groups can achieve satisfactory results，in the period of sedation in 44 patients with HR，OI and MAP the relative ratio were significantly improved than before treatment.In the study group，the time of sedation and the recovery time were significantly shorter，and the respiratory depression was lower than that of control group　（P＜0.05）；the adverse reaction in the control group was higher than that of study group（P＜0.05）.Conclusion The midazolam sedation with dezocine intravenous infusion for ICU patients requiring mechanical ventilation，which not only the effect is good，but also is more favorable to maintain the stability of hemodynamics，which can enhance the safety of ICU mechanical ventilation，and the effect of sedation is better.
2016 Vol. 23 (10): 138-140 [Abstract] ( 137 ) HTML (39 KB)  PDF  (0 KB)  ( 32 )
141 Comparing the prevention role of rivaroxaban and low molecular weight heparin in elderly diabetes patients with deep vein thrombosis after total hip replacement
HAO Yin-li;GAO Dong-yan;ZHANG Zhi-qiang;SHI Jin-xiu
Objective To observe the prevention role of rivaroxaban and low molecular weight heparin in elderly diabetes patients with deep vein thrombosis after total hip replacement.Methods 72 patients who conducted total hip replacement underwent elective were selected from May 2014 to August 2015 of our hospital and diagnosed as diabetic from medical department.Patients were randomly divided into group A（rivaroxaban group，n=36）and group B（low molecular weight heparin group，n=36）according to random number table.Patients in group A were given oral administration rivaroxaban 10 h after operation and 10 mg once a day.Patients in group B were given hypodermic injection low molecular weight heparin 10 h after operation with the dose of 4100 IU.Both lower extremities deep veins color doppler ultrasound were conducted both before and after operation to record the incidence rate of deep venous thrombosis and postoperative bleeding.The coagulation markers that before operation and 2 days，7 days and 14 days after operation and fasting blood-glucose value were tested.Results The deep venous thrombosis rate in group A　（2.8%）was lower than that of group B（4.6%），and the difference had no statistical significance（P＞0.05）；the value of D-dimer increased obvious at 2 days and 7 days after operation in both two groups，and the difference was statistical significance（P＜0.05）；the value of D-dimer increased at 7 days and 14 days descended than at 2 days，and the difference was statistical significance（P＜0.05）；compared the D-dimer at 14 days between two group，the difference was statistical significance　（P＜0.05）and the decline scope of D-dimer in group A was more than that of group B；the postoperative bleeding in both two groups had no statistical significance（P＞0.05）；the fasting blood-glucose at all times in two groups had no statistical significance （P＞0.05）.Conclusion Both rivaroxaban and low molecular weight heparin have role in preventing elderly diabetes patients with deep vein thrombosis after total hip replacement.The role of rivaroxaban is better than low molecular weight heparin，there is no obvious increase bleeding and has little effect on blood-glucose.
2016 Vol. 23 (10): 141-143转146 [Abstract] ( 147 ) HTML (42 KB)  PDF  (0 KB)  ( 35 )
144 The clinical study of topiramate combined with sodium valproate in treatment of infantile epilepsy and its effect on metabolism
SONG Yao-hua
Objective To explore clinical efficacy of topiramate combined with sodium valproate in infantile epilepsy. Methods 99 children with epilepsy treated in our hospital from May 2014 to May 2015 were selected and were randomly divided into control group　（n=44）and observation group　（n=45），the control group were treated with sodium valproate，the observation group treated with topiramate combined with sodium valproate.The epilepsy treatment effect，the change of metabolic index and the incidence of adverse reaction were compared between two groups.Results The total effective rate of the observation group was 86.7%，significantly higher than 68.2%of the control group（P＜0.05）.The BMI，leptin/Adiponectin ratio and insulin resistance index had no significant difference between two groups before treatment （P＞0.05）.After treatment，BMI and insulin resistance index in observation group was significantly lower in that of the observation group，Leptin/Adiponectin ratio higher than that of control group（P＜0.05）.There was no significant difference in the incidence of adverse reactions between the two groups（P＞0.05）.Conclusion Topiramate combined with sodium valproate in epileptic children have good clinical effect，can effectively improve the metabolism related indicators，no obvious adverse reactions，it is worth clinical promotion.
2016 Vol. 23 (10): 144-146 [Abstract] ( 145 ) HTML (36 KB)  PDF  (0 KB)  ( 36 )
147 Analysis of application effects of midazolam and propofol in the critical patients receiving mechanical ventilation in emergency
CHEN Jian
Objective To explore the application effects of midazolam and propofol in the critical patients receiving mechanical ventilation in emergency.Methods 79 critical patients receiving mechanical ventilation in emergency who were admitted to the emergency department in our hospital from May 2014 to May 2015 were selected.They were assigned to the control group　（n=39）and the observation group　（n=40）according to the hospitalization order.The control group was given midazolam for sedation，and the observation group was given propofol for sedation.General vital sign changes，drug action time and adverse reactions were compared between the two groups of patients.Results 30 min after drug withdrawal，HR，BP，and PaCO2in the observation group were lower than those of control group，and PaO2was higher than that of control group　（P＜0.05）.The best time of sedative effect，drug action time，and awakening time after drug administration in the observation group were significantly shorter than those of control group　（P＜0.05）.The incidence rate of adverse reactions was 2.5%in the observation group，significantly lower than that of 15.4%in the control group （P＜0.05）.Conclusion Propofol has favorable sedative effects in critical patients receiving mechanical ventilation in emergency，with the characteristics of fast action，and short awakening time after drug withdrawal.However，it has larger inhibiting effects on respiration and blood circulation，but it is highly safe.Sedative drugs should be selected in combination with the specific conditions of the patients clinically.
2016 Vol. 23 (10): 147-149 [Abstract] ( 155 ) HTML (38 KB)  PDF  (0 KB)  ( 42 )
150 Clinical research on low molecular weight heparin combined with zishen yutai pills in treatment of recurrent abortion with positive anticardiolipin antibody
LIANG Rong-li;HUANG Xin;YU Feng-hua
Objective To discuss the clinical effect of low molecular weight heparin（LMWH）combined with Zishen Yutai pills in treatment of recurrent abortion with positive anticardiolipin antibody.Methods 172 patients with recurrent abortion with positive anticardiolipin antibody treated in our hospital from August 2012 to June 2015 were selected and randomly divided into observation group and control group，each group with 86 cases.Patients in the control group were treated by aspirin combined with prednisone，while patients in the observation group were treated by LMWH combined with Zishen Yutai pill.Indexes such as medication duration，live birth rate，antibody clearance rate，etc.of both groups were observed.Results The medication duration was significantly shorter in the observation group　（179.5±12.8）d than that of control group（288.6±14.5）d，with significant difference（P＜0.05）.The live birth rate and antibody clearance rate were significantly higher in the observation group　（91.9%and 79.1%）than that of control group　（65.1%and 37.2%），with significant difference（P＜0.05）.There were only 3 cases（3.5%）of adverse reaction in observation group，which was significantly fewer than that of control group（15cases，17.4%）（P＜0.05）.Conclusion LMWH combined with Zishen Yutai pills in treatment of recurrent abortion with positive anticardiolipin antibody can shorten the medication duration，improve the pregnancy outcome，and increase the antibody clearance rate.
2016 Vol. 23 (10): 150-152 [Abstract] ( 149 ) HTML (36 KB)  PDF  (0 KB)  ( 34 )
153 Local application of local application of pingyangmycin in treating eyelid xanthelasma
WU Fang;LIU Wan-hong
Objective To explore the effects and application value of local application of pingyangmycin in treating eyelid xanthelasma.Methods 119 eyelid xanthelasma patients with larger tumor and younger age were randomly divided into two groups.Patients in study group　（82 cases）were given local application of drug and patients in control group （37 cases）were used laser therapy.The clinical effects，prognosis and recurrence situation in two groups were observed. Results The clinical effects in two groups was equal（P＞0.05）.The rate of local skin itch，congestion swelling and left spots in control group were higher than that of study group　（P＜0.05）.The recurrence rate in study group was lower than that of control group，the patients satisfaction was higher than that of control group，and the difference was statistical significance（P＜0.05）.Conclusion Local injection of pingyangmycin can inhibite the xanthoma cells reproduction，promote the release of lipoprotein lipase and with the advantages of easy，little adverse effects and no recurrence at all.It is worth to popularize and application in clinical practice.
2016 Vol. 23 (10): 153-155 [Abstract] ( 150 ) HTML (38 KB)  PDF  (0 KB)  ( 32 )
156 Analysis of the antimicrobial agents use situation of one hospital from 2014 to 2015
SHEN Shao-qing;GUO Xiao-hui;REN Hao-yang;ZHOU Li-jun;HUANG You-jun
Objective To explore the antimicrobial agents use situation of one hospital from 2014 to 2015 and to provide reference basis for clinical application and management of antimicrobial agents.Methods Drug consumption sum ratio，constituent ratio of all kinds of antimicrobial agents drug consumption sum，antimicrobial agents detail that on the top 10 of DDDs，usage rate of antimicrobial agents，antimicrobial agents use intensity of inpatient，antimicrobial agents prevention usage rate for typeⅠincision and microbial sample inspection rate before using antimicrobial agents from 2014 to 2015 of this hospital were selected and counted.Variation trend of all index between two years was compared by making chart.Results The drug consumption sum ratio of antimicrobial agents in this hospital was maintained about 17%.The drug consumption sum ratio of β-lactamase inhibitors and compound preparations of beta lactam antibiotics compatibility was highest　（about 35%）.The top 3 DDDs of all kinds of antimicrobial agents were following as quinolones，cephalosporins and macrolides.The top 3 of single use frequency were following as levofloxacin tablet，amoxacllin capsule and clarithromycin tablet.Compared with 2014，the antimicrobial agents usage rate of outpatient，emergence and inpatient respectively decreased 0.23%，-14.77%and 3.26%.Antimicrobial agents use intensity of inpatient patients decreased 4.15 DDDs/hundreds of people every day.Antimicrobial agents prevention usage rate for typeⅠincision decreased 9.21%.Microbial sample inspection rate of overall，limit use and special level use of antimicrobial agents were respectively increased 21.57%，19.42%and 31.63%.Conclusion The hospital antimicrobial drug use gradually tend to be more reasonable，but some indicators have not yet reach the national requirements and still need to further improve management and training.
2016 Vol. 23 (10): 156-160 [Abstract] ( 166 ) HTML (54 KB)  PDF  (0 KB)  ( 41 )
161 Application investigation of non-invasive positive pressure ventilation in acute respiratory failure in ICU
ZHANG Zong-mian;LIANG Wei-can;GUAN Zi-yun;YE Wen-hua;LUO Jian-cheng;CAO Feng-ping
Objective To explore the application situation of non-invasive positive pressure ventilation（NPPV）in acute respiratory failure in ICU.Methods 1254 patients with acute respiratory failure treated in ICU in our hospital from January 2011 to December 2014 were selected and randomly divided into two groups.Patients in the two groups was given NPPV first-line therapy and invasive ventilation first-line therapy respectively.The situation of treatment in the two groups was evaluated.Results The SAPSⅡscore of patients given NPPV first-line therapy was lower than that of patients given invasive ventilation first-line therapy，with significant difference（P＜0.01）.The disease patterns of patients given NPPV first-line therapy were mainly AECOPD（47.95%）and ACPE（15.78%），and the proportion of patients was increased yearly from 2011 to 2014，namely 12.09%，27.87%，28.89%，and 31.15%respectively.The success rate of NPPV first-line therapy was 40.16%.The age of the NPPV treatment success group was less than that of the failure group，the time in ICU and hospital stay time in the NPPV treatment success group was shorter than that in the failure group，with significant difference　（P＜0.05）.The SAPSⅡ score in the NPPV treatment success group was higher than that in the failure group，with significant difference　（P＜0.01）.The proportion of patients of AECOPD，ACPE and postoperative respiratory failure in the NPPV treatment success group was higher than that in the failure group，the proportion of pneumonia and ALI/ARDS patients in the NPPV treatment success group was lower than that in the failure group，with significant difference　（P＜0.05）.Conclusion In ICU of grade-3 and the first-class general hospitals，the total proportion of NPPV in the treatment of acute respiratory failure is low，but increased year by year.AECOPD and ACPE are common patterns of disease and are relative to the success rate of NPPV treatment.NPPV can shorten the time in ICU and hospital stay of patients.
2016 Vol. 23 (10): 161-164 [Abstract] ( 128 ) HTML (42 KB)  PDF  (0 KB)  ( 30 )
165 Report analysis of the five results of hepatitis B in pregnant women of pregnancy prenatal examination
TANG Hai-yan
Objective To explore the prevalence situation of hepatitis B in pregnant women and the content of hepatitis B surface antibody in each age group，and to provide reference data for the reasonable inoculation of hepatitis B vaccine.Methods 2276 pregnant women in our hospital from January 2013 to July 2015 were selected as the research group，five quantification of hepatitis B was detected by time resolved fluorescence immunoassay　（TRFIR）.Results In 2276 cases of pregnant women，312 cases of hepatitis B were positive，the infection rate was 13.7%.45.5%patients showed that the HBsAg，HBeAb，HBcAb were positive，39.4%patients showed that the HBsAg，HBeAg，HBcAb were positive，8.9%patients showed that the HBcAb，HBsAg were positive，1.9%patients showed that the HBeAg，HBsAg were positive，0.9%patients showed that the HBsAg was positive，1.9%patients showed that the HBeAb，HBsAg was positive，1.3%patients showed that the HBsAb，HBsAg was positive.The content of HBsAg in the 20-25 years old group was lower than that in 26-30 years old group and 31-40 years old group，with significant difference　（P＜0.05）.There was no significant difference in the content of HBsAg between 26-30 years old group and 31-40 years old group　（P＞0.05）.In 2276 pregnant women，1182 cases of hepatitis B surface antibody were positive，and the positive rate was 51.9%.The positive rate of HBsAb and high immune response rate in 26-30 years old group was higher than that in 20-25 years old group and 31-40 years old group，with significant difference　（P＜0.05）.The low immune response rate in the 20-25 years old group was higher than that in 26-30 years old group and 31-40 years old group，with significant difference （P＜0.05）.Conclusion For pregnant women infected with HBV and susceptible to HBV infection，the quantitative detection of hepatitis B can reflect to the dynamic immune situation of hepatitis B infection，which is conducive to the control of HBV infection and prevention of mother to child transmission for eugenics.
2016 Vol. 23 (10): 165-167转170 [Abstract] ( 127 ) HTML (38 KB)  PDF  (0 KB)  ( 32 )
168 Analysis of infectious distribution and tolerance of Acinetobacter baumannii in a hospital
WANG Wei-wei
Objective To explore the infectious distribution，specimen source and tolerance of Acinetotacter baumannii and to provide theoretical evidences for the prevention of the occurrence of infection and multi-drug resistant bacteria. Methods 4383 bacteria were separated from the patients who were admitted in our hospital from July 2014 to June 2015.In this research，the detective rate，specimen sources and tolerance of 370 Acinetotacter baumannii were analyzed，and the data were processed by SPSS 17.0.Results From July 2014 to June 2015，the separation rate of Acinetotacter baumannii in ICU was 49.49%and the separation rate of non-ICU Acinetotacter baumannii was 5.50%，there was significant difference　（P＜0.01）.In 370 Acinetotacter baumannii，more than 80%came from sputum specimen.The tolerance rate of Acinetotacter baumannii in ICU wards was higher than that in non-ICU wards besides polymyxin E and tigecycline，with significant difference（P＜0.01）.Conclusion Acinetotacter baumannii in this hospital mainly distribute in ICU wards with relative high tolerance.Great attention should be paid and preventive measures should be taken to prevent the occurrence of infection and multi-drug resistant bacteria.
2016 Vol. 23 (10): 168-170 [Abstract] ( 130 ) HTML (35 KB)  PDF  (0 KB)  ( 28 )
171 Incidence and prevention and control status surveying of hand，foot and mouth disease in Bijie childcare facilities
CHEN Mei;SONG Shen-chao;FAN Cai-ping
Objective To understand the awareness degree of prevention and treatment knowledge of related personnel in Bijie childcare facilities and to explore the incidence status in recent years and to provide scientific basis for making prevention and control strategy.Methods The related situation of hand，foot and mouth disease in Bijie childcare facilities from 2008 to 2012 were investigated.Data over the years that acquired from the Chinese center for disease control and prevention information system were obtained.Results The incidence rate of hand，foot and mouth disease in Bijie childcare facilities had a tendency to rise year by year，the incidence rate in boys was higher than that in girls，with significant difference　（P＜0.05）.There was still inadequate aspects for the prevention and control of hand foot and mouth disease in the childcare facilities.The mean pass rate of Disinfecting apparatus equipment，disinfection measures，executive condition and health education were not high.Conclusion The incidence rate of hand，foot and mouth disease in Bijie childcare facilities had a tendency to rise year by yea，the incidence rate of boys are higher than that girls，the awareness degree of prevention and treatment knowledge of nursery and infant institutions is lack and publicity and commitment the supervise the preventive measures of hand foot and mouth disease knowledge should be strengthen.
2016 Vol. 23 (10): 171-173 [Abstract] ( 116 ) HTML (39 KB)  PDF  (0 KB)  ( 34 )
174 The role of total nursing model in improving the living ability of rehabilitation schizophrenia patients
FENG Xing
Objective To explore the role and effects of application total nursing model in rehabilitation schizophrenia patients.Methods 130 patients with rehabilitation schizophrenia of our hospital were selected as study objects and were divided，65 cases in each group.Patients in control group were given routine nursing and patients in study group were given total nursing on the basis of routine nursing.Results The grasp rate of disease-related knowledge and health education satisfaction in study group were obvious higher than that of control group；The early recovery rate and on time discharge rate in study group were obvious higher than that of control group；The recurrence rate of disease in study was obvious lower than control group　（P＜0.05）.The MRSS and SDSS score in both two groups were obvious lower than before nursing and the study group was obvious lower than that of control group（P＜0.05）.Conclusion Application total nursing model in rehabilitation schizophrenia patients can obvious enhance nursing effects，is helpful to improve living ability and has positive meaning for stabilized condition.
2016 Vol. 23 (10): 174-176 [Abstract] ( 125 ) HTML (35 KB)  PDF  (0 KB)  ( 4 )
177 Application effect of collaborative care model in the elderly patients with diabetic nephropathy in peritoneal dialysis
QIN Fei
Objective To evaluate the effect of collaborative care model on elderly patients with diabetic nephropathy in peritoneal dialysis.Methods 138 cases of elderly diabetic nephropathy treated in our hospital were randomly divided into the observation group and the control group，69 cases in each group.The control group took the traditional nursing mode for nursing，the observation group adopted the cooperative nursing mode to carry on the systematic nursing.The quality of life score，Zung depression score and the incidence of complications were compared between two groups.Results After nursing intervention，the quality of life score，Zung depression score　（0.56±0.02）and the total complication rate（8.70%）were significantly better than Zung depression score（0.61±0.07）and the total complication rate（36.23%）of the control group，and the difference was statistically significant（P＜0.05）.Conclusion Application of collaborative nursing model on elderly diabetic nephropathy patients by peritoneal dialysis can effectively relieve patients with tension，anxiety，patients with higher quality of life，has a more comprehensive understanding of peritoneal dialysis process，attention and related knowledge，but the long-term clinical effect is still need to be confirmed by prolonging follow-up time and increasing the sample size.
2016 Vol. 23 (10): 177-179 [Abstract] ( 123 ) HTML (38 KB)  PDF  (0 KB)  ( 22 )
180 Intervention role of community postpartum visit nursing service in neonatal jaundice
LI Gui-xian
Objective Case history data of children with neonatal jaundice were retrospectively analyzed and to explore the role of community postpartum visit nursing service and early screening neonatal pathologic jaundice in decreasing sequel result from that.Methods Case history data of 100 children with neonatal jaundice from September 2012 to September 2015 of our hospital were retrospectively analyzed.50 newborns who got postpartum visit at 7 days and 14 day after birth were divided as observation group and 50 newborns who did not get community postpartum visit nursing service were divided as control group.The treatment effects of two children patients with jaundice were compared.Results The treatment effects in observation group was obvious higher than that of control group，and the difference was statistical significance when compared between two groups（P＜0.05）.Conclusion Through community postpartum visit nursing service can find children with pathological jaundice as soon as possible，make them to get treatment timely，decrease the damage and sequel that kernicterus brings to children patients and decrease family financial burden and family members psychological burden results from children patients kernicterus.
2016 Vol. 23 (10): 180-182 [Abstract] ( 120 ) HTML (36 KB)  PDF  (0 KB)  ( 33 )
183 Application of continuing nursing by WeChat in discharged patients with non-severe aplastic anemia
DAI Xiao-ying;CHEN Ning-ping
Objective To explore the application effect of continuing nursing by WeChat in discharged patients with non-severe aplastic anemia（NSAA）.Methods From May to December 2014，44 NSAA patients were evenly divided into continuing nursing group and conventional nursing group in random.In the conventional nursing group，only regular guidance on discharge and telephone follow-up were provided，while in the continuing nursing group on the basis of the conventional nursing group by WeChat was continued even after being discharged from hospital.Results Six months after being discharged from hospital，efficacy in the continuing nursing group was in increasing trend compared with that in the conventional nursing group，and self-care ability and satisfaction were both improved with statistical differences （P＜0.05）.Conclusion For NSAA patients discharged from hospital，application of continuing nursing by We Chat can improve patients self-care ability and satisfaction，but is uncertain for enhancing efficacy.
2016 Vol. 23 (10): 183-185 [Abstract] ( 148 ) HTML (42 KB)  PDF  (0 KB)  ( 42 )
186 Application effects of intensive nursing intervention in GVHD after allogeneic hematopoietic stem cell transplantation
ZENG Wei
Objective To explore the promotion role of intensive nursing intervention in GVHD after allogeneic hematopoietic stem cell transplantation.Methods 57 GVHD after allogeneic hematopoietic stem cell transplantation patients from March 2013 to December 2015 of our hospital were selected as study object.Patients were random divided into intensive group（n=33）and routine group（n=24）.The course duration，hospital stay，anxiety，depression score and nursing satisfaction of patients in two groups were compared.Results The course duration，hospital stay，anxiety and depression score in intensive group were lower than that of routine group（13.5±2.4）d vs（16.9±2.8）d，（16.7±3.1）d vs（21.5± 2.8）d，（9.7±2.0）points vs（13.5±2.4）points，（35.4±8.7）points vs（46.7±9.1）points（P＜0.05）.The nursing satisfaction of patients in intensive group（96.97%）was higher than routine group（79.19%）（P＜0.05）.Conclusion Using intensive nursing intervention in GVHD after allogeneic hematopoietic stem cell transplantation can relief adverse emotion of patients，decrease treatment time，hospital stay and enhance satisfaction of patients.
2016 Vol. 23 (10): 186-188转191 [Abstract] ( 158 ) HTML (38 KB)  PDF  (0 KB)  ( 39 )
189 Application effect observation of pure breast-feeding in premature infant
WEN Ai-yan;HUANG Dong-ying;HUANG Chun-ju
Objective To explore the application effect of pure breast-feeding in premature infant.Methods 90 premature infants from January 2015 to September of our department were selected and divided into the observation group and the control group according to breast-feeding situation，45 cases in each group.The observation group was given pure breast-feeding group，the control group was given formula feeding.The hospital stay，hospital fees and the incidence of complication in the two groups was compared.Results The hospital stay in the observation group was shorter than that in the control group，the hospital fees in the observation group was less than that in the control group，with significant difference　（P＜0.05）.There was no significant difference in the incidence of complication between two groups（P＞0.05）.Conclusion Pure breast-feeding can decrease the hospital stay，hospital fees of premature infant.
2016 Vol. 23 (10): 189-191 [Abstract] ( 138 ) HTML (35 KB)  PDF  (0 KB)  ( 38 )
192 Applications effects of high quality nursing service is used in under the thoracoscope linear cutting anastomat surgery which treatment for pulmonary bulla patients
HUANG Li-qun
Objective To explore the effects of high quality nursing service is used in under the thoracoscope linear cutting anastomat surgery which treatment for pulmonary bulla patients.Methods Clinical data of 108 pulmonary bulla patients from September 2012 to September 2015 of our hospital were selected，Patients were divided into control group （n=54）and high quality nursing service group　（n=54）according to nursing measures.The incidence rate of complications，hospital stay and satisfaction of pulmonary bulla patients in two groups were observed.Results The pulmonary infection，prolonged air leaks and incidence rate of active bleeding of pulmonary bulla patients in high quality nursing service group were respectively 0，0 and 0，which were lower than were respectively 7.4%，7.4%and 7.4%.The hospital stay of pulmonary bulla patients in high quality nursing service group was（6.8±3.0）d，lower than that was（11.5±2.6）d in control group；The satisfaction was 100%，higher than that was 88.9%in control group，and the difference was statistical significance　（P＜0.05）.Conclusion High quality nursing service is used in under the thoracoscope linear cutting anastomat surgery which treatment for pulmonary bulla patients can obvious decrease the incidence rate of complications，enhance patients satisfaction and is worth to popularize and application in clinical.
2016 Vol. 23 (10): 192-194 [Abstract] ( 134 ) HTML (36 KB)  PDF  (0 KB)  ( 11 )
195 Risk of maternal implentation method and effects of high quality nursing service
XU Feng
Objective To explore the high quality nursing method and effects of risk pregnant women.Methods 90 risk pregnant women from June 2013 to June 2015 of our hospital were selected and divided into control group（routine nursing）and experimental group　（quality nursing）according to different nursing methods.There were 45 cases in each group.The delivery outcomes were observed and the satisfactory degree of nursing was evaluated.Results 42　（93.3%）cases had satisfactory nursing in experimental group and 4（8.9%）cases occurred maternal and neonatal complications. 35（77.8%）cases had satisfactory nursing in experimental group and 12（26.7%）cases occurred maternal and neonatal complications.After nursing，the anxious score and depression score of pregnant women decreased obviously and the decreased degree in experimental group was better than that of control group，and the difference was statistical significance（P＜0.05）.Conclusion Risk pregnant women have high risk in delivery and carrying out quality nursing has positive meaning.It can enhance nursing service quality，improve psychological state，get satisfactory delivery outcomes and is worth to popularize in clinic.
2016 Vol. 23 (10): 195-197 [Abstract] ( 129 ) HTML (43 KB)  PDF  (0 KB)  ( 30 )
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