高危型人乳头瘤病毒负荷量与宫颈病变的关系研究

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Abstract Objective To explore the relationship between high-risk human papilloma virus　（HPV）load and cervical lesions.Methods 3386 patients accepted high-risk HPV viral load detection in gynecological outpatient clinic of our hospital from May 2013 to June 2014 were selected as the research group，931 cases were in positive infection，who were detected with colposcopy，cervical biopsy and endocervical scraping，and pathological examinations further.According to viral load，all of them were divided into group A（viral load from 1 to 100 pg/ml），group B（viral load from 101 to 500 pg/ml），and group C　（more than 500 pg/ml）.The situation of cervical lesions was observed among each group.Results A total of 446 cases of cervical lesions were diagnosed.Age and viral load in CINⅠ-Ⅲgroup and cervical cancer group was larger than that in the cervicitis group，with significant difference（P＜0.01）.The composition ratio of cervicitis was gradually decreased with the increase of HPV-DNA virus load，with significant difference　（P＜0.01）.The composition ratio of CINⅠ-Ⅲ was gradually increased with the increase of HPV-DNA virus load，with significant difference　（P＜0.01）. There was no significant difference in the composition ratio of cervical cancer with different HPV virus load group　（P＞0.05）.Conclusion The viral load is closely related with cervical lesions.The older patient′s age becomes，the higher the incidences of cervical tumor-like lesion and cancerization are.

Key words： High-risk human papilloma virus Load Age Cervical lesions

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	Articles by authors
	LIU Ai-min
	HUANG Shu-hui
	YAO Li-feng
	CHEN Yi-ping

Cite this article:

LIU Ai-min,HUANG Shu-hui,YAO Li-feng, et al. Relationship research between cervical lesions and high-risk human papilloma virus load[J]. 中国当代医药, 2016, 23(10): 123-125.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I10/123

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