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Quick Search     Adv Search 2017 Vol. 24, No. 25 Published: 2017-09-08   4 Influence of Cyclosporine A on the differentiation of mouse embryonic stem cells into cardiomyocytes and its regulatory mechanism YAN Pei-shi, DUAN Li-qin, BI Sha-sha, WANG Xiao-xu Objective To explore the influence of Cyclosporine-A (CSA) on the differentiation of mouse embryonic stem cells (ESCs) into cardiomyocytes and its mechanism of regulation.Methods The differentiation system of mouse embryonic stem cells into cardiomyocytes by stages was used,and ESCs spontaneous group and CSA induction group were designed.The differentiation rate and count of cardiomyocytes were evaluated by cell immunohistochemistry and flow cytometry (FACS).The expression of CSA-induced cardiomyocyte markers was detected by cell immunohistochemistry.CSA was added at different stages of ES cell differentiation to observe whether CSA specifically acted on a particular differentiation phase.Another immunosuppressive agent including tacrolimus (calcineurin inhibitor:FK506) or 11R-VIVIT (nuclear factor of activated T cells:NFAT) was separately added in order to compare the differentiation rate of cardiomyocytes among the groups.Results In the ESCs spontaneous group,the differentiation rate of cardiomyocytes was (6.00±0.05)%,and the rate in the CSA-induction group was (60.00±0.08)%,which was displayed a statistical difference (P<0.05).The cardiomyocytes generated from induction possessed the unique characteristics.CSA specifically acted on mesodermal stem cells and promoted the differentiation of these cells into cardiac stem cells.The amount of myocardial cells was increased differentiated from mesodermal stem cells strongly promoted by CSA,while the number into epithelial cells was in decrease.After adding FK506 and 11R-VIVIT,there was no similar effect of CSA on promotion of cardiomyocyte differentiation.Conclusion Cyclosporine-A specifically acts on mesodermal stem cells and can powerfully induce these ESCs into the differentiated cardiomyocytes via non-NFAT pathway. 2017 Vol. 24 (25): 4-4 [Abstract] ( 502 ) HTML (1 KB)  PDF (916 KB)  ( 154 ) 8 Meta-analysis of the therapeutic effect and safety of silymarin in the treatment of nonalcoholic fatty liver disease HUANG Qian, WU Yin-lian, KANG Na-ling Objective To evaluate the therapeutic effect and safety of silymarin in the treatment of nonalcoholic fatty liver disease (NAFLD).Methods RCT articles about treating NAFLD with silymarin were published in databases including PubMed,Embase,the Cochrane Library,CBM,Wanfang Data,VIP,and CNKI before July 2016 were searched.The included articles were used to extract data and assess the methodology quality according the inclusion/exclusion criteria.Then all the datas were analyzed with RevMan 5.3.Results A total of 14 artilces including 1337 cases were fitted for Meta-analysis.After treatment,ALT,AST,TG and BMI were significant different between silymarin-treated group and control group (ALT:WMD=-14.16,95%CI (-22.02,-6.30),P=0.0004;AST:WMD=-9.17,95%CI (-14.20,-4.15),P=0.0003;TG:WMD=-0.23,95%CI (-0.42,-0.03),P=0.02;BMI:WMD=-0.84,95%CI (-1.34,-0.34),P=0.001.The subgroup analysis showed ALT and AST were significantly different between silymarin-treated group and control group in NAFLD cases,but not in NASH cases.The adverse reactions were low and mild.Conclusion Silymarin can improve ALT,AST,TG and BMI with low adverse reactions according limited evidence for now. 2017 Vol. 24 (25): 8-13 [Abstract] ( 320 ) HTML (1 KB)  PDF (1293 KB)  ( 142 ) 13 Research progress of gastroesophageal reflux disease HAN Meng-ting, LI Zhi-jian, Silafu·AIBAI Gastroesophageal reflux disease is a type of disease that stomach esophagus is exposed to gastric acid,which always firstly manifested as gastroesophagal reflux and esophageal mucosal injury.Currently,its researches have been catching more attention.This review summarize the various literatures on the pathogenesis of GERD,treatment drugs,animal models and other aspects,in order to obtaining new ideas and clues for study of gastric esophageal reflux disease. 2017 Vol. 24 (25): 13-16 [Abstract] ( 397 ) HTML (1 KB)  PDF (373 KB)  ( 316 ) 17 Effect observation of ostomy bag combined with intermittent irrigation and negative pressure suction in fecal incontinence patients LIU Yan, HUANG You-ping, LIANG Xiao-ming, CAI Fang-fang, CHEN Zhi-yan, HUANG Yan-ling ] Objective To investigate the effect of self-made fecal collection kits combined with intermittent irrigation and negative pressure suction in fecal incontinence patients.Methods A total of 80 fecal incontinence patients treated in our hospital from January 2015 to February 2017 were selected as research objects in this study.All of the patients were divided into observation group and control group according to the random number table method,with 40 cases in each group.The feces of the observation group were collected with a self-made fecal collection kits combined with intermittent irrigation and negative pressure suction.The feces of the control group were collected with a self-made ostomy bag combined with negative pressure suction.The leakage times and replacement times of ostomy bag,the number of nursing staff needed to replace ostomy bag and the comfort degree of the patients in the two groups were compared.Results Leakage times and replacement times of ostomy bag in the observation group were significantly lower than those in the control group;the number of nursing staff needed to replace ostomy bag was less in the observation group than in the control group;the patient was more comfortable than the control group,and the differences were statistically significant (P<0.05).Conclusion The self-made fecal collection kits combined with intermittent irrigation and negative pressure suction can effectively can reduce the leakage of the ostomy bag and the frequency of replacement,and reduce the nursing workload.The self-made fecal collection kits have the advantages of simple manufacture,convenient material drawing and convenient operation,and is worthy of clinical application. 2017 Vol. 24 (25): 17-19 [Abstract] ( 235 ) HTML (1 KB)  PDF (628 KB)  ( 111 ) 20 Clinical study of painless endoscopic injection of hemostasis combined with high dose Esomeprazole in the treatment of peptic ulcer bleeding ZHOU Lei, SU Chu-xia, LI Chun-nan, DING Zi-le Objective To investigate the clinical efficacy of painless endoscopic injection of hemostasis combined with high-dose Esomeprazole in the treatment of peptic ulcer bleeding.Methods 90 case of peptic ulcer bleeding patients in our hospital from March 2015 to February 2017 were selected and randomly divided into group A(30 patients with high-dose Esomeprazole),group B(painless endoscopic injection of hemostatic combined with conventional doses of Esomeprazole,30 patients),group C(painless endoscopic injection of hemostasis combined with high-dose Esomeprazole treatment,30 cases),The three groups of stop bleeding time,length of stay,hospital costs and re-bleeding and surgery were compared.Results The time of stop bleeding,hospitalization and hospital costs were higher in group A than those in group B and group C.The time of stop bleeding,hospitalization and hospital costs in group B were higher than those in group C（P<0.01）.The rate of rebleeding was higher in group A than that in group C,and the rate of operation was higher than that of group B and C(P<0.05).Conclusion Painless Endoscopic injection of hemostatic combined with high doses of esomeprazole in patients with peptic ulcer bleeding treatment can improve the hemostatic effect,reduce the incidence of rebleeding. 2017 Vol. 24 (25): 20-22 [Abstract] ( 255 ) HTML (1 KB)  PDF (519 KB)  ( 125 ) 23 Clinical effect comparison of laparoscopic and traditional hernia tension-free repair LIN Jun-shuang Objective To investigate the clinical effect of laparoscopic and traditional hernia tension-free repair.Methods From January 2015 to December 2016,64 patients with inguinal hernia treated in our hospital were selected as subjects,and they were randomly divided into two groups by the computer method,each group with 32 cases.The control group was used traditional hernia tension-free repair and the observation group was used laparoscopic inguinal hernia tension-free repair.Perioperative index,incidence rate of complications and wound healing of two groups were compared.Results The time of operation,postoperative pain and hospital stay in observation group were (16.58±5.76)min,(4.23±2.05)d and (2.88±1.26)d respectively,they were shorter than the control group (30.85±9.37)min,(7.54±2.12)d, (5.69±1.43)d,the differences were statistical significance (P<0.05).The intraoperative blood loss in the observation group was (3.47±0.52)ml it was less than the control group [(7.13±0.55)ml],and the difference was statistically significant (P<0.05).The incidence of complications was lower in the observation group (9.52%) than that in the control group (28.57%),and the difference was statistically significant (P<0.05).Incidence rate of complications was 9.52%,lower than that in the control group (28.57%)(P<0.05).The wound healing in the observation group was better than the control group,and the difference was statistically significant (P<0.05).Conclusion The effect of aparoscopic inguinal hernia tension-free repair in treating inguinal hernia patients is better than traditional hernia tension-free repair,and it is suitable for clinical application. 2017 Vol. 24 (25): 23-25 [Abstract] ( 247 ) HTML (1 KB)  PDF (519 KB)  ( 69 ) 26 Emergency treatment and influencing factors of craniocerebral hernia combined with hemorrhagic shock XU Dong-sheng, ZHANG Ye, WANG Zhong-xiang ] Objective To analyze and judge the emergency treatment and influencing factors of craniocerebral hernia combined with hemorrhagic shock.Methods From February 2015 to January 2016,60 patients with cerebral hernia combined with hemorrhagic shock treated in our hospital were selected as the research objects.The emergency measures of different schemes were given according to the grade of shock and cerebral hernia.The effect of cerebral herniation on therapeutic effect were analyzed and compared.Results Among the 60 patients,7 cases died,the survival rate was 88.33%,the total effective rate of treatment was 70.00%.The total effective treatment rate of patients with cerebral hernia levelⅠ was higher than level Ⅱ and Ⅲ,the differences was statistically significant (P<0.05).The S100B protein concentration and neural function defect scale of patients with cerebral hernia levelⅠafter treatment were lower than the patients with level Ⅱ and Ⅲ,the difference was statistically significant (P<0.05).Conclusion The cerebral hernia level and operation method will affect the clinical curative effect and prognosis of patients after treatment.When the operation procedure is correct and no difference is made,cerebral hernia level is the main influence factor,it needs attention in clinic. 2017 Vol. 24 (25): 26-28 [Abstract] ( 275 ) HTML (1 KB)  PDF (518 KB)  ( 65 ) 29 Exploration of the clinical characteristics and therapeutic effect in senile stroke patients combined with aspiration pneumonia PENG Zi-cheng Objective To explore the clinical characteristics and therapeutic effect on senile stroke patients combined with aspiration pneumonia.Methods From January 2015 to October 2016,120 cases of senile cerebral apoplexy patients treated in our hospital were selected as the research objects,60 cases of senile stroke patients combined with aspiration pneumonia as experimental group,60 cases without aspiration pneumonia senile stroke patients as normal group.The clinical manifestations of aspiration pneumonia,pulmonary imaging examination,outcome of sputum culture,relevant risk factors,disease treatment and prognosis were analyzed.Results In the experimental group,there were 31 cases with typical manifestations of respiratory system,and 29 cases were absent.There were 7 cases presented with lobe or segment consolidation shadow and atelectasis.51 cases were in inferior lung.44 cases were ascribed to pathogen growth.Compared the basic information of patients in the two groups,showed that age,albumin level,smoking history,combination of diabetes mellitus,disturbance of consciousness,antacids,nasogastric time were risk factors of aspiration pneumonia,the differences were statistically significant (P<0.05).Conclusion For senile stroke patients,the clinical manifestations of aspiration pneumonia lack typical characteristics.If in sputum culture,the pathogenic bacteria are complex and diverse.The prevention of these diseases should be paid attention to. 2017 Vol. 24 (25): 29-31 [Abstract] ( 379 ) HTML (1 KB)  PDF (519 KB)  ( 95 ) 32 Influence of rehabilitation exercise on cardiac function in patients with coronary heart disease at a stable stage ZHOU Mi, LI Yun, ZHONG Cai-xiu, YANG Zhi-hua Objective To observe the changes of cardiac function in patients with coronary heart disease (CHD) at a stable stage after rehabilitation exercise.Methods A total of 160 patients with stable CHD treated in Department of Cardiovascular Medicine of our hospital were selected and divided into treatment group (n=90) and control group (n=70).In the control group,the basic medication on CHD was provided,while in the treatment group,besides the basic medication,a unified regimen of rehabilitation exercise was added.The changes of cardiac function indexes before experiment and four-week after therapy were compared.What′s more,participants in the treatment group were further divided into short-term treatment group (4-week therapy,n=50) and long-term treatment group (12-week therapy,n=40).The cardiac functions in the short-term treatment,long-term treatment,and control groups were compared.Results Compared with the control group,the indexes of 6-minute walkingtest,maximal metabolic equivalent (METs),grading of NYHA cardiac function,and left ventricular ejection fraction (LVEF) were greatly improved in the treatment group after 4 weeks of treatment (P<0.05).The indexes of 6-minute walkingtest,METs,grading of NYHA cardiac function,and LVEF in the long-term treatment group were superior to those with only 4-week treatment in the same group,the short-term treatment group after 12 weeks,and the control group after 12 weeks (P<0.05).After 12 weeks,the indexes in the short-term treatment group and control group were not displayed statistical differences (P>0.05).Conclusion Rehabilitation exercise therapy is beneficial to improve the cardiac function in patients with stable CHD,and the effect is more significant in a continuous and regular way. 2017 Vol. 24 (25): 32-35 [Abstract] ( 273 ) HTML (1 KB)  PDF (456 KB)  ( 114 ) 36 Clinical study of stent implantation in the treatment of Stanford type B aortic dissection XI Hai-long Objective To investigate the clinical efficacy of stent graft in Stanford type B aortic dissection （AD）.Methods From January 2012 to December 2014,60 patients with type B AD treated in our hospital were selected and randomly divided into conservative treatment group (30 cases) and intervention group (30 cases).The patients were treated with conservative treatment and interventional treatment of stent graft.The mortality rate,complication rate,hospitalization time and blood pressure target achievement rate,treatment compliance and survival rate were observed at 2 years after discharge.Results The length of hospital stay in the intervention group [(26.1±10.1)d] was significantly lower than that in the conservative treatment group (33.9±17.8) d,the difference was statistically significant（P<0.05）.After 2 years of discharge,the blood pressure target achievement rate (93.33%),survival rate(93.33%) and treatment adherence(93.33%) of intervention group were significantly higher than those in the conservative treatment group(60.00%,53.33%,73.33%),the difference was statistically significant（P<0.05）.Conclusion The patients with type B AD underwent endovascular surgery,which not only rapid recovery,has fewer postoperative complications,but also has higher survival rate,good long-term and short-term curative effect.Should be promoted. 2017 Vol. 24 (25): 36-38 [Abstract] ( 221 ) HTML (1 KB)  PDF (406 KB)  ( 186 ) 39 Randomized controlled study of loading dose of Sodium Valproate and Olanzapine in treatment of bipolar Type Ⅰ disorder patients with manic episode YU Hua, WAN Jian-guo Objective To investigate the efficacy and safety of loading dose of Sodium Valproate combined with Olanzapine in the treatment of bipolar type Ⅰ disorder patients with manic episode.Methods Altogether 80 cases of bipolar type Ⅰ disorder patients with manic episode who were treated in our hospital from January 2015 to October 2016 were randomly divided into treatment group and control group,with 40 cases in each group.Control group was treated with olanzapine;while,treatment group was treated with the loading dose of Sodium Valproate.The therapeutic effects of the two groups were compared.Results The effective rate of treatment group were 82.50% versus control group′s 77.50%,without statistically significant difference between the two groups (P>0.05).The postoperative YMRS (Young Manic Rating Scale) and BPRS (Brief psychiatric Rating Scale) scores of treatment group were (7.4±5.3) and (8.8±3.5) score,compared with control group [(9.8±3.5),(13.5±7.4)scores],with statistically significant difference (P<0.05).The HAMD (Hamilton Rating Scale for Depression) score (4.5±1.7) of treatment group was lower than that of control group (4.7±2.7),without statistically significant difference (P>0.05).The incidence of adverse reactions of treatment group was 7.50% versus control group′s 25.00%,with statistically significant difference between the two groups (P<0.05).Conclusion The efficacy of application of the loading dose of Sodium Valproate is similar to that of Olanzapine in the treatment of bipolar type Ⅰ disorder patients with manic episode,which has less adverse reactions and is worthy of wide clinical use. 2017 Vol. 24 (25): 39-41 [Abstract] ( 381 ) HTML (1 KB)  PDF (552 KB)  ( 160 ) 42 Clinical effect of unilateral coronal suture with frontal approach resection treating brain tumor ZHAN Xin-hua Objective To explore the clinical effect of unilateral coronal suture with frontal approach resection treating brain tumor.Methods 18 patients with brain tumor treated in our hospital from July 2014 to June 2016 were selected.Patients were divided into the observation group and control group according to treatment method,and each group had 9 cases.The observation group was given unilateral coronal suture with frontal approach resection treatment,and the control group was given general resection.The treatment effect between the two groups was compared.Results The excellent rate in observation group was 88.89%,which was higher than that of the control group (44.44%) (P<0.05).The neurologic impairment score in the observation group was lower than that of the control group after treatment (P<0.05).The recurrence rate in the observation group was lower than that of the control group,the recurrence time was longer than that of the control group,and recovery time was shorter than of the control group (P<0.05).The total complications rate in observation group was lower than that of the control group (P<0.05).Conclusion Unilateral coronal suture with frontal approach resection treating brain tumor can effectively improve neurologic impairment,decrease recurrence time and enhance treatment effect. 2017 Vol. 24 (25): 42-44 [Abstract] ( 194 ) HTML (1 KB)  PDF (553 KB)  ( 105 ) 45 Influence of repetitive transcranial magnetic stimulation on central motor conduction function in patients with stroke LIN Min-ting, LI Ming, YANG Xuan, ZHOU Xue-xian Objective To investigate the influence of repetitive transcranial magnetic stimulation on central motor conduction function in patients with stroke.Methods 60 inpatients with cerebral infarction treated in neurology department of our hospital from January 2015 to June 2016 were selected.The patients were randomly divided into group A and group B,and there were 30 cases in each group.Group A was treated with conventional therapy while group B was treated with conventional therapy+rTMS treatment.The patients were detected with triple magnetic stimulation (TST) and neurological function score was compared before treatment and after 10 days treatment.Results The amplitude and area ratio of TSTtest/TSTcontrol decreased in different level in the two groups after ipsilateral treatment,and the decrease of group B was more significant (P<0.05).NIHSS,BI and FMA score were significantly improved in the two groups after ipsilateral treatment,and the neurological scores of group B improved more significantly (P<0.05).Conclusion TST can be used as an objective evaluation index for the treatment of stroke patients.TMS can reduce the TST test results of stroke patients,improve the central motor conduction dysfunction. 2017 Vol. 24 (25): 45-47 [Abstract] ( 572 ) HTML (1 KB)  PDF (595 KB)  ( 183 ) 48 Clinical effect of Simvastatin in the treatment of chronic subdural hematoma DING Guan-fu Objective To investigate the clinical effect of Simvastatin in the treatment of chronic subdural hematoma.Methods 42 patients with chronic subdural hematoma were collected from Februray 2016 to February 2017.The patients were divided into treatment group and control group according to the principle of randomization grouping and there were 21 cases in each group.The treatment group was treated with Simvastatin and the control group was not given Simvastatin.The patients were followed up for 3 months.The hematopoietic volume of the patients was calculated by modified Tada formula.The recovery of neurological function was evaluated by Markwalder classification.After 3 months treatment,the occurrence of hematoma recurrence and treatment efficiency were recorded.Results The effective rate (90.48%) in the treatment group was significantly higher than those of the control group (61.90%),and the difference was statistically significant (P<0.05).Conclusion Clinical effect of Simvastatin in the treatment of chronic subdural hematoma is good therapeutic,and has a positive effect on the recovery of neurological function. 2017 Vol. 24 (25): 48-50 [Abstract] ( 340 ) HTML (1 KB)  PDF (550 KB)  ( 172 ) 51 Effect analysis of early hyperbaric oxygen comprehensive therapy in patients with severe craniocerebral trauma XIE Guan-sheng, CHEN Dong-liang, ZHANG Ji-yuan, ZHANG Song Objective To discuss the effect of early hyperbaric oxygen comprehensive treatment in patients with severe craniocerebral trauma.Methods Fifty-five patients with severe craniocerebral trauma treated in our hospital from April 2015 to April 2017 were selected as observation group for study.They were provided with early hyperbaric oxygen comprehensive therapy.Another group of 55 patients with severe craniocerebral trauma were classified into control group during the same period.The conventional treatment mode was applied.The therapeutic effect between the two groups was compared.Results The total effective rate was 96.37% in the observation group,and it was obviously higher than that of the control group (81.82%) (P<0.05).The score of GCS and ADL before and after treatment were displayed statistical differences in two groups (P<0.05).The score of GCS and ADL after therapy in the observation group were better than those in the control group with statistical differences (P<0.05).Conclusion For patients with severe craniocerebral trauma,effect of early hyperbaric oxygen comprehensive therapy is remarkable by improving patients′ quality of life.It is an optimal treatment mode and is worthy of implementation and promotion. 2017 Vol. 24 (25): 51-53 [Abstract] ( 251 ) HTML (1 KB)  PDF (544 KB)  ( 144 ) 53 The clinical effect of intensive Atorvastatin Calcium Tablets in treatment of acute cerebral infarction WEI Biao-song, LI Tao Objective To explore the clinical effect of intensive Atorvastatin Calcium Tablets in treatment of acute cerebral infarction.Methods 92 inpatients with acute cerebral infarction treated in department from May 2013 to June 2015 were collected and they were randomly divided into the observation group and control group,and there were 46 cases in each group.On the basis of routine treatment,the observation group was treated with 40 mg Atorvastatin Calcium Tablets and the control group was treated with 20 mg Atorvastatin Calcium Tablets.Clinical effect was evaluated by the change of NIHSS after treating.Results C-reactive protein,LDL-C and TC level were obviously decreased in two groups after 14 days and 3 months treatment compared with before treatment,and the decline level in the observation group was significantly higher than that of the control group,and there was a statistical difference (P<0.05).HDL-C level were increased in two groups after treatment,and the elevated level in the observation group was higher than that of the control group,and there was a statistical difference (P<0.05).NIHSS score of the observation group was lower than that of the control group after 1,3,6,12 months,and there was a statistical difference (P<0.05).The total effective rate of the observation group (95.65%) was higher than that of the control group (78.26%),and there was a statistical difference (P<0.05).The incidence of adverse reactions was 10.87% in the observation group and it was 13.04% in the control group,and there was no significant difference between the two groups (P>0.05).Conclusion The effect of intensive Atorvastatin Calcium Tablets in treatment of acute cerebral infarction is exact and it can reduce inflammation,rapidly drop the blood lipid level and improve the prognosis.It is worthy of clinical promotion and application. 2017 Vol. 24 (25): 53-56 [Abstract] ( 266 ) HTML (1 KB)  PDF (607 KB)  ( 125 ) 57 Relation between CT imaging characteristics,intracranial pressure and prognosis after moderate and severe craniocerebral injury LI Jin-liang Objective To investigate the relation between CT imaging characteristics,intracranial pressure and prognosis after moderate and severe craniocerebral injury.Methods 50 patients with moderate and severe craniocerebral injury treated in our hospital from March 2016 to March 2017 were selected as study objects.Head CT scan and intracranial pressure examination were performed,at the same time,the CT imaging characteristics and intracranial pressure were recorded.After the Rotterdam CT score,statistical analysis was performed on the above factors.Results There was a significant correlation between Rotterdam CT score,intraventricular compression,midline shift,basal cistern and intracranial pressure (r=0.838,0.573,-0.624,0.569,P=0.000,0.000,0.000,0.000).The difference between good prognosis group and poor prognosis group in intracranial pressure for 24 h,Rotterdam CT score and basal cistern was statistically significant (P<0.05),and ventricular compression and midline shift between the two groups showed no statistically significant difference (P>0.05).Conclusion In terms of prognosis and intracranial pressure in patients with moderate to severe craniocerebral injury,intracranial pressure and prognosis of patients with moderate and severe craniocerebral injury are negatively correlated.Rotterdam CT score is significantly higher than that of single CT imaging characteristics.The intracranial pressure of patients with moderate and severe craniocerebral injury should be measured and the implementation of relevant treatment measures should be given at the same time,which is helpful to improve the prognosis of patients. 2017 Vol. 24 (25): 57-59 [Abstract] ( 259 ) HTML (1 KB)  PDF (592 KB)  ( 263 ) 60 Effect comparison of traction combined with joint mobilization and traction combined with intermediate frequency electrotherapy in the treatment of cervical spondylotic radiculopathy ZHU Zhi-wen, YIN De-ming, FANG Xiang-yan, LI Zhi-qiang Objective To discuss the application effect of traction combined with joint mobilization and combined with intermediate frequency electrotherapy in the treatment of cervical spondylotic radiculopathy.Methods 100 patients with cervical spondylotic myelopathy admitted into our hospital from May 2014 to May 2016 were selected as study objects.The patients were divided into the control group and the intervention group according to the randomization method,and there were 50 cases in each group.The control group was given traction supplemented by intermediate frequency electrotherapy,and the intervention group was given traction combined with joint mobilization.The visual analogue scale (VAS) was used to assess the improvement of pain before and after intervention in both groups,and the clinical efficacy between the two groups was compared.Results VAS scores of the two groups were significantly improved after the intervention,and the difference was statistically significant (P<0.05),VAS score in the intervention group after the intervention was better than that in the control group after intervention,and the difference was statistically significant (P<0.05).The clinical effect in the intervention group was significantly better than that in the control group,and the difference was statistically significant (P<0.05).Conclusion Traction combined with intermediate frequency electrotherapy and traction combined with joint mobilization both can effectively cure cervical spondylotic radiculopathy,while the latter has a more significant effect,which can effectively relieve the symptoms of nerve root compression,and can be widely promoted and applied in primary hospital. 2017 Vol. 24 (25): 60-62 [Abstract] ( 243 ) HTML (1 KB)  PDF (585 KB)  ( 93 ) 63 Brief discussion of influence of body temperature irrigation fluid on body temperature and blood loss in patients with percutaneous nephrolithotripsy HU Xian-mei Objective To investigate the influence of body temperature irrigation fluid on vital signs in patients with percutaneous nephrolithotripsy.Methods 60 patients undergone percutaneous nephrolithotripsy in our hospital from January 2016 to January 2017 were selected.According to different therapeutic methods,they were evenly divided into control group(irrigation by room temperature fluid) and observation group(irrigation by body temperature fluid).The therapeutic effect in the two groups was compared.Results In the observation group,the temperature was (36.75±0.45)℃ 20 minutes at the beginning of the surgery and (36.46±0.46)℃ at 30 minutes of the surgery,which were much higher than those in the control group (36.11±0.22)℃ and (35.94±0.33)℃ at the 20 and 30 minutes at the beginning of the surgery,respectively.After inter-group comparison,there was a statistical difference(P<0.05).The heart rate (HR) and mean arterial pressure(MAP) during surgery were (86.32±8.25) times/min and (92.35±5.69) mmHg,after surgery,they were (83.01±5.36) times/min and(89.25±.21) mmHg.The above-mentioned indexes in the observation group were greatly lower than those in the control group [intraoperative:(96.24±11.20)time/min,(92.35±5.69)mmHg;postoperation:(99.36±9.24)time/min,(99.36±10.25)mmHg],with statistical differences(P<0.05).In the observation group,the blood loss was (39.62±9.68) ml and the incidence of adverse reactions was (13.34%),while in the control group,they were (64.21±21.36) ml and (43.33%)respectively,with statistical differences(P<0.05).Conclusion Application of body temperature irrigation fluid during surgery not only improve the healing,but also obtain high safety,which is worthy of clinical promotion. 2017 Vol. 24 (25): 63-65 [Abstract] ( 228 ) HTML (1 KB)  PDF (424 KB)  ( 80 ) 66 Application effect analysis of transurethral prostatectomy in the treatment of high risk benign prostatic hyperplasia YANG Ya-han Objective To evaluate the clinical efficacy of transurethral prostatectomy in the treatment of high risk benign prostatic hyperplasia(BPH).Methods From October 2015 to September 2016,39 patients with high risk BPH admitted into our hospital were selected as research objects.All participants were performed with transurethral prostatectomy.The operation time,catheterization time after surgery,incidence of postoperative complications,and hospital stay after surgery were calculated.The international prostate symptom score(IPSS) and quality of life(GQOL-74) before surgery and 3-month follow-up visits after surgery were compared.Results Among 39 patients,the average surgical time,average catheterization time after surgery,incidence of postoperative complications,and average hospital stay after surgery were (21.9±4.6) min,(5.8±1.3) d,(5.1%) and (6.9±1.5) d in turn.The IPSS score 3-month after surgery was (9.6±1.5) points lower than that before surgery,(24.9±2.8) points.The GQOL-74 score was (70.1±5.8) points,higher than that before surgery [(49.5±6.2) points] (P<0.05).Conclusion Application of transurethral prostatectomy in the treatment of high BPH can effectively improve patient′s quality of life with the advantages of short operation time,reliable effect,and few complications. 2017 Vol. 24 (25): 66-68 [Abstract] ( 247 ) HTML (1 KB)  PDF (423 KB)  ( 121 ) 69 The effect of single-channel minimally invasive percutaneous nephrolithotomy and electronic ureteral soft mirror in the treatment of complex renal calculi WAN Bin, ZHANG Wen-sheng, YANG Shao-hong Objective To observe the effect of single-channel minimally invasive percutaneous nephrolithotomy and ureter soft mirror in the treatment of complex renal calculi.Methods 117 patients with complicated renal calculi treated in our hospital from March 2012 to November 2016 were selected as the subjects,and the patients were divided into control group (64 cases) and study group (53 cases).The control group was treated with single-channel minimally invasive percutaneous nephrolithotomy,and the study group was treated with ureteral softening.The operation time,hemoglobin loss,hospitalization time,disposable stone clearance rate,Ⅱ reoperation rate and complications occurred of the two groups were compared.Results There was no significant difference in the operation time between the two groups (P>0.05).The hemoglobin loss of the study group was lower than that of the control group,the hospitalization time was shorter than that of the control group (P<0.05),disposable stone clearance rate in the study group (37.74%) was lower than that in the control group (70.31%) (P<0.05).The complication rate of the study group was 9.43%,which was lower than that of the control group (25.00%) (P<0.05).Conclusion The effect of electron ureteral soft mirror in the treatment of complex renal calculi is more remarkable than that of single channel minimally invasive percutaneous nephrolithy,which is worthy of further application in clinical practice. 2017 Vol. 24 (25): 69-71 [Abstract] ( 388 ) HTML (1 KB)  PDF (426 KB)  ( 83 ) 72 Clinical effect of anterior transection on Gartland type Ⅲ supracondylar fracture of humerus in children ZHANG Xue-lai, XU Yong-wu, REN De-sheng, LI Ming Objective To analyze the clinical effect of anterior transection in the treatment of Gartland type Ⅲ supracondylar fracture of humerus.Methods 54 children with Gartland Ⅲ type supracondylar fractures were selected from March 2014 to March 2017 in our hospital.The patients were divided into control group and treatment group according to the random number table method,each group was 27 cases.The patients in the control group were treated with open reduction and Kirschner wire fixation.The treatment group was treated with anterior and lateral condylar Kirschner wire fixation.The difference was statistically significant between the two groups.Results The excellent rate of elbow function in the treatment group was significantly higher than that in the control group (P<0.05).The incidence of complications in the treatment group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion The transverse incision approach of the elbow can significantly improve the function of the Gartland Ⅲ type supracondylar fracture of the humerus and improve the therapeutic effect,and the incidence of complications is low,which is worthy of clinical preference and popularization and application. 2017 Vol. 24 (25): 72-74 [Abstract] ( 196 ) HTML (1 KB)  PDF (485 KB)  ( 126 ) 75 Study of clinical effect of manipulative reduction,splint external fixation and open reduction and internal fixation in treatment of distal radius C-type fracture in elderly patients ZENG Xing Objective To analyze the clinical effects of manipulative reduction,splint external fixation and open reduction and internal fixation(ORIF) in treatment of distal radius C-type fracture in elderly patients.Methods Altogether 80 cases of senile patients with distal radius C-type fracture who were treated from January 2015 to December 2016 in our hospital were divided into two groups according to the different treatment methods;40 cases in non-surgery group were treated with closed reduction and small splint fixation;40 cases in surgery group were treated with open reduction and plate internal fixation.The clinical effects of the two groups were compared.Results The Cooney wrist score and pain VAS(visual analogue score) of fracture recovery of non-surgery group and surgery group were compared,the difference was statistically significant（P<0.05）;the palm inclination angle and ulnar deviation angle of surgery group were higher than those of non-surgery group （P<0.05）;complications were compared between the two groups,and had no statistial significance （P>0.05）.Conclusion Manipulative reduction,splint external fixation and ORIF can be used in the treatment of intra-articular fractures of the distal radius for elderly patients;but for patients with C-type fracture,the anatomical reduction degree after closed reduction and splint external fixation is far less than ORIF;the appropriate therapy should be selected for treatment of fractures based on the clinical conditions. 2017 Vol. 24 (25): 75-77 [Abstract] ( 233 ) HTML (1 KB)  PDF (487 KB)  ( 132 ) 78 Observation of the clinical effect of percutaneous endoscopic lumbar discectomy for treating lumbar disc herniation WANG Guo-hui, PAN Jin, YANG Yan, MAO Yu-juan, Ai Yan-dong, HUA De-liang, SONG Bin, QING Wei-long, YANG Ji-fei Objective To observe the clinical short-term efficacy of percutaneous endoscopic lumbar discectomy(PTED) in the treatment of lumbar disc herniation.Methods 36 patients with single-segment lumbar disc herniation diagnosed were follow-up observation during from 2014 to December 2016 in our hospital treated by percutaneous lumbar intervertebral disc surgery were followed up and observed.The surgical method was evaluated by VAS scoring system and modified MacNab curative effect evaluation standard.Results 1 day and 3 months after the operation,the VAS scores were (2.53±0.56) and (1.33±0.59)scores,which was lower than that of preoperative (8.62±0.68) with significant differences (P<0.05).According to modified MacNab efficacy evaluation results：excellent in 22 cases,good in 11 cases,medium in 1 cases,poor in 2 cases.Conclusion The treatment of lumbar disc herniation with intervertebral foramen microscopically with excision of nucleus pulposus has the advantages of small injury,less bleeding and lower incidence of complication,the short-term effect is exact. 2017 Vol. 24 (25): 78-81 [Abstract] ( 266 ) HTML (1 KB)  PDF (514 KB)  ( 161 ) 81 Clinical observation of Huayujiegu Powder combined with closed reduction and splint external fixation in treatment of distal radius fracture LIU Dong-sheng, HU Xiao-yi, ZHANG Ying-ying, LIU Zhong-yue, HUANG Zeng-rong, YUAN Chang Objective To study the effect of Huayujiegu Powder combined with closed reduction and splint external fixation in the treatment of distal radius fracture.Methods 60 patients with distal radius fractures from July 2016 to July 2017 in our hospital were selected,according to random number method they were divided into the experimental group and control group,with 30 patients in each group.The control group was treated with external plaster fixation,the observation group was treated with Huayujiegu Powder combined with closed reduction and splint external fixation,the swelling,pain and efficient of patients in two groups were compared.Results The swelling and pain of the observation group was less than that of the control group(P<0.05).The total effective rate was 96.67% in the observation group,83.33% in the control group,the observation group was significantly higher than the control group (P<0.05).Conclusion Huayujiegu Powder combined with closed reduction and splint external fixation for the treatment of distal radius fracture can effectively alleviating pain,reduce swelling and accelerate the healing time,has a good clinical effect,it is worth the clinical opplication. 2017 Vol. 24 (25): 81-83 [Abstract] ( 206 ) HTML (1 KB)  PDF (490 KB)  ( 100 ) 84 Effect of delivery ball movement combined with free position midwifery on labor progress and pregnancy outcome ZHU Xiao-ling Objective To observe and compare the effect of delivery ball movement combined with free position midwifery on labor progress and pregnancy outcome.Methods 200 pregnant women with delivery in the obstetrical department of hospital from December 2015 to December 2016 were selected,and they were divided into observation group and control group according to random number table,with 100 cases in each group.The control group had delivery with traditional semi-reclining position,while the observation group took delivery ball movement combined with free position midwifery.The labor progress and pregnancy outcome were compared between the two groups.Results The time of the first stage of labor,the second stage of labor,the third stage of labor,total stage of labor in the observation group were （256.12±50.12）,（36.01±15.37）,（16.14±4.11）,（301.11±70.01） min,which were less than (401.24±65.79),(47.13±25.11),(26.41±6.67),(482.14±94.57) min in the control group,the differences were statistically significant (P<0.05);the incidence of vaginal delivery (75%) in the observation group was higher than that in the control group (43%),while the cesarean section rate in the observation group (19%) was lower than that in the control group (49%),the differences were statistically significant (P<0.05);the incidence of postpartum hemorrhage,neonatal asphyxia,aspiration syndrome,respiratory disorders in the observation group (1%,1%,2%,1%) were lower than those in the control group (8%,8%,9%,10%),the differences were statistically significant (P<0.05).Conclusion Delivery ball movement combined with free position midwifery can effectively accelerate the stage of labor,improve pregnancy outcome,increase the rate of natural delivery. 2017 Vol. 24 (25): 84-86 [Abstract] ( 210 ) HTML (1 KB)  PDF (608 KB)  ( 143 ) 87 Relationship between suturing method of uterine incision after cesarean section and uterine incision diverticula ZHANG Gui-lian, HU Li-qin, LIU Qing, LUO Ling Objective To analyze the relationship between different suturing method of uterine incision after cesarean section and uterine incision diverticula.Methods 88 patients who were given cesarean section in the Department of Obstetrics in our hospital from September 2014 to September 2016 were selected.The patients were divided into control group and study group according to the random number table,44 cases in each group.The control group was given single-layer continuous suture to implement uterine incision suturing.The study group was given absorbable line at the first layer to continuous suture the inner one third part of myometrium.Absorbable line at the second layer was used to mattress suture the outer one third part of myometrium;the third layer was used to continuously suture bladder reflex.The second layer was not used to suture bladder reflex.The number of cases with uterine incision diverticula,the satisfaction rate of incision suture protocol,the time of postoperative anal exhaust,the duration of postoperative lochia,the total time of postoperative hospitalization,and the improvement of hemoglobin level in different time periods after delivery were compared between the two groups.Results Only one case （2.3%） in the study group formed uterine incision diverticula after the surgery of cesarean section,less than 7 cases in the control group （15.9%）,and the difference between groups was significant （P<0.05）;the satisfaction rate of cesarean section incision protocol was 95.5%,which was higher than that of 77.3% in the control group,the difference between groups was significant （P<0.05）;the duration of postoperative anal exhaust,duration of postoperative lochia and total time of postoperative hospitalization were shorter than those in control group,the differences between groups were significant （P<0.05）;the improvement of hemoglobin level in different time periods after the surgery was higher than that in the control group,and the difference was significant （P<0.05）.Conclusion Three-layer continuous suture is applied to suture the incision for the puerpera after cesarean section,which is effective to reduce the incidence of uterine incision diverticulum,shorten the postoperative recovery time and ensure the safety of puerpera during perinatal period. 2017 Vol. 24 (25): 87-89 [Abstract] ( 246 ) HTML (1 KB)  PDF (611 KB)  ( 160 ) 90 Effect comparison of Mirena and Marvelon in the prevention of endometrial polyp recurrence after TCRP WANG Yuan Objective To compare the effect of levonorgestrel-releasing intrauterine system (trade name:Mirena) and Desogestrel and Ethinylestradiol Tablets (trade name:Marvelon) on the prevention of the recurrence of endometrial polyps after TCRP.Methods From January 2014 to January 2016,180 patients with endometrial polyps treated by TCRP in our hospital were selected and divided into observation group (Mirena placement,n=90) and control group (oral administration of Marvelon for 3 to 6 months,n=90) in random number table.The changes of menstrual blood volume after surgery,endometrial thickness,and endometrial polyp recurrence were observed and compared in the two groups.Results 6- and 12-month after treatment,the menstrual blood volume and recurrence rate in the observation group were (46.07±15.79) ml,(26.97±10.35) ml,and 1.11% respectively,was significantly lower than that in the control group [(71.12±19.27) ml,(85.72±20.28) ml,14.44%],the difference was statistically significant (P<0.05).After 6-month therapy,there was no significant difference in the thickness of endometrium between the two groups (P>0.05).However,12-month after treatment,the endometrium of the observation group was greatly thinner than that in the control group,the difference was statistically significant (P<0.05).Conclusion Compared with oral administration of Marvelon,application of Mirena can more effectively prevent the recurrence of endometrial polyps after TCRP. 2017 Vol. 24 (25): 90-93 [Abstract] ( 276 ) HTML (1 KB)  PDF (618 KB)  ( 78 ) 94 Analysis on the application effect and complications of midwifery by low position forceps in obstetric delivery SHI Yan Objective To analyze the effect and complications of midwifery by low position forceps in the process of obstetric delivery.Methods 89 puerpera with dystocia of cephalic presentation who were admitted to our hospital from March 2014 to October 2016 were selected as the study subjects.According to different modes of midwifery,the patients were divided into the observation group (n=44) and the control group (n=45).Among them,44 puerpera in the observation group were given midwifery pregnancy by low position forceps.45 puerpera in the control group were given maternal cesarean delivery.The incidence of complications such as postpartum hemorrhage,puerperal infection,soft birth canal injury,as well as the occurrence of neonatal facial abrasions,scalp hematoma and neonatal asphyxia in the two groups of puerpera receiving different modes of midwifery were observed and compared.The length of stay and application of antibiotics of puerpera were compared between the two groups.Results The incidence rate of postpartum hemorrhage,puerperal infection and soft birth canal injury after the surgery in the observation group was significantly lower than that in the control group,the differences were statistically significant (P<0.05);compared with the control group,the incidence rate of neonatal facial abrasion,scalp hematoma and neonatal asphyxia was significantly lower in the observation group than in the control group,the differences were statistically significant (P<0.05);compared with the control group,the length of stay in the observation group was significantly shorter than that in the control group,and the proportion of postpartum antibiotics use was significantly lower than that in the control group,the differences were statistically significant (P<0.05).Conclusion Compared with cesarean section,midwifery by low position forceps can effectively reduce maternal and neonatal postpartum complications,improve the effect of maternal and child prognosis,shorten the hospital stay,reduce the use of antibiotics,and improve the safe delivery,which is worthy of clinical popularization and application. 2017 Vol. 24 (25): 94-96 [Abstract] ( 242 ) HTML (1 KB)  PDF (610 KB)  ( 171 ) 97 Application effect of laparoscopic ovarian cystectomy in patients with ovarian cysts LIU Qin Objective To analyze the application effect of laparoscopic ovarian cystectomy in patients with ovarian cyst.Methods 88 cases of ovarian cyst diseases treated in our hospital from January 2016 to July 2017 were divided into the control group and the treatment group according to the wishes of the patients,44 cases in each group.The control group was treated with conventional conservative drugs,and the observation group was treated with laparoscopic ovarian cystectomy.The improvement of ovarian function function related indicators of patients in the two groups before and after treatment,the level of amplitude,recovery time,hospitalization time,ovarian cyst disease,the total efficiency of treatment,adverse reactions during treatment were compared.Results The improvement of ovarian function related indicators of patients in the observation group before and after treatment was fewer than the control group,with the difference was statistically significant (P<0.05);hospitalization time in the observation group was shorter than the control group,with the difference was statistically significant (P<0.05);the treatment of ovarian cyst disease,the total effective rate in the observation group was 90.9%,higher than 70.5% in the control group,with a difference statistical significance (P<0.05);during the period of treatment,only 2 cases (4.5%) in the observation group had adverse reaction,less than 10 cases in the control group (22.7%),with the difference was statistically significant (P<0.05).Conclusion For patients with ovarian cyst disease,laparoscopic ovarian cyst elimination treatment can reduce the influence on the ovarian function to the maximum extent,reduce perioperative adverse reactions,shorten treatment time,ensure the safety of patients. 2017 Vol. 24 (25): 97-99 [Abstract] ( 189 ) HTML (1 KB)  PDF (608 KB)  ( 97 ) 100 Effect of cervical dilation balloon with oxytocin on induced labor in full-term pregnancy LUO Pei-fen, ZENG Dai-di, LI Zhong-jun Objective To explore the clinical effect of cervical dilatation balloon combined with oxytocin on induction of labor in full-term pregnancy.Methods From June 2015 to December 2016,100 full-term pregnant women with induced labor indications were evenly divided into two groups according to a random number table.Oxytocin was use in 50 pregnant women of the control group for labor induction,while in study group,cervical dilatation balloon combined with oxytocin was used in 50 pregnant women for induction.The induced labor,delivery,labor of stage,neonatal conditions,and complications were compared between the two groups.Results In the study group,the promoted cervical ripening rate was 100.00%,significantly higher than that in the control group accounting for 68.00% (P<0.05).There was no significant difference in Bishop score between the two groups before intervention (P>0.05).The Bishop score of the cervix in the study group was significantly higher than that in the control group after intervention (P<0.05).The time of induced labor in the study group was much shorter than that in the control group with a high success rate of induction and low rate of cesarean section (P<0.05).The time of first stage of labor and total stage of labor in the study group were much shorter compared with those in the control group (P<0.05).There was no significant difference in the second stage of labor (P>0.05).There was no significant difference in the neonatal conditions between the two groups (P>0.05).The complications including pelvic infection,postpartum hemorrhage,cervical laceration,and amniotic fluid in degree Ⅱ were not displayed statistical differences in the two groups (P>0.05).The incidence of amniotic fluid contamination in the study group was higher than that in the control group (P<0.05).Conclusion For full-term pregnancy induction with indications,application of cervical dilation balloon with oxytocin can facilitate cervical ripening,shorten the labor stage,increase the success rate of induced labor,and decrease the rate of cesarean section,which is safe and effective,and is worthy of promotion in clinic. 2017 Vol. 24 (25): 100-103 [Abstract] ( 372 ) HTML (1 KB)  PDF (620 KB)  ( 126 ) 104 Observation of the clinical effect of Kegel exercise combined with postpartum rehabilitation exercise on the prevention of postpartum constipation CHEN Yue-lan, TANG Shi-xiao, MAI Xi-xian Objective To explore the clinical effect of postpartum rehabilitation exercise combined with Kegel exercises for prevention of postpartum constipation.Methods 100 cases of postpartum rehabilitation in Department of Obstetrics and Gynecology of our hospital were selected and randomly divided into two groups by random number table,50 cases each.Patients of the control group were given routine rehabilitation training,the specific content,guide the maternal high leg walking,squat stand,kick movement action and supine leg lift,climbing bicycle movements such as the postpartum health care and abdominal massage in self standing,and the study group were treated more with Kegel exercises on the basis of the control group.Maternal postpartum rehabilitation exercise in the first week and third weeks of defecation frequency,the total effective rate and recurrence were compared.Results Compared with the control group,frequency of defecation in the study group was higher at 1 and 3 weeks after postpartum rehabilitation exercise (P<0.05);the total efficiency of postpartum rehabilitation exercise of the study group was 96%,was higher than 76% of control group,the difference was statistically significant (P<0.05);total recurrence rate of constipation within 120 days after exercise of the study group was 6.00%,was lower than 26.00% of control group,the difference was statistically significant (P<0.05).Conclusion Kegel exercise combined with postpartum rehabilitation exercise can significantly improve the number of maternal defecation, and reduce the recurrence rate,with significant effect,which has guiding significance for clinical and is worth of promoting. 2017 Vol. 24 (25): 104-106 [Abstract] ( 210 ) HTML (1 KB)  PDF (614 KB)  ( 122 ) 107 Effect observation on bronchoalveolar lavage in the treatment of severe Mycoplasma pneumonia in children under fiber bronchoscope LIU Qing-biao, LUO Hui-chang, XU Bo-hua, LI Shi-yu, ZHANG Yu-ling Objective To explore the application value of bronchoalveolar lavage in the treatment of severe Mycoplasma pneumonia in children under fiber bronchoscope.Methods A total of 100 pediatric patients who were diagnosed with severe Mycoplasmal pneumonia by X-ray,CT and laboratory indicators in our hospital from January 2015 to December 2016 were selected as research objects.The etiology was exclusively due to inflammation by fiber bronchoscope ruling out of foreign substance,deformity,tumor,and nodule.According to different therapeutic methods,they were divided into two groups.Regular applications of ventilator-assisted respiration,anti-infection,nutritional support,and symptomatic treatment were provided in both groups.In observation group(n=50),bedside sputum suction by fiber bronchoscope,lavage,and drug injection were provided,while in control group(n=50),sputum suction tube and humidifying for treatment were adopted.The effect and safety in the two groups were observed.Results The therapeutic effective rate was 96.0% in the observation group and 76.0% in the control group,with a statistical difference between the two groups (P<0.05).In comparison with the cough,chest pain,lung rale,and time of X-ray absorption in the lung,those in the observation group were much shorter than those in the control group,which were displayed statistical differences(P<0.01).In the observation group,2 cases were occurred with the complications,including 1 case of nasal bleeding and 1 case of postoperative fever,accounting for 4.0% in all.The complications were improved after symptomatic treatment.No complications occurred in the control group,which was not displayed a statistical difference after comparison.Conclusion Under fiber bronchoscope,bronchoalveolar lavage has a remarkable effect on severe mycoplasma pneumonia in children,which is safe and effective. 2017 Vol. 24 (25): 107-109 [Abstract] ( 215 ) HTML (1 KB)  PDF (645 KB)  ( 148 ) 110 Analysis of risk factors of intrauterine growth retardation YANG Xiao Objective To explore the risk factors of intrauterine growth retardation so as to provide guidance for clinical practice.Methods 200 cases of pregnant women in our hospital from October 20th 2014 to October 20th 2016 were selected as the subjects of this study.The clinical data of pregnant women were retrospectively analyzed.Among them,39 cases of pregnant women were diagnosed of intrauterine growth retardation (experimental group),and 161 cases of pregnant women were in normal intrauterine development (control group).The risk factors for intrauterine growth retardation were investigated.Results There were significant differences in pre-pregnancy weight,gestational age,pregnancy complications,adverse living habits,microbial infection,gene mutation,placenta previa and placental abruption between the experimental group and the control group (P<0.05);according to Logistic regression analysis of intrauterine growth retardation,the pre-pregnancy weight,gestational age,pregnancy complications,adverse living habits,microbial infection,gene mutation,placenta previa and placental abruption were risk factors leading to intrauterine growth retardation (P<0.05).Conclusion Excessively low pre-pregnancy weight,excessive high gestational age,pregnancy complications,adverse living habits,microbial infection,gene mutation,placenta previa and placental abruption are risk factors leading to intrauterine growth retardation. 2017 Vol. 24 (25): 110-112 [Abstract] ( 202 ) HTML (1 KB)  PDF (613 KB)  ( 120 ) 113 Analysis of depression after stroke in patients with brain function default network connectivity rs-fMRI LIU Wen-hong, LUO Guang-hua, ZHAO Heng, LIU Jing-cai Objective To study the change of brain network connectivity in patients with poststroke depression using resting multifunctional magnetic resonance imaging (rs-fMRI).Methods From February 2016 to February 2017,30 patients with post-stroke depression were selected as observation group,30 patients with no depression after the same period were selected as the control group.Basic information on patients,the daily life activity score before treatment,4 weeks after treatment and 12 weeks after treatment were compared between the two groups.In addition,all patients were examined by rs-fMRI technique.The bilateral anterior wedge was selected as the region of interest,and the changes of the default network function were calculated and compared.Results The scores of NIHSS in the observation group were (11.1±5.3)points,which was significantly higher than that of the control group[(6.7±2.9)points].The ADLS score of the observation group was (40.2±15.6)points at 4 weeks after treatment and 12 weeks after treatment[(29.2±12.7) points] were significantly higher than those in the control group [(32.1±13.9),(21.5±10.4) points].Compared with the control group,the connection of the right lower lobe,bilateral frontal temporal lobe and left anterior lobe of the anterior fissure was decreased.The bilateral lobular,bilateral frontal temporal lobe and right anterior lobe anterior lobe were decreased functional linkage was significantly higher in the brain area than that in the control group.Conclusion There is a close relation with the occurrence of post-stroke depression and the change of the default network function connection,it is worth focusing on attention. 2017 Vol. 24 (25): 113-116 [Abstract] ( 258 ) HTML (1 KB)  PDF (383 KB)  ( 109 ) 116 Application of magnetic resonance imaging in the evaluation of pulmonary hypertension XU Yan, LUO Xin, LIU Li-qiong, HU Liang-liang Objective To study the value of magnetic resonance imaging(MRI) in the evaluation of pulmonary hypertension (PAH).Methods 60 cases of PAH patients from September 2014 to March 2017 in our hospital were seleted as experimental research object,12 healthy volunteers were seleted as control group.All subjects were performed MRI and right cardiac catheterization examination.The correlation of MRI anatomy and right cardiac catheterization detection indicators were analyzed.Results The Pearson correlation analysis showed that the main pulmonary artery diameter/right across the top plane of the chest diameter (MPA/T),right ventricular anterior wall thickness /right across the top plane of the chest diameter(RVW/T) and pulmonary artery collection was correlated with systolic pressure,average pressure and total pulmonary resistance (P<0.01),the right pulmonary artery diameter (RPA) pressure and mean pressure was correlated with pulmonary artery systolic (P<0.05).Conclusion The anatomic indexes of MPA/T MRI,RVW/T can be used to determine the degree of pulmonary hypertension and quantitative analysis of pulmonary hypertension. 2017 Vol. 24 (25): 116-118 [Abstract] ( 220 ) HTML (1 KB)  PDF (421 KB)  ( 80 ) 119 The clinical curative effect of Vinpocetine combined with Shuxuetong Injection in treatment of acute cerebral infarction ZHANG Xiao-xia Objective To investigate the clinical effect of Vinpocetine combined with Shuxuetong Injection in treatment of acute cerebral infarction.Methods 86 cases of patients with acute cerebral infarction admitted in our hospital from January 2015 to January 2016 were selected as the study subjects.They were divided into study group and control group according to different treatment methods,each group of 43 cases.The patients in two groups were treated with oxygen inhalation,maintenance of vital signs,Aspirin oral,intravenous input of brain cell nutrition,blood lipid-lowering drug and other symptomatic and supportive treatment.The patients in the study group were given Vinpocetine 20 mg joined in 0.9% Sodium Chloride Injection 250 ml intravenous drip,1 time a day,Shuxuetong Injection 6 ml joined in 5% Glucose Injection 250 ml intravenous drip,1 time a day,the course of treatment was 14 days.The patients in the control group were treated with Citicoline 0.75 g joined in 0.9% Sodium Chloride Injection 250 ml intravenous drip,Fufang Danshen injection 20 ml joined in 5% Glucose Injection 250 ml intravenous drip,1 time a day,the course of treatment was 14 days.The clinical efficacy of the two groups were compared,the changes of NIHSS and ADL scores before and after treatment in the two groups were also compared.Results After treatment,the total effective rate of patients in the study group (97.6%) was higher than that in the control group (76.7%),and the difference was statistically significant (P<0.05).NIHSS and ADL scores were compared in the two groups before treatment,and the differences were not statistically significant (P>0.05).After treatment,the ADL score of the patients in the study group was significantly higher than that in the control group,the NIHSS score was significantly lower than that in the control group,and the differences were statistically significant (P<0.05).Conclusion Vinpocetine combined with Shuxuetong Injection in the treatment of acute cerebral infarction can significantly improve the neurological function and the life quality of patients.It is worthy of clinical popularization and application. 2017 Vol. 24 (25): 119-121 [Abstract] ( 246 ) HTML (1 KB)  PDF (385 KB)  ( 127 ) 122 The efficacy and safety of Fluoxetine combined with low-dose Risperidone in the treatment of refractory depression CHEN Jian-feng, ZHANG Mei-hu, YUAN Wei-ming Objective To investigate the efficacy and safety of Fluoxetine combined with low-dose Risperidone in the treatment of refractory depression.Methods From July 2012 to July 2016,70 patients with refractory depression in our hospital were selected as subjects.The patients were randomly divided into two groups,each with 35 cases.The control group was treated with Fluoxetine and the observation group was treated with low-dose Risperidone (0.5-2.0 mg/d),continuous use for 12 weeks.The HAMD depression scores,CGI-SI curative effect evaluation and side effects score of patients in two groups were compared.Results The HAMD score and CGI-SI score of the observation group were lower than those of the control group at the end of 4,8 and 12 weeks after trestment,and the differences were statistically significant (P<0.01).The score of side effects in the observation group at the end of 12 weeks were compared with the control group,and the difference was not statistically significant (P>0.05).Conclusion Combination therapy of FLuoxetine and low-dose Risperidone can improve the therapeutic effect,promote the remission of symptoms such as depression,control the diseaseand high safety,it is worth promoting. 2017 Vol. 24 (25): 122-124 [Abstract] ( 271 ) HTML (1 KB)  PDF (384 KB)  ( 124 ) 125 Study on quality standard of sugarless Waiganfengsha Granules LUO Yu-dong, LU Shi-heng, TAN An-qiang, WU Yu-qiang, CHEN Hong-tao Objective To set up the quality control standard of sugarless Waiganfengsha Granules.Methods Thin layer chromatography (TLC) was used,and petroleum ether (60-90℃)-ethyl acetate-glacial acetic acid (16:2:1) was the developing agent,and 10% sulfuric acid ethanol solution selected as the chromogenic agent to qualitatively identify Streptocaulon griffithii.Toluene-ethyl acetate-glacial acetic acid (10:3:1) was the developing agent,and it was observed under ultraviolet lamp (365 nm) to qualitatively identify Holly root.HPLC was used,chromatographic column:Shimadzu C18 chromatographic column (4.6 mm×150 mm,5 μm) was adopted,and mobile phase:acetonitrile-0.4% phosphoric acid solution (13:87),current speed:0.5 ml/min,and column temperature:25℃,detection wavelength was 327 nm,sample size:10 μl,and sampling time was 60 min.The content of chlorogenic acid in the product was determined.Results According to TLC method,in test sample chromatography,in the corresponding position with Streptocaulon griffithii chromatogram of contrast medicinal material,1 or more than 1 spots in same color were displayed while in the corresponding position with Holly root chromatogram of contrast medicinal material 1 or more than 1 bright spots in same color were displayed,and the spots were clear,and the specificity was strong with good reproducibility,and it had no interference of negative.Chlorogenic acid had a good linear relationship with peak area in the range of 6.2968-201.5 μg (r=0.9991) of sample size,and the average recovery rate was 100.11%,and RSD was 0.14% (n=6).The average content of Chlorogenic acid was 1.1069 mg/g (RSD=0.45 %) among 10 batches of sample tablets.Conclusion The quality control method used has a characteristics of sensitive method,strong specificity,good reproducible and high stability,and it can be used as the quality standard control method of sugarless Waiganfengsha Granules. 2017 Vol. 24 (25): 125-129 [Abstract] ( 214 ) HTML (1 KB)  PDF (630 KB)  ( 149 ) 130 Comparison of antibacterial activities of different ethanol extracts from Gentianae Macrophyllae Radix LI Jun, WANG Hong-yan, ZHANG Ran, HAO Cai-qin Objective To analyze the in vitro antimicrobial activities of different ethanol extracts from Gentianae Macrophyllae Radix to Staphylococcus aureus,Staphylococcus epidermidis,Enterococcus faecalis and Shigella flexneri.Methods Oxford cup method and two fold dilution test tube combined with agar plate method were used to determine the antibacterial activities in vitro and minimal inhibitory concentration (MIC) of different extracts with ethanol,65% ethanol and water as solvent of Gentianae Macrophyllae Radix on four kinds of bacteria.Results Three kinds of ethanol extracts of Gentianae Macrophyllae Radi had certain antibacterial effects on bacteria,and the 65% ethanol extract was the best one,which antibacterial activities to Enterococcus faecium and Staphylococcus epidermidis were stronger and MIC was 7.83 g/L and 15.63g/L separately.MIC of Staphylococcus aureus was 62.50 g/L.Conclusion 65% extracts of Gentianae Macrophyllae Radi have a stronger antibacterial activity for Enterococcus faecium,Staphylococcus epidermidis and Staphylococcus aureus,which provides the experimental basis for the rational use of this kind of medicinal herbs. 2017 Vol. 24 (25): 130-132 [Abstract] ( 209 ) HTML (1 KB)  PDF (495 KB)  ( 130 ) 133 Effect of acupuncture combined with moxibustion at Naokong acupoint in the treatment of vertebral artery type of cervical spondylosis WEI Li-li, CAO Jun-yong, CHEN Nan-ping, TANG Xiao-min, MA Jiu-li, WEN Jin Objective To investigate the effect of acupuncture combined with moxibustion at Naokong acupoint in treatment of vertebral artery type of cervical spondylosis.Methods 60 patients with vertebral artery type of cervical spondylosis treated in department of rehabilitation of our hospital from June 2016 to June 2017 were selected,and they were randomly divided into two groups and they were treated with acupuncture plus moxibustion therapy (30 cases in observation group) and acupuncture therapy (30 cases in control group) respectively.The clinical effect between the two groups was compared.Results The post-operative average blood flow velocity (Vm) of vertebral artery (VA) and basilar artery (BA) of observation group were significantly higher than those before treatment and higher than those of control group at the same period.The total effective rate of observation group (96.7%) was higher than that of control group (80.0%) with significant difference (P<0.05).Conclusion Acupuncture combined with moxibustion at Naokong acupoint treating vertebral artery type of cervical spondylosis can accelerate the cerebral blood flow velocity and inprove the therapeutic effect. 2017 Vol. 24 (25): 133-135 [Abstract] ( 298 ) HTML (1 KB)  PDF (410 KB)  ( 100 ) 136 Clinical effect of Modified Buyang Huanwu Decoction preventively treating myositis ossificans after elbow injury surgery LI Ying-zhou, YE Feng, YANG Yong-bo, CHEN Yuan-sheng, CHEN Jian-liang Objective To investigate the effect of Modified Buyang Huanwu Decoction preventively treating myositis ossificans after elbow injury surgery.Methods 69 patients with elbow injuries treated in our hospital from August 2012 to March 2016 were selected as the observation object,among them,32 cases accepted the traditional Chinese medicine treatment (Chinese medicine treatment group) while the remaining 37 patients had no medication (control group).All the patients were followed up at post-operative 4 weeks,3 months and 12 months and underwent elbow joint anteroposterior and lateral X-ray examination and serum alkaline phosphatase (ALP).Meanwhile,the elbow function was assessed according to the Mayo Elbow Performance Score (MEPS).Results The average follow-up time of Chinese medicine treatment group was (16.0±3.9) months,X-ray showed 1 case of myositis ossificans (3.2%),and the average follow-up time of the control group was (17.0±2.8) months and the X-ray showed 5 cases of myositis ossificans (14.5%),and the incidence of elbow joint myositis ossificans of control group was significantly higher than the Chinese medicine treatment group (P<0.05).ALP content of Chinese medicine treatment group at post-operative 4 weeks was significantly lower than that of the control group,with statistically significant difference (P<0.05),and ALP content of Chinese medicine treatment group at post-operative 3 months and 12 months had no significant difference compared with that of control group,without no statistical difference (P>0.05).After 3 months and 12 months treatment,elbow joint function score in Chinese medicine treatment group was obviously higher than that of control group,and there was a statistical difference (P<0.05).Conclusion It is safe and effective for the patients with elbow injuries to be treated with traditional Chinese medicine,which plays a certain role in the prevention of elbow myositis ossificans. 2017 Vol. 24 (25): 136-138 [Abstract] ( 210 ) HTML (1 KB)  PDF (416 KB)  ( 158 ) 139 Utilization of healthybirth before pregnancy in the floating population XU Xiao-yan, LYU Nian-qing, ZHA Shu-wei, FU Ya-li, CHENG Yan, XU Hao-qin Objectives To investigate the health knowledge,intention and behavior of floating population before pregnancy in Jiangsu Province.Methods 18 Family planning cadres were deeply interviewed in 3 project sites of the southern,the central and the northern region of Jiangsu during the first half of 2015 on the basis of the survey of 600 floating population.Results Most floating population aged from 20 to 30 years were workers and businessmen,having middle school education to junior college education and living in one place for more than 1 year.They had general knowledge of prenatal and postnatal care,the main channel was network,TV,consulting services and active promotion.The rate of participating in pre-pregnancy health examination was low which showed lack of initiative of floating population,even though they enjoy the same quality services as the permanent residents.Conclusions Floating population is the emphasis and difficulty for promoting the complete coverage of the free pre-pregnancy health examination.To strengthening the research in the pre-pregnancy care of floating population and enhance the education of floating population,so as to promote more floating population to participate in pre-pregnancy health examination. 2017 Vol. 24 (25): 139-142 [Abstract] ( 219 ) HTML (1 KB)  PDF (539 KB)  ( 72 ) 143 Value and function analysis of early exposure to clinical training for medical students' professional accomplishment HUANG Yun-ye, LI Yan-jiao, XU Ping-ping, HUANG Chun Objective To investigate the clinical value and effect of early contact occupation accomplishment of medical students training.Methods From September 2015 to June 2016,615 medical students in our College were selected,and 441 medical students who with early exposure of clinical activity as the experimental group,while 174 cases those without early contact with clinical and only was given the traditional basic theory course of medical students as the control group.The occupation literacy (the understanding of the basic medical procedure of hospital medical work understanding,occupation literacy,master of clinical knowledge and skills and patient communication skills) performance score of medical students in the two groups and the cognition of early clinical exposure of the experimental group before and after the observation were compared,and the clinical activities on the early stage of the contact evaluation of medical students in two groups was observed.Results The occupation literacy score of the experimental group was higher than that of the control group,the difference was statistically significant (P<0.05);the awareness of early exposure to clinical activities,volunteer service of the hospital to understand,the necessity of early clinical contact,the cognition of importance of comprehensive qualities of medical students in experimental group was increased after early clinical contact,the difference was statistically significant (P<0.05);the scores of early clinical activities evaluation of the experimental group was higher than that of the control group,the difference was statistically significant (P<0.05).Conclusion The implementation of early exposure to clinical activities can enhance the awareness of professional knowledge of medical students and improve their clinical thinking ability,and strengthen the interpersonal communication ability,is conducive to the cultivation of medical students' occupation accomplishment,it is worthy of popularization and application. 2017 Vol. 24 (25): 143-145 [Abstract] ( 241 ) HTML (1 KB)  PDF (524 KB)  ( 169 ) 146 Analysis on irrational application of traditional Chinese medicine injection for promoting blood circulation and removing blood stasis in clinical departments of orthopedic hospital CUI Hong-jiang, BAI Lu-lu, DUAN Qiu-xia, ZHOU Jin-wei Objective To analyze the status of traditional Chinese medicine injection of blood circulation and blood stasis in clinical department of orthopedic hospital for the past three years,and to provide reference for promoting clinical rational drug use.Methods Retrospective survey was conducted in the clinical department of the hospital from January 2014 to December 2016,and the clinical data of the hospital were evaluated comprehensively by the number of varieties,sales amount,frequency of drug use and sorting ratio.Results From 2014 to 2016,the number of varieties and annual sales of traditional Chinese medicine injection of blood circulation and blood stasis were decreased year by year.The ranking of sales and the frequency of medication mainly focused on brain surgery,trauma and hand significant surgical;unreasonable number of drugs decreased from 4345 cases to 274 cases.Conclusion The medical institutions should actively adopt the new model of three-level quality control management to carry out gradual standardization of clinical irrational drug use. 2017 Vol. 24 (25): 146-148 [Abstract] ( 210 ) HTML (1 KB)  PDF (485 KB)  ( 158 ) 149 Application effect comprehensive nursing intervention in preventing the complications after ovarian tumor LI Xin-lian, ZHANG Yi-qun Objective To discuss the clinical efficacy of comprehensive nursing intervention in preventing the complications after ovarian tumor.Methods 64 patients given ovarian tumor operation treated in our hospital from January to December 2015 were selected as the research objects,and they were randomly divided into the comprehensive nursing group and the routine nursing group,each group had 32 patients.The comprehensive nursing group was given comprehensive nursing intervention,while the routine nursing group was given routine nursing intervention.The postoperative complications,the improvement of quality of life and the operation time and hospitalization time in patients between the two groups were compared.Results Before nursing,there was no significant difference in the quality of life score between the two groups (P>0.05),after nursing,the improvement of life quality,such as physical function,social function and mental function in patients of the comprehensive care group were significantly better than that of the routine nursing group,and the difference was statistically significant (P<0.05).The average hospitalization time,the average surgery time of the comprehensive group were shorter than those of the conventional nursing group,and the difference was statistically significant (P<0.05).The incidence of postoperative complications in the comprehensive care group was significantly lower than that in the routine nursing group,and the difference was statistically significant (P<0.05).Conclusion Comprehensive nursing intervention can significantly reduce the incidence of complications ovarian neoplasms after operation,it improves the quality of life after surgery for patients,and it shorten the operation time and hospitalization time,the nursing effect is significant,it is worthy of clinical promotion and application. 2017 Vol. 24 (25): 149-151 [Abstract] ( 206 ) HTML (1 KB)  PDF (668 KB)  ( 112 ) 152 Application effect of quality control circle activities on healthy behavior guidance of new hemodialysis patients LI Jing, XU Hui-yu Objective To explore the application effect of quality control circle activities on healthy behavior guidance of new hemodialysis patients.Methods From March to October 2015,92 patients who received new hemodialysis in our hospital were randomly divided into two groups,46 cases in each group.The control group was given routine healthy behavior guidance,and the observation group was given quality control circle activities and healthy behavior guidance.The related knowledge master,compliance and self-care level of patients in the two groups were compared.Results The excellent and good rate of related knowledge master in observation group (93.5%) was higher than that of the control group (76.1%),and the difference was statistically significant (P<0.05).The compliance rate of observation group (91.3%) was higher than the control group (67.4%),and the difference was statistically significant (P<0.05).After the guidance,the adverse health behaviors changed and the self-care level score of the observation group were higher than the control group,and the differences were statistically significant (P<0.05).Conclusion The quality control circle of hemodialysis patients healthy behavior guidance can improve the degree of mastering the knowledge of the patients and compliance,and also reduce the adverse healthy behaviors of patients,improve self-care ability,has good effect. 2017 Vol. 24 (25): 152-154 [Abstract] ( 217 ) HTML (1 KB)  PDF (669 KB)  ( 130 ) 155 Motivational interview on effect of chemotherapy compliance and pain control in patients with advanced cancer WANG Xing-ying, HE Ye Objective To explore the motivational interview on the effect of chemotherapy compliance and pain control in patients with advanced cancer.Methods Altogether 96 patients with advanced cancer who received chemotherapy in our hospital from April 2015 to April 2016 were randomly divided into two groups according to the random number table method,with 48 cases in each group.The control group was received routine chemotherapy care;while the observation group was received motivational interview intervention on the basis of routine care.The chemotherapy compliance and the DRS score of the two groups were compared.The BQ scores were compared between the two groups before and after nursing.Results The good chemotherapy compliance rate of observation group (95.8%) was higher than that of control group (72.9%),and the difference was statistically significant (P<0.05).After nursing,the DRS score of two groups were decreased,but the DRS score of observation group [(2.1±0.3)points] was lower than that of control group [(3.8±0.6)points],and the difference was statistically significant (P<0.05).After nursing,the BQ score of two groups were decreased,but the BQ score of observation group [(1.2±0.3)points] was lower than that of control group [(2.2±0.4)points],and the difference was statistically significant (P<0.05).Conclusion Motivational interview can effectively improve the chemotherapy compliance of patients with advanced cancer,reduce the degree of pain and enhance the self-control level of cancer pain,which is an ideal way of nursing and worthy of clinical application. 2017 Vol. 24 (25): 155-157 [Abstract] ( 197 ) HTML (1 KB)  PDF (669 KB)  ( 62 ) 158 The effect of psychological intervention in the nursing of gastric cancer patients with most gastric excision YU Xiu-yun Objective To explore the effect of psychological intervention in the nursing of gastric cancer patients with with most gastric excision.Methods A total of 90 gastric cancer patients who were performed most gastric excision were selected as the subjects from July 2014 to May 2016 in our hospital.The patients were divided into two groups according to the odevity of patients′ admission number,with 45 cases in each group.The patients in control group were treated with routine nursing,while the patients in observation group were treated with psychological care on the basis of the control group.The psychological status,postoperative complication and quality of life of the two groups were compared.Results The SDS and SAS scores in the observation group were lower than the control group,and the differences were statistically significant (P<0.05).The postoperative complication rate was lower in the observation group than that in the control group,and the difference was statistically significant (P<0.05).The quality of life in the observation group was higher than the control group,and the difference was statistically significant (P<0.05).The average length of hospital stay in the observation group was shorter than the control group,and the difference was statistically significant (P<0.05).Conclusion The psychological intervention was carried out on the gastric cancer patients with most gastric excision basis on the routine nursing care,effect is remarkable,it is beneficial to stabilize the patients′ bad psychology,reduce complications,shorten hospitalization time,improve the quality of life,is worthy of application. 2017 Vol. 24 (25): 158-160 [Abstract] ( 215 ) HTML (1 KB)  PDF (670 KB)  ( 73 ) 161 Effect of clinical nursing intervention on the treatment of pediatric congenital heart disease combined with pneumonia ZHOU Chuan-fang Objective To explore the effect of clinical nursing intervention on the treatment of pediatric congenital heart disease combined with pneumonia.Methods The 65 pediatric CHD patients with pneumonia who were admitted to our hospital from March 2012 to March 2016 were selected as the study subjects,randomly divided into the study group (32 cases) and the control group (33 cases).Both groups were given routine care,the study group was given the regular nursing care and continuous nursing on the basis of routine care.The heart rate recovery time,respiratory stabilization time,pulmonary rales disappeared time,treatment outcome and recurrence after discharge of the pediatric patients in two groups were compared.Results The heart rate recovery time [(1.79±0.81)d],respiratory stabilization time [(1.83±0.36)d] and pulmonary rales disappeared time [(12.41±1.52)d] of pediatric patients in the study group were both shorter than those in the control group [(2.30±0.65),(2.14±0.73),(12.41±1.52)d],and the differences were statistically significant (P<0.05).After treatment,the rehabilitation hospital discharge rate (100.00%) of pediatric patients in the study group was higher than that in the control group (87.879%),recurrence rate in the six months after discharge (9.375%) in the study group was lower than the control group (30.303%),and the differences were statistically significant (P<0.05).Conclusion Clinical nursing intervention has a positive effect on the actual therapeutic effect of CHD children combined with pneumonia,which can promote the normal recovery of heart rate and respiratory index,promote the regression of disease symptoms,accelerate their recovery and reduce the possibility of recurrence. 2017 Vol. 24 (25): 161-163 [Abstract] ( 202 ) HTML (1 KB)  PDF (670 KB)  ( 101 ) 164 The control effect analysis of obstetric infection was analyzed by seamless nursing intervention PEI Jin-xiu Objective To explore the control effect analysis of seamless nursing management on reducing infection in obstetrics and gynecology department.Methods 86 patients treated in the gynecology and obstetrics department in our hospital from January to November 2016 were selected as the study subjects,and the patients were divided into treatment group and control group by random digital table method,with 43 cases in each group.The control group was taken routine nursing care,while the treatment group was given application of seamless nursing intervention.32 nurses in our department were randomly divided into two groups,with 16 nurses in each group.The comprehensive quality of nursing of two groups were compared and were assessed by analyzing the basic knowledge,basic operation and disease knowledge.The satisfaction and incidence of nosocomial infection of patients in two groups were compared.Results The score of basic knowledge,basic operation and disease knowledge in treatment group were higher than the control group,and the differences were statistically significant (P<0.05).In the treatment group,the satisfaction of nursing (93.02%) was significantly higher than that of the control group (86.05%),and the difference was statistically significant (P<0.05).The total infection rate of the patients in the treatment group was lower than the control group,and the difference was statistically significant (P<0.05).Conclusion Seamless nursing management can optimize the nursing link,improve the quality of nursing and the satisfaction of patients,and also effectively reduce the incidence of infection.It is worthy of clinical application. 2017 Vol. 24 (25): 164-166 [Abstract] ( 187 ) HTML (1 KB)  PDF (671 KB)  ( 100 ) 167 Effect of health education implemented by PDCA circulation method on quality of life and pregnancy outcome in pregnant women with hypertensive disorder complicating pregnancy HE Ling-yun Objective To explore the effect of the health education based on PDCA circulation method on quality of life and pregnancy outcome in pregnant women with gestational hypertension.Methods 88 pregnant women with hypertensive disorder complicating pregnancy from July 2015 to September 2016 were selected as the study subjects,the random number table method was used to divide them into two groups,each with 44 cases.The pregnant women in control group were received routine health education,the pregnant women in observation group were received the health education based on PDCA circulation method.The quality scores of life,mental state scores and pregnancy outcome of pregnant women in two groups were compared.Results After nursing,the scores of pregnant women in the two groups were significantly increased,and the observation group was higher than the control group,the difference was statistically significant (P<0.05).The SAS and SDS scores of observation group were lower than the control group after nursing,and the differences were statistically significant (P<0.05).The incidence of preterm labor,premature rupture of membranes,excessive amniotic fluid,cesarean section and neonatal asphyxia in the observation group were significantly lower than those in the control group, and the differences were statistically significant (P<0.05).Conclusion The health education based on PDCA circulation method can effectively improve the quality of life in pregnant women of gestational hypertension,reduce their psychological burden and can improve their pregnancy outcomes,it is worthy of clinical promotion. 2017 Vol. 24 (25): 167-170 [Abstract] ( 246 ) HTML (1 KB)  PDF (717 KB)  ( 89 ) 170 Efficacy of early rehabilitation nursing intervention on reducing disability rate of patients with acute cerebral thrombosis HUANG Miao-shan Objective To explore the efficacy of early rehabilitation nursing intervention on reducing disability rate of patients with acute cerebral thrombosis.Methods 160 patients with acute cerebral thrombosis who were enrolled in our hospital from January 2015 to February 2017 were selected and randomly divided into the observation group and the control group,with 80 cases in each group.The observation group was given early rehabilitation intervention method,wihle the control group was given conventional nursing methods.The neurologic impairment clinical treatment effect,recovery indicators and nursing satisfaction were compared between two groups.Results The total effective of neurologic impairment treatment (97.50%),nursing satisfaction (98.75%),the score of FMA [(90.12±5.88) points] and Barthel [(85.43±7.82) points] were better than those in the control group [87.50%,85.00%,(75.43±9.58) points,(22.45±3.45) d,(64.35±5.78) points],and the differences were statistically significant (P<0.05).Conclusion Early rehabilitation nursing intervention can improve neurological deficit in patients with acute cerebral thrombosis,can restore life and athletic ability and improve patient care satisfaction,which is worthy of clinical promotion. 2017 Vol. 24 (25): 170-173 [Abstract] ( 204 ) HTML (1 KB)  PDF (679 KB)  ( 130 ) 174 Application value of high quality nursing in nursing care of protrusion of lumbar intervertebral disc CHEN Xiao-hong, XIE Wei, XU Li-peng Objective To explore the application value of high quality nursing in nursing care of protrusion of lumbar intervertebral disc.Methods 118 patients with protrusion of lumbar intervertebral disc in our hospital from January 2016 to March 2017 were selected and divided into the observation group and the control group according to the order of treatment,with 59 cases in each group.The control group was treated with routine nursing,while the observation group was given high quality nursing.The quality of life,nursing satisfaction,pain degree and SAS and SDS scores were compared between the two groups.Results After nursing,the scores of physical ability,social ability,health index in the observation group were higher than those in the control group;the SAS and SDS scores were lower than those in the control group;the degree of pain was lower than that in the control group;the nursing satisfaction was higher than that in the control group,the differences were statistically significant (P<0.05).Conclusion The application value of high quality nursing care in the treatment of lumbar disc herniation in nursing,can improve the quality of life of patients,improve the bad mood,relieve pain,improve patient satisfaction.It is worthy of clinical use. 2017 Vol. 24 (25): 174-176 [Abstract] ( 227 ) HTML (1 KB)  PDF (669 KB)  ( 80 ) 177 Application effect of evidence-based nursing in patients with calculous cholecystitis during perioperative period ZHENG Ai-hua Objective To investigate the application effect of evidence-based nursing in patients with calculous cholecystitis during perioperative period.Methods 120 patients with calculous cholecystitis treated in our hospital from May 2016 to May 2017 were selected and randomly divided into observation group and control group.Observation group was given evidence-based nursing,while control group only received general clinical nursing.The incidence of complications,patients′ psychological status and patients′ and their families′satisfaction degree were compared between the two groups.Results The total incidence of complications of observation group was lower than that of control group (P<0.05).The post-nursing SAS and SDS score of observation group were significantly lower than those of control group (P<0.05).The patients′ satisfaction degree with medical staff of observation group pre-,intra-and post-operation were higher than those of control group (P<0.05).Conclusion Evidence-based nursing applied in patients with calculous cholecystitis during the perioperative period can effectively reduce the incidence of complications,make the patients maintain a good state of mind and improve their satisfaction,which is worthy of clinical promotion. 2017 Vol. 24 (25): 177-179 [Abstract] ( 200 ) HTML (1 KB)  PDF (708 KB)  ( 119 ) 179 Efficacy of clinical nursing pathway on inguinal hernia patients with laparoscopic total peritoneal hernia repair FAN Yue-xiu, LIAO Qiu-mei, FAN Hui-qin, HU Xian-yan Objective To investigate efficacy of clinical nursing pathway on inguinal hernia patients with laparoscopic total peritoneal hernia repair(TEP),and the influence on serum level of C-reactive protein (CRP).Methods 82 patients with inguinal hernia in our hospital from June 2015 to December 2016 were selected and randomly divided into the control group and the observation group,with 41 cases in each group,all cases were treated with TEP.The control group was given with routine nursing care,while the observation group was given clinical nursing pathway.The postoperative exhaust time,off-bed activity time,length of hospital stays,postoperative recovery time,complication,nursing satisfaction and serum CRP were compared between two groups.Results The postoperative exhaust time,off-bed activity time,length of hospital stays and postoperative recovery time in the observation group were shorter than those in the control group,the incidence of complication was lower than that in the control group,and the differences were statistically significant (P<0.05).Before operation,there were no significant differences in the level of serum CRP between two groups (P>0.05);12,24 h after operation,the level of serum CRP in two groups were all increased,and compared with those before operation,the differences were statistically significant (P<0.01),but those in the observation group was lower than those in the control group,and the differences were statistically significant (P<0.01).Conclusion Clinical nursing pathway can shorten time of postoperative exhaust time,bed time after operation,postoperative hospitalization,postoperative recovery time for inguinal hernia patients after TEP,reduce complications,increase satisfaction,and inhibiting serum level of CRP. 2017 Vol. 24 (25): 179-182 [Abstract] ( 225 ) HTML (1 KB)  PDF (735 KB)  ( 93 ) 183 Effect analysis of high quality nursing intervention on prevention of nosocomial infection in“rooming-in”in obstetrical department HU Hui-ying Objective To explore the efficacy of high quality nursing intervention on prevention of nosocomial infection in “rooming-in”.Methods A total of 71 delivered puerperae from January 2014 to August 2015 in “rooming-in” in our hospital were selected.According to the order of admission and a random number table,all participants were divided into control group (n=35) and observation group (n=36).In the control group,regular nursing was used,while in the observation group,high quality nursing intervention was adopted.The incidence of nosocomial infection and nursing satisfaction were compared between the two groups.Results In the observation group,the incidence of nosocomial infection including upper respiratory tract infection,superficial incision infection,and urinary system infection,etc. was 8.3%,much lower than that in the control group accounting for 34.3% (P<0.05).The nursing satisfaction in the control group was 80.0%,while in the observation group,the satisfaction rate was 97.2%.The nursing satisfaction in the observation group was significantly higher than that in the control group (P<0.05).Conclusion High quality nursing intervention on the prevention of nosocomial infection including upper respiratory tract infection and superficial wound infection,etc.in “rooming-in” in obstetrical department obtains a prominent effect,and is well-recognized by patients,which is worthy of promotion. 2017 Vol. 24 (25): 183-185 [Abstract] ( 203 ) HTML (1 KB)  PDF (716 KB)  ( 99 ) 186 Application effect of perioperative multi-level care in the operation of breast cancer TIAN Hong, ZHANG Chao-hong, PENG Jian-you, LIN Ze-hua, LUO Wei-fang, LI Xuan Objective To investigate the effect of perioperative multi-level care in the treatment of breast cancer. Methods From January 2014 to December 2016 in our hospital 66 patients underwent surgical treatment of breast cancer patients as the research object,randomly divided into control group (n=33),the operation room routine nursing)and observation group (n=33,the perioperative nursing of multi-level).Two groups were compared with surgery,comfort and the degree of satisfaction.Results In the observation group,the postoperative coordination degree was 100%,which was significantly higher than that of the control group (87.9%);The overall comfort of the observation group was [(18.58±1.93) points],which was significantly higher than that of the control group [(13.56±2.37) points];The satisfaction rate of patients in the observation group was 93.9%,which was significantly higher than that of the control group (72.7%),and the differences were statistically significant (P<0.05).Conclusion The perioperative application of multi-level care in breast cancer surgery has good effect,can improve the patient's surgical cooperation,comfort and patient satisfaction. 2017 Vol. 24 (25): 186-188 [Abstract] ( 223 ) HTML (1 KB)  PDF (718 KB)  ( 157 ) 189 Application of system nursing intervention in patients with chronic gastritis and gastric ulcer LIU Yi-lan Objective To explore the effect of system nursing intervention on the curative effect,adverse psychological and quality of life of patients with chronic gastritis complicated with gastric ulcer.Methods 120 patients with chronic gastritis complicated with gastric ulcer in our hospital from March 23th 2015 to March 23th 2016 were selected and randomly divided into the observation group and the control group,with 60 cases in each group.The control group was given routine nursing and the observation group was given system care interventions.The treatment effect,self-management ability,quality of life and anxiety and depression degree were compared between two groups.Results The HP negative rate in the observation group was higher than that in the control group,the adverse event rate was lower than that in the control group,clinical symptoms disappear time was shorter than that in the control group,self-management ability was higher than that in the control group,and the differences were statistically significant (P<0.05).Before nursing,there were no significant differences in the scores of indexes in quality of life and SAS,SDS in two groups (P>0.05);after nursing,the scores of indexes in quality of life in the observation group was higher than that in the control group,the scores of SAS and SDS were lower than those in the control group,and the differences were statistically significant (P<0.05).Conclusion Systematic nursing intervention has significant effect in patients with chronic gastritis complicated with gastric ulcer,which can improve the quality of life of patients,improve anxiety and depression in patients,improve patient compliance,HP negative rate and self-management ability score. 2017 Vol. 24 (25): 189-192 [Abstract] ( 222 ) HTML (1 KB)  PDF (720 KB)  ( 97 ) 192 Application of high quality nursing in patients with gastrointestinal endoscope anesthesia JIANG Xue-qin Objective To explore the application of quality nursing in patients with painless gastrointestinal endoscope anesthesia.Methods A total of 120 patients who underwent painless gastrointestinal anesthesia in our hospital from July 22th 2015 to July 22th 2016 were selected and were randomly divided into the observation group and the control group.The control group was given routine nursing,while the observation group was given high quality nursing.The cooperate,nursing satisfaction,compliance,incidence of adverse reaction and anxiety and depression degeree were compared between two groups.Results The cooperate,nursing satisfaction,compliance in the observation group were higher than those in the control group,the incidence of adverse reaction was lower than that in the control group,and the differences were statistically significant (P<0.05).Before nursing,there were no significant differences among the scores of SAS and SDS in two groups (P>0.05);after nursing,the scores SAS and SDS in the observation group were lower than those in the control group,and the differences were statistically significant (P<0.05).Conclusion It is possible to improve the patients′ cooperation rate,improve the negative emotions,improve the compliance and reduce the incidence of adverse reactions in patients with painless gastrointestinal endoscope anesthesia. 2017 Vol. 24 (25): 192-194 [Abstract] ( 216 ) HTML (1 KB)  PDF (718 KB)  ( 91 ) 195 Analysis on the application method and effect of psychological and behavioral intervention on the nursing of patients with epistaxis OUYANG Mei, WANG Min, LIU Wen, XIAO Yan, XIAO Bing Objective To explore the efficacy of psychological and behavioral intervention on the nursing of patients with epistaxis.Methods 81 patients with epistaxis in our hospital from January 2016 to January 2017 were selected and were randomly divided into the observation group (n=41) and the control group (n=40).The control group was treated by routine nursing,while the observation group was given psychological and behavioral intervention on the basis of the control group.The treatment effect,nursing satisfaction and the degree of anxiety and depression were compared between two groups.Results The total effective rate and nursing satisfaction in the observation group was higher than that in the control group,and the differences were statistically significant (P<0.05).Before nursing,there were no significant differences in the scores of SAS and SDS in two groups (P>0.05);after nursing,the scores SAS and SDS in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).Conclusion The psychological intervention in the nursing care of patients with nasal bleeding effect is outstanding,it can improve the patients′ mental state,by the recognition,which is worthy of clinical application. 2017 Vol. 24 (25): 195-197 [Abstract] ( 189 ) HTML (1 KB)  PDF (707 KB)  ( 93 )

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