无痛内镜下注射止血联合大剂量埃索美拉唑治疗消化性溃疡出血的临床研究

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Abstract Objective To investigate the clinical efficacy of painless endoscopic injection of hemostasis combined with high-dose Esomeprazole in the treatment of peptic ulcer bleeding.Methods 90 case of peptic ulcer bleeding patients in our hospital from March 2015 to February 2017 were selected and randomly divided into group A(30 patients with high-dose Esomeprazole),group B(painless endoscopic injection of hemostatic combined with conventional doses of Esomeprazole,30 patients),group C(painless endoscopic injection of hemostasis combined with high-dose Esomeprazole treatment,30 cases),The three groups of stop bleeding time,length of stay,hospital costs and re-bleeding and surgery were compared.Results The time of stop bleeding,hospitalization and hospital costs were higher in group A than those in group B and group C.The time of stop bleeding,hospitalization and hospital costs in group B were higher than those in group C（P<0.01）.The rate of rebleeding was higher in group A than that in group C,and the rate of operation was higher than that of group B and C(P<0.05).Conclusion Painless Endoscopic injection of hemostatic combined with high doses of esomeprazole in patients with peptic ulcer bleeding treatment can improve the hemostatic effect,reduce the incidence of rebleeding.

Key words： Peptic ulcer Bleeding Painless endoscopy Esomeprazole

Received: 15 June 2017

PACS:

R573.1

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	Articles by authors
	ZHOU Lei
	SU Chu-xia
	LI Chun-nan
	DING Zi-le

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ZHOU Lei,SU Chu-xia,LI Chun-nan, et al. Clinical study of painless endoscopic injection of hemostasis combined with high dose Esomeprazole in the treatment of peptic ulcer bleeding[J]. 中国当代医药, 2017, 24(25): 20-22.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I25/20

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