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Quick Search     Adv Search 2018 Vol. 25, No. 28 Published: 2018-10-08   4 Effect of Arnebia Root Oil on tissue repair and expression of TGF-β1 and Smad3 after anal fistula surgery ZHAO Cheng;WANG Wei-juan Objective To explore the mechanism of Arnebia Root Oil promoting wound healing by studying the expression changes of TGF-β1and Smad3 factors after anal fistula surgery.Methods A total of 90 anal fistula patients admitted to our hospital from March 2017 to March 2018 were enrolled in this study.They were divided into the Arnebia Root Oil group(n=30),Fuzhiqing group(n=30)and Vaseline group(n=30)according to the simple random method.In the Arnebia Root Oil group,Arnebia Root Oil was used,while in the Fuzhiqing group,Fuzhiqing for external application was used,and in the Vaseline group,Vaseline for external application was adopted.Expression of TGF-β1and Smad3 factors among three groups was compared and detected by reverse transcription-polymerase chain reaction(RTPCR)and Western blot.Results RT-PCR and Western blot showed that the content of TGF-β1in the Arnebia Root Oil group increased gradually.On the 21stday after treatment,the content of TGF-β1in the Arnebia Root Oil group was higher than that in the Fuzhiqing and Vaseline groups with statistical significances(P<0.05).On the 21stday after treatment,the content of Smad3 in the Arnebia Root Oil group was lower than that in the Fuzhiqing and Vaseline groups,which differed statistically (P<0.05).Meanwhile,the healing time in the Arnebia Root Oil group was shorter compared with that of the other two groups (P<0.05).Conclusion Arnebia Root Oil can effectively promote wound healing after anal fistula surgery,which may be regulated by TGF-β1up-regulation and Smad3 down-regulation,thus providing a preliminary theoretical basis for Arnebia Root Oil treatment after anal fistula surgery identified as a damp-heat pouring downward pattern. 2018 Vol. 25 (28): 4-08 [Abstract] ( 160 ) HTML (49 KB)  PDF  (0 KB)  ( 137 ) 9 Application effect of Edaravone in the elderly patients with laparoscopic cholecystectomy YIN Zeng-sheng;LI Shu-qin;CUI Hui Objective To investigate the effect of Edaravone on postoperative cognitive function in elderly patients undergoing laparoscopic cholecystectomy.MethodsA total of 80 elderly patients who underwent laparoscopic cholecystectomy from October 2017 to June 2018 in our hospital were selected and they were randomly divided into the Edaravone group and control group,and there were 40 cases in each group.Edaravone group was dripped Edaravone of 0.5 mg/kg via peripheral vein 20 minutes before anesthesia induction(dilute with physiological saline to 100 ml),drop finished in 30 min,the control group was given such as capacity of physiological saline in the same conditions.The serum S-100β protein levels,mini-mental state examination (MMSE)score and the incidence of postoperative cognitive dysfunction(POCD)at different times were compared between the two groups.Results The serum S-100β protein concentrations in the Edaravone group were lower than those in control group at 6,24 hours after operation,and the differences were statistically significant(P<0.05).The MMSE scores of the Edaravone group were higher than those of control group at 6,24 hours after operation,and the differences had statistical significance(P<0.05).The incidence of POCD in the Edaravone group were significantly lower than those in control group at different times,and the differences were statistically significant(P<0.05).Conclusion Edaravone can significantly reduce the incidence of postoperative cognitive dysfunction in elderly patients undergoing laparoscopic cholecystectomy,has a certain protective effect on the postoperative cognitive function. 2018 Vol. 25 (28): 9-12 [Abstract] ( 165 ) HTML (41 KB)  PDF  (0 KB)  ( 133 ) 13 Epidemiological characteristics of 558 cases with obstructive diseases of urinary system and analysis of the risk factors affecting the prognosis of renal functions HE Ping-hong;MA Guo-ying;DA Jing-jing;HU Ying;ZHA Yan Objective To analyze the epidemiological characteristics of urinary obstructive diseases and explore the risk factors affecting the prognosis of renal function.Methods The electronic medical records of 588 patients with urinary tract obstruction who were more than 18 years old and diagnosed by urinary tract B ultrasound or iconography from January to June 2015 in the department of urology and department of nephrology of 5 gradeⅢA hospitals in Guizhou province were retrospectively selected.The distribution features of general situation,obstruction cause,obstruction time,water accumulation degree,preoperative and postoperative white blood cells,serum creatinine and urine routine,preoperative urine routine,blood calcium,blood phosphorus,blood uric acid,blood C reactive protein,serum albumin,blood HCO3-concentration and complications were collected.And the risk factors of postoperative renal function prognosis were analyzed.Results Among 558 cases collected,there were 384 male and 173 female;and 253 cases were farmers(45.35%).The main disease cause of 422 cases was urinary calculi(75.6%).Renal function impairment was observed in 354 patients(63.44%)(eGFR<60 ml/min),of whom 53(9.5%)had end-stage renal disease.303 cases of preoperative eGFR<60 ml/min patients were treated by surgery,of whom the renal function of 242 cases (eGFR>60 ml/min,80%)was recovered and the renal function of 61 cases(20%)was not recovered(GFR<60 ml/min)at postoperative 3 months.Common complications included renal impairment in 354 cases(63.44%)and cystitis in 252 cas-es(45.2%).Logistic regression analysis of 21 factors was carried out in patients(eGFR<60 ml/min)who underwent preoperative surgery.The results showed that male,age,renal atrophy and preoperative eGFR decrease were risk factors affecting renal function recovery (P<0.05).Conclusion The incidence rate of urinary tract obstructive diseases is high in male patients and peasants.The most common disease is urinary calculi.There is a great chance of renal function damage.Male,age,renal atrophy and preoperative eGFR decrease are risk factors affecting renal function recovery. 2018 Vol. 25 (28): 13-16 [Abstract] ( 164 ) HTML (42 KB)  PDF  (0 KB)  ( 27 ) 17 Effect of using 3D printing model in endoscopic endonasal surgical practice YI Xue-han;LAI Hai-chun;LIU Jian-zhi;LIN Shu-chun;LI Chen;CHEN Xiao-qiang;WANG De-sheng Objective To explore the effect of using 3D printing model in endoscopic endonasal surgical practice.Methods The surgical training model was made using 3D printing technology.In January 2018,12 postgraduates and low-grade resident doctors with no experiences of endoscopic endonasal surgery were recruited to participate in the surgical training used the 3D printing model as tools.Drilling,curetting,biting and aspirating under endoscope were practiced repeatedly used the eggs fixed on the 3D printing model as objects.The training results and the subjective feelings after training for each practitioner were recorded.Results As the number of training was increased,the speed and quality of the endoscopic operation for these practitioners were increased gradually.Compared with the first training,the results of the last training(the fifth time)of practitioners,including the time spent in drilling the eggshell([3.93±0.77])min vs.[2.87±0.44]min)(P<0.001),the probability of shell membrane rupture during drilling the eggshell(11/12 vs.4/12)(P=0.009),the probability of shell membrane rupture during curetting and biting the eggshell(12/12 vs.6/12)(P=0.014),the probability of yolk membrane rupture during aspirating the albumen(7/12 vs.1/12)(P=0.027),and the surgical practice score([2.17±0.72]points vs.[4.75±0.87]points)(P<0.001),were improved significantly.Moreover,all of the participants subjectively stated that they could obtain benefits from the practice and willing to train with 3D printed models.Conclusion The endoscopic endonasal surgical practice using 3D printed model as tools can effectively improve the endoscopic surgical operation skills of practitioners and may contribute to stimulate the enthusiasm of practitioners. 2018 Vol. 25 (28): 17-20 [Abstract] ( 134 ) HTML (40 KB)  PDF  (0 KB)  ( 22 ) 21 Influence of non-invasive ventilation combined with blood purification on inflammatory factors and oxidative stress in patients with acute respiratory distress syndrome PU Yi-hua;LI Jin-hua;MENG Ji-shen;ZHANG Xing-yu;JIN Ming-gen Objective To study the influence of non-invasive ventilation combined with blood purification on inflammatory factors and oxidative stress in patients with acute respiratory distress syndrome.Methods All of 78 patients with acute respiratory distress syndrome admitted into our hospital from January 2015 to May 2017 were selected as the study subjects.They were divided into the control group(n=39)and observation group(n=39)according to the random number table method.The control group was treated with non-invasive ventilation,and the observation group was treated with non-invasive ventilation combined with blood purification.The levels of inflammatory factors and oxidative stress reaction indexes were compared between the two groups.Results After treatment,the levels of TNF-α,IL-1β and IL-6 inflammatory factors in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The CRP level in the observation group was higher than that in the control group,and the degree of reduction of SOD and GSH-Px in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The increase of MDA in the observation group was lower than that in the control group (P<0.05).Conclusion non-invasive ventilation combined with blood purification treatment for patients with acute respiratory distress syndrome can help to stabilize inflammatory factors and oxidative stress,ensure clinical efficacy,and promote the early recovery of patients,which is worthy of popularization and application. 2018 Vol. 25 (28): 21-24 [Abstract] ( 154 ) HTML (41 KB)  PDF  (0 KB)  ( 25 ) 25 Efficacy of non-left main bifurcation lesions of coronary artery treated by T-stenting with small protrusion TU Jie-hong;LI Shun-hui;YAN You-liang;CHEN Hui;TONG Yi-fan;LI Jun-hua Objective To investigate the clinical effect of T-stenting with small protrusion(TAP)technique for non-left main bifurcation lesions of coronary artery,and to compare it with the DK-Crush technique.Methods Eighty patients with non-left main bifurcation lesions of coronary artery admitted to the first department of cardiology,the third affiliated hospital of Nanchang university from July 2014 to March 2017 were enrolled.They were equally divided into TAP group and DK-Crush group in random.The success rate of immediate percutaneous coronary intervention (PCI),the condition of bifurcation,the use of instruments(including number of stents and balloons),X-ray exposure time,contrast agent usage,incidence of stent thrombosis during hospitalization,and incidence of major adverse cardiac events(MACE,including sudden cardiac death,myocardial infarction,stent thrombosis,target vessel revascularization)after 12 months of follow-up were compared in the two groups.Results There was no significant difference in the success rate of immediate PCI between the two groups (P>0.05).In the TAP group,the number of balloons used and angiographic doses were both less compared with those in the DK-Crush group with statistical significance(P<0.05).The X-ray exposure time of the TAP group was shorter than that of the DK-Crush group with a significant difference(P<0.05).No significant difference was displayed in the incidence of MACE after 12 months of follow-up(P>0.05).There was no significant difference in the incidence of stent thrombosis during hospitalization and the incidence of intramural restenosis within 6 to 12 months between the two groups(P>0.05).Conclusion The short-term and long-term clinical efficacy of TAP in the treatment of non-left main bifurcation lesions of coronary artery is comparable to that of DKCrush,but it significantly shortens the exposure time,and reduces the amount of contrast agent,the use of surgical instruments,and medical expenses. 2018 Vol. 25 (28): 25-28 [Abstract] ( 154 ) HTML (44 KB)  PDF  (0 KB)  ( 25 ) 29 Progress in clinical research on endometrial polyps JIANG Ling-li;WU Fang-yue Endometrial polyp occurs on the surface of the endometrium,and is a new organism with pedicles or without pedicle protruding from the uterine cavity due to excessive proliferation of the endometrium.The incidence among women is high and can increase the rate of infertility.Most endometrial polyps are benign,and few of them will progress to endometrial cancer.Hysteroscopy is the main method of diagnosis and treatment,and recurrence after resection is a difficult issue.This article reviews the progress of hysteroscopy in the diagnosis,treatment,postoperative recurrence and prevention of endometrial polyps. 2018 Vol. 25 (28): 29-31转35 [Abstract] ( 162 ) HTML (45 KB)  PDF  (0 KB)  ( 25 ) 32 Effects of different postures on tidal volume changes in patients with chronic pulmonary heart disease under mechanical ventilation ZHONG Dong-ying;LIANG Qian;HUANG Cai-yun Objective To explore the effect of different body positions on the change of moisture content under mechanical ventilation in patients with chronic pulmonary heart disease,and to provide a basis for the formulation of mechanical ventilation for such patients.Methods 50 cases of chronic pulmonary heart disease in our hospital from June 2013 to June 2015 were selected as the case group.At the same time,50 patients in the department of digestive medicine,department of orthopedics and ophthalmology at the same time were selected as the healthy control group.Each group was randomly divided into supine group and lateral decubitus group.The tidal volume,lung function,blood gas analysis and hospitalization were analyzed and compared under different body positions.Results In patients with chronic pulmonary heart disease,the volume of tidal gas under mechanical ventilation was lesser than that of the control group,while the peak volume ratio and the peak time ratio were lesser than those of the normal people.In addition,the tidal volume of the lateral position was lesser than that in the supine position,but the ratio of peak volume to peak time was longer than that in the supine position.The differences were statistically significant(P<0.05）.The results of blood gas analysis showed that the blood gas analysis index of patients using supine position for mechanical ventilation was better than that in lateral decubitus group,and the proportion of lung infection in supine group was lower than that in lateral supine group,the differences were statistically significant(P<0.05）.There was no significant difference in the average length of stay between the two groups(P＞0.05）.Conclusion when the patients adopt the lateral position,the decrease of lung compliance caused by the decrease of the muscle activity of the respiratory tract leads to the further decrease of its tidal volume,and the peak volume ratio and the peak time ratio will increase because of the improvement of the airway obstruction and the decline of the tidal volume.On the supine,the increase of tidal volume due to the increase of lung compliance has successfully improved the therapeutic effect of mechanical ventilation and improved the internal environment disturbance of patients. 2018 Vol. 25 (28): 32-35 [Abstract] ( 171 ) HTML (36 KB)  PDF  (0 KB)  ( 31 ) 36 Effect of laparoscopic and open cholecystectomy on the biochemical indicators in patients with gallstone ZENG Xian-min;ZHOU Xiao-long;ZENG Dong-mei Objective To study the effect of laparoscopic and open cholecystectomy on the biochemical indexes of patients with gallstones.Methods From July 2016 to July 2017,90 patients with gallstones admitted to People′s Hospital of Jishui County in Jiangxi Province were studied.After obtaining the patients′consent,the patients were randomly divided into control group and observation group,45 cases in each group.The control group was given open surgery.The observation group was given for laparoscopic cholecystectomy.The blood parameters(including WBC and neutrophils),liver function indexes(including GGT,ALT,TBIL,AST,and CRP)and immunoglobulins(including IgG,IgM,and IgA)of the two groups were detected and compared.Two groups of postoperative fatigue scores were compared.Results The indexes of blood,liver function and immunoglobulin in the observation group were significantly lower than those in the control group,postoperative fatigue score index was significantly lower than that in the control group,there were statistically significant differences between the two groups(P<0.05）.Conclusion Laparoscopic cholecystectomy for patients with gallbladder stones has a smaller impact on the patients′biochemical parameters.The patients′degree of postoperative fatigue is low and it is an ideal surgical method.It is worthy of popularization and application. 2018 Vol. 25 (28): 36-38 [Abstract] ( 153 ) HTML (37 KB)  PDF  (0 KB)  ( 32 ) 39 Changes of GFAP protein in cerebrospinal fluid after severe craniocerebral injury and its correlation with intracranial pressure TU Yao-ran;NIU Fan;HONG De-quan Objective To investigate the changes of serum glial fibrillary acidic protein (GFAP)in cerebrospinal fluid(CSF)after severe craniocerebral injury and its correlation with intracranial pressure,so as to provide a basis for improving the diagnosis and treatment of severe craniocerebral injury.Methods A total of 42 cases of severe craniocerebral injury treated in our hospital from October 2016 to August 2017 were selected as the experimental group,and 42 cases of healthy physical examination or volunteers were selected as the control group.The cerebrospinal fluid samples were extracted from 6,12,24,48 and 72 h after injury,and the level of GFAP protein was detected,and the changes of intracranial pressure were monitored continuously,and the level of GFAP protein and intracranial pressure were compared with that of the intracranial pressure.At the same time,the correlation between the change of GFAP protein and the intracranial pressure at each time point after injury in the study group were analyzed.Results①The level of GFAP protein in cerebrospinal fluid in the experimental group was significantly higher than that of the control group(P<0.05）,and the 24 h reached the peak value in the experimental group after brain injury and decreased with the time.②The intracranial pressure increased immediately after injury in the experimental group,and the intracranial pressure at all time points was significantly higher than that of the control group(P<0.05）.The peak of intracranial pressure in the experimental group occurred at 48 h after injury,and the intracranial pressure remained at a high level after 48 h.③The intracranial pressure and cerebrospinal fluid GFAP protein in the experimental group showed an upward trend and a positive correlation (r=6.483,P<0.05）.ConclusionAfter severe craniocerebral injury,GFAP protein and intracranial pressure in cerebrospinal fluid are elevated,and their changes in early stage are consistent.The detection of GFAP protein and intracranial pressure in cerebrospinal fluid can be used for clinical diagnosis,to grasp the evolution of the disease and to provide reference for the treatment. 2018 Vol. 25 (28): 39-41 [Abstract] ( 185 ) HTML (34 KB)  PDF  (0 KB)  ( 22 ) 42 Ultrasound guided abdominal abscess puncture and surgical incision for drainage in the application of patients with abdominal abscess ZHOU Chao-yang;HU Xue-fei Objective To compare the effect of ultrasound-guided abdominal abscess puncture and surgical incision for drainage in patients with abdominal abscess.Methods A total of 70 patients with abdominal abscess from October 2010 to January 2018 in Dapeng Xinqu Maternal and Child Health Care Hospital were selected.They were equally divided into surgical group and puncture group by a random number table methed.In the surgical group,surgical incision for drainage was used,while in the puncture group,ultrasound-guided abdominal abscess puncture was adopted.The clinical efficacy,perioperative indicators,and complications were compared between the two groups.Results After corresponding treatments in the two groups,the cure and improvement rate was 97.14%,which was higher than that in the surgical group accounting for 68.57%with a significant difference between the two groups(χ2=10.057,P<0.01）.In the puncture group,hospital stay was shorter than that of the surgical group,and the pain level was milder than that of the surgical group(P<0.05）.The total incidence of postoperative complications in the puncture group was 5.71%(2/35),lower than that in the surgical group accounting for 28.57%(10/35)with statistical significance(P<0.05）.Conclusion Ultrasoundguided abdominal abscess puncture can significantly improve efficacy,shorten hospital stay,relieve pain,and reduce the risk of complications,and has a higher clinical application value compared with surgical incision for drainage. 2018 Vol. 25 (28): 42-44 [Abstract] ( 166 ) HTML (36 KB)  PDF  (0 KB)  ( 20 ) 45 Effect of urinary microprotein/creatinine ratio to cardiac function and glycometabolism in patients with coronary heart disease complicated type 2 diabetes mellitus ZHANG Ruo-lan;ZHANG Li-yan Objective To investigate effect of urinary microprotein/creatinine ratio (A/C)on cardiac function and glycometabolism in patients with coronary heart disease complicated type 2 diabetes mellitus(T2DM).Methods A total of 826 patients with coronary heart disease complicated T2DM form January 2015 to December 2017 were selected as subjects and were divided into A/C abnormal group(n=472)and A/C normal group(n=354)according to the A/C ratio.The differences of cardiac function parameters,blood glucose,insulin resistance index(IR)and blood lipid levels were contrasted between A/C abnormal group and A/C normal group,and correlation between A/C ratio and cardiac function parameters and glucolipid metabolism was analyzed.Results The left ventricular ejection fraction (EF%)in the A/C abnormal group was lower than that in the A/C normal group,the difference was statistically significant(P<0.05).Left ventricular end systolic diameter(LVESD)and left ventricular end diastolic diameter(LVEDD)in the A/C abnormal group were higher than those in the A/C normal group,the differences were statistically significant (P<0.05).The fasting plasma glucose(FPG),2-hour postprandial blood glucose(2 h PG),IR,triglyceride(TG),low density lipoprotein cholesterol(LDL-C),small dense low-density lipoprotein cholesterol(sd LDL-C)in the A/C abnormal group were higher than those in the A/C normal group,the differences were statistically significant(P<0.05).And level of total cholesterol(TC)in the A/C abnormal group was lower than that in the A/C normal group,the differences were statistically significant(P<0.05).Conclusion A/C ratio could predict level of glucose,lipid metabolism and cardiac function in patients with coronary heart disease complicated T2DM. 2018 Vol. 25 (28): 45-47转51 [Abstract] ( 176 ) HTML (37 KB)  PDF  (0 KB)  ( 28 ) 48 Effect Contrast of Levosimendan and Dobutamine Hydrochloride on acute heart failure and its effect on the level of BNP TAN Wei-hua;QING Guo-zhong;LU Wei;PENG Zheng-liang Objective To discuss the effect of Levosimendan and Dobutamine Hydrochloride on the treatment of acute heart failure and its effect on the level of BNP.Methods A total of 100 patients with acute heart failure who were admitted to our hospital from February 2017 to March 2018 were selected as study objects and divided into two groups according to the random number table method.And 50 patients in the control group were treated with Dobutamine Hydrochloride,and 50 patients in the observation group were treated with Leosimendan.Routine examination and standard medication were administered to both groups.After 7 days of treatment,the clinical effects of the two groups were compared.The improvement of the left ventricular end-systolic volume (LVESV),left ventricular end-diastolic volume(LVEDV),left ventricular ejection fraction (LVEF)and stroke volume (SV)of the two groups were compared.The changes of brain natriuretic peptide(BNP),inflammatory molecular indicators[interleukin-6(IL-6),tumor necrosis factor-α (TNF-α),hypersensitive c-reactive protein(hs-CRP)]in the two groups were compared.Adverse reactions were compared between the two groups.Results After the treatment,the overall effective rate of clinical treatment in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).After treatment,the LVESV and LVEDV in the two groups were lower than those before treatment,the LVEF was higher than that before treatment,and SV in the observation group was higher than that before treatment,the differences were statistically significant(P<0.05).After treatment,the LVESV in the observation group was lower than the control group,and LVEF and SV were higher than those in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of BNP,IL-6,TNF-α,and hs-CRP in the two groups were all lower than those before treatment,the differences were statistically significant(P<0.05).And the levels of BNP,IL-6,TNF-α,and hs-CRP in the observation group were all lower than those in the control group,the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The clinical effect of Leosimendan on the treatment of acute heart failure is better than that of Dobutamine Hydrochloride.And Leosimendan can reduce the level of BNP and be reliability. 2018 Vol. 25 (28): 48-51 [Abstract] ( 164 ) HTML (38 KB)  PDF  (0 KB)  ( 29 ) 52 Clinical effect of Bivalirudin in the treatment of acute myocardial infarction with cardiovascular intervention FAN Ai-de Objective To investigate the clinical effect of Bivalirudin in the treatment of acute myocardial infarction with cardiovascular intervention.Methods A total of 100 patients with acute myocardial infarction admitted to our hospital from August 2016 to August 2017 were selected as the study subjects.The patients were divided into control group and experimental group.There were 50 patients in each group.Patients received common heparin for anticoagulant therapy,meanwhile patients in the experimental group took bivalirudin for anticoagulant therapy.The surgical data,TIMI flow improvement,and postoperative MACE bleeding were compared between the two groups.Results There was no significant difference in the surgical data between the two groups(P>0.05).The TIMI blood flow improvement in the experimental group was better than that in the control group,the difference was statistically significant(P<0.05).The incidence of MACE and bleeding within 30 days after surgery were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The treatment of patients with acute myocardial infarction who received Bivalirudin combined with cardiovascular intervention has achieved significant therapeutic effect,with high safety,and it is worthy of being more widely used in clinical practice. 2018 Vol. 25 (28): 52-54 [Abstract] ( 143 ) HTML (35 KB)  PDF  (0 KB)  ( 37 ) 55 Effect of Sodium Phosphocreatine in adjuvant treatment of chronic heart failure and its impact on cardiac function,hypersensitive C reactive protein and N-terminal B brain natriuretic peptide LI Shu-qing Objective To explore the clinical effect of application of Sodium Phosphocreatine in the adjuvant treatment of chronic heart failure(CHF).MethodsAltogether 98 CHF patients who were admitted to our hospital from June 2014 to June 2017 were selected as subjects and divided into two groups according to the random number table method.The control group(49 cases)was treated with routine symptomatic therapies,such as heart strengthening,diuresis promotion and vasodilation;while,the observation group (49 cases)was given intravenous drip of Sodium Phosphocreatine on this basis of control group.The clinical efficacy and changes of pre-and post-treatment cardiac function index(including left ventricular ejection fraction[LVEF],left ventricular end systolic/diastolic diameter[LVESD and LVEDD]),serological index(including hypersensitive C reactive protein[hs-CRP]and N terminal B brain natriuretic peptide[NT-proBNP])were compared between two groups.Results The post-treatment total effective rate of the observation group was 89.80%,which was significantly higher than that of the control group of 73.47%,the difference was statistically significant(P<0.05).The post-treatment LVEF values of the two groups were significantly higher than those before treatment,the post-treatment LVESD and LVEDD values of the two groups were significantly lower than those before treatment,the differences were statistically significant(P<0.05).And the post-treatment LVEF values of the observation group was significantly higher than control group,the post-treatment LVESD and LVEDD values of the observation group were significantly lower than control group,the differences were statistically significant(P<0.05).The post-treatment serum hs-CRP and NT-proBNP of the two groups were significantly lower than those before treatment,with statistically significant differences(P<0.01),and the post-treatment serum hs-CRP and NT-proBNP of observation group were lower than those of control group,with statistically significant differences(P<0.01).Conclusion Application of sodium phosphocreatine in treatment of CHF can relieve patients′symptoms,reduce the myocardium injury and improve the heart function,which is worthy of clinical application. 2018 Vol. 25 (28): 55-57转65 [Abstract] ( 164 ) HTML (38 KB)  PDF  (0 KB)  ( 24 ) 58 Effect of acupuncture combined with rehabilitation on quality of life improment of cerebral infarction patients XIANG Jun;ZHANG Yan-ping;YANG Mao-sheng;HUANG Ping-yan;XIANG Wei;ZHANG Mei;WANG Peng;YANG Xiao-yan Objective To investigate the effect of acupuncture combined with rehabilitation on the efficacy of cerebral infarction.Methods A total of 180 patients with cerebral infarction admitted to our hospital from February 2016 to August 2017 were selected as study subjects and divided into treatment group(60 cases),positive control group(60 cases)and negative control group (60 cases)according to random number table method.The treatment group was treated with acupuncture combined with rehabilitation on the basis of routine treatment,the positive control group was treated with rehabilitation on the basis of conventional treatment,and the negative control group was treated with conventional treatment.The clinical efficiency,NIHSS score,quality of life,and cystatin C(Cys-C),C-reactive protein(CRP),homocysteine (Hcy)levels were compared of the three groups.Results The total effective rate of the treatment group was 98.33%,which was higher than that of the negative control group(71.67%)and the positive control group(75.00%),the difference was statistically significant(P<0.05）.After treatment,the neurological deficit scores in the treatment group were lower than those before treatment(P<0.05）.The neurological deficit scores in the treatment group were lower than those in the yin and positive control groups.The difference was statistically significant(P<0.05）.After treatment,the MBI score in the treatment group was higher than that before treatment(P<0.05）.The MBI score in the treatment group was higher than that in the negative and positive control groups.The difference was statistically significant(P<0.05）.The cystatin C,C-reactive protein and homocysteine in the treatment group were lower than those in the negative and positive control groups,and the differences were statistically significant(P<0.05）.Conclusion Acupuncture combined with rehabilitation has higher clinical value in patients with cerebral infarction and can improve the quality of life on the basis of improving neurological function.It is worth applying and popularizing. 2018 Vol. 25 (28): 58-61 [Abstract] ( 161 ) HTML (39 KB)  PDF  (0 KB)  ( 26 ) 62 Clinical relationship between the etiological type and lesion site of acute cerebral apoplexy and plasma homocysteine level FANG Ming Objective To explore the clinical relationship between the etiological type and lesion site of acute cerebral apoplexy and plasma homocysteine (Hcy)level,and to analyze the influence of abnormal elevated plasma Hcy level on the factors risk of acute cerebral apoplexy.Methods A total of 268 patients with acute cerebral apoplexy admitted to our hospital from June 2016 to August 2017 were selected as the observation group,among them,there were 98 cases of large atherosclerotic type,103 cases of small atherosclerotic type,41 cases of cardiogenic embolic type,17 cases of other clear etiological type,9 cases of other undefined etiological type.There were 126 cases of intracranial lesions,83 cases of extracranial lesions and 59 cases of intracranial and extracranial lesions.The level of plasma Hcy in the patients with acute cerebral apoplexy of different etiological types and lesion site were compared,and the influence of abnormal increase of plasma Hcy level on the risk factors of acute cerebral apoplexy were analyzed.Results The Hcy level of the observation group was(19.37±7.01)μmol/L,which was higher than that of the control group([13.25±2.31]μmol/L),the difference was statistically significant(P<0.05).Logistic regression analysis showed that the abnormal increase of plasma Hcy level(>15 μmol/L)was an independent risk factor for acute stroke (β=0.216,SE=0.064,Wald χ2=10.038，P=0.011,OR=1.241,95%CI:1.112-1.429).There was significant difference in plasma Hcy level between acute cerebral apoplexy patients with different etiological factors(P<0.05).The levels of plasma Hcy in the large atherosclerotic type were the highest,and the plasma Hcy level of the cardiogenic embolic type was the second,followed by the cerebral apoplexy of small atherosclerotic type,the cerebral apoplexy with definite cause,and the cerebral apoplexy patients with unclear cause,the differences were statistically significant among all types(P<0.05).There was significant difference in plasma Hcy level between cerebral apoplexy patients with different lesions site (P<0.05).Among them,the plasma Hcy level was the highest in intracranial and extracranial lesions,the plasma Hcy level in intracranial lesions was the second,and the plasma Hcy level in extracranial lesions was the lowest,the differences were statistically significant among all the lesion site (P<0.05).Conclusion There is a significant difference in the level of plasma Hcy in patients with acute cerebral apoplexy with different etiological type and different lesion sites,and the abnormal increase of plasma Hcy is an independent risk factor for acute cerebral apoplexy. 2018 Vol. 25 (28): 62-65 [Abstract] ( 136 ) HTML (39 KB)  PDF  (0 KB)  ( 34 ) 66 Application effect of Statin intensive treatment regimen in the patients with acute cerebral infarction HUANG Wei-dong;LI Liang;LIANG Shi-pan;ZHAO Qin-lian Objective To investigate the application effect of Statin intensive treatment regimen in the patients with acute cerebral infarction.Methods A total of 120 patients with acute cerebral infarction who were treated in the department of neurology in our hospital from January 2016 to February 2018 were selected as subjects and were divided into two groups according to the number grouping method.All patients were given conventional medication.On this basis,the control group was given Atorvastatin Calcium of 20 mg/d for treatment.The observation group was given Atorvastatin Calcium of 40 mg/d for treatment.The clinical efficacy,changes in neurological function before and after treatment,changes in blood lipids and C-reactive protein (CRP)levels,and safety were compared between the two groups.Results The total effective rate in the observation group was 91.67%,which was significantly higher than that of 76.67%in the control group,the difference was statistically significant(P<0.05).The National Institutes of Health Stroke Scale(NIHSS)and the modified Rankin Scale score after treatment in the observation group were significantly lower than in the control group,the differences were statistically significant(P<0.05).Activities of daily living(ADL)score in the observation group was significantly higher than that in the control group,and the differences were statistically significant(P<0.05).The total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C)and CRP in the observation group after treatment were significantly lower than those in the control group,high-density lipoprotein cholesterol(HDL-C)in the observation group was significantly higher than those in the control group,the differences were statistically significant(P<0.05).There were no significant differences in incidence of adverse drug reactions,such as digestive discomfort,insomnia,and transient calf muscle pain,which in the observation group compared with the control group (P>0.05).Conclusion The statin intensive treatment regimen has a significant effect in patients with acute cerebral infarction,which can reduce the mortality rate and disability rate and improve the quality of life.At the same time,it does not significantly increase the adverse reactions of statins,and has a positive clinical significance. 2018 Vol. 25 (28): 66-69 [Abstract] ( 170 ) HTML (41 KB)  PDF  (0 KB)  ( 20 ) 70 Efficacy of Quetiapine combined with Paroxetine in the treatment of bipolar disorder GUAN Kun-lian Objective To explore the effect and experience of Quetiapine combined with Paroxetine in the treatment of bipolar disorder （BP）.Methods A total of 60 patients with BP treated in our hospital from January 2016 to October 2017 were selected as the subjects.According to the treatment time of the patients，they were divided into the control group and study group,30 cases in each group.The control group was treated with Paroxetine,and the study group was combined with Quetiapine.Paroxetine therapy.Before treatment,treament with 14 d,28 d,42 d,and 56 d of Montgomerie depression scale(MARDS),Baker-Lavanmania （BRMS） scale,treatment effect and adverse reaction between the two groups were compared.Results There was no significant difference between the two groups before treatment,14 d,28 d 42 d,and 56 d treatment of MARDS scale,BRMS scale,and treatment effect(P＞0.05）.The total incidence of adverse reactions in the study group was lower than that of the control group,and the difference was statistically significant(P<0.05）.Conclusion The effect of Quetiapine combined with Paroxetine in the treatment of BP is satisfactory.It can obviously improve the quality of life of the patients,and the incidence of adverse reactions in the treatment process is low,and the safety of the drug is high. 2018 Vol. 25 (28): 70-72 [Abstract] ( 142 ) HTML (35 KB)  PDF  (0 KB)  ( 19 ) 73 Clinical effect of drilling and drainage for chronic subdural hematoma CAI Ye-sheng;LU Si-fang;XIE Zhao-tai Objective To investigate the efficacy and safety of drilling and drainage in the treatment of chronic subdural hematoma.Methods A total of 80 patients with chronic subdural hematoma in our hospital from February 2017 to February 2018 were selected and divided into control group (40 cases)and experimental group (40 cases)according to random number table method.The control group was used small bone window craniotomy and the experimental group was used drilling drainage.After treatment of 7 d,the NIHSS and GCS scores of the two groups before and after treatment were compared,and the operative time,hematoma clearance rate and incidence of complications were observed in the two groups.Results There was no significant difference in GCS and NIHSS scores between the two groups before and after treatment(P＞0.05）.After treatment,GCS and NIHSS scores were significantly lower than those before treatment(P<0.05）,and the operation time of the experimental group was significantly shorter than that of the control group(P<0.05）;the postoperative hematoma clearance rate in the experimental group was higher than that of the control group(P<0.05）,and the total incidence of complications in the experimental group was significantly lower than that of the control group,the differences were statistically significant(P<0.05）.Conclusion The effect of drilling and drainage in the treatment of chronic subdural hematoma is better.It can obviously improve the score of GCS and NIHSS,shorten the operation time,improve the clearance rate of hematoma,and reduce the incidence of complications.It is worth popularizing. 2018 Vol. 25 (28): 73-75 [Abstract] ( 158 ) HTML (33 KB)  PDF  (0 KB)  ( 24 ) 76 Effect analysis of surgical treatment of acute subdural hematoma accompanied with cerebral edema JIANG Xi-rang;LYU Wen;SHAN Ai-jun Objective To explore the surgical treatment and clinical effect of acute subdural hematoma(ASDH)accompanied with cerebral edema so as to provide evidence for improving the patients′prognosis.Methods Altogether 86 cases of ASDH accompanied with cerebral edema who were treated in Department of Neurosurgery of our hospital from January 2014 to February 2017 and qualified for case selection criteria were selected as subjects and divided into group A (standard large trauma craniotomy)and group B (conventional craniotomy)according to the random number table method,43 cases in each group.The postoperative follow-up was carried out to observe the complications and the prognostic score system(GOS)was used to evaluate the outcome of treatment in the two groups.Results Only 1 case of acute encephalocele occurred in group A,the incidence of postoperative complications of group A was 2.33%,and the incidence of complications of group B was 13.95%.Two groups had statistically significant difference in the incidence of complications(P<0.05).The treatment outcome of group A was superior to that of group B,the difference was statistically significant(P<0.05).Conclusion The early implementation of standard large trauma craniotomy for ASDH patients accompanied with cerebral edema can effectively improve the quality of the prognosis and reduce the incidence of complications,which is worthy of clinical application 2018 Vol. 25 (28): 76-78 [Abstract] ( 153 ) HTML (35 KB)  PDF  (0 KB)  ( 23 ) 79 Effect comparison of hematoma removal and conventional craniotomy for intracerebral hemorrhage in hypertensive basal ganglia ZHAN Hao-qiang;LI Shao-peng;CHAI Hui-hui Objective To study the effect of microscopic hematoma removal and conventional craniotomy for the treatment of hypertension basal ganglia cerebral hemorrhage.Methods A total of 40 patients with basal ganglia cerebral hemorrhage who were treated in our hospital between January 1,2016 and December 31,2017 were selected as subjects.The patients were divided into 2 groups by odd-even grouping.Each group consisted of 20 patients.The patients in the control group received routine craniotomy.The patients in the experimental group underwent microsurgical hematoma removal.The surgical indexes,the incidence of complications,and the ability of daily living after treatment were compared between the two groups.Results The average surgical time and postoperative hospital stay in the experimental group were shorter than those in the control group,the intraoperative blood loss in the experimental group was less than that in the control group,the differences were statistically significant(P<0.05).The incidence of the disease was 10.00%(2/20),which was lower than the incidence of the control group(40.00%),and the difference was statistically significant(P<0.05).The daily living ability of the experimental group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion The treatment of hypertensive basal ganglia cerebral hemorrhage by microscopic hematoma removal has less trauma to the patient and can reduce the risk of complications.It is worthy of popularization and application. 2018 Vol. 25 (28): 79-81 [Abstract] ( 138 ) HTML (35 KB)  PDF  (0 KB)  ( 31 ) 82 Expression of miR-155 in renal cell carcinoma and its clinical significance LIU Tai-rong;CHEN Hua;SONG Le-ming;YAO Lei;LIU Sheng-feng Objective To investigate the expression and clinical significance of miR-155 in renal cell carcinoma.Methods Real-time quantitative analysis(RT-PCR)was used to detect the expression of miR-155 in 21 renal cell carcinoma tissues and matched normal renal tissues.The relationship between its expression and clinicopathological parameters of renal cell carcinoma was analyzed.Results The expression of miR-155 in renal cell carcinoma was(12.63±6.22),which was significantly higher than that in adjacent normal renal tissues,(2.71±1.38)(P<0.01）.The expression of miR-155 in renal cell carcinoma was not related with the clinical stage,degree of differentiation,gender,age,or tumor diameter(P＞0.05）.Conclusion The expression of miR-155 in cancer tissues in patients with renal cell carcinoma is significantly higher than that in adjacent normal tissues,but without correlation of the pathological grade or clinical differentiation of renal cell carcinoma. 2018 Vol. 25 (28): 82-84 [Abstract] ( 156 ) HTML (36 KB)  PDF  (0 KB)  ( 139 ) 85 Effect comparison of pneumatic lithotripsy and holmium laser lithotripsy in ureteral calculi CAI Jin-Dong Objective To compare the application effect of pneumatic lithotripsy and holmium laser lithotripsy in ureteral calculi.Methods A total of 90 ureteral calculi patients treated in our hospital from September 2016 to September 2017 were selected and divided into observation group (n=45)and control group (n=45)according to random number table method.The pneumatic lithotripsy was performed in the control group;the holmium laser lithotripsy was performed in the observation group.The operation conditions,residual urine volume (Ur),MFR (maximum flow rate)and adverse event rate for two groups were compared.Results The operation time,hospitalization time in the observation group were shorter than that in the control group,blood loss was reduced than that in the control group,with significant difference among groups (t=6.665,12.285,10.873,P<0.05).After treatment,the Ur in the observation group was smaller than that in the control group (t=6.990,P<0.05）;but the MFR in the observation group was significantly higher than that in the control group(t=12.491,P<0.05）;the total incidence of adverse reactions rate in the observation group (2.22%)was significantly lower than that in the control group (13.33%)(χ2=8.607,P<0.05）.Conclusion The holmium laser lithotripsy can remarkably improve the Ur and MFR,reduce the blood loss and adverse event rate,and shorten the hospitalization time.It is worthy of application and promotion. 2018 Vol. 25 (28): 85-87 [Abstract] ( 136 ) HTML (33 KB)  PDF  (0 KB)  ( 20 ) 88 Comparison of percutaneous nephrolithotomy and open surgery for renal calculi LUO Ling-jian Objective To investigate the effect of percutaneous nephrolithotomy and open surgery in the treatment of renal calculi.Methods A total of 100 cases of renal calculi treated in our hospital from January 2014 to January 2017 were selected as the research subjects.According to the different surgical methods,the patients were divided into the observation group (50 cases)and the control group (50 cases),the observation group was treated with percutaneous nephrolithotomy,and the control group was treated with open operation.The incidence of complications,hospitalization time,bleeding volume,operative time,postoperative exhaust time,stone clearance rate and total effective rate were compared between the two groups.Results The total incidence of complications in the observation group was 8.00%,which was lower than that of the control group (20.00%)(P<0.05）.The hospitalization time ([10.21+2.01]d),hemorrhage([70.25±5.01]ml),operation time([70.21±1.45]min)and postoperative exhaust time([28.15±4.01]h)in the observation group were shorter than those in the control group(P<0.05）,hemorrhage([70.25±5.01]ml)in the observation group was lesser than those in the control group(76.00%)(P<0.05）;stone clearance rate of renal calculi in the observation group was 92.00%,which was higher than that of the control group(P<0.05）,and the total effective rate of renal calculi in the observation group was 92%higher than thosevof the control group of 70.00%,the differences were statistically significant (P<0.05）.Conclusion After the percutaneous nephrolithotomy lithotripsy for patients with nephrolithiasis,a significant effect can be achieved.It can reduce the complications of the patients,have short hospitalization time,less bleeding and short operation time.It can promote the patient to recover quickly after operation,which is worthy of application. 2018 Vol. 25 (28): 88-90 [Abstract] ( 111 ) HTML (34 KB)  PDF  (0 KB)  ( 22 ) 91 Clinical effect of percutaneous pedicle screw internal fixation combined with vertebroplasty in the treatment of osteoporotic spinal compression fractures of single vertebral body ZHONG Ming-liang;GUO Chao-yang;CHEN Qin;LIU Ning;LU Zhi-jun Objective To explore the clinical effect of percutaneous pedicle screw fixation combined with vertebroplasty in the treatment of osteoporotic spinal compression fractures of single vertebral body.Methods Sixty patients with osteoporotic spinal fractures treated in our hospital from March 2016 to March 2017 were selected as study subjects.According to the method of randomization of envelopes,they were divided into control group and observation group,with 30 cases in each group.The patients in the control group were treated with vertebroplasty alone.The observation group was treated with percutaneous pedicle screw fixation combined with vertebroplasty.The clinical effects of the two groups were compared.Results In the observation group,the excellent and good rate,Barthel score,vertebral body height recovery rate were higher than those in the control group,the Oswestry score,the VAS score,complication rate,vertebral body height compression rate were lower than those in the control group,and kyphosis angle was less than that in the control group (P<0.05).Conclusion Percutaneous pedicle screw fixation combined with vertebroplasty is effective in the treatment of patients with osteoporotic spinal fractures. 2018 Vol. 25 (28): 91-93 [Abstract] ( 123 ) HTML (38 KB)  PDF  (0 KB)  ( 33 ) 94 Application of 3D printing assisted precise operation combined with enhanced recovery after surgery in complex acetabular fractures XU Zhou-fa;XIAO Zhi-qing;ZHU Jin-zhong;WANG Ai-ming;WANG Feng-long Objective To explore the effect of the application of 3D printing assisted precise operation combined with enhanced recovery after surgery in complex acetabular fractures.Methods The data of 42 cases of acetabular fracture treated in our hospital from March 2013 to December 2017 were analyzed.The patients were divided into two groups according whether they used the 3D printing technology in preoperative design.Group A used 3D printing to assist preoperative design,while group B underwent routine CT three-dimensional reconstruction.ERAS with combination of traditional Chinese and Western medicine was used for postoperative rehabilitation.The operation time,intraoperative bleeding,24 hours VAS pain score after operation,postoperative Matta fracture reduction score,Majeed function score of last follow-up,and the complications were compared and analyzed.ResultsAll patients were followed up for6to40months,an average of 17.5 months.The time of operation in the group A was shorter than that in group B,intraoperative bleeding and the amount of blood transfusion in group A were significantly less than those in group B(P<0.05).The VAS score of 24 hours in group A after operation was lower than that in group B (P<0.05).There was no significant difference between the two groups in the good rates of postoperative Matta fracture reduction score and the final follow-up of the Majeed function score(P>0.05).There were no severe complications such as deep venous thrombosis and infection in the group A.In group B,3 cases of hemorrhagic shock appeared because of bleeding in the operation,stability after transfusions and shock treatment.Conclusion 3D printing assisted precision operation combined with enhanced recovery after surgery for complex acetabular fractures has a more accurate and safer feature.It can reduce operation time,reduce bleeding and blood transfusion,and reduce postoperative trauma response.It is worthy of clinical promotion. 2018 Vol. 25 (28): 94-96转99 [Abstract] ( 123 ) HTML (39 KB)  PDF  (0 KB)  ( 27 ) 97 Clinical effect of closed negative pressure drainage in the treatment of bone trauma XIE Jian-fa;PENG Ji-he;HUANG Shi-jun Objective To observe the clinical effect of closed negative pressure drainage in the treatment of bone trauma.Methods A total of 94 patients with bone trauma treated in our hospital from January 2012 to December 2016 were selected as the subjects,and divided into study group and comparsion group by random number table method,with 47 cases in each group.The study group was treated with closed negative pressure drainage.The comparison group was treated with routine dressing change.The clinical indexes,therapeutic effect and adverse reaction rate were compared and analyzed between the two groups.Results The number of changes of medicine,length of stay,hospitalization expenses,and healing time in the study group were better than those in the comparison group,and the differences were statistically significant(P<0.05).The total effective rate in the study group was higher than that in the comparison group,with significant statistical difference(P<0.05).The incidence of adverse reactions in the study group(6.38%)was lower than that in comparison group(25.53%),the difference was statistically significant(P<0.05).ConclusionTrauma patients with the clinical effect of closed negative pressure drainage treatment is better,which can shorten in-hospital time,avoid the occurrence of adverse reactions,for patient rehabilitation as soon as possible,and should be popularized and applied widely in the actual treatment. 2018 Vol. 25 (28): 97-99 [Abstract] ( 125 ) HTML (34 KB)  PDF  (0 KB)  ( 28 ) 100 Clinical effect of arthroscopic rotator cuff repair in the treatment of rotator cuff injury LIN Ren;QIU Jun-qin;LIN Wei Objective To explore the clinical effect of arthroscopic rotator cuff repair in the treatment of rotator cuff injury.Methods Thirty patients with rotator cuff injuries from January 2013 to January 2016 were selected as the subjects,and divided into two groups according to different therapeutic methods,with 15 cases in each group.In control group,open surgery was used,while in the observation group,arthroscopic rotator cuff repair was adopted.The effect of of rotator cuff repair,the healing time of rotator cuff injury,shoulder function,activity of daily living and pain before and after treatment were compared between the two groups.Results The hospital stay of the observation group was shorter than that of the control group,the postoperative drainage volume,incision length and blood loss in the observation group were significantly less than those in the control group,and the differences were statistically significant(P<0.05).The healing time of the rotator cuff injury of the observation group was shorter than that of the control group,with statistical significance(P<0.05).There was no great difference in shoulder function,activity of daily living or pain before treatment(P>0.05).After treatment,the shoulder function,activity of daily living and pain in the observation group were better than those in the control group,with statistical significance (P<0.05).Conclusion Arthroscopic rotator cuff repair is effective for the treatment of rotator cuff injury.It can effectively promote the healing of rotator cuff injuries,relieve pain,improve mobility and activity of daily living,and is worthy of application and promotion. 2018 Vol. 25 (28): 100-102 [Abstract] ( 118 ) HTML (34 KB)  PDF  (0 KB)  ( 30 ) 103 Clinical study of artificial double-action femoral head replacement in the treatment of femoral neck fracture in elderly patients ZHU Zhi-li;XIONG Shao-hua Objective To explore the clinical effect of artificial double-action femoral head replacement in the treatment of femoral neck fracture in elderly patients.Methods A total of 94 elderly patients with femoral neck fracture treated in our hospital from February 2015 to March 2017 were selected as the study subjects,and divided into two groups by lottery method,with 47 cases in each group.The control group was treated with open reduction and internal fixation,and the observation group used artificial double-action femoral head replacement for treatment.The rate of treatment,intraoperative blood loss,operative time,length of stay and the incidence of surgical complications were compared between the two groups.Results The excellent rate of treatment in the observation group(97.87%)was higher than that in the control group(74.47%),the difference was statistically significant(P<0.05).The amount of blood loss in the observation group was less than that in the control group,the difference was statistically significant(P<0.05).The operative time and living time of the elderly patient in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the observation group(2.13%)was lower than that in the control group (27.66%),the difference was statistically significant(P<0.05).Conclusion For elderly patients with femoral neck fracture choose double acting femoral head arthroplasty treated,in improving the rate of good treatment,reduce the intraoperative blood loss,shorten the operation time and hospital stay,reduce the surgical complications get exact effect,thereby promoting improved disease in elderly patients with femoral neck fracture and rehabilitation. 2018 Vol. 25 (28): 103-105 [Abstract] ( 123 ) HTML (33 KB)  PDF  (0 KB)  ( 27 ) 106 Comparison efficacy of reduction self-locking intramedullary nail and double plate fixation in the treatment of humeral shaft fracture LAI Fu-sheng Objective To explore the efficacy of reduction self-locking intramedullary nails and double-plate fixation in the treatment of humeral shaft fractures.Methods A total of 68 patients with humeral shaft fracture treated in our hospital from January 2017 to October 2017 were selected as the subjects,and divided into study group and control group by single and double digit table method,34 cases in each group.The control group was fixed with double plates,and the study group was fixed with reduction self-locking intramedullary nail.The clinical effects were compared between the two grups.Results The amount of intraoperative blood loss of the study group was significantly less than that in the control group(P<0.01).The operation time and postoperative fracture healing time of the study group were significantly lower than those of the control group(P<0.05).The postoperative pain,muscle strength and total score of Constant-Murley shoulder function score of the study group were significantly higher than the control group (P<0.05).The pain,active function and total score of hospital for special surgery score of the study group were significantly higher than those of the control group (P<0.05).Conclusion The reduction self-locking intramedullary nail compared with double plate fixation in the treatment of humeral shaft fracture has less blood loss during operation,short operation time,quick postoperative fracture healing,good postoperative shoulder and elbow joint function.It is worthy of application. 2018 Vol. 25 (28): 106-108转112 [Abstract] ( 126 ) HTML (38 KB)  PDF  (0 KB)  ( 30 ) 109 Effect of Rivaroxaban in prevention of post-operative deep venous thrombosis after intertrochanteric fracture of femur in elderly patients YAN Jian-hua;XIE Qing Objective To explore the effect of Rivaroxaban in prevention of post-operative deep venous thrombosis(DVT)after intertrochanteric fracture of femur in elderly patients.Methods Altogether 80 elderly patients with intertrochanteric fractures of femur who were treated in our hospital from November 2015 to April 2017 were selected as the subjects,and divided into two groups according to the random number table method,with 40 cases in each group.The Rivaroxaban group was treated with Rivaroxaban Tablets,while the low molecular weight heparin calcium(LMWHC)group were administered with injection of LMWHC.The coagulation indexes before operation and at postoperative 1 and 12 hours,including platelet(PLT),alanine aminotransferase(ALT)and activated partial thromboplastin time (APTT),as well as intra-operative hemorrhage,post-operative drainage and post-operative deep vein thrombosis(DVT)incidence of two groups were observed.Results The PLT and APTT levels of the two groups at post-operative 1 and 12 hours were lower than those before operation,and the ALT levels of the two groups was higher than that before operation,with statistically significant difference(P<0.05).There were no statistically significant differences in the levels of PLT,APTT and ALT between the two groups at post-operative 1 and 12 hours(P>0.05).There were no statistically significant differences in intra-operative hemorrhage and drainage volume between the two groups(P>0.05).All the patients were followed up for 6 months.The incidence of DVT of Rivaroxaban group was 2.5%,lower than that of LMWHC group,with statistically significant difference (P<0.05).Conclusion Application of Rivaroxaban in the treatment of elderly patients with intertrochanteric fracture of femur has little effect on coagulation function,and can significantly reduce the incidence of post-operative DVT. 2018 Vol. 25 (28): 109-112 [Abstract] ( 157 ) HTML (39 KB)  PDF  (0 KB)  ( 33 ) 113 Effect observation of dietary intervention on prevention of simple obesity in children WANG Shi-hua Objective To study the clinical effect of dietary intervention on the prevention of simple obesity in children.Methods Altogether 120 children with simple obesity who were admitted to our hospital from May 2016 to March 2017 were selected as the study subjects.They were randomly divided into the control group and the observation group according to the random number table method,with 60 cases in each group.The control group was given routine nursing intervention,and the observation group was given dietary intervention.The condition of simple obesity,body mass,body mass index and sebum thickness before and after intervention in two groups were compared.Results There was no significant difference in the obesity rate before the intervention between two groups(P>0.05).The obesity rate after the intervention in the observation group(38.33%)was lower than that before the intervention(60.00%),which was significantly lower than that in the control group (75.00%),and the differences were statistically significant(P<0.05).There was no significant difference in body mass,body mass index and sebum thickness before intervention between two groups(P>0.05).The body mass,body mass index and sebum thickness after the intervention in two groups were lower than those before intervention,and the differences were statistically significant(P<0.05).The body mass,body mass index and sebum thickness after the intervention in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Dietary intervention can accurately prevent simple obesity in children,and has a good clinical effect on childhood obesity,which is worthy of clinical promotion. 2018 Vol. 25 (28): 113-115 [Abstract] ( 114 ) HTML (36 KB)  PDF  (0 KB)  ( 28 ) 116 Clinical study on laparoscopic surgery and hysteroscopic surgery in the treatment of large type II submucosal fibroids ZHONG Bo-lin;ZHU Yan-ping;YANG Xing-ling;HUANG Gui-lian Objective To analyze the clinical effect of laparoscopic surgery and hysteroscopic surgery in the treatment of large typeⅡsubmucosal fibroids.Methods A total of 36 patients with 5-6 cm typeⅡsubmucosal fibroids who were admitted to our hospital from February 2017 to January 1818 were selected as subjects.According to the different treatment methods,they were divided into the control group and the study group,with 18 cases in each group.The control group was given hysteroscopic myomectomy,while the study group was given laparoscopic myomectomy.The surgical related indicators(operation time,intraoperative blood loss,hospitalization time,time of postoperative antibiotic use),complication rate and one-time surgical success rate were analyzed and compared between two groups.Results The operation time,hospitalization time and postoperative antibiotic use time in the study group were longer than those in the control group,the amount of intraoperative blood loss was more than that in the control group,and the differences were statistically significant(P<0.05).The total incidence rate of complications in the study group (5.56%)was lower than that in the control group(33.33%),and the difference was statistically significant(P<0.05).The one-time surgical success rate in the study group(100.00%)was higher than that in the control group(77.78%),and the difference was statistically significant(P<0.05).Conclusion Laparoscopic surgery can help improve the one-time surgical success rate and reduce complications in the patients with large typeⅡsubmucosal fibroids.However,hysteroscopic surgery can effectively save the operation time,reduce the amount of intraoperative blood loss,and shorten the length of hospital stay.Therefore,in practical work,the treatment plan can be decided according to the patients′condition and willingness. 2018 Vol. 25 (28): 116-118转125 [Abstract] ( 138 ) HTML (38 KB)  PDF  (0 KB)  ( 24 ) 119 Effect comparison of Omeprazole for children with peptic ulcer in different courses of treatment JIANG Ling;LIU Xiao-ming Objective To compare the effect of Omeprazole for children with peptic ulcer in different courses of treatment.Methods Sixty pediatric patients admitted to our hospital from January 2016 to June 2017 were selected as subjects.According to C urea breath test(14C-UBT),the test results were classified into HelicobaCter pylori(Hp)positive group (n=40)and HP negative group (n=20).In the Hp negative group,they were further divided into group A and group B with 10 cases in each group.In the Hp positive group,they were also further divided into group C and group D with 20 cases in each group.For Hp negative group,oral administration of Omeprazole for 2 weeks in group A was performed,while 4 weeks in group B.For Hp positive group,children in group C were given Omeprazole,Amoxicillin Clavulanate Potassium and Clarithromycin for 2 weeks.After treatment with Omeprazole,Amoxicillin Clavulanate Potassium and Clarithromycin for 2 weeks in group D,antibiotics were discontinued and Omeprazole was continued for 2 weeks.The Hp-positive group and the Hp negative group were all examined in our hospital after stopping the drug for 4 weeks.The Hp positive group was also tested by14C-UBT.The total effective rate of treatment and the incidence of adverse drug reactions were compared between two groups and14C-UBT in Hp positive group was compared.Results There were no significant differences in the total effective rate of treatment and the incidence of adverse drug reactions between group A and group B(P>0.05).There were no significant differences in the total effective rate of treatment and the incidence of adverse drug reactions between group C and group D (P>0.05).There was no significant difference in 1 4 C-UBT between group C and group D (P>0.05).Conclusion The study intends to provide a short course of treatment for children with peptic ulcer by comparing the comprehensive curative effect of 2 weeks and 4 weeks,increasing compliance,reducing side effects of drugs,and reducing economic burden for children′s parents,which has good social and economic benefits. 2018 Vol. 25 (28): 119-121 [Abstract] ( 125 ) HTML (37 KB)  PDF  (0 KB)  ( 29 ) 122 Clinical effect of cervical balloon combined with Oxytocin in the induction of labor in the late pregnancy ZHANG Hong-hua;LIANG Dong-ru;Ma Li-Qin Objective To investigate the clinical effect of cervical balloon combined with Oxytocin in the induction of labor in the late pregnancy.Methods One hundred pregnant women with induced labor in the late pregnancy who were admitted to our hospital from January 1st,2016 to December 31st,2017 were selected as subjects.They were divided into control group (n=50)and study group (n=50)according to single month and double month combined with the patients′own wishes.The control group received intravenous infusion of small dose of Oxytocin,and the study group received cervical balloon on the basis of the control group.The total effective rate of cervical maturation,the cervical Bishop scores before and after cervical maturation,the induction of labor and the total incidence of adverse reactions were compared between two groups.Results The effective rate of cervical maturation in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the cervical Bishop scores before cervical maturation between two groups(P>0.05).The cervical Bishop scores after cervical maturation in two groups were higher than those before cervical maturation,and the differences were statistically significant(P<0.05).The cervical Bishop scores after cervical maturation in the study group were higher than those before cervical maturation,and the difference was statistically significant(P<0.05).The frequency of medication,the incidence of postpartum hemorrhage,and the rate of cesarean section in the study group were lower than those in the control group,the total labor time was shorter than that in the control group,the incidence of vaginal delivery was higher than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between two groups(P>0.05).Conclusion The combination use of cervical balloon and Oxytocin is effective in the induction of labor in the late pregnancy,and the incidence of adverse reactions is low,which has high safety in treatment.It is worthy of promotion and application. 2018 Vol. 25 (28): 122-125 [Abstract] ( 157 ) HTML (37 KB)  PDF  (0 KB)  ( 20 ) 126 Clinical effect of Norethisterone combined with Gynecological Yangrong Capsules in the treatment of menopausal functional uterine bleeding ZHOU Hai-gen;HE Zhi-yuan;LI Li Objective To investigate the clinical effect of Norethisterone combined with Gynecological Yangrong Capsules in the treatment of menopausal functional uterine bleeding.Methods A total of 52 patients with menopausal functional uterine bleeding treated in our hospital from January 2017 to April 2018 were selected as the subjects.They were divided into the control group and the study group according to the random number table method,26 cases in each group.The control group was treated with Norethisterone,and the study group was treated with Norethisterone combined with Gynecological Yangrong Capsules.The total effective rate,clinical indicators(blood control time,complete hemostasis time,estradiol[E2],follicle stimulating hormone[FSH],endometrial thickness)and the total incidence of adverse reactions were compared between two groups.Results The total effective rate in the study group was 96.1%,which was higher than that in the control group (80.8%),and the difference was statistically significant(P<0.05).The bleeding control time and complete hemostasis time in the study group were shorter than those in the control group,the levels of E2and FSH and endometrial thickness were higher than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between two groups(P>0.05).Conclusion The curative effect of of Norethisterone combined with Gynecological Yangrong Capsules in the treatment of menopausal functional uterine bleeding is satisfactory,which is worthy of clinical promotion and application. 2018 Vol. 25 (28): 126-128 [Abstract] ( 149 ) HTML (35 KB)  PDF  (0 KB)  ( 19 ) 129 Clinical significance of peripheral blood EOS,total IgE,IL-10 and induced sputum EOS in wheezing assessment of recurrent wheezing infants MA Qian-jin;WU Yi;CHEN Tao;SHA Guang-qun;GENG Wei;XUE Kui Objective To investigate the clinical significance of peripheral blood eosinophils(EOS),total IgE,interleukin-10(IL-10)and induced sputum EOS in wheezing assessment of recurrent wheezing infants.Methods A total of 40 cases of recurrent wheezing infants treated in people′s hospital in Pizhou city from February 2016 to December 2017 were randomly selected as objects and divided into API positive group(n=20)and API negative group(n=20)according to the asthma prediction index(API).In the same period,altogether 20 healthy infants with the health checkup in people′s hospital in Pizhou city were randomly selected as control group (n=20).Serum total IgE levels were measured by electrochemiluminescence method.Serum IL-10 levels were detected by chemiluminescence method.Peripheral blood EOS counts and the proportion of induced sputum EOS were detected by HE staining.Results The peripheral blood EOS counts,T-IgE levels and the proportion of induced sputum EOS in the API positive group were higher than those in the API negative group and the control group,the level of serum IL-10 was lower than that in the API negative group and the control group,and the differences were statistically significant(P<0.05).The level of serum IL-10 in the API negative group was higher than that in the control group,and the difference was statistically significant(P<0.05).There were no significant differences in the peripheral blood EOS counts,T-IgE levels and the proportion of induced sputum EOS between the API negative group and the control group (P>0.05).Serum IL-10 was negatively correlated with total IgE and induced sputum EOS(r=-0.394,P<0.05;r=-0.659,P<0.05).Total IgE was positively correlated with induced sputum EOS (r=0.492,P<0.05).Peripheral blood EOS was negatively correlated with IL-10,and positively correlated with total IgE and induced sputum EOS (r=-0.668,P<0.05;r=0.445,P<0.05;r=0.521,P<0.05).Conclusion The peripheral blood EOS counts,T-IgE levels and the proportion of induced sputum EOS increase,and IL-10 levels decreas in infants with API positive recurrent wheezing.There is a correlation between the peripheral blood EOS,TIgE,induced sputum EOS and IL-10 levels and API,which has a good reference value in predicting the risk of asthma. 2018 Vol. 25 (28): 129-132 [Abstract] ( 153 ) HTML (44 KB)  PDF  (0 KB)  ( 141 ) 133 Clinical analysis of recurrent vaginal delivery after cesarean section scar YANG Qiu-sheng Objective To explore the clinical experience of vaginal safe delivery of re-pregnancy puerpera after cesarean section.Methods One hundred and twenty-six cases of full-term puerpera after cesarean section admitted to our hospital from January 2015 to March 2018 were selected as objects.Among them,47 cases were eligible for vaginal production and were willing to perform the vaginal trial production,and 36 cases of them with successful vaginal production were enrolled in the study group and the remaining 90 puerpera with recurrent cesarean section were enrolled in the control group.The hospitalization costs,the incidence of postpartum hemorrhage within 24 h (≥500 ml),puerperal morbidity,and neonatal asphyxia of two groups were compared.Results Forty-seven puerpera were eligible for vaginal trial production and were willing to perform the vaginal trial production,36 puerpera of them had successful vaginal trial production(76.6%),and no uterine rupture occurred.The hospitalization cost of the study group was significantly less than that of the control group,and the difference was statistically significant(P<0.05).The incidence rates of postpartum hemorrhage within 24 h (≥500 ml)and puerperal morbidity in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of neonatal asphyxia between two groups(P>0.05).Conclusion In the case of fully grasping the contraindications,precautions and indications of vaginal delivery after cesarean section,vaginal delivery can reduce hospitalization cost and complications,which is worthy of clinical application. 2018 Vol. 25 (28): 133-135 [Abstract] ( 124 ) HTML (35 KB)  PDF  (0 KB)  ( 27 ) 136 Application effect of hormone replacement therapy combined with Kuntai Capsule in the treatment of premature ovarian failure KANG Sheng-qi Objective To explore the application effect of hormone replacement therapy combined with Kuntai Capsule in the treatment of premature ovarian failure.Methods A total of 70 patients with premature ovarian failure treated in our hospital from January 2016 to January 2018 were selected as objects and they were divided into the control group(34 cases)and the observation group (36 cases)according to the random number table method.The control group received hormone replacement therapy,and the observation group received Kuntai Capsule on the basis of the control group.The total effective rate of treatment for premature ovarian failure and the levels of sex hormone (luteinizing hormone[LH],follicle stimulating hormone[FSH],estradiol[E2])before and after treatment and the total rate of adverse reactions were compared between two groups.Results The total effective rate of treatment for premature ovarian failure in the observation group was 88.9%,which was significantly higher than that in the control group (67.6%),and the difference was statistically significant(P<0.05).There were no significant differences in the levels of sex hormone before treatment between two groups(P>0.05).The levels of LH and FSH after treatment in two groups were lower than those before treatment,the level of E2was higher than that before treatment,and the differences were statistically significant(P<0.05).The level of FSH in the observation group was significantly lower than that in the control group,the level of E2was significantly higher than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between two groups (P>0.05).Conclusion Kuntai Capsule assisted hormone replacement therapy for the treatment of premature ovarian failure can improve the efficiency of treatment,improve the level of sex hormone,and doesn′t increase the incidence of adverse reactions,which is worthy of clinical application. 2018 Vol. 25 (28): 136-138 [Abstract] ( 134 ) HTML (37 KB)  PDF  (0 KB)  ( 28 ) 139 Clinical effect of application of early intervention in the treatment of premature infants with brain injury LIU Qi-yun;QU Yun-ping;MA Li Objective To explore the clinical effect of application of early intervention in the treatment of premature infants with brain injury.Methods Altogether 100 cases of premature infants with brain injury who were treated in our hospital from January 2014 to April 2015 were selected as the objects of this research and divided into the intervention group(n=50)and the control group(n=50)according to the random number table method.The control group was given the routine comprehensive treatment,while the intervention group was given the intervention treatment on the basis of the control group at one month after birth and was followed up regularly via phone and visits.The extinction time of subependymal cyst was judged by the results of head B-mode ultrasonography.The development assessment of two groups was performed by using Gesell developmental schedule.The imaging examination results at 6 months,the neurological abnormalities at 6-12 months,the MDI and PDI scores at 6,12,and 24 months,and the neurological outcome at the age of 3 were compared between two groups.Results There was no statistically significant difference in the results of head magnetic resonance imaging(MRI)and head computed tomography(CT)at 6 months after birth between two groups(P>0.05).The total incidence of neurological abnormalities at 6-12 months after birth in the intervention group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).The scores of MDI and PDI at 6,12,and 24 months after birth in the intervention group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).The total incidence of neurological prognosis at the age of 3 in the intervention group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Early intervention therapy has significant benefits to improve the symptoms of brain injury in premature infants.It can effectively promote the normal physical and intelligent development of premature infants,improve their quality of life,and have important significance for their future growth and development. 2018 Vol. 25 (28): 139-142转148 [Abstract] ( 120 ) HTML (44 KB)  PDF  (0 KB)  ( 24 ) 143 Effect study of ultrasound-guided nerve block in the treatment of facial neuralgia GUO Yan;WANG Qian;DAI Li-ping Objective To investigate the effect and value of ultrasound-guided nerve block in the treatment of pain.Methods Eighty patients with facial neuralgia admitted to our hospital from November 2014 to November 2017 were selected as the subjects,and divided into observation group and reference group according to the treatment methods,with 40 cases in each group.In the observation group,ultrasound-guided nerve block therapy was performed,and in the reference group,conventional nerve block was used.The therapeutic effect of the two groups was compared.Results The success rate of block in the observation group was significantly higher than that of the reference group (P<0.05).The time consumption in the observation group was shorter than that in the reference group,and depth of needle insertion in the observation group was less than that in the reference group(P<0.05).The NRS scores of the two groups decreased significantly after treatment,and the NRS scores in the observation group were significantly lower than that of the reference group (P<0.05).The total effectiveness rate in the observation group was higher than that in the reference group,and adverse reactions in the observation group was lower than that in the reference group,the differences were statistically significant(P<0.05).ConclusionUltrasound-guided nerve block therapy is simple in the treatment of pain with a high success rate of block,safe and effective. 2018 Vol. 25 (28): 143-145 [Abstract] ( 162 ) HTML (37 KB)  PDF  (0 KB)  ( 31 ) 146 Value analysis of spiral CT examination for lung cancer diagnosis HONG Fang-ming;WEN Xiao-liang;HUANG Xiao-lin;XIE Xiao-zhen;DENG Ling-ling Objective To investigate the value of spiral CT in the diagnosis of lung cancer.Methods Seventy-eight patients with lung cancer from February 2015 to March 2018 treated in our department were selected as the subjects.All patients were performed with spiral CT examinations.Spiral CT scans were performed to analyze the abnormalities of lung cancer,pathological types,and clinical staging results.Results The detection rates of lung cancer wall thickening,extraluminal/intraluminal lesions,obstructive lesions and metastatic changes by spiral CT examinations were 48.7%,51.3%,59.0%,12.8%,which was not significantly different from those by pathological examinations for 51.3%,52.6%,60.3%and 15.4%(P>0.05).Among 78 patients,76 cases of lung cancer were detected by spiral CT.The detection rate of lung cancer by spiral CT was 97.4%,and the missed diagnosis rate was 2.6%.The diagnostic accuracy of spiral CT examinations for central lung cancer,peripheral lung cancer and diffuse lung cancer,and the total accuracy were 100.0%,97.3%,85.7%and 97.4%compared with 100.0%,100.0%,100.0%and 100.0%for pathological examinations(P>0.05).The accuracy of spiral CT detection in stageⅠ,Ⅱ,Ⅲ andⅣ lung cancer,and the total accuracy were 95.7%,100.0%,100.0%,100.0%and 97.4%in comparison with the pathological examination results of 100.0%,100.0%,100.0%,100.0%and 100.0%,which didn′t display great difference(P>0.05).Conclusion Spiral CT is effective in diagnosing lung cancer,and the rate of missed diagnosis is low. 2018 Vol. 25 (28): 146-148 [Abstract] ( 143 ) HTML (32 KB)  PDF  (0 KB)  ( 20 ) 149 Clinical value of spectral CT reconstruction and 64-slice spiral CT reconstruction in evaluating carotid plaque WANG Su-yan Objective To explore the clinical value of spectral CT reconstruction and 64-slice spiral CT reconstruction with assessing carotid plaque.Methods A total of 40 cases with ischemic cerebral apoplexy treated in our neurology clinic from January to December 2017 were selected as the subjects.All patients underwent dual-spectrum CT reconstruction and conventional 64-slice CT reconstruction.The observation group used reconstructive model and the control group used 64-slice CT reconstruction model.Then the doses and radiation doses with the contrast agents between the two groups were compared.The stenosis and the level of the contrast agents in the plaques were compared.The plaque hemorrhage and fibrous cap rupture rate between the two groups were counted.Results The dose of contrast agent in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The radiation dose in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The stenosis rate in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).The level of contrast agent in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The percentage of plaque hemorrhage and fibrous cap rupture in the observation group were significantly higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion For carotid plaque formation,spectra CT reconstruction has less contrast agent dose and radiation dose received,which can effectively determine the carotid lumen stenosis and plaque lesions.It has the advantages of high diagnostic sensitivity,and it is a safety and reliability method. 2018 Vol. 25 (28): 149-151 [Abstract] ( 128 ) HTML (35 KB)  PDF  (0 KB)  ( 30 ) 152 Application value of multi-slice spiral CT in the diagnosis of benign and malignant thyroid nodules FU Zhi-ying;WAN Hong;CHEN Liang Objective To study the application value of multi-slice spiral CT in the diagnosis of benign and malignant thyroid nodules.Methods The medical data of 74 patients with thyroid nodules who were given comprehensive examination diagnosed in our hospital from May 2016 to January 2017 were retrospectively analyzed.Among them,57 cases were benign thyroid nodules,and 17 cases were malignant thyroid nodules.All patients were given multi-slice spiral CT plain scan combined with enhanced scan.According to the results of CT imaging,the CT features of benign and malignant thyroid nodules were diagnosed and differentiated.Results According to the multi-slice spiral CT examination,the benign thyroid nodules was detected in 57 cases(75.68%).The malignant thyroid nodules was detected in 57 cases (22.97%).Among them,the CT findings of benign thyroid nodules were mostly regular in shape,with clear boundaries and curve-like and patch-like calcifications.CT findings of malignant thyroid nodules were mostly irregular in shape,blurred in borders,and with spot and particle-like calcification,there were statistically significant differences in CT features between benign and malignant thyroid nodules(P<0.05).The CT enhancement features of benign thyroid nodules were mostly uniform enhancement,with a few of complete ring enhancements,while malignant thyroid nodules were mostly peritumoral residual ring enhancement and peninsula-like enhancement,the differences were statistically significant(P<0.05).Conclusion Multi-slice spiral CT is highly accurate in the diagnosis of benign and malignant thyroid nodules,and can accurately observe the specific characteristics of benign and malignant nodules.It provides an important reference for clinical diagnosis and follow-up treatment,and has a high clinical promotion value. 2018 Vol. 25 (28): 152-154 [Abstract] ( 137 ) HTML (32 KB)  PDF  (0 KB)  ( 22 ) 155 Clinical effect of point-pressing massage with syndrome differentiation of six meridians manipulation in treatment of lumbar disc herniation LIAO Xin-xiang;FENG Guang-ge;ZHOU Yi-qing Objective To study the clinical effect of point-pressing massage of syndrome differentiation of six meridians manipulation in treatment of lumbar disc herniation.Methods Altogether 200 in-patients who were treated in our department from January 2015 to December 2016 were selected and the patients were grouped according to their admission number(double day was treatment group,single day was control group),and there were 100 cases in each group.The treatment group was treated with point-pressing massage with syndrome differentiation of six meridians manipulation,and the control group was treated with general massage manipulation.Clinical effect between the two groups was compared.Results The marked improvement rate and recovery rate of straight leg elevation of the treatment group 1-week after treatment were higher than those of the control group(P<0.05).The total effective rate of the treatment group and the control group was 97.0%and 79.0%respectively,and there was a statistically difference between the two groups(P<0.05).Conclusion Effect of point-pressing massage with syndrome differentiation of six meridians manipulation applied in treatment of lumbar disc herniation is better than ordinary massage therapy.Point-pressing massage with syndrome differentiation of six meridians manipulation in treatment of lumbar disc herniation is of great popularization value. 2018 Vol. 25 (28): 155-157 [Abstract] ( 167 ) HTML (38 KB)  PDF  (0 KB)  ( 24 ) 158 Clinical effect of Ephedra，Asarum and Aconite Decoction treating allergic rhinitis FENG Shao-Bin;KE Zun-Bin;LUN Xiao-Chuan Objective To discuss the clinical effect of Ephedra，Asarum and Aconite Decoction treating allergic rhinitis.Methods All of 96 patients with allergic rhinitis treated in our hospital from January 2016 to October 2017 were randomly divided into the two groups,and there were 48 cases in each group.The control group was treated with Loratadine,and the experimental group was treated with Ephedra，Asarum and Aconite Decoction.The clinical efficacy,immune function and quality of life between the two groups were compared.Results The total effective rate and cure rate of patients in the experimental group was 95.8%and 50.0%respectively,which were higher than those of the control group(77.1%,25.0%),and the differences were statistically significant(P<0.05).4 and 8 weeks after treatment,the levels of CD3,CD4,CD8 cells and quality of life scores of the experimental group were increased and were higher than those of the control group(P<0.05).Conclusion The effect of Ephedra，Asarum and Aconite Decoction treating allergic rhinitis is good,and it has high clinical effective rate,and can improve the body′s immune function and quality of life.It is worthy of clinical choice. 2018 Vol. 25 (28): 158-160 [Abstract] ( 121 ) HTML (35 KB)  PDF  (0 KB)  ( 33 ) 161 Application of continuous intervention of auricular points compression and internet information interviewing in diabetic patients nursing LIU Yang-juan;MEI Ping-xia;SHI Gui-ying Objective To analyze the application effect of consecutive interventions of acupuncture and pressing network in the treatment of patients with diabetes.Methods A total of 193 patients with diabetes who were hospitalized during the period from June 2015 to September 2017 in Hukou County People′s Hospital,Jiangxi Province were observed.They were divided into control group (96 cases)and experimental group(97 cases)by random number table method,，the control group was given routine care.On this basis,the experimental group was given a continuous intervention of auricular pressure bean+network information interview,and was compared the effect of the two groups of care.Results After nursing,the total compliance rate of dietary self-management compliance (96.91%)was higher in the experimental group than in the control group(81.25%),the difference was statistically significant(P<0.05）.The improvement of blood glucose level in the experimental group was better than that in the control group,there was statistical significance (P<0.05）.Conclusion The application of continuous intervention of ear acupuncture and pressing network informatization visits has significant effect.It can effectively improve the dietetic self-management compliance of diabetic patients and maintain ideal blood glucose level.The prognosis is good. 2018 Vol. 25 (28): 161-163 [Abstract] ( 135 ) HTML (34 KB)  PDF  (0 KB)  ( 28 ) 164 Effect of nursing intervention on insulin treatment of gestational diabetes mellitus FAN You-hua;WU Mei-ling;XU Xi-xi;WANG Cai-yi Objective To investigate the effect of nursing intervention in the treatment of gestational diabetes with insulin.Methods A total of 100 cases of gestational diabetes treated in our hospital from June 2016 to December 2017 were the subjects of this study.They were randomly divided into control group and observation group according to the order of visits,50 cases in each group.The patients in the control group were treated with insulin,and the patients in the observation group were treated with insulin nursing intervention.After the study was completed,the blood glucose changes,insulin dosage,blood glucose attainment time,neonatal status,and complication rate were compared between the two groups.Results After treatment,the blood glucose level in the observation group was lower than that in the control group(P<0.05）.The preterm birth rate,meconium contamination rate,and neonatal huge rate were all lower than those in the control group(P<0.05）.The observation group had less insulin than the control group,and the blood glucose reaching time was shorter than the control group,the total incidence of complications was lower than the control group,the differences were statistically significant(P<0.05）.Conclusion Nursing intervention has a significant effect in the treatment of gestational diabetes mellitus with insulin,which can improve the blood glucose level of patients and is worthy of clinical application. 2018 Vol. 25 (28): 164-166 [Abstract] ( 126 ) HTML (35 KB)  PDF  (0 KB)  ( 24 ) 167 Nursing effect of ambulance remote video monitoring system in pre-hospital emergency care WU Xiao-hua;ZHONG Fang-yu;LI Jin-mei;DENG Xiu-pin;XIAO Ting-ting Objective To study the nursing effect of ambulance remote video monitoring system (RVMS)in the prehospital emergency care.Methods From June to December in 2016,17 085 assessment files of nursing quality control without ambulance RVMS and 18 736 nursing quality control assessment files with ambulance RVMS from January to June in 2017 were analyzed.The quality of care and satisfaction of nursing before and after applying ambulance RVMS were compared.Results After application,the total score of nursing service quality was significantly higher than that before (P<0.05）.The total satisfaction degree after treatment was 94.90%,higher than that before accounting for 92.03% (P<0.05）.Conclusion In the pre-hospital emergency nursing quality control,application of the ambulance RVMS can cover the blind spots that are difficult to control,and guide and control the key links in the pre-hospital emergency care.Video real-time monitoring plays a role in urging first-aid nurses.The prompt reminding on inappropriate operation from the full-time quality control nurses can correct the nursing,prevent the occurrence of safety hazards to large extent,and effectively improve the nursing quality of pre-hospital first aid. 2018 Vol. 25 (28): 167-169 [Abstract] ( 123 ) HTML (33 KB)  PDF  (0 KB)  ( 27 ) 170 Application of multiple forms of health education in patients with epilepsy GU Rui-xin Objective To explore the effect of various forms of health education on epilepsy patients.Methods Sixty patients undergoing treatment in our hospital from August 2015 to December 2016 were selected.According to the nursing methods,they were divided into control group and observation group,30 cases in each group.The control group was given routine nursing.The observation group was given various forms of health education on the basis of the control group.The SDS and SAS scores,quality of life,and nursing satisfaction were compared between the two groups.Results There was no significant difference in SAS and SDS scores between the two groups before intervention (P＞0.05）;SAS and SDS scores in the observation group after intervention were lower than those in the control group (P<0.05）;observation group intervention after the quality of life was better than the control group，the difference was statistically significant(P<0.05）;the total satisfaction of the observation group after intervention was 96.7%,higher than that in the control group,the difference was statistically significant(P<0.05）.Conclusion Health education in various forms has a positive effect in improving the negative emotion of epileptic patients.It can not only improve the anxiety of the patients,but also improve the quality of life and nursing satisfaction of the patients.It is worth popularizing in clinical practice. 2018 Vol. 25 (28): 170-172 [Abstract] ( 117 ) HTML (34 KB)  PDF  (0 KB)  ( 30 ) 173 Application effect of cluster nursing in elderly patients with femoral neck fracture operation XU Jin-lan Objective To explore the application effect of cluster nursing in elderly patients with femoral neck fracture.Methods 160 elderly patients with femoral neck fracture admitted in our hospital from September 2014 to September 2017 were selected.According to the different nursing methods,the patients were divided into observation group and control group,80 cases in each group.The patients in the control group were given general nursing,and the patients in the observation group were given cluster nursing,and the bed time,the time of infusion,the duration of moderate and above pain,the time of hospitalization,and the satisfaction of the patients to the nursing care were compared.between two groups.Results In the observation group,the bed time was(5.1±1.0)d,infusion time was(5.6±1.5)d,continuous severe pain time was(9.5±2.6)d,hospitalization time was(17±3.1)d,and the time of diagnosis and treatment were significantly shorter than those of the control group,the differences were statistically significant(P<0.05）.Of the 80 patients in the observation group,76 cases were satisfactory,3 cases were basically satisfactory and 1 were dissatisfied.The total satisfaction rate of nursing was 98.15%,which was significantly higher than that of the control group 83.33%.The difference was statistically significant(P<0.05）.Conclusion For the elderly patients with femoral neck fracture,cluster care can effectively relieve the pain,shorten the time of hospitalization and bed,and improve the patient′s satisfaction with the nursing. 2018 Vol. 25 (28): 173-175 [Abstract] ( 104 ) HTML (33 KB)  PDF  (0 KB)  ( 23 ) 176 Application effect of regular health education in the treatment of epilepsy patients DING Xi-lian Objective To explore the effect of regular health education on the treatment compliance and social function rehabilitation of epileptic patients.Methods60 epileptic patients in our hospital from May 2014 to April 2017 were collected and randomly divided into intervention group and control group,30 cases in each group.The patients in the control group were treated with epileptic drugs and general interpretation,and the patients in the intervention group were given regular health education on the basis of drug treatment.The treatment compliance and the degree of social function recovery were compared between the two groups.Results After intervention,the compliance rate and total compliance rate of the intervention group were significantly higher than those of the control group(P<0.05）.During the follow-up period,the total effective rate of the intervention group was significantly higher than that of the control group(P<0.05）.Conclusion Health education can effectively improve the compliance of the patients with epilepsy,reduce the recurrence rate and improve the prognosis.It is worthy of clinical promotion and application. 2018 Vol. 25 (28): 176-178 [Abstract] ( 129 ) HTML (36 KB)  PDF  (0 KB)  ( 33 ) 179 Application effect of primary nursing combined with APN scheduling flat management mode in nursing of hepatological surgery department MAO Xiao-ying;WU Jie;GONG Li-jiang Objective To investigate the application effect of primary nursing combined with APN scheduling flat-type management in nursing of hepatological surgery department.Methods 120 patients in the hepatological surgery department of Shangrao Second People′s Hospital from April 2017 to May 2018 were selected.The patients with primary nursing from April to October 2017 were selected as control group,and the patients with primary nursing combined with APN scheduling flat-type management from November 2017 to May 2018 were selected as observation group,60 cases in each group.The nursing effects,nursing trust and satisfaction,nursing quality were compared between the two groups.Results The disease cognition level,nursing trust and satisfaction,qualified rate of basic nursing,qualified rate of critical nursing,implementation rate of health education,qualified rate of nursing record sheets,qualified rate of quality inspection in observation group ([94.41±3.23])points,([97.35±1.27])points,100.00%,98.33%,98.33%,100.00%,100.00%)were higher than those in control group,and there were statistical difference(P<0.05）.Conclusion Primary nursing combined with APN scheduling flat-type management in nursing of hepatological surgery department can increase the patients′disease cognition,strengthen nursing trust and satisfaction and promote nursing quality. 2018 Vol. 25 (28): 179-181 [Abstract] ( 122 ) HTML (36 KB)  PDF  (0 KB)  ( 31 ) 182 Effect of comprehensive nursing intervention on quality of life in patients with primary pulmonary hypertension HUO Xue-qin;WANG Jian-ning;YAN Qiong Objective To explore the effect of comprehensive nursing intervention on quality of life in patients with primary pulmonary hypertension.MethodsAltogether 44 primary pulmonary hypertension patients who were treated in department of cardiology our hospital from January 2017 to January 2018 were divided according to the random digital table method into the control group and the experiment group,22 cases in each group.The experiment group was received comprehensive nursing intervention,while the control group was received routine nursing.The SF-36 scale was used to investigate the quality of life of the two groups.Results The post-interventional scores of all dimensions of quality of life of the experiment group were higher than those of the control group,with statistically significant difference(P<0.05）.The post-interventional scores of all dimensions of the quality of life of the experiment group were higher than those before the intervention,with statistically significant difference(P<0.05）.Conclusion Active and comprehensive nursing intervention measures can effectively improve the quality of life of patients with pulmonary hypertension,and provide a scientific basis for clinical nursing workers to formulate effective health education strategies. 2018 Vol. 25 (28): 182-184 [Abstract] ( 127 ) HTML (35 KB)  PDF  (0 KB)  ( 33 ) 185 Application effect of evidence-based nursing in patients with hypertension GONG Li-mei Objective To explore the application effect of evidence-based nursing in negative emotions of hospitalized patients with hypertension.Methods 106 cases of hypertension patients in our hospital from March 2017 to March 2018 were selected as the research object.According to the random number table method,the patients were divided into the control group and the observation group,53 cases in each group.The control group was received routine nursing,while the observation group was received evidence-based nursing intervention.The effects of SAS,SDS score,incidence of adverse events and nursing satisfaction on the two groups were compared.ResultsBefore intervention,there was no significant difference in the scores of SAS and SDS in the two groups(P＞0.05）;the scores of SAS and SDS in the two groups after intervention were significantly lower than those in the control group(P<0.05）;the total incidence of adverse events in the observation group was 3.77%(2 cases)significantly lower than that of the control group(18.87%)(10 cases),and the difference was statistically significant(P<0.05）.The total nursing satisfaction(96.23%)in the observation group was significantly higher than that in the control group(77.35%),and the differences were statistically significant(P<0.05）.Conclusion Evidence-based nursing intervention can effectively eliminate negative emotions in patients with hypertension,avoid the occurrence of adverse events,and also improve the satisfaction of patients to nursing service. 2018 Vol. 25 (28): 185-187 [Abstract] ( 108 ) HTML (36 KB)  PDF  (0 KB)  ( 31 ) 188 Application effect of comprehensive nursing intervention in patients of the intensive care unit YE Qiong-yao Objective To explore the application effect of comprehensive nursing intervention in intensive care unit(ICU)patients.Methods 80 Critically ill patients admitted from February 2016 to March 2018 were randomly divided into the control group and the observation group,40 cases in each group.The control group was received routine nursing intervention,and the observation group was received comprehensive nursing intervention,the two groups of comfort scores,anxiety scores,depression scores and nursing satisfaction were compared.Results After nursing,the scores of comfort in both groups were significantly higher than those before nursing (P＜0.05）.The scores of anxiety and depression in both groups were lower than those before nursing (P＜0.05）,while the scores of comfort in observation group were higher than those in control group (P＜0.05）,and the scores of anxiety and depression were lower than those of control group (P＜0.05）.The total satisfaction rate of nursing in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05）.Conclusion Comprehensive nursing intervention for ICU patients can effectively improve their comfort,reduce their anxiety and depression,and improve their satisfaction with ICU nursing. 2018 Vol. 25 (28): 188-190 [Abstract] ( 131 ) HTML (34 KB)  PDF  (0 KB)  ( 24 ) 191 Effect of detail management on pregnancy outcome of women with polycystic ovary syndrome undergoing assisted reproductive therapy HUANG Jin Objective To analyze the effect of detail management on pregnancy outcome of women with polycystic ovary syndrome （PCOS） assisted reproductive treatment.Methods 80 cases of PCOS in our hospital from January 2014 to January 2017 were selected as the subjects.They were dividev into the control group and the observation group according to random number table method,40 cases in each group.The control group was treated with routine nursing,and the observation group was treated with detail management.The pregnancy outcome was compared between the two groups.Results There was no significant difference in the incidence of pregnancy,abortion rate and pregnancy induced hypertension between two groups(P＞0.05）,and the rate of gestational diabetes and premature delivery in the observation group was lower than that of the control group (P<0.05）.The SAS score and SDS score of the observation group were lower than those of the control group after nursing,the differences were statistically significant(P<0.05）.Conclusion The use of detail management for the patients with polycystic ovary syndrome receiving reproductive treatment can increase the chance of pregnant women to help pregnant and reduce the complications of pregnancy,and the effect is significant. 2018 Vol. 25 (28): 191-193 [Abstract] ( 136 ) HTML (33 KB)  PDF  (0 KB)  ( 25 ) 194 The Influence about holistic nursing of body and mind on negative emotions and daily living ability in elderly patients with acute cerebral infarction LIU Hui-zhen Objective To investigate the application value of holistic nursing of body and mind in elderly patients with acute cerebral infarction and to observe its effects on negative emotions and daily living ability.Methods From January 2016 to November 2017,eighty elderly patients with acute cerebral infarction treated in our hospital were selected in the study and randomly divided into control group and observation group according to random number table method,40 cases in each group.The control group was received routine nursing,while the observation group was integrated with physical and mental holistic nursing intervention.A month later,negative emotion scores and activities of daily living were compared between the two groups.Results After the intervention,scores of self-rating depression scale(SDS)and anxiety self-rating scale (SAS)in the observation group were significantly lower than those in the control group (P<0.05）.Meanwhile the activity of daily life (ADL)scores were higher than the control group,while NIHSS scores were more lower than the control group,the differences were statistically significant(P<0.05）.Conclusion The physical and mental holistic nursing intervention can effectively improve the negative emotions and the daily living ability of elderly patients with acute cerebral infarction,which is worthy of promotion. 2018 Vol. 25 (28): 194-196 [Abstract] ( 174 ) HTML (35 KB)  PDF  (0 KB)  ( 28 ) 197 Intervention effect of meticulous nursing on 311 excimer laser in treatment of children with vitiligo YAO Han-fen;FENG Fan;HUANG Xiao-zhong Objective To explore the effect of meticulous nursing intervention on children with vitiligo treated by 311 excimer laser.Methods A total of 90 cases of vitiligo with 311 excimer laser admitted from March 2016 to March 2018 in our hospital were divided into the control group(n=44)and the observation group (n=46)according to the random number table method,the control group was treated with routine nursing and the observation group was treated meticulous nursing.The treatment effect of 311 excimer laser for vitiligo,bad emotional change and incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 93.5%,which was significantly higher than 77.3%of the control group,the difference was statistically significant(P<0.05）.After treatment,the SDS score(self-rating depression scale)and SAS score(self-rating anxiety scale)of the children in the observation group were significantly lower than that of the control group,the differences were statistically significant(P<0.05）.The total incidence of adverse reaction in the observation group was 2.2%,which was significantly lower than 15.9%of the control group,the difference was statistically significant(P<0.05）.Conclusion Meticulous nursing intervention can effectively improve the effect of 311 excimer laser treatment,improve the bad mood and reduce the incidence of adverse reaction. 2018 Vol. 25 (28): 197-199 [Abstract] ( 114 ) HTML (35 KB)  PDF  (0 KB)  ( 35 ) 200 Effect of the nursing management mode of information-motivation-behavioral skills model on the compliance behavior and quality of life in the patients with limb dysfunction after stroke ZHANG Xiao-xia;WANG Wen-fang Objective To observe the effects of the nursing management mode of information-motivation-behavioral skills (IMB)model on the compliance behavior and quality of life in the patients with limb dysfunction after stroke.Methods A total of 120 stroke patients who were admitted to our hospital from July 2016 to July 2017 were selected as the study subjects.According to the random number table method,they were divided into control group and study group,60 casec in each group.The control group was given conventional rehabilitation nursing intervention.The study group was given IMB nursing management model on the basis of the control group.The treatment compliance,daily living ability,muscle strength and quality of life were observed between two groups.Results After intervention,the treatment compliance,daily living ability and quality of life scores in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05）.After intervention,the muscle strength of the affected limb in the study group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05）.Conclusion The IMB nursing management model intervention can be applied in the patients with limb dysfunction after stroke,which can effectively improve the recovery of patients′limb function,improve treatment enthusiasm,improve self-care ability in daily life and quality of life,and promote patient recovery. 2018 Vol. 25 (28): 200-202 [Abstract] ( 117 ) HTML (34 KB)  PDF  (0 KB)  ( 31 ) 203 Application effect of personalized nursing intervention in the nursing of elderly patients with coronary heart disease WANG Fu-rong Objective To study the clinical application of personalized nursing intervention in the nursing of elderly patients with coronary heart disease.Methods60 elderly patients with coronary heart disease who were admitted to our hospital from January 2015 to January 2017 were selected as the study subjects.They randomly were divided into the control group and the experimental group,30 cases in each group.The control group was given regular nursing care,and on the basis of this,the experimental group was given personalized care.The nursing effect,quality of life score,incidence rate of adverse reactions,and incidence rate of complications were compared between the two groups.Results The nursing effect in the experimental group was significantly better than that in the control group (P<0.05）.The quality of life score was significantly higher than that in the control group(P<0.05）.The total incidence rate of adverse reactions and the total incidence rate of complications were significantly lower than those in the control group,the differences were statistically significant(P<0.05）.Conclusion Compared with the conventional nursing,individualized nursing intervention for elderly patients with coronary heart disease can improve the nursing efficiency and quality of life scores,reduce the incidence rate of adverse reactions and the incidence rate of complications,improve the selfcare ability and quality of life for patients,helps patients better recover their health and is helpful for future clinical medicine,so it is worthy of promotion. 2018 Vol. 25 (28): 203-205 [Abstract] ( 149 ) HTML (35 KB)  PDF  (0 KB)  ( 25 ) 206 Application effect of high quality nursing in children with febrile convulsion CHEN Zao-feng Objective To compare the effect of high quality nursing and routine nursing in children with febrile convulsion.Methods 80 children with febrile seizures in our hospital from February 2017 to February 2018 were selected and divided into the observation group and the control group according to the random number table method,40 cases in each group.The control group was received routine nursing care,and the observation group was received high quality nursing intervention on the basis of routine nursing of febrile convulsion.The frequency of relapse,the time of convulsion,incidence of complications,the satisfaction of the family members and degree of the family′s knowledge of the related health were compared between the two groups.Results After nursing of the two groups,the recurrent frequency of febrile convulsion in the observation group was lesser than that of the control group(P<0.05）.The time of termination of convulsion was shorter than that of the control group(P<0.05）.The total incidence of complications was lower than that of the control group(P<0.05）.The total rate of family satisfaction and knowledge of related diseases were all higher than those in the control group,the differences were statistically significant(P<0.05）.Conclusion High quality nursing can reduce the frequency of convulsion recurrence,shorten the termination time of convulsion,reduce incidence of complications,enhance the satisfaction of the family to nursing and improve the degree of the family′s knowledge of related diseases. 2018 Vol. 25 (28): 206-208 [Abstract] ( 125 ) HTML (34 KB)  PDF  (0 KB)  ( 34 ) 209 Intervention effect of standardized health education on peripherally inserted central catheter in patients with malignant lymphoma XIA Yan-ling;LIU Feng-hua;ZENG Sha;YI Jia;SUN Shu-yan;LI Li Objective To evaluate the effect of standardized health education on peripherally inserted central catheter(PICC)catheterization in patients with lymphoma during intercritical period.Methods From April 2015 to July 2017,82 patients with lymphoma who underwent PICC were enrolled in the study.They were equally divided into study group and reference group by random number table method.In the reference group,routine nursing was used,while in the study group,on the basis of routine nursing,standardized health education was adopted.The efficacy of different nursing interventions was compared and observed.Results Four weeks after discharge,the health responsibility score,physical activity score,nutritution score,mental health score,stress adjustment score,and interpersonal relationship score were (27.12±6.28)points,(22.20±5.22)points,(25.32±5.17)points,(26.24±4.32)points,(25.20±3.22)points,and(26.32±4.18)points in the study group,significantly higher than those in the reference group,(16.18±6.11)points,(15.19±4.27)points,(18.00±5.13)points,(19.28±5.14)points,(16.19±3.17)points and(16.00±4.13)points with statistical differences(P<0.05）.The total nursing satisfaction from patients in the study group was 90.24%,much higher than that of the reference group accounting for 70.73%with a significant difference (P<0.05）.The incidence of complications in the study group was 7.32%,greatly lower than that of the reference group accounting for 26.83%with statistical significance (P<0.05）.Conclusion Standardized health education for patients with lymphoma treated with PICC catheterization can reduce the patient′s complications,increase the nursing satisfaction,and effectively improve the patient′s healthy behavior. 2018 Vol. 25 (28): 209-211转215 [Abstract] ( 114 ) HTML (37 KB)  PDF  (0 KB)  ( 16 ) 212 Effect of comprehensive nursing intervention on postoperative gastrointestinal function and quality of life in patients with gastric cancer FANG Jia Objective To evaluate the effects of comprehensive nursing intervention on postoperative gastrointestinal function and quality of life in patients with gastric cancer.Methods From June 2016 to May 2017,eighty-eight patients with gastric cancer who underwent surgical treatment in our hoapital were selected.They randomly divided into control groups and observation group,44 cases in each group.In the control group was performed with symptomatic nursing,while the observation group,comprehensive nursing intervention was adopted.The influence of different nursing on postoperative gastrointestinal function and quality of life was evaluated.Results The recovery of bowel sounds,postoperative anal exhaust and recovery of bowel movement in the observation group were shorter than those in the control group(P<0.05）.There was no significant difference in the incidence of abdominal distension,mild abdominal distension or moderate abdominal distension in the two groups (P<0.05）.However,the incidence of severe abdominal distension in the observation group was lower,the score of each dimension of life quality were higher than those in the control group(P<0.05）,anxiety score were lower than those in the control group(P<0.05）.The anxiety scores of the two groups after the nursing were lower than those before the nursing with statistical significance (P<0.05）.Conclusion The implementation of comprehensive nursing interventions in patients with gastric cancer is effective. 2018 Vol. 25 (28): 212-215 [Abstract] ( 113 ) HTML (38 KB)  PDF  (0 KB)  ( 25 ) 216 Application effect of rapid rehabilitation surgical nursing in laparoscopic cholecystectomy ZOU Lian-di Objective To explore the application effect of rapid rehabilitation surgical nursing in laparoscopic cholecystectomy.Methods A total of 106 patients undergoing laparoscopic cholecystectomy from December 2015 to September 2017 in our hospital were selected as study subjects.They were equally divided in control group and observation group by lottery.In the control group,routine nursing was used during nursing,while in the observation group,rapid rehabilitation surgical nursing was adopted.The gas exhaust time,defecation time,hospital stay,and postoperative satisfaction were compared between the two groups.Results Compared with the control group，the gas exhaust time,defecation time and hospital stay were all shorter in the observation group(P<0.05）.The postoperative satisfaction score of the observation group was higher than that of the control group with statistical significance (P<0.05）.Conclusion In clinical practice,rapid rehabilitation surgical nursing for patients undergoing laparoscopic cholecystectomy obtains definite effects on shortening the time of gas exhaust,defecation and hospitalization,and improvement of postoperative satisfaction,thereby promoting the recovery of patient′s disease,which fully proves the feasibility of applying rapid rehabilitation surgical nursing. 2018 Vol. 25 (28): 216-218 [Abstract] ( 106 ) HTML (31 KB)  PDF  (0 KB)  ( 27 ) 219 Contrast the effect of systematic risk management and traditional model of nursing in pediatric intravenous infusion ZHANG Shao-hong Objective To investigate and contrast the effect of systematic risk management and traditional model of nursing in pediatric intravenous infusion.Methods Sixty child patients treated in our hospital from January 2015 to January 2018 were retrospectively analyzed.According to difference nursing methods,they were divided into control group(30 cases)and observation group(30 cases).In the control group,patients were adopted the traditional model of nursing.In the observation group,patients were adopted the systematic risk management on the base of conventional nursing.The incidence of adverse events and risk events and satisfaction of nursing were statistically analyzed between two groups.Results The incidence of risk events in the observation group was lower than that control group,and the difference was statistically significant(P＜0.05）.The incidence of adverse events in the observation group was lower than that control group,and the difference was statistically significant(P＜0.05）.The total satisfaction of the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05）.Conclusion The incidence of adverse events and risk events can be effectively reduced by adopting the systematic risk management in pediatric intravenous infusion.At the same time,it significantly improve the family′s satisfaction with the nursing process.and is worthy of clinical recommendation. 2018 Vol. 25 (28): 219-封三 [Abstract] ( 124 ) HTML (33 KB)  PDF  (0 KB)  ( 32 )

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