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Quick Search     Adv Search 2016 Vol. 23, No. 36 Published: 2016-12-28   4 The establishment and evaluation of a model of stretch-induced mechanical injury on cultured oligodendrocyte precursor cells from neonatal rat spinal cord in vitro MA Xiang;QI Yue-hong;WEI Jian-feng;LI Yan-ze;BI Jing;LYU Lei;GUO Yong-qing ObjectiveTo establish a model of stretch-induced mechanical injury on cultured oligodendrocyte precursor cells(OPCs)in vitro with the FX-4000TTMsystem,in order to further explore the role and mechanism of OPCs in spinal cord injury and repair.MethodsOPCs were separated from spinal cord of neonatal rats and then purified with the shaking method in vitro.Immunofluorescence assay was applied to identify the separated cells.A FX-4000TMsystem was used to apply cyclic stretch.The purified OPCs were randomly divided into four groups∶group A (control group),group B (5%tensile strain),group C (10%tensile strain),group D(15%tensile strain).After OPCs were strained for 2 h by the FX-4000TTMsystem,morphology of OPCs was observed by using inverted microscope,viability of OPCs was measured by MTT assay and apoptosis of the cells was detected by double staining flow cytometry,damage models were evaluated.ResultsThe percentage of purified OPCs in vitro was more than 90%.There were no significant differences between group A and group B in survival rate and cell morphology.Compared with group A,survival rate of OPCs in group C and D was significantly decreased(P＜0.05),apoptosis rate of OPCs was significantly increased(P＜0.05),and obvious pathological morphologic changes of OPCs were also observed in group C and D.However,there was a large loss of cell attachment and survival rate of OPCs was found to be less than 50%in group D.ConclusionThe model of stretch-induced mechanical injury on cultured OPCs can be established by applying 10%tensile strain with the FX-4000TTMsystem. 2016 Vol. 23 (36): 4-7 [Abstract] ( 149 ) HTML (51 KB)  PDF  (0 KB)  ( 30 ) 8 Influence study of Jiawei Wupi Decoction on E2,VEGF and CFTR of ovarian hyperstimulation syndrome model rats CHEN Jin;CHEN Xiao-yong;HU Li-sha;WU Xiao-hua;CHEN Ling-yan;XU Zhong-bo;FANG Fang ObjectiveTo explore the influence of Jiawei Wupi Decoction on E2,VEGF and CFTR in rats with ovarian hyperstimulation syndrome (OHSS).Methods30 female Wistar rats(SPF grade)were randomly divided into the model traditional Chinese medicine group and the model control group,15 cases in each group.PMSG+HCG way were used on the rats of two groups to establish OHSS model,at the same time,Jiawei Wupi Decoction and normal saline were given. After 48 h of HCG injection,the abdominal cavity was cut along the midline of abdomen and the ovaries were weighed. The expression of VEGF and CFTR protein in the ovary of rats were detected by immunohistochemistry.Neutral serum E2level was detected by RIA.ResultsThe expression of VEGF protein,CFTR protein and serum E2in model traditional Chinese medicine group were (62.20±11.71),(57.20±19.82),(26.91±7.63)pg/ml，the model control group were (136.31± 22.74),(111.32±32.25),(32.55±6.63)pg/ml，the difference was statistically significant(F=69.097,P=0.01;F=67.057,P=0.01; F=16.36,P=0.01).ConclusionJiawei Wupi Decoction can effectively decrease the level of E2in OHSS rats and the expression of VEGF and CFTR protein in ovarian tissues of OHSS rats. 2016 Vol. 23 (36): 8-10转14 [Abstract] ( 146 ) HTML (48 KB)  PDF  (0 KB)  ( 25 ) 11 Clinical and pathological observation on the rosette-forming glioneuronal tumor of the fourth ventricle LI Yun-yuan;LI Wei-qing;MA Xiao-mei;XU Rong-rong;XIA Chun-yan ObjectiveTo explore clinical pathological characteristics,imaging changes and differential diagnosis of rosette-forming glioneuronal tumor (RGNT)in the fourth ventricle for improving the understanding of the disease.MethodsThe clinical,radiological,and pathological features of the three patients with RGNT in our hospital from November 2007 to July 2015 were analyzed retrospectively,and the relevant literature were reviewed.ResultsAll the patients were male with a mean age of 19 years(from 14 to 26).The clinical symptoms included dizziness,vomiting,ataxia and so on.MRI revealed hypo-intensity on T1-weighted image,hyper-intensity on T2-weighted image.Histopathological findings showed the typical biphasic feature with neurocytic and glial architecture.The neoplastic tissue consisted of small cells with round nuclei resembling neurocytes often arranged to form neurocytic rosettes or perivascular rosettes radiating around central capillaries.The glial component tended to exhibit pilocytic astrocytoma like morphology with long,hair-like processes.ConclusionRGNT in the fourth ventricle is a rare and slow growth neoplasm.The tumor often occur in the fourth ventricle,with its unique histological,immunohistochemical features.Current management has relied on surgery,and postoperative long-term close follow-up is needed. 2016 Vol. 23 (36): 11-14 [Abstract] ( 149 ) HTML (48 KB)  PDF  (0 KB)  ( 23 ) 15 Progress of surgical treatment for thyroid papillary carcinoma LIANG Bei Thyroid papillary carcinoma is one of the most common malignant tumors in endocrine system.In recent years,with the change of environment,there has been an upward trend in the incidence rate of thyroid papillary carcinoma globally.Meanwhile,with the development of ultrasonic medicine,the accuracy of the early diagnosis for thyroid papillary carcinoma has rised,providing a more favorable opportunity for surgery.Surgery is still the main treatment for thyroid papillary carcinoma,but there are certain differences at home and abroad.Although the traditional surgery is still the mainstream of the treatment for such diseases,new surgical procedures like percutaneous ablation under ultrasound guidance has begun to draw more attention and provide new idea for treating thyroid papillary carcinoma.This article reviewed for the progress of thyroid papillary carcinoma surgical treatment. 2016 Vol. 23 (36): 15-17 [Abstract] ( 159 ) HTML (38 KB)  PDF  (0 KB)  ( 33 ) 18 Research progress of cervical intervertebral fusion cage LI Sheng-can;LIN Fei-yue Anterior cervical discectomy and fusion（ACDF）is the standard surgical technique for cervical disease.There are many complications while using plate combined cage such as plate or screw displacement,dysphagia,adjacent segment degeneration.The anchored cage has the advantages of good stability,high fusion rate,easy to use,meanwhile,with less dysphagia and adjacent segment degeneration happen.So this paper reviewed recent literatures about the cervical anchored cages. 2016 Vol. 23 (36): 18-20转38 [Abstract] ( 196 ) HTML (43 KB)  PDF  (0 KB)  ( 34 ) 21 Clinical effect of percutaneous catheter intervention in the treatment of spinal tuberculosis complicated with abscess WU Yu-qing;CAI Long-ren;HU Yan-hong ObjectiveTo study the clinical value of percutaneous catheter intervention in the treatment of spinal tuberculosis complicated with abscess.Methods60 cases of spinal tuberculosis complicated with abscess in our hospital from January to December 2013 were randomly divided into control group and observation group,30 cases in each group.Patients in the control group were given conventional open debridement treatment,and chemotherapy for 18 months;patients in the observation group were given with CT guided percutaneous puncture tube interventional treatment,retention of drainage tube,using Isoniazid and Rifampin combined with Amikacin local treatment for 4 weeks,and systemic chemotherapy for 18 months(program with the control group).After the course of treatment,patients were followed up for 1-2 years.Cure rate,recurrence rate,incidence rate of complications and change of JOA score between two groups were compared.ResultsThere was significant difference in the cure rate between two groups (P＜0.05),and recurrence rate was significantly lower than that of the control group (P＜0.01);incidence rate of complications in the observation group was significantly lower than that in the control group (P＜0.05).After treatment,thoracic and lumbar JOA score of two groups were significantly improved(P＜0.05);thoracic JOA score and lumbar JOA score of in the observation group after treatment were significantly higher than those in the control group(P＜0.05).ConclusionCT guided penetrating puncture catheter intervention in the treatment of spinal tuberculosis complicated with abscess has better results,fewer postoperative recurrence,fewer complications,and good clinical application value. 2016 Vol. 23 (36): 21-23 [Abstract] ( 141 ) HTML (42 KB)  PDF  (0 KB)  ( 35 ) 24 Study of erythrocytosis in the diagnosis of diabetes mellitus complicated with sleep apnea hypopnea syndrome ZHONG Yi-hua;WEN Yue-xiu;FU Yan-ling ObjectiveTo investigate the role of increased red blood cells(RBC)in the diagnosis of type 2 diabetes mellitus(T2DM)complicated with obstructive sleep apnea hypopnea syndrome(OSAHS).MethodsBy a perspective view, 40 patients with T2DM diagnosed in our hospital from January to December 2015 were randomly selected.20 patients with RBC increased were classified into experimental group,and the rest of 20 patients with normal RBC was categorized into control group.Incidence rate of OSAHS,physiological index and severity of OSAHS in T2DM patients were evaluated.ResultsIncidence rate of OSAHS in the experimental group was 90%,higher than 30%in the control group (P＜0.05).There was significant difference in the physiological indexes of OSAHS between two groups(χ2=15.00,P＜0.01).ConclusionRBC examination in T2DM patients is beneficial to early detection and treatment of OSAHS,can control patients′condition as early as possible and reduce incidence of cardiovascular and cerebrovascular diseases. 2016 Vol. 23 (36): 24-26 [Abstract] ( 144 ) HTML (40 KB)  PDF  (0 KB)  ( 28 ) 27 Clinical application value of fiber bronchoscopy in ICU complicated with pulmonary infection MO Jun-de;LIN Ping;ZHANG Ri-lin;CHEN Lian-fang;ZHONG Guo-rong ObjectiveTo investigate the clinical value of bronchoscopy in intensive care unit(ICU)complicated with pulmonary infection.Methods96 cases of ICU patients complicated with pulmonary infection in our hospital from February 2014 to July 2016 were randomly divided into control group and observation group,48 cases in each group.Patients in the control group was given routine pulmonary anti infection treatment,while patients in the observation group received bronchoalveolar lavage and sputum aspiration treatment,clinical curative effect and serum inflammatory stress index and arterial blood gas changes before and after treatment in two groups were compared.Results Compared with control group,cough disappearance time,pulmonary rales disappeared time in the observation group was significantly shortened,and the difference was statistically significant(P＜0.05);clinical curative effect of observation group total effective rate(95.83%)was significantly higher than that of the control group(83.33%),and the difference was statistically significant(P＜0.05);for the treatment of 24,72 h compared with the control group,the changes of PCT,hs-CRP in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P＜0.05).PaO2and SaO2,FaO2/FiO2in the observation group was significantly higher than that in the control group,level of PaCO2was significantly lower than that in the control group,and the differences were statistically significant(P＜0.05).ConclusionBronchoalveolar lavage and sputum aspiration in the treatment of ICU complicated with pulmonary infection can effectively improve clinical efficacy,improve respiratory status and inflammatory stress levels in patients with severe pulmonary infection,it is worthy of clinical application. 2016 Vol. 23 (36): 27-29 [Abstract] ( 141 ) HTML (37 KB)  PDF  (0 KB)  ( 34 ) 30 Effect of nerve block in the prevention of pulmonary infection after hepatobiliary and pancreatic surgery ZHANG Bin ObjectiveTo study effect of nerve blocking in the prevention of pulmonary infection after hepatobiliary and pancreatic surgery.Methods92 patients treated in our Department of Hepatobiliary and Pancreatic Surgery from February 2014 to February 2016 were divided into study group and control group according to preoprerative intercostal nerve block,46 cases in each group.Patients in the study group were given intercostal nerve block before cutting skin,patients in the control group were injected muscle Flurbiprofen 50 mg when they felt painful.Postoperative respiratory function index (R,SpO2,V,FEV1）,postoperative analgesia effect score and incidence rate of postoperative pulmonary infection between two groups were compared.ResultsThere was no significant difference of value of R,SpO2,V,FEV1before and after surgery in the study group (P＞0.05),while in the control group,R value after surgery was higher than that before surgery,and value of SpO2、V、FEV1after surgery was lower than that before surgery,and the difference was statistically significant(P＜0.05).And analgesia effect score in the study group was significantly better than that in the control group (P＜0.01).Incidence rate of postoperative pulmonary infection in the study group(6.52%)was also significantly lower than that in the control group(26.09%)(χ2=6.45,P＜0.05).ConclusionNerve block in the patient underwent hepatobiliary and pancreatic surgery can relieve pain,prevent respiratory function weakening and reduce incidence of postoperative pulmonary infection effectively,therefore promote patients′recovery. 2016 Vol. 23 (36): 30-32 [Abstract] ( 139 ) HTML (43 KB)  PDF  (0 KB)  ( 32 ) 33 Effect analysis of complete laparoscopic splenectomy combined with pericardial devascularization in the treatment of cirrhosis portal hypertension DENG Xiao-hong;ZHOU Lin XIAO;Xiu-lin XIE;Yuan-cai ObjectiveTo evaluate clinical efficacy of complete laparoscopic splenectomy combined with pericardial devascularization in the treatment of cirrhotic portal hypertension.Methods66 patients with cirrhotic portal hypertension combined with upper gastrointestinal bleeding who were diagnosed and admitted into our hospital from October 2011 to September 2015 were selected as research subjects and divided into observation group (n=32)and control group(n=34)according to different therapeutic methods.Patients in the control group were given were given conventional splenectomy combined with pericardial devascularization,while patients in the observation group were treated with complete laparoscopic splenectomy combined with pericardial devascularization.Clinical curative effects between two groups were compared.ResultsThere were no significant differences between two groups in the intraoperative blood loss,postoperative drainage volume,total hospitalization cost and postoperative complication rate (P＞0.05);postoperative anal exhaust time and postoperative hospital stay in the observation group was significantly shorter than that in the control group(P＜0.05);operation time of the observation group was significantly longer than that of the control group,and the difference was statistically significant(P＜0.01).There were significant differences in incision length,fasting time and postoperative analgesia times between two groups(P＜0.05).Conclusion Complete laparoscopic splenectomy combined with pericardial devascularization in the treatment of cirrhosis portal hypertension is a safe and feasible surgical procedure. 2016 Vol. 23 (36): 33-35转41 [Abstract] ( 157 ) HTML (41 KB)  PDF  (0 KB)  ( 41 ) 36 Application effect of cortical electrode EEG monitoring in glioma induced by epilepsy operation HU Shan ObjectiveTo investigate the application effect of cortical electrode EEG monitoring in glioma induced by epilepsy operation.Methods60 patients with glioma induced by epilepsy treated by our hospital from February 2013 to February 2016 were selected and they were divided into the observation group(n=30)and control group(n=30).In the observation group,CT applied to determine the location of lesions while using cortical electrode EEG monitoring to resect tumor,while in the control group CT applied simply to determine the location of lesions to resect tumor,and all patients were followed up for investigation of epilepsy attack to record in detail the change of disease in the two groups,and the result was analyzed statistically.ResultsThe total resection,near total resection and most resection of the tumor in the observation group was 60.00%,30.00%,10.00%respectively,and it was 20.00%,26.67%,53.33%respectively in the control group,and the difference between the two groups was statistically significant(P＜0.05).Within 1 years after treatment, Engel classification in the observation group∶7 cases for gradeⅠ,14 cases for gradeⅡ,8 cases for gradeⅢ,1 case for grad Ⅳ,and it was 2,6,2,20 cases in the control group were,and the difference of Engel grade was statistically significant between two group (P＜0.05).ConclusionCortical electrode EEG monitoring has a very high application value for significantly determine the epileptogenic lesion,accurate resection of lesion during surgery,improving the effect of surgical treatment and improving the prognosis,reducing the symptoms of patients,and reducing the postoperative recurrence rate. 2016 Vol. 23 (36): 36-38 [Abstract] ( 157 ) HTML (37 KB)  PDF  (0 KB)  ( 41 ) 39 Clinical effect of Argatroban combined with Edaravone in the treatment of atrial fibrillation complicated with cerebral embolism HUANG Chun;ZHU Fei;HU Xi-hui ObjectiveTo explore the clinical efficacy of Argatroban combined with Edaravone in the treatment of atrial fibrillation complicated with cerebral embolism.Methods76 patients with atrial fibrillation and cerebral embolism admitted into our hospital from March 2014 to May 2016 were selected.Based on dynamic random classification,they were divided into research group (n=38)and control group (n=38).The patients in the control group were treated with Low Molecular Weight Heparin and the patients in the research group were treated with Argatroban combined with Edaravone.The score of national institutes of health stroke scale （NIHSS),Barthel score of activities of daily living,and coagulation indicator between two groups were compared.ResultsThere was no statistical difference in NIHSS score or Barthel score between two groups before treatment(P＞0.05).After therapy,the score of NIHSS was(9.15±2.12)points, and Barthel score was（76.57±14.23)points,which caught great superiority in comparison with those in the control group [(15.47±4.35)points,(58.45±12.31)points](P＜0.05).No great difference was displayed in the coagulation indicator before treatment(P＞0.05),but after therapy,the advantage was greater in the research group compared with that in the control group (P＜0.05).ConclusionArgatroban combined with Edaravone in the treatment of atrial fibrillation complicated with cerebral embolism can effectively improve neurologic impairment,ability of daily life activities,as well as coagulation indicator,which is worthy of widespread promotion in clinic. 2016 Vol. 23 (36): 39-41 [Abstract] ( 169 ) HTML (37 KB)  PDF  (0 KB)  ( 31 ) 42 Clinical analysis of epileptic seizures after skull defect cranioplasty ZHANG Bai-lin;ZHANG Zhen-yu;LI Wei;HUANG Qian-liang;YE Xin-yun ObjectiveTo explore the cause and control measures of epileptic seizure after craniocerebral defect surgery.MethodsFrom December 2012 to June 2016,the clinical data of 130 patients undergone craniofacial defect surgery in the department of neurosurgery,in our hospital were retrospectively analyzed in order to find the postoperative cause and therapeutic measures of epileptic seizure.According to whether antiepileptic drug used or not,they were divided into prevention epilepsy group(n=72)and non-prevention epilepsy group(n=58).The incidence of epileptic seizure in two groups were compared.ResultsAmong 130 cases,16 patients(12.3%)were occurred with epileptic seizure,focal seizures in 11 and generalized seizures in 5.After surgery,the occurred situation with epileptic seizures in the prevention epilepsy group, displayed a statistical difference compared with that in the non-prevention epilepsy group (P＜0.05).ConclusionPreoperative epileptogenic foci,postoperative cerebral hemodynamic changes,intraoperative brain injury,and dural rupture are the possible causes of epileptic seizures after craniofacial defect surgery.Intraoperative normative operation and postoperative prophylactic drug use can decrease the occurrence of epileptic seizure after surgery. 2016 Vol. 23 (36): 42-44 [Abstract] ( 138 ) HTML (36 KB)  PDF  (0 KB)  ( 38 ) 45 Effect of Atorvastatin Calcium on carotid atherosclerotic plaque and hs-CRP and blood lipid levels in patients with acute cerebral infarction HUANG Bi-wu;GUO Yun-shi;WANG Zi-yuan ObjectiveTo explore the effect of Atorvastatin Calcium on carotid atherosclerotic plaque and High sensitive C reactive protein(hs-CRP)in patients with acute cerebral infarction.Methods60 cases of patients with acute cerebral infarction and carotid plaque from July 2014 to January 2016 were selected and randomly divided into two groups,30 cases in the control group were given Rosuvastatin Calcium for treatment,30 cases in observation group were given A-torvastatin Calcium for treatment,the treatment effect was compared between two groups,and the serum levels of hs-CRP and blood lipid levels before and after treatment were compared between two groups.ResultsAfter 6 months of treatment,the effective rate in the observation group was 93.33%,which was significantly higher than that of control group of 73.33% (P＜0.05);the serum hs-CRP concentration,total cholesterol,triglyceride and low density lipoprotein cholesterol were significantly lower in the observation group after treatment,and lower than those of control group after treatment(P＜0.01).ConclusionAtorvastatin Calcium can effectively reduce the acute cerebral infarction with carotid atherosclerosis in patients with hs-CRP and blood lipid levels has significant curative effect on carotid artery plaque, which is worthy of clinical application. 2016 Vol. 23 (36): 45-47 [Abstract] ( 138 ) HTML (35 KB)  PDF  (0 KB)  ( 24 ) 48 Relationship of prostate biopsy positive results and preoperative examination in prostate specific antigen gray area patients WANG Mei-cai;ZHOU Rong-sheng;ZHOU Xiang-ju;PANG Kun;HAN Cong-hui ObjectiveTo investigate correlation of prostate biopsy positive results and preoperative examination in prostate specific antigen (PSA)Gray area patients.Methods495 patients who underwent prostatic biopsy in the PSA gray area from March 2011 to March 2016 in Department of Urology of Central Hospital of Shuyang County and Xuzhou City Central Hospital were retrospectively studied and divided into two groups of prostatic biopsy positive group(n=150) and prostatic biopsy negative group (n=345)according to the results of prostatic biopsy.Age,smoking or not,whether hypertension,whether diabetes,MRI nodules,digital rectal examination (DRE)nodules,PSA,free PSA (FPSA),PSA density (PSAD),prostate volume between two groups were compared,and correlation of puncture positive result and preoperative examination was analyzed.ResultsThere were no significant differences between two groups in age,smoking or not, whether hypertension,whether diabetes,and FPSA,prostate volume between two groups(P=0.1078,0.6375,0.0517,0.4811, 0.1363,0.2915;all P＞0.05);There were statistically significant difference in MRI nodules,DRE nodules,PSA,PSAD(all P＜0.01).Pearson correlation analysis results showed that MRI nodules,DRE nodules,PSA,PSAD had positive correlation with transrectal prostate biopsy positive (r=0.236,0.536,0.331,0.536;all P＜0.05).Conclusion Positive rate of puncture is higher in patients of PSA gray area with higher PSA,higher PASD,MRI or DRE found nodules;age,smoking,hypertension,diabetes,FPSA have no relationship with puncture result. 2016 Vol. 23 (36): 48-50 [Abstract] ( 136 ) HTML (37 KB)  PDF  (0 KB)  ( 33 ) 51 Related factor of urinary sepsis after percutaneous nephrolithotomy DENG Yue-yun;LI Xiu-ning ObjectiveTo explore related factor of urinary sepsis after percutaneous nephrolithotomy(PCNL).Methods45 patients who conducted PCNL in People′s Hospital of Yunfu City from March 2013 to April 2016 were collected. Postoperative urinary sepsis in 28 cases,factors of age,sex,urine white blood cell,blood white blood cells,preoperative urine culture,renal function,renal stone size,renal effusion,surgery history,bleeding volume and operation time were group compared,and Logistic regression analysis was performed on the factors which were statistically different to get related factors of urinary sepsis after PCNL.ResultsComparison different groups of urine white blood cell,preoperative urine culture,renal function,renal stone size,renal effusion,surgery history,intraoperative bleeding volume and operation time,the difference was statistically significant(P＜0.05).Logistic regression analysis found that urine culture,renal function,renal stone size,operation history and operation time were related to urinary sepsis after PCNL.ConclusionAim at processing and evaluation the factors of positive urine culture,renal injury,larger renal stones,surgery history of urinary tract,ecaluation of longer operation time before operation are expected to prevent and reduce occurrence rate of urinary sepsis after PCNL. 2016 Vol. 23 (36): 51-53 [Abstract] ( 130 ) HTML (36 KB)  PDF  (0 KB)  ( 37 ) 54 Clinical study of acupotomy lysis treating mild to moderate carpal tunnel syndrome CHEN Jin-hui;ZHU Jun-teng;XU Jian-ping ObjectiveTo investigate the clinical effect of acupotomy lysis treating mild to moderate carpal tunnel syndrome.Methods94 patients with mild to moderate carpal tunnel syndrome treated in our hospital from July 2014 to December 2015 were selected as study subjects.They were randomly divided into observation group (n=47)and control group (n=47).The control group was treated with acupuncture and moxibustion，the observation group were treated with acupotome lysis therapy.After 2 weeks treatment,the clinical efficacy between two groups was compared.ResultsThe total effective rate of the observation group (95.74%)was significantly higher than the control group (85.11%),and the difference was statistically significant(P＜0.05).After treatment,Levine carpal tunnel syndrome questionnaire score in two groups were significantly lower than before treatment,and the observation group was significantly better than the control group after treatment,and the difference was statistically significant (P＜0.05).ConclusionAcupotomy lysis treating mild to moderate carpal tunnel syndrome is helpful to improve the clinical symptoms,the curative effect is remarkable,and it can be popularized in clinic. 2016 Vol. 23 (36): 54-56 [Abstract] ( 174 ) HTML (39 KB)  PDF  (0 KB)  ( 38 ) 57 Effect comparison of absorbable screw internal fixation and traditional internal fixation in the treatment of intra-articular fractureof extremities LIUJia-kai ObjectiveTo compare the effect of absorbable screw internal fixation and traditional internal fixation in the treatment of intra-articular fracture of extremities.Methods132 cases with intra-articular fracture of extremities treated in department of orthopedics of our hospital from March 2015 to March 2016 were selected and they were divided into the experimental group and control group,and there were 66 cases in each group.The experimental group was treated with absorbable screw fixation,while the control group was treated with traditional internal fixation.The effective rate and incidence rate of complication between two groups were compared.ResultsThe effective rate was 92.42%,and the control group was 65.15%,and there was a statistical difference between two groups(P＜0.05).The incidence rate of complication of the experimental group was significantly lower than that of the control group (P＜0.05).ConclusionThe effect of absorbable screw internal fixation and traditional internal fixation in the treatment of intra-articular fracture of extremitiesis better,and it can improve the treatment prognosis of patients.It has more clinical security.The treatment deserves to be promoted. 2016 Vol. 23 (36): 57-59 [Abstract] ( 160 ) HTML (38 KB)  PDF  (0 KB)  ( 39 ) 60 Effect observation of CO2laser in the treatment of early glottic cancer WU Shi-an;PENG Feng;CHEN Zhen-qing;WU Mei-ling ObjectiveTo explore the effect of CO2laser in the treatment of early glottic cancer.Methods40 patients with early glottic cancer from May 2007 to May 2015 in our hospital were selected and divided into the observation group and the control group according to random number table method,and 20 cases in each group.The control group was given routine surgery,and the observation group was treated with CO2laser.The operation time,length of hospital stay and the incidence rate of postoperative complications in the two groups were observed and the recurrence rate was recorded.ResultsThe operation time and length of hospital stay in the observation group was shorter than that in the control group,and the amount of bleeding in the observation group was less than that in the control group,with significant difference (P＜0.01).The incidence rate of postoperative complications in the observation group was 5.00%,which was lower than 45.00%in the control group,with significant difference(P＜0.05).The survival rate at the second and the third years of the observation group was higher than that of the control group,with significant difference(P＜0.05).ConclusionThe effect of CO2laser in the treatment of early glottic cancer is significant,which has the advantages of less trauma,less complications,fast recovery and high survival rate,and it is worthy of clinical promotion and application. 2016 Vol. 23 (36): 60-62 [Abstract] ( 148 ) HTML (38 KB)  PDF  (0 KB)  ( 39 ) 63 Clinical effect of low dose Thalidomide combined with VED chemotherapy in the treatment of elderly patients with newly diagnosed multiple myeloma LIN Zhi-juan;LUO Yi-ming ObjectiveTo explore the clinical effect of low dose Thalidomide combined with VED chemotherapy in the treatment of elderly patients with newly diagnosed multiple myeloma.Methods82 elderly patients with newly multiple myeloma in our hospital from July 2011 to June 2016 were selected and randomly divided into the experimental group and the control group,41 cases in each group.The control group was treated with standard VED regimen chemotherapy, the experimental group was treated with low-dose Thalidomide combined with standard dose chemotherapy of VED.The total effective rate,the incidence rate of adverse reaction,Karnofsky score after treatment,hemoglobin index,bone marrow plasma cell count,and serum M protein were compared between the two groups.ResultsThe total effective rate of the experimental group was 85.37%,which was higher than 63.41%of the control group,with significant difference(P＜0.05). The number of bone marrow plasma cells and serum M protein after treatment in the experimental group was lower than that in the control group,the Karnofsky score and hemoglobin after treatment in the experimental group was higher than that in the control group,with significant difference (P＜0.05).The incidence rate of constipation and mild sleepiness in the experimental group was higher than that in the control group,with significant difference (P＜0.05).There was no significant difference in the incidence rate of the rest adverse reactions between the two groups(P＞0.05).After treatment, the patient′s symptoms of mild sleepiness and constipation were significantly alleviated,which did not affect the treatment.ConclusionFor elderly patients with newly diagnosed multiple myeloma,the application of low dose Thalidomide combined with chemotherapy is safe and effective,were well tolerated,with good clinical feasibility,it is worthy of further promotion and application. 2016 Vol. 23 (36): 63-65转72 [Abstract] ( 152 ) HTML (41 KB)  PDF  (0 KB)  ( 37 ) 66 Application of transperineal two-dimensional and three-dimensional ultrasonography in the evaluation of the levator ani muscle deformation in postmenopausal women with pelvic floor dysfunction LAN Ying ObjectiveTo investigate the application value of transesophageal two-dimensional and three-dimensional ultrasonography in the evaluation of the levator ani muscle deformation in postmenopausal women with pelvic floor dysfunction.Methods64 cases of women with pelvic floor dysfunction were admitted to our hospital from August 2015 to October 2016.All patients were examined through two-dimensional and three-dimensional ultrasonography.32 cases of postmenopausal women with pelvic floor dysfunction were chosen as the observation group,and 32 cases of nonmenopausal female patients with pelvic floor dysfunction were chosen as the control group.A discussion was carried out on the application of transperineal two-dimensional and three-dimensional ultrasonography in the evaluation of the levator ani muscle deformation in postmenopausal women with pelvic floor dysfunction through assessing the pelvic floor prolapse and the levator ani hiatus deformation of the patients in the two groups.The distance of vesical neck downmoving,urethral rotation angles,the distance of pelvic bulging,uterine down-moving,rectal down-moving was observed; left-right diameter,anteroposterior,perimeter and area of anal levator hiatal at resting and Valsalva gesture was recorded.ResultsThere was no significant difference between the two groups in the distance of vesical neck down-moving(P＞0.05);the urethral rotation angle of patients in the observation group was larger than that in the control group(t=2.0608, P=0.0435);the distance of pelvic bulging in the observation group was longer than that in the control group (t=3.6267,P=0.0006);there were 24 cases of uterinedown-moving in the observation group,which was more than that in the control group(17 cases),the uterine down-moving distance in the observation group was longer than that in the control group (t=4.4759,P=0.0000);for the observation group,there were 23 cases with rectal down-moving,which was larger than the number of cases with rectal down-moving in the control group(15 cases);the rectal descent distance in the observation was longer than that in the control group (t=4.1457、4.7955,P=0.0417、0.0000).In the observation group,left-right diameter,anteroposterior,perimeter and area of anal levator hiatal were significantly greater than those of the patients in the control group whether at resting and Valsalva action,the differences between the two groups were statistically significant(P＜0.01).ConclusionTransperineal twodimensional and three-dimensional ultrasonography can reflect the degree of levator ani hiatus deformation of patients, provides effective reference for the evaluation of the levator ani muscle deformation in postmenopausal women with pelvic floor dysfunction. 2016 Vol. 23 (36): 66-68 [Abstract] ( 135 ) HTML (38 KB)  PDF  (0 KB)  ( 36 ) 69 Effect of Zhike Pingchuan Decoction on children with bronchial asthma and its influence on sub-group of T lymphocyte and serum of IL-4 and IFN-γ LIU Yuan-song ObjectiveTo explore the effect of Zhike Pingchuan Decoction on children with bronchial asthma and its influence on sub-group of T lymphocyte and serum of interferon-γ(IFN-γ)and interleukin-4(IL-4).MethodsA total of 82 children definitely diagnosed as bronchial asthma in our hospital from June 2012 to April 2016 were selected as research objects.They were randomly divided into control group(n=40)and observation group(n=42).In the control group, inhalant of Budesonide Formoterol Powder was used,while in the observation group,Zhike Pingchuan Decoction was added on the basis of the control group.The course of treatment was 3 months.The clinical effect in the two groups was compared.ResultsAfter 3-month therapy,frequency of asthma attack per month and frequency of upper respiratory infection (URI)were both less than those before treatment,the time of asthma after treatment was shorter,the IL-4 level was lower and the INF-γ level was higher in comparison with those before treatment,the differences were statistically significant(P＜0.05).In the observation group,frequencies of asthma attack per month and URI were less than those in the control group after 3-month therapy,symptom of asthma was shorter,the level of IL-4 was lower and level of INF-γ was higher than those in the control group after therapy,the differences were statistically significant(P＜0.05).In the control group,sub-group of T lymphocytes incuding CD3+,CD4+,and CD4+/CD8+was not greatly improved,while in the observation group,these indexes were significantly improved,the differences were statistically significant(P＜0.05).The total effective rate in the observation group was 92.86%,much higher than that in the control group(77.50%),the difference was statistically significant(P＜0.05).ConclusionApplication of Zhike Pingchuan Decoction is effective in treating bronchial asthma,which can improve the inflammatory response and immune function,and is worthy of promotion. 2016 Vol. 23 (36): 69-72 [Abstract] ( 153 ) HTML (47 KB)  PDF  (0 KB)  ( 36 ) 73 Effect observation of Budesonide Inhalation in the treatment of Mycoplasma pneumonia ZHAO Jing-ci;LIU Jing ObjectiveTo investigate the curative effect of nebulized Budesonide in the treatment of children with Mycoplasma pneumoniae pneumonia.Methods75 children with Mycoplasma pneumonia pneumonia in our hospital from August 2013 to May 2016 were selected and divided into the treatment group(n=40)and control group(n=35).The two groups were treated with the conventional treatment,and the treatment group was given the treatment of Azithromycin and Budesonide Atomization Inhalation in addition,while the control group was treated only by Azithromycin.After the treatment,the effect of the two groups was compared.ResultsIn the treatment group,the effective rate (97.5%)was significantly higher than that in the control group(82.9%).The time of body temperature returned to normal,wheeze disappeared,and moist rales disappeared,cough weire disappeared in the treatment group was shorter than that of the control group;the incidence of adverse reactions in the treatment group (5.0%)was significantly lower than that in the control group(20.0%);the differences between the two groups were statistically significant(P＜0.05).ConclusionBudesonide Inhalation in the treatment of Mycoplasma pneumonia has significant clinical effect.It has less adverse reaction,safe and effective,and is worth in clinical promotion. 2016 Vol. 23 (36): 73-75 [Abstract] ( 163 ) HTML (38 KB)  PDF  (0 KB)  ( 37 ) 76 Clinical analysis of the delivery modes and pregnancy outcomes of pregnant women with cicatricial uterus ZHOU Jian ObjectiveTo study the delivery modes and pregnancy outcomes of pregnant women with cicatricial uterus.Methods80 cases of pregnant women with cicatricial uterus treated in our hospital from March 2013 to March 2016 were selected as the research group.Simultaneously,80 cases without cicatricial uterus who had undergone cesarean section were selected as the control group.A comparative analysis was carried out between the two groups in delivery modes and pregnancy outcomes.ResultsOf the 80 patients with cicatricial uterus,71 cases underwent cesarean section, accounting for 88.75%,9 cases underwent vaginal delivery,accounted for 11.25%;of the 71 cases undergoing cesarean section,26 cases did not meet with the indications of vaginal delivery,accounted for 32.50%,45 cases received cesarean section out of the will of patients or their family members,accounting for 56.24%;of the 9 cases of vaginal delivery, 7 cases were successful,2 cases were transferred to cesarean section.The amount of bleeding in the research group was significantly more than that in the control group (P＜0.01),and their delivery time and hospitalization periods were significantly shorter than those of the control group (P＜0.01).There was no significant difference in Apgar scores between the two groups(P＞0.05).Patients in the research group had an obviously higher percentage of occurrence in postpartum hemorrhage(8.75%),poor wound healing(11.25%),neonatal asphyxia(8.75%)and the puerperal disease(12.50%)than the patients in the control group(1.25%,2.50%,1.25%,3.75%),and the differences were statistically significant(P＜0.05).ConclusionVaginal delivery can be an option for pregnant women with cicatricial uterus.The pregnancy outcomes of reconsidered cesarean section cannot be satisfactory.Natural delivery can be considered for pregnant women with indications of vaginal delivery. 2016 Vol. 23 (36): 76-78 [Abstract] ( 129 ) HTML (36 KB)  PDF  (0 KB)  ( 37 ) 79 Therapeutic effect of ovarian cysts with benign ovarian neoplasms by transvaginal and laparoscopic ZHONG Hua-lan ObjectiveTo explore the effect of transvaginal and laparoscopic in ovarian cyst removal of benign ovarian tumors.MethodsEighty patients with benign ovarian tumors admitted in our hospital from June 2014 to September 2015 were divided into observation group and control group according to the random number table wiwh 40 cases in each group.Observation group and control group were treated by vaginal ovarian cystectomy,laparoscopic ovarian cystectomy treatment respectively,and the clinical results of the two groups was comparied.ResultsThere were no significant differences in the operative time,intraoperative blood loss and complication between the two groups (P＞0.05).However, the postoperative analgesic use,the first exhaust time,the ambulation time in the two groups had statistically significant difference(P＜0.01).ConclusionOvarian cyst and laparoscopic ovarian cysts can be used for the treatment of benign ovarian cysts without any trauma,which is beneficial to the early recovery of the patients.However,the former can achieve the effect without scars and less postoperative analgesic drugs. 2016 Vol. 23 (36): 79-81 [Abstract] ( 111 ) HTML (38 KB)  PDF  (0 KB)  ( 34 ) 82 Clinical effect of the application of laparoscopic conservative therapy in the treatment of ectopic pregnancy ZHANG Yi-feng ObjectiveTo investigate the clinical effect of application of laparoscopic conservative therapy in the treatment of ectopic pregnancy.MethodsNinety-four cases of ectopic pregnancy who were treated in our hospital from January 2015 to February 2016 were selected and divided into two groups according to the admission time.47 cases of the control group were treated with open surgery;while 47 cases of the observation group were treated by laparoscopic conservative surgeries.Both two groups were treated with fallopian tube radiography examinations after the surgery,and the patency rate of fallopian tube was compared between two groups.ResultsThe patency rate of fallopian tube in the observation group(83.0%)was higher than that in the control group(57.4%),the difference was statistically significant(P＜0.05).The volume of intra-operative blood transfusion of the observation group was significantly less than that of the control group,the duration of surgery and length of stay of observation group were significantly shorter than those of the control group,the difference was statistically significant(P＜0.05);no serious complications occurred in two groups of patient.ConclusionLaparoscopic conservative surgery for patients with ectopic pregnancy is significantly effective,those surgical indicators are more excellent compared with open conservative surgery,and increases the patency rate of fallopian tube significantly,it is worthy of clinical promotion. 2016 Vol. 23 (36): 82-84 [Abstract] ( 117 ) HTML (37 KB)  PDF  (0 KB)  ( 30 ) 85 Impact of early enteral breast micro feeding on growth and development of premature infants LONG Chun-gen;YANG Huan-xiu;ZHONG Yan-ling;GUO Zong-rong;CHEN Wen;GUO Fu-yu;ZOU Peng-fei ObjectiveTo study the impact of early enteral breast micro feeding on growth and development of premature infants and gastrointestinal tolerance,and to provide a more reasonable scheme for early nutrition of premature infants.MethodsSixty premature infants from March 2015 to August 2016 in our hospital were selected as study objects,and they were randomly divided into experimental group and control group,with 30 cases in each group.The experimental group was given the feeding 2 h after birth,and the control group was given the feeding 24 h after birth.The growth and development,gastrointestinal tolerance and complications of premature infants in two groups were monitored.ResultsThe time of recovery to birth weight,jaundice subsided,hospital stay and number of infants with feeding intolerance in the experimental group was (8.2±2.5)d,(8.1±1.5)d,(28.5±3.6)d and 5 cases respectively,compared with the control group [(9.7±3.0)d,(10.3±2.3)d,(36.5±6.5)d,12 cases],the difference was statistically significant(P＜0.05).The total incidence rate of complications in the experimental group was 6.7%,was lower than that of the tcontrol group (26.7%),the difference was statistically significant(P＜0.05).ConclusionEarly enteral breast micro feeding can promote the growth and development of premature infants,and with high safety. 2016 Vol. 23 (36): 85-87 [Abstract] ( 126 ) HTML (34 KB)  PDF  (0 KB)  ( 27 ) 88 Analysis of risk factors for extra-pulmonary manifestation of Mycoplasma pneumoniae pneumonia LIU Dao-ying ObjectiveTo analyze the risk factors of Mycoplasma pneumoniae pneumonia.MethodsFrom May 2014 to May 2016,clinical data of 130 cases of Mycoplasma pneumoniae pneumonia treated in our hospital were retrospectively analyzed.The children were divided into two groups according to whether they had extra-pulmonary manifestations∶group 1(extra-pulmonary manifestation group and group 2(non-extra-pulmonary manifestation group),the differences of sex,age,body temperature,slice inspection and laboratory examination results were analyzed,and the risk factors of Mycoplasma pneumoniae pneumonia The Logistic regression analysis was used to determine the risk factors of children with Mycoplasma pneumoniae pneumonia.ResultsAmong the 130 children with Mycoplasmal pneumonia,50 cases (38.46%)were extra-pulmonary manifestation and 80 cases(61.54%)did not appear extra-pulmonary manifestation.Digestive system,nervous system and urinary system were more common;gender,the proportion of body temperature＞38℃and fever period＞10 d of children in the two groups had no statistically significant difference(P＞0.05).There were significant differences in age,MP-IgM,neutrophil count,WBC count and CRP between the two groups(P＜0.05),which were independent risk factors of external manifestations for children with Mycoplasma pneumoniae pneumonia (P＜0.05).ConclusionAge,MP-IgM,neutrophil count,peripheral blood WBC count and CRP are the risk factors of Mycoplasma pneumoniae pneumonia children with pulmonary manifestations,and should pay attention. 2016 Vol. 23 (36): 88-90 [Abstract] ( 134 ) HTML (36 KB)  PDF  (0 KB)  ( 35 ) 91 Efficacy analysis of immunosuppressive agents with topical Recombinant bovine basic fibroblast growth factor on recurrent oral ulcers NIE Jian-fang ObjectiveTo analyze clinical efficacy of recurrent oral ulcers treated by immune agents Levamisole hydrochloride with topical rb-bFGF(recombinant bovine basic fibroblast growth factor).Methods130 patients with recurrent oral ulcers from January 2014 to December 2015 in our hospital were randomly divided into observation group and control group according to treatment around,65 cases in each group.The patients in observation group were treated by Levamisole hydrochloride tablets with rb-bFGF sterile topical sprays,patients in control group were treated by Lvamisole hydrochloride.CD3+,CD4+,CD8+cells in T lymphocytes;helper T lymphocytes（helper T cell Th）,Th1（IFN-γ,TNF-α, IL-2）,Th2（IL-4,IL-6,IL-10）in the serum and the clinical efficacy were compared before and after treatment,the clinical effects of Levamisole hydrochloride tablets with rb-bFGF topical was analyzed for patients with recurrent oral ulcers.ResultsCD3+,CD4+,CD8+,CD4+/CD8+of T lymphocytes in patients of observation group were significant differenres before and after treatment（P＜0.01）,no significant difference in the control group after treatment（P＞0.05）.After treatment,CD3+,CD4+,CD8+,CD4+/CD8+were significant differences between two groups（P＜0.05）.The helper T lymphocytes, Th1（IFN-γ,TNF-α,IL-2）,Th2（IL-4,IL-6,IL-10）,IFN-γ/IL-4 in observation group were significant differences before and after treament（P＜0.01）,in addition to IL-6 was significant differece in the control group（P＜0.01）,others were no significant differences（P＞0.05）.After treatment,INF-α,IL-6,were no significant differences,others were significant differenles （P＜0.05）.Clinical total effective rate was 92.08%,the recurrence rate of 9.23%in observation group,the control group was 73.85%,the recurrence rate of 36.92%,there was significant difference between two groups（P＜0.01）.ConclusionTreatment by Levamisole hydrochloride tablets with b-bFGF topical can effectively improve T lymphocyte subsets and serum helper T lymphocytes expressing for the patients with recurrent oral ulcers and reduce their the recurrence rate. 2016 Vol. 23 (36): 91-94 [Abstract] ( 137 ) HTML (51 KB)  PDF  (0 KB)  ( 42 ) 95 The curative effect of Qingjiefang combination with large dose of Houstonian Cordata on Herpes Sim plexeratitis and impact on patient′s serum and tear index of oxidative stress SHI Yu-jin ObjectiveTo explore the effect of Qingjiefang combination with large dose of Houstonian Cordata on Herpes Sim plexeratitis and impact on serum and tear index of oxidative stress.Methods81 Patients with Houstonian Cordata on Herpes Sim plexeratitis and TCM syndrome type belonging to KangCheng from August 2012 to May 2016 had been randomly into control group(n=40)and observation group(n=41).The control group was treated with Ganciclovir eye drops during the day,with Gel Ganciclovir during the night while the observation group was given Qingjiefang with large dose of herba houttuyniae in addtion,a course of treatment is 30 days,the clinical curative effect was compared.ResultsThe serum,TAC and GSH-PX levels of two groups were higher than those of control group of treatment,MDA was lower than that of control group(P＜0.05).The serum,TAC and GSH-PX levels of the observation group were higher than those of control group,while the level MDA of the observation group was lower than that of control group posttreatment,the difference was siginificant(P＜0.05).The total effective rate of the observation group was higher than that of control group,the difference was siginificant(P＜0.05).The total recurrence rate in six month of control group was higher than that of observation group (P＜0.05).ConclusionThe effect of Qingjiefang combination with Houstonian Cordata on Herpes Sim plexeratitis and impact on patient's serum and tear index of oxidative stress are remarkable,which can improve the oxidative stress reaction and reduce the recurrence rate,it is worthy promoting. 2016 Vol. 23 (36): 95-98 [Abstract] ( 130 ) HTML (44 KB)  PDF  (0 KB)  ( 46 ) 99 Analysis of the clinical application value of tracheal intubation by visual laryngoscopy combined with fiberoptic bronchoscopy in intubation with difficult airway CHEN Hong-wu;CHEN Lin-li;JIANG Feng-yan ObjectiveTo analyze the clinical application value of tracheal intubation by visual laryngoscopy combined with fiberoptic bronchoscopy in intubation with difficult airway.Methods82 patients with difficult airway who were treated in our hospital from September 2014 to September 2016 were selected and randomly divieded into observation group and control group,41 cases in each group.The observation group was intubated by visual laryngoscopy combined with fiberoptic bronchoscopy while the control group was intubated by visual laryngoscopy.The one-time success rate, the time of intubation and the complication rate between two groups were compared,the change of the vital signs before and after intubation were observed.ResultsThe difference of the MAP,HR and SpO2before and 3 minutes after intubation were no significant differenecs in both groups(P＞0.05),the changes of MAP,HR and SpO2between two groups had no statisticant differences(P＞0.05).The time of intubation in observation group was significantly lower than that of control group（t=46.0993，P＜0.01）;the one-time success rate of observation group was 95.12%,which was significantly higher than that of control group of 80.49%（χ2=4.1000，P＜0.05）.The complication rate in observation group was 9.76%, which was significantly lower than that of control group of 31.71%（χ2=6.0109，P＜0.05）.ConclusionThe applicaiton of tracheal intubation by visual laryngoscopy combined with fiberoptic bronchoscopy in difficult airway can significantly enhance the success rate and reduce compllication in intubation with difficult airway. 2016 Vol. 23 (36): 99-101 [Abstract] ( 140 ) HTML (39 KB)  PDF  (0 KB)  ( 34 ) 102 The application comparison of Sufentanil and Remifentanil in painless flexible bronchoscopy with laryngeal mask airway HUANG Hui;WANG Hai-yan;LIN Hui-wen;LIU Di;YE Dan-li;YAN Yuan ObjectiveTo explore Sufentanil and Remifentanil in painless flexible bronchoscopy with laryngeal mask airway.Methods80 ASA I-Ⅲpatients aged 18-70 from March to May 2016 in our tospieal who were scheduled to undergo painless flexible bronchoscopy were randomly divided into Sufentanil group(group S)and Remifentanil group(group R).The adverse events during and after the procedure,the awake time and the satisfaction of the doctor and patients were compared between two groups.ResultsDuring the procedure,there were no significant difference in the cough,body motion,laryngospasm,dislocation of the LMA,hypertension,tachycardia between the two groups(P＞0.05),the incidence rates of hypotension and bradycardia in group R were higher than thoes of group S(P＜0.05),the awake time in group R was shorter than that of group S(P＜0.05),and during the recovery room,the incidence rates of hypertension and tachycardia in group R were higher than that of group S,the SAS score of group R was higher than that of group S (P＜0.05),MAP of group R was lower than that of group at T1,T2,T3,HR of T1,T3was lower than that of group S (P＜0.05).ConclusionSufentanil and Remifentanil can be used in painless flexible bronchoscopy with laryngeal mask airway,comparing to group R,Sufentanil group has more stable haemodynamics and less adverse events during and after procedure,but the awake time is longer. 2016 Vol. 23 (36): 102-104转120 [Abstract] ( 141 ) HTML (48 KB)  PDF  (0 KB)  ( 38 ) 105 Observation of MSCT features of solitary pulmonary ground-glass nodules CHEN Mao-hao;YANG Yue;LIANG Cai-ni;CHEN Xiao-long;CHEN Yu-bin;ZENG Xiao-min ObjectiveTo explore the multi-slice CT (MSCT)features of solitary pulmonary ground-glass nodules.MethodsThe clinical and CT data of 127 patients with solitary pulmonary ground-glass nodules in our hospital from February 2013 to February 2016 were analyzed and divided into two groups according to benign and malignant lesions, 87 cases in benign lesion group and 40 cases in malignant lesion group.The CT signs of two groups of solitary pulmonary ground-glass nodule patients were observed.ResultsSmooth edges and globular nodules in benign lesion group were more seen than that in Malignant Lesion Group,while,the vacuole signs,the solid part,blood vessel trajection and pleural proportion in malignant lesion group was higher than that of the benign lesion group,with significant difference (P＜0.05).ConclusionMSCT can clearly show the morphological characteristics of different types of solitary pulmonary ground-glass nodules,especially the relationship between blood vessel and pleura,which can provide a reliable theoretical basis for clinical diagnosis and treatment. 2016 Vol. 23 (36): 105-107 [Abstract] ( 130 ) HTML (39 KB)  PDF  (0 KB)  ( 46 ) 108 Effect observation of abdominal B-ultrasound combined with vaginal B-ultrasound in the diagnosis of gynecological acute abdomen WANG Yong-ping ObjectiveTo explore the clinical effect of abdominal B-ultrasound combined with vaginal B-ultrasound in the diagnosis of gynecological acute abdomen.Methods97 cases of gynecological acute abdomen from July 2015 to July 2016 in our hospital were selected as the research object,and surgical pathology diagnosis was used as gold standard. All patients were given pure abdominal B ultrasound,abdominal B-ultrasound combined with vaginal B-program for diagnosis.The diagnostic accuracy was compared between the two groups.ResultsThe diagnostic accuracy of abdominal B-ultrasound combined with vaginal B-ultrasound was 92.78%,which was higher than 74.23%of the abdominal B-ultrasound,with significant difference (χ2=12.125，P=0.000).ConclusionThe effect of abdominal B-ultrasound combined with vaginal B-ultrasound in the diagnosis of gynecological acute abdomen is effective,the diagnostic accuracy of different types of acute abdomen in obstetrics and gynecology is higher,and the misdiagnosis and misdiagnosis are less,and the ultrasonic examination is convenient and practical and economy.which can be used as an ideal gynecological acute abdomen detection means. 2016 Vol. 23 (36): 108-110 [Abstract] ( 154 ) HTML (35 KB)  PDF  (0 KB)  ( 32 ) 111 Value of abdominal ultrasonography in the diagnosis of neonatal necrotizing enterocolitis DONG Jin-ying ObjectiveTo explore the effect of abdominal ultrasonography in the diagnosis of neonatal necrotizing enterocolitis(NEC).Methods60 cases of neonatal necrotizing enterocolitis in our hospital from January 2015 to January 2016 were selected as the research object.According to the modified Bell-NEC classification criteria,all patients were divided into the suspected group and the confirmed group,30 cases in each group.Abdominal X-ray and abdominal ultrasonography were performed in two groups,and the results were compared.ResultsIn the suspected group,the detection rate of the intestinal wall pneumatosis and portal venous gas with abdominal ultrasound examination was higher than that with abdominal X-ray,with significant difference(P＜0.05).In addition,there were 12 cases(40.00%)of intestinal peristalsis slowed down in abdominal ultrasonography,and intestinal peristalsis disappeared in 5 cases (16.67%),and ascites was found in 8 cases(26.67%).In the diagnosis group,the detection rate of the intestinal wall pneumatosis and portal venous gas with abdominal ultrasound examination was higher than that with abdominal X-ray,with significant difference (P＜0.05).In addition,there were 16 cases (53.33%)of intestinal peristalsis slowed down in abdominal ultrasonography,and intestinal peristalsis disappeared in 9 cases(30.00%),and ascites was found in 6 cases(20.00%).ConclusionThe use of abdominal ultrasonography in the diagnosis of NEC compared with abdominal X-ray has a better effect on the detection of intestinal wall gas and portal venous gas,which is worthy of clinical application and promotion. 2016 Vol. 23 (36): 111-113 [Abstract] ( 116 ) HTML (35 KB)  PDF  (0 KB)  ( 36 ) 114 Clinical effect of Amlodipine Atorvastatin Calcium Tablets treating hypertension complicated with coronary heart disease AI Jian-hua ObjectiveTo analyze the clinical effect of Amlodipine Atorvastatin Calcium Tablets treating hypertension complicated with coronary heart disease.Methods108 patients with hypertension complicated with coronary heart disease treated by our hospital from July 2015 to July 2016 were selected as objects,and they were randomly divided into two groups,each group had 54 cases.The control group was given Extended Release Tablets of Nifedipine,while the observation group was given Amlodipine Besylate and Atorvastatin Calcium Tablets,after 2 months,blood lipid indexes, clinical effect 1 and 2 months of treatment,inflammatory indexes and adverse reactions after treatment between two groups were compared.ResultsCompared with the control group,LDL-C,TG,TC value was lower and HDL-C value was higher after treatment in the observation group (P＜0.05).After treatment,the IL-6,vWF,NO,ET index in the observation group compared with the control group was statistically significant(P＜0.05),it had no statistically significant differences in the level of CRP and TNF-α (P＞0.05).The total effective rate of the observation group was higher than that of the control group(P＜0.05).There was no significant difference in the incidence rate of adverse reactions between two groups (P＞0.05).ConclusionAmlodipine Besylate and Atorvastatin Calcium Tablets treating hypertension complicated with coronary heart disease can achieve a relatively significant clinical effect,and it can lower blood lipid,eliminate inflammatory factors with high safety,and it is worthy of further promotion. 2016 Vol. 23 (36): 114-116 [Abstract] ( 149 ) HTML (41 KB)  PDF  (0 KB)  ( 34 ) 117 Effect of dopamine combining with dobutamine on treating infantile severe pneumonia and their influence on inflammatory response XIE Zheng;ZHANG Xiao-qing ObjectiveTo analyze the effect of dopamine and dobutamine in the treatment of children with severe pneumonia and their influence on inflammatory reaction.MethodsSeventy-eight children with severe pneumonia from October 2014 to May 2016 admitted into our hospital were selected and evenly divided into two groups by a random number table,observation group and control group,with 39 cases in each group.In the control group,regular treatments including oxygen inhalation,anti-infection,cough arresting and asthma relieving,correction of acid-base balance and electrolyte disorders were used.In the observation group,on the basis of the control group,dopamine combining with dobutamine was added for the treatment.The clinical effect and serum inflammatory factor level in the two groups were compared.ResultsThe effective rate in the observation group was 94.87% (37/39),much higher than that in the control group accounting for 79.49%(31/39),the difference was statistically significant(P＜0.05).In the observation group,levels of IL-6, TNF-α,and C-reactive protein (CRP)after treatment were greatly decreased in comparison with that before treatment and that in the control group after treatment,the differences were statistically significant(P＜0.05).ConclusionDopamine combining with dobutamine can obtain a remarkable effect on treating pediatric severe pneumonia and can significantly improve the clinical symptoms in children and inhibit the inflammatory response,which is worthy of promotion and application in clinic. 2016 Vol. 23 (36): 117-119 [Abstract] ( 141 ) HTML (42 KB)  PDF  (0 KB)  ( 36 ) 121 Screening of Chinese herbal medicine for antibacterial anti-inflammatory in department of gynaecology and preclinical experimental study ZUO Chun-lian;HAN Cheng-yun;LIU Zhi-kai;YAN Qu-ru ObjectiveTo study the drug of treating gynecological reproductive system infection,and screen the Chinese herbal medicine with very good antibacterial anti-inflammatory effect.MethodsFour kinds of Chinese herbal medicines were selected as the antibacterial and antiphlogistic drugs∶Dendropanax dentiger Merr.,Lycopodium japonicum Thunb, Usnea diffracta Vain,Pholido-ta cantonensis Rolfe.They were extracted by water extraction and ethanol extraction,and then they were mixed into the same concentration solution.The group was the treatment group of Chinese herbal medicine(n=25),and water CK1 and ethanol CK2 control group(n=25)respectively.Escherichia coli,Staphylococcus aureus,Staphylococcus aureus were Cultured,and the bacteriostatic ring was determined of Chinese herbal medicine extract by tube plate method to evaluate the bacteriostatic effect.ResultsAmong 4 kinds of water extract of Chinese herbal medicine,Lycopodium japonicum Thunb had the best bacteriostatic effect,and it had a very obvious bacteriostatic effect for 3 kinds of bacteria,and there was a statistical difference compared with control group(P＜0.01),and bacteriostatic effect of Dendropanax dentiger Merr.was stronger for Staphylococcus aureus,and there was a statistical difference of bacteriostatic effect compared with control group (P＜0.05),Usnea diffracta Vain was following,and there was a statistical difference compared with control group (P＜0.05).Among 4 kinds of alcohol extract of Chinese herbal medicine,Dendropanax dentiger Merr.had the best bacteriostatic effect,and it had a very obvious bacteriostatic effect for 3 kinds of bacteria,and there was a statistical difference compared with control group (P＜0.05),and bacteriostatic effect of alcohol extract for Dendropanax dentiger Merr.and Usnea diffracta Vain was almost quite,and there was a tatistical difference compared with comtrol group(P＜0.05).ConclusionBacteriostatic effect of alcohol extract of Dendropanax dentiger Merr. and Usnea diffracta Vain and the water extract of Lycopodium japonicum Thunb is obvious which is suitable for external use in clinical obstetrics and gynecology.Oral water decoction juice of Dendropanax dentiger Merr.for oral admina has an antibacterial anti-inflammatory in clinic. 2016 Vol. 23 (36): 121-124 [Abstract] ( 134 ) HTML (53 KB)  PDF  (0 KB)  ( 37 ) 125 Determinination of konjac glucomannan in konjac refined powder by HPLC CHEN Yan-jie;CHU Yin-ling;HAN Chao-yi;ZHANG Jie ObjectiveTo establish an HPLC method for content determination of konjac glucomannan (KGM)in konjac refined powder,and compare with results of colorimetric assay.MethodsKGM was hydrolyzed with H2SO4(2.5 mol/L) at 110℃for 2 hours,which reacted with 1-phenyl-3-methyl-5-pyrazolone (PMP)before HPLC separation and formed two monosaccharides,D-mannose and D-glucose.HPLC was performed on the column of TOSOH TSK-GEL ODS with gradient elution of mobile phase A (acetonitrile)and mobile phase B (0.45 g potassium dihydrogen phosphate,0.5 ml TEA,100 ml acetonitrile,900 ml water,pH=7.5).The flow rate was 1.0 ml/min,detection wavelength was 250 nm,and column temperature was 30℃.Colorimetric method was tested with reference to GB/T18104-2000.ResultsLinearity of D-mannose was good in range of 21.2-159.3 μg(r=0.9998);while D-glucose in range of 21.5-154.2 μg (r=0.9999).The average recovery of KGM was 98.9% (RSD 2.2%).The contents were less 5%-7%than that by colorimetry.ConclusionHPLC method is more accurate than colorimetry to determine content of KGM in konjac refined powder,and would be better for quality control and grading of konjac refined powder. 2016 Vol. 23 (36): 125-128 [Abstract] ( 109 ) HTML (45 KB)  PDF  (0 KB)  ( 33 ) 129 Determination method of content of chelerythrine in Weitongping Capsules DUAN Shu-qing;LIU Wei;YIN Zhan-fang ObjectiveTo establish a method for the determination of chelerythrine in Weitongping Capsules.MethodsThe content of chelerythrine in Weitongping Capsules was determined by high performance liquid chromatography (HPLC).The chromatographic column was Agilent XDB-C18(4.6 mm×150 mm,2.5 μm).The mobile phase was acetonitrile-1%triethylamine solution (26∶74;pH value re-adjusted to 3.0).The detection wavelength was 269 nm,the column temperature was 25℃,the flow rate was 1.0 ml/min,and the injection volume was 10 μl.ResultsLinear range of chelerythrine was 2.62-43.67 μg/ml(r=0.9999).The average recovery was 98.88%and RSD was 1.91%(n=9).ConclusionThe established method is accurate,sensitive and simple,in good stability and reproducibility,and specificity,which can control the quality of Weitongping Capsule in a better way. 2016 Vol. 23 (36): 129-131转141 [Abstract] ( 137 ) HTML (42 KB)  PDF  (0 KB)  ( 34 ) 132 Clinical effect of Modified Zhitong Rushen Decoction in the treatment of postherpetic neuralgia CHEN De-jian ObjectiveTo explore clinical curative effect of Modified Zhitong Rushen Decoction in the treatment of postherpetic neuralgia.Methods60 cases of postherpetic neuralgia in our hospital from January 2013 to June 2015 were selected and divided into the treatment group and the control group according to random number table method,30 cases in each group.The control group was treated with conventional oral Pregabalin,Vitamin B1,Methylcobalamin Dispersible Tablets,the treatment group was treated with Modified Zhitong Rushen Decoction on the basis of the control group,the effect of the two groups was compared.ResultsThe total effective rate of the treatment group was 90.00%,which was higher than 76.67%of the control group,with significant difference (P＜0.01).The VAS,QS,SDS and SAS scores after treatment of the treatment group was lower than that of the control group after treatment,with significant difference (P＜0.05).The total satisfaction degree of the treatment group was 76.67%,which was higher than 43.33%of the control group,with significant difference (P＜0.01).The total recurrence rate of the treatment group was 7.4%,which was lower than 26.1%of the control group,with significant difference (P＜0.01).ConclusionModified Zhitong Rushen Decoction combined with Pregabalin in the treatment of postherpetic neuralgia can effectively improve the curative effect,relieve pain,improve satisfaction,reduce the recurrence rate. 2016 Vol. 23 (36): 132-134 [Abstract] ( 132 ) HTML (45 KB)  PDF  (0 KB)  ( 36 ) 135 Clinical effect analysis of Chaiqin Bazheng Powder combined with Piperacillin/Tazobactam Sodium in the treatment of patients with urinary tract infection SUN Wen-cai;MI Hai ObjectiveTo explore the clinical effect of Chaiqin Bazheng Powder combined with Piperacillin/Tazobactam Sodium in the treatment of patients with urinary tract infection.Methods80 patients with urinary tract infection from January 2015 to June 2016 in our hospital were selected and randomly divided into the control group and the treatment group,40 cases in each group.The control group was given Piperacillin/Tazobactam intravenous drip,the treatment group was given Chaiqin Bazheng Powder on the basis of the control group.The effect of the two groups was compared.ResultsThe total effective rate of the treatment group was 92.50%,which was higher than 72.50%of the control group,with significant difference (P＜0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups (P＞0.05).ConclusionClinical effect of Chaiqin Bazheng Powder combined with Piperacillin/Tazobactam Sodium in the treatment of patients with urinary tract infection is better than that of Piperacillin/Tazobactam Sodium. 2016 Vol. 23 (36): 135-137 [Abstract] ( 130 ) HTML (40 KB)  PDF  (0 KB)  ( 38 ) 138 Determination of calcitonin original application in patients with syphilis diagnosis and treatment LAI Qi-wei;LIU Qiang;LEI Xing;WANG Li-li;JIANG Yun;LU Cong;HUANG Li-fang;WEN Tai-pei ObjectiveTo explore the calcitonin original determination application in patients with Syphilis diagnosis and treatment.MethodsFrom January 2015 to September 2016,151 patients with Syphilis（observation group）were given immunofluorescence chromatography,160 patients healthy subjects were sleeted at the same time as control group. The changes of serum procalcitonin PCT level was compared between the two groups.ResultsPCT in the observation group was（8.7±1.1）ng/ml and the control group was（0.3±0.1）ng/ml before the treatment,the difference was significant （t=96.182,P=0.000）.The positive rate of PCT was 93.9%in the patients with stageⅠSyphilis in the observation group, the positive rate of PCT was 60.0%in the patients with stageⅡ Syphilis,the positive rate of PCT was 42.1%in the patients with stageⅢSyphilis,the positive rate of PCT was 20.0%in the patients with latent Syphilis,the positive rate of PCT was 90.9%in the patients with congenital Syphilis,and the positive rate of PCT was 84.6%in the patients with pregnancy Syphilis,there were significant differences（χ2=99.901,P=0.000）.ConclusionThe application value of procalcitonin determination in the diagnosis and treatment of Syphilis is of great value,which can provide important information for the clinical diagnosis and treatment. 2016 Vol. 23 (36): 138-141 [Abstract] ( 143 ) HTML (44 KB)  PDF  (0 KB)  ( 34 ) 142 Study the correlation between sex hormones changed and male patients with type 2 diabetes mellitus CHEN Shan-shan;LI Xin-de;LIN Qi-ling ObjectiveTo explore the correlation between sex hormones changed and male patients with type 2 diabetes mellitus.MethodsFrom June 2013 to July 2015,78 male patients with type 2 diabetes who received treatment in our hospital were studied.According to the properties of age,they were divided into 5 groups for every 10 years;they were also divided into fat group and not fat group by body mass index,the other one was not fat;according to the severity of erectile dysfunction,the patients were also divided into none ED,mild ED group,moderate ED group,severe ED group. The relationship between sex hormone levels and male T2DM patients was studied by detecting changes in the levels of sex hormones.ResultsThe level of sex hormones was not influenced by age,all the data had no relation,and the data were no significant differences(P＞0.05).The level of sex hormones was influenced by fat,the data of testosterone,folliclestimulating hormone and luteinizing hormone in the fat group were lower than not fat group(P＜0.05),while estradiol of fat group was higher than that of not fat group(P＜0.05).levels of FSH and LH increased with the increase of severity of ED,while T and E2were decreased (P＜0.05).ConclusionThe level of sex hormones has correlation with the fat,and the male patients with type 2 diabetes will influence the function of gonad. 2016 Vol. 23 (36): 142-144 [Abstract] ( 106 ) HTML (36 KB)  PDF  (0 KB)  ( 36 ) 145 Application of serum C peptide and glycosylated hemoglobin examination in the diagnosis of diabetes LUO Xing-yan ObjectiveTo explore the application of serum C peptide and glycosylated hemoglobin examination in the diagnosis of diabetes.Methods60 patients with diabetes in our hospital from August 2014 to August 2016 were received as the research object,set as observation group,including 30 patients with type 2 diabetes so as simple diabetes group,30 patients with diabetic nephropathy in diabetic nephropathy group,30 cases of healthy in our hospital at the same time were selected for a medical examination of subjects as control group,all the research object of serum C peptide, glycosylated hemoglobin test,blood sugar levels,serum c-peptide levels of simple diabetes group,diabetes,nephropathy group and control gorup were compared.ResultsThe fasting blood glucose,2 h postprandial blood glucose levels of simple diabetes group and diabetic nephropathy group were significantly higher than those of control group,there were significant differences(P＜0.05).Pure fasting blood glucose levels in patients with diabetes mellitus group,2 h postprandial blood glucose level and diabetic nephropathy had no significant difference(P＞0.05).Serum C peptide of simple diabetes group and diabetes nephropathy group were lower than those of control group,glycosylated hemoglobin was significantly higher than that of control group(P＜0.05).Serum C peptide of simple diabetes group was higher than that of diabetic nephropathy group,glycated hemoglobin was lower than that of control group,the difference was significant(P＜0.05).ConclusionSerum C peptide and glycosylated hemoglobin examination has high valuein the diagnosis of diabetes, it is worthy of popularization and application. 2016 Vol. 23 (36): 145-147 [Abstract] ( 123 ) HTML (37 KB)  PDF  (0 KB)  ( 32 ) 148 Investigation of the reasons for the interruption of postpartum pelvic floor muscle rehabilitation therapy and the understanding degree of related knowledge about the recovery of the pelvic floor and the countermeasures JIANG Wei-min ObjectiveTo explore the reasons for the interruption of female pelvic floor muscle rehabilitation therapy and and the understanding degree of related knowledge about the recovery of the pelvic floor to put forward effective measures in order to reduce the female pelvic floor muscle rehabilitation treatment interruption rate,to improve the health of women.Methods134 cases of self interruption pelvic floor muscle stimulation combined with pelvic floor muscle exercise from June 2010 to April 2016 in our hospital were selected as the research objects.The understanding degree of related knowledge about the recovery of the pelvic floor rehabilitation was understood through the questionnaire survey,and the corresponding health education was given.ResultsThe main reason for the interruption of the pelvic floor muscle rehabilitation was"knowledge of pelvic floor muscle rehabilitation was completely not understood",and it accounted for 82.1%," time could not be arranged"accounted for 36.4%,secondly,"shy"and"short term was difficult to achieve the desired"" higher cost"accounted for 27.5%,16.3%,12.0%respectively.After the health education,the understanding degree of related knowledge about the recovery of the pelvic floor rehabilitation training of pregnant women was more and more indepth,and compared before the health education,the difference was statistically significant(P＜0.05).After the health education,the proportion of pregnant women who wanted to understand the relevant knowledge of pelvic floor rehabilitation training was significantly improved,compared before the health education,the difference was statistically significant(P＜0.05).ConclusionAlthough there are many causes of female pelvic floor muscle rehabilitation treatment interruption,but most of them are solved by adjusting treatment.After health education,thecomprehensive degree of related rehabilitation knowledge in pregnant women was significantly higher.The feasibility of pelvic floor muscle rehabilitation treatment is very high,which can greatly improve the female pelvis health degree,it is worth popularizing and applying. 2016 Vol. 23 (36): 148-150转158 [Abstract] ( 134 ) HTML (43 KB)  PDF  (0 KB)  ( 37 ) 151 Analysis on epidemiological characteristics of epidemic hemorrhagic fever in Guanyun County in 2010-2014 CHEN Shou-juan;YAN Chun-hua ObjectiveTo master the epidemiological characteristics of epidemic hemorrhagic fever（EHF）in Guanyun County,to provide scientific basis for prevention and control measures of EHF.MethodsThe case data (from January 2010 to December 2014)were collected from Guanyun County Center for Disease Prevention and Control,and the population data were collected from Guanyun County Bureau of statistics.The statistical analysis was performed by descriptive epidemiological method.ResultsA total of 24 EHF cases were reported in 2010-2014,and the average incident rate was 4.77/100 thousand.Compared with the previous five years of 2005-2009,it showed an upward trend.The highest incidence rate was 5.96/100 thousand in 2014,and the mortality rate was 3.28%(8/244).Incidence of male and female ratio was 2.08∶1,the age of onset was 17-81 years old,18-59 years old population accounted for 66.39% (162/244).More farmers occurred,accounting for 94.67% (231/244).Cases occurred in winter and spring.County each villages and towns had a case report,Nangang,Longju,Yishan,Xiache,Yangji and Dongwangji these six towns,EHF cases accounted for 62.70%(153/244)of the total cases.ConclusionPestilence of EHF in Guanyun County is on the rise.It should vigorously carry out the prevention and control measures such as rodent and focus groups vaccination,so as to effectively minimize the harm of EHF. 2016 Vol. 23 (36): 151-153 [Abstract] ( 146 ) HTML (40 KB)  PDF  (0 KB)  ( 33 ) 154 Rational use of drugs present situation analysis of 22 township health center in Jiujiang City WEI Ling;SHEN Dong-mei;WAN Zhao-lei;CAI Jie-qing;XIANG Xiao-mei ObjectiveTo analyze the existing problems and irrational use of drugs in township health center prescription review in our city,and to put forward some targeted suggestions for the quality improvement.MethodsFrom September to October 2015,22 township health center were selected from 10 counties and 2 districts of our city by expert group of Health and Family Planning Commission in Jiujiang City.Combination of investigation,assessment and talk was used to investigate the development and rational use of prescription review.Results22 township health center carried out the work of prescription review,but the level is different,the reasonable rate of outpatient prescriptions and hospital doctor′s advice was lower.ConclusionHealth administrative departments should further strengthen the supervising for prescription review of township health center.Improving the status quo of drugs rational use in hospitals,internal management of medical institutions needs to be improved,and to further strengthen the training of rational drug use knowledge and skills of medical staff,improve the rational use of drug system construction,construct and implement the performance evaluation system of prescription review,train the ability of farmers rational drug awareness. 2016 Vol. 23 (36): 154-158 [Abstract] ( 149 ) HTML (49 KB)  PDF  (0 KB)  ( 31 ) 159 The application effect of translational folding robotic surgical instrument vehicle CHANG Ying;LI Jia;LI Yu;LIU Yan-jiang ObjectiveTo evaluate the effect of translational folding robotic surgical instrument vehicle based on the three-dimensional design software CATIA in the operation coordination of robot.MethodsThe translational folding surgical instrument vehicle was established through the CATIA 3D design software.From November 2014 to October 2015,100 patients were underwent robotic surgery in our hospital.By operative sequences,50 cases were given common instrument vehicle were selected as control group and the other 50 cases were given the translational folding surgical instrument vehicle as observation group.Operation preparation time and satisfaction degree of medical staff between two groups were compared.ResultsThe operation preparation time of observation group was(29.95±2.95)minutes was significantly shorter than the control group [(55.89±6.31)minutes](P=0.000).Physician satisfaction of the observation group and the control group was(93.36±3.38)points,(91.61±4.36)points respectively,and there was no statistical difference(P＞0.05),while the nurse satisfaction of two groups was(93.71±3.38)points and（90.90±4.50）points respectively, and there was a statistical difference(P＜0.05).ConclusionThe design theory of translational folding surgical instrument vehicle based on the three-dimensional design software CATIA is more plentiful,and it can shorten the operation time and improve the satisfaction degree of medical staff and is suitable for the operation of medical staff.It is worthy of clinical promotion. 2016 Vol. 23 (36): 159-161 [Abstract] ( 130 ) HTML (40 KB)  PDF  (0 KB)  ( 33 ) 162 Impact of oral health education in outpatient on children′s dental health on and pit and fissure sealing effect LI Zhou-bi ObjectiveTo survey the impact of oral health education in outpatient on children′s dental health and pit and fissure sealing effect.Methods200 children given infusion in outpatient clinic transfusion room from July to September 2015 in Foshan Stomatological Hospital were selected and were randomly divided into education group(100 cases)and non education group (100 cases)according to the random number table method.Patients in education group were given dental health education.There was no propaganda and education in non education group.After 1 year,the test children were followed up.The same questionnaire was filled by test children and took back.The survey results were counted.ResultsUnderstanding rate of dental health care knowledge and dental hygiene situation in education group children were obvious better than those in non education group children,and the difference was statistical significance (P＜0.05).The detection rate of calculus,dental caries rate,incidence rate of gingivitis,plaque index and pit and fissure sealing in children of education group were obvious better than those in non education group,and the difference was statistical significance (P＜0.05).ConclusionOutpatient oral health education for children can correct bad habits,improve oral health status and is worth to be popularized in clinic. 2016 Vol. 23 (36): 162-163转166 [Abstract] ( 133 ) HTML (33 KB)  PDF  (0 KB)  ( 38 ) 164 Effect of Tetrandrine in the treatment of pulmonary dust disease and its influence on immune function YANG Wei ObjectiveTo evaluate the efficacy of Tetrandrine in the treatment of pulmonary dust disease and its influence on immune function.MethodsFrom December 2013 to December 2015,70 patients with pulmonary dust disease were enrolled in our hospital and divided into control group (n=35)and experimental group (n=35)in random.In the control group,Xifeining Tablets were used,while in the experimental group,Tetrandrine was adopted.The clinical effect, incidence rate of upper respiratory infection and pulmonary infection,and immunity index between two groups were compared.ResultsIn the control group,the total effective rate was 74.29%,and it was much lower than that in the experimental group accounting(97.14%)(P＜0.05).After therapy,CD4 was greatly increased and CD8 was decreased in the experimental group while in the control group,CD4 and CD8 were not displayed statistical difference compared with before treatment and there was a significant difference of CD4 and CD8 between two groups(P＜0.05).The incidence rate of upper respiratory infection and pulmonary infection rate was 54.29%and 28.57%respectively,and it was much higher than those in the experimental group(28.57%,5.71%)(P＜0.05).ConclusionTetrandrine in the treatment of pulmonary dust disease can remarkably alleviate cough,chest pain,and shortage of breath of patients,improve immunity function for patients,and decrease the occurrence rate of upper respiratory infection and pulmonary infection. 2016 Vol. 23 (36): 164-166 [Abstract] ( 137 ) HTML (38 KB)  PDF  (0 KB)  ( 31 ) 167 Application study of holistic pedagogy method in pharmacy teaching ZHANG Lei;MAO Dong-dong;CHEN Qiu Pharmacy is an important professional courses for pharmaceutics students,which is systematic and practical strong,not easy to digest.Based on this problem,this paper put forward the idea and implementation steps of holistic pedagogy.Holistic Pedagogy has an important characteristic in emphasizing the contact of the overall knowledge,radiation from a point to the whole,and thus form a network of knowledge.It will be a perfect form to link the knowledge between horizontal and vertical and cognition and memory in line with the law of knowledge.To some extent it will improve the students′learning enthusiasm and pharmacy teaching.The holistic pedagogy has great advantages for pharmacy teaching and also useful for other pharmacy disciplines. 2016 Vol. 23 (36): 167-169 [Abstract] ( 133 ) HTML (38 KB)  PDF  (0 KB)  ( 35 ) 170 Classroom teaching idea and practice of Chinese medicine effect dynamics ZHANG Ru-yi;YOU Qiu-yun Chinesemedicineeffectdynamicsisachapterfromgeneralintroductionin PharmacologyofChineseMateriaMedica for pharmacy major in medical and pharmic universities and colleges.As one of the main contents,it also acts as a bridge of cross-disciplinary communication and plays an important role in the systematic study of Chinese herbs and research and development of Chinese materia medica preparation.In order to help students to better understand the contents in this chapter and apply these contents into real life and clinical practice,this paper did some explorations of teaching methods on Chinese medicine effect dynamics,classroom teaching idea of Chinese medicine effect dynamics was explored. 2016 Vol. 23 (36): 170-172 [Abstract] ( 133 ) HTML (36 KB)  PDF  (0 KB)  ( 28 ) 173 Effect assessment of evidence-based nursing on patients with acute myocardial infarction complicated with arrhythmia FU Feng ObjectiveTo explore the application effect of evidence-based nursing on patients with acute myocardial infarction complicated with arrhythmia.Methods81 cases of acute myocardial infarction complicated with arrhythmia in the Department of Internal Medicine in our hospital from October 2014 to October 2016 were selected and divided into the experimental group(40 cases)and the control group(41 cases)according to admission sequence.The control group was given conventional nursing,and the experimental group was given evidence-based nursing.The nursing effect and satisfaction degree of the nursing work were compared between the two groups.ResultsThe bed time and hospital stay in the experimental group was shorter than that in the control group,with significant difference (P＜0.05).The incidence rate of arrhythmia in the experimental group was 12.50%,which was lower than 70.73%in the control group,with significant difference (P＜0.05).The heart function of the experimental group was better than that of the control group,with significant difference (P＜0.05).The nursing satisfaction degree of the experimental group was 95.00%,which was higher than 80.49%of the control group,with significant difference(P＜0.05).ConclusionEvidence-based nursing can improve the cardiac function of patients with acute myocardial infarction and arrhythmia,and has a significant effect on reducing the incidence of arrhythmia,and it is worthy of clinical promotion and application. 2016 Vol. 23 (36): 173-175 [Abstract] ( 146 ) HTML (39 KB)  PDF  (0 KB)  ( 33 ) 176 Psychological problems and nursing countermeasures of patients with breast cancer HUANG Shi-fang ObjectiveTo investigate the psychological state and nursing counter measures of patients with breast cancer.MethodsClinical data of 60 patients with breast cancer treated in our hospital from July 2014 to July 2015 were retrospectively analyzed.Patients were divided into intervention group and control group by the different nursing measures,each of 30 cases.Patients in the control group were given the routine care;the intervention group was given comfort nursing intervention measures on the basis of routine nursing.SDS and SAS were used to assess the level of depression and anxiety in patients at the time of admission and discharge.FACT-B was used to evaluate the quality of life of patients;nursing satisfaction was compared between the two groups.ResultsScores of SDS and SAS of the two groups before nursing intervention had no significant difference (P＞0.05).After nursing intervention,the scores of SDS and SAS of patients in the two groups were decreased significantly compared with before nursing intervention,and the intervention group was significantly lower than that of the control group,the differences were statistically significant(P＜0.05). After nursing intervention,the scores and the total score of FACT-B of the intervention group were significantly higher than those of the control group,and the difference was statistically significant(P＜0.05).The nursing satisfaction of the intervention group was significantly higher than that of the control group,the difference was statistically significant(P＜0.05).ConclusionThe effective nursing intervention measures can improve the anxiety and depression of patients with breast cancer and other negative mental state,contribute to the improvement of the quality of life,promote the recovery of patients,improve the nursing satisfaction. 2016 Vol. 23 (36): 176-178转181 [Abstract] ( 123 ) HTML (39 KB)  PDF  (0 KB)  ( 33 ) 179 Effect of integrated traditional Chinese and Western medicine nursing on improving the bad mood and delivery outcome of parturient CHEN Xi-mei ObjectiveTo explore the effect of integrated traditional Chinese and Western medicine nursing on improving the bad mood and delivery outcome of parturient.Methods100 parturient with threatened labor and negative emotions from May 2015 to May 2016 in our hospital were selected and randomly divided into the observation group and the control group,50 cases in each group.The control group was given routine nursing,while the observation group was given birth process of traditional Chinese medicine on the basis of the routine nursing care.The time of labor,the occurrence of negative emotion and the outcome of delivery were compared between the two groups.ResultsThe first,second,third labor time and the total labor time in the observation group was shorter than that in the control group,with significant difference(P＜0.05).The incidence rate of adverse mood in the observation group was 14%,which was lower than 72%in the control group,with significant difference (P＜0.05).The incidence rate of neonatal asphyxia,distress and postpartum hemorrhage in the observation group was lower than that in the control group,with significant difference (P＜0.05).ConclusionIntegrated traditional Chinese and Western medicine nursing has a significant role in improving maternal adverse emotions and delivery outcomes,which is worthy of clinical promotion and application. 2016 Vol. 23 (36): 179-181 [Abstract] ( 124 ) HTML (36 KB)  PDF  (0 KB)  ( 29 ) 182 Analysis on the application of comprehensive nursing intervention in the treatment compliance of patients with leukemia FENG Gui-juan;CAI Yu ObjectiveTo explore the effect of nursing intervention on the treatment compliance of the children′s leukemia.Methods90 admissions of children with leukemia from May 2015 to June 2016 in our hospital were selected as the object of study,they were randomly divided into observation group and control group by using double blind method,45 cases in each group.Comprehensive nursing intervention was given to the observation group of children,the basic nursing care was used to the control group,two groups of children with treatment compliance and the parents of the children′s satisfaction with the degree of satisfaction were compared.ResultsThe treatment compliance of the observation group was 91.11%,better than that of the control group of 73.33%,the difference was significant(χ2=4.865,P＜0.05),the parents′satisfaction in observation group was 95.56%,significantly higher than that of control group of 80.00%,the difference was significant(χ2=5.075,P＜0.05).ConclusionIn the clinical treatment of children with leukemia,using comprehensive nursing intervention,improve the effect treatment,accelerate the progress of treatment,shorten the length of stay,and is worthy of application. 2016 Vol. 23 (36): 182-184 [Abstract] ( 120 ) HTML (39 KB)  PDF  (0 KB)  ( 30 ) 185 The application effect of quality control circle on reducing the incidence of pressure ulcer in patients with fracture HUANG Xiao-lan ObjectiveTo investigate the application effect of quality control circle activity on reducing the incidence of pressure ulcer in patients with fracture.MethodsBefore QCC from January to October 2014,70 cases of fracture hospitalized patients in the department of orthopedics were randomly selected as the control group.After QCC activities from November 2015 to August 2016,70 cases of fracture hospitalized patients in the department of orthopedics were randomly selected as the observation group.The control group were implemented orthopedic routine nursing,and the observation group were carried out QCC on the basis of the control group.The pressure ulcer rate,prevention from pressure ulcer and patients on nursing service satisfaction degree of two groups were observed.ResultsThe incidence of pressure ulcer in the observation group and the control groups respectively were 5.71%,17.14%.The observation group was significantly lower than that of control group (χ2=4.516,P=0.034).The rate of nursing service satisfaction in the observation group was 95.71%,significantly higher than that of control group 85.71%(χ2=4.155,P=0.042).ConclusionThe implemention of quality control circle can significantly reduce the incidence of pressure ulcer in patients with fracture.It also can improve the ability of nurses to prevent pressure ulcer and the satisfaction degree of patients to nursing service. 2016 Vol. 23 (36): 185-187 [Abstract] ( 119 ) HTML (42 KB)  PDF  (0 KB)  ( 39 ) 188 On patients with cluster intervention strategies in the application of central venous catheter nursing value XIA Yan-ling;XU Li-zhen;XU Wen;FU Juan;ZHANG Hui-ling;XIONG Yan ObjectiveTo explore the application value of cluster intervention strategies in central venous catheter care patients.Methods240 patients with central venous catheter from January 2014 to September 2016 were selected and divided into two groups according to the single and double number lottery,120 cases in each group,the patients of control group were given routine nursing care,the patients of observation group were taken cluster intervention strategy,two groups of nursing effect were compared.ResultsThe CRBSI infection rate of observation group was 1.67%,less than 10.83%in the control group (P＜0.05).Accidental tube at a rate of observation group was 0.83%,less than 5.83%in the control group(P＜0.05).Subclavian venipuncture at a rate of observation group was 71.67%,up from 40.00%in the control group (P＜0.05).Total and average hospitalization time and indwelling catheter time were shorter than those of control control group(P＜0.05).ConclusionCluster in the central venous catheter nursing intervention strategy is applied to effect is better,therefore,it is worthy of clinical popularization and application. 2016 Vol. 23 (36): 188-190 [Abstract] ( 106 ) HTML (41 KB)  PDF  (0 KB)  ( 30 ) 191 Perioperative care for patients with cerebral aneurysms interventional vascular embolization treatment DU Jie ObjectiveTo explore the effect of perioperative nursing intervention for the patients with cerebral aneurysms interventional vascular embolization.Methods60 cases of CA from January 2013 and December 2015 in our hospital were selected and treated,all patients were performed interventional vascular embolization.According to random number table method,they were divided into observation group(30 cases,perioperative comprehensive nursing intervention)and control group (30 cases,the conventional nursing intervention).Two groups of postoperative recovery effect were compared; two groups of postoperative complications,intracranial hemorrhage,and length of hospital stay and symptoms disappear time indicator were observed;two groups of preoperative and postoperative satisfaction Glasgow coma scale(GCS)and their families were compared.ResultsThe recovery situation of observation group was better than that of observation group, the difference was significant(P＜0.05).Incidence of postoperative complications and observe group again after six months of intracranial hemorrhage rate were lower than those of control group,and the length of hospital stay,symptoms disappear time were significantly shorter than those of control group(P＜0.05);GCS score in observation group was better than that of control group and observation group family nursing satisfaction was 93.3%,the control group in family satisfaction was 73.3%,significantly higher than that of control group(P＜0.05).ConclusionIn patients with cerebral aneurysms interventional embolization for perioperative nursing,patients recover quickly,fewer complications,high satisfaction,help to improve the effect of embolization. 2016 Vol. 23 (36): 191-193 [Abstract] ( 121 ) HTML (45 KB)  PDF  (0 KB)  ( 32 ) 194 Insulation care awakening intraoperative and postoperative stress in patients with general anesthesia LI Yi-jun ObjectiveTo explore the general anesthesia patients accepted insulation care on its awakening intraoperative and postoperative stress.Methods120 cases of patients with general anesthesia from December 2015 to August 2016 were selected and randomly divided into two groups,60 cases in each group,the control group was treated primary care,the experimental group was given insulation care,the post operative stress condition and revive the intraoperative of two groups were compared.ResultsBleeding amount of experimental group of patients was(492.36±10.30)ml,infusion volume was(2107.23±70.15)ml,operation time was(3.88±0.53)h,and bleeding amount of control group was(495.31±10.09) ml,infusion volume was(2119.52±75.10)ml,operation time was(3.93±0.46)h,there were no significant differences(P＞0.05);the low temperature,chills,agitation of experimental group were lower than those of control group(P＜0.05);experimental waking hours was(45.63±7.02)min,endotracheal intubation time was(24.03±7.01)min,PACU residence time was(49.63±12.20)min in the experimental group,significantly lower than those of control group of waking hours(76.56± 10.50)min,endotracheal intubation time(35.89±8.51)min,PACU residence time(79.85±13.46)min(P＜0.05);two groups of patients had stress response,which stress reaction of the experimental group was lower than that of control group (P＜0.05).ConclusionGeneral anesthesia patients accepted insulation care,will not affect its operation,and can shorten the postoperative fully awake time,reduce the incidence of low temperature,chills,etc.,reduce stress,so as to promote the surgical treatment better. 2016 Vol. 23 (36): 194-196 [Abstract] ( 133 ) HTML (42 KB)  PDF  (0 KB)  ( 36 )

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