PSA灰区患者术前检查与其前列腺穿刺阳性情况的相关性分析

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Abstract ObjectiveTo investigate correlation of prostate biopsy positive results and preoperative examination in prostate specific antigen (PSA)Gray area patients.Methods495 patients who underwent prostatic biopsy in the PSA gray area from March 2011 to March 2016 in Department of Urology of Central Hospital of Shuyang County and Xuzhou City Central Hospital were retrospectively studied and divided into two groups of prostatic biopsy positive group(n=150) and prostatic biopsy negative group (n=345)according to the results of prostatic biopsy.Age,smoking or not,whether hypertension,whether diabetes,MRI nodules,digital rectal examination (DRE)nodules,PSA,free PSA (FPSA),PSA density (PSAD),prostate volume between two groups were compared,and correlation of puncture positive result and preoperative examination was analyzed.ResultsThere were no significant differences between two groups in age,smoking or not, whether hypertension,whether diabetes,and FPSA,prostate volume between two groups(P=0.1078,0.6375,0.0517,0.4811, 0.1363,0.2915;all P＞0.05);There were statistically significant difference in MRI nodules,DRE nodules,PSA,PSAD(all P＜0.01).Pearson correlation analysis results showed that MRI nodules,DRE nodules,PSA,PSAD had positive correlation with transrectal prostate biopsy positive (r=0.236,0.536,0.331,0.536;all P＜0.05).Conclusion Positive rate of puncture is higher in patients of PSA gray area with higher PSA,higher PASD,MRI or DRE found nodules;age,smoking,hypertension,diabetes,FPSA have no relationship with puncture result.

Key words： Prostate specific antigen Gray area Transrectal prostate biopsy Prostate cancer

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	Articles by authors
	WANG Mei-cai
	ZHOU Rong-sheng
	ZHOU Xiang-ju
	PANG Kun
	HAN Cong-hui

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WANG Mei-cai,ZHOU Rong-sheng,ZHOU Xiang-ju, et al. Relationship of prostate biopsy positive results and preoperative examination in prostate specific antigen gray area patients[J]. 中国当代医药, 2016, 23(36): 48-50.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I36/48

[1]	Oral E，Simonsen N，Brennan C，et al.Unit nonresponse in a population-based study of prostate cancer[J].PLoS One，2016，11（12）：e0168364.
[2]	Jemal A，Bray F，Center MM，et al.Global cancer statistics[J]. CA Cancer J Clin，2011，61（2）：69-90.
[3]	Bray F，Sankila R，Ferlay J，et al.Estimates of cancer incidence and mortality in Europe in 1995[J].Eur J Cancer，2002，38（1）：99-166.
[4]	孙颖浩.我国前列腺癌的研究现状[J].中华泌尿外科杂志，2004，25（2）：77-78.
[5]	那彦群，叶章群，孙光，等.中国泌尿外科疾病诊断与治疗指南[M].北京：人民卫生出版社，2014：50.
[6]	孙娟娟，王朝夫，张慧芝，等.前列腺癌穿刺标本与对应根治标本Gleason评分符合率的研究[J].中国癌症杂志，2012，22（12）：929-933.
[7]	张海彬，胡道予，张娟.3.0T磁共振动脉自旋标记（ASL）技术诊断前列腺癌[J].放射学实践，2012，27（6）：645-651.
[8]	李鸣，那彦群.不同水平前列腺特异性抗原的前列腺癌诊断率[J].中华医学杂志，2008，88（1）：16-18.
[9]	Moul JW.Comparison of DRE and PSA in the detection of prostate cancer[J].J Urol，2017，197（2S）：S208-S209.
[10]	Zhang M，Chen L，Yuan Z，et al.Combined serum and EPS-urine proteomic analysis using iTRAQ technology for discovery of potential prostate cancer biomarkers[J].Discov Med，2016，22（122）：281-295.
[11]	Cochetti G，Poli G，Guelfi G，et al.Different levels of serum microRNAs in prostate cancer and benign prostatic hyperplasia：evaluation of potential diagnostic and prognostic role[J].Onco Targets Ther，2016，13（9）：7545-7553.
[12]	Fu AZ，Tsai HT，Haque R，et al.Mortality and androgendeprivation therapy as salvage treatment for biochemical recurrence after primary therapy for clinically localized prostate cancer[J].J Urol，2016.[Epub ahead of print].
[13]	Turner RM，Yabes JG，Woldemichael E，et al.Prognostic implications of immediate PSA response to early salvage radiotherapy[J].Can J Urol，2016，23（6）：8568-8575.
[14]	Elabbady A，Hashad MM，Kotb AF，et al.Studying the effect of type 2 diabetes mellitus on prostate-related parameters：a prospective single institutional study[J].Prostate Int，2016，4（4）：156-159.
[15]	Cabarkapa S，Perera M，McGrath S，et al.Prostate cancer screening with prostate-specific antigen：a guide to the guidelines[J].Prostate Int，2016，4（4）：125-129.