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2017 Vol. 24, No. 5
Published: 2017-02-18
 
 
4 Study on the change rule between different compatibility of ephedra-amond drugs and the concentration of effective components
YANG Li;LI Ying;WANG Qing-xian;SUN Yong-bing;LIU Wan;LI Wen-hong
Objective To discuss the change rule between the different compatibility of ephedra-almond drugs and the multicomponent content variation of ephedrine,pseudo-ephedrine and amygdalin.Methods The U6（64）uniform design table was selected to plan proportions,and a simultaneous quantitative HPLC method was used for determination of the content of ephedrine,pseudo-ephedrine and amygdalin in different compatibility of ephedra-almond drugs.Results The regression equation of ephedrine was y=212.36x+0.6658,R2=0.9995;the regression equation of pseudo-oephedrine was y=184.95x+0.7268,R2=0.9990;the regression equation of amygdalin was y=153.5x+2.4961,R2=0.9990.After compatibility of ephedra and almond,the content of ephedrine,pseudo-ephedrine and ephedrine,amygdalin and almond showed a good linear relationship with the compatibility ratio.Conclusion The method is simple,accurate and reproducible.The content of effective components of ephedra-almond drugs and dose is positive correlation,but it has no obvious correlation with compatibility proportion.
2017 Vol. 24 (5): 4-7转11 [Abstract] ( 151 ) HTML (58 KB)  PDF  (0 KB)  ( 36 )
8 The effects of Thalidomide on the proliferation,IL-6 and Cx43 expression of prostate cancer PC3 cells
YIN Wei-hua;XIA Hong-mei;LUO Xiao-jin;XU Rong;HU Xiao-xiong
Objective To observe the effects of Thalidomide on the proliferation and apoptosis of prostate cancer PC3 cells,as well as on the expression of the protein Cx43 and IL-6 in this cells.Methods Thalidomide with different concentrations (6.25,12.50,25.00,50.00,100.00 μg/ml)was added to PC3 cells at the logarithmic growth phase.MTT was used to detect the inhibitory effect of different concentration of Thalidomide on proliferation of PC3 cells,the apoptosis rate of PC3 cells was studied by Annexin V fluorescein isothiocyanate（Annexin PI）double staining with flow cytometry.Enzyme-linked Immunosorbnent assay method was used to detect the expression of IL-6 and Cx43 in PC3 cells. Results Below 25.00,50.00,100.00 μg/ml,Talidomide significantly inhibited the proliferation of PC3 cells in vitro,and the inhibition rate increased with the increase of time and concentration,the expression of IL-6 decreased with the increasing of concentration(r=-0.924，P=0.009),the expression of Cx43 had positive correlation with the concentration of thalidomide(r=0.915，P=0.010).Conclusion Thalidomide can inhibit the expression of IL-6 in PC3 cells,increase the expression levels of Cx43,restore the functional refreshment of gap junction intercellular communication function in prostate cancer PC3 cells for in inhibiting the proliferation of PC3 cells and inducing its apoptosis,in order to inhibit the growth of tumor.
2017 Vol. 24 (5): 8-11 [Abstract] ( 192 ) HTML (44 KB)  PDF  (0 KB)  ( 26 )
12 Determination Rifamycin sodium in the cerebrospinal fluid of patients with tuberculous meningitis
ZHANG Xiao-dong;YAO Fang

Objective To establish a method for determination R ifamycin sodium in the cerebrospinal fluid of patients with tuberculous meningitis by HPLC-MS/MS.Methods Column was XTerraMS C18（4.6 mm×100.0 mm,3.5 μm）.Mobile phase was Ammonium acetate (0.01 mol/L)-Methanol(10:90).Flow rate was 0.4 ml/min.Multiple reaction monitoring (MR M)was used by HPLC.Results The linear ranges of 0.4-4.0 μg/ml(r=0.9997)was better;Detection limit was 100 ng/ml. Conclusion The method is simple,rapid,accurate,and it can be used for therapeutic drug monitoring.
2017 Vol. 24 (5): 12-14 [Abstract] ( 172 ) HTML (39 KB)  PDF  (0 KB)  ( 32 )
15 Research progress on the correlation between relevant parameters of red blood cell,platelets and coronary heart disease
LI Yan;LIU Zhi-yue
Recently it has been shown that there is a close correlation between red blood cell distribution width(RDW), mean platelet volume(MPV),platelet volume distribution width(PDW)and coronary heart disease in the occurrence,development as well as prognosis.Accordingly,a new door for the clinical diagnosis and treatment can be opened by evaluating RDW,MPV and PDW as a new independent factor.The correlative study between RDW,MPV,PDW and coronary heart disease was focally discussed in this paper.
2017 Vol. 24 (5): 15-17转21 [Abstract] ( 193 ) HTML (42 KB)  PDF  (0 KB)  ( 37 )
18 Application prospect of renin inhibitor Aliskiren in the treatment of nondiabetic glomerulonephritis
WU Qiao-yuan;LIAO Yun-hua
Non-diabetic glomerulonephritis is a common cause of end stage renal disease(ESRD).The development of chronic kidney diseases(CKD)to a certain stage is through the common pathway of renal tubule interstitial fibrosis to ESRD,and renin-angiotensin-aldosterone system (RAAS)plays an important role during the process.Blocking RAAS system can delay the progress of CKD.Angiotensin-converting enzyme inhibitor(ACEI)or angiotensin receptor blocker (ARB)exerts a great role,but which still is not satisfying due to persisted proteinuria in some patients.Aliskiren is the first non-peptide direct renin inhibitor,which not only directly influences on RAAS,also blocks the PRR/MAPK/ERK signal pathway with anti-fibrosis.The paper focused on the prospect of applying Aliskiren to glomerulopathy.
2017 Vol. 24 (5): 18-21 [Abstract] ( 165 ) HTML (46 KB)  PDF  (0 KB)  ( 29 )
22 Changes of serum cystatin C in patients with rheumatoid arthritis and its significance
GAO Deng-wen;YU Shao-hui;ZHAO Dong
Objective To explore the change of serum cystatin C(CysC)in patients with rheumatoid arthritis(RA)and its clinical significance.Methods 70 patients with RA were selected as observation group and 70 cases of healthy check-up were selected as control group in People′s Hospital of Macheng City from June 2015 to September 2016. CysC and serum creatinine(SCr)in two groups were detected by using an automatic biochemical analyzer.MDRD equation 7 was used to calculate creatinine clearance(CCr).The correlation between CysC and SCr,CCr,CRP,ESR,DAS28 was assessed respectively.After application of glucocorticoid combined with DMARDs for three months in 30 patients in the observation group (DAS28≥3.2),CysC and some other parameters were again detected and analyzed.Results The Cystatin C level in the observation group was significantly higher than that of the control goup(P＜0.01),while SCr and CCr showed no significant difference between two groups(P＞0.05).In the observation group,CysC level was positively correlated with SCr,CRP,ESR,DAS28(r=0.297，P=0.014;r=0.321，P=0.008；r=0.566，P=0.000;r=0.383，P=0.000),and negatively correlated with CCr(r=-0.347,P=0.004).Compared with before treatment,the CysC,CRP,ESR,and DAS28 in active RA patients decreased significantly after treatment(P＜0.01).Conclusion In patients with RA,cystatin C may be not only an indicator of early renal impairment but also a marker of disease activity.
2017 Vol. 24 (5): 22-24 [Abstract] ( 146 ) HTML (37 KB)  PDF  (0 KB)  ( 38 )
25 Effects of supplemented Bifidobacterium and Lactobacillus acidophilus triple living bacteria preparation on intestinal flora after intestinal surgery
ZUO Ji-dong;LIU Guan-huan;YUAN Kai-tao
Objective To investigate the effect of Bifidobacterium and Lactobacillus acidophilus triple living bacteria preparation on intestinal flora after intestinal surgery.Methods Altogether 90 patients with colorectal cancer who were treated in our hospital from March 2015 to November 2016 were randomly divided into probiotics group and control group by using lots drawing according to the order of admission,with 45 cases in each group.Both groups were treated with radical resection;probiotics group accepted 7-day probiotic therapy before surgery.The postoperative recovery,distribution of intestinal flora before and after surgery,postoperative immune function indexes level were compared between two groups.Results The recovery time of bowel sound,exhaust time,eating time,defecation time and abdominal pain relief time of patients in the probiotics group was significantly lower than that in the control group,with statistically significant difference (P＜0.05);the number of bifidobacterium and lactobacillus and B/E levels of the probiotics group was significantly higher than that of the control group,the number of escherichia coli of the probiotics group was significantly lower than that of the control group,with statistically significant difference(P＜0.05).The level of IgA,IgG and CD4+/CD8+after surgery in the probiotics group was significantly higher than that in the control group,with statistically significant difference (P＜0.05).Conclusion Preoperative supplement of triple viable bacteria can effectively improve the intestinal flora and immune indexes after intestinal surgery,which shortens the recovery time of intestinal function after surgery and has high application value.
2017 Vol. 24 (5): 25-27 [Abstract] ( 171 ) HTML (43 KB)  PDF  (0 KB)  ( 35 )
28 Effect observation of Mosapride combined with colon hydrotherapy machine in the treatment of chronic functional constipation
ZHAO Lan-min;SHI Zhen-dong
Objective To explore the clinical effect and safety of Mosapride combined with colon hydrotherapy machine in the treatment of chronic functional constipation(CFC).Methods According to random number table method,106 patients with CFC in our hospital from January 2015 to June 2016 were selected and randomly divided into control group and observation group,and each group was 53 cases.Patients in the control group were treated with Mosapride 5 mg, 3 times a day,patients in the observation group were treated with colon cleansing with JCJ-1 colon hydrotherapy machine on the basis of the control group,3 times a week,both groups was treated for 4 weeks.The clinical effect,4 weeks recurrence rate and incidence rate of adverse reactions between two groups were compared respectively.Results The total effective rate of the observation group(98.1%)was obviously higher than that of the control group(73.6%),and the difference was statistically significant(P＜0.05).The 4 weeks recurrence rate of the control group(15.1%)was obviously higher than that of the observation group(3.8%),and the difference was statistically significant(P＜0.05).The incidence rate of adverse reactions in the observation group and the control group was 11.3%and 9.4%respectively,there was no significant difference between two groups(P＞0.05).Conclusion Mosapride combined with colon hydrotherapy machine in the treatment of CFC is better than simple drug treatment.It is comfort and safety,and can be widely used in clinical application.
2017 Vol. 24 (5): 28-30 [Abstract] ( 167 ) HTML (41 KB)  PDF  (0 KB)  ( 33 )
31 Analysis on the effect of BiPAP intermittent ventilation combined with Naloxone in the treatment of acute exacerbation of chronic obstructive pulmonary disease complicated with respiratory failure
LIN Nong-wei
Objective To investigate the effect of BiPAP intermittent ventilation combined with Naloxone in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)complicated with respiratory failure. Methods 46 patients with AECOPD complicated with respiratory failure who were hospitalized in our hospital from January 2012 to December 2014 were selected and randomly divided into the BiPAP ventilation group and the control group,23 cases in each group.The control group was given conventional oxygen therapy,anti-infection,antispasmodic,and symptomatic treatment,if necessary,the control group was given mechanical ventilation treatment.The BiPAP ventilation group was treated with intermittent ventilation by BiPAP non-invasive ventilator combined with Naloxone on the basis of the conventional oxygen therapy,anti-infection,antispasmodic,and symptomatic treatment.Changes in arterial blood gas analysis and changes in 6-minute walking distance before and after treatment were observed between the two groups.Results The level of PaO2in the two groups after treatment was higher than that before treatment,and the level of PaCO2in the two groups after treatment was lower than that before treatment,with significant difference(P＜0.05).The level of PaO2in the BiPAP ventilation group after treatment was higher than that in the control group,and the level of PaCO2in the BiPAP ventilation group after treatment was lower than that in the control group,with significant difference (P＜0.05).6-minute walking distance after treatment in the two groups was longer than that before treatment,with significant difference(P＜0.05).6-minute walking distance in the BiPAP ventilation group after treatment was longer than that in the control group,with significant difference (P＜0.05).There was no need for endotracheal intubation and mechanical ventilation in the BiPAP ventilation group.Conclusion BiPAP intermittent ventilation combined with Naloxone is effective in the treatment of patients with AECOPD complicated with respiratory failure and has no adverse reactions.
2017 Vol. 24 (5): 31-33 [Abstract] ( 164 ) HTML (41 KB)  PDF  (0 KB)  ( 29 )
34 The clinical research of transoral and open thyroidectomy for innocent thyroid nodule disease
CHEN Xiao-ying;HAN Hong-bin;CHEN Qiang;SUN Hong-ge;WANG Yu-xiang;YAN Dang
Objective To investigate the clinical effect of transoral and conventional open thyroidectomy to treat benign thyroid disease.Methods 62 patients with benign thyroid disease in our hospital from November 2013 to August 2015 were selected and were divided into the observation group and the control group by the patients willing.The observation group was included 25 patients and were received thrnsoral access for thyroidectomy,the control group was included 37 patients and had conventional open thyroidectomy.The operation time,postoperative drainage,hospital stay time,postoperative complications and cosmetic satisfactory were compared.Results 25 patients were successfully completed transoral thyroidectomy,without any perioperative complications.The intraoperative blood loss of observation group was(25±5)ml and hospitalization time was(4.4±0.6)days;the intraoperative blood loss of control group was(35±5)ml and hospitalization time was(6.6±0.7)days,with siginifiant difference（P＜0.05）,the operation time,the first day drainage after operation, the rate of postoperative recurrence and the feeling about pharyngeal swallowing after 6 months were no siginifiant differences(P＞0.05).Conclusion Transoral thyroidectomy can be perfomed in patients with begnign thyroid lesions with cosmetic incision,recoveryfaster,safe and reliable compared to convential open thyroidectomy.
2017 Vol. 24 (5): 34-36 [Abstract] ( 148 ) HTML (38 KB)  PDF  (0 KB)  ( 30 )
37 Effectiveness and safety study of initiating basal insulin therapy in type 2 diabetes mellitus
XU Ding-bo
Objective To explore the efficacy and safety of basal insulin therapy in combiantion in type 2 diabetes mellitus patients who took hypoglycemic agents orally and didn′t obtain a favorable effect.Methods From January 2013 to June 2015,100 patients with T2DM from outpatient clinics and inpatient departments in unsatisfied effect when oral administration of hypoglycemic agents in our hospital were selected and they were asked to add basal insulin therapy besides oral administration of hypoglycemic agents.According to different types of basal insulin,they were divided into neutral protamine hagedorn(NPH)insulin group(n=33),insulin glargine group(n=34)and insulin detemir group(n=33). The indexes of FPG,2 h PG,HbA1c,BMI,occurrence of hypoglycemia,and quality of life among three groups before and after therapy were compared.Results After treatment,the levels of FPG,2 h PG and HbA1c were significantly decreased than before treatment(P＜0.01).The BMI in the NPH insulin group was increased compared with that before treatment (P＜0.05),while BMI in the insulin glargine group and insulin detemir group were compared before treatment,with no statisticant difference (P＞0.05).Compared with the NPH insulin group,occurrence of hypoglycemia in the insulin glargine group and insulin detemir group was much lower (P＜0.05).The scores of EQ-5D after therapy in the three groups were remarkably increased compared with those before treatment(P＜0.05).Conclusion For T2DM patients who take hypoglycemic agents orally without a great effect,initiation of basal insulin in time is safe and effective,which is better by long-acting insulin analogues in effectiveness and safety.
2017 Vol. 24 (5): 37-39 [Abstract] ( 190 ) HTML (38 KB)  PDF  (0 KB)  ( 29 )
40 Effect evaluation of diabetes health education in community residents of Zhongshan City
WANG Rong-zeng
Objective To explore method of the health education of diabetes patients in community of Zhongshan City and evaluate its the effect.Methods 94 diabetic patients in Henglan Community of Zhongshan City were selected as research object from October 2014 to October 2015 and randomly divided into observation group and control group by using computer software for grouping,47 cases in each group.The observation group was given community health education intervention,the control group was treated with conventional education intervention activities.The effects of two groups were compared.Results After intervention,the awareness of diabetes prevention and treatment knowledge in the observation group was significantly improved than that before intervention(P＜0.05);only the awareness of diabetes prevention was improved significantly in the control group (P＜0.05),and the rest of the contents were not significantly improved(P＞0.05).Before intervention,the difference in the awareness of diabetes prevention and treatment knowledge between two groups had no statistical significance (P＞0.05);after intervention,the awareness of diabetes prevention knowledge in the observation group was significantly higher than that in the control group respectively,and the difference was statistically significant(P＜0.05).Health examination rate of within 1 year of intervention,blood sugar test rate of within 1 year of intervention and blood pressure measurement rate of within 1 year of intervention in the observation group was significantly higher than that before intervention (P＜0.05),the rate of smoking and bad mood rate was not significantly improved (P＞0.05)before and after intervention.Before intervention,there was no statistically significant difference in diabetes related behavior between two groups(P＞0.05);health examination rate of within 1 year of intervention,blood sugar test rate of within 1 year of intervention and blood pressure measurement rate of within 1 year of intervention in the observation group was significantly higher than that in the control group (46.81%vs.23.40%;34.04%vs.17.02%; 78.72%vs.48.94%)(P＜0.05).Conclusion The formation of diabetes community health education intervention can effectively improve the community residents′awareness of diabetes knowledge and good health behaviors,it is of great clinical significance to strengthen the health education of diabetes in community.
2017 Vol. 24 (5): 40-42转47 [Abstract] ( 149 ) HTML (41 KB)  PDF  (0 KB)  ( 34 )
43 Clinical effect of endoscopic mucosal resection by injection method in the treatment of laterally spreading tumor
ZHI Zhong-jing;CHEN Mu-wei;LYU Jian-guang;SHAO Shao-wei;TA Shi-nian;TAN Fei-ou
Objective To evaluate the clinical effect of endoscopic mucosal resection (EMR)by injection method in the treatment of colorectal laterally spreading tumor(LST).Methods 32 patients with LST treated with EMR from July 2014 to December 2015 in our hospital were selected as the EMR group,all the specimens were treated with standardized methods,and the whole tumor was evaluated.90 patients with LST treated by conventional electrocoagulation,argon ion coagulation and surgical operation in our hospital from July 2010 to July 2014 were selected as the conventional treatment group.Patients of the two groups were followed up at 3,6 months and 12 months after operation,and the efficacy and safety of EMR were evaluated.Results All patients were successfully treated and followed up,all 32 patients of the EMR group received complete pathological specimens,and the pathological results showed that 18 cases of tubular adenoma,9 cases of villous tubular adenoma,3 cases of villi tumor,and 2 cases of mucinous carcinoma.Among the 2 cases of mucinous carcinoma,1 case of the postoperative pathological specimen showed lesion-free residual tumor at 2 mm margin;additional surgery was not needed;another 1 case showed residual tumor,with additional surgery;the complete resection rate was 96.9%.No intraoperative perforation was observed.Hemorrhage occurred in all 3 patients,and the microscopic hemostasis was successful.Among patients of the conventional treatment group,only 15 cases received complete specimens,which were all surgical cases,showing adenoma.Among them,10 cases were tubular adenoma,3cases were villous tubular adenoma,and 4 cases were villi tumor;bleeding was shown in 2 patients receiving surgery.Intraoperative hemostasis was successful in both patients,and the secondary open surgery was not needed.The recurrence rates at 3 months after the surgery of the EMR group and conventional treatment group (0.00%vs.3.33%)had no statistically significant difference (P＞0.05),while recurrence rates at 6,12 months after the surgery (6.25%vs.28.90%, 9.40%vs.37.80%)had statistically significant difference(P＜0.01).Conclusion EMR can treat most of the patients with LST observed clinical microscopic.Compared with the traditional treatment,it has the advantages of exact curative effect, less traumatic,low recurrence rate,complete specimens and other advantages,which is worthy of clinical promotion.
2017 Vol. 24 (5): 43-47 [Abstract] ( 163 ) HTML (51 KB)  PDF  (0 KB)  ( 33 )
48 Application of high risk type HPV-DNA detection combined with TCT in the health survey of women′s health at the basic level
CHEN Wan;WANG Jin-ying;LIN fei;CHEN Shu-yin
Objective To explore the application effect of high risk type HPV-DNA detection combined with TCT detection in cervical cancer screening of cervical cancer in women of the basic level.Methods 860 women of the administrative region in various organs and institutions organization for regular health examination in our hospital from March 2015 to December 2016 were selected as the research object,high risk type HPV-DNA and TCT were used to detect the early stage of cervical cancer.Results The positive rate of TCT was 4.77%(41/860),the positive rate of HPV was 2.09% (18/860),the positive rate of combined detection was 5.35% (46/860).The detection sensitivity of TCT,HPV and combined detection of TCT and HPV were 89.13%,39.13%,100.00%,respectively.Conclusion High risk type HPV-DNA detection combined with TCT has a higher positive detection rate and sensitivity in the screening of cervical cancer lesions in women at the basic level,and it can be widely used in cervical cancer screening.
2017 Vol. 24 (5): 48-50 [Abstract] ( 192 ) HTML (38 KB)  PDF  (0 KB)  ( 36 )
51 Effect observation of CT guided125I particle implantation combined with bronchial artery infusion chemotherapy and embolization in the treatment of advanced non-small cell lung cancer
LIN Hui;SU Xiang-hua
Objective To explore the clinical efficacy and safety of CT guided125I particle implantation combined with bronchial artery infusion chemotherapy and embolization in the treatment of advanced non-small cell lung cancer. Methods Altogether 70 cases ofⅢb-Ⅳstage non-small cell lung cancer who were treated in Department of Respiration in our hospital from May 2012 to May 2014 were selected and divided into the experiment group (34 cases)and the control group(36 cases)according to the different treatment methods.The experiment group was treated with CT125I guided particle implantation combined with bronchial artery infusion chemotherapy and embolization,and the control group was treated with bronchial artery infusion chemotherapy and embolization.For all the patients,Gemcitabine combined with Cisplatin chemotherapy was taken as the chemotherapy protocol and CT examinations and follow-up at postoperative 1,3 and 6 months were made for observation of the total effective rate and the incidence rate of adverse reactions.Results The near-term total effective rate of the experimental group was 76.47%,which was higher than that of the control group(50.00%),with significant difference(P＜0.05).The incidence rate of pneumothorax,hemoptysis,chest pain in the experimental group was higher than that in the control group,with significant difference(P＜0.05).There was no significant difference between the two groups in the incidence rate of fever and bone marrow suppression (P＞0.05). All adverse reactions were light and could be controlled.Conclusion As a safe and minimally-invasive method,application of125I particle implantation combined with bronchial artery infusion chemotherapy and embolization has significant near-term effect in the treatment of advanced non-small cell lung cancers.
2017 Vol. 24 (5): 51-54 [Abstract] ( 177 ) HTML (46 KB)  PDF  (0 KB)  ( 25 )
55 Clinical effect and safety observation of thoracoscopy and laparoscopy combined with surgery in the treatment of elderly patients with esophageal cancer
SU Wen-jie
Objective To investigate the short-term efficacy and safety of thoracoscopy and laparoscopy combined with surgery in the treatment of elderly patients with esophageal cancer.Methods 76 elderly patients with esophageal cancer treated in our hospital from January 2015 to April 2016 were selected as the research object and were randomly divided into the observation group and the control group,38 cases in each group.Patients in the control group were treated with conventional open thoracic esophageal cancer radical surgery while patients in the observation group were treated with thoracic laparoscopic surgery combined with esophageal cancer radical surgery.The condition of operation,complications and prognosis of the two groups were compared.Results There were no significant differences in the number of lymph node dissection and operation time between the two groups(P＞0.05).The amount of intraoperative bleeding in the observation group was less than that in the control group,and the extubation time in the observation group was shorter than that in the control group,with significant differences(P＜0.01).The incidence rate of complication in the observation group after operation was 13.16%,which was lower than that in the control group(28.95%),with significant difference(P＜0.05).The postoperative lymph node metastasis rate,reoperation rate,postoperative 6 and 9 months cumulative mortality rate were 5.26%,2.63%,2.63%,5.26%in the observation group,compared with the control group (2.63%,0.00%,0.00%, 2.63%),the differences were not statistically significant(P＞0.05).Conclusion The effect of the application of thoracoscopy and laparoscopy combined with surgery in the treatment of elderly patients with esophageal cancer is definite and the wound is small and the incidence of postoperative complications is low with good prognosis,it is worth promoting.
2017 Vol. 24 (5): 55-57 [Abstract] ( 165 ) HTML (38 KB)  PDF  (0 KB)  ( 36 )
58 Clinical effect analysis of Embosphere microspheres embolization in the treatment of liver metastases from colon cancer
ZHANG Meng;GAO Zhong
Objective To explore the clinical effect of Embosphere microspheres embolization in the treatment of liver metastases from colon cancer.Methods The clinical data and efficacy of 40 patients with liver metastases from colon cancer(the study group)from October 2014 to August 2016 in our hospital were retrospectively analyzed and compared with the 55 cases of liver metastasis of colon cancer patients accepted lipiodol treatment with the same period(the control group)in our hospital.The incidence rate of adverse reactions and the short-term efficacy of the two groups were compared.Results The disease remission rate and the disease control rate in the study group was higher than that in the control group,with significant difference (P＜0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P＞0.05).Conclusion Short term efficacy of Embosphere microspheres embolization in the treatment of liver metastases from colorectal cancer is accurate,it has good clinical application value.
2017 Vol. 24 (5): 58-60 [Abstract] ( 205 ) HTML (35 KB)  PDF  (0 KB)  ( 27 )
61 Clinical analysis of adverse effect of intrahepatic cholestasis of pregnancy on maternal and neonatal outcomes
PAN Fang-li;LIANG Quan-fang;ZHOU Yin-yan
Objective To explore the effect of intrahepatic cholestasis of pregnancy (ICP)on maternal and neonatal outcomes.Methods 65 patients with ICP from January 2008 to December 2015 treated in our hospital were selected as study group,and they were divided into mild group (43 cases)and severe group (22 cases)according to the level of serum total bile acid;71 healthy parturient from our hospital at the same period were selected as control group.The difference of maternal and infant outcome between two groups were observed.Results Incidence of premature,meconium stained amniotic fluid,cesarean section and postpartum hemorrhage in study group was obvious higher than that in the control group respectively,the difference was statistically significant(P＜0.05);the incidence of premature rupture of membranes in the two groups had no significant difference(P＞0.05);the incidence of low birth weight infants,fetal distress and neonatal asphyxia of the study group was compared with the control group,and the difference was statistically significant(P＜0.05).Incidence of premature,meconium stained amniotic fluid,low birth weight infants,fetal distress and neonatal asphyxia in severe group was higher than that in mild group respectively(P＜0.05),the incidence of premature rupture of membranes,cesarean section,and postpartum hemorrhage had no significant difference between two groups (P＞0.05).Conclusion Intrahepatic cholestasis of pregnancy is an important cause of adverse maternal and neonatal outcomes,nursing staff should strengthen prenatal care for maternal and perinatal fetal care.Early detection,prevention and treatment should be done for intrahepatic cholestasis of pregnancy.
2017 Vol. 24 (5): 61-63 [Abstract] ( 170 ) HTML (38 KB)  PDF  (0 KB)  ( 34 )
64 Clinical study of NovaSure endometrial ablation and transcervical resection of endometrium in the treatment of abnormal uterine bleeding
HUANG Xia
Objective To compare the clinical efficacy of NovaSure endometrial resection and transcervical resection of endometrium in the treatment of abnormal uterine bleeding.Methods A total of 80 patients with abnormal uterine bleeding in our hospital from December 2015 to September 2016 was selected and randomly divided into observation group and control group,40 cases in each group.The observation group was given the NovaSure endometrial resection,while the control group was given the transcervical resection of endometrium under hysteroscope.The efficient and incidence of postoperative complications of two groups were observed.Results The efficient in the two groups had no statistically significant difference (P＞0.05);the incidence of abdominal pain,fever postoperative of the control group was higher than that of the observation group,and the total incidence of postoperative complications between the two groups had statistically significant difference(P＜0.05).Conclusion Both the NovaSure endometrial ablation and ranscervical resection of endometrium for the treatment of abnormal uterine bleeding have certain effect,but the NovaSure endometrial resection with lower incidence of complications and more safety,so it is worthy of clinical application.
2017 Vol. 24 (5): 64-66 [Abstract] ( 180 ) HTML (38 KB)  PDF  (0 KB)  ( 32 )
67 The feasibility of laparoscopic hysterectomy and bilateral fallopian tube removal and its effect on ovarian function and perimenopausal symptoms
WANG Xing
Objective To investigate the feasibility of laparoscopic hysterectomy and bilateral fallopian tube removal and its effect on ovarian function and perimenopausal symptoms.Methods Ninety patients with benign uterine diseases in our hospital from January to December 2014 were selected and divided into observation group (45 cases)and control group(45 cases)according to their wish.The control group was treated with laparoscopic hysterectomy and bilateral fallopian tube reservation,the observation group was treated with laparoscopic hysterectomy and bilateral fallopian tube removal.Ovarian function related indicators and the incidence of perimenopausal symptoms between two groups were compared.Results Compared with before treatment,levels of serum estradiol decreased after treatment in the two groups, and levels of FSH and LH elevated,the differences were statistically significant(P＜0.05);the above index had no significant difference between the two groups at 1 week and 3 months after operation (P＞0.05);the incidence of perimenopausal symptoms in the control group before operation,1 week after operation,3 months after operation was 20.00%,28.89%and 40.00%respectively,which was 24.44%,33.33%and 42.22%respectively in observation group,and the difference between two groups was not statistically significant(P＞0.05).Conclusion Laparoscopic total hysterectomy and bilateral fallopian tube removal has good safety,and it is worthy of clinical application.
2017 Vol. 24 (5): 67-69 [Abstract] ( 183 ) HTML (37 KB)  PDF  (0 KB)  ( 33 )
70 Application effect of painless labor in obstetric delivery
HUANG Ying-hong
Objective To study and discuss the application effect of painless labor in obstetric delivery.Methods Fifty delivery maternal from January 2015 to November 2016 in the Department of Obstetrics of our hospital were selected as the research objects,they were divided into the control group(n=24)and the observation group(n=26)according to the time of admission.The control group was received traditional maternal childbirth,the observation group was given painless childbirth technology in the course of childbirth.The labor time,cesarean section rate,postpartum hemorrhage and neonatal asphyxia were compared between two groups.Results Compared with the control group,the labor time of the observation group was significantly shortened(P＜0.05).The rate of cesarean section with social factors and total cesarean section of maternal in the observation group was significantly lower than the control group (P＜0.05);there was no significant difference of maternal cesarean section rate with medical factors between two groups(P＞0.05).The postpartum rate and amount of 24 h postpartum hemorrhage bleeding of maternal in the observation group was significantly lower than the control group(P＜0.05);the rate of neonatal asphyxia in the observation group was significantly lower than the control group(P＜0.05).Conclusion The application of painless childbirth technology in obstetric delivery can effectively reduce the rate of cesarean section and postpartum hemorrhage and neonatal asphyxia,improve maternal and neonatal outcomes.
2017 Vol. 24 (5): 70-72 [Abstract] ( 207 ) HTML (40 KB)  PDF  (0 KB)  ( 47 )
73 Application of unprotected perineum delivery combined with continuous epidural analgesia in primipara
LAN Hua-chun
Objective To study the clinical value of unprotected perineum delivery combined with continuous epidural analgesia in primipara.Methods 80 primiparous women undergoing transvaginal delivery from December 2015 to November 2016 were enrolled in this study,and they were divided into control group and observation group by the random number table method,40 cases in each group.The control group was underwent vaginal delivery and unprotected perineum delivery,and the observation group was treated with continuous epidural analgesia on the basis of the treatment of the control group.Then the pain degree at different time point,the time of restoring sexual life,sexual arousal time and sex once a month were compared between the two groups,and the perineal laceration during the delivery of the two groups was counted.Results In the second stage of labor,24 h after delivery and at the time of discharge,the pain visual analogue scores in the observation group was significantly lower than that of the control group (P＜0.01);the time of restoring normal sexual life in the observation group was significantly earlier than that of the control group (P＜0.01); the time of sexual arousal was significantly faster than that of the control group (P＜0.01);regularity of sexual activity was significantly higher than the control group(P＜0.01).Conclusion Unprotected perineum delivery combined with continuous epidural analgesia can effectively reduce pain during maternity labor and reduce perineal laceration and lateral rate,so it can improve postoperative life quality.
2017 Vol. 24 (5): 73-75 [Abstract] ( 183 ) HTML (40 KB)  PDF  (0 KB)  ( 34 )
76 Impact of the second birth course on pelvic floor muscle strength of puerpera after natural labor
HE Chun-xia
Objective To explore the impact of the second birth course on pelvic floor muscle strength of puerpera after natural labor.Methods 200 puerperas from March 2014 to May 2016 in People′s Hospital of Lingyun County were divided into control group(the second birth course≤2 h,99 cases)and observation group(the second stage of labor more than 2 h and less than 3 h,101 cases).French PHENIX USB 4 pelvic floor muscle stimulator was used to detected pelvic muscle strength of puerperal in two groups 6-8 weeks after delivery.Results After delivery,the incidence of typeⅠmuscle fiber injury of observation group was 77.22%,was higher than that of the control group (57.57%),the difference was statistically significant(P＜0.01);the incidence of typeⅡmuscle fiber injury of the observation group was 42.57%, was slightly higher than that of the control group(41.41%),but the difference was not statistically significant(P＞0.05). The fatigue of typeⅠandⅡmuscle fiber in the observation group was(9.3±0.8)%and (3.2±0.6)%respectively,was higher than that in the control group [(4.3±0.5)%,(2.6±0.4)%],the difference was statistically significant(P＜0.01).The vaginal pressure of typeⅠandⅡmuscle fiber in the observation group was(62.4±7.4),(79.3±2.5)cmH2O respectively, was lower than that in the control group [(81.5±8.6),(92.3±1.2)cmH2O],the difference was statistically significant(P＜0.01).Conclusion The extension of the second stage of labor has more damage on pelvic muscle strength,and timely inspection and prevention should be done for puerperal.
2017 Vol. 24 (5): 76-78 [Abstract] ( 177 ) HTML (37 KB)  PDF  (0 KB)  ( 43 )
79 Analysis of the effect of orthodontic orthognathic in the treatment of adult patients with skeletal classⅢmalocclusion
XIE Yue-ling
Objective To discuss the effect of orthodontic orthognathic in the treatment of adult patients with skeletal classⅢ malocclusion.Methods Clinical data of 31 cases with skeletal classⅢ malocclusion treated with orthodontic combined and orthognathic treatment from January 2013 to December 2015 in our hospital were ranalyzed.Changes of measurement indexes of hard tissue and soft tissue after treatment were compared.Results Indexes of hard tissue of SNA,SNB,ANB,U1-NA,L1-NB,U1-L1,NP-FH,NA-PA,Wits,FMA,FMIA,MPA,NS-Me,ANS-Me/N-Me,overjet and overbite after treatment was better than that before treatment,with significant difference (P＜0.05).Indexes of soft tissue of FCA,NLA,ULP,LLP,EP-UL and EP-LL after treatment was better than that before treatment,with significant difference (P＜0.05).Conclusion Orthodontic combined and orthognathic for adult patients with skeletal classⅢ malocclusion shows good eifficacy.
2017 Vol. 24 (5): 79-81 [Abstract] ( 182 ) HTML (39 KB)  PDF  (0 KB)  ( 35 )
82 Effect of combination of personalized all-ceramic abutment and all-ceramic crown restoration in anterior dental implant restoration
LI Rui;LI Peng
Objective To explore the esthetic effect of combination of personalized all-ceramic abutment and all-ceramic crowns restoration in the anterior dental implant restoration.Methods Altogether 72 cases of patients with anterior teeth loss(a total of 80 implants were placed)who were treated in our hospital from January 2014 to January 2016 were involved as the object of this research and divided into the observation group(37 cases,40 pieces)and the control group (35 cases,40 pieces)according to their selection after informed consent.The observation group was given combination of personalized all-ceramic abutment and all-ceramic crowns restoration,the control group was given personalized titanium abutment conbined with all-ceramic crowns restoration.The gingival index,plaque index and pink esthetic score(PES) at postoperative 1 week,3 months and 6 months of the two groups were compared.Results The gingival index and plaque index of the observation group at 3 and 6 months after operation was higher than that of the control group,with significant difference (P＜0.05).The satisfaction degree of the observation group at 3 and 6 months after operation was higher than that of the control group,with significant difference(P＜0.05).Conclusion In contrast with the titanium abutment,the personalized all-ceramic abutment achieves more significant clinical effect in dental restoration,which is more suitable for patients.
2017 Vol. 24 (5): 82-84 [Abstract] ( 171 ) HTML (36 KB)  PDF  (0 KB)  ( 43 )
85 Study on the clinical effect and feasibility of one-time root canal therapy in the treatment of pulpitis
LI Li
Objective To investigate the clinical effect and feasibility of one-time root canal therapy in the treatment of pulpitis.Methods 240 patients with pulpitis from January 2014 to July 2015 in our hospital were selected as the research objects.According to the average distribution principle,all the patients were divided into the observation group and the control group,120 cases in each group.The observation group was given one-time root canal therapy,and the control group was treated with traditional root canal therapy.The degree of postoperative pain was observed and recorded.The short-term and long-term clinical results of the two groups after 2 weeks and 12 months of follow-up were compared,respectively.Results The postoperative pain of the observation group was lower than that of the control group,with significant difference(P＜0.01).The short-term total effective rate of the observation group was 91.67%,which was higher than that of the control group(77.50%),with significant difference(P＜0.01).The long-term total effective rate of the observation group was 93.33%,which was higher than that of the control group (81.67%),with significant difference (P＜0.01).Conclusion By comparing with the traditional root canal treatment,one-time root canal treatment can significantly relieve postoperative pain and improve the curative effects of short-term and long-term clinical treatment,it is worthy of popularization and application.
2017 Vol. 24 (5): 85-86转92 [Abstract] ( 133 ) HTML (36 KB)  PDF  (0 KB)  ( 32 )
87 Effect of Montelukast Sodium Tablets combined with Budesonide Nasal Spray in treating allergic rhinitis
ZHANG Yan
Objective To explore the effect of Montelukast Sodium Tablets combined with Budesonide Nasal Spray in treating allergic rhinitis.Methods 150 allergic rhinitis patients from January 2014 to December 2015 in our hospital were selected and randomly divided into the observation group and the control group,and each group was 75 cases.The control group was only used Budesonide Nasal Spray,and the observation group was used Montelukast Sodium Tablets combined with Budesonide Nasal Spray.The RQLQ score and the serum index level of IL-6,IL-8, IL-10 in the two groups were compared.Results The score of seven dimensions of the RQLQ scale in the observation group was lower than that in the control group,with significant difference(P＜0.05).The levels of IL-6 and IL-8 in the observation group was lower than that in the control group,and the level of IL-10 in the observation group was higher than that in the control group,with significant difference (P＜0.05).Conclusion Montelukast Sodium Tablets combined with Budesonide Nasal Spray can effectively improve the quality life of patients with allergic rhinitis,and reduce the related serum levels.
2017 Vol. 24 (5): 87-89 [Abstract] ( 175 ) HTML (38 KB)  PDF  (0 KB)  ( 28 )
90 Effect of self-etching adhesive on microleakage after sealing resin-filled body
CHEN Xiao-xia;CHANG Jie;WANG Yan-song
Objective To investigate the effect of self-etching adhesive on microleakage after sealing of resin-filled body.Methods Sixty fresh bicuspid in vitro in our hospital from February 2015 to March 2016 were collected and divided into two groups according to the different adhesive,30 teeth in each group.The observation group was treated with self-etching adhesive,while the control group was given nano-full-etching adhesive,microleakage after sealing resinfilled body and tooth cavity depth between two groups were compared.Results There was significant difference(P＜0.05) in the depth of dye penetration into the tooth cavity [(0.45±0.12)mm]in the observation group and that in the control group[(1.16±0.24)mm].The edge of the resin filling post-microleakage in the observation group was significantly better than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Self-etching adhesive has the advantages of simple operation and good effect.It can effectively reduce the penetration depth of dyed tooth and improve the microleakage grade.It is the first choice of microleakage after resin sealing,worthy of further promotion and application.
2017 Vol. 24 (5): 90-92 [Abstract] ( 145 ) HTML (33 KB)  PDF  (0 KB)  ( 37 )
93 Clinical analysis of triple operation in the treatment of senile cataract with acute angle closure glaucoma
HUANG Yan;YE Mu-rong
Objective To investigate the clinical effects of triple operation(phacoemulsification with intraocular lens implantation and trabeculectomy)in the treatment of senile cataract with acute angle closure glaucoma.Methods 42 patients suffered from senile cataract with acute angle closure glaucoma in our hospital from September 2014 to May 2016 were selected and treated with triple operation.The eyesight,intraocular pressure,vision depth of central anterior chamber and complication were compared before and after operation.Results The visual acuity of 15 patients were≥0.50 and 23 patients were 0.12～0.40 6 months after operation,which significantly improved compared to with that before operation (P＜0.05).The mean intraocular pressure of 6 months after operation was(14.02±8.32)mmHg,which was statistically significantly lower than the[(36.21±7.14)mmHg]before operation(P＜0.05).The mean anterior chamber depth was(1.82± 1.06)mm before operation,with (3.52±0.61)mm 6 months after operation,and the difference was statistically significant (P＜0.05).There were no severe complications following the operation,except that intraoperative and postoperative complications included corneal edema,transient intraocular pressure and anterior chamber hemorrhage.Conclusion Triple operation in the treatment of senile cataract with acute angle closure glaucoma has the advantages of less trauma,faster visual recovery,less postoperative complications,and is worthy of clinical application.
2017 Vol. 24 (5): 93-95 [Abstract] ( 143 ) HTML (40 KB)  PDF  (0 KB)  ( 40 )
96 Clinical observation of carved porcelain farce ceramic onlay in repairing tooth defect after root canal therapy
LI Zhen;2SUN Ke-qin
Objective To observe the clinical effect of glass ceramic onlay created with carved porcelain farce(CEREC) system in repairing tooth defect after root canal therapy (RCT),to provide referance for clinic.Methods 70 teeth of 62 cases of patients,who visited to Department of General of Shanxi Medical University from April 2015 to March 2016, were repaired by glass ceramic onlay by using CEREC system after perfect RCT.In 3,6,12 months of follow-up after repairing,clinical use of teeth were understood and the quality of fixed restorations was evaluated by the United States Public Health Service(USPHS)modified standards.Results One case was out of contact,other 61 patients(69 teeth)returned on time,3-15 months of follow-up,follow-up rate was 98.39%(61/62).The prosthesis of 1 case(1 affected tooth: left lower the second molar)of follow-up cases 3 months after restoration falled off,the rest of the patients with the clinical usage of restoration were relatively satisfied,satisfaction rate of patients was 98.36%(60/61).The prosthesis of 1 tooth falled off 3 months after restoration,the others for 68 teeth were all graded A and B,success rate of restoration was 98.55%(68/69).Conclusion Clinical effect of glass ceramic onlay by using CEREC system repairing tooth defect after RCT is significant.It is deserving of clinical popularity and application.
2017 Vol. 24 (5): 96-99 [Abstract] ( 151 ) HTML (45 KB)  PDF  (0 KB)  ( 33 )
100 Retrospective analysis of 173 cases of maxillofacial fracture in Yecheng County
CHU Xiao-yang;YUAN Xiao-lin;WANG Jiang-shuan
Objective To analyze the age distribution and cause of injury in patients with maxillofacial fracture,and to understand the epidemiological characteristics of maxillofacial fracture.Methods 173 patients with maxillofacial fracture admitted into our department from January 2005 to December 2014 were analyzed statistically.Results The ratio of male to female was 5.92∶1,and the age group of 20-29 years old(34.68%)was the most commonly seen age group.Traffic accidents accounted for 46.24%.The incidence rate of mandibular fracture was the highest,and it accounted for 67.05%.The visiting time was late and people visited within 24 hours accounted for 42.20%.Internal rigid fixation technology accounted for 30.64%.Conclusion The patients with maxillofacial fracture in this area are more common in young males;traffic accident ranks in the first place;the incidence rate of mandible fracture is the highest in maxillofacial fracture and patients fail to get diagnosed timely;internal rigid fixation technology is not applied commonly.
2017 Vol. 24 (5): 100-102 [Abstract] ( 142 ) HTML (40 KB)  PDF  (0 KB)  ( 28 )
103 Clinical effect of orthodontic combined with orthognathic therapy in treatment of bony dental maxillofacial deformity
AN Ying-jie;ZHANG Hui;QI Xiao-yu
Objective To analyze the clinical effect of orthodontic combined with orthognathic therapy in treatment of bony dental maxillofacial deformity.Methods 60 cases with bony dental maxillofacial deformity treated in our hospital from January 2015 to March 2016 were selected as the study objects.All patients were treated with the orthodontic combined with orthognathic therapy.And the clinical effect was analyzed.Results SNA,SNB,ANB,OVERBITE and OVERJET indexes were significantly different in comparison with before treatment(P＜0.05).Additionally,treatment satisfaction degree was 95.00%,and the incidence rate of complication was 5.00%.Conclusion Orthodontic combined with orthognathic therapy in treatment of bony dental maxillofacial deformity achieves good clinical effect,and it cam significantly improve the relationship between appearance and occlusion and treatment satisfaction degree is high,and incidence rate of complication is low.It is worthy of promotion and application.
2017 Vol. 24 (5): 103-105 [Abstract] ( 150 ) HTML (39 KB)  PDF  (0 KB)  ( 23 )
106 Clinical effect analysis of traumatic luxated teeth in children treated by orthodontic treatment
HU Yi-peng;YANG Yun-fei;XIE Hao
Objective To explore the clinical effect of orthodontic therapy on traumatic luxated teeth in children.Methods From August 2013 to February 2014,74 children with traumatic luxated teeth diagnosed and treated in our hospital were selected as research objects.According to different therapeutic methods,they were evenly divided into treatment group(orthodontic therapy,n=37)and control group(manual reposition combining with dental arch bar splint fixation, n=37).The therapeutic effect and satisfaction on the therapeutic outcomes were compared in two groups.Results The total therapeutic effective rates in the treatment group and control group was 94.6%and 73.0%respectively,which were displayed statistical differences(P＜0.05).Among all these participants,72 ones were in good recovery without loose teeth or percussion pain.The periodontium was healthy and there was no obvious gingival recession or recession in alveolar bone.There was one case occurred with mild recession of periodontium and another one with mild loose teeth.Conclusion In the treatment of traumatic luxated teeth in children,orthodontic therapy can obtain a definite clinical effect.It can effectively correct and fix the involved teeth,restore the masticatory function,and increase the therapeutic satisfaction by pediatric patients,which can be considered as the preferred treatment for traumatic luxated teeth in children.
2017 Vol. 24 (5): 106-108 [Abstract] ( 135 ) HTML (37 KB)  PDF  (0 KB)  ( 39 )
109 Study on the clinical effect of application of implantation repair therapy in treatment of chronic periodontitis with dentition defect
HUANG Zhi-chang
Objective To explore the effect of application of implantation repair therapy in the treatment of chronic periodontitis with dentition defect.Methods Altogether 50 chronic periodontitis patients with dentition defect who were treated from January to December 2015 were selected as observation group,and then 50 cases of periodontal healthy people who received dental implant in the same period were selected as control group.The pre-operative and post-operative changes in probing depth and gingival index of observation group were analyzed,and the success rate and alveolar resorption of the two groups were compared.Results The study found that pre-operative and post-operative probing depth of observation group had significant difference(P＜0.05);but no significant difference was seen between pre-and post-operative gingival index of observation group(P＞0.05).The implant retention rate of observation group in the first 6 months and the first year was 88.0%,84.0%,control group was 90.0%,88.0%respectively,without significant difference between the two groups(P＞0.05);the average alveolar resorption of observation group and control group in the first 6 months and the first year were(0.63±0.11)mm,(1.25±0.23)mm,control group was(0.42±0.08)mm,(1.01±0.12)mm,respectively;the observation group was slightly higher than that of control group,but the difference was not significant(P＞0.05). Conclusion Application of implantation repair therapy has better effect in clinical treatment of chronic periodontitis patients with dentition defect,which can restore the physiological function of patients,improve the quality of life and is worth popularizing in clinical use.
2017 Vol. 24 (5): 109-111 [Abstract] ( 117 ) HTML (40 KB)  PDF  (0 KB)  ( 41 )
112 Comparison of the effect of intravenous anesthesia and inhalation anesthesia on the postoperative cognitive functions of elderly patients
YANG Qi-lin
Objective To compare the effect of intravenous anesthesia and inhalation anesthesia on the postoperative cognitive functions of elderly patients.Methods 120 cases of elderly patients received surgery from June 2015 to July 2016 in our hospital were selected and divided into the intravenous anesthesia group(60 cases)and inhalation anesthesia group (60 cases)according to the method of keeping anesthesia during operation.Patients in intravenous anesthesia group were given Propofol+Remifentanil intravenous infusion,while patients in inhalation anesthesia group were given inhalation of Sevoflurane+50%NO.The operative time,amount of bleeding,transfusion volume,the incidence of hypotension,nausea,vomiting during operation,the time of eyes open,tube drawing and response were compared between the two groups;the MMSE score before anesthesia and 1,3,12,24 h after response and the incidence of POCD of two groups were compared.Results There was no statistically significant difference in operation time,amount of bleeding,transfusion volume and the incidence of hypotension,nausea and vomiting during operation between the two groups(P＞0.05).The time of eyes open,tube drawing and response in the intravenous anesthesia group was shorter than that of the inhalation anesthesia group,and the difference was statistically significant(P＜0.01).There was no statistically significant difference in MMSE score before anesthesia between the two groups(P＞0.05).After answering,the MMSE scores of 1,3 and 12 h in intravenous anesthesia group were higher than those of inhalation anesthesia group,and the differences were statistically significant(P＜0.01).But there was no statistically significant difference between the MMSE sores of 24 h in two groups (P＞0.05);the incidence of POCD was 18.3%in the intravenous anesthesia group,that in the inhalation anesthesia group was 23.3%,and there was no statistically significant difference between the two groups(P＞0.05).Conclusion Intravenous anesthesia and inhalation anesthesia may have some influence on postoperative cognitive function in elderly patients,but the former has a relatively shorter time and faster postoperative recovery.
2017 Vol. 24 (5): 112-114转127 [Abstract] ( 147 ) HTML (44 KB)  PDF  (0 KB)  ( 38 )
115 Application of Ketorolac Tromethamine combined with Remifentanil in lumbar endoscopic surgery under local anesthesia
LI Li;OUYANG Ai-ping;HUANG Qi-wen;HUANG Gui-ming
Objective To observe the analgesic effect of Ketorolac Tromethamine combined with Remifentanil in lumbar endoscopic surgery under local anesthesia,and its frugal role for Remifentanil.Methods Fifty patients received lumbar endoscopic surgery from January 2014 to December 2015 were selected and they were randomly divided into group R (n=25)(Remifentanil assisted by local anesthesia)and group TR(n=25)(Ketorolac Tromethamine combined with Remifentanil assisted by local anesthesia).Group R was intravenous injected normal saline 5 ml while group TR was intravenous injected Ketorolac Tromethamine 30 mg,they all were given drugs before 20 minutes surgery.Before local anesthesia,Remifentanil were given in the two groups initial dosage of 0.25 μg/kg and then continuous infused in dosage of 0.1μg/(kg·min), and adjusting the infusion speed.1%lidocaine local anesthesis was given by operator before surgery.During surgery,BP and HR were recorded and the usage amount of Remifentanil was calculated,and the occurrence of low blood pressure, bradyarrhythmia,respiratory depression and nausea vomiting were recorded.Results MAP and HR of group TR were lower compared to group R in the period of T2-T5(P＜0．05),but the two group has no difference in the period of T6(P＞0．05).In group TR,the consumption of Remifentanil was less,and the occurrence rate of respiratory depression and nausea vomiting was also reduced (P＜0．05).Low blood pressure and bradyarrhythmia does not happened in the two groups (P＞0．05).Conclusion Ketorolac tromethamine combined with Remifentanil may provide better analgesia effect,and can obviously reduce the consumption of Remifentanil and decrease the incidence of adverse reaction during surgery in lumbar endoscopic surgery under local anesthesia.
2017 Vol. 24 (5): 115-117 [Abstract] ( 159 ) HTML (39 KB)  PDF  (0 KB)  ( 34 )
118 Analysis of the anesthetic effect of nerve block combined with different intravenous general anesthetics on infants′inguinal hernia sac high ligation
ZHOU Fang;DU Yun-fei;LIN Min;GUI Xue-mei;WEN Bei-bei
Objective To study the anesthetic effect of nerve block combined with different intravenous general anesthetics on infants′inguinal hernia sac high ligation.Methods 150 children from 6 months to 3 years of age given high ligation of inguinal hernia sac in our hospital from October 2014 to August 2016 were selected and they were randomly divided into 3 groups according to the random number table method,groupⅠ:intravenous injection of Fentanyl 2 μg/kg and Propofol 2.5 mg/kg;groupⅡ:intravenous injection of Ketamine 2 mg/kg and Propofol 2.5 mg/kg; groupⅢ:intravenous injection of Ketamine 2 mg/kg.When children′s awareness disappeared,0.3 ml/kg mixture of 0.5% Lidocaine and 0.25%Ropivacaine was used to perform ipsilateral iliohypogastric and ilioinguinal nerve block.If the body reaction occurred during the operation,then groupⅠ and groupⅡwere given intravenous injection of Propofol 0.5-1.0 mg/kg,and groupⅢwas given Ketamine 1 mg/kg until the body reaction disappeared;the change of heart rate (HR),respiratory rate (RR)and percutaneous oxygen saturation (SpO2)at different time points,and awakening time and complications were observed and compared.Results The change of HR in groupⅠ and groupⅢ at different time points were different with those before operation (T0),and the difference was statistically significant(P＜0.05).HR was compared at the same time points in each group:the differences at T1,T2,T3were statistically significant(P＜0.05);the change of RR and SpO2among the three groups had no statistical difference (P＞0.05);the awakening time in groupⅢwas the longest.The awakening time was the shortest in groupⅠ,and the sedation score was the most satisfactory; complications and adverse reactions were the most in groupⅢ and the least in groupⅠ.Conclusion Intravenous injection combined with nerve block anesthesia by Fentanyl 2 μg/kg and Propofol 2.5 mg/kg is the best.
2017 Vol. 24 (5): 118-121 [Abstract] ( 163 ) HTML (52 KB)  PDF  (0 KB)  ( 46 )
122 Influence of Ondansetron and Droperidol on postoperative nausea and vomiting followed with laparoscopic cholecystectomy
LIU Ying;WANG Long-ping;FANG Ming;PENG Guo-qing
Objective To investigate the influence of Ondansetron and Droperidol on postoperative nausea and vomiting followed with laparoscopic cholecystectomy.Methods From Januarry to June 2016,80 patients undergoing laparoscopic cholecystectomy treatment admitted into our hospital were selected randomly,and these odd patients were divided into Ondansetron group(n=40)and those even Droperidol group(n=40)two groups according to the random number table,VAS score,Ramsay score,total amount of drug,PCA volume,incidence rate of nausea and vomiting and severity,and adverse reaction between two groups were statistically analyzed.Results The total amount of drug,PCA in 2ndday of the two groups were significantly lower than in 1stday (P＜0.05).The Ramsay score in 1stday,2ndday of the Ondansetron group were significantly less(P＜0.05).The incidence rate of nausea and vomiting in 1stday (2.5%)was significantly lower than the Droperidol group(22.5%)(P＜0.05),in which the proportion of level 0 was significantly higher(P＜0.05),the proportions of level 1,level 2 and level 3 were significantly lower(P＜0.05).the incidence rate of adverse reactions(25.0%)was significantly lower than the Droperidol group of 40.0% (P＜0.05).Conclusion Ondansetron has more positive effect for nausea and vomiting after laparoscopic cholecystectomy compared with droperidol.
2017 Vol. 24 (5): 122-124 [Abstract] ( 132 ) HTML (40 KB)  PDF  (0 KB)  ( 32 )
125 Application effect of premedication of Dexmedetomidine in hypertensive patients undergoing radical gastrectomy
ZHAN Yan-ping;CHEN Shi-biao
Objective To explore the application effect of premedication of Dexmedetomidine in hypertensive patients undergoing radical gastrectomy.Methods From May 2015 to May 2016,108 patients with hypertension treated by laparoscopic radical gastrectomy in our hospital were selected as study objects and they were randomly divided into control group and observation group,with 54 cases in each group.Patients in the observation group were given Dexmedetomidine (0.6 μg/kg)before the induction of anesthesia,and in the control group,the same volume of saline was provided.Heart rate(HR),mean arterial pressure(MAP)and oxyhemoglobin saturation(SpO2)were observed before anesthesia induction (T0),extubation(T1),5 minutes after extubation(T2),and 10 minitues after extubation(T3).The incidence rate of adverse reactions between two groups was compared.Results There was no significant difference between the two groups in T0period and the difference of SpO2from T1-T3was not significant(P＞0.05).At T1-T3,indexes of HR and MAP in the observation group were both lower than those in the control group (P＜0.05).The incidence rate of adverse reactions in the control group and observation group was 38.89%and 14.81%with a statistical difference(P＜0.05).Conclusion Premedication of Dexmedetomidine can reduce the restlessness and adverse reaction of general anesthesia during recovery period.
2017 Vol. 24 (5): 125-127 [Abstract] ( 145 ) HTML (38 KB)  PDF  (0 KB)  ( 43 )
128 Observation of the effectiveness of GM-1 in treatment of cerebrovascular disease patients with cognitive impairment
ZHANG Zhen-ping;ZHONG Guang-shi;DENG Yu-peng
Objective To study the clinical curative effect and application value of GM-1 (Monosialotetrahexosyl ganglioside)in treatment of patients with cerebral vascular cognitive impairment.Methods Altogether 86 cases of cerebral vascular cognitive impairment who were treated in our hospital from January 2013 to January 2016 were randomly divided into two groups according to the random number method,43 cases were treated with conventional therapy and classified as control group,while,another 43 patients were treated with GM-1 on the basis of control group and classified as obser-vation group.The clinical efficacy and cognitive function improvement in two groups were compared.Results The total effective rate of observation group was 86.04%,significantly higher than that of control group of 58.13%(P＜0.05).The total MMSE score of observation group was(29.04±4.75)points,significantly higher than that of control group of(18.68±4.51)points(P＜0.05).Conclusion GM-1 demonstrates has better curative effect in the treatment of cerebral vascular cognitive impairment,and it can improve patients′cognitive function and brain function.
2017 Vol. 24 (5): 128-130 [Abstract] ( 125 ) HTML (37 KB)  PDF  (0 KB)  ( 38 )
131 Effect of Clostridum Butyricum Capsule in treating newborns antibiotic associated diarrhea
LONG Zheng;DU Sheng;LI Jie-fang
Objective To explore the clinical effect of Clostridum Butyricum Capsule in treating newborns antibiotic associated diarrhea.Methods 100 newborns with antibiotic associated diarrhea in our hospital from January 2015 to June 2016 were selected as study objects and were divided into observation group and control group by using number table, 50 cases in each group.The control group was used Montmorillonite Powder,the observation group was used Clostridum Butyricum Capsule on the basis of control group.Clinical effect,main symptom improvement time and treatment related adverse reactions in two groups were compared.Results In the observation group,33 cases were markedly effective,effective in 15 cases,ineffective in 2 cases,the total effective rate was 96.0%,which were respectively 21,16,13 and 74.0%in control group,the observation group was obvious better than control group and the difference was significant(χ2=6.414, P＜0.05);stool recovery time,vomiting disappearance time and fever disappearance time in observation group were respectively（3.2±1.0）,（2.1±0.4）and（2.2±0.6）d,which were respectively（5.2±1.5）,（4.6±1.1）and（4.5±1.0）d in control group,and the difference was significant(P＜0.05).No drug related adverse reactions occurred in two groups during treatment.Conclusion Clostridum Butyricum Capsule has exactly effect in treating newborns antibiotic associated diarrhea, which can quickly improve the main clinical symptoms of children,with good safety and is worthy to promotion and application in clinical.
2017 Vol. 24 (5): 131-133 [Abstract] ( 136 ) HTML (36 KB)  PDF  (0 KB)  ( 43 )
134 The feasibility analysis of the somatostatin and snake venom blood clotting enzyme combined with Omeprazole in the treatment of acute upper gastrointestinal bleeding
ZENG Zhi-ming
Objective To explore the effect of Omeprazole combined with somatostatin and snake venom blood clotting enzyme in the treatment of acute upper gastrointestinal bleeding.Methods From March 2013 to March 2016,82 acute upper gastrointestinal bleeding patients were randomly divided into experimental group and control group,41 cases in each groups.The experimental group was adopted Omeprazole combined with somatostatin and snake venom blood clotting enzyme,the control group only was adopted Omeprazole.The hemostatic effect,hemostatic time,the incidence of adverse reactionsand patients′satisfaction of two groups were compared Results The hemostatic effect and the patients′satisfaction were significantly higher than those of control group (P＜0.05),the hemostatic time was significantly shorter than the control group(P＜0.05),the incidence of adverse reactions was lower than that of control group,that of difference was significant(P＜0.05).Conclusion The experimental group has exact curative effect,shorter hemostatic time and less adverse reactions.The patients are almost satisfied with it,which is worth to promoting.
2017 Vol. 24 (5): 134-136 [Abstract] ( 166 ) HTML (42 KB)  PDF  (0 KB)  ( 37 )
137 Effect of Bushen Kangshuai Tablets combined with traditional western medicine in the treatment of type 2 diabetic nephropathy of kidney deficiency and phlegm stagnation in elderly patients
HUANG Guo-wei
Objective To explore the clinical effect of Bushen Kangshuai Tablets combined with conventional western medicine in the treatment of type 2 diabetic nephropathy of kidney deficiency and phlegm stagnation in elderly patients.Methods 194 patients with type 2 diabetic nephropathy of kidney deficiency and phlegm stagnation who were treated in our hospital from April 2013 to April 2016 were selected and divided into observation group (n=97)and control group (n=97)according to the odd number and even number of the admission number.Patients in the control group were only given conventional western medicine,while patients in the observation group were treated with Bushen Kangshuai Tablets on the basis of the control group.Biochemical indicators and improvement of symptoms of traditional Chinese medicine before and after treatment were compared between two groups.Results After 16 weeks of treatment, the biochemical indicators and TCM syndrome scores of two groups was significantly lower than that before treatment (P＜0.05);lymphocyte group CD4+/CD8+,urinary ACR,urinary Alb,FBG,2 h PBG,HbA1c in the observation group were all better than those in the control group,and the difference was statistically significant(P＜0.05);improvement of scores of shortness of breath and laziness to speak,limb numbness,frequent urination,low back pain,abdominal fullness and distention in the observation group was better than that in the control group respectively,and there was statistical difference (P＜0.05).Conclusion Bushen Kangshuai Tablets combined with conventional western medicine in the treatment of type 2 diabetic nephropathy of kidney deficiency and phlegm stagnation in elderly patients is safe and effective.It can effectively maintain the blood sugar level,regulate the immunity of the body and improve the physical syndromes of TCM,which can be promoted and applied in clinical treatment.
2017 Vol. 24 (5): 137-139 [Abstract] ( 133 ) HTML (37 KB)  PDF  (0 KB)  ( 40 )
140 Effects of Yangxin Tongmai Mixture on cardiac function and neuroendocrine factor of patients with chronic heart failure
HE Xin-bing;WEN Zhi-hao;LIU Xue-ling;PAN Chao-xin;WANG Qing-gao;HUANG Ming-jian
Objective To observe the effect of Yangxin Tongmai Mixture on the cardiac function and neuroendocrine factors in patients with chronic heart failure.Methods 69 patients with chronic heart failure patients in our hospital from June 2013 to December 2015 were divided into control group(n=33)and treatment group(n=36)according to random number table method,patients in the control group were treated routinely with western medicine,while patients in the treatment group were added with Yangxin Tongmai Mixture.The change of AngiotensinⅡ(AngⅡ),N-terminal brain natriuretic peptide precursor(NT-ProBNP)and left ventricular ejection fraction(LVEF),A ldosterone(ALD),level before and after treatment were compared.Results There was no significant difference in the levels of NT-ProBNP,LVEF,AngⅡand ALD before treatment between two groups(P＞0.05).After 8 weeks of treatment,LVEF level in two groups was higher than that before treatment,while NT-ProBNP level was significantly decreased (P＜0.01),and which in the treatment group was significantly improved,the difference was statistically significant(P＜0.05).After 8 weeks of treatment,the levels of AngⅡ and ALD in two groups was lower than that before treatment,the difference was statistically significant (P＜0.05),which in the treatment group was significantly lower than that in the control group(P＜0.05).Conclusion Yangxin Tongmai Mixture can significantly improve the cardiac function and quality of life of patients with chronic heart failure, suppress over activation of neuroendocrine.
2017 Vol. 24 (5): 140-142 [Abstract] ( 124 ) HTML (41 KB)  PDF  (0 KB)  ( 33 )
143 Clinical observation of Houposanwu Decoction for enema in the treatment of intractable abdominal distension due to thoracolumbar spine fracture in 120 cases
WANG Jun;TAO Xiao-bing;LIU Xiao-hui;CHEN Yan-ping;CHU Ding-kun;LIU Hong-zheng
Objective To explore the clinical effect of Houposanwu Decoction for enema in the treatment of intractable abdominal distension due to thoracolumbar spine fracture.Methods After being approved by Medical Ethics Committee of our hospital,a prospective,double-blind,randomized,controlled study was conducted in 120 patients with refractory abdominal distension after thoracolumbar fracture in our hospital from March 2015 to March 2016.They were selected as research objects and evenly divided into two groups in random.In control group(n=60),patients were treated by regular intramuscular injection of Neostigmine,while in treatment group(n=60),Houposanwu Decoction for enema was adopted.The abdominal distension relief after medication,exhaust time,and defecation time in the two groups were observed. Results The marked improvement rate and total effective rate in the control group was 55.00%and 83.33%,and in the treatment group,they were 73.33%and 95.00%respectively,with statistical difference(P＜0.05).After therapy,the exhaust time was(0.87±0.18)h in the control group,while(0.39±0.14)h in the treatment group,with statisticant difference(P＜0.05).The defecation time in the control group and treatment group was(2.23±0.32)h and(1.21±0.33)h,with statisticant difference(P＜0.05).Conclusion Houposanwu Decoction for enema can greatly alleviate the symptoms of abdominal distension in patients with intractable abdominal distension due to thoracolumbar spine fracture and shorten the time of abdominal distension at advantages of being simple and easy to perform,and reliable on effect,which is especially suitable for promotion in grass-roots hospitals.
2017 Vol. 24 (5): 143-145转158 [Abstract] ( 142 ) HTML (47 KB)  PDF  (0 KB)  ( 32 )
146 Study of the relevance between nurse occupational burnout and mental health status
LUO Hui-juan;XIAO Qi-xiu;WANG Li-rong
Objective To explore the relevance between nurse occupational burnout and mental health status,so as to provide evidences for hospital management.Methods Anonymous questionnaire was carried out for 152 nurses in 3 hospitals in Huizhou Area in January 2016,including MBI and SCL-90.The relevance between SCL-90 and MBI was analyzed.Results The proportions of emotional exhaustion,depersonalisation and diminished personal accomplishment with different degrees in the clinical nurses was 30.3%,52.6%and 57.9%respectively.The differences of the three dimensions of occupational burnout levels,namely emotional exhaustion,depersonalisation and diminished personal accomplishment,in the nurses in different department were statistically significant(P＜0.01).The scores of 10 factors in SCL-90 and the total scores were compared with China normal scores,and the differences were statistically significant (P＜0.05). Conclusion Nurses in the hospital in Huizhou Area show different degrees of occupational burnout,which are closely relevant with nurses′mental health status.
2017 Vol. 24 (5): 146-148 [Abstract] ( 148 ) HTML (41 KB)  PDF  (0 KB)  ( 35 )
149 Application effect of DUR and DUE in the evaluation of drug use in patients with community acquired pneumonia
GU Man-hua;GUO Hua-chun;HUANG Jun-qing
Objective To evaluate the application effect of DUR and DUE in the evaluation of drug use in patients with community acquired pneumonia.Methods 107 patients with community acquired pneumonia treated in Department of Respiration of People′s Hospital of Tianhe District in Guangzhou City from January 2015 to August 2016 were comprehensively analyzed by DUR and DUE.Results A total of 21 antimicrobial agents were used in the treatment of patients,and drugs DUI of 5 cases were more than 1,which were Cefuroxime Sodium,Ceftazidime,Amoxicillin Dispersible Tablets,Itraconazole Capsules and Cefepime.The evaluation results showed that prescription were too large and drug used were irrational.7 patients had adverse drug reactions in the process of hospitalization,96.3%of the patients showed obvious improvement after treatment.Another 4 patients abandoned hospitalization.Conclusion The combined used of DUR and DUE can evaluate the use of antimicrobial agents in primary hospitals more comprehensively,discover unreasonable drug use,promote the management of drug resources,and promote the establishment and perfection of hospital drug system.
2017 Vol. 24 (5): 149-151 [Abstract] ( 147 ) HTML (37 KB)  PDF  (0 KB)  ( 33 )
152 Analysis on the use of human albumin in 203 cases in a hospital from January to June 2016
LAI Yan-jin
Objective To investigate the use of human albumin in 203 cases in a hospital so as to provide reference for its clinically rational use.Methods A retrospective review was conducted to collect and analyze the data of use of human albumin in 203 cases from January to June 2016 according to drug instructions and related guidelines.Results Altogether 19 960 g albumin was used by 203 cases of patients,and the dose per capita was 98.32 g.The duration of medication ranged from 1 to 27 days.The drug was prescribed mainly for patients with hypoalbuminemia(41.38%).In some cases,the drug was used without clinical indications or disregarding the contraindications.Conclusion In view of the unreasonable use of human albumin in the hospital,the indications should be strictly mastered,the instructions and related guidelines should be followed and the standardized use of blood products should be strengthened.
2017 Vol. 24 (5): 152-154 [Abstract] ( 146 ) HTML (38 KB)  PDF  (0 KB)  ( 32 )
155 Investigation and analysis serum vitamin D level of 4525 children in Longgang District of Shenzhen City in 2016
XIA Hong-bo;XING Meng-meng;ZHANG Bao
Objective To analyze the serum vitamin D level of children in Longgang District of Shenzhen City.Methods 4525 healthy children aged 0 to 14 years old from October 2015 to September 2016 of our hospital were collected. Serum samples were collected.ELISA was used to detected the level of serum 25-(OH)D and the clinical data were analyzed retrospectively.Results The average 25-(OH)D level of aged 0 to 14 years old children was(31.44±9.53)ng/ml. Less than 2195 cases(48.51%)with vitamin D deficiency;serum 25-(OH)D levels in 2713 boy cases were lack,severe lack in 246 cases(3.85%)and deficiency in 1039 cases(22.96%);Serum 25-(OH)D levels in 1812 girl cases were lack, severe lack in 174 cases(3.85%)and deficiency in 736 cases(39.23%).The difference of vitamin D level and deficiency vitamin D between boys and girls had no statistical significance(P＞0.05);serum 25-(OH)D level in infant group was (35.97±12.34)ng/ml,which was obviously higher than was[(22.66±19.00)ng/ml]in 12-13 years old children,and the difference was significant(P＜0.05),summer and autumn were significantly higher than those in spring and winter,there were signifi cant differences in 25-(OH)D and vitamin D deficiency among different age groups and seasons(P＜0.05).Conclusion The vitamin D deficiency is higher in children in Longgang area,which relates to age and season and attention should be paid to prevention.
2017 Vol. 24 (5): 155-158 [Abstract] ( 165 ) HTML (45 KB)  PDF  (0 KB)  ( 39 )
159 Round integration into the concept of running a hospital in accordance with the law to promote the harmonious and scientific development of hospital
ZHU Ji-wen;WANG Rong-gui;XU Yang
In order to meet the needs of society,the hospital must follow the road of administering a hospital according to law.As a maternity and child care institution,our hospital integrated the concept of hospital management according to a law into every management level,developed the legal environment of administration,decision,and operation in the hospital,and improve the level of hospital scientization,normalization,and institutionalization so as to boost up the rapid development of the hospital.
2017 Vol. 24 (5): 159-162 [Abstract] ( 116 ) HTML (47 KB)  PDF  (0 KB)  ( 24 )
163 Effect of three-dimensional nursing management model on the quality of pre-hospital emergency for critically-ill patients
HUANG Qiong-fang;WU Zao-lian;KONG Jian-yi;HUANG Shu-xian
Objective To study the effect of three-dimensional(3D)nursing management model on the quality of prehospital emergency care for critically-ill patients.Methods Altogether 80 critically-ill patients who were treated in our hospital from January 2014 to May 2015 were selected and randomly divided into two groups,including routine group and 3D group.The routine nursing management mode was adopted as the pre-hospital emergency care in routine group while,the 3D nursing management model was taken for patients in 3D group.The rescue success rate,the incidence of medical disputes,and patients,their families and emergency doctors′evaluation of pre-hospital nursing service satisfaction as well as the difference between pre-hospital emergency nurses′emergency consciousness score,rapid response ability score and healthcare staff coordination score were compared.Results Patients in 3D Group had higher rescue success rate and lower incidence of medical disputes than routine group (P＜0.05);the patients,their families and emergency doctors′evaluation of pre-hospital nursing service satisfaction in 3D group was higher than that of Routine group (P＜0.01);the pre-hospital emergency nurses′emergency consciousness score,rapid response ability score and healthcare staff coordination score of patients in 3D group were higher than those of routine group(P＜0.01).Conclusion The threedimensional nursing management model has great influence on the quality of pre-hospital emergency care for critically-ill patients and can effectively improve the comprehensive quality of pre-hospital emergency nursing staff,the rescue success rate as well as the patients,their families and emergency doctors′satisfaction of pre-hospital nursing service, which plays a remarkable role in avoidance of the occurrence of medical disputes and is worthy of promotion.
2017 Vol. 24 (5): 163-165 [Abstract] ( 126 ) HTML (38 KB)  PDF  (0 KB)  ( 33 )
166 Application of the standardization management model of doctor-nurse integration in electronic medical order process
CHEN Jie;DENG Shu-hong;XU Fang
Objective To study the application value of standardization management model of doctor-nurse integration in electronic medical order process.Methods 200 patients from July 2015 to June 2016 in our department were selected,according to a random number table method,200 cases were divided into the observation group and the control group,100 cases in each group.The control group was given the traditional process of electronic medical order,the observation group was given the standardization management model of doctor-nurse integration in the process of electronical medical order.The speed of managing medical order,the error rate of medical order and the error rate of charge of the two groups were compared.Results The error rate of medical order in the observation group was 3%,the speed of managing medical order in the observation group was(20.8±13.6)min/100 items.The error rate of medical order in the control group was 8%,the speed of managing medical order in the control group was(23.7±12.8)min/100 items,there was significant difference between the two groups (P＜0.01).The error rate of the observation group was 17%,which was lower than that of the control group (21%),with significant difference (P＜0.05).Conclusion The standardization management model of doctor-nurse integration in the process of electronical medical order can regulate the medical order writing and entering,program the manage process of medical order,improve the accuracy and speed of medical order management,strengthen medical collaboration and perfect the charging mechanism.
2017 Vol. 24 (5): 166-168 [Abstract] ( 120 ) HTML (39 KB)  PDF  (0 KB)  ( 33 )
169 Application effect analysis of surgical-instrument-and-hand integrated management in endoscopic surgery
HE Yong-hong;CHEN Yue-fang;TAN Sheng-yan;LIU Yan-ping
Objective To explore the influence of surgical-instrument-and-hands integrated management in endoscopic surgery on clinical effect.Methods 400 patients who have been performed an endoscopic surgery in the Sixth Hospital Affiliated to Sun Yat-sen University from January 2015 to June 2016 were selected as the research object,and they were divided into the control group and the observation group according to the random number table method,200 cases in each group.The control group was performed an operation in a routing way,while the observation group was given an surgical-instrument-and-hand integrated management.The operation time and the degree of total satisfaction in the two groups were compared.Results The operation time in the observation group was （60.52±9.56）min,which was shorter than that in the control group of（78.32±9.36）min,with significant difference（P＜0.05）.The degree of total satisfaction of the observation groupwas 97.0%,which was higher than that of the control group （87.0%）,with significant difference（P＜0.05）.Conclusion In the process of the endoscopic surgery,surgical-instrument-and-hand integrated management can effectively shorten the operation time and improve patients′satisfaction,achieve ideal clinical effect.Therefore,it is worth of further promotion.
2017 Vol. 24 (5): 169-171 [Abstract] ( 100 ) HTML (34 KB)  PDF  (0 KB)  ( 32 )
172 Effect of HEDIS system nursing model on quality of life in asthmatic children
XIE Qiong;ZHANG Jian-rong;CHEN Mei-ping;ZHANG Shu-qing
Objective To explore the effect of health care effective data and information system (HEDIS)nursing model on the quality of life in children with asthma.Methods One hundred asthmatic children visited our hospital due to asthma attack from June 2013 to June 2016 were selected.According to the odd or even number of outpatient service or hospitalization,they were randomly divided into research group(n=50)and control group(n=50).In the control group,traditional nursing mode was applied,while in the research group,HEDIS for asthmatic children was adopted.The nursing effect between two groups was compared.Results The asthma control,treatment compliance,self-management of health behaviors in the research group were all better than those in the control group with statistical difference(P＜0.05).Conclusion HEDIS system nursing mode extends health education to family,ensures long-term,standardized,sustained,individualized treatment for pediatric patients,and can effectively control the onset of asthma,reduce the disease recurrence, and improve QOL in children patients.
2017 Vol. 24 (5): 172-174 [Abstract] ( 142 ) HTML (35 KB)  PDF  (0 KB)  ( 39 )
175 Analysis of influence of nursing management of negative emotions and quality of life in elderly patients with chronic bronchitis
ZHENG Xue-mei
Objective To explore the influence of nursing management of negative emotions and quality of life in elderly patients with chronic bronchitis.Methods 84 elderly patients with chronic bronchitis treated in our hospital from January to December 2015 were selected and they were divided into control group(n=42)and study group(n=42).Patients in the control group were given basic nursing,while the study group was given nursing management on the basis of basic nursing.SAS and SDS score,life quality score and satisfaction degree of nursing in patients between two groups were compared.Results SAS and SDS score in the study group[(41.6±2.5)points and(42.2±2.1)points]were lower than those of the control group [(73.6±2.2)points and (74.3±2.2)points],and quality of life was significantly better than that of control group,and the satisfactory degree was obviously better than that of the control group(P＜0.05).Conclusion Basic nursing and nursing management have been done for elderly patients with chronic bronchitis to improve their quality of life.
2017 Vol. 24 (5): 175-178 [Abstract] ( 161 ) HTML (48 KB)  PDF  (0 KB)  ( 24 )
179 Application effect of comprehensive nursing intervention in patients with lung cancer after total lung resection and bronchial fistula
CAO Qing-li
Objective To explore the application effect of comprehensive nursing intervention in patients with lung cancer after total lung resection and bronchial fistula.Methods 24 cases with lung cancer complicated with bronchial fistula after total lung resection treated in our hospital from January 2009 to January 2015 were randomly divided into observation group and control group,12 cases in each group.Control group was given conventional nursing measures,while observation group was given targeted systematic and comprehensive nursing measures.Mortality,hospitalization time and postoperative complication rate in patients between two groups were compared.Results In the observation group,12 patients were cured,the cure rate was 100.00%;the control group 8 cases were cured,2 patients died,the cure rate was 66.66%;length of stay of the observation group of patients was(31.6±6.2)d,the incidence of postoperative complications was 8.33%,patients in the control group the hospitalization time was(40.1±7.5)d,postoperative complication rate was 50.01%,and the cure rate of the observation group was significantly higher than that of control group (P＜0.05),the hospitalization time was significantly shorter than that of control group(P＜0.05),the incidence of complications was significantly less than that of the control group (P＜0.05).Conclusion Comprehensive nursing intervention for patients with bronchial pleural fistula can shorten the hospitalization time and reduce the mortality.
2017 Vol. 24 (5): 179-181 [Abstract] ( 165 ) HTML (36 KB)  PDF  (0 KB)  ( 36 )
181 Effect of systematic nursing on improvement of the social regression rate for maintenance hemodialysis patients
HE Qing-xuan;XIONG Yu-wan;HE Xing-lai;LYU Wei
Objective To explore the effect of systematic nursing on improvement of the social regression rate for maintenance hemodialysis patients.Methods Altogether 300 cases of maintenance hemodialysis patients who were treated in Maintenance Hemodialysis Center of four GradeⅢA Hospitals in Guangdong Province from January 2014 to January 2016 were retrospectively analyzed and randomly divided into intervention group and control group,150 cases in each group.The intervention group were received systematic nursing intervention based on routine nursing;while,the control group only were received routine nursing intervention.After 6 months of intervention,the social regression rate,SSRS(Social Support Rating Score),SAD(Social Avoidance and Distress Scale),medical compliance behavior and the incidence of complications of two groups were compared.Results The post-interventional social regression rate and SSRS score of the two groups were higher than pre-interventional ones,with significant difference(P＜0.05),among which a more significant improvement was seen in intervention group(P＜0.05).The regular hemodialysis rate,reasonable dietand work and rest rate,strict water intakerate of intervention group were higher than those of control group (P＜0.05).The SAD scores of the two groups were lower than pre-interventional ones,with significant difference(P＜0.05),among which a more significant reduction was seen in intervention group(P＜0.05).The incidence of complications in intervention group was significantly lower than that in control group(P＜0.05).Conclusion Systemic nursing intervention can help to enhance patients′self-confidence,improve communication avoidance and distress,strengthen social support and medical compliance, reduce the complications and improve the quality of life,which assistspatients to return to society earlier and it is worthy of promotion.
2017 Vol. 24 (5): 181-184转187 [Abstract] ( 173 ) HTML (48 KB)  PDF  (0 KB)  ( 36 )
185 Application effect of care services for post-abortion women in nursing clinics by specialized nurses
HU Wen-juan;ZHENG Xing-shan;ZHENG Li-qian
Objective To explore the application effect of care services for post-abortion women in nursing clinics by specialized nurses.Methods From May 2013 to May 2014,200 patients with abortion were selected in our hospital and evenly divided into observation group and control group in random.The observation group was provided care service from nursing clinics by specialized nurses,while in the control group was not adopted care service.The questionnaire investigations were carried out in different ways and the nursing outcomes were compared.Results The contraceptive efficiency after abortion in the observation group was significantly different than that in the control group (P＜0.05).The contraceptive method in the observation group was greatly different than that in the control group with statistical significance (P＜0.05).Frequency of contraception during non-safe period between the observation group was compared with control group,with significant difference (P＜0.05).The score of knowledge about contraception in the observation group was higher than that in the control group with great difference in statistical significance (P＜0.05).Conclusion Care service in nursing clinics by specialized nurses can greatly reduce re-abortion rate and improve patients′understanding of reproductive health knowledge,which is worthy of promotion and application.
2017 Vol. 24 (5): 185-187 [Abstract] ( 126 ) HTML (35 KB)  PDF  (0 KB)  ( 33 )
188 Effect of continuing nursing on living ability and psychology and social adaptation of patients with hypertensive cerebral hemorrhage after discharge
LIN Shao-yun;MAO Shu-yun;LI Hui-yi
Objective To investigate the effect of continuing nursing on living ability and psychology and social adaptation of patients with hypertensive cerebral hemorrhage after discharge.Methods The clinical data of 68 patients with hypertensive intracerebral hemorrhage who were admitted to our hospital from January 2014 to June 2016 were analyzed.According to different nursing measures,the patients were divided into control group of 30 cases and the continuing nursing group of 38 cases.The evaluation of neurological deficits,the evaluation of daily living ability,the psychological emotion score and the social support score were observed in two groups.Results The evaluation of neurological deficit in the continuing nursing group was better than that in the control group,the ability of daily life activities was better than that in the control group,the scores of anxiety and depression were higher than those in the control group,social support score was lower than that in the control group (P＜0.05),and the difference was significant.Conclusion The application of continuing nursing care in the patients with hypertensive intracerebral hemorrhage can improve the recovery of neurological function and ability of living,improve the psychological emotions and improve the social support. It is worthy of clinical promotion and application.
2017 Vol. 24 (5): 188-190转193 [Abstract] ( 146 ) HTML (39 KB)  PDF  (0 KB)  ( 42 )
191 Research of nursing quality rehabilitation in patients with glioma
HUANG Zhi-qing;LYU Shu-xi;WANG Hao;HU Ji-liang;LYU Wen
Objective To explore the effect of nursing quality on the recovery of glioma patients.Methods 120 patients with glioma were treated in our hospital from January 2013 to January 2016,they were divided into nursing group and control group,60 cases in each group.The control group patients were treated with routine nursing contents,the nursing group patients were used high-quality care mode.The scores of nursing satisfaction,SDS score and SAS score of different nursing contents were compared.Results The satisfaction degree of the nursing group was 98.3%,and the satisfaction degree of the control group was 70.0%,the difference was significant(P＜0.01).SDS and SAS scores showed that the psychological status of patients after nursing care have different degrees of improvement.The SDS and SAS scores of nursing group were compared with control group,the difference was significant(P＜0.01).The ECOG score was (1.5±0.4) scores in the nursing group and the control group was(2.3±0.8)scores,with significant difference(t=6.928,P＜0.01).Conclusion The quality of care model can provide patients with higher quality of care,and can significantly improve patient care satisfaction,it improves their compliance,effectively improve the psychological and physical condition of patients and other rehabilitation effects,it is worthy of clinical reference.
2017 Vol. 24 (5): 191-193 [Abstract] ( 140 ) HTML (39 KB)  PDF  (0 KB)  ( 38 )
194 Nursing effect of clinical part-time clinical specialist nurses during perioperative period of patients with intestinal stoma
ZHANG Feng-ying;XIE Hong-ying;WU Lian-xiang
Objective To investigate the nursing effect of clinical part-time clinical specialist nurses during perioperative period of patients with intestinal stoma.Methods 68 patients with intestinal stoma treated by our hospital from May 2015 to May 2016 were randomly divided into observation group and control group,and there were 34 cases in each group.Patients in observation group were fully taken care of in the perioperative period by part-time clinical specialist nurses,while patients in control group received routine nursing care by responsible shift nurses.Nursing effect between two groups was compared.Results The incidence rate of early complications of patients in the observation group was significantly lower than that in the control group(P＜0.05),hospitalization time was shorter than that of the control group (P＜0.05),the family for the first time for the average cost of a number of ostomy bags was fewer than that of the control group (P＜0.05),satisfaction degree leaving hospital was significantly higher than that of the control group (P＜0.01). Conclusion Through professional and continuous nursing and education,clinical nurse specialist part-time colostomy can reduce the occurrence of early complications for intestinal stoma,reduce the family for the first time the average cost for bags,shorten the length of hospitalization and obviously improve satisfaction degree of patients.
2017 Vol. 24 (5): 194-196 [Abstract] ( 157 ) HTML (40 KB)  PDF  (0 KB)  ( 39 )
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