酮咯酸氨丁三醇复合瑞芬太尼在局麻腰椎孔镜术中的应用

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Abstract Objective To observe the analgesic effect of Ketorolac Tromethamine combined with Remifentanil in lumbar endoscopic surgery under local anesthesia,and its frugal role for Remifentanil.Methods Fifty patients received lumbar endoscopic surgery from January 2014 to December 2015 were selected and they were randomly divided into group R (n=25)(Remifentanil assisted by local anesthesia)and group TR(n=25)(Ketorolac Tromethamine combined with Remifentanil assisted by local anesthesia).Group R was intravenous injected normal saline 5 ml while group TR was intravenous injected Ketorolac Tromethamine 30 mg,they all were given drugs before 20 minutes surgery.Before local anesthesia,Remifentanil were given in the two groups initial dosage of 0.25 μg/kg and then continuous infused in dosage of 0.1μg/(kg·min), and adjusting the infusion speed.1%lidocaine local anesthesis was given by operator before surgery.During surgery,BP and HR were recorded and the usage amount of Remifentanil was calculated,and the occurrence of low blood pressure, bradyarrhythmia,respiratory depression and nausea vomiting were recorded.Results MAP and HR of group TR were lower compared to group R in the period of T2-T5(P＜0．05),but the two group has no difference in the period of T6(P＞0．05).In group TR,the consumption of Remifentanil was less,and the occurrence rate of respiratory depression and nausea vomiting was also reduced (P＜0．05).Low blood pressure and bradyarrhythmia does not happened in the two groups (P＞0．05).Conclusion Ketorolac tromethamine combined with Remifentanil may provide better analgesia effect,and can obviously reduce the consumption of Remifentanil and decrease the incidence of adverse reaction during surgery in lumbar endoscopic surgery under local anesthesia.

Key words： Ketorolac Tromethamine Remifentanil Lumbar endoscope

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	LI Li
	OUYANG Ai-ping
	HUANG Qi-wen
	HUANG Gui-ming

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LI Li,OUYANG Ai-ping,HUANG Qi-wen, et al. Application of Ketorolac Tromethamine combined with Remifentanil in lumbar endoscopic surgery under local anesthesia[J]. 中国当代医药, 2017, 24(5): 115-117.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I5/115

[1]	徐建国.成人术后疼痛治疗进展[J].临床麻醉学杂志，2011，27（3）：299-301.
[2]	KrimmerH，Bullingbum RES，Lloyd J，etal.Effects on biliarytractpressureinhumansofintravenousketorolactromethamine compared with morphine and placebo[J].Anesth Analg，1992，75（2）：204-207.
[3]	Gillian ZH，Maurizio M，Roberta C.How to analyze the Visual Analogue Scale：Myths，truths and clinical relevance[J]. Scand J Pain，2016，13：67-75.
[4]	Ahn Y，Jang IT，Kim WK.Transforaminalpercutaneous endoscopic lumbar discectomy for very high-grade migrated disc herniation[J].Clin Neurol Neurosurg，2016，147：11-17.
[5]	赵学军，左玲，傅志俭，等.经皮椎间孔镜下髓核摘除术治疗腰椎间盘突出症[J].中国疼痛医学杂志，2013，1（1）：72-74.
[6]	李振宙，吴闻有，侯树勋，等.侧后路经皮椎间孔镜下髓核摘除、射频热凝纤维环成形术治疗椎间盘源性腰痛[J].中国微创外科杂志杂志，2009，9（4）：165-168.
[7]	张会东，于松杨，王晓东，等.多模式镇痛的临床研究现状[J].医学综述，2011，17（17）：1072-1074.
[8]	李仕海，余丽珍，贾东林，等.酮咯酸氨丁三醇用于腹腔镜胆囊切除术对患者超前镇痛的观察[J].临床和实验医学杂志，2011，10（24）：1918-1921.
[9]	谢国柱，袁志国，卞丽玉，等.酮咯酸氨丁三醇对舒芬太尼用于老年病人术后镇痛的节俭作用[J].中华麻醉学杂志，2012，5（32）：573-575.
[10]	张志杰.新型非甾体止痛药—酮咯酸氨丁三醇（尼松）[J].中南药学，2008，6（3）：372-374.
[11]	郑叶，陈丽，袁风雷，等.酮咯酸氨丁三醇联合舒芬太尼用于直肠癌根治术术后镇痛的研究[J].中国试验诊断学，2015，5（1）：32-35.
[12]	John F，David C，John D.摩根麻醉学[M].北京：北京大学医学出版社，2015：215-216.
[13]	高洁，张中军，丁娴，等.异丙酚联合酮咯酸氨丁三醇应用于无痛人流手术的临床观察[J].山东医药，2011，51（7）：110.
[14]	Ehrlich GE.Back pain[J].J Rheumatol Suppl，2003，67（2）：26-37.
[15]	高雁，邢玉英，李力兵，等.人工流产术患者瑞芬太尼靶控输注复合异丙酚的效应[J].中华麻醉学杂志，2005，25（6）：472-473.