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2022 Vol. 29, No. 11
Published: 2022-04-18
 
 
4 Study on quality standard of Hedyotis hedyotidea Chinese Herbal Pieces
JI Linfang1 YANG Dequan1▲ SHE Yonghong1 DING Ye2
Objective Develop quality standards for Hedyotis hedyotidea Chinese Herbal Pieces.Methods Hedyotis hedyotidea is a rubiaceae plant Hedyotis hedyotidea(DC.).Dried vine stem,Twelve batches of Chinese Herbal Pieces samples came from four traditional Chinese medicine decoction pieces companies in Hu′nan Province.To improve of thin layer chromatography(TLC)method for identification of Hedyotitis Hedyotidea.Add water content,total ash check items,according to the 2020 edition of Chinese Pharmacopoeia,the second method of moisture determination,determination of total ash content of samples by ash determination method,Average moisture,120% of the mean of total ash,control limit of moisture and total ash.Determine the content of water-soluble extract according to the extract determination method,the control limit of the extract was calculated by 80% of the average value of the extract.Results The improved TLC method was more efficient.The average water content of 12 batches of Hedyotis Hedyotidea samples was 12.67%,the recommended moisture limit was "not to exceed 15.0%";the mean value of total ash was 8.71%,it was recommended that the total ash limit be set at "not more than 11.0%";the mean value of water-soluble extract was 16.04%,it was recommended that the extract limit be set at "not less than 13.0%".Conclusion The water and total ash examination items were added,the TLC improved the examination efficiency,and the determination of the extract was more suitable to the clinical practice.It provides the basis for Hedyotis Hedyotidea Chinese Herbal Pieces quality standard improvement.
2022 Vol. 29 (11): 4-6 [Abstract] ( 47 ) HTML (1 KB)  PDF (642 KB)  ( 49 )
7 Influence of laparoscopic radical resection of colon cancer combined with postoperative intraperitoneal hyperthermic perfusion chemotherapy with Lobaplatin on different systems in patients with colon cancer
ZHANG Nan OU Jiwen ZHANG Qing
Objective To investigate the effect of laparoscopic radical resection of colon cancer combined with intraperitoneal hyperthermic perfusion chemotherapy of Lobaplatin on the safety of postoperative blood routine,liver function,renal function,and postoperative complications in patients with colon cancer.Methods A total of 100 patients with colon cancer admitted to the First People′s Hospital of Zhaoqing from January 2018 to January 2021 were retrospectively selected as the research objects.The patients who underwent laparoscopic radical colon cancer surgery combined with intraperitoneal hyperthermic perfusion chemotherapy with Lobaplatin were set as the observation group,and the patients who underwent laparoscopic radical colon cancer surgery alone were set as the control group,with 50 cases in each group.The blood routine,liver function,renal function,immune infection indexes,and postoperative recovery time of exhausting and defecation,food taking,hospital stay,and complication rate were compared between the two groups before and at 3 and 5 d after operation.Results Before operation and 3,5 d after operation,there were no significant differences in the levels of white blood cell(WBC),hemoglobin(HGB)or platelet(PLT)between the two groups(P＞0.05).At 3 and 5 d after operation,the levels of WBC and PLT of the two groups were higher than those before operation,and the HGB was lower than that before operation,with statistical significance(P＜0.05).Before operation and 3,5 d after operation,there were no significant differences in the level of alanine aminotransferase(ALT)or aspartate aminotransferase(AST)between the two groups(P＞0.05).There were no significant differences in AST at 3 d after operation and ALT at 5 d after operation in the two groups compared with those before operation(P＞0.05).The ALT at 3 d after operation and AST at 5 d after operation in the two groups were higher than those before operation,the differences were statistically significant(P＜0.05).Before operation and 3,5 d after operation,there was no significant difference in blood urea nitrogen(BUN)or serum creatinine(SCr)between the two groups(P＞0.05).There was no significant difference in the BUN or SCr of the two groups at 3 and 5 d after operation compared with those before operation(P＞0.05).Before operation and 5 d after operation,there was no significant difference in C-reactive protein(CRP)between the two groups(P＞0.05).Compared with the control group,the CRP in the observation group was higher than the control group at 3 d after operation,and the difference was statistically significant(P＜0.05).The CRP of the two groups at 3 and 5 d after the operation was higher than that before the operation,and the difference was statistically significant(P＜0.05).The recovery time of exhausting and defecation as well as taking food in observation group was longer than those in the control group,and the differences were statistically significant(P＜0.05).There were no significant differences between the two groups in postoperative complications and the number of rehospitalization one month after operation(P＞0.05).Conclusion Laparoscopic radical resection of colon cancer combined with Lobaplatin intraperitoneal hyperthermic perfusion chemotherapy is safe and feasible in the treatment of patients with colon cancer.It has litter influence on the blood system,liver function,and renal function,but did have effect on gastrointestinal system.It will not increase the incidence of postoperative complications.
2022 Vol. 29 (11): 7-11 [Abstract] ( 44 ) HTML (1 KB)  PDF (647 KB)  ( 12 )
12 Analysis of short tandem repeat heterozygosity in QF-PCR and research of comparison with Karyotyping
XU Chenxia WANG Degang ZHANG Yanfang ZHENG Guobing PENG Jianming▲
Objective Rapid diagnosis of prenatal samples was performed using QF-PCR to analyze multiple short tandem repeat(STR)marker heterozygosis and trisomy peak type.It provides a research basis for the design of STR loci in QF-PCR kits.Methods A total of 525 pregnant women who received interventional prenatal diagnosis in the Prenatal Diagnosis Center of Boai Hospital of Zhongshan from September 2020 to July 2021 were selected as the research subjects.QF-PCR technology was used for rapid diagnosis of 13,18,21 and sex chromosome aneuploid,and GeneMapper 5.0 software was used to view and record the STR typing results.Results The most heterozygote markers on chromosome 13,18,21 and X were D13S742,D18S386,D21S1414 and DXS8377,and the lowest heterozygosity was detected for D13S628,D18S391,D21S1433 and DXS981.A total of 31 cases(5.9%)of abnormal samples were found by QFPCR,including 27 cases of trisomy 21(19 cases),trisomy 18(6 cases)and trisomy 13(2 cases),1 case of X monomer,and 3 cases of other chromosomal abnormalities.In both trisomy 18 and trisomy 21,4 cases of bimodal STR labeled 2∶1 or 1∶2 were detected.All STR loci had single peak in 2 cases,and STR loci had only one double peak in 23 cases.Conclusion Compared with traditional Karyotyping,QF-PCR can diagnose the number abnormalities of common chromosome aneuploidy more quickly.QF-PCR has the advantages of simplicity,rapidity and high specificity.In the design of detection kits,STR loci with high heterozygosis for D13S742,D18S386 and D21S1414 should be selected as the interpretation of chromosome aneuploidy.
2022 Vol. 29 (11): 12-15 [Abstract] ( 47 ) HTML (1 KB)  PDF (705 KB)  ( 58 )
16 Synthesis of 4-nitro-1-naphthyl-β-D-galactopyranoside
DANG Jizheng1 YI Li2▲
Objective Design and synthesis of 4-nitro-1-naphthyl-β-D-galactopyranoside.Methods D-galactose reacted with sodium acetate and was obtained after esterification β-D-galactose pentaacetate.β-D-galactose pentaacetate was subjected to hydroacetic acid bromide solution,substituted with chromophore 4-nitro-1-naphthol,final hydrolysis to remove acetyl group,and then recrystallized to obtain the target compound.The target compounds were characterized by nuclear magnetic resonance(1H-NMR,13C-NMR)and high resolution mass spectrometry(ESI-HRMS).The selection of brominated reagents,hydroxyl acetylation reaction conditions and recrystallization conditions were optimized.Results The characterization results showed that the end product was compound 4-nitro-1-naphthyl-β-Dgalactopyranoside.In the preparation process,acetic acid solution of hydrogen bromide shall be selected as the brominating reagent,the reaction temperature should be 130 ℃and the reaction time should be 3 h,the ratio of recrystallized methanol/water shall be 3∶1.Conclusion The target compound 4-nitro-1-naphthyl-β-D-galactopyranoside was synthesized by this method and synthesis process is mild in reaction conditions and simple in operation.
2022 Vol. 29 (11): 16-19 [Abstract] ( 39 ) HTML (1 KB)  PDF (724 KB)  ( 92 )
20 Comparison of renal pelvic pressure,postoperative fever and effect of surgery between mini and standard-tract percutaneous nephrolithotomy:a meta-analysis
WAN Jinping LIN Jiangui LUO Liutao XU Zhenqiang▲
Objective To systematically evaluate the safety and efficacy of surgery between mini-tract percutaneous nephrolithotomy(MPCNL)and standard-tract percutaneous nephrolithotomy(SPCNL)in the treatment of upper urinary tract calculi.Methods Pubmed,Cochrane Library,Embase,Wanfang,CNKI and VIP databases were searched for randomized controlled trials related to percutaneous nephrolithotomy for patients with upper urinary calculi from the establishment of the database to December 1,2019.Two evaluators selected the trials according to the inclusion and exclusion criteria,and the data were extracted and analyzed by Revman 5.3 software for meta analysis.Results Four randomized controlled trials were included in this study,with a total of 375 patients.The results showed that the renal pelvis pressure(RPP)in MPCNL group was higher than that in SPCNL group,and the difference was statistically significant(MD=10.38,95%CI: 6.37-14.38, P＜0.000 01).The postoperative fever(POF)rate in MPCNL group was higher than that in SPCNL group,the difference was statistically significant(OR=2.43,95%CI: 1.39-4.27, P=0.002).There was no significant difference in the operative time between the MPCNL group and the SPCNL group(MD=5.69,95%CI:-4.54-15.91, P=0.28).There was no significant difference in stone clearing rate between MPCNL group and SPCNL group(OR=1.06,95%CI: 0.61-1.86, P=0.83).Conclusion Compared with SPCNL,MPCNL can increase intraoperative RPP and the patients′ POF rate.The two have similar surgical effect such as operation time and stone clearing rate.Therefore,the intraoperative detection of RPP by MPCNL is of great significance to ensure patient safety and reduce postoperative complications.
2022 Vol. 29 (11): 20-23 [Abstract] ( 46 ) HTML (1 KB)  PDF (951 KB)  ( 64 )
24 Effect comparison of different blood purification methods on renal function indexes in patients with chronic renal failure and uremia
YANG Bo
Objective To explore and analyze the effect of three different blood purification modes on the renal function indexes and nutritional status of patients with chronic renal failure and uremia,and to observe the adverse reactions during the application of different blood purification methods.Methods A total of 120 patients with chronic renal failure and uremia admitted to Liaoyang Central Hospital in Liaoning Province from April 2018 to April 2021 were selected as the research objects.The random number table method was used to divide them into group A with 40 cases,group B with 40 cases,and group C with 40 cases.Group A was given conventional hemodialysis treatment,group B was given high-flux hemodialysis treatment,group C was given hemodiafiltration treatment.The renal function indexes and nutrition-related indexes of patients of the three groups were compared,and the adverse reactions during the treatment period were observed.Results The levels of erythrocyte sedimentation rate(ESR),urine protein,and serum creatinine(SCr)after treatment in the three groups were lower than those before treatment,the blood urea nitrogen(BUN)levels in the three groups were higher than those before treatment,the levels of ESR,urine protein,and SCr in group B were lower than those of groups A and C,and the BUN level in group B was higher than that of groups A and C,the levels of ESR,urine protein,SCr and BUN in group A were higher than those in group C,with statistically significant differences(P＜0.05).The levels of total protein(TP),albumin(ALB),prealbumin(PA),and hemoglobin(Hb)after treatment in the three groups were higher than those before treatment,the levels of TP,ALB,PA and Hb in group B were higher than those in groups A and C,with statistically significant differences(P＜0.05).There was no statistical significance in the total incidence of adverse reactions among the three groups(P＞0.05).Conclusion The effect of high-flux hemodialysis in the treatment of chronic renal failure and uremia is significantly better than that of conventional hemodialysis and hemodiafiltration treatment.It not only effectively facilitates patients′ renal function indicators,but also helps to improve the patients′ nutritional status without increasing adverse reactions during the treatment period in high safety.
2022 Vol. 29 (11): 24-28 [Abstract] ( 50 ) HTML (1 KB)  PDF (619 KB)  ( 54 )
29 Research progress of relationship between Staphylococcus aureus surface protein and the biofilm
GUAN Xiaowen1 TIAN Yu1 WEI Lianhua2▲
Staphylococcus aureus and Staphylococcus epidermidis are the most important pathogens of biofilm related infection of indwelling medical devices. Staphylococcus aureus surface proteins Ebh,SasF,SasG,aggregation factor B(ClfB),biofilm associated protein(Bap)and fibronectin/fibrinogen binding protein are involved in the formation of biofilm matrix,respectively.This large number of proteins intervene in different stages of biofilm formation.Some proteins contribute to the accumulation of biofilm,while others mediate the primary attachment of biofilm surface.This paper reviews the role and regulatory mechanism of surface proteins in biofilm formation of Staphylococcus aureus,in order to provide a theoretical basis for the prevention and treatment of biofilm infection.
2022 Vol. 29 (11): 29-32 [Abstract] ( 48 ) HTML (1 KB)  PDF (449 KB)  ( 534 )
33 Clinical application value of neutrophil CD64 on the early diagnosis of infectious disease
TANG Mingxia FU Lifang YANG Jian▲
Early diagnosis of bacterial infection is helpful for rational use of antibiotics and effective reduction of resistant bacteria.The specificity and sensitivity of neutrophil CD64(nCD64)in the early diagnosis of bacterial infection were superior to white blood cell count(WBC),C-reactive protein(CRP),procalcitonin(PCT),interleukin-6(IL-6)and other traditional infection markers.nCD64 combined with CRP,PCT,IL-6 and other indicators has greater diagnostic value.This article reviews the application value of nCD64 in early diagnosis of infectious diseases.
2022 Vol. 29 (11): 33-36 [Abstract] ( 49 ) HTML (1 KB)  PDF (407 KB)  ( 158 )
37 Analysis of the expression level and diagnostic value of cyclic ribonucleic acid in non-small cell lung cancer tissues and adjacent tissues
LIU Chengying NONG Xueping▲
Objective To analyze the expression level and diagnostic value of circular ribonucleic acid(circRNA)in cancer and adjacent tissues of non-small cell lung cancer(NSCLC).Methods Pathological tissue samples of 12 NSCLC patients admitted to Jiangxi Chest Hospital from June 2020 to May 2021 were selected to screen out circRNA with significant difference in expression between cancer tissues and adjacent tissues.Volcanic map was made and cluster analysis was performed.Serum samples from 47 NSCLC patients and 47 healthy subjects were collected during the same period.The circRNA detection was performed on all patients,and receiver operating characteristic(ROC)curves were made to explore the diagnostic value of circRNA in NSCLC.Area under curve(AUC)was labeled to explore the correlation between serum circRNA expression level and clinical indicators.Results A total of 194 circrnas with obvious expression differences between cancer tissues and adjacent tissues were screened out,among which 121 showed up-regulation and 73 showed down-regulation.Volcanic map and cluster analysis results showed that circRNA could clearly distinguish NSCLC cancer tissues from adjacent tissues.There was no significant difference in circRNA expression level among NSCLC patients with different gender,age,smoking status,tumor differentiation,pathological type and cancer stage(P＞0.05).ROC curve results showed that the sensitivity,specificity and AUC of serum circRNA in the diagnosis of NSCLC were 82.98%,61.70% and 0.795 respectively.Conclusion The expression of circRNA in NSCLC cancer tissues and paracancerous tissues are significantly different,and the diagnosis of NSCLC by serum circRNA is more accurate,and the level of circRNA may reflect the disease to a certain extent.
2022 Vol. 29 (11): 37-39 [Abstract] ( 41 ) HTML (1 KB)  PDF (495 KB)  ( 27 )
40 Study on percutaneous immune effect of Clostridium difficile toxoid A mediated by microneedle
HE Jingrong ZHANG Yi DAI Wenxiu WANG Yueying FU Siwu▲
Objective The effect of two different immunization methods on the titer of Clostridium difficile toxoid A were compared to explore the transdermal immune effect of microneedle-mediated Clostridium difficile vaccine.Meth-ods After preparing Clostridium difficile toxoid A vaccine by dialysis,culture,purification,detoxification,twenty-four 18-22 g female BALB/c mice(SPF grade)were selected.They were divided into control group and observation group by random number table method,with 12 mice in each group.The control group was given intraperitoneal injection,and the observation group was immunized with microneedles percutaneously.At the 0,7th,14th,28th and 42th day of treatment,the titer levels of specific serum immunoglobulin G(IgG)and fecal secretory immunoglobulin A(IgA)were regularly detected.Finally,the actual immune effect of microneedle percutaneous immunization was evaluated by Clostridium difficile animal infection experiment.Results The serum antibody IgG titer of the two groups at the 42th day of treatment was higher than that at the 7th,14th and 28th day of treatment,and the difference was statistically significant(P＜0.05).There was no significant difference in the titer of serum antibody IgG between the two groups at the 14th,28th and 42th day of treatment(P＞0.05).The fecal IgA titer of the two groups at the 42th day of treatment was higher than that at the 7th,14th and 28th day of treatment,and the difference was statistically significant(P＜0.05).There was no significant difference in fecal IgA titer between the two groups at the 7th day(P＞0.05).The fecal IgA titer of the observation group at the 14th,28th and 42th day of treatment was higher than that of the control group in the same period,and the difference was statistically significant(P＜0.05).There was no death in both groups after challenge,and the percutaneous immune effect was good.After the mice were killed,compared with the mucosal epithelial ulcer and severe mucosal inflammation in the unimmunized mice,the inflammatory reactions in both groups were mild.Conclusion Microneedle-mediated Clostridium difficile toxin A vaccine has good mucosal immune effect.
2022 Vol. 29 (11): 40-44 [Abstract] ( 32 ) HTML (1 KB)  PDF (492 KB)  ( 53 )
45 Clinical effect of Dapagliflozin in the treatment of type 2 diabetic cardiomyopathy
CAO Chunli ZHANG Jing WU Shuqiong ZHANG Jingjing SONG Daofei▲
Objective To investigate the clinical efficacy and safety of Dapagliflozin in the treatment of type 2 diabetic cardiomyopathy.Methods A total of 80 patients with type 2 diabetic cardiomyopathy who were admitted to Hubei Provincial Hospital of Integrated Chinese and Western Medicine from March 2018 to December 2020 were selected as the research subjects.They were divided into treatment group and control group by random number table method,with 40 patients in each group.The control group received conventional medical treatment,and the treatment group was orally treated with Dagaglizin on the basis of the control group.Metabolic indexes(fasting blood glucose[FPG],2 hour postprandial blood glucose[2 h PG],glycated hemoglobin[HbA1c],total cholesterol[TC],triglyceride[TG],low-density lipoprotein[LDL-C)),blood pressure(systolic blood pressure[SBP],diastolic blood pressure[DBP])and cardiac function(left ventricle end-diastolic volume index[LVEDVI],left ventricular ejection fraction[LVEF])were compared between the two groups before and after treatment,and major adverse cardiac events were recorded.Results After treatment,the levels of FPG,2 h PG and HbA1c in the treatment group were lower than those in the control group,the differences were statistically significant(P＜0.05).After treatment,there were no significant differences in TC,TG and LDL-C levels between two groups(P＞0.05).After treatment,SBP and DBP in the treatment group were lower than those in the control group,the differences were statistically significant(P＜0.05).After treatment,the LVEDVI and LVEF of the treatment group were higher than those of the control group,the differences were statistically significant(P＜0.05).The total incidence of major adverse cardiac events in the treatment group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion In the treatment of type 2 diabetic cardiomyopathy,Dapagliflozin can not only effectively improve the metabolic indexes of patients such as blood glucose and blood pressure,but also improve the cardiac function of patients and reduce the occurrence of adverse cardiac events.The clinical treatment effect is significant,which is worthy of popularization and application.
2022 Vol. 29 (11): 45-48 [Abstract] ( 46 ) HTML (1 KB)  PDF (454 KB)  ( 35 )
49 Effect of oral administration of Xiaochaihu Decoction with Danggui Shaoyao Powder combined with acupuncture and moxibustion on thyroid function and immune factors in patients with Hashimoto thyroiditis
HUANG Tao ZHOU Yanhua ZHANG Mei
Objective To explore the effect of oral administration of Xiaochaihu Decoction with Danggui Shaoyao Powder combined with acupuncture and moxibustion in the treatment of Hashimoto thyroiditis(HT).Methods A total of 80 HT patients admitted to Yingtan City People′s Hospital from May 2020 to July 2021 were selected as the subjects,and they were divided into treatment group(n=40)and control group(n=40)according to random number table method.The control group was given Levothyroxine Sodium Tablets for routine treatment,and the treatment group was additionally given Xiaochaihu Decoction with Danggui Shaoyao Powder combined with acupuncture and moxibustion on the basis of the control group.The curative effect of traditional Chinese medicine syndrome,changes of thyroid function(free thyronine[FT3],free thyroxine[FT4],thyroid stimulating hormone[TSH],thyroid peroxidase antibody[TPO-AB],thyroglobulin antibody[TGAb]),peripheral blood T cell subsets and thyroid volume before and after treatment were compared between the two groups.Results The total effective rate of treatment group was higher than that of control group,the difference was statistically significant(P＜0.05).After treatment,TPO-AB and TGAb levels in the treatment group were lower than those in the control group,the differences were statistically significant(P＜0.05).There were no significant differences in FT3,FT4 and TSH levels between two groups before and after treatment(P＞0.05).After treatment,the peripheral blood CD3+,CD4+ and CD4+/CD8+ values in the treatment group were higher than those in the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in CD8+ between two groups before and after treatment(P＞0.05).After treatment,the thyroid volume of the treatment group was smaller than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Oral administration of Xiaochaihu decoction with Danggui Shaoyao powder combined with acupuncture and moxibustion can effectively improve the clinical symptoms of patients with HT,and it is beneficial to the outcomes of thyroid function and immune function.
2022 Vol. 29 (11): 49-51 [Abstract] ( 44 ) HTML (1 KB)  PDF (435 KB)  ( 75 )
52 Importance of joint capsule repair in artificial hip arthroplasty for elderly femoral neck fracture and its effect on postoperative joint function
JIANG Xike

Objective To investigate the effect of joint capsule repair on joint function after artificial hip arthroplasty in elderly patients with femoral neck fracture.Methods A total of 62 elderly patients with femoral neck fracture treated with artificial hip arthroplasty in Chenghai District People′s Hospital from January 2020 to April 2021 were selected and divided into study group and control group according to random number table method,with 31 cases in each group.The joint capsule was not repaired in operation in the control group,and the joint capsule was repaired in operation in the study group.The perioperative indexes of the two groups were compared,including bone morphogenetic protein-2(BMP-2),insulin-like growth factor-1(IGF-1),vascular endothelial growth factor(VEGF)at 1 d before operation and 10 d after operation,Harris score and complications at 1 d before operation and 7,14 and 28 d after operation.Results The intraoperative blood loss in the study group was more than that in the control group,the operation time was longer than that in the control group,and the time of hospitalization was shorter than that in the control group,first getting out of bed time was earlier than that in the control group,the differences were statistically significant(P＜0.05).There were no significant differences in the levels of VEGF,BMP-2 and IGF-1 between the two groups at 1 d before operation(P＞0.05).At 14 d after operation,the levels of VEGF,BMP-2 and IGF-1 in the study group were higher than those in the control group,the differences were statistically significant(P＜0.05).There were no significant differences in Harris scores between the two groups at 1 d before operation and 7 d after operation(P＞0.05).The Harris score of the study group was higher than that of the control group at 14 and 28 d after operation,the difference was statistically significant(P＜0.05).The total complication rate in the study group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion Joint capsule repair in artificial hip arthroplasty for elderly femoral neck fracture can effectively shorten the time of physical rehabilitation,promote the recovery of hip function and reduce the incidence of complications such as joint instability.However,it will also prolong the operation time of patients.Therefore,a scientific and reasonable operation plan should be formulated to avoid risks.
2022 Vol. 29 (11): 52-55 [Abstract] ( 43 ) HTML (1 KB)  PDF (461 KB)  ( 71 )
56 Analysis of influencing factors of chronic post-surgical pain after total hip replacement in the elderly
SHEN Weiming GAO Bing CHEN Jie
Objective To explore the influencing factors of chronic post-surgical pain(CPSP)after total hip arthroplasty in the elderly.Methods A total of 124 elderly patients who underwent total hip arthroplasty in Zhangzhou People′s Hospital from January 2015 to December 2020 were selected as the research objects.The occurrence of CPSP within 6 months after operation was evaluated by digital evaluation scale(NRS).The occurrence of CPSP was taken as the dependent variable,the American Association of Anesthesiologists(ASA)grade,operation time,postoperative analgesia,postoperative 24 h NRS score and general data were analyzed.Results Univariate analysis showed that age,body mass index(BMI),drinking history,operation time,hip joint starting time,postoperative analgesia mode,postoperative 24 h NRS score and deep venous thrombosis of lower extremities were related factors affecting CPSP.Multivariate analysis showed that the starting time of hip joint movement ≥3 d(β=-0.917, OR=0.629,95%CI=0.406-0.861)was the protective factor of CPSP,while age ≥70 years old(β=-0.728, OR=0.721,95%CI=0.593-0.832),BMI ≥28 kg/m2(β=0.754,OR=3.253,95%CI=2.061-8.092),operation time ＞2 h(β=1.734,OR=5.269,95%CI=2.381-12.962),deep vein thrombosis of lower extremities(β=1.208, OR=6.872,95%CI=4.724-12.736)and postoperative 24 h NRS score ＞3 points(β=1.820, OR=6.284,95%CI=2.593-14.872)were independent risk factors for CPSP(P＜0.05).Conclusion Age ＞70 years old,obesity,long operation time,postoperative deep venous thrombosis of lower extremities and postoperative 24 h NRS score ＞3 points are risk factors for CPSP after total hip arthroplasty in the elderly.Hip joint movement time ≥3 days is a protective factor for CPSP after total hip arthroplasty in the elderly.
2022 Vol. 29 (11): 56-59 [Abstract] ( 41 ) HTML (1 KB)  PDF (506 KB)  ( 104 )
60 Analysis of early rehabilitation effect after internal fixation of ankle fracture and its influencing factors
HUANG Yushun1 LI Enchao1 XUE Ziyao1 CHENG Biao2▲
Objective To investigate the early rehabilitation effect after internal fixation of ankle fracture,and to analyse the influencing factors.Methods A total of 60 patients underwent internal fixation of ankle fracture in Chung Yan Hing Memorial Hospital from January 2019 to January 2021 were selected as research objects,and the early rehabilitation training was performed within 12 weeks after surgery.After 12 months after surgery,the patients were divided into excellent ankle function group and poor ankle function group according to the American Orthopedic Foot and Ankle Society(AOFAS)ankle hindfoot score.The influence factors of early rehabilitation effect were analyzed by univariate analysis,and the multivariate logisitic regression was used to analyse the influencing factors of early rehabilitation effect.Results There were 42 patients(70.00%)with excellent ankle function and 18 patients(30.00%)with poor ankle function.Pain score,functional activity score and rear foot arrangement score were(38.45±1.12),(41.60±2.58)and(13.42±1.07)points.The univariate analysis showed that there were statistically significant differences between the proportion of patients with age ≥40 years,time from injury to operation ＞8 h,without persistence of functional exercise and postoperative complications between poor ankle function group and excellent ankle function group(P＜0.05).The multivariate analysis showed that age ≥40 years(β=0.274, OR=1.249,95%CI=1.022-1.615),time from injury to operation ＞8 h(β=0.285, OR=1.358,95%CI=1.097-1.704),without persistence of functional exercise(β=0.347, OR=1.472,95%CI=1.135-1.890)and postoperative complications(β=0.382, OR=1.375,95%CI=1.119-1.762)were the independent risk factors for poor ankle function in early rehabilitation(P＜0.05).Conclusion The early rehabilitation effect after internal fixation of ankle fracture was better,and there were many influencing factors,so the targeted measures should be taken to ensure early rehabilitation effect.
2022 Vol. 29 (11): 60-63 [Abstract] ( 50 ) HTML (1 KB)  PDF (457 KB)  ( 62 )
64 Effect of Bacillus Subtilis combined with traditional Chinese medicine immersion(fumigation)on neonatal jaundice
ZHONG Lang1 LI Junwu1 YU Zhixin1 LIU Mengqi1 LUO Sijing2
Objective To investigate the clinical effect of Bacillus Subtilis combined with traditional Chinese medicine immersion in the treatment of neonatal jaundice.Methods A total of 60 cases of neonatal jaundice patients admitted to Pingxiang Maternal and Child Health Hospital from July 2020 to July 2021 were selected as research objects.According to random lottery method,they were divided into control group and observation group,with 30 cases in each group.Control group used Bacillus Subtilis,and the observation group used Bacillus Subtilis combined with Chinese medicine immersion(fumigation)combination therapy.The effect of different treatment schemes on children were compared.Results Before treatment(0 h≤birth time＜24 h),there was no significant difference in total serum bilirubin(TSB)level between two groups(P＞0.05).The TSB level of observation group was lower than that of control group at 1 d(24 h≤birth time＜48 h),2 d(48 h≤birth time＜72 h)and 3 d(72 h≤birth time＜96 h)after medication,the difference was statistically significant(P＜0.05).There was no significant difference in the readmission rate between the two groups(P＞0.05).There was no statistically difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The treatment of neonatal jaundice with Bacillus Subtilis combined with traditional Chinese medicine immersion can slow down the rise or even decrease of jaundice in peak period,improve the therapeutic effect and reduce the phototherapy rate.
2022 Vol. 29 (11): 64-66 [Abstract] ( 39 ) HTML (1 KB)  PDF (533 KB)  ( 91 )
67 Effect of anticoagulant therapy on prethrombotic state and pregnancy outcome in patients with recurrent abortion and increased uterine artery resistance index
YUAN Jinlan1 LUO Qiongxiu2
Objective To investigate the effect of anticoagulant therapy on prethrombotic state and pregnancy outcome in patients with recurrent abortion and increased uterine artery resistance index.Methods A total of 120 patients with recurrent miscarriage with increased uterine artery resistance index admitted to Ji′an Maternity and Child Health Hospital from January to December 2020 were selected as research objects.They were divided into observation group and control group according to random number table method,with 60 cases in each group,all patients began to use drugs after vaginal color Doppler ultrasound prompts early intrauterine pregnancy(within 5 weeks of pregnancy).The control group was given Dydrogesterone Tablets and Vitamin E Capsules.The observation group was treated with Low-molecular-weight Heparin Calcium on the basis of the control group.The changes of resistance index(RI),prethrombotic state indexes(D-dimer[DD],thrombin time[TT],antithrombin Ⅲ[ATⅢ]activity)and pregnancy activity rate were compared between the two groups before and after treatment.Results The RI score of the observation group after treatment was lower than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,DD in the observation group was lower than that in the control group,and TT and ATⅢwere higher than those in the control group,and the differences were statistically significant(P＜0.05).The live birth rate of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Anticoagulant therapy can effectively reduce RI,improve prethrombotic state and pregnancy outcome in patients with recurrent abortion and increased uterine artery resistance index.
2022 Vol. 29 (11): 67-70 [Abstract] ( 36 ) HTML (1 KB)  PDF (569 KB)  ( 9 )
71 Application of manual compression to control bleeding in the operation of central placenta previa
ZENG Zhen ZHANG Guilian XIAO Cheng
Objective To explore the application value of manual compression to control bleeding in the operation of central placenta previa.Methods A total of 100 patients with central placenta previa in the Department of Obstetrics of Ganzhou Maternal and Child Health Hospital from January 2019 to December 2020 were selected as the research object,they were divided into the control group(50 cases)and the observation group(50 cases)according to the random number table method.The control group received routine hemostatic surgery and Oxytocin injection,while the observation group received manual compression to control bleeding.The hemostatic effect and neonatal condition of the two groups were compared.Results The amount of intraoperative bleeding,the amount of bleeding 2 h after operation,the amount of blood transfusion and the amount of Cabetoxin in the observation group were less than those in the control group,and the operation time in the observation group was shorter than that in the control group,the differences were statistically significant(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).The Apgar scores of newborns in the observation group at 1,5 and 10 min of birth were significantly higher than those in the control group,the differences were statistically significant(P＜0.05).Conclusion In the operation of central placenta previa,the effect of manual compression to control bleeding is remarkable,which can ensure the safe and smooth operation,improve the safety of pregnant women and newborns,and has high popularization and application value.
2022 Vol. 29 (11): 71-73 [Abstract] ( 37 ) HTML (1 KB)  PDF (566 KB)  ( 107 )
74 Efficacy and safety analysis of umbilical vein catheterization for premature and low birth weight infants
WU Weijie
Objective To investigate the efficacy and safety of umbilical vein catheterization(UVC)for premature and low birth weight infants.Methods From July 2018 to October 2021,50 cases of premature and low birth weight infants admitted to Yunfu Maternal and Child Health Hospital in Guangdong Province were selected as the research objects.They were divided into the observation group and the control group by random number table method,with 25 cases in each group.The control group received conventional peripheral central venous catheterization(PICC)support treatment,and the observation group received UVC support treatment.The changes of nutritional indexes,the success rate of onetime puncture,the rate of unplanned extubation,the weight gain and the depth of catheterization in the two groups were compared before and after treatment,and the incidence of adverse events in the two groups were counted.Results The plasma albumin level of the two groups after treatment were higher than those before treatment,and the plasma albumin level of the observation group after treatment was higher than that of the control group,the differences were statistically significant(P＜0.05).The success rate of one-time puncture and weight gain in the observation group after treatment were higher than those in the control group,and the unplanned extubation rate,depth of catheterization and the incidence of adverse events in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion The implementation of UVC support treatment for premature and low birth weight infants can effectively improve the treatment effect and promote the recovery of signs,and the risk of adverse events caused by UVC is lower.Compared with conventional PICC,its effectiveness and safety are higher.
2022 Vol. 29 (11): 74-76 [Abstract] ( 40 ) HTML (1 KB)  PDF (552 KB)  ( 138 )
77 Influence of combined rehabilitation training based on the concept of "international classification of functioning,disability and health" on developmental behavior of children with low vision
LIN Liangfeng1 WANG Yongfen1 YU Yang2 YE Wenwen2 SHI Wenjian2 SU Caihui1
Objective To investigate the influence of sensory integration and residual visual perception combined rehabilitation training on the developmental behavior of children with low vision based on the concept of "international classification of functioning,disability and health".Methods A total of 60 children with low vision screened in Quanzhou Blind School from May 2020 to May 2021 were selected as research objects,they were divided into the observation group(30 cases)and the control group(30 cases)according to the random number table method.The children in the observation group received combined rehabilitation training of sensory integration and residual visual perception while using various visual aids,while the children in the control group only used visual aids.All children were assessed by children sensory integrative function scale(SIFS)and Gesell developmental diagnosis scale(GDDS)before and after training.The SIFS and GDDS scores of the two groups before and after training were statistically analyzed by paired sample t-test.Results There were no significant differences in the scores of vestibular sensation,tactile defense,ontological sense,learning ability,adaptive behavior,grand motor,fine motor,language and language and personal-social behavior between the two groups before training(P＞0.05).After 6 months of training,the scores of vestibular sensation,tactile defense,ontological sense,learning ability,adaptive behavior,grand motor,fine motor,language and language and personal-social behavior in the observation group were higher than those in the control group,with statistically significant differences(P＜0.05).Conclusion Sensory integration and residual visual perception combined with rehabilitation training can improve the developmental behavior of children with low vision.
2022 Vol. 29 (11): 77-80 [Abstract] ( 47 ) HTML (1 KB)  PDF  (0 KB)  ( 13 )
81 Effect and safety of Vinblastine Sustained Release Capsules in the treatment of non-arteritic anterior ischemic optic neuropathy
PAN Yiyi WANG Jing TANG Lili XIA Yanzhu
Objective To study the effects and safety of Vinblastine Sustained Release Capsules in the treatment of non-arteritic anterior ischemic optic neuropathy(NAION).Methods A total of 44 NAION patients(44 eyes)treated from January 2017 to January 2021 in Sinqi Ophthalmology Hospital of Shenyang City and Shenyang Fourth People′s Hospital were investigated.According to registration time,they were divided into the control group and the study group according to the treatment time,there were 22 cases and 22 eyes in both groups.The patients in the control group(from January 2017 to December 2019)were treated with conventional drugs,and the patients in the study group( from January 2020 to January 2021)were treated with Vinblastine Sustained Release Capsules on the basis of the control group.The visual acuity,average visual field defect,electrophysiological indexes and morphological indexes of the two groups were observed before and after treatment.Results There were no significant difference in best corrected visual acuity(BCVA),average visual field defect,amplitude and latency of pattern visual evoked potential(PVEP),thickness of retinal nerve fiber layer(RNFL)and thickness of retinal ganglion cell complex(GCC)between the two groups before treatment(P＞0.05).There were no significant difference in PVEP amplitude and latency between before treatment and after treatment in the control group(P＞0.05).The average visual acuity,average visual field defect,RNFL and GCC of the two groups after treatment were lower than those before treatment,the average visual acuity,visual field defect,PVEP amplitude and latency of the study group after treatment were lower than those of the control group,and the PVEP amplitude and latency of the study group after treatment were lower than those before treatment,the differences were statistically significant(P＜0.05).Conclusion Vinblastine Sustained Release Capsules has a good overall effect in NAION patients.It can improve patients′ vision and reduce the average defect of visual field.It is helpful for patients with optic nerve injury and is worthy of application.
2022 Vol. 29 (11): 81-84 [Abstract] ( 41 ) HTML (1 KB)  PDF (465 KB)  ( 65 )
85 Clinical effect of Montelukast combined with Budesonide in the treatment of secretory otitis media
ZHANG Cheng
Objective To explore the clinical effect of Montelukast combined with Budesonide in the treatment of secretory otitis media.Methods A total of 142 patients with secretory otitis media treated in Hu′nan Aerospace Hospital from January 2018 to January 2021 were selected,and they were divided into the control group(71 cases)and the observation group(71 cases)according to the random number table method.The patients in the two groups were given routine treatment,the patients in the control group were treated with Budesonide,and the patients in the observation group were treated with Montelukast on the basis of the control group.The clinical efficacy,tympanic pressure,speech frequency and air conduction hearing threshold of the two groups were observed,and the levels of serum paraoxonase-1(PON1),lipid hydroperoxide(LOOH)and transforming growth factor-β1(TGF-β1),transforming growth factor-β2（TGF-β2),serum interleukin-1β(IL-1β),interleukin-8(IL-8),procalcitonin(PCT)and tumor necrosis factor-α(TNF-α)were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,and the recurrence rate of the observation group was lower than that of the control group,the differences were statistically significant(P＜0.05).The tympanic pressure and speech frequency air conduction hearing threshold after treatment of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).The level of PON1 after treatment of the observation group was higher than that of the control group,and the level of LOOH after treatment of the observation group was lower than that of the control group,the differences were statistically significant(P＜0.05).The levels of TGF-β1 and TGF-β2 after treatment in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).The levels of IL-1β,IL-8,PCT and TNF-α after treatment in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Montelukast combined with Budesonide in the treatment of secretory otitis media can effectively improve its curative effect,reduce the recurrence rate,improve the symptoms and signs of patients,increase the level of serum PON1 and reduce the level of LOOH,TGF-β1 and TGF-β2,the clinical effect is good,and it is worthy of popularization and application.
2022 Vol. 29 (11): 85-88 [Abstract] ( 34 ) HTML (1 KB)  PDF (491 KB)  ( 66 )
89 Effect of adenoidectomy combined with tympanic membrane incision and indwelling catheter in the surgical treatment of children with adenoid hypertrophy complicated with secretory otitis media
QIN Xuejun TAN Yumin▲ ZHOU Cheng
Objective To study the effect of of adenoidectomy combined with tympanic membrane incision and indwelling catheter in the surgical treatment of children with adenoid hypertrophy complicated with secretory otitis media.Methods A total of 110 children with adenoid hypertrophy complicated with secretory otitis media treated in the Department of Otolaryngology of the First People′s Hospital of Hechi City from January 2018 to June 2020 were selected as the research objects.They were divided into the observation group(55 cases)and the control group(55 cases)by random number table method.The children in the observation group were treated with adenoidectomy combined with tympanic membrane incision and drainage,and the children in the control group were treated with adenoidectomy combined with tympanic membrane incision and indwelling catheter.The treatment effect,the incidence rate of complication,and the recurrence rate of the two groups of children were compared.Results The total effective rate of the observation group was 90.91%,compared with 87.27% of the control group,the difference was not statistically significant(P＞0.05).The incidence rate of complications in the observation group was 29.09%,which was higher than that of the control group accounting for 9.09%,the difference was statistically significant(P＜0.05).Follow-up for 6 months,the recurrence rate of children in the observation group was 7.27%,which was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Adenoidectomy combined with tympanic membrane incision and drainage or combined tympanic membrane incision and indwelling catheter have good surgical effects on children with adenoid hypertrophy complicated with secretory otitis media,but children with tympanic membrane incision and catheterization have fewer complications and lower recurrence rate,which is worthy of promotion.
2022 Vol. 29 (11): 89-92 [Abstract] ( 40 ) HTML (1 KB)  PDF (466 KB)  ( 56 )
93 Correlation between serological indicators and pathological staging in patients with primary biliary cholangitis and prognostic factors of primary biliary cholangitis
AO Qinfang1 SUN Huabao1 ZHANG Ping2 GAN Min1
Objective To investigate the correlation between serological indicators and pathological staging in patients with primary biliary cholangitis(PBC)and prognostic factors of PBC.Methods Forty-six patients with PBC(PBC group)admitted to Nanchang Ninth Hospital,and 50 patients without liver disease(control group)were selected between April 2015 and October 2020.Serum total bilirubin(TBil),total bile acid(TBA),cholinesterase(CHE),alkaline phosphatase(ALP),γ-glutamyl transpeptidase(γ-GT),alanine aminotransferase(ALT),aspartate aminotransferase(AST),albumin(ALB),globulin(GLB)and immunological indicators(anti-nuclear antibody[ANA],anti-mitochondrial antibody[AMA],anti-mitochondrial antibody M2[AMA-M2],anti-gp210 antibody[gp210],anti-sp100 antibody[sp100])in the two groups were detected,and the correlation between the above indexes and pathological stages were analyzed,and the risk factors affecting the prognosis of PBC were discussed.Results The levels of TBil,TBA,CHE,ALP,γ-GT,ALT,AST,ALB,and GLB in the PBC group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The levels of TBil,γ-GT and GLB in stage Ⅲwere higher than those in stage Ⅰ,and the differences were statistically significant(P＜0.05).The levels of ALP and AST in stage Ⅱand stage Ⅲwere higher than those in stage Ⅰ,and the differences were statistically significant(P＜0.05).The levels of CHE and ALB in stage Ⅱand stage Ⅲwere lower than those in stage Ⅰ,and the differences were statistically significant(P＜0.05).The level of ALP in stage Ⅲwas higher than that in stageⅡ,and the difference was statistically significant(P＜0.05).There were statistically significant differences in the positive detection rate of AMA-M2 among patients with PBC in different pathological stages(P＜0.05).Univariate analysis showed that age,TBil,γ-GT,and ALB were related to the prognosis of patients with PBC(P＜0.05).Multivariate analysis found that TBil(β=0.031, OR=1.031,95%CI=1.015-1.048)was an independent prognostic factor of patients with PBC,and ALB(β=0.182, OR=0.834,95%CI=0.756-0.919)was a protective factor of patients′ prognosis with PBC(P＜0.05).Conclusion The levels of TBil,TBA,CHE,ALP,γ-GT,ALT,AST,ALB and GLB,the positive detection rates of ANA,AMA,AMA-M2,and sp100 are different in patients with PBC in different pathological stages.TBil and ALB are factors influencing the prognosis of patients with PBC.Clinically,the detection of related serological indicators can assist in judging the pathological stage and prognosis,thereby providing a basis for treatment.
2022 Vol. 29 (11): 93-97 [Abstract] ( 38 ) HTML (1 KB)  PDF (464 KB)  ( 149 )
98 Clinical significance of combined detection of serum amyloid protein,hypersensitive C-reactive protein and procalcitonin in the diagnosis of primary nephrotic syndrome in children
TANG Min
Objective To investigate the correlation of serum amyloid protein(SAA),hypersensitive C-reactive protein(HS-CRP)and procalcitonin(PCT)levels in children with Primary Nephrotic Syndrome(PNS).Methods A total of 60 children with primary nephrotic syndrome admitted to Fuzhou First People′s Hospital from May 2019 to November 2020 were selected as the observation group,and 60 healthy children in the same hospital during the same period were selected as the control group.The levels of SAA,HS-CRP and PCT were compared between the two groups.Results The levels of SAA,Hs-CRP and PCT in PNS children were higher than those in control group,and the differences were statistically significant(P＜0.05). Pearson correlation analysis of SAA,Hs-CRP and PCT in PNS children showed that PCT level was positively correlated with SAA,hs-CRP level(P＜0.05).Hs-CRP level was positively correlated with SAA level(P＜0.05).Conclusion SAA,HS-CRP and PCT can help the diagnosis of primary nephrotic syndrome in children to a certain extent.
2022 Vol. 29 (11): 98-100 [Abstract] ( 37 ) HTML (1 KB)  PDF (447 KB)  ( 25 )
101 Diagnostic value of serum cystatin C and β2-microglobulin in early renal injury of diabetes
YANG Liping CHEN Jinling CHEN Dongling CHEN Zhenfen LI Yangyang
Objective To explore the diagnostic value of serum cystatin C(CysC)and β2-microglobulin(β2-MG)for early renal injury in diabetes.Methods A total of 60 cases of early diabetic nephropathy in Yangjiang People′s Hospital from January 2020 to July 2021 were selected as renal injury group，in the same period,30 patients with simple diabetes mellitus(DM)were selected as DM group and 30 healthy persons were selected as control group.Serum CysC and β2-mg level in the three groups were detected,the diagnostic value of single level detection and combined detection of β2-MG level in early diabetic kidney injury was analyzed.Results The levels of serum CysC and β2-mg in renal injury group were higher than those in DM group and control group,and the differences were statistically significant.Serum CysC was positive in 48 cases and negative in 52 cases,β2-mg was positive in 45 cases and negative in 53 cases.CysC and β2-mg combined test were positive in 56 cases and negative in 57 cases.The sensitivity and accuracy of the combined detection of serum CysC and β2-MG were higher than that of β2-mg alone and seram CysC alone,and the differences were statistically significant(P＜0.05).The sensitivity and accuracy of β2-MG combined detection for early diabetic nephropathy were higher than those of β2-mg detected alone and seram CysC were detected alone,and the differences were statistically significant(P＜0.05).Conclusion Serum CysC and β2-MG are highly expressed in early diabetic kidney injury.The combined test has high sensitivity and specificity for early diagnosis of DN,and attention should be paid.
2022 Vol. 29 (11): 101-103 [Abstract] ( 43 ) HTML (1 KB)  PDF (809 KB)  ( 42 )
104 Investigation and analysis of the awareness and learning willingness of residents of Mudanjiang city on emerging infectious diseases
NA Zhimin1 CUI Xingang2 SONG Weidong3 ZHAO Xucheng1 LIU Hongxia1 HU Feng4 WANG Hong1 QIN Zhenzhen1
Objective To understand the awareness and willingness to learn about new infectious diseases among the residents of Mudanjiang City,so as to provide an effective basis for formulating relevant strategies in future.Methods From September to November 2020,a number of communities in different administrative districts and counties of Mudanjiang City were selected by convenient sampling.Questionnaire star software was used to be filled in by the respondents themselves.SPSS software was used to analyze the sorted data with the corresponding statistical methods.Results There were 66.66%,77.71% and 96.27% of the population were willing to know the knowledge of emerging infectious diseases,willing to participate in propaganda activities and thought that the propaganda activities were effective,respectively.The willingness of the population to learn the knowledge of the prevention and avoidance of emerging infectious diseases was higher than the willingness to learn the characteristics and hazards of the disease,selfrescue and mutual rescue,and the differences were statistically significant(P＜0.001).The problems of low public participation in emerging infectious disease education activities were higher than that of single form,not novel,and incomplete infrastructure,and the differences were statistically significant(P＜0.001).The awareness rates of basic knowledge,typical clinical manifestations and disease recovery of emerging infectious diseases were 80.91%,95.15% and 87.10%,respectively.There was no statistical significance in cognition of emerging infectious diseases among different age groups(P＞0.05).There was no statistical significance in the cognition of emerging infectious diseases among medical and related workers compared with those in enterprises and public institutions(P＞0.05).The cognition of medical and related workers on all aspects of emerging infectious diseases was higher than that of students,and the cognition of basic knowledge and disease recovery of emerging infectious diseases was higher than that of other professions,and the differences were statistically significant(P＜0.05).The staff of enterprises and institutions had higher clinical manifestations of emerging infectious diseases and disease recovery than students,the difference was statistically significant(P＜0.008).The knowledge cognition of enterprise and public institution personnel after disease recovery was higher than that of other professions,and the difference was statistically significant(P＜0.001).Urban residents had higher basic knowledge and cognition of emerging infectious diseases than rural residents,and the difference was statistically significant(P＜0.001).Conclusion People in Mudanjiang City are willing to learn and participate in new infectious diseases,but rural residents and lower-age people have a slightly lower awareness.For this,targeted activity strategies should be developed.
2022 Vol. 29 (11): 104-108 [Abstract] ( 39 ) HTML (1 KB)  PDF (621 KB)  ( 33 )
109 A risk assessment tool for central venous catheter infection in intensive care unit patients was established based on the Delphi method
HUANG Huayong1 LUO Qin1 HU Yajing1 LUO Wuchun2 LIAO Li1▲
Objective To establish central venous catheter infection risk assessment tool for measuring of Chinese intensive care unit(ICU)patients with central venous catheter infection risk.Methods Using the Delphi method,Risk Scoring System for Central Venous Catheterization Associated Bloodstream Infections for reference,with nursing safety and risk management theory as the framework,the expert consultation questionnaire was formed on the basis of review relevant literature.Twenty-five experts were selected for two rounds of expert consultation,and the items of the scale were screened to form the final risk assessment tool for the patients in ICU.Results The expert′s positivity was high and the response rates of the two-round consultation were 83.3% and 100%,the coefficient of the expert′s authorities Cr were 0.89 and 0.88,after the two-round consultation,Kendall′s W was 0.331(P＜0.001).Finally,ICU patients central venous catheter infection risk assessment tool included 4 first-level indicators,19 second-level indicators.Conclusion The reliability and authority of ICU patients central venous catheter infection risk assessment tool established based on the Delphi method is relatively high.It can provide a reference for clinical nurses to evaluate ICU patients central venous catheter infection risk and lays a foundation for testing the reliability and validity and evaluating the predictive ability of the scale.
2022 Vol. 29 (11): 109-113 [Abstract] ( 43 ) HTML (1 KB)  PDF (603 KB)  ( 179 )
114 Infection distribution and drug sensitivity analysis of 583 cases of Streptococcus agalactiae
CHEN Qing CHENG Feng QIU Huahong
Objective To analyze the infection distribution and drug susceptibility of 583 cases of Streptococcus agalactiae(GBS)in order to provide clinical reference.Methods Retrospectively analyze the distribution of 583 GBS-positive specimens isolated from Fujian Maternal and Child Health Hospital from January 1,2019 to December 31,2020 and the results of the drug sensitivity test.Results The source and distribution of 583 GBS positive specimens were mainly genital secretions,followed by blood.Obstetrics is the most widely distributed department,followed by gynecology and neonatology.The drug sensitivity results showed that the sensitivity rate of 583 strains of GBS to 6 kinds of antibiotics,including Vancomycin,Penicillin,Ampicillin,Tigecycline,Quinupristin/Dafopristin,and Linezolid,was 100.00%.There was no intermediary or resistance.Drug resistance rates to Levofloxacin,Moxifloxacin,Erythromycin,Clindamycin,and Tetracycline were 28.0%,27.4%,58.3%,49.1%,75.6%.Conclusion Infection in pregnant women during the perinatal period can lead to adverse pregnancy outcomes.The screening of GBS during pregnancy and the preventive application of antibiotics during delivery of women in the third trimester can effectively improve pregnancy outcomes.
2022 Vol. 29 (11): 114-116 [Abstract] ( 38 ) HTML (1 KB)  PDF (537 KB)  ( 32 )
117 Study on occupational stress adjustment ability and influencing factors of pediatric hematological oncology nurses
HUANG Ying1 GUO Shufang2
Objective To investigate the occupational stress adjustment ability of nurses specializing in children′s hematology and tumors,and to explore its influence factors.Methods A total of 40 pediatric hematological oncology nurses in Fujian Children′s Hospital from January to December 2020 were selected by random number table method as the research objects.The stress quotient(AQ)scale and the Chinese Nurses Work Stress Source Scale were used to evaluate the occupational stress level and adjustment ability of nurses,and the influencing factors were analyzed.Results The average score of pressure level scale was(95.53±8.95)and the average score of pressure adjustment ability was(16.51±1.85).Among them,15 cases(37.50%)had difficulty in coping,20 cases(50.0%)had moderate coping,and 5 cases(12.50%)had free coping.Univariate results showed that there was no statistical significance in the adjustment ability of occupational stress among nurses of pediatric hematology oncology department with different gender,age and employment mode(P＞0.05).There were statistically significant differences in occupational stress adjustment ability among children hematology oncology nurses with different educational background,nursing age and professional title(P＜0.05).Multivariate analysis showed that low educational background(β=1.973, OR=7.982,95%CI=6.313-8.493),low nursing age(β=1.495, OR=6.791,95%CI=6.312-7.326),low professional title(β=1.213, OR=5.457,95%CI=4.698-7.132)was independent risk factors for occupational stress adjustment ability of pediatric hematology oncology nurses(P＜0.05).Conclusion The general pressure of nurses specializing in hematology and tumors in children comes from social factors,occupational factors,specialist technical pressures,specialties of children,etc.Generally,the higher the nursing age and the higher the educational background of nurses,the better the ability to adjust to occupational stress.
2022 Vol. 29 (11): 117-119 [Abstract] ( 46 ) HTML (1 KB)  PDF (834 KB)  ( 146 )
120 Application effect of six Sigma management method in quality control of pediatric intensive care
SONG Xiayan RONG Guansong WEI Xiaojuan
Objective To explore the application effect of six Sigma management method in the quality control of pediatric intensive care.Methods A total of 90 children with severe diseases admitted to Jiangxi Children′s Hospital from January 2019 to December 2020 were selected as the research objects,and they were divided into control group(45 cases)and observation group(45 cases)according to the time of admission.Patients in the control group were admitted from January to December 2019 and received conventional nursing management.The observation group was admitted from January to December 2020,and six Sigma management method was adopted.The nursing satisfaction,clinical nursing quality control results and the total incidence of adverse nursing events were compared between the two groups.Results The family satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).All nursing quality control scores in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The total incidence of adverse nursing events in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion In the quality control of pediatric critical care,the implementation of six Sigma management method can effectively promote the improvement of pediatric critical care quality,then promote the reduction of adverse nursing events during nursing work,improve the satisfaction of children′s family members,and has the value of clinical application.
2022 Vol. 29 (11): 120-123 [Abstract] ( 37 ) HTML (1 KB)  PDF (475 KB)  ( 69 )
124 Practical effect of automated construction of outpatient pharmacy in Heyuan People′s Hospital
GAO Zhiyong FAN Weijin ZHU Qingzeng HUANG Donghui LI Xiang
Objective To explore the construction and practical effect of outpatient pharmacy automation in Heyuan People′s Hospital.Methods From June 2019 to May 2020(before the automation of outpatient pharmacy),250 prescriptions data in manual general pharmacy of Heyuan People′s Hospital were selected as the control group,250 prescription data from June 2020 to May 2021(after outpatient pharmacy automation)were selected as the study group.The pharmacy prescription processing speed,storage capacity,drug management items,drug collection time and dispensing error rate were compared between the two groups.Results The prescription processing speed of the study group was faster than that of the control group,drug storage capacity was higher than that of the control group,the differences were statistically significant(P＜0.05).The time of drug taking in the study group was shorter than that in the control group,and the error rate of drug dispensing was lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion The construction of automatic information system in outpatient pharmacy can effectively reduce the occurrence of pure manual operations errors,faults and other events,rationally use the automatic system,improve the quality of pharmaceutical care,reduce the labor intensity of employees,and improve patient satisfaction,which is worthy of promotion.
2022 Vol. 29 (11): 124-126 [Abstract] ( 39 ) HTML (1 KB)  PDF (466 KB)  ( 90 )
127 Evaluation of the operational efficiency of hospital clinical departments based on K-means clustering algorithm
HE Yulin
With the advancement of China′s medical and health system reform,public hospitals have gradually transformed from a traditional expansion business model to a connotative business model.Under the severe situation of constantly changing external environment,public hospitals need to change their management thinking,strengthen internal operation management,and further improve the efficiency of operation management.Hospital operating efficiency is an important part of the core competitiveness of public hospitals,and its improvement depends on the improvement of the operating efficiency of clinical departments.How to make an objective and true evaluation of the work of clinical departments through the presentation of operational efficiency data is also the focus and difficulty in the management process.This article uses the operational efficiency evaluation indicators in the three-level public hospital performance evaluation index system as a reference basis,according to the actual situation of the hospital,explores the establishment of easy-to-extract data and good general clinical department operation efficiency evaluation indicators.Using K-means clustering to explore and analyze,evaluate the operating efficiency indicators of 31 clinical departments in the hospital,and the results are divided into four categories: high,second-high,second-low,and low operating efficiency.The evaluation effect is helpful for the hospital to find the deficiencies of the clinical departments,and also provides a reference for the hospital to allocate medical resources and evaluate the performance of the clinical departments.
2022 Vol. 29 (11): 127-131 [Abstract] ( 42 ) HTML (1 KB)  PDF (564 KB)  ( 47 )
132 Construction and implementation of clinical teaching bases outside Beijing for specialized nurses in the department of anesthesiology
YAN Jinxiu LIU Lingyu XU Qingqin ZHAO Na ZHANG Zhiwei YU Zhifeng
In order to implement the spirit of Opinions on Strengthening and Improving Anesthesia Care jointly issued by the National Health Commission and seven ministries,effectively improve the professional and technical level of anesthesia specialty nurses,dig the national advantageous resources,improve the quality of specialty training and promote homogeneous development,in 2020,the Chinese Nursing Association started the evaluation of clinical teaching bases outside Beijing for specialized nurses in the department of anesthesiology.The First Affiliated Hospital of Nanchang University(hereinafter referred to as "the hospital")has successfully passed the preliminary evaluation and reevaluation and became the first batch of clinical teaching bases outside Beijing for specialized nurses in the department of anesthesiology of the Chinese Nursing Society.This paper summarized the experience of base construction and implementation from the aspects of base application,management system,teacher audit and training,training scheme,etc.It is proposed that strengthening teacher training and teaching evaluation is the focus of base construction in the hospital.Moreover,it will provide reference for better construction of clinical teaching base outside Beijing for specialized nurses in anesthesiology department.
2022 Vol. 29 (11): 132-134 [Abstract] ( 36 ) HTML (1 KB)  PDF (545 KB)  ( 60 )
135 Application effect of knowledge,belief and action mode in health education of elderly patients with H type hypertension
HU Liping ZHU Mingli WANG Jiali LIAO Chunmei
Objective To explore the application effect of knowledge,belief and action mode in the health education of elderly patients with H type hypertension.Methods A total of 100 H type hypertension patients admitted to Department of General Medicine of Guilin People′s Hospital from January 2020 to December 2020 were selected as the research objects,and divided into control group and observation group by lottery,with 50 patients in each group.The control group adopted routine health education,and the observation group adopted the health education mode of knowledge,belief and action.Blood pressure level,health knowledge awareness rate,medication compliance,blood pressure control rate and quality of life score were compared between the two groups.Results Systolic pressure and diastolic pressure in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The health knowledge awareness rate,medication compliance and blood pressure control compliance rate in observation group were higher than those in control group,and the differences were statistically significant(P＜0.05).The quality of life score of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion In the health education of elderly patients with H type hypertension,the mode of knowledge,belief and action can not only improve the mastery of disease knowledge of patients,but also improve the level of blood pressure of patients,improve the quality of life,which is worth promoting.
2022 Vol. 29 (11): 135-138 [Abstract] ( 41 ) HTML (1 KB)  PDF (547 KB)  ( 44 )
139 Application of flipped classroom combined with multiple disciplinary team in the teaching of hematology for professional degree postgraduates
ZHANG Wei1 QIU Wei2 YANG Lian3 WANG Wenping4 SHI Guoyou5 TANG Guiying2 SHI Jinning1▲
Flipped classroom(FC)takes students as the main body,changes the teaching process,promotes the internalization of students′ knowledge,and becomes a promising inquiry teaching mode.Multidisciplinary collaborative diagnosis and treatment(MDT)emphasizes comprehensive and individual diagnosis and treatment of diseases,and its application in medical teaching is helpful to train students′ systematic clinical thinking,which has become a direction of clinical teaching reform.In this paper,the characteristics and application prospects of FC and MDT models were analyzed,and the experience and thinking of the combined application of the two models in hematology teaching of professional graduate students in the Affiliated Jiangning Hospital with Nanjing Medical University were summarized,so as to provide some reference for improving the clinical competence of professional graduate students in the diagnosis and treatment of hematology diseases and improving the teaching level of teachers.
2022 Vol. 29 (11): 139-142 [Abstract] ( 41 ) HTML (1 KB)  PDF (652 KB)  ( 102 )
143 Analysis and discussion on current situation of nursing staff participating in continuing medical education in hospital
ZHAO Ying DU Ran XU Li WANG Lihua

Objective To explore the situation of nursing continuing education in hospital and provide theoretical basis for nursing management department to develop targeted training programs.Methods A total of 618 nursing staff from Beijing Aerospace General Hospital from November 2018 to October 2019 were selected as the research subjects.A self-designed questionnaire was used to investigate the current situation of nursing staff participating in continuing education.Results The nursing staff aged from 30 to ＜40 was the largest,accounting for 43.2%.Nursing staff working years in 11 to 20 years was the most,accounting for 46.61%.The number of nursing staff who have obtained professional title above primary level was the largest,accounting for 71.84%.The number of nursing staff with college degree or above was the largest,accounting for 98.22%.The number of hospital nursing staff who had participated in provincial and municipal continuing education programs was the largest,accounting for 84.63%.The number of nursing staff who hoped to obtain education through distance teaching was the largest,accounting for 91.59%.The number of people needing to increase nursing professional knowledge was the largest,accounting for 76.58 %.There was statistical significance in cognition of continuing education among nursing staff of different ages and educational backgrounds(P＜0.05).Conclusion Hospital nursing staff has a positive attitude towards continuing education and are aware of the importance of continuing education.The continuing education of nursing staff should be strengthened urgently,and effective training programs should be put forward according to the working conditions of nursing staff,and the importance of continuing education should be strengthened to improve the overall quality of nursing staff and the quality of nursing.
2022 Vol. 29 (11): 143-145 [Abstract] ( 57 ) HTML (1 KB)  PDF (526 KB)  ( 47 )
146 Application of real-time feedback device in cardiopulmonary resuscitation teaching
WANG Lyu1 MA Linhao1 JI Ruihua2▲
Objective To explore the application effect of real-time feedback device in cardiopulmonary resuscitation teaching.Methods A total of 40 senior clinical medicine undergraduates who were practicing in Changzheng Hospital Affiliated to Naval Military Medical University in December 2020 were selected as the research objects.According to the computer random number method,they were divided into control group and observation group,with 20 cases in each group.Conventional hands-free cardiopulmonary resuscitation was performed in the control group,and hands-free cardiopulmonary resuscitation was performed in the observation group with real-time feedback device.The compression frequency,compression depth,full thoracic rebound ratio and the overall compression pass rate of the two groups of students were compared.Results The compression depth of the observation group was deeper than that of the control group,the frequency of chest external compression was lower than that of the control group,and the proportion of thoracic rebound was higher than that of the control group,the differences were statistically significant(P＜0.05).The ratio of pressing depth ＞5 cm and pressing frequency 100-120 times/min in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).The overall press qualified rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Real-time feedback device can obviously improve the quality parameters of cardiopulmonary resuscitation,which is worth using in clinical teaching.
2022 Vol. 29 (11): 146-149 [Abstract] ( 41 ) HTML (1 KB)  PDF (538 KB)  ( 90 )
150 Effect observation and nursing of traditional Chinese medicine Detoxification Antiitching Solution on pruritus of uremic hemodialysis patients
ZOU Luting CHEN Huying HUANG Wenping
Objective To discuss the treatment effect of traditional Chinese medicine Detoxification Antiitching Solution on uremia hemodialysis patients.Methods A total of 44 patients with uremia hemodialysis and skin pruritus admitted to Jiujiang First People′s Hospital from January 2018 to December 2019 were selected as the research subjects,they were divided into control group and observation groups according to random number table method,with 22 cases in each group.The control group used Compound Dexamethasone Acetate Cream external coating treatment combined with targeted nursing,the observation group used traditional Chinese medicine Detoxification Antiitching Solution external coating or immersion treatment combined with targeted nursing.The treatment effect,symptoms scores before and after treatment and nursing satisfaction of the two groups were compared.Results The total effective rate of treatment of observation group was higher than that of control group,the difference was statistically significant(P＜0.05).The symptom score of observation group was lower than that of control group,the difference was statistically significant(P＜0.05).The total nursing satisfaction of observation group was higher than that of control group,the difference was statistically significant(P＜0.05).Conclusion The treatment effect of traditional Chinese medicine Detoxification Antiitching Solution on uremia hemodialysis patients is remarkable,which can effectively relieve the itching degree of patients.Traditional Chinese medicine Detoxification Antiitching Solution combined with targeted nursing can effectively improve their nursing satisfaction and promote the harmony between doctors,nurses and patients.
2022 Vol. 29 (11): 150-152 [Abstract] ( 45 ) HTML (1 KB)  PDF (756 KB)  ( 118 )
153 Effect of targeted nursing methods on the quality of life and blood glucose indexes of patients with diabetes mellitus complicated with malignant tumor of digestive tract
FAN Feng
Objective To investigate the impact of targeted nursing methods on the quality of life of patients with diabetes mellitus complicated with malignant tumor of digestive tract.Methods A total of 62 patients with diabetes mellitus complicated with malignant tumor of digestive tract admitted to the 334 Hospital Affiliated to Nanchang University from January 2019 to December 2020 were selected as the research objects,they were divided into control group and observation group according to random number table method,with 31 cases in each group.The control group adopted conventional nursing methods,and the observation group adopted targeted nursing methods based on the nursing method of the control group.The quality of life and blood glucose indexes of the two groups were compared.Results After 3 months of nursing,the quality of life scores of the observation group were higher than those of the control group,the differences were statistically significant(P＜0.05).After 3 months of nursing,the blood glucose index of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Targeted nursing methods have a positive impact on the quality of life and blood glucose index of patients with diabetes mellitus complicated with gastrointestinal cancer,and it is worthy of application in clinical practice.
2022 Vol. 29 (11): 153-156 [Abstract] ( 41 ) HTML (1 KB)  PDF (698 KB)  ( 47 )
157 Application effect of innovative nursing intervention in transurethral plasmakinetic resection of prostate
LI Xueqing LI Lianying ZUO Yutao LIU Yanmei YU Yunyan LIU Jinxiu
Objective To explore the effect of innovative nursing intervention in transurethral plasmakinetic resection of prostate.Methods A total of 100 patients who underwent transurethral plasmakinetic resection in the Operating Room of Red Cross Hospital of Wuzhou City,Guangxi Zhuang Autonomous Region from September 2017 to March 2020 were selected as the research objects.They were divided into observation group(50 cases)and control group(50 cases)by random number table method.The patients in the control group received routine nursing and the patients in the observation group received innovative nursing intervention.The total contamination rate of intraoperative flushing fluid overflow or spatter,the retention rate of intraoperative specimens,the comfort rate of patients and the incidence of shivering were compared between the two groups.Results The total contamination rate of intraoperative flushing fluid overflow or spatter in the observation group(8.00%)was lower than that in the control group(28.00%),the specimen retention rate([99±1]%)was higher than that in the control group([95±3]%),the difference was statistically significant(P＜0.05).The comfort rate of patients in the observation group(94.00%)was higher than that in the control group(78.00%),the difference was statistically significant(P＜0.05).The incidence of shivering in the observation group(0%)was lower than that in the control group(10.00%),and the difference was statistically significant(P＜0.05).Conclusion The application of innovative nursing intervention in patients undergoing transurethral plasmakinetic resection of the prostate can effectively reduce the pollution caused by the splashing of intraoperative flushing liquid or spatter,improve the retention rate of intraoperative specimens and the comfort rate of patients,and reduce the incidence of shivering.
2022 Vol. 29 (11): 157-159 [Abstract] ( 39 ) HTML (1 KB)  PDF (756 KB)  ( 44 )
160 Application effect of emotional care intervention based on social psychological factors in patients with malignant bone tumor
DUAN Liuhua SHEN Yuanyuan▲ LUO Kun
Objective To explore the application effect of emotional care intervention based on social psychological factors in patients with malignant bone tumor.Methods A total of 60 patients with malignant bone tumor admitted to Jiangxi Cancer Hospital from October 2019 to June 2021 were selected as the research objects.They were divided into experimental group and control group by random number table method,with 30 patients in each group.Patients in the control group were treated with routine nursing,and patients in the experimental group were treated with emotional care intervention nursing based on social psychological factors.Quality of life questionnaire core scale(QLQ-C30),short form 36 health survey(SF-36)and visual analogue scale(VAS)scores were compared between the two groups.Results Before nursing,there was no statistically significant difference in QLQ-C30 score between the two groups(P＞0.05).After nursing,QLQ-C30 score of experimental group was higher than that of control group,the difference was statistically significant(P＜0.05).Before nursing,there was no statistically significant difference in SF-36 score between the two groups(P＞0.05).After nursing,the SF-36 score of the experimental group was higher than that of the control group,the difference was statistically significant(P＜0.05).Before nursing,there was no statistically significance in VAS score between the two groups(P＞0.05).After nursing,VAS score of experimental group was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion For patients with malignant bone tumor,emotional care intervention based on social psychological factors can improve patient compliance,relieve patients′ pain,and improve patients′ quality of life.
2022 Vol. 29 (11): 160-164 [Abstract] ( 46 ) HTML (1 KB)  PDF (711 KB)  ( 52 )
165 Application effect of self-efficacy nursing in patients with gestational diabetes based on the theory of nurse-patient interaction reaching standard
ZHENG Ting
Objective To explore the application effect of self-efficacy nursing in patients with gestational diabetes mellitus(GDM)based on the theory of nurse-patient interaction reaching the standard.Methods A total of 80 patients with GDM who received treatment in Shangrao Maternal and Child Health Hospital from January 2017 to December 2020 were selected as the research objects,and were divided into observation group and control group by random number table method,with 40 cases in each group.The control group adopted routine intervention methods such as health education and psychological nursing,and the observation group adopted self-efficacy nursing under the theory of nurse-patient interaction standard on the basis of the control group.The serum glucose level(fasting plasma glucose[FPG],2 h postprandial blood glucose[2 h PG],glycosylated hemoglobin[HbAlc]),self-management ability score(selfefficacy for diabetes[SED],summary of diabetes self-care activities[SDSCA])and psychological status(symptom checklist-90[SCL-90])score of patients in the two groups were compared before intervention and 2 months after intervention.Results Before intervention,there was no significant difference in FPG,2 h PG and HbAlc levels between two groups(P＞0.05).After intervention,the levels of FPG,2 h PG and HbAlc in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Before intervention,there was no significant difference in SDSCA and SED scores between two groups(P＞0.05).After intervention,SDSCA score of observation group was lower than control group,SED score was higher than control group,the differences were statistically significant(P＜0.05).Before intervention,there was no significant difference in psychological status between the two groups(P＞0.05).After intervention,the scores of anxiety,fear and depression in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Self-efficacy nursing under the theory of nurse-patient interaction compliance is beneficial to helping control blood glucose,improving selfmanagement ability and regulating negative emotions of patients with GDM,thus it is worthy of clinical promotion.
2022 Vol. 29 (11): 165-168 [Abstract] ( 44 ) HTML (1 KB)  PDF (744 KB)  ( 133 )
169 Analysis of the effect of rapid rehabilitation nursing in patients with lumbar disc herniation
QIU Tingting1 BAO Zhangli2 LIN Fangfang3 YE Qiuhui2▲
Objective To observe the effect of rapid rehabilitation nursing in patients with lumbar disc herniation.Methods A total of 84 patients with lumbar disc herniation in the Second Department of Orthopedics and Department of Emergency of Ningde Municipal Hospital of Ningde Normal University from October 2018 to December 2020 were selected as research subjects.They were divided into control group and observation group by random number table method,with 42 cases in each group.The control group was treated with routine nursing,and the observation group was treated with rapid rehabilitation nursing.The pain visual analogue scale(VAS),modified Barthel index(MBI)and Oswestry disability index(ODI)scores were compared between the two groups before and after intervention.Results Before intervention,there were no statistically significant differences in VAS,MBI and ODI scores between the two groups(P＞0.05).After two weeks of intervention,VAS and ODI scores of observation group were lower than those of the control group,and the differences were statistically significant(P＜0.01).After two weeks of intervention,MBI score of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.01).Conclusion Rapid rehabilitation nursing has a better effect on patients with lumbar disc herniation,whith is worthy of clinical promotion.
2022 Vol. 29 (11): 169-171 [Abstract] ( 38 ) HTML (1 KB)  PDF (713 KB)  ( 53 )
172 Application of cluster nursing measures in "three-catheter" nosocomial infection control in intensive care unit
HUANG Fang YI Xiaomei
Objective To explore the application effect of cluster nursing measures in the "three-catheter" nosocomial infection control in intensive care unit(ICU).Methods A total of 82 critically ill patients admitted to the ICU of the Second People′s Hospital of Yichun City from December 2019 to December 2020 were selected as the research subjects.They were divided into the observation group(41 cases)and the control group(41 cases)by random number table method.The control group were received routine ICU nursing,while the observation group received cluster nursing on the basis of the control group,and continued nursing until the patients were discharged.The scores of catheter infection prevention knowledge,belief and action scale,ICU stay time,hospital stay,hospitalization cost,incidence rate of catheter infection,and nursing satisfaction were compared between the two groups.Results After intervention,the nursing staff′s infection control ability score in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The incidence of catheter infection in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The ICU stay time and hospital stay in the observation group were shorter than those in the control group,and the hospitalization cost was lower than that in the control group,with statistical significances(P＜0.05).The total nursing satisfaction of observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Cluster nursing measures can improve the infection control ability of ICU nurses,help reduce the occurrence of catheter infection,shorten the ICU admission,hospital stay,reduce hospitalization costs,and improve nursing satisfaction.
2022 Vol. 29 (11): 172-175 [Abstract] ( 39 ) HTML (1 KB)  PDF (700 KB)  ( 17 )
176 Application effect of comfort nursing for patients with severe pancreatitis during gastrointestinal decompression
LI Jing ZHAO Xue NI Na QU Ying HU Xue▲
Objective To explore the effect of comfort nursing during gastrointestinal decompression in patients with severe pancreatitis.Methods A total of 80 patients with severe pancreatitis hospitalized in the Second Department of General Surgery of Hongqi Hospital Affiliated to Mudanjiang Medical College from January 2018 to January 2019 were selected as the research objects.They were divided into observation group and control group by the random number table method,with 40 cases in each group.The control group was assisted with gastrointestinal decompression nursing,and the observation group was assisted with gastrointestinal decompression nursing combined with comfort nursing.The profile of mood states(POMS)score,self perceived comfort score,incidence of adverse reactions in nursing and nursing satisfaction before and after intervention were compared between the two groups.Results There were no significant differences in the scores of tension and anxiety,energy and vitality,fatigue and dullness,panic and confusion,depression and discouragement between the two groups before intervention(P＞0.05).After intervention,the scores of tension and anxiety,energy and vitality,fatigue and dullness,panic and confusion,depression and discouragement in the two groups were lower than those before intervention,and the scores of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in the score of self perceived comfort between the two groups before intervention(P＞0.05).After intervention,the score of self perceived comfort in the two groups was higher than that before intervention,and the score of self perceived comfort in the observation group was higher than that in the control group,the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).The nursing job satisfaction of the observation group was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Comfort nursing can alleviate patients′ personal emotions,improve their physical and mental comfort,reduce the incidence of adverse reactions and improve patients′nursing satisfaction.The overall nursing effect is ideal.
2022 Vol. 29 (11): 176-179 [Abstract] ( 39 ) HTML (1 KB)  PDF (698 KB)  ( 226 )
180 Application of early postoperative intake of water and food in the second trimester of pregnant women with cervical cervical ligation
CHEN Chen CAO Bing CUI Xiaohua YUAN Yaping▲
Objective To investigate the effect of early postoperative intake of food and drink in the second trimester of pregnant women with cervical cervical ligation.Methods A total of 60 cases of pregnant women in their second trimester who underwent transvaginal cervical ligation under spinal anesthesia in Women′s Hospital of Nanjing Medical University from June 2019 to December 2020 were selected as the research objects.They were divided into control group and experimental group by random number table method,with 30 cases in each group.Patients in the control group were strictly abstained from food and drink for 6 h after surgery according to ward nursing routine,while those in the experimental group were allowed to drink and eat as appropriate without nausea,vomiting and other gastrointestinal discomfort and subjective eating intention.The recovery of intestinal peristalsis,postoperative complications,length of hospital stay and satisfaction were compared between the two groups.Results The first exhaust time and defecation time of the experimental group were shorter than those of the control group,and the differences were statistically significant(P＜0.05).The application rate of laxative in experimental group was lower than that in control group,and the difference was statistically significant(P＜0.05).The incidence of abdominal distension in experimental group was lower than that in control group,and the difference was statistically significant(P＜0.05).There were no significant differences in the incidence of postoperative nausea and vomiting,vaginal bleeding and abortion between the two groups(P＞0.05).The number of days of hospitalization in the experimental group was less than that in the control group,and the satisfaction was higher than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Under the evaluation and guidance of professional nursing staff,the early drinking and eating of patients after vaginal cervical cerclage under intraspinal anesthesia is safe and feasible,and it can help patients recover and improve satisfaction after surgery.
2022 Vol. 29 (11): 180-183 [Abstract] ( 36 ) HTML (1 KB)  PDF (740 KB)  ( 10 )
184 Application effect of breathing training and psychological counseling in patients with liver MR enhanced scanning
GONG Xinghong ZHENG Yajun▲
Objective To explore the effect of breathing training and psychological counseling in patients with liver MR-enhanced scanning.Methods A total of 130 patients undergoing enhanced liver MR scans who were admitted to Xianning First People′s Hospital from April 2019 to March 2021 were selected as the research subjects,and they were divided into the observation group(n=65)and the control group(n=65).Patients in the control group were received routine nursing care,and patients in the observation group were received respiratory training and psychological counseling on the basis of routine nursing.The psychological status and the incidence of adverse reactions of the two groups of patients were compared.Results There were no significant differences in the scores of self-rating anxiety scale(SAS)and self-rating depression scale(SDS)between the two groups before intervention(P＞0.05).The scores of SAS and SDS in the two groups after intervention were lower than those before intervention,and scores of SAS and SDS in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The application of breathing training and psychological counseling on the basis of routine nursing in patients with enhanced liver MR scan can improve the mental state and reduce the incidence of adverse reactions.
2022 Vol. 29 (11): 184-186 [Abstract] ( 40 ) HTML (1 KB)  PDF (741 KB)  ( 28 )
187 Application effect of evidence-based nursing in the patients with kidney stones
GAO Fei
Objective To explore the application effect of evidence-based nursing in the patients with kidney stones.Methods A total of 94 patients with renal stones who underwent minimally invasive percutaneous nephrolithotripsis in Shenyang Red Cross Hospital from June 2020 to June 2021 were selected as research objects.According to the random number table method,they were divided into the reference group(n=47)and the study group(n=47).Patients in the reference group were given routine nursing,and patients in the research group were given evidence-based nursing.The classification of pain and the total incidence of complications before and after nursing were compared between the two groups.Results There was no statistical significance in the pain grading before nursing between the two groups(P＞0.05).The pain grading of the two groups after nursing was better than before nursing,and the pain grading of the research group was better than that of the reference group,the difference was statistically significant(P＜0.05).The total incidence of complications in the study group was 4.26%,lower than 21.29% in the reference group,and the difference was statistically significant(P＜0.05).Conclusion The application of evidence-based nursing in the nursing of patients with kidney stones has a significant effect,which can effectively relieve postoperative pain and reduce complications,and has the value of promotion and application.
2022 Vol. 29 (11): 187-189 [Abstract] ( 42 ) HTML (1 KB)  PDF (689 KB)  ( 130 )
190 Influence of personalized cognitive behavioral nursing intervention on neurological function and ability of daily living in patients with cerebral infarction during rehabilitation
SHI Caiping1 HAN Xu2
Objective To explore the impact of personalized cognitive behavioral nursing intervention on patients with cerebral infarction in the rehabilitation period.Methods A total of 76 patients with cerebral infarction during the rehabilitation period who were admitted to the Department of Internal Medicine,Jurong City Hospital of Traditional Chinese Medicine,Zhenjiang City,Jiangsu Province from August 2019 to May 2020 were selected as the subjects of this study,and they were divided into study group and control group according to random number table method,with 38 patients in each group.The control group took routine care,and the study group added personalized cognitive behavioral care on the basis of the control group.The neurological function and daily living ability of the two groups before and one month of nursing were compared,the compliance of the two groups of patients during one month of nursing was compared.Results The National Institutes of Health stroke scale(NIHSS)score of the two groups after nursing care for 1 month was lower than those before nursing,and the NIHSS score of the study group for 1 month of nursing care was lower than that of the control group,and the differences were statistically significant(P＜0.05).The Barthel index(BI)of the two groups of nursing care for one month was higher than that before nursing,and the BI index of the study group for one month of nursing care was higher than that of the control group,the differences were statistically significant(P＜0.05).The compliance of the study group during one month of nursing was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion The implementation of personalized cognitive behavioral nursing interventions for patients with cerebral infarction during the rehabilitation period can improve the patients′neurological function and ability of daily living,and improve patient compliance.
2022 Vol. 29 (11): 190-192 [Abstract] ( 36 ) HTML (1 KB)  PDF (755 KB)  ( 121 )
193 Application effect of all-round nursing intervention in patients with arrhythmia of coronary heart disease
SUN Jing WANG Shizhan WANG Yu
Objective To study the effect of all-round nursing intervention in patients with arrhythmia of coronary heart disease.Methods From December 2019 to December 2020,250 patients with arrhythmia of coronary heart disease in the Department of Cardiovascular Medicine of Liaoning Provincial People′s Hospital were selected as the research objects.They were divided into the reference group(125 cases)and the experimental group(125 cases)by the balltouching method.The reference group received conventional nursing,and the experimental group received all-round nursing.Quality of life,mood before and after nursing and heart rate were compared between the two groups.Results There were no significant differences in quality of life and self-rating anxiety scale(SAS)scores between the two groups before nursing(P＞0.05).After nursing,quality of life score of experimental group was higher than that of reference group,SAS score of experimental group was lower than that of reference group,the differences were statistically significant(P＜0.05).The quality of life scores of the two groups after nursing were higher than those before nursing,the differences were statistically significant(P＜0.05).The SAS scores of the two groups after nursing were lower than those before nursing,the differences were statistically significant(P＜0.05).The heart rate of experimental group was higher than that of reference group,and the difference was statistically significant(P＜0.05).Conclusion Comprehensive nursing intervention can help patients with arrhythmia of coronary heart disease improve the quality of life,alleviate the adverse mood,reduce the impact of the disease on their own,worthy of promotion and application.
2022 Vol. 29 (11): 193-196 [Abstract] ( 33 ) HTML (1 KB)  PDF (739 KB)  ( 93 )
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