不同血液净化方式对慢性肾功能衰竭尿毒症患者肾功能指标的影响比较

Abstract
Figure/Table
References (21)
Related Citation (15)

Download: PDF (619 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore and analyze the effect of three different blood purification modes on the renal function indexes and nutritional status of patients with chronic renal failure and uremia,and to observe the adverse reactions during the application of different blood purification methods.Methods A total of 120 patients with chronic renal failure and uremia admitted to Liaoyang Central Hospital in Liaoning Province from April 2018 to April 2021 were selected as the research objects.The random number table method was used to divide them into group A with 40 cases,group B with 40 cases,and group C with 40 cases.Group A was given conventional hemodialysis treatment,group B was given high-flux hemodialysis treatment,group C was given hemodiafiltration treatment.The renal function indexes and nutrition-related indexes of patients of the three groups were compared,and the adverse reactions during the treatment period were observed.Results The levels of erythrocyte sedimentation rate(ESR),urine protein,and serum creatinine(SCr)after treatment in the three groups were lower than those before treatment,the blood urea nitrogen(BUN)levels in the three groups were higher than those before treatment,the levels of ESR,urine protein,and SCr in group B were lower than those of groups A and C,and the BUN level in group B was higher than that of groups A and C,the levels of ESR,urine protein,SCr and BUN in group A were higher than those in group C,with statistically significant differences(P＜0.05).The levels of total protein(TP),albumin(ALB),prealbumin(PA),and hemoglobin(Hb)after treatment in the three groups were higher than those before treatment,the levels of TP,ALB,PA and Hb in group B were higher than those in groups A and C,with statistically significant differences(P＜0.05).There was no statistical significance in the total incidence of adverse reactions among the three groups(P＞0.05).Conclusion The effect of high-flux hemodialysis in the treatment of chronic renal failure and uremia is significantly better than that of conventional hemodialysis and hemodiafiltration treatment.It not only effectively facilitates patients′ renal function indicators,but also helps to improve the patients′ nutritional status without increasing adverse reactions during the treatment period in high safety.

Key words： Hemodialysis purification High-flux hemodialysis Hemodiafiltration Chronic renal failure Uremia Renal function Nutrition Safety

Received: 18 August 2021

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	YANG Bo

Cite this article:

YANG Bo. Effect comparison of different blood purification methods on renal function indexes in patients with chronic renal failure and uremia[J]. 中国当代医药, 2022, 29(11): 24-28.

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I11/24

[1]	吴其顺，王文燕，何建强，等.高通量血液透析联合血液透析滤过序贯治疗慢性肾功能衰竭临床观察[J].山东医药，2017，57（37）：87-89.
[2]	任志龙，张璐，刘杰，等.高通量血液透析对慢性肾功能衰竭尿毒症患者肺总量、免疫球蛋白水平及生活质量的影响[J].医学临床研究，2017，34（1）：8-11.
[3]	黄莉，王永剑.不同血液净化方式对脓毒症所致急性肾损伤的临床疗效观察[J].中国医刊，2019，45（7）：798-800.
[4]	蒋利.组合血液净化方式对尿毒症性脑病患者凝血功能、血流动力学指标的影响[J].血栓与止血学，2020，26（3）：432-433.
[5]	李琦晖，苟晓燕，邓舜天，等.不同透析模式对尿毒症患者Hcy、FGF-23 及血管的影响[J].重庆医学，2020，49（4）：522-525，530.
[6]	邓湘佐，高利丽，宋晓平，等.血液净化联合重组EPO 治疗对尿毒症患者骨代谢的影响[J].西南国防医药，2019，29（3）：326-328.
[7]	凌萌，张琳琳.不同抗凝方法对血液净化患者凝血功能的影响[J].热带医学杂志，2019，19（9）：1154-1156.
[8]	李育娟.高通量血液透析治疗急危重肾功能衰竭患者的疗效[J].医学临床研究，2018，35（4）：801-803.
[9]	王王萌，蒋红利，何荃，等.血液透析联合血液灌流治疗对慢性肾功能衰竭患者肾功能、微炎症状态和血液净化效果的影响[J].现代生物医学进展，2018，18（8）：1413-1511，1514.
[10]	林欣然，梁海琴，蔡美华.不同血液净化方法治疗尿毒症脑病临床疗效及对患者神经功能的影响[J].现代中西医结合杂志，2019，28（4）：403-406.
[11]	吴智慧，樊后宽.固肾排毒液+结肠透析对慢性肾功能衰竭患者肾功能及细胞炎症因子的影响[J].现代中西医结合杂志，2018，27（2）：198-201.
[12]	李团结，李旭，于泽莺，等.单次不同血液净化方式清除不同分子量尿毒症毒素的疗效研究[J].中国血液净化，2020，19（4）：246-247.
[13]	温莉玲，梁春波.高通量血液透析对慢性肾功能衰竭尿毒症患者血清因子及近期预后影响[J].临床军医杂志，2019，47（4）：354-356，359.
[14]	阮春芸，刘圣山.高通量血液透析联合血液灌流在尿毒症治疗中的应用研究[J].中国当代医药，2021，28（19）：130-133.
[15]	刘春玲，李明风，陈亮.高通量透析和普通血液透析治疗慢性肾衰竭尿毒症的优劣差异[J].中国医药科学，2020，10（7）：231-234.
[16]	关兴晔.高通量透析结合血液灌流对老年慢性肾衰竭维持性血液透析患者炎症因子与生活质量的影响[J].中国当代医药，2021，28（3）：115-118.
[17]	库兰·阿布里哈衣尔.高通量血液透析联合肾康注射液对慢性肾功能不全临床疗效和微炎症状态的影响[J].中国医药科学，2021，11（17）：106-109.
[18]	关毅标，黄胜，李丽波，等.尿毒症患者应用高通量血液透析与常规血液透析两种治疗方案的效果[J].中国医药科学，2021，11（15）：193-196.
[19]	孙柯，王光腾，梅长林.腹膜透析治疗36 例急性肾损伤患者的疗效分析[J].中国血液净化，2019，18（4）：223-225.
[20]	任永强，魏雅娟，曹亚南，等.不同血液净化方式对维持性血透患者微炎性状态的影响[J].武警医学，2019，30（7）：603-606.
[21]	李婷婷.高通量血液透析治疗尿毒症的临床效果[J].中国当代医药，2020，27（1）：91-93，98.