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Quick Search     Adv Search 2016 Vol. 23, No. 22 Published: 2016-08-08   4 Analysis of radiosensitivity of paclitaxel on human gastric cancer cell PENG Qiang;WU Chuan-gao;DONG Zhu-qing Objective To observe the effect of paclitaxel（PA）on the radiosensitivity of human gastric cancer cell line SGC7901.Methods MTT assay was employed to obtain the 50%inhibition concentration（IC50）of PA on SGC7901 cells. 20%of the IC50dose was treated as sensitizing concentration.The clonogenic assay was used to analyze the cell viability of radiation group and PA（sensitizer concentration）plus radiation group with X-ray of 0，2，4，6 and 8 Gy.The changes of cell cycle and cell morphology changes were observed.Results The IC50of PA on SGC7901 cells was 16.11 μg/ml. The cell viability got decreased with increasing radiation dose in radiation group and PA plus radiation group.The cell viabilities of PA plus radiation groupwere lower than those of radiation group at the dose of 4，6 and 8 Gy.There was higher percentage in the G2/M phase，and lower percentage in the S phase in PA plus radiation group versus the other two groups（P＜0.05）.Conclusion PA can enhance the radiosensitivity of SGC7901 cells.The mechanism is connected with that it can induce cell apoptosis and G2/M phase retardation. 2016 Vol. 23 (22): 4-6 [Abstract] ( 162 ) HTML (43 KB)  PDF  (0 KB)  ( 27 ) 7 Primary observation on PLGA/TCP scaffolds incorporating icariin in repairing the defect of knee cartilage accordance with the biological characteristics of the rabbits LI Wei;WANG Zhan-wei;WU Xiao;YU Fei;ZHANG Wen-tao;JIANG Chang-qing Objective To explore the characteristics of the PLGA/TCP scaffolds incorporating icariin in repairing the defect of knee cartilage of the rabbits.Methods The model of cartilage defect was created on the patellar groove.They were drilled by micro-fracture and divided into blank group，control group and experimental group，which received no scaffold，PLGA/TCP scaffolds and the the PLGA/TCP scaffolds incorporating icariin.They were sacrificed after 6 months. CT was used to explored the bone scaffold/three-dimensional structure and the gross observation was used to evaluated the articular cartilage.Results The CT scan showed they had whole and complete structure of knee in the experimental group and worse structure in the control group，the blank group had lose the whole structure.The gross observation showed the experimental group kept fresh color，and grey in the control group，the defect was kept in the blank group. The experimental group was better than that in control group and blank group（P＜0.05），and control group was better than blank group（P＜0.05）.Conclusion The PLGA/TCP scaffolds incorporating icariin can keep good structure in repairing the defect of knee cartilage.The gross observation of the articular cartilage in the experimental group is best.It provides primary basis for exporing the repair effect father. 2016 Vol. 23 (22): 7-10 [Abstract] ( 178 ) HTML (42 KB)  PDF  (0 KB)  ( 31 ) 11 Maxillary sinus floor elevation overview and recent development ZHAO Li-juan;HE Dong-ning Because of the structure specialty，loss of maxillary posterior teeth normally leads to sever vertical bone mass loss at local area of maxillary molar.It limits indications of the dental implant treatment and increases risks of dental implant surgery.To date，loss of maxillary posterior teeth is still the biggest barrier to the dental implant surgery.Maxillary sinus floor elevation is the most effective and reliable method to solve the insufficient bone mass at local area of maxillary molar.It is very important to understand and master this major method.This paper is an overview of the research progress of maxillary sinus floor elevation，based on recent international literatures.The basic maxillary sinus floor structure and elevation method are presented.Different elevation methods are compared.This paper also reviews the implant material options and its complications. 2016 Vol. 23 (22): 11-13转17 [Abstract] ( 155 ) HTML (42 KB)  PDF  (0 KB)  ( 12 ) 14 Research progress in the relationship between obstructive sleep apnea hypopnea syndrome and aortic dissection HE Chang-shun;SUN Zhan-guo;ZHANG Xue-min;ZHANG Xiao-ming;HAN Fang;ZHANG Tao;JIANG Jing-jun Obstructive sleep apnea hypopnea syndrome（OSAHS）is the disease that refers to the throat by a complete or incomplete closure during sleep，causing apnea and hypopnea recurrent body caused a series of pathophysiological responses clinical syndrome.OSAHS has connected with hypertension，coronary heart disease，heart failure，arrhythmias and damage of endothelial function and other cardiovascular diseases.A correct understanding of the relationship between OSAHS and cardiovascular disease can help early diagnosis and treatment of diseases，giving great help for patients at improving the quality of life.This paper reviewed that analyze the current and relevant to the pathophysiology of OSAHS relationship with aortic dissection. 2016 Vol. 23 (22): 14-17 [Abstract] ( 212 ) HTML (47 KB)  PDF  (0 KB)  ( 30 ) 18 Application effect of temporary cardiac pacemaker implantation with floating electrode catheter in femoral vein in slow arrhythmia with high degree atrioventricular block patient YE Zhi-gao;ZOU Rong;PAN Hui-juan;LIU Jin-chang;ZHAO Yan-chi 2016 Vol. 23 (22): 18-20转24 [Abstract] ( 161 ) HTML (42 KB)  PDF  (0 KB)  ( 21 ) 21 Cause and preventive measure of axial symptoms caused after cervical posterior single open-door laminoplasty ZHOU Zhi-gang;FU Jiang-ming;LI Qiang;YAN Zhao-hua;ZHOU Huan-bin;YU WeiHE;Jia-cheng Objective To explore the cause and preventive measure of axial symptoms caused after cervical posterior single open-door laminoplasty.Methods 38 cases of cervical spondylopathy treated with cervical posterior single opendoor laminoplasty and achieved complete follow-up from October 2009 to October 2013 in our hospital were selected and divided into group A and group B.Group A was early given isometric relaxation and contraction motion，muscle strength exercise of neck，shoulder，back muscles after operation，the neck was brake for 4 to 8 weeks by neck collar，the neck joint activity degree exercise，breast enlargement exercise was carried out step by step after 4 to 8 weeks.Group B was given postoperative cervical collar neck brake for 12 weeks，muscle strength and neck joint activity degree exercise was carried out step by step after 12 weeks.The patients were followed up by outpatient review，axial symptoms was evaluated according to the patient′s neck pain，stiffness，limited degree of activity，postoperative MRI image display.Axial symptoms was graded according to the severity of the symptoms，the impact of the quality of life，whether the use of pain medication.Results After operation，gradeⅠof the axial symptoms in group A was 28 cases（90.3%）and gradeⅡwas 3 cases（9.7%）.The axial symptoms in group B was 1 case（14.3%）of gradeⅡ，5 cases（71.4%）of gradeⅢand 1 case （14.3%）of gradeⅣ.Conclusion Isometric relaxation and contraction motion，muscle strength exercise of neck，shoulder，back muscles are early carried out after cervical posterior single open-door laminoplasty　（postoperative 3-5 days），the neck is brake for 4 to 8 weeks by neck collar，the neck joint activity degree exercise，breast enlargement exercise are carried out step by step after 4 to 8 weeks，which can effectively reduce the incidence of axial symptoms. 2016 Vol. 23 (22): 21-24 [Abstract] ( 166 ) HTML (40 KB)  PDF  (0 KB)  ( 21 ) 25 Research of the early diagnosis in nodular goiter combined with thyroid micro-carcinoma MENG Qing-bo Objective To explore the early diagnosis method of nodular goiter with thyroid micro-carcinoma.Methods 200 cases patients with nodular goiter from January 2011 to December 2014 in our hospital were selected as the research object，all patients underwent preoperative thyroid ultrasonography，were performed surgical treatment，and intraoperative frozen section examination was given.30 nodular goiter patients with postoperative pathological diagnosis of thyroid micro-carcinoma were selected as the observation group，the rest of 170 nodular goiter patients without thyroid micro-carcinoma were selected as the control group.The positive detection rate of thyroid micro-carcinoma was detected by color Doppler ultrasonography and intraoperative frozen section，and the nodule calcification status and the number of nodules was compared between the two groups respectively.Results The positive detection rate of preoperative color ultrasound was 26.67%，the positive detection rate of intraoperative frozen section was 56.67%，compared with the postoperative pathological diagnosis results，the difference was statistically significant（P＜0.05）.The nodule calcification rate and the proportion of individual nodules in the observation group was higher than that in the control group，with significant difference（P＜0.05）.Conclusion In clinical practice，the early diagnosis of nodular goiter with thyroid micro-carcinoma should be strengthened，which can be performed quickly and pathological examination in the process of nodular goiter，so as to determine the scope of surgical resection. 2016 Vol. 23 (22): 25-27 [Abstract] ( 152 ) HTML (40 KB)  PDF  (0 KB)  ( 39 ) 28 Clinical effect of lansoprazole combined with mosapride in the treatment of elderly patients with gastroesophageal reflux disease YI Xian-zu Objective To explore the effect of lansoprazole combined with mosapride in the treatment of elderly patients with gastroesophageal reflux disease.Methods 120 cases of elderly patients with gastroesophageal reflux disease in our department from March 2014 to March 2016 were selected and randomly divided into the control group and the treatmeng group，60 cases in each group.The control group was given lansoprazole enteric-coated capsules oral medication，the treatment group was treated with mosapridecitrate dispersible tablets on the basis of the treatment in the control group.The two groups were accepted for a periodof 8 weeks of treatment.The clinical effect of the two groups was compared，and the remission time of clinical symptoms and the signs，the incidence rate of complications in the two groups was recorded respectively.Results The total effective rate in the treatment group was 93.33%，which was higher than 71.67%in the control group，with significant difference　（P＜0.01）.The remission time of clinical symptoms and signs in the treatment group after treatment was shorter than that in the control group，with significant difference　（P＜0.01）.The incidence rate of complications in the treatment group was 3.33%，which was lower than 23.33%in the control group，with significant difference　（P＜0.05）.Conclusion The clinical effect of lansoprazole combined with mosapride in the treatment of elderly patients with gastroesophageal reflux disease is significant，and the complication is less，it is worthy of clinical promotion and application. 2016 Vol. 23 (22): 28-30 [Abstract] ( 190 ) HTML (38 KB)  PDF  (0 KB)  ( 31 ) 31 Clinical effect analysis of enteral immune micro-ecological nutrition in the treatment of severe acute pancreatitis YOU Wei-xing;JIANG Qian-hua;ZHANG Jie-xiong Objective To explore the clinical effect of enteral immune micro-ecological nutrition in the treatment of severe acute pancreatitis.Methods 120 cases of severe acute pancreatitis in our hospital from January 2014 to June 2015 were selected and divided into the control group and the observation group according to the different treatment methods，60 cases in each group.The observation group was treated with enteral immune micro-ecological nutrition，the control group was given only the conventional treatment，the clinical effects in the two groups was compared.Results The level of humoral immunity such as IgG，IgA，IgM and the cellular immunity such as CD3+，CD4+，CD8+，CD4+/CD8+in the observation group after treatment was higher than that in the control group after treatment，with significant difference （P＜0.05）.The level of the WBC count，serum pancreatic lipase （LIP），albumin　（ALB），C-reactive protein（CRP），amylase （AMS）in the observation group after treatment was better than that in the control group after treatment，with significant difference　（P＜0.05）.The APACHEⅡscore，Binder score and the mortality in the observation group after treatment was lower than that in the control group after treatment，the hospitalization time in the observation group after treatment was shorter than that in the control group after treatment，with significant difference　（P＜0.05）.Conclusion Enteral immune micro-ecological nutrition supports can improve the immune function，relief the disease and reduce the mortality in severe acute pancreatitis patients. 2016 Vol. 23 (22): 31-33 [Abstract] ( 149 ) HTML (38 KB)  PDF  (0 KB)  ( 41 ) 34 Application of mechanical ventilation in the treatment of critical heart failure WANG Zhi-min;ZHANG Biao;LI Zuo-qing Objective To explore clinical application significance of mechanical ventilation on treating critical heart failure.Methods From August 2012 to August 2015，32 patients with acute severe left heart failure treated in our hospital were selected into the study，all patients were performed with mechanical ventilation and the therapeutic effect was analyzed.Results After treatment，different symptoms were all greatly improved，including PaO2，PaCO2，SaO2，RR，HR and MBP，these indexes were displayed statistical differences before and after treatment（P＜0.01）.Conclusion For patients with acute severe left heart failure，application of mechanical ventilation can obtain a remarkable effect，effectively reduce the incidences of hyoxemia and hypercapnia，which is a rescuing scheme and worthy of clinical promotion. 2016 Vol. 23 (22): 34-36 [Abstract] ( 139 ) HTML (37 KB)  PDF  (0 KB)  ( 29 ) 37 Effect comparison of dynamic electrocardiogram and routine electrocardiogram in diagnosis of asymptomatic myocardial ischemia in patients with coronary heart disease DAI Shao-hua;CHEN Hao-gang;LIANG Cui-juan;CHEN Yi-ying;CHEN Hui-yan Objective To compare effect of dynamic electrocardiogram and routine electrocardiogram in diagnosis of asymptomatic myocardial ischemia in patients with coronary heart disease　（CHD）.Methods 150 patients with CHD in our hospital from January 2013 to December 2015 were selected as study subjects，the clinical data were analyzed retrospectively.All patients underwent routine ECG examination and dynamic electrocardiogram examination，and the results were observed.According to coronary angiography results as"gold standard"diagnosis of asymptomatic myocardial ischemia，diagnostic sensitivity，specificity and accuracy of ECG，Holter monitoring electrocardiogram in symptomatic myocardial ischemia were calculated and compared，and the diagnosis of the Kappa consistency between routine ECG，dynamic electrocardiogram and coronary angiography were calculated.Results In 150 patients with CHD，98 patients with asymptomatic myocardial ischemia were detected by coronary angiography.The diagnostic sensitivity，specificity and accuracy of routine electrocardiogram in asymptomatic myocardial ischemia was 72.45%，57.69%，67.33%，with 85.71%，76.92%，82.67%of dynamic electrocardiogram respectively，the differences was statistically significant（P＜0.05）.Kappa in the comparison of routine ECG and coronary angiography diagnosis was 0.526，there was medium consistency；Kappa in the comparison of dynamic electrocardiogram and coronary angiography was 0.719，there was good consistency.Conclusion The application of dynamic electrocardiogram in asymptomatic myocardial ischemia has higher diagnostic accuracy than the conventional electrocardiogram，and significant value in diagnosis，which can be used as the preferred method for diagnosis of asymptomatic myocardial ischemia. 2016 Vol. 23 (22): 37-39 [Abstract] ( 173 ) HTML (39 KB)  PDF  (0 KB)  ( 33 ) 40 Clinical effect analysis of enalapril folic acid in treatment of H type hypertension MA Guo-bin;ZHENG Bo-ren;YU Bi-jing Objective To study the clinical effect of enalapril folic acid in treatment of H type hypertension.Methods 200 patients with H type hypertension in our hospital from February 2013 to November 2015 were selected and divided randomly into routine group（n=100）and compound group（n=100）by sealed envelope non transparent method，patients in the routine group received enalapril treatment，while patients in the compound group received enalapril combined with enalapril folic acid treatment.Total effective rate of H type hypertension，incidence of cardiovascular and cerebrovascular events，difference of homocysteine　（Hcy）levels，systolic blood pressure and diastolic blood pressure before and after intervention，difference of quality of life after intervention were compared.Results Total efficiency in the compound group was higher than that in the routine group，the difference was statistically significant（P＜0.01）；Occurrence rate of cardiovascular and cerebrovascular events in the compound group was lower than that in the routine group，the difference was statistically significant（P＜0.01）.Level of Hcy，systolic blood pressure，diastolic blood pressure was similar before intervention，the difference was not significant（P＞0.05）；Above indicators after intervention had significant difference with those before intervention in two groups　（P＜0.05）；After intervention，level of Hcy，systolic blood pressure，diastolic blood pressure in the compound group was improved more significantly than that in the routine group respectively，the difference was significant（P＜0.05）.Quality of life in the compound group was significantly better than that in the routine group after intervention，the difference was significant（P＜0.05）.Conclusion Enalapril folic acid in the treatment of H type hypertension can effectively improve the level of blood pressure and Hcy levels，alleviation of clinical symptoms and promote quality of life，which has exact effect and is worthy of promotion. 2016 Vol. 23 (22): 40-42 [Abstract] ( 139 ) HTML (43 KB)  PDF  (0 KB)  ( 18 ) 43 Study on the clinical grading standard of intracerebral hemorrhage GrowthWU Yuan-shui1LI Xu-ping2CHEN Yi-rong3 WU Yuan-shui;LI Xu-ping;CHEN Yi-rong Objective To study the related factors of intracerebral hemorrhage（ICH）Growth，then establish a convenient，feasible and effective ICH Growth clinical scoring standard.Methods The clinical data of 300 patients with ICH（induce group）admitted to our hospital from 2009 to 2012 were retrospectively analyzed，the multivariate Logistic regression and other statistical analysis were used to analysis，after the establishment of clinical evaluation standard，80 patients with ICH admitted to hospital from 2013 to 2015 were selected as validated group.Results In 380 patients with ICH，199 patients with hematoma enlargement，their mean diastolic blood pressure（DBP）was（109±7）mmHg，mean systolic blood pressure　（SBP）was（201±15）mmHg，while average DBP of patients without hematoma enlargement was （105±6）mmHg，mean SBP with　（183±13）mmHg；average SBP was statistically significant in two groups（P＜0.05），and average DBP was no significant difference in two groups（P＞0.05）.The results of multivariate Logistic regression analysis indicated that drinking history，time from onset to first CT check，anticoagulant therapy and shape of hematoma were positively correlated with ICH Growth.The expected cases and the actual cases of ICH Growth in validation group were no significant difference（χ2=2.8876，P=0.5768）.Conclusion By drinking history，time from onset to first CT check，anticoagulant therapy，shape of hematoma four risk factors clinical criteria can better predict occurrence of ICH Growth. 2016 Vol. 23 (22): 43-45 [Abstract] ( 166 ) HTML (39 KB)  PDF  (0 KB)  ( 36 ) 46 Comparison of clinical therapeutic effects of craniotomy operation and cone skull suction therapy in treatment of cerebral hemorrhage SUN Wei;XI Bin;LIU Jian-min Objective To investigate the clinical effect of craniotomy operation and cone skull suction therapy in treatment of cerebral hemorrhage.Methods Altogether 81 cases of patients who were diagnosed as cerebral hemorrhage and underwent parallel surgical treatment in our hospital from December 2013 to October 2015 were enrolled in the study and randomly divided into two groups，with 40 patients in control group and 41 cases in treatment group.Patients in the control group was treated with traditional small bone window craniotomy hematoma removal，while patients in the treatment group accepted skull puncture aspiration and bloody swollen clearance therapy.Post-operative 3 d CT（computerized tomography）was performed to observe hemorrhage absorption and the clinical curative effects in two groups were compared.Results Although GCS in two groups were increased post-operatively，a more remarkable improvement as well as the proportion of less cases of severe coma and death according to GCS after postoperative 24 hours was seen in treatment group，with a significant difference　（P＜0.05）.Additionally，shorter duration of surgery，length of hospitalization and post-operative extubation time in the treatment group also showed superiority over those in the control group，with a significant difference　（P＜0.05）.As for nerve functions，an increase of Barthel index of patients in two groups after 7-day and 14-day treatment was found，especially for patients in treatment group，with a significant difference（P＜0.05）；In addition，treatment group had higher excellent and good rate in Barthel score，with a significant difference　（P＜0.05）.The hematoma clearance rate in two groups showed no significant difference（P＞0.05）.Conclusion The craniotomy operation and cone skull suction therapy can obtain good curative effect in treatment of cerebral hemorrhage，among which the cone skull suction therapy is featured with less invasion and fast recovery and deserves wider popularization. 2016 Vol. 23 (22): 46-48转66 [Abstract] ( 148 ) HTML (45 KB)  PDF  (0 KB)  ( 29 ) 49 Analysis of plasma homocysteine and cystatin C level change in patients with acute cerebral infarction WANG Zhi-min;HAN Ni Objective To test content of plasma homocysteine and cystatin C in patients with acute cerebral infarction and explore changes both in patients with acute cerebral infarction.Methods From May 2014 to December 2015，60 patients with cerebral infarction hospitalized in department of neurology of Wafangdian central hospital were selected as research objects（cerebral infarction group），30 healthy people over 40 years old without a history of cerebrovascular disease were selected as control group in our hospital medical center.Plasma homocysteine and cystatin C levels were compared between cerebral infarction group and control group，plasma homocysteine and cystatin C were compared between various types in cerebral infarction group and control group，the correlation between plasma homocysteine and cystatin C in cerebral infarction group was analyzed.Results The difference of plasma homocysteine and cystatin C levels was statistically significant（P＜0.05）between cerebral infarction group and control group，plasma homocysteine and cystatin C levels between the various types in cerebral infarction group，the difference was not statistically significant （P＞0.05）；plasma homocysteine was positively correlated with cystatin C levels.Conclusion Plasma homocysteine and cystatin C is closely related with acute cerebral infarction attack. 2016 Vol. 23 (22): 49-51 [Abstract] ( 147 ) HTML (39 KB)  PDF  (0 KB)  ( 12 ) 52 Effect comparison analysis of ultra-low large craniotomy and conventional craniotomy decompression under temporalis in the treatment of extremely severe craniocerebral trauma accompanying with cerebral hernia LIU Jun;YAN Jin-ting Objective To explore the effect comparison of ultra-low large craniotomy and conventional craniotomy decompression under temporalis in the treatment of extremely severe craniocerebral trauma accompanying with cerebral hernia.Methods From January 2013 to January 2016，clinical data from 66 patients extremely severe craniocerebral trauma with cerebral hernia admitted into our department were analyzed and evenly divided into ultra-low large craniotomy group　（ultra-low large craniotomy decompression under temporalis，n=33）and conventional craniotomy（conventional craniotomy decompression under temporalis，n=33）according to different surgical methods.The intracranial pressure，quality of life score，Synek grading，CAN grading and Huayang grading in the two groups were observed.Results Before surgery，the intracranial pressure，quality of life score，Synek grading，CAN grading and Huayang grading in two groups was all not displayed statistical differences respectively　（t=0.17，0.37，1.59，1.15 and 1.15，P＞0.05）.In the ultra-low large craniotomy group，the postoperative intracranial pressure，Synek grading，CAN grading and Huayang grading was（18.6± 3.9）mmHg，（2.8±0.4）grades，（1.5±0.2）grades and（1.8±0.3）grades respectively，much lower than（23.5±4.0）mmHg，（3.3± 0.3）grades，（1.8±0.3）grades and　（2.2±0.4）grades in the conventional craniotomy group.The quality of life score in the former group was（88.8±11.0）scores，higher than（75.4±12.3）scores in the latter one.The comparisons mentioned above were all displayed statistical differences　（t=5.04，4.66，5.74，4.78 and 4.60，P＜0.05）.Conclusion Ultra-low large craniotomy decompression under temporalis can greatly improve clinical symptoms with good effect on treating extremely severe craniocerebral trauma accompanying with cerebral hernia，which is worthy of clinical promotion and application. 2016 Vol. 23 (22): 52-54 [Abstract] ( 151 ) HTML (39 KB)  PDF  (0 KB)  ( 36 ) 55 Clinical study of sertraline combined with tiapride hydrochloride tablets in the treatment of patients with obsessive-compulsive disorder ZHAO Meng;ZHOU Xiu-zhi;SUN Min 2016 Vol. 23 (22): 55-57 [Abstract] ( 163 ) HTML (38 KB)  PDF  (0 KB)  ( 20 ) 58 The effect of whole course treatment on the community function of patients with schizophrenia XU Qing;WEN Yao-hui;LU Hong-xin;ZHANG Run-rong Objective To study the effect of the whole course treatment on the return to the community function of patients with schizophrenia.Methods 100 patients with schizophrenia from January 2015 to June in our hospital were researched and divided into observation group and control group by random，each group with 50 cases，patients in the control group were given routine community management，and patients in the observation group were given the whole treatment.The change of brief psychiatric rating scale（BPRS）and social function defect scale（SDSS）scores before and after treatment were compared，recurrence rate，re hospitalization rate，employment rate were compared.Results After treatment，BPRS and SDSS scores in the observation group were lower than those in the control group［（21.13±2.76）vs　（31.08± 3.03），（7.08±1.31）vs（10.87±2.24）］，the difference was statistically significant（P＜0.01）；the recurrence rate and rehospitalization rate in the observation group were lower than those in the control group（10%vs 36%，4%vs 24%），the employment rate was higher than that in the control group（56%vs 12%），the differences both were statistically significant（P＜0.01）.Conclusion Implementation of the whole course treatment in patients with schizophrenia，in helping patients to return to the community has a positive significance，it is worthy of promotion and application. 2016 Vol. 23 (22): 58-60 [Abstract] ( 151 ) HTML (39 KB)  PDF  (0 KB)  ( 35 ) 61 Clinical study of fluoxetine in improving the depression and neurological deficits of patients with stroke CHEN De-peng Objective To analyze the clinical effect of fluoxetine in improving depression and neurological function of patients with stroke.Methods From June 2013 to June 2014，81 cases of stroke patients in our hospital were randomly divided into observation group（40 cases）and control group（41 cases），patients in two groups were treated with conventional treatment of cerebral vascular disease，besides patients in the observation group were treated with fluoxetine.The improvement of depression and neurological function were compared between two groups before and after treatment，and adverse drug reactions were observed.Results The scores of depression and neurological function between two groups before treatment were not statistically significant（P＞0.05）.After treatment，depression score in the observation group was significantly lower than that in the control group，the difference was statistically significant（P＜0.05）；the neurological function defect score in the observation group was significantly lower than that in the control group（P＜0.05）.Patients in two groups did not have serious adverse drug reactions.Conclusion Fluoxetine can effectively relieve depression of patients with stroke，improve the degree of neurologic deficits.Clinical medication is safe and reliable and it is worth to clinical promoting and application. 2016 Vol. 23 (22): 61-63 [Abstract] ( 130 ) HTML (42 KB)  PDF  (0 KB)  ( 22 ) 64 Clinical efficacy of fine ureterocopic holmium laser lithotripsy for wite ureteral stones YANG Yi-min;CHEN Zhi-yang Objective To study the curative efficacy of fine ureteroscopic holmium laser lithotripsy for the treatment of ureteral calculi.Methods 150 cases of patients who were treated for ureteral calculi from June 2012 to June 2015 in our hospital were selected as the research objects，they were randomly divided into two groups，fine ureteroscope holmium laser group and pneumatic ballistic group，each group had 75 patients，after patients for 3-6 months follow-up，the surgery condition，the success rate of gravel，the incidence of complications of the two groups were compared.Results The operation time of fine ureteroscope holmium laser group was（35.6±6.3）min，the hospitalization time was（6.1±1.4）days；the operation time of pneumatic lithotripsy group was（53.4±8.1）min，the hospitalization time was（8.5±1.4）day，the operation time of fine ureteroscope holmium laser group，duration of hospitalization were significantly lower than those of the control group，and there were significant differences（P＜0.05）.The success rate of lithotripsy fine ureteroscope holmium laser group was 96.00%，which was significantly higher than that of pneumatic lithotripsy group of 85.33%，and there was a significant difference　（P＜0.05）.Fine lose uretroscopic holmium laser group for complication rate was 6.67%，which was significantly lower than that of air pressure ballistic group of 16.00%，with significant difference　（P＜0.05）.Ureteral stricture was not found in follow-up.Conclusion The efficacy of small ureter mirror holmium laser lithotripsy for the treatment of ureteral stones is high，simple and effective，security，with a certain advantages. 2016 Vol. 23 (22): 64-66 [Abstract] ( 151 ) HTML (36 KB)  PDF  (0 KB)  ( 33 ) 67 Effect analysis of ureteral occlusion device on ureteral calculus treated by holmium laser lithotripsy ZHANG Sui-bing;PAN Wei-bing;ZHU Bin Objective To explore the safety and effectiveness of ureteral occlusion device on ureteral calculus treated by ureteroscopic holmium laser lithotripsy.Methods Clinical data from 96 patients from May 2014 to August 2015 in our hospital with ureteral calculus treated by ureteroscopic holmium laser lithotripsy were retrospectively analyzed.Patients applied with ureteral occlusion device were classified into treatment group，and those without the device were categorized into control group.The stone clearance，operation time，hospital stay and hospitalization costs in both groups were compared.Results In comparison with stone clearance and operation time，there were statistical differences　［93.75%vs 83.33%；（22±5）min vs（40±3）min，P＜0.05］.Conclusion Ureteral occlusion device can remarkably reduce the occurrence of stone moving during surgery，increase stone clearance，shorten operation time，and enhance the success rate of ureteroscopic lithotripsy. 2016 Vol. 23 (22): 67-69 [Abstract] ( 148 ) HTML (40 KB)  PDF  (0 KB)  ( 34 ) 70 Diagnosis and treatment of 24 cases of testicular torsion CAI Bo-ji;LIN Fu-xiang Objective To improve the diagnosis and treatment of testicular torsion and testicular preservation ratio. Methods Patients who were diagnosised testicular torsion in 5 years from January 2011to December 2015，were retrospectively analyzed the clinical data of visited time，happened situation，age and prognosis.Results There were 24 cases of testicular torsion who had been diagnosised and treated at our hospital in 5 years.All were unilateral and the left side was more common than the right side.71%of patients were teenagers.Only 29%came to the hospital within 24 hours，and testicular preservation ratio was 71.4%.37.5%of the patients were misdiagnosed as testicular epididymitis before they came to out hospital，and delayed the timing of treatment.Conclusion Testicular torsion is the main reason for young people who lose thire testicle.Patients with low awareness of the disease and misdiagnosed ratio is high in the basic hospital.So enhancing the community education and improving the level of primary care physicians is an important measure to improving the diagnosis and treatment of disease and orchiopexy ratio. 2016 Vol. 23 (22): 70-72 [Abstract] ( 156 ) HTML (34 KB)  PDF  (0 KB)  ( 28 ) 73 The evaluation and analysis of the therapeutic value of hemodialysis in the treatment of uremic pruritus HU Yi-yang;SHEN Shi-zhong;WANG Jie Objective To study the therapeutic effect of hemodialysis in patients with uremic pruritus and uremia. Methods 100 cases of uremic pruritus and uremia′s patients from January 2013 to December 2015 who with treatment at the intrinsic phase in our hospital were selected as the study object，100 cases patients were divided into the control group and the observation group by taking the computer random grouping method，each group had 50 cases.The control group was implemented with hemodialysis in series hemodialysis filtration treatment，the observation group was implemented with blood perfusion in series of hemodialysis treatment.The total effective rate，skin itching disappeared time were compared between the two groups，and the β2-microspheres protein of the two groups was compared between before and after treatment.Results The total effective rate of the observation group was 94%，which was significantly higher than that of the control group（78%）（P＜0.05）.Compared with the control group，the disappearance time of skin itching in the observation group was significantly shorter（P＜0.05）.Compared with before treatment，the β2-microspheres protein of the two groups were significantly reduced after the treatment（P＜0.05），but after treatment，the β2-microspheres protein of the observation group was significantly lower than of the control group　（P＜0.05）.Conclusion In the clinical treatment of uremic patients with skin itching，the using of hemodialysis combined with blood perfusion treatment has significant clinical efficacy，it can effectively promote the relief of skin itching. 2016 Vol. 23 (22): 73-75 [Abstract] ( 164 ) HTML (44 KB)  PDF  (0 KB)  ( 24 ) 76 Clinical effect analysis of CyA combined with Cozaar in treating advanced IgA nephropathy SHI Wen-jian Objective To investigate the clinical effect and safety of CyA combined with Cozaar in treating advanced I-gA nephropathy.Methods 86 cases with advanced IgA nephropathy in our hospital from March 2014 to March 2015 were selected and divided into observation group and control group，43 cases in each group.Control group was given Cozaar treatment and observation group was given CyA combined with Cozaar.The 24-hour urinary protein quantity，serum creatinine，biochemical criterion and therapeutic response rate before and after treatment of the two groups were compared.Results After treatment，the 24-hour urinary protein quantity of the two groups were obviously lower than before treatment，and 24-hour urinary protein quantity of observation group was obviously lower than that of control group，the difference was statistically significant（P＜0.05）.Biochemical criterion and serum creatinine of the two groups were basically stable，the difference was not statistic significant　（P＞0.05）.Therapeutic response rate of observation group （95.34%）was obviously higher than that of control group　（65.11%），the difference was statistically significant　（χ2= 12.390，P＜0.01）.Conclusion CyA combined with Cozaar in treating advanced IgA nephropathy can effectively delay the progression，the total effect is better and adverse reaction rate is lower.It can be used as drug choice for IgA nephropathy. 2016 Vol. 23 (22): 76-78转96 [Abstract] ( 149 ) HTML (45 KB)  PDF  (0 KB)  ( 33 ) 79 Effects of open reduction and T-distal radius distal locking plate internal fixation treatment forpatients with distal radius fractures combined ulnar styloid fractures FANG Ming;WU Xiao-hang;YUAN Zhi-kun;LUO Ying Objective To investigate effects of open reduction and T-distal radius distal locking plate internal fixation for patients with distal radius fractures combined ulnar styloid fractures and the influence on wrist function.Methods 86 cases of patients with distal radius fractures combined ulnar styloid fracturesin in our hospital from May 2011 to April 2014 were randomly divided in to research group and control group　（closed reduction and external fixation），each were 43 cases.Excellent rate，changes of distal radius volar tilt，ulnar deviation and radial styloid height and complications were compared.Results The excellent rate of research group was 83.7%，which was higher than 62.8%of control group（P＜0.05）.After 6 months and 1 year，distal radius volar tilt，ulnar deviation and radial styloid heightof two groupshad no significant difference（P＞0.05）.Complications rate of research group was lower than of control group（P＜0.05）. Conclusion ORIF for patients with distal radius fractures combined ulnar styloid fractures has exact effect.It can effectively improve wrist function and reduce complications.It′s worthy of clinical widely used. 2016 Vol. 23 (22): 79-81 [Abstract] ( 142 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 82 The clinical efficacy of different artificial joint replacement for treatment of femoral neck fracture in elderly patients ZHANG Chuan-hui Objective To investigate the clinical effect of total hip replacement and half hip replacement for treatment of femoral neck fracture in elderly patients.Methods 78 cases of elderly patients with femoral neck fracture were selected as our subjects，who were hospitalize in our hospital from January 2009 to January 2013.They were randomly divided into A group（39 cases）and B group（39 cases）.The patients in A group were treated with total hip replacement and the patients in B group were treated with half hip replacement.The duration of operation，intraoperative blood loss，length of hospital stay and incidence of postoperative complication in both groups were recorded.The recovery of hip function in A group and in B group were compared in 1 year after operation.Results The duration of operation in A group［（98.5± 9.8）min］was longer than that of B group［（70.0±10.1）min］（P＜0.05）.The intraoperative blood loss in A group［（369.6± 125.0）ml］was more than that of B group［（259.0±104.3）ml］（P＜0.05）.The length of hospital stay in two groups had no significant difference（P＞0.05）.The incidence of postoperative complication was 33.3%（13/39）in A group and was 35.9%（14/39）in B group.There was no significant difference between two groups（P＞0.05）.Artificial joint dislocation occurred in 6 patient in A group and they were treated with closed reduction and traction under nerve blocking anesthesia.Acetab abrasion，pain and limited range of motion occurred in 7 patient and no artificial joint dislocation occurred in all patient in B group.The recovery of hip function in A group was superior to that in B group in 1 year after operation（P＜0.05）.Conclusion Total hip replacement and half hip replacement for treatment of femoral neck fracture have advantages respectively in elderly patients.Operation method should choose according to the specific condition of patients.Total hip replacement for treatment of femoral neck fracture can improve patient′s quality of life in elderly patients. 2016 Vol. 23 (22): 82-84 [Abstract] ( 126 ) HTML (40 KB)  PDF  (0 KB)  ( 14 ) 85 Anterior lumbar interbody fusion with stable-type self-locking plate cage benezech for the treatment of degenerative lumbar diseases TIAN Jian-bo;SU Ming-bao Objective To investigate the effectiveness of application of ALIF　（Anterior Lumbar Interbody Fusion）with stable-type self-locking PCB　（Plate Cage Benezech）in treatment of degenerative lumbar diseases.Methods A total of 46 patients with lumbar spondylolisthesis treated in our hospital from June 2012 to October 2014 were selected and randomly divided into two groups，with 23 cases in each group.And the two groups were treated with lateral rectus small incision，ALIF with stable-type self-locking PCB after extraperitoneal space approach and conventional PLIF（Posterior Lumbar Interbody Fusion）respectively.Pre-operative and post-operative symptoms and signs and post-operative complications were recorded；the post-operative bone graft fusion was reviewed and evaluated.The JOA　（Japanese Orthopaedic Association）scoring system was adopted for statistical analysis.Results The improvement rate of JOA and the incidence rate of complications in ALIF group was 85.79%and 13.04%respectively，which was better than those of PLIF group.The post-operative JOA scores between the two groups were statistically significant（P＜0.01）.Conclusion As a new minimally invasive surgical procedure，ALIF demonstrates its advantages of little trauma，excellent post-operative clinical effects，faster recovery，less complications and sequelaes in the treatment of lumbar degenerative diseases，and avoids the destruction of the posterior structure of the lumbar spine. 2016 Vol. 23 (22): 85-87 [Abstract] ( 158 ) HTML (38 KB)  PDF  (0 KB)  ( 36 ) 88 Clinical value of joint mobilization combined with muscle strength training after arthroscopic debridement of PFOA RAO Lai-sheng Objective To analysis clinical value of mobilization combined with muscle strengthened training for rehabilitation after arthroscopic debridement for patellofemoral osteoarthritis.Methods 100 cases of PFOA patients from January 2014 to December 2015 in our hospital were studied and divided into study group and control group according to random number table method，with 50 cases in each，control group received conventional flexion and extension strength training，knee joint activity training；on this basis，the study group received stability and patellofemoral joint mobilization，terminal extensor knee strength training，efficacy before and after treatment of patients of two groups were compared.Results Before treatment，1 months after treatment，the control group and the study group patients with Lysholm score was no significant difference（P＞0.05），3 months and 6 months after treatment，the Lysholm score and effect of study group were significantly better than that of control group　（P＜0.05）.Conclusion PFOA joint mobilization combined with muscle strength training after arthroscopic debridement，can significantly improve the knee joint function of patients，it is worth clinical promotion. 2016 Vol. 23 (22): 88-90 [Abstract] ( 124 ) HTML (38 KB)  PDF  (0 KB)  ( 23 ) 91 Effect and its evaluation of minimally invasive plate fixation in the treatment of ulnar fracture XU Jun-min;LIU Chang-zhi;XIAO Kai-min;HU Bin Objective To study the effect of minimally invasive plate fixation in the treatment of ulnar fracture.Methods From February 2013 to February 2015，100 patients with ulnar fractures admitted into our hospital were selected.By drawing lots，they were evenly divided into open reduction group and minimally invasive plate group.In the open reduction group，open reduction with plate fixation was adopted，while in the minimally invasive plate group，minimal way for plate fixation was used.The excellent and good rate of wrist joints and incidence of complications including postoperative infection，slippage of internal fixation，arthralgia，and delayed fracture healing were observed.The HHS score of elbow joint and Gartland-Werley score of wrist joint before and after surgery，operation time，hospital stay，and healing time were compared.Results Compared with the open reduction group，excellent and good rate in the minimally invasive plate group was higher accounting for 98.00%，while the rate was 74.00%in the former group with a statistical difference（P＜0.05）.In the minimally invasive plate group，the incidence of complications including postoperative infection，slippage of internal fixation，arthralgia，and delayed fracture healing was much lower，which was displayed a statistical difference（P＜0.05）.Before surgery，the HHS score of elbow joint and Gartland-Werley score of wrist joint were similar without statistical differences in both groups（P＞0.05）.After surgery，the HHS score and Gartland-Werley score were greatly improved compared with those before with statistical differences（P＜0.05）.The improvement in the minimally invasive plate group was much higher than that of open reduction group，with a statistical difference　（P＜0.05）.The operation time，hospital stay，and healing time in the minimally invasive plate group were much shorter in comparison with those in the open reduction group with statistical differences（P＜0.05）.Conclusion Minimally invasive plate fixation can obtain a definite effect on treating ulnar fracture at advantages of simple performance，small wound，and few postoperative complications，and can shorten hospital stay，accelerate bone fracture healing，and improve patient′s elbow joint and wrist joint functions，which is worthy of promotion. 2016 Vol. 23 (22): 91-93转105 [Abstract] ( 114 ) HTML (40 KB)  PDF  (0 KB)  ( 21 ) 94 Analysis of clinical value of cervus and cucumis polypeptide for injection in the treatment of limbs fracture HUANG Zhong Objective To observe and analyze the clinical effects of cervus and cucumis polypeptide for injection in the treatment of limbs fracture.Methods 80 patients with limbs fracture and who accepted treatments in our hospital from October 2012 to October 2014 were taken as the research objects，and according to the random number table method the patients were divided into the study group and the control group，40 cases in each group.In the control group，they were treated with the open reduction and internal fixation and were given the rountine symptomatic treatment，anti infection and limb function training guidance after the operation while in the study group，on the basis of the treatment in the control group，they were treated with the cervus and cucumis polypeptide for injection.Then，the treatment effects of the two groups were observed and compared.Results Two groups of patients after treatment，the VAS score in the study group was significantly lower than that of control group　（P＜0.01）；The fracture healing time of upper limbs and lower limbs in the study group were lower than those of control group　（P＜0.01）.The excellent rate in the study group was 92.5%，which was higher than that of control group of 72.5%（P＜0.01）.Conclusion The clinical effects of cervus and cucumis polypeptide for injection in the treatment of limbs fracture are definite，which can accelerate the healing of the fracture site and improve the prognosis in the great extent，thus it is worthy to be applied and promoted in the clinical. 2016 Vol. 23 (22): 94-96 [Abstract] ( 132 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 97 Application value exploration of small-incision dual Endobutton titanium plates on repair and reconstruction of coracoclavicular ligament in acromioclavicular dislocation ZHONG Ling-jian;DING Yi-yun;ZHANG Gan-sheng;CHEN Yan-zhen;LAI Xiao-rong Objective To explore the clinical application of small-incision dual Endobutton titanium plates on repair and reconstruction of coracoclavicular ligament in acromioclavicular dislocation.Methods From April 2012 to September 2015，106 cases with acromioclavicular dislocation were selected as research objects.They were randomly divided into observation group and control group.In the observation group，repair and reconstruction of coracoclavicular ligament in acromioclavicular dislocation was realized by small incision with dual Endobutton titanium plates，while in the control group，clevicular hook plote was adopted.Follow-up visits after surgery at regular intervals were needed，and postoperative recovery in both groups was compared.Results The average follow-up visits after surgery was from 8 to 24 months. In the observation group，the excellent and good rate of functional recovery was 94.34%，and the rate in the control group was 75.47%，with a statistical difference（P＜0.05）.Before surgery，there was no great difference in VAS score，coracoclavicular distance，and acromioclavicular translocation distance in the two groups（P＞0.05）.During the last time follow-up visit after surgery，the VAS score，coracoclavicular distance，and acromioclavicular translocation distance in the observation group were all superior to those in the control group with statistical differences（P＜0.05）.Conclusion Application of small-incision dual Endobutton titanium plates on repair and reconstruction of coracoclavicular ligament in acromioclavicular dislocation is safe and effective approach can obtain a favorable clinical effect. 2016 Vol. 23 (22): 97-99 [Abstract] ( 117 ) HTML (38 KB)  PDF  (0 KB)  ( 18 ) 100 Comparison curative effectiveness of two internal fixation methods for treatment of femoral intertrochanteric fractures in aged patients HUANG Kai;CHEN Ye-guang;WANG Yan-bo;TIAN Tao;GAO Ding Objective To explore curative effectiveness of proximal femoral nail（PFNA）and proximal femoral locking plate　（PFLCP）for treatment of femoral intertrochanteric fractures in aged patients.Methods 66 patients hospitalized in our department of elderly femoral intertrochanteric fracture（aged over 60 years old）from January 2013 to August 2014 were randomly divided into two groups and were treated with PFNA or PFLCP.The operation time，bleeding volume，clinical healing time，internal fixation complication rate and the last follow-up Harris score of the two groups were compared.Results All 66 patients were followed up for 12-20 months.The operation time，bleeding volume，clinical healing time，internal fixation complication rate and the last follow-up Harris score of the PFNA group were　（61.7±11.8）min，（78.1±18.7）ml，（7.34±1.18）weeks，3.13%，90.6%and PFLCP group were　（62.8±9.7）min，（111.2±28.6）ml，（9.74±1.71）weeks，8.82%，70.6%.There was no statistically significant difference in the operation time and the incidence of complication between the two groups（P＞0.05）.But the patients with treatment of PFNA got fewer intraoperative blood loss，shorter fracture healing time and better functional recovery of hip joint（P＜0.05）.Conclusion PFNA internal fixation has the advantages of small trauma，quick healing，and earlier weight bearing，it is the better choice for the treatment of elderly femoral intertrochanteric fractures. 2016 Vol. 23 (22): 100-102转115 [Abstract] ( 147 ) HTML (42 KB)  PDF  (0 KB)  ( 19 ) 103 Clinical effects comparison of locking proximal humerus plate and traditional steel plate in treating proximal humeral fractures YANG Zheng-yan;LI Zong-ze;HU Hai-quan;HU Guo-hua;YANG Cheng-gang Objective To explore the clinical effects of locking proximal humerus plate and traditional steel plate in treating proximal humeral fractures.Methods 56 proximal humeral fractures patients treated from May 2014 to February 2016 of our hospital were selected and were divided according to random draw principle.28 patients in treatment group were used locking proximal humerus plate and 28 patients in control group were used traditional steel plate.Excellent rate of fracture healing，healing time and incidence rate of complications in two groups were compared.Results The excellent rate of fracture healing，incidence rate of complications and fracture healing time in treatment group were respectively 92.8%，21.4%and　（11.5±2.4）weeks，which were respectively 75.0%，7.1%and　（15.9±3.1）weeks in control group，with the significant differences（P＜0.05 or P＜0.01）.Conclusion Compared with traditional steel plate operation，locking proximal humerus plate in treating proximal humeral fractures has more advantages，which can promote the healing process，decrease the complications during rehabilitation period，with safe and reliable，and has promotion significance. 2016 Vol. 23 (22): 103-105 [Abstract] ( 128 ) HTML (36 KB)  PDF  (0 KB)  ( 38 ) 106 Clinical study of Kang′ai injection combining with CEF in sequence and docetaxel for chemotherapy in the treatment of breast cancer CHEN Feng-wu Objective To explore the clinical effect of Kang′ai injection combining with chemotherapy on treating breast cancer.Methods From February 2012 to February 2015，50 patients with breast cancer admitted into our hospital were selected，and evenly divided into two groups based on the sequence of admission to hospital.In observation group，Kang′ai injection combining with cyclophosphamide-epirubicin-fluorouracil（CEF）in sequence and docetaxel for chemotherapy was provided，while in control group，only CEF in sequence and docetaxel was used.The clinical therapeutic effect and quality of life（QOL）in both groups were compared.Results There was no great difference in total therapeutic effective rate in both groups as well as clinical effect in inter-group comparisons（P＞0.05）.The effective rate of QOL in the observation group was 96.00%，much higher than 60.00%in the control group with statistical difference（P＜0.05）.In the observation group，the incidence of adverse drug reaction　（ADR）was 24.00%，greatly lower than 60.00%in the control group with statistical difference（P＜0.05）.Conclusion Combination of Kang′ai injection with chemotherapy can obtain a remarkable effect in breast cancer patients after surgeries.It can alleviate the adverse reactions caused by chemotherapy drugs and reduce the leukopenia，which is safe and effective，and it is worthy of clinical promotion. 2016 Vol. 23 (22): 106-108 [Abstract] ( 132 ) HTML (37 KB)  PDF  (0 KB)  ( 8 ) 109 Application effect of intestinal metal stent in the patients with left hemicolon carcinoma complicated with obstruction under colonoscopy LIU Xue Objective To explore the application effect of intestinal metal stent in the patients with left hemicolon carcinoma complicated with obstruction under colonoscopy.Methods 15 patients with left hemicolon carcinoma complicated with obstruction who were admitted to our hospital from March 2015 to March 2016 were selected as observation group.They were given intestinal metal stent under colonoscopy to alleviate obstruction，and they were further given surgery to remove the tumor.Another 15 patients with left hemicolon carcinoma complicated with obstruction who were admitted to our hospital from January 2014 to December 2014 were selected as control group. They were given colostomy to alleviate obstruction，and they were further given surgery to remove tumor.The surgical effects were observed in both groups.Results After implantation of metal stent，abdominal girth，gastrointestinal decompression volume，and maximum transverse diameter of proximal colon in observation group were respectively reduced compared with that before the surgery（P＜0.01）；abdominal pain，abdominal distention and other symptoms in observation group were all significantly reduced，recovery time of borborygmus was　（3.3±0.6）d，and the complete remission time of intestinal obstruction was　（8.6±0.3）d.All the patients were given laparotomy，and dilation or edema was not observed in the intestines during the surgery.No significant feces were observed in the intestinal tract. Postoperative anastomotic fistula and incision infection were not observed in the patients，who were recovered after phaseⅠconservative treatment of resection and anastomosis；Postoperative anastomotic fistula and other complications were not observed in the observation group.The incidence rate of anastomotic fistula in the control group was 20.0%，and the incidence rate of complications was 33.3%.The observation group was significantly lower than the control group with statistical difference（P＜0.05）.Expense of hospitalization in the observation group was（14 963.9±1563.7）yuan，and the length of stay was（17.9±2.2）d.Expense of hospitalization in the control group was（29 613.7±3697.2）yuan，and the length of stay was　（31.6±5.9）d.In the comparison between groups，it has statistical difference（P＜0.01）.Conclusion Surgery after removal of obstruction by intestinal metal stent under colonoscopy is able to achieve phaseⅠ resection，and reduce the incidence rate of anastomotic fistula and complications，which is helpful for alleviating patients′economic burden. 2016 Vol. 23 (22): 109-111 [Abstract] ( 167 ) HTML (43 KB)  PDF  (0 KB)  ( 17 ) 112 Research and practice of end-of-life care for cancer patients based on JCI standards ZHAO Chang-lin;PENG Lin-ji;ZHANG Tao;GU Wei-hong;LI Ling-yan;BAO Dan-yan Objective To provide and improve the quality of end-of-life care for advanced cancer patients，the Joint Commission International Accreditation Standards（JCI standards）for hospitals was applied in the practice of palliative care for patients with advanced cancer.Methods A set of systemic，complete and continuously-improving end-of-life care processes were developed and a system for evaluating and providing end-of-life care for advanced cancer patients was formulated and carried out.Based on the processes and the system and the constant improvements made to them with PDCA method，end-of-life care was provided to 900 inpatients from January 2010 to December 2015.Results The result showed that the overall terminally ill patient satisfaction reached 99.5%.Conclusion The JCI standards-based end-of-life care for advanced cancer patients can improve the overall quality of care at the end of life and patient satisfaction.Therefore，it is a relatively good model of palliative care at the present time. 2016 Vol. 23 (22): 112-115 [Abstract] ( 144 ) HTML (45 KB)  PDF  (0 KB)  ( 15 ) 116 Clinical combined application of uterine artery embolization with cisplatin and paclitaxel chemotherapy in locally advanced cervical cancer patients ZHANG Shu-zhen;YANG Mei;ZENG Chun-jie;WANG Guo-dong Objective To investigate the clinical combined application of uterine artery embolization with cisplatin and paclitaxel chemotherapy in the treatment of locally advanced cervical cancer patients.Methods Retrospectively analized 152 cases locally advanced cervical cancer patients in our hospital from January 2006 to June 2013.54 cases were combined treated by uterine artery embolization with cisplatin and intravenous chemotherapy（artery+vein group），while 52 cases were treated with uterine artery embolization with cisplatin（artery group），and 46 cases received intravenous chemotherapy（vein group）.Patients were treated with paclitaxel combined with cisplatin，paclitaxel 135 mg/m2and cisplatin 70 mg/m2，and received radical uterus resection surgery and lymph node dissection or radiation therapy after 1-2 courses.The clinical efficacy and adverse reaction，completion rate of the surgery，blood loss，the operation time，resection margin negative rate and postoperative 3 years survival rate of patients were observed.Results The tumor size of artery+ vein group and artery group were significantly reduced.5 cases of intravenous group had disease progression.The total effective rate of the artery+vein group and artery group were higher than that of intravenous group with statistical difference（P＜0.05）.There were 47cases，44 cases and 30 cases underwent uterine resection surgery and lymph node dissection in artery+vein group，artery group and intravenous group respectively with statistical difference（P＜0.05）.Operation time of artery+vein group and artery group were　（180.1±40.4），（180.2±30.3）min，shorter than　（210.4±30.2）min of intravenous group with statistical difference（P＜0.05）.Blood loss of artery+vein group and artery group were（265.6±50.2），（280.2±55.1）ml，less than （350.6±45.7）ml of intravenous group with statistical difference（P＜0.05）.The resection margin negative rate of the two groups was significantly higher than that of intravenous group with statistical difference（P＜0.05）.All patients were alive and without recurrence for 3 years after operation.Conclusion Cisplatin uterine artery embolization combined with paclitaxel intravenous chemotherapy can retain the advantages of uterine artery embolization chemotherapy，and reduce the adverse reactions.It is a better way to the neoadjuvant chemotherapy for locally advanced cervical cancer. 2016 Vol. 23 (22): 116-119 [Abstract] ( 135 ) HTML (45 KB)  PDF  (0 KB)  ( 33 ) 120 Clinical application study of Bakri uterine packing balloon catheter in cesarean section with previa placenta HUANG Qing;LAI Jun;YANG Gang;WANG Yun-xia Objective To explore the clinical application effect of Bakri uterine packing balloon catheter in cesarean section with previa placenta.Methods 40 pregnant women in obstetrics and gynecology department of our hospital from February 2014 to February 2016 were selected and randomly divided into the control group and the observation group，20 cases in each group.The control group was given conventional hemostatic treatment，the observation group was given Bakri uterine packing balloon catheter to stop bleeding.The operation time，the success rate of operation，the efficiency of hemostasis，the rate of hysterectomy and the amount of bleeding after operation for 24 hours in the two groups was compared.Results The operation time of the observation group was shorter than that of the control group，the amount of bleeding after operation for 24 hours in the observation group was less than that in the control group，with significant difference　（P＜0.05）.The success rate of surgery，bleeding rate of the observation group was higher than that of the control group，the rate of hysterectomy in the observation group was lower than that in the control group，with significant difference（P＜0.05）.The effectual time of the observation group was shorter than that of the control group，with significant difference　（P＜0.05）.Conclusion Bakri uterine packing balloon catheter can effectively reduce the amount of bleeding，improve the success rate of operation，shorten the operation time and reduce the rate of hysterectomy，it is worthy of clinical promotion and application. 2016 Vol. 23 (22): 120-122 [Abstract] ( 107 ) HTML (38 KB)  PDF  (0 KB)  ( 20 ) 123 Clinical analysis of pregnancy outcome of pregnancy complicated with heart disease of different heart function LI Xia Objective To explore the influence of different cardiac function of pregnancy complicated with heart disease on pregnancy outcome.Methods 220 cases of pregnancy complicated with heart disease in our hospital from January 2011 to January 2016 were selected as the subjects of this study，the influence of different cardiac function on pregnancy outcome was studied.Results In this research，the condition of pregnancy complicated with heart disease was mainly manifested as cardiac arrhythmias and congenital heart disease，including 98 cases of pregnancy complicated with cardiac arrhythmias，which accounted for 44.55%，73 cases of pregnancy complicated with congenital heart disease，which accounted for 33.18%，the third was pregnancy with rheumatic heart disease patients，the others accounted for 10.91%.Further analysis，the cardiac function in patients with pregnancy complicated with arrhythmia was grade 1-2，in pregnancy with congenital heart disease patients，the grade of cardiac function both existed，among them，grade 1-2 were mostly.In this study，there was 1 patients with Eisenmenger′s syndrome during pregnancy，suddenly died in 5 d after delivery.There were 8 cases of patients with hypertensive heart disease，cardiac function was grade 3-4，there was no death patients.There were 15 cases of patients with perinatal cardiomyopathy，and the cardiac function was grade 4. Gestational week in different levels of cardiac function in patients with pregnancy was compared，the gestational week in the higher level of the heart function of pregnancy was shorter than that in the low level of pregnancy，with significant difference（P＜0.05），and the iatrogenic premature birth and perinatal mortality were significantly increased.Conclusion Patients with hypertensive heart disease，congenital heart disease and heart disease with cardiac function more than grad 3-4 were more common in the clinical center，which can increase the incidence rate of iatrogenic preterm labor and increase the mortality rate of pregnant women and perinatal infants.In this study，the heart function status of pregnant women with heart disease is closely related with the maternal and perinatal outcomes，which should be given attention in clinical. 2016 Vol. 23 (22): 123-125 [Abstract] ( 133 ) HTML (35 KB)  PDF  (0 KB)  ( 28 ) 126 Clinical analysis of main sacral ligament complex and pubovaginalis cross suture in the treatment of 36 cases of uterine prolapse and anterior vaginal wall bulge CHEN Yuan-hong;YAN Cai-xia;FENG Shu-mei;CHEN Shao-hui;LI Hai-jing Objective To explore the curative effectiveness of main sacral ligament complex and pubovaginalis cross suture in the treatment of uterine and anterior vaginal wall prolapse.Methods Altogether 36 cases of the uterine prolapse complicated with the anterior vaginal wall bulge in our hospital from August 2012 to December 2014 were selected as the research group，which were treated with vaginal hysterectomy combined with main sacral ligament complex and pubovaginalis cross suture　（combined with repair of posterior vaginal wall and repair of perineal laceration）.Post-operational subjective and objective curative effectiveness of patients was analyzed，including perioperative conditions and complications.Results Surgeries of 36 cases of patients were successfully completed.Postoperative POP-Q scores in each position increased significantly compared with the pre-operative one and reached anatomical reduction（P＜0.01）.All POP-Q scores in indication sites were significantly improved compared with the preoperative one.Among all the cases，34 cases of POP-Q scores were at degree 0，only 2 cases of POP-Q scores were at degreeⅠ（pre-operative POP-Q score：Ⅳdegree）.The objective curative rate was 100%，and the subjective satisfaction rate was 100%.Conclusion The main sacral ligament complex and pubovaginalis cross suture demonstrates great effectiveness in the use of self-organization in the treatment of anterior pelvic defects and its easy-to-operate features with strong practicality，low medical expenses and recurrence rate. 2016 Vol. 23 (22): 126-129 [Abstract] ( 128 ) HTML (47 KB)  PDF  (0 KB)  ( 40 ) 130 Result analysis of cervical lesions in 8000 women after physical examinations in Enping ZHENG Ming-fang Objective To get known the situation of women′s cervical lesions in Enping in order to find out the optimal approach to detect cervical lesion.Methods From December 2005 to April 2016，8000 women for physical examinations in our hospital were selected as research objects and were provided with regular gynecological examinations which included cervical smear cytological examinations containing Thinprep cytologic test（TCT）or Pap smear and high-risk human papilloma virus（HPV）detection.Those women whose cervical cytological examinations were abnormal were provided with colposcopy and histopathologic examination aiming at observing cervical lesions.Results Among 8000 women′s physical examinations，cervical lesions were in 4576 cases accounting for 57.2%.There were 4232 women underwent TCT examinations，and 147　（3.5%）cases were in abnormal.The rest cases were through Pap smear examinations，and 56　（1.5%）cases were in abnormal.The sensitivity and positive rate of TCT were both higher than those by Pap smear，with significant difference（P＜0.05）.Among 4576 cases with colposcopy，normal images were 1934 cases and the number of detecting cervical intraepithelial neoplasia（CIN）was 208 cases.Abnormal images were 2642 cases，and 2218 ones were detected with CIN.HPV detection was performed in 3127 cases，and 532 cases were in positive accounting for 17.0%.The rate of cancerization in abnormal patients after TCT examinations was 12.9%，which was higher than that in HPV positive patients accounting for 3.3%，with significant difference（P＜0.05）.Conclusion In regular gynecological examinations，HPV combining with TCT examination can be used to detect cervical lesions and cervical cancer at an early stage as well as reduce the incidence rate of cancerization. 2016 Vol. 23 (22): 130-132转135 [Abstract] ( 116 ) HTML (45 KB)  PDF  (0 KB)  ( 28 ) 133 Effect of orthodontic and repair combination therapy in patients with dentition defect with teeth micromaxillary deformity WANG You-mei Objective To investigate the clinical effect of orthodontic treatment combined with restoration of dentition defect with dental deformity.Methods From September 2014 to September 2015，48 patients with dentition defect in our hospital treated with dentition defect were selected as the study object.The clinical data of all patients were completed. The patients were randomly divided into observation group and control group，24 cases in each group.Patients in the control group were given routine treatment；Patients in observation group were treated with repair and orthodontic treatment，and the treatment effect of the two groups were observed and compared.Results The excellent treatment rate of observation group was 95.8%（23/24），higher than 83.3%（20/24）in the control group，the difference was statistically significant（P＜0.05）.The rate of recovery and treatment satisfaction rate of the patients in the observation group was higher than that in the control group respectively，the difference was statistically significant（P＜0.05）.Conclusion In the treatment of dentition defect with dental deformity，the cure rate is high，the effect is remarkable，and it is worth popularizing. 2016 Vol. 23 (22): 133-135 [Abstract] ( 133 ) HTML (37 KB)  PDF  (0 KB)  ( 28 ) 136 Clinical effect of different crown-to-implant ratio for single short implant restoration in the posterior region WANG Ting-ting;WANG Yuan-qin Objective To observe the clinical effects on posterior region of the crown root ratio（CIR）of different short implants.Methods 97 patients with 154 short implants of single-restoration in posterior from December 2011 to March 2013 were included in the study.All were divided into 3 groups by its CIR:group A0≤CIR≤1.0，group B 1＜CIR＜2.0，group C CIR≥2.0.During 36 months after restoration，the patients were detected cumulative survival rate，mechanical complication and marginal bone level around the implant.Results During the follow-up period of 3 years，the cumulative survival rate of 154 short implants was 95.4%，and there was no significant difference among the groups（P＞0.05）.There was no significant difference in mechanical complications and marginal bone level around the implant among the groups （P＞0.05）.Conclusion Remaining posterior area different CIR short implant rate had no significant difference，can obtain good clinical effect，but the long-term effect remains to be seen. 2016 Vol. 23 (22): 136-140 [Abstract] ( 142 ) HTML (55 KB)  PDF  (0 KB)  ( 41 ) 141 The efficacy and safety of valproic acid sodium，topiramate and levetiracetam in treating epilepsy in children LIU Li-ying;XIAO Shan;LIU Chun-mei;SHU Jian;GUO Chun-yu;CHEN Chun-lian;LIU Kang Objective To evaluate the single drug efficacy and safety of valproic acid sodium，topiramate and levetiracetam in treating epilepsy in children.Methods 150 cases of children with epilepsy who were new diagnosised and treated in outpatient service of epileptic specialized object in our hospital from June to December 2015，were randomly divided into three groups，50 cases in each group，respectively given valproate acid sodium（group A），topiramate（group B）and levetiracetam （group C）.The seizures，curative effect and adverse reaction of the three groups of drug treatment were recorded and observed.Results The total effective rate of group A was 88.0%；group B was 84.0%；group C was 86.0%.There was no statistically significant difference among the three groups（P＞0.05）.The incidence of adverse reactions in group A was 28.0%，30.0%in group B，and 26.0%in group C，there was no statistically significant difference among the three groups（P＞0.05）.Conclusion Valproate acid sodium，topiramate and levetiracetam in monotherapy has no difference between the efficacy and safety of children epilepsy. 2016 Vol. 23 (22): 141-143 [Abstract] ( 160 ) HTML (38 KB)  PDF  (0 KB)  ( 26 ) 144 Effects observation of atorvastatin combined with trimetazidine in treating chronic heart failure NIE Fu-gen;OUYANG Xian-guo;CHEN Qin;HUANG Ying Objective To observe the clinical effects of atorvastatin combined with trimetazidine in treating chronic heart failure.Methods 54 chronic heart failure patients from January to June 2015 of cardiology department in our hospital were selected.Patients were randomly divided into control group and observation group，and each group was 27 cases.All patients in two groups were given atorvastatin on the basis of routine anti-heart failure treatment.Patients in observation group were further given trimetazidine.After treatment for 6 months，the treatment effective rate，cardiac function monitoring indicators including heart rate，left ventricular ejection fraction，6-minute walk distance and plasma atrial natriuretic peptide concentration，adverse effects in two groups were compared.Results After treatment for 6 months，the total effective rate in control group and observation group was respectively 85.2%and 96.3%，the total effective rate in observation group was obvious better than that of control group and the difference was statistical significance（P＜0.05）.The heart rate，left ventricular ejection fraction，6-minute walk distance and plasma atrial natriuretic peptide concentration in two groups was improved than before treatment respectively，and the improvement degree in observation group was obvious better than that of control group（P＜0.05）.Any adverse effects appeared in two groups during the 6 months treatment.Conclusion The effects of atorvastatin combined with trimetazidine in treating chronic heart failure is better than single uses of atorvastatin and which with wide clinical application prospect. 2016 Vol. 23 (22): 144-146 [Abstract] ( 159 ) HTML (37 KB)  PDF  (0 KB)  ( 37 ) 147 Observation of treatment effect for modified Maxingshigan decoction in post-cold cough OU Shen-en;WU Jing-sheng;YANG Gen-wang;LI Qun-feng Objective To observe the treatment effects of modified Maxingshigan decoction combined with Western medicine in the treatment of post-cold cough.Methods The 96 patients of post-cold cough from May 2015 to March 2016 in our hospital were randomly divided into two groups.The control group was 46 cases and was treated by the routine treatment with Western medicine.The observation group was 48 cases and was treated by modified Maxingshigan decoction on the basis of control group.The treatment effects of two groups were compared after two courses of treatment.Results The cough symptom scores of two groups after treatment were significantly reduced（P＜0.01），the symptom scores of the observation group after treatment of one week and two weeks were lower（P＜0.01）.The total efficient rate was 89.58%for the observation group.The total efficient rate was 78.26%for the control group.The difference in contrast with two groups had height statistically significance（P＜0.01）.Conclusion The treatment effects of modified Maxingshigan decoction combined with Western medicine for post-cold cough are apparently superior to the pure Western medicine treatment. 2016 Vol. 23 (22): 147-149 [Abstract] ( 167 ) HTML (41 KB)  PDF  (0 KB)  ( 18 ) 150 The analysis of Rhizoma coptidis flat stomach soup treatment efficacy in 112 cases of chronic gastritis taste hot and humid HUANG Guo-dong Objective To study the analysis of Rhizoma coptidis flat stomach soup effect in the treatment of chronic gastritis taste hot and humid.Methods 112 patients with chronic gastritis taste hot and humid from January 2015 to January 2016 in our hospital were selected.They were randomly divided in two groups，study group and control group，56 cases in each group.Patients in the control group were given conventional therapy，the study group based on the control group was added with Rhizoma coptidis flat stomach soup treatment.The clinical efficacy of two groups was compared. Results The patients′clinical total effective rate of study group was 94.64%，higher than 67.86%in control group with statistical difference（P＜0.05）.Conclusion Using Chinese Rhizoma coptidis flat stomach soup treated patients with chronic gastritis taste hot and humid has significantly effect.It can be widely used in clinic. 2016 Vol. 23 (22): 150-151转154 [Abstract] ( 134 ) HTML (33 KB)  PDF  (0 KB)  ( 6 ) 152 Infection factors and drug resistance analysis of multi-drug resistant Pseudomonas aeruginosa LI Yong-wei;LIU Xin-wei;WANG Chun-xia;ZHANG Xiao-qian;GUO Xiao-lan Objective To explore the infection situation and features of multi-drug resistant Pseudomonas aeruginosa in our hospital and to provided basis for clinical infection control.Methods BioMerieux VITEC2-Compact automatic microbiology analysis system was applied to identify and to conduct the drug sensitive test.The drug resistance and clinical materials of 95 strains of multi-drug resistant Pseudomonas aeruginosa separated from clinical samples from January 2013 to January 2015 were analyzed.Results 78.9%（75/95）of the 95 strains of multi-drug resistant Pseudomonas aeruginosa were separated from sputum samples，followed by secretion of wounds（10.5%，10/95）.Trachea intubation，deep venous cannula，and trauma wound were significant infection factors.Drug sensitivity results showed that the drug resistance of ceftriaxone was over 95.00%，and the resistance rate of ceftazidime was 36.30%.Conclusion Infection of multidrug resistant Pseudomonas aeruginosa is related to various invasive catheters and instrumental examinations.Therefore，in the treatment of trauma，effective infection control measures should be formulated to conduct continuous drug resistance monitoring and isolation of those infected with Pseudomonas aeruginosa and to control the spread and prevalence of multi-drug resistant Pseudomonas aeruginosa. 2016 Vol. 23 (22): 152-154 [Abstract] ( 137 ) HTML (33 KB)  PDF  (0 KB)  ( 34 ) 155 Study of anxiety and its influencing factors for parents of children with hypospadias XU Hui-ping;LI Run-zuan;LIU Si-si Objective To explore the anxiety and its influencing factors for the parents of children with hypospadias. Methods 180 cases of parents of children who accepted urethra hypospadias surgery in Foshan Maternal and Child Health Care Hospital from December 2012 to December 2014 were selected as study group.Self-rating anxiety scale （SAS）and self-designed general situation questionnaire were adopted to conduct a questionnaire survey for parents of children with hypospadias.Results The anxiety score of parents of children with hypospadias was（53.41±9.85）points，which was higher than that of the national norm，with significant difference　（t=31.736，P＜0.01）.Mother′s anxiety score was higher than that father′s.Parents with lower education level obtained higher anxiety scores.The family monthly income was lower，higher anxiety scores were achieved.Parents who were at their own expense had higher anxiety scores than that parents not at their own expense.Parents with less understanding of the operation mode had higher anxiety scores.Parents whose children′urethral mouth was located in scrotum and penis junction（gradeⅢ）and urethral mouth located in perineal position　（gradeⅡ）had higher anxiety scores than that the other two types.Conclusion The anxiety scores of parents of children with hypospadias are higher than that of the domestic norm and，which are affected by the parental role，awareness of the operation mode and the disease type and so on. 2016 Vol. 23 (22): 155-157 [Abstract] ( 166 ) HTML (34 KB)  PDF  (0 KB)  ( 25 ) 158 Analysis of comprehensive nursing care for post-BillrothⅡ gastrectomy patients with bile duct stones undergoing ERCP FU Feng-xiu;YAN Li-min Objective To study the clinical effect of application of comprehensive nursing care for post-BillrothⅡgastrectomy patients with bile duct stones undergoing endoscopic retrograde cholangiopancreatography（ERCP）.Methods 88 patients who suffered from bile duct stones after BillrothⅡ gastrectomy in our hospital from November 2013 to November 2015 were selected and divided into control group and observation group according to the random number table method，44 cases in each group.The routine surgical nursing mode was administered for patients in control group during ERCP；patients in observation group were nursed by using the comprehensive nursing mode during ERCP.The satisfaction rate，the total length of hospitalization for treatment of bile duct stones and the patients with adverse reactions of two groups were compared.Results For post-BillrothⅡ gastrectomy patients with bile duct stones undergoing ERCP in observation group，satisfaction rate of the nursing service was 95.5%，higher than that was 77.3%of control group；the total length of hospitalization for treatment of bile duct stones in the hospital in observation group was（7.69± 1.08）d，significantly shorter than that was（11.50±2.86）d of control group；patients with adverse reactions during ERCP in observation group was 1 case，significantly less than that was 7 cases of control group.Conclusion The application of comprehensive nursing care for post-BillrothⅡ gastrectomy patients with bile duct stones undergoing ERCP has proved its obvious clinical effectiveness. 2016 Vol. 23 (22): 158-160 [Abstract] ( 121 ) HTML (36 KB)  PDF  (0 KB)  ( 26 ) 161 Comprehensive nursing intervention in massive ascites concentration and autologous transfusion LIU Guo-ping Objective To explore the clinical characteristics of comprehensive nursing intervention in massive ascites concentration and autologous transfusion.Methods 92 patients who were treated with massive ascites concentration and autologous transfusion from March 2014 to March 2016 in the hospital were selected and randomly divided into two groups according to the random number method，with 46 cases in each group.The basic nursing was performed for patients in control group；while，observation group was treated with comprehensive nursing intervention.The improvement of clinical symptoms and renal functions，the quality of life and negative emotions of two groups were compared.Results The weight［（57.67±10.69）kg］，waist circumference［（92.45±5.61）cm］of observation group was less than that was［（67.56± 13.66）kg］，［（99.67±8.43）cm］of control group，the 24 h urine［（1914.39±226.67）ml］of observation group was more than that was［（1014.56±208.84）ml］of the control group；the glomerular filtration rate（GFR），serum creatinine and HbA1clevel was（78.56±28.56）ml/min，（92.56±14.67）μmol/L，（6.23±2.07）%versus（95.67±31.67）ml/min，（74.67±24.69）μmol/L and （5.43±1.32）%in control group with statistical difference（P＜0.05）.The overall score of observation group　［（19.43±6.63）score］was also significantly higher than that was（14.54±4.84）score of control group with statistical differences（P＜0.05）.The self-rating depression scale（SDS）and self-rating anxiety scale（SAS）of observation group after post-operative nursing was（60.44±1.11）score，（55.31±3.47）score，was respectively higher than that was（66.34±3.14）score，（64.51± 11.34）score of control group with statistical differences（P＜0.05）.Conclusion Comprehensive nursing intervention plays an important role in the whole process of massive ascites concentration and autologous transfusion，which can effectively control the patients′clinical symptoms，speed up the pace of rehabilitation for patients，improve the quality of clinical nursing，and further improve the patients′quality of life. 2016 Vol. 23 (22): 161-163 [Abstract] ( 120 ) HTML (45 KB)  PDF  (0 KB)  ( 36 ) 164 The observation of the effect in painless gastroscopy with two kinds of care model joint program LIU Jin-xiu;LIU Cui-ling;OU Jie-di Objective To observe the effect in painless gastroscopy with two kinds of care model joint program.Methods 80 patients with routine gastroscopy painless from September 2014 to October 2015，they were divided into the study group and the control group according to a random number table.The study group were treated with quality care combined with psychological care，the control group were treated with routine care.After treatment，the blood pressure and heart rate，SAS score，nursing satisfaction and complication rates of the two groups were recorded and compared. Results After treatment，the study group of patients with systolic blood pressure，diastolic blood pressure，heart rate were （131.2±5.6）mmHg，（78.3±5.6）mmHg，（79.7±4.7）/min，compared with the（137.9±6.3）mmHg，（89.5±5.8）mmHg，（89.6±5.2）/min in control group，the difference were statistically significant（t=5.0272，8.7860，8.9329，P＜0.01）；after treatment，the two groups of patients with the SAS scores was significantly lower than before treatment respectively，while the study group of patients with SAS scores［（35.56±1.42）scores］was significantly lower than（40.68±0.81）scores in the control group，the difference was statistically significant（P＜0.01）；the study group patients satisfaction with care was significantly higher than that of the control group，the difference was statistically significant（χ2=4.1143，P＜0.05）；the study group patients with respiratory depression，nausea，vomiting and other complication rate was 5.0%，lower than 40.0%in the control group，the difference was statistically significant（χ2=14.0502，P＜0.05）.Conclusion Psychological quality care combined with nursing intervention can significantly improve painless gastroscopy patient anxiety，it can stability patient′s heart rate and blood pressure. 2016 Vol. 23 (22): 164-166 [Abstract] ( 154 ) HTML (41 KB)  PDF  (0 KB)  ( 37 ) 167 The effect of positive nursing on stress reaction in surgical patients LUO Yu-lan;PENG Shu-fang;XIE Li-juan Objective To analyze the effect of positive nursing intervention on stress response of surgical patients. Methods 110 patients with surgical surgery in our hospital from March 2014 to January 2016 were selected as the research object，and were divided into observation group and control group according to used of nursing intervention measures different.56 cases of patients in observation group were used sex hinted nursing method for intervention guide，54 cases of patients in control group with routine nursing intervention measures.The stress reaction of the two groups were observed and compared.Results The rate of heart and blood pressure of the two groups before operation 1 d were compared，the difference was not statistically significant（P＞0.05）.The rate of heart and blood pressure in the observation group was statistically better than that of control group（P＜0.05）.The operation time of the two groups were compared，the difference was not statistically significant（P＞0.05）.The postoperative pain and nursing satisfaction of the observation group was better than that the control group respectively，the difference was statistically significant（P＜0.05）.Conclusion For surgical patients with positive effect of nursing care，can effectively alleviate the stress response of patients with surgery，reduce postoperative pain，improve patients′care satisfaction，has the value of clinical application. 2016 Vol. 23 (22): 167-169 [Abstract] ( 110 ) HTML (39 KB)  PDF  (0 KB)  ( 23 ) 170 Application of full quality nursing in the radical operation of abdominal perineal resection for rectal cancer FANG Ju-qing Objective To explore the application effect of full quality nursing in the radical operation of abdominal perineal resection for rectal cancer（Miles）.Methods 78 patients with colorectal cancer surgery Miles in our hospital from April 2013 to July 2015 were selected，and were divided into observation group and the control group by using a random number table method，the observation group patients were received quality care throughout the control group patients received usual care.The nursing effect of two groups were compared.Results The total satisfaction rate of the observation group was 94.87%，higher than 66.67%in the control group；SAS score was（40.18±7.25）scores，lower than （53.97±7.69）scores in the control group，the difference was statistically significant（P＜0.05）.The complication rate of observation group was 12.82%，which was significantly lower than 38.46%of control group，the difference was statistically significant（P＜0.05）.Conclusion Full quality care can effectively optimize clinical efficacy in patients with colorectal cancer surgery Miles，reduce the probability of occurrence of complications in patients. 2016 Vol. 23 (22): 170-173 [Abstract] ( 150 ) HTML (41 KB)  PDF  (0 KB)  ( 7 ) 174 Improvement of humanistic nursing on quality of life and satisfaction in patients hospitalized in department of cardiovascular medicine HE Xiao-fang;MO Zhi-fang;ZENG Li-yin Objective To explore the improvement effect of humanistic nursing on quality of life（QOL）and satisfaction in patients hospitalized in department of cardiovascular medicine.Methods From January 2015 to January 2016，144 inpatients hospitalized in our department were selected as research objects.By a random number table，they were evenly divided into observation group and control group.In the control group，conventional nursing was applied，while in the observation group，humanistic nursing was adopted.The QOL in the two groups was compared by GQOL-74，and nursing satisfaction was reflected by questionnaire survey after finishing the intervention.Results There was no difference in GQOL-74 score in the two groups before intervention（P＞0.05）.After intervention，there were statistical differences in cognitive function，mental function，physical performance，and social function with regard to GQOL-74 score，and differences in the observation group were superior to those in the control group with statistical significance（P＜0.05）.The nursing satisfaction in the observation group reached up to 98.61%，much higher than that of control group accounting for 88.89% with a statistical difference（P＜0.05）.Conclusion Humanistic nursing is more suitable for nursing demands in inpatients hospitalized in department of cardiovascular medicine，and comprehensively improves QOL in the aspects of environment，psychology，diet，and safety，as well as nursing satisfaction，which is worthy of clinical promotion and application. 2016 Vol. 23 (22): 174-176 [Abstract] ( 127 ) HTML (39 KB)  PDF  (0 KB)  ( 32 ) 177 Analysis of the effectiveness of high quality nursing in patients with anesthesia for painless gastrointestinal endoscopy YUAN Hai-yan;LI Jian-ping;DUAN Chun-lian Objective To explore the effectiveness of application of high quality nursing in patients with anesthesia for painless gastrointestinal endoscopy.Methods The clinical data of 68 patients who accepted anesthesia for painless gastrointestinal endoscopy in the hospital from September 2013 to October 2015 were analyzed retrospectively.All the patients were divided into two groups randomly with 34 cases in each group.In observation group，the patients were given high quality nursing care；34 cases of control group were given routine nursing care.The effectiveness of nursing of the two groups was compared，and the pre-and post-nursing depression，anxiety and recovery time before and after were observed，and the satisfaction degree and adverse reaction of the two groups were compared.Results The total excellent and good rate of observation group and control group was 94.12%and 73.53%respectively，with statistically significant difference（P＜0.05）；post-nursing SDS score（42.96±3.77），SAS score（45.66±5.29），recovery time（2.27±0.89）min of observation group were significantly less than those of control group，with statistically significant differences（P＜0.05）；the total satisfaction degree and adverse reaction rate of observation group were 91.18%and 17.65%，better than those of control group，with statistical significant difference　（P＜0.05）.Conclusion The application of high quality nursing in patients with anesthesia for painless gastrointestinal endoscopy achieves remarkable effects，which is worthy of clinical application. 2016 Vol. 23 (22): 177-179 [Abstract] ( 123 ) HTML (44 KB)  PDF  (0 KB)  ( 26 ) 180 The risk factors of lumbar disc herniation LIANG Xue-shan Objective To estimate the risk factors of lumbar disc herniation，and to provide scientific evidence for prevention from lumbar disc herniation，and to guide the prevention and nursing of lumbar disc herniation.Methods Patients of lumbar disc herniation randomly from January 2015 to June 2016 hospitalized in our department were selected，there were 200 cases in case group，and 200 cases in control group，totally 400 cases as the research object.With the method of questionnaire research，including family history，body mass index，professional type，single posture daily load duration，lumbar spine.Results The results of univariate analysis showed that family history of lumbar disc herniation cased out 39.5%，while control group was 6.0%，comparing the two groups，the difference was statistically significant（P＜0.01）.There were 72%cases in cases group whose BMI≥24 kg/m2，while there were 48%in control group，comparing the two groups，the difference was statistically significant（P＜0.05）.Cases patients with mental labour，light manual labor，proportion of manual labor，hard physical labor were 28.5%，15.5%，15.0%，41.0%，while the proportion of control group were 30.0%，25.5%，23.5%，21.0%，comparing the two groups，the difference was statistically significant（P＜0.01）.Cases of patients with single posture daily duration more than 4 hours was 56.5%，while the control group is 36.0%，comparing the two groups，the difference was statistically significant（P＜0.05）.Cases lumbar more than 35 kg，the cases group was 36.0%，while the control group was 16.5%，comparing the two groups，the difference was statistically significant　（P＜0.01）.Conclusion Family history，body mass index in patients with lumbar disc herniation patients were higher than in the lumbar intervertebral disc protrusion，professional type，single posture daily duration，lumbar load will increase the risk of lumbar intervertebral disc herniation.Specification，family history，obesity，professional type，single posture daily load duration，lumbar spine are the risk factors of lumbar disc herniation. 2016 Vol. 23 (22): 180-182 [Abstract] ( 134 ) HTML (40 KB)  PDF  (0 KB)  ( 15 ) 183 Psychological and physiological influence of psychological intervention on patients waiting for breast tumor biopsy JIN Feng-zhen;WEN Fu-gang;LIU JunNo.8 Ward，Tumor Hospital of Anshan City，Anshan　114000，China Objective To study the psychological and physiological effects of psychological intervention on breast cancer patients who were waiting for biopsy.Methods Altogether 100 breast cancer patients who underwent pre-surgery breast biopsy in the hospital from January 2013 to December 2015，were randomly selected as the object of research and divided into control group and observation group according to the coin toss method，with 50 cases in each group.Patients in control group were given routine nursing during their waiting for biopsy，and observation group was treated with routine nursing and psychological intervention during their waiting for biopsy.The SAS scores，heart rate and blood pressure were compared between the two groups.Results The SAS score of observation group was significantly lower than that of the control group　（P＜0.05）.The contraction pressure，diastolic blood pressure and heart rate of observation group were not significantly increased　（P＞0.05），30 min after their waiting for biopsy，while the obvious increasing was seen in control group 30 min after their waiting for biopsy　（P＜0.05）.Conclusion The appropriate psychological intervention measures should be taken in patients with breast cancersduring their waiting for biopsy to effectively alleviate the anxiety of patients and regulate the patient′s physiological reaction. 2016 Vol. 23 (22): 183-185 [Abstract] ( 128 ) HTML (39 KB)  PDF  (0 KB)  ( 6 ) 186 The evaluation of nursing intervention on prevention of deep venous thrombosis of lower limb in cesarean section JIANG Hai-ying Objective To study and discuss the clinical value of nursing intervention in prevention of deep venous thrombosis of lower limb in cesarean section.Methods In January 2013 to December 2015，according to the order of treatment，in this stage，100 cases of cesarean section maternal in our hospital were selected，100 cases of pregnant women were divided into the control group and the observation group by taking computer randomization method，each group had 50 cases.The control group was given routine nursing intervention，and the observation group was given comprehensive nursing intervention.After cesarean section，the lower extremity deep vein thrombosis occurrence rate，thigh circumference difference，calf week diameter difference，VAS pain scores and the scores of quality of life were compared between two groups，and before and after the intervention，the maternal anxiety scores of two groups were compared.Results The incidence of deep venous thrombosis after cesarean section in the observation group was 2%，which was significantly lower than that of control group which of 14%（P＜0.05）.Compared with the control group，the thigh difference，leg circumference，VAS pain score of the observation group were significantly smaller（P＜0.05），the socre of life quality in the observation group was significantly higher（P＜0.05）.Compared with before intervention，the maternal anxiety scores of two groups were significantly lower after the intervention（P＜0.05），but after the intervention，the anxiety score of the observation group was significantly lower than that of control group　（P＜0.05）.Conclusion The implementation of comprehensive nursing intervention can effectively reduce the incidence of deep venous thrombosis of lower extremity，alleviate the swelling and pain of lower limbs，and improve the psychological status and life quality of the pregnant women. 2016 Vol. 23 (22): 186-188 [Abstract] ( 137 ) HTML (45 KB)  PDF  (0 KB)  ( 19 ) 189 The application effect of humane care to improve the quality of operating room nursing in patients with gastric cancer WANG Yan-hongSUN Wei Objective To investigate the impact of humane care on the operating room nursing quality in patients with gastric cancer.Methods 40 cases of gastric cancer patients in our hospital from January 2014 to December 2015 were selected as the observation group，and the patients were given radical gastrectomy，and given operating room humane care；Another 40 cases of patients with gastric cancer were given radical gastrectomy at the same time as the control group，and these patients were only accepted operating room routine care.Compared with the two groups of patients before and after nursing in nursing quality score，satisfaction，postoperative anal exhaust time，ambulation time，anxiety and depression level.Results The nursing quality score of observation group was（93.15±2.64），and the control group was（81.43± 2.57），there was statistical significance of the two groups（t=20.119，P=0.000）.The satisfaction of observation group was 97.50%，while the control group was 80.00%，there was statistical significance of the two groups（χ2=6.135，P=0.013）.The postoperative anal exhaust time and ambulation time of observation group were　（1.82±0.31）d and　（5.13±0.91）d，while control group were（3.23±0.24）d and（7.51±1.64）d，there was statistical significance of the two groups（t=22.746，P=0.000；t=8.026，P=0.000）.There was no statistical differences between the anxiety and depression scores before the nursing（P＞0.05）.The scale of SAS and SDS of observation group were（37.56±6.13）and（34.26±3.65），while the control group were （43.18±5.11）and（39.18±4.22），there was statistical significance between the two groups（t=4.454，P=0.000；t=4.863，P= 0.000）.Conclusion Human care can improve the quality of care in patients with gastric cancer，and improve patients′satisfaction of surgery，shorten the postoperative anal exhaust time and ambulation time，also can decrease anxiety and depression level of patients，it is worth to promotion and application in clinical practice. 2016 Vol. 23 (22): 189-191转194 [Abstract] ( 155 ) HTML (44 KB)  PDF  (0 KB)  ( 30 ) 192 Application effect of comprehensive nursing in lung cancer patients provided with paclitaxel and cisplatin chemotherapy WANG Li-jie Objective To explore the application effect of comprehensive nursing in lung cancer patients treated by paclitaxel and cisplatin chemotherapy.Methods From September 2015 to February 2016，46 lung cancer patients admitted into our hospital were selected as research objects.All patients were evenly divided into observation group and control group，23 cases in each group.They were all provided with paclitaxel and cisplatin chemotherapy.In the control group，regular nursing was applied，while in the observation group，comprehensive nursing was adopted.The symptomatic relief and incidence of toxic and side effect in the two groups were compared and observed.Results In the observation group，the symptomatic relief rate after therapy was 95.65%，superior to that of control group accounting for 56.52%　（P＜0.05）. The incidence of toxic and side effect in the observation group was lower than that of control group，with a statistical difference（P＜0.05）.Conclusion In the treatment of lung cancer by paclitaxel and cisplatin chemotherapy，application of nursing intervention can obtain a remarkable effect with high safety. 2016 Vol. 23 (22): 192-194 [Abstract] ( 131 ) HTML (38 KB)  PDF  (0 KB)  ( 19 ) 195 Effect of psychological and pain nursing on anxiety，depression and sleep quality of patients with cervical cancers GUO Ai-qin;NIU Dong Objective To explore the influence of psychological and pain nursing on anxiety and depression and sleep quality of patients with cervical cancers.Methods Altogether 80 cases of advanced cervical cancer patients who were treated in the hospital between January 2013 to June 2015 were divided into two groups（observation group and control group）with 40 cases in each group.Observation group was implemented with mental nursing，pain nursing；while control group with routine nursing.Post-intervention anxiety，depression scores，treatment compliance，nursing satisfaction and post-intervention life and sleep quality were compared between with two groups.Results Post-intervention anxiety and depression scores in observation group were lower than those of control group　（P＜0.05）；treatment compliance，nursing satisfaction，post-intervention life and sleep quality were significantly higher than those of control group（P＜0.01）.Conclusion Combination of application of psychological nursing and pain nursing in patients with advanced cervical cancers can significantly reduce the anxiety and depression of patients，and improve the quality of life and sleep quality. 2016 Vol. 23 (22): 195-封面 [Abstract] ( 134 ) HTML (41 KB)  PDF  (0 KB)  ( 3 )

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