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Quick Search     Adv Search 2017 Vol. 24, No. 1 Published: 2017-01-08   4 Clinicopathologic analysis of 10 cases of renal perivascular epithelioid cell tumors LIN Le；WEI Yong-bao；LI Tao；CHEN Zi-fu；GAO Xiang-xun Objective To explore the clinicopathologic characteristics of renal perivascular epithelioid cell tumors (PEComas).Methods 10 cases of renal PEComas confirmed by pathology from June 2013 to September 2015 in our hospital were followed up,the clinical pathological features were analyzed retrospectively and the treatment plan was summarized.Results In the 10 cases of renal PEComas,male to female ratio was 1∶9,their average age was(50.9±19.5) years old,with a median age of 40.5 years old.All 10 cases were treated by surgical resection.The average time of follow-up was(18.6±8.2)months,with a median follow-up time of 19.5 months.Disease-free survival were found in 7 cases,while two cases survived with tumors and one died.Maximum tumor length was(5.3±2.8)cm,with a median length of 5.1 cm,hemorrhage or necrosis were confirmed in five of them.9 cases were diagnosed as pure renal PEComa.One patient was found accompanied with urothelial cell carcinoma of the renal pelvis.All cases presented positively labeled with HMB45 and/or Melan-A,the average positive ratio of Ki67 was(7.0±6.1)%,with its medium 5.0%.Conclusion As clinical diagnose of renal PEComa is quite difficult,its diagnose mainly relies on pathological findings.Surgical resection is tended to treat this kind of patients.Most of them results well outcomes.For the tumors unable to removed or dealt with conservative treatment,this kind of patients should be closely followed-up. 2017 Vol. 24 (1): 4-8转15 [Abstract] ( 149 ) HTML (43 KB)  PDF  (0 KB)  ( 36 ) 9 Analysis of prostaglandin receptor subtype FP-V2 and drug abortion outcome in early pregnancy MA Chao；FENG Wen-hua；HAN Wei-tian Objective To compare of mRNA expression difference of FP,FP-V1 and FP-V2 in patients with complete abortion and incomplete abortion in early pregnancy deciduas.Methods 50 patients initiatived to require drug abortion termination of normal pregnancy from June 2013 to March 2015 in Liaoning Province Family Planning Research Institute Outpatient were selected as the research objecets,all patients were divided into the complete group(n=30)and the incomplete group(n=20)according to whether complete abortion.The expression difference of FP,FP-V1 and FP-V2 of early pregnancy decidua in the two groups were detected by real-time quantitative PCR.Results The MRNA expression of FP and FP-V2 in decidua in the incomplete group was higher than that in the complete group,with significant difference(P＜0.05).There was no significant difference in the expression of FP-V1 in the two groups(P＞0.05).Conclusion The higher expression of FP-V2 in human early pregnancy decidual may associated with incomplete abortion. 2017 Vol. 24 (1): 9-11转58 [Abstract] ( 155 ) HTML (37 KB)  PDF  (0 KB)  ( 39 ) 12 Research progress of the relationship between inflammatory factor and coronary heart disease SUN Yu-fei；GUO Da-lin The main pathological basis of coronary heart disease(CHD)is atherosclerosis of coronary artery.Local or systemic inflammatory response plays an important role in the occurrence and development of AS and its complications. Exploration of the relationship between inflammatory factors setting as inflammatory response index and CHD is of great significance in early diagnosis,treatment,and prognosis judgment of CHD. 2017 Vol. 24 (1): 12-15 [Abstract] ( 141 ) HTML (40 KB)  PDF  (0 KB)  ( 31 ) 16 The research progress of hyperbaric oxygen treatment of severe acute pancreatitis REN Yi-peng；CHEN Jun-mao；ZHANG Guo-zhi Severe acute pancreatitis(SAP)is a kind of acute abdomen disease with danger disease and high rate of mortality.Pathogenesis of SAP is a complex and multiple factors involved process.At present,the definitive pathogenesis is not fully understood.In recent years,a large number of studies have shown that hyperbaric oxygen(HBO)plays an important role in the treament of SAP.The influence of HBO treatment on SAP is reviewed in this paper. 2017 Vol. 24 (1): 16-18 [Abstract] ( 147 ) HTML (34 KB)  PDF  (0 KB)  ( 33 ) 19 The significance of dynamic monitoring of blood lactic acid in the treatment of multiple organ dysfunction syndrome LUAN Jing；WANG Yan-zhen；PU Yong-peng；CHEN Wei；HAN Xu；BAN Li-hong Objective To investigate the significance of dynamic monitoring of blood lactic acid(LAC)in the treatment of multiple organ dysfunction syndrome(MODS).Methods 63 patients with MODS in the Intensive Care Unit of the First People′s Hospital of Lanzhou City treated from January 2015 to October 2016 were divided into experimental group and control group according to the monitoring of LAC or not.The supplementary liquid and vasoactive drugs were adjusted and the treatment was upgraded according to blood LAC level,CVP,ScvO2,MAP and urine volume on 32 cases in experimental group,but according to CVP,ScvO2,MAP and urine volume on 31 cases in control group only.The GCS, PaO2/FiO2,PAHR,bilirubin,Cr,PLT of two groups were recorded and scored for MODS severity on admission,24 hours, 48 hours and 72 hours after admission.WBC,PCT and APACHEⅡwere compared between two groups were on admission and 72 hours after admission.And MODS severity score,mechanical ventilation time,duration in intensive care unit and mortality were compared.Results WBC,PCT of the experimental group was significantly lower than that of the control group 72 hours after admission,and the difference was statistically significant(P＜0.01);APACHE,MODS score of the experimental group was significantly lower than that of the control group,and the difference was statistically significant (P＜0.01);mechanical ventilation time,duration in intensive care unit of the experimental group was significantly shorter than that of the control group,and the difference was statistically significant(P＜0.01).Conclusion Dynamic monitoring of LAC and lactate clearance rate(LCR)has important guiding significance in the treatment of MODS,the index is stable,reliable and can shorten mechanical ventilation time and duration in intensive care unit. 2017 Vol. 24 (1): 19-22 [Abstract] ( 171 ) HTML (37 KB)  PDF  (0 KB)  ( 39 ) 23 Effect of transumbilical single-port laparoscopic appendectomy for chronic appendicitis WANG Ying-fei；LIN Yong-li；ZHU Bing Objective To explore the clinical effect of transumbilical single-port laparoscopic appendectomy in the treatment of chronic appendicitis.Methods From January 2012 to December 2015,140 cases of chronic appendicitis patients in our hospital were selected as study subjects and divided into two groups by random number table method,each group had 70 cases.Patients in control group were given routine appendectomy,and patients in observation group were treated with transumbilical single-port laparoscopic appendectomy.Operation time,intraoperative blood loss,anal exhaust recovery time,hospital stay,postoperative pain score,postoperative complication rate were compared between two groups. Results Operation time of two groups were compared,the difference was not statistically significant(P＞0.05),but intraoperative blood loss in the observation group was significantly less than that in the control group(P＜0.01),anal exhaust recovery time and hospital stay was significantly shortened(P＜0.01),and postoperative pain scores was significantly lower(P＜0.01).Postoperative complication rate of the observation group was 2.86%,significantly lower 11.43%of the control group(P＜0.05).Conclusion Transumbilical single-port laparoscopic appendectomy in the treatment of chronic appendicitis can effectively reduce trauma caused by surgery to patients,reduce postoperative complications,promote postoperative recovery. 2017 Vol. 24 (1): 23-25 [Abstract] ( 147 ) HTML (32 KB)  PDF  (0 KB)  ( 39 ) 26 Study of hemodynamics and pulmonary function in patients with chronic obstructive pulmonary disease associated pulmonary hypertension HUANG Xiao-juan；TANG Yan；QIN Hua-yuan Objective To analyze change of hemodynamics and pulmonary function in patients with chronic obstructive pulmonary disease(COPD)associated pulmonary hypertension(PH),and to provide scientific basis for the treatment of COPD.Methods 92 patients with COPD associated PH in our hospital from March 2014 to July 2016 were selected as research object and divided into severe COPD associated PH group(severe group)and non severe COPD associated PH group(non severe group)according to the type of disease,46 cases in each group.Changes of hemodynamic parameters (mean pulmonary arterial pressure,pulmonary wedge pressure,pulmonary vascular resistance,right atrial pressure,cardiac index)and parameters of pulmonary function(peak velocity,maximal ventilatory volume,residual volume,maximal midexpiratory flow,airway resistance,deep breathing volume)were analyzed in two groups.Results Pulmonary artery average pressure,pulmonary wedge pressure,pulmonary vascular resistance,right atrial pressure,cardiac index was statistically significant(P＜0.05)between two group,hypoxemia in the severe group was more significant,hypoxia degree of COPD associated PH was more serious,impairment degree of hemodynamic was more significant.Peak velocity,maximal ventilatory volume,residual volume,maximal midexpiratory flow,airway resistance,deep breathing volume pulmonary function index was not statistically significant between two groups(P＞0.05).Conclusion Patients with COPD associated PH have hemodynamic impairment,hypoxemia in patients with severe COPD associated PH is significant,but the hypoxemia in patients with severe COPD associated PH is significant,and may be related to pulmonary vascular factors. 2017 Vol. 24 (1): 26-28 [Abstract] ( 152 ) HTML (32 KB)  PDF  (0 KB)  ( 40 ) 29 Clinical analysis of 52 cases acute exacerbation of chronic obstructive pulmonary disease complicated by typeⅡrespiratory failure treated by non-invasive ventilator LIU Yun Objective To explore the clinical effect of bi-level positive airway pressure（BiPAP）with non-invasive ventilator in treating acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated by typeⅡrespiratory failure.Methods The clinical data of 52 cases of AECOPD patients in our hospital from January 2013 to June 2016 were selected to conduct the research,they were devided into two groups,patients in observation group were treated with non-invasive ventilator,with routine treatment in control group.Blood gas analysis,respiratory rate and heart rate before ana after treatment between two groups were compared.Results After treatment,artery blood pH and arterial partial pressure of oxygen was significantly higher,arterial partial pressure of carbon dioxide significantly decreased,and more significantly changes in the observation group,there was significant difference(P＜0.05).After treatment,respiratory rate,heart tate significantly decreased,and more significantly changes in the observation group,there was significant difference(P＜0.05).Conclusion On the basis of conventional treatment,non-invasive ventilator treatment for elderly patients with AECOPD complicated by typeⅡrespiratory failure has a significant clinical effect,and it is convenient, practical,worthy of clinical application. 2017 Vol. 24 (1): 29-31 [Abstract] ( 161 ) HTML (36 KB)  PDF  (0 KB)  ( 43 ) 32 Clinical application value quadriceps functional exercising in the pulmonary rehabilitation of patients with COPD CHEN Hua；GAO Xiao-ming；SONG Hui-qin Objective To explore clinical application effect of quadriceps functional exercising on the pulmonary rehabilitation of patients with chronic obstructive pulmonary disease(COPD).Methods clinical data of 100 patients with COPD in our hospital from January 2015 to August 2016 were analyzed,which were divided into conventional therapy group of 50 cases and quadriceps functional exercising group of 50 cases by different rehabilitation measures.PaO2,Pa-CO2,6 min walk test,FEV1,FEV1/FVC,FEV1%Pred of two groups before and after treatment were observed.Results PaO2, PaCO2,6 min walk test,FEV1,FEV1/FVC,FEV1%Pred before treatment between two groups had no difference(P＞0.05). PaO2,PaCO2,6 min walk test,FEV1,FEV1/FVC,FEV1%Pred after treatment in the quadriceps functional exercising group was better than that in the conventional therapy group,PaO2,PaCO2,6 min walk test,FEV1,FEV1/FVC,FEV1%Pred after treatment was better than that before treatment in two groups,and the differences were statistical significance(all P＜0.05).Conclusion The application of quadriceps functional exercising in the pulmonary rehabilitation of patients with COPD could improve lung function of patients,it is worth to be used. 2017 Vol. 24 (1): 32-34 [Abstract] ( 154 ) HTML (36 KB)  PDF  (0 KB)  ( 36 ) 35 Effect of positive end expiratory pressure combined with prone ventilation on oxygenation and circulation in patients with ARDS LIU Yun-ge Objective To study effect of positive end expiratory pressure(PEEP)combined with prone ventilation on oxygenation and circulation in patients with acute respiratory distress syndrome(ARDS).Methods From June 2013 to September 2014,a total of 80 patients with ARDS in our hospital were taken as research objects and divided into control group(40 cases)and observation group(40 cases)by random number table method.Both groups were treated with PEEP,patients in the observation group accepted additional prone ventilation.Oxygenation indexes,intensive care unit (ICU)stay time,mechanical ventilation time,mean arterial pressure(MAP)and heart rate(HR)of two groups were compared and analyzed,and 28 d mortality rates and complication rates of two groups were recorded.Results Oxygenation index of the observation group was 162.14±2.87,which was significantly higher than 135.76±1.89 of the control group (P＜0.05);ICU stay time and mechanical ventilation time of the observation group was significantly shorter than that of the control group(P＜0.05).There were no significant differences in each group or between two groups in MAP and HR before and after treatment(P＞0.05).28 d mortality rate of the observation group was 2.50%,which was significantly lower than 17.50%of the control group(P＜0.05);complication rates of two groups was respectively 7.50%and 5.00%,and there was no significant difference between two groups(P＞0.05).Conclusion PEEP combined with prone ventilation has the advantage of less effect on blood circulation and no obvious increase of serious complications,can effectively improve oxygenation and prognosis for ARDS patients.Thus,it is worthy of clinical application and promotion 2017 Vol. 24 (1): 35-37 [Abstract] ( 165 ) HTML (33 KB)  PDF  (0 KB)  ( 35 ) 38 Application research on clinical pathway in perioperative period of total knee arthroplasty in prefecture-level three top hospital YANG Jian-qi；OUYANG Ju-xiang；GONG Jin-chun；ZHANG Xi-shun；LIN Miao-jun Objective To explore the application effect of clinical pathway in total knee arthroplasty in prefecture-level three top hospital.Methods Clinical date of 733 patients with severe osteoarthritis who received total knee arthroplasty operation in the First People′s Hospital of Foshan City from March 2008 to March 2016 were analyzed retrospectively and divided into clinical pathway group(n=392,according to the former ministry of Health in 2009 edition of severe knee osteoarthritis clinical pathway treatment intervention)and traditional medicine group(n=341,who were given previous clinical procedures)according whether or not to accept clinical pathway.Hospitalization days before operation, hospitalization days after operation,total hospitalization days,total hospitalization costs,treatment costs,drug costs,inspection costs,cost of materials,incidences of complications,KSS knee function score,VAS knee pain score,patient satisfaction and other indicators were assessed and analysed.Results There was significant difference(P＜0.05)between two groups among hospitalization days after operation(t=2.637,P=0.020),total hospitalization days(t=3.688,P=0.000),postoperative complication rate(χ2=9.694,P=0.002),hospitalization days before operation(t=2.879,P=0.007),postoperative KSS score of knee joint(t=7.331,P=0.000),cost of materials(t=2.727,P=0.010),patient satisfaction(t=6.047,P=0.014).There was no significant difference between two groups in total hospitalization costs,treatment costs,drug costs,othercosts and postoperative pain scores(P＞0.05).Conclusion The application of clinical pathway in total knee arthroplasty in prefecture-level three top hospital can regulate clinic medical treatment,reduce hospitalization days,reduce complications,improve treatment result and improve patient satisfaction,but can not control hospitalization costs obviously in prefecture-level three top hospital at this stage. 2017 Vol. 24 (1): 38-42 [Abstract] ( 149 ) HTML (45 KB)  PDF  (0 KB)  ( 33 ) 43 Clinical curative effect observation of low dose Prednisone with progressive therapy on senile ocular myasthenia gravis WANG Ai；ZHANG Fu-qiu；XIE Li-shi Objective To study the clinical effect of using low doses of Prednisone with progressive therapy in the treatment of ocular myasthenia gravis in the elderly.Methods 179 elderly patients with ocular myasthenia gravis in our hospital from October 2006 to January 2015 were selected and divided into observation group(n=90)and control group(n= 89),In the observation group,the drug was administered by a low dose escalation,and in the control group was given routine oral administration.All patients were followed up for more than one year.Results Total effective rate in the observation group was 92.2%,with 77.5%in the control group,and the difference was statistically significant(P＜0.05).Recurrence rate in the observation group was 27.8%,and that of the control group was 68.5%,and the difference was statistically significant(P＜0.05).Conclusion Using low doses of incremental dosing method can improve treatment effect of elderly patients with ocular myasthenia gravis,shorten time and dose of hormone,but also can effectively reduce the incidence of adverse drug reaction. 2017 Vol. 24 (1): 43-45 [Abstract] ( 156 ) HTML (31 KB)  PDF  (0 KB)  ( 30 ) 46 Effect of compound Bismuth Magnesium quadruple therapy in the treatment of Hp-related peptic ulcer CHEN Ji-yun；HUANG Pei-ning；LUO Xia Objective To observe clinical effect compound Bismuth Magnesium Granules combined with Esomeprazole, Amoxicillin and Clarithromycin in the treatment of Hp-related peptic ulcer.Methods 172 patients with Hp infectionpositive peptic ulcer disease in People′s Hospital of Baise City from June 2014 to May 2016 were randomly divided into 3 groups,60 cases in standard triple therapy group,56 cases in compound Bismuth Magnesium quadruple therapy group,56 cases in colloidal bismuth pectin quadruple therapy group.Patients in the standard triple therapy group were given Esomeprazole,Clarithromycin,Amoxicillin for 10 days,and then with oral Esomeprazole for another 28 days.The other two groups was added compound Bismuth Magnesium Granules and colloidal bismuth pectin for 10 days on the basis of the standard triple therapy treatment respectively.The remission of pain symptoms,ulcer healing,Hp eradication rates,ADR of three groups were observed.Results Hp eradication rate(94.6%,53/56),remission rate of pain symptoms (85.7%,48/56),ulcer healing rate(89.3%,50/56)of compound Bismuth Magnesium quadruple therapy group was significantly better than that of standard triple therapy group(68.3%,41/60;43.3%,26/60;70.0%42/60),ADR rate(14.3,8/56) was significantly lower than(31.7%,19/60)of standard triple therapy group(the former two items were P＜0.05,the latter two items were P＜0.01).There was no statistical significance between four items results of colloidal bismuth pectin quadruple therapy group(83.9%,47/56;58.9%,33/56;83.9%,47/56;19.6%,11/56)and standard triple therapy group(P＞0.05),while remission rate of pain symptoms had statistical significance between compound Bismuth Magnesium quadruple therapy group and colloidal bismuth pectin quadruple therapy group(P＜0.01).Conclusion Compound Bismuth Magnesium quadruple therapy in the treatment of Hp-related peptic ulcer has better effect in remission of pain symptoms, and significant effects on ulcer healing and Hp eradication.What′s more,it does not add ADR.So it has a certain advantage and a better safety in the treatment of peptic ulcer. 2017 Vol. 24 (1): 46-48 [Abstract] ( 144 ) HTML (32 KB)  PDF  (0 KB)  ( 43 ) 49 Clinical effect of sequential mechanical ventilation on severe pneumonia complicated with respiratory failure ZENG Wei-jian Objective To explore clinical effect of sequential mechanical ventilation on severe pneumonia complicated with respiratory failure.Methods Clinical data of 224 patients with severe pneumonia complicated with failure respiration in our hospital from December 2014 to December 2015 were analyzed,which was divided into two groups by different treatment methods,control group(invasive mechanical ventilation treatment)104 cases and observation group(sequential mechanical ventilation treatment)120 cases.Invasive ventilation time,total mechanical ventilation time,length of hospital stay(LOS),incidence rate and mortality of respiratory associated pneumonia,HR,RR,PaCO2,PaO2when in group and PIC were observed.Results Invasive ventilation time,total mechanical ventilation time,LOS,incidence rate and mortality of respiratory associated pneumonia in the observation group was lower than that in the control group,and the difference was statistical significance(P＜0.05).HR,RR,PaCO2,PaO2between two groups when in group had no difference (P＞0.05).PaO2PaCO2between two groups when PIC had no difference(P＞0.05);HR,RR in the observation group was lower than that in the control group when PIC,and the difference was statistically significant(P＜0.05).HR,RR,PaCO2in two groups when PIC was lower than that when in group,and the difference was statistical significance(P＜0.05);there was no significant difference in two groups in PaO2when PIC compared with when in group(P＞0.05).Conclusion Sequential mechanical ventilation in the treatment of patients with severe pneumonia compared with failure respiration can shorten ventilation time and improve obviously hemodynamics,it is worth to be used. 2017 Vol. 24 (1): 49-51 [Abstract] ( 151 ) HTML (33 KB)  PDF  (0 KB)  ( 37 ) 52 Advantages and disadvantages analysis of breast approach endoscopic thyroidectomy and traditional operation in treating thyroid disease LI Li-nong；ZHAO Han-peng；ZHU Jin-teng；MA Teng-fei；SHEN Yi-jun；LIN Jie-xian Objective To explore the effect difference of breast approach endoscopic thyroidectomy and traditional operation in treating thyroid disease.Methods 49 patients who conducted breast approach endoscopic thyroidectomy in our hospital from March 2012 to December 2015 were selected as experimental group,35 patients who conducted traditional operation at the same term were selected as control group.Operation related data,postoperative complications and patients′satisfaction to incision in two groups were observed.Results Intraoperative blood loss in the experimental group and the control group was respectively(15.98±8.80),(25.01±7.54)ml,and the difference was statistical significance(P＜0.01);24 h indueed flow volume after operation in the experimental group was obvious less than that in the control group(P＜0.01);length of hospital stay was obviously shorter than that in the control group(P＜0.01),but average hospitalization expenses in the experimental group was obviously more than that in the control group(P＜0.01).Incidence rate of complications in the experimental group was 24.49%,which had no obvious difference with 28.57%in the control group(P＞0.05).Patients′satisfaction to incision in the experimental group and the control group was respectively 97.96%(48/49)and 14.29%(5/35)(χ2=61.388,P＜0.05).Conclusion Breast approach endoscopic thyroidectomy has less trauma on patients,shorter length of hospital stay,faster postoperative recovery and with better incision cosmetic effect. For patients with economic conditions permit,it can be recommended as the best choice. 2017 Vol. 24 (1): 52-54 [Abstract] ( 135 ) HTML (31 KB)  PDF  (0 KB)  ( 40 ) 55 Clinical study of Deanxit combined with Pantoprazole in the treatment of abdominal pain syndrome combined with anxiety and depression XUE Jian-bo；TONG Jian-jun；MA Li；XU Tao Objective To explore efficacy of Deanxit(Melitracen and flupentixol)combined with Pantoprazole in the treatment of epigastric pain syndrome(EPS)combined with anxiety and depression.Methods 172 patients with EPS combined with anxiety and depression in our hospital from March 2012 to July 2016 were randomly divided into two groups by random digital distribution method,patients in treatment group(n=86)received Deanxit plus Pantoprazole orally,and control group(n=86)received Pantoprazole orally.The course of treatment was 4 weeks.The symptoms,such as repeated epigastric burning and epigastric pain were evaluated.Results After treatment for 4 weeks,scores of HADs in treatment group was lower than that before treatment(P＜0.01),however,there was no difference in control group(P＞0.05).After treatment,the difference was statistically significant in HADs score between two groups(P＜0.01);EPS symptom score in the treatment group was significantly greater than that in the control group(P＜0.01).There was a significant difference in total effectiveness rate between two groups(83.7%vs.46.5%,P＜0.01).After treatment,onset time of the treatment group was(4.2±0.8)d,with(5.9±1.5)d in the control group,and the difference was statistically significant (P＜0.01).Conclusion Deanxit has a satisfactory efficacy and slight adverse reactions in the treatment of epigastric pain syndrome with symptoms of anxiety and depression,which has an important clinical significance. 2017 Vol. 24 (1): 55-58 [Abstract] ( 157 ) HTML (39 KB)  PDF  (0 KB)  ( 31 ) 59 Clinical study of different dose of Rosuvastatin for elderly patients with coronary artery borderline lesion YUAN Shan-bin；WU Yong-hua；GAN Guang-ping Objective To explore the clinical effect of different dose of Rosuvastatin for elderly patients with coronary artery borderline lesion.Methods 220 elderly patients with coronary artery borderline lesion treated by our hospital from May 2014 to May 2015 were selected and they were randomly divided into the two groups.The observation group (111 patients)was treated by high-dose of Rosuvastatin,while the control group(109 patients)was treated by small dose of Rosuvastatin.Clinical symptom remission rate,incidence rate of adverse reactions and IMT of carotid and TG,HDL-C, hs-CRP,LDL-C,TC level in patients between two groups was compared respectively.Results IMT value[(1.36±0.05)cm], incidence rate of adverse reactions(0.90%),and TG value[(0.32±0.05)mmol/L],HDL-C value[(1.89±1.85)mmol/L], hs-CRP value[(9.06±1.42)μg/L],LDL-C value[(0.30±0.08)mmol/L]and TC value[(1.78±0.32)mmol/L]after treatment in observation group was obviously better than that of control group[(2.36±0.98)cm,29.36%,(1.54±0.65)mmol/L, (1.02±0.69)mmol/L,(13.47±4.25)μg/L,(1.36±1.47)mmol/L,(1.57±0.04)mmol/L]respectively(P＜0.05).Conclusion High dose of Rosuvastatin for elderly patients with coronary artery borderline lesion is more significant. 2017 Vol. 24 (1): 59-61 [Abstract] ( 145 ) HTML (31 KB)  PDF  (0 KB)  ( 30 ) 62 Effect of Trimetazidine on myocardial ischemia in patients with coronary heart disease complicated with stable exertional angina pectoris CHEN Lian-di Objective To explore the effect of Trimetazidine on myocardial ischemia in patients with coronary heart disease(CHD)complicated with stable exertional angina pectoris.Methods 90 patients with CHD complicated with stable exertional angina pectoris treated by our hospital from May 2014 to April 2016 were selected as research objects.They were evenly divided into two groups by computer randomization with 45 cases in each group.In control group,conventional drug therapy was used,while in research group,on the basis of the conventional drug therapy,Trimetazidine was added. The motion testing outcome,frequency of angina pectoris attack in one week,heart rate,heart rate-systolic blood pressure product,and therapeutic effect were compared between two groups.Results The motion testing outcome of the observa tion group∶ST segment lasting 1 mm[(405.39±52.16)s],attack time of exercise-induced angina pectoris[(453.26±59.24)s], the exercise-lasting time[(681.26±53.46)s]was longer than those of control group[(314.26±52.16)s,(351.34±50.31)s, (505.34±41.36)s](P＜0.05).The frequency of angina pectoris attack in one week[(1.34±0.28)times]in the observation group was obviously fewer than that of control group[(4.56±1.25)times](P＜0.05).There was no statistical difference in heart rate and heart rate-systolic blood pressure product between two groups(P＞0.05).The total effective rate(95.56%) in observation group was higher than that of the control group(68.89%)(P＜0.05).Conclusion Trimetazidine is an effective drug in the treatment of CHD complicated with stable exertional angina pectoris,and can effectively prevent or improve the symptoms of myocardial ischemia in patients. 2017 Vol. 24 (1): 62-64 [Abstract] ( 149 ) HTML (33 KB)  PDF  (0 KB)  ( 36 ) 65 Effect of Irbesartan on plasma myeloperoxidase and blood uric acid in patients with unstable angina pectoris XIE Ying-wei；LI Ru-cheng；CHEN Jian-hua Objective To explore the effect of Irbesartan on myeloperoxidase(MPO)and blood uric acid(BUA)in patients with unstable angina pectoris(UAP).Methods From April 2015 to March 2016,86 patients with UAP admitted to our hospital and cooperative hospital were evenly divided into routine treatment group and Irbesartan treatment group in random.Patients in both groups were provided with coronary dilatation,anticoagulation and lipid regulation.In the Irbesartan treatment group,on the basis of the routine treatment group,oral administration of irbesartan(150 mg each time, once per day).One course of treatment lasted for 8 weeks.The plasma MPO level was tested by ABC-Elisa and BUA level was measured by fully automatic biochemical analyser.Results Compared with before treatment,plasma MPO and BUA level was greatly decreased in the two groups(P＜0.05).After treatment,plasma MPO and BUA level in the Irbesartan treatment group were greatly lower than those in the routine treatment group(P＜0.05).Conclusion Irbesartan has significant inhibitory effect on plasma MPO and BUA level in patients with UAP. 2017 Vol. 24 (1): 65-67 [Abstract] ( 146 ) HTML (33 KB)  PDF  (0 KB)  ( 30 ) 68 Role of PAF and CRP levelincardio-cerebral-vascular endothelial injury and its disease development in patients with primary hypertension XIE Bai-hua；GAO Sheng-fu；HE Yan-hong；LU Ye-rong；WU Ai-hua Objective To explore the role of platelet activating factor(PAF)and C reactive protein(CRP)level in cardio-cerebral-vascular endothelial injury and its disease development in patients with primary hypertension.Methods From January 2015 to January 2016,58 patients with primary hypertension were collected in our hospital were the experimental group,while 50 healthy participants from physical examinationwere collected and classified into the control group.The indexes of PAF and CRP in the two groups were tested.Results ThePAF levelin the experimental group and the control group was(155.80±35.81)ng/ml and(80.94±20.77)ng/ml respectively,and the CRP level was(9.87±3.57)mg/L and(2.11±0.94)mg/L,and there was a statistical difference of PAF and CRP level(P＜0.05).The PAF and CRPlevel in gender were not displayed obvious difference(P＞0.05).PAF and CRP level in patients aged over 50 years old were both higher than those in patients less than 50 years old(P＜0.05).Along with the increase of the course of diseasein patients, PAF levelwas greatly increased(P＜0.05),while CRP level was not in obvious increase(P＞0.05).PAF had a positive correlation with age,as well as CRP.PAF and CRP had positive correlations with PAR,WBC,PLT,FIB,CHOL and SBP.Conclusion PAF and CRP level have a higher value on monitoring cardio-cerebral-vascular endothelial injuryand disease changein patientswith primary hypertension,which is suitable for promotion. 2017 Vol. 24 (1): 68-70 [Abstract] ( 150 ) HTML (28 KB)  PDF  (0 KB)  ( 35 ) 71 Multiple correlation factor analysis of femoral head necrosis in young and middle-aged patients with femoral neck fractures after operation YANG Wei-zhen；ZHANG Jian-feng；LI Wen-qin；ZHANG Li-feng Objective To investigate the factors related to femoral head necrosis after closed reduction and cannulated screw in the treatment of femoral neck fractures in young and middle-aged patients.Methods 256 young and middleaged patients with femoral neck fracture in our hospital from February 2008 to December 2012 were retrospectively analyzed,All patients were treated with closed reduction and internal fixation with cannulated screws.The factors associated with the femoral head necrosis were analyzed,including age,gender,fracture classification,whether the cyst decompression,operatioval interval time,quality of reduction,postoperative hip joint Harris score,time of full-weight-loading and whether or not to remove the internal fixational.Results All cases were followed up for an average of(32.07±14.69) months.31 cases occurred femoral head necrosis,which accounted for 12.10%.Age,fracture type,operation interval,quality of reduction,postoperative Harris score,total weight-bearing time and whether or not to remove the internal fixationl were found correlated to outcome of a femoral neck fracture.Conclusion Quality of reduction,operational interval time, time of full-weight-loading and f whether or not to remove the internal fixationl are found to have the most significant influence on femoral head necrosis after femoral neck fracture with internal fixation in young and middle-aged patients. 2017 Vol. 24 (1): 71-75 [Abstract] ( 168 ) HTML (44 KB)  PDF  (0 KB)  ( 33 ) 76 Effect of arthroscopic assisted treatment of adolescents habitual patellar dislocation complicated with patellar cartilage fracture WANG Shuan-chi；TAO Xiao-bing；WANG Fang-fang Objective To explore the effect of arthroscopic assisted treatment of adolescents habitual patellar dislocation complicated with patellar cartilage fracture by using the methods of absorbable screw,combined lateral patella retinaculum release and medial retinaculum tightening suture.Methods A total of 7 young patients with habitual patellar dislocation complicated with patellar cartilage fracture from February 2008 to May 2014 were selected as the research objects.All patients were treated with surgical treatment,included arthroscopic exploration,release of lateral patella retinaculum,reduction and internal fixation for patella cartilage with absorbable screw,medial patellar retinaculum reefing.Plaster immobilization were needed for 3 weeks Postoperative.All patients were began functional training.3 months after operation,weight-bearing activities were began if the X-ray or CT showed patella cartilage healing.HSS score was used to evaluate knee function and evaluate patellar dislocation.Results All 7 patients achieved fracture healing without patellar dislocation after operation for 6 months.According to HSS evaluation,6 cases were excellent,one case was good. Conclusion The effect of the combined operation method of arthroscopic exploration,release of lateral patella retinaculum,reduction and internal fixation for patella cartilage with absorbable screw,medial patellar retinaculum reefing in the treatment of adolescents habitual patellar dislocation complicated with patellar cartilage fracture is satisfactory. 2017 Vol. 24 (1): 76-79 [Abstract] ( 148 ) HTML (39 KB)  PDF  (0 KB)  ( 28 ) 80 Efficacy analysis of medium and long term of percutaneous transforaminal endoscopic discectomy in the treatment of calcified lumbar disc herniation FANG Shi-bing；ZHONG Hong-fa；CHEN Rong-chun Objective To explore the medium and long term efficacy of percutaneous transforaminal endoscopic discectomy(PTED)in the treatment of calcified lumbar disc herniation(CLDH).Methods 35 patients with CLDH in our hospital from September 2012 to September 2015 were selected and divided into the routine group(18 cases)and the PTED group(17 cases)according to the different treatment methods,and were treated with traditional open window discectomy and PTED,respectively.The medium and longterm efficacy of the two groups was compared.Results The incision length,postoperative bed time and length of stay of the PTED group was shorter than that of the routine group,the intraoperative bleeding volume of the PTED group was less than that of the routine group,with significant difference(P＜0.05).The VAS scores and ODI index in the PTED group at 6 months and 1 year after operation was lower than that in the routine group,with significant difference(P＜0.05).There was no significant difference in the excellent and good rate of Nab Mac between the two groups(P＞0.05).Conclusion For the treatment of CLDH,PTED and traditional open window discectomy has a similar medium and long term efficacy,and PTED has the advantages of small trauma and fast recovery after surgery,it is worth recommending. 2017 Vol. 24 (1): 80-82转85 [Abstract] ( 150 ) HTML (36 KB)  PDF  (0 KB)  ( 36 ) 83 Clinical effect observation of two pathways for internal fixation in the treatment of thoracolumbar burst fracture combining with spinal cord injury ZHU Jin-ming Objective To explore the clinical effect of two anterior-posterior internal fixations in the treatment of thoracolumbar burst fracture combining with spinal cord injury(SCI).Methods 71 patients who were suffered from thoracolumbar burst fracture combining with SCI from February 2014 to October 2015 in our hospital were selected and divided into group A(n=35)and group B(n=36)according to a random number table method.Group A was treated with posterior internal fixation,group B was treated with anterior internal fixation.The clinical therapeutic effect in both groups was compared.Results There was no significant difference in the length of operation,amount of intraoperative bleeding or healing time of plant bone mass in the two groups(P＞0.05).There was no significant difference in the height of anterior margin,posterior margin or kyphotic Cobb angle in the injured vertebra between group A and group B after surgery for 1 week(P＞0.05).The incidence rate of complications in group A was 8.6%,while the incidence rate was 5.6%in group B,there was no significant difference in the incidence rate of complication between the two groups(P＞0.05).Conclusion In the treatment of thoracolumbar burst fracture combining with SCI,the therapeutic effect of the anterior/posterior is similar.An appropriate surgical method is selected according to comprehensive considerations of individual difference,disease conditions,and hospital qualification in clinic. 2017 Vol. 24 (1): 83-85 [Abstract] ( 127 ) HTML (30 KB)  PDF  (0 KB)  ( 33 ) 86 Effect observation of conservative therapy on acute central spinal cord syndrome caused by low energy neck injury in the elderly WANG Mei-lin Objective To explore the therapeutic effect of conservative therapy on acute central spinal cord syndrome (ACCS)caused by low energy neck injury in the elderly.Methods 67 elderly patients with ACCS in our hospital from January 2012 to October 2015 were selected and divided into the conservative group(35 cases)and the operation group (32 cases)according to the different treatment methods.the conservative group was treated with conservative treatment, the operation group was given surgical treatment.The treatment effect of the two groups was compared.Results The score of ASIA and SCIM-Ⅲafter 1 year of follow-up in the two groups were higher than that before treatment,with significant difference(P＜0.05).There was no significant difference in the score of ASIA and SCIM-Ⅲafter 1 year of follow-up between the two groups(P＞0.05).There was no significant difference in the total incidence rate of complications between the two groups(25.71%vs.37.50%,P＞0.05).Conclusion The conservative treatment and surgery have similar clinical effects for the elderly ACCS patients with low energy neck injury. 2017 Vol. 24 (1): 86-88 [Abstract] ( 100 ) HTML (30 KB)  PDF  (0 KB)  ( 32 ) 89 Significance of circumcision in the treatment and prevention of urinary tract infection in boys MENG Na-na；CHEN Shen-quan；SU Li-huan Objective To explore the significance of circumcision in the treatment of urinary tract infection（UTI）in boys.Methods Form January 2014 to January 2016 in outpatient department of our hospital and hospitalization boys with urinary tract infection complicated with foreskin dysplasia were selected as the study objects,acording to the will of children and their parents,45 children with the consent of circumcision were selected as the experiment group,and 45 children without interesting of circumcision were selected as the control group.Experiment group was given the antibiotic therapy and circumcision implementation while the control group was treated with antibiotics alone.The urine routine and cleaning middle urine cultivation were carried among patients of the two groups 1，2 weeks and 6 months after treatment，the data were statistically analyzed.Results The count of white blood cell and colony in two groups was significantly decreased 1,2 weeks after treatment，clinical symptoms disappeared 2 weeks after treatment,the treatment time was（8.0±1.7），（9.0±2.7）d in the experiment group and control group respectively,there was no significant difference between the two groups（P＞0.05）.6 months after treatment，the positive rate of white blood cell count in the experiment group was 4.4%（2/45），and the control group was 24.4%（11/45）;the positive rate of urine culture positive rate in the experiment group was 2.2%（1/45），and the control group was 15.5%（7/45），the differences between the two groups were statistically significant（P＜0.05）.Conclusion Circumcision can reduce the incidence of UTI in boys to a certain extent，especially for boys with foreskin dysplasia，can effectively prevent and control the recurrence of UTI in boys. 2017 Vol. 24 (1): 89-91 [Abstract] ( 118 ) HTML (31 KB)  PDF  (0 KB)  ( 30 ) 92 Effect of audio-frequency medication through Zigong acupoint in the treatment of infertility due to fallopian tube obstruction and distal tube adhesion HU Shen-bi Objective To explore the effect of audio-frequency medication through Zigong acupoint(EX-CA1)on treating infertility due to fallopian tube obstruction and distal tube adhesion.Methods From November 2008 to November 2015,90 patients in our hospital were selected and evenly divided into control group,observation group and treatment group.In the control group,only audio-frequency electrical therapy was used.In the observation group,audio-frequency medication therapy was adopted.In the treatment group,audio-frequency medication through EX-CA1 was applied.The therapeutic effect in each group was compared.Results In the treatment group,the pregnancy rate was significantly higher than that of the control group and observation group(50.0%,30.0%and 33.3%,all P＜0.05),the differences were statistically significant;the abortion rate was greatly lower than that in the control group and observation groups(10.0%, 40.0%and 20.0%,all P＜0.05),the differences were statistically significant.The cure rate in the treatment group was remarkably higher than that in the control group and observation group(60.0%,46.7%and 50.0%,all P＜0.05),the differences were statistically significant.The ineffective rate was 10.0%in the treatment group,much lower than that in the control and observation group(10.0%,20.0%and 20.0%),the differences were statistically significant(all P＜0.05).Conclusion Application of audio-frequency medication through EX-CA1 obtains a great effect on treating infertility due to fallopian tube obstruction and distal tube adhesion.Compared with only audio-frequency medication,there are obvious difference in effect,symptomatic improvement,pregnancy rate,and fertility rate. 2017 Vol. 24 (1): 92-94 [Abstract] ( 127 ) HTML (34 KB)  PDF  (0 KB)  ( 39 ) 95 Effect of laparoscopy on the treatment of ovarian cysts and its effect on the function of ovary WANG Cui-rong Objective To analyze the effect of laparoscopic treatment of ovarian cyst and its effect on the function of ovary.Methods Forty patients with ovarian cyst from March 2015 to March 2016 in our hospital were randomly selected for study,and they were randomly divided into observation group and control group,with 20 cases in each group.The control group was treated with conventional open surgery,and the observation group was treated with laparoscopic operation.At the same time,the treatment effect of patients was observed and recorded;the operation time,amount of bleeding during the operation,use of the anus and the usage of antibiotics,the situation of the sinus of patients were recorded. Results The operation time of patients in the observation group were significantly shorter than that of the control group, the difference was statistically significant(P＜0.05);the anal exhaust time of the observation group was significantly sooner than the control group,the difference was statistically significant(P＜0.01);the blood loss during the operation,the use of antibiotics and complications of the observation group were significantly better than those of the control group,the differences were statistically significant(P＜0.05).Before and 3,6 months after surgery,there was no statistically significant difference in the number of the antral follicle between the two groups(P＞0.05);the peak time of pregnancy and pregnancy of the observation group was significantly better than the control group,the difference was statistically significant(P＜0.05).Conclusion The curative effect of laparoscopic surgery in the treatment of patients with ovarian cyst is superior to laparotomy,shorten the operation,reduce the amount of bleeding in operation and the use of antibiotics,and lower the probability of occurrence of complications,it is worthy of clinical adoption. 2017 Vol. 24 (1): 95-97 [Abstract] ( 123 ) HTML (31 KB)  PDF  (0 KB)  ( 33 ) 98 Analysis of the early identification and prevention of postpartum hemorrhage ZHANG Fei-xue；MOU Hong-jiang；HUANG Tai-hua；MA Li Objective To analyze the causes of postpartum hemorrhage,early identification,reduce postpartum hemorrhage and maternal mortality.Methods Case date of 358 dead maternal caused by postpartum hemorrhage in Guizhou Province from January 2005 to December 2014 were retrospectively analyzed.Results Postpartum hemorrhage took the first place among the causes of maternal death,of which uterine inertia was the primary cause;postpartum hemorrhage caused by maternal mortality occurred mainly within 4 hours after delivery,followed by 4-12 h.Conclusion A high degree of vigilance 4 hours after delivery can be taken by accurately estimating the amount of blood loss,deal the third stage of labor actively,massage the uterus postpartum 2 hours regularly,active treatment of uterine atony,focusing on prevention of high risk factors and preventive drugs,can reduce the incidence of postpartum hemorrhage in a large extent,and lower the death rate of maternal caused by postpartum hemorrhage. 2017 Vol. 24 (1): 98-100 [Abstract] ( 121 ) HTML (34 KB)  PDF  (0 KB)  ( 27 ) 101 Research and analysis of self-consciousness level of children with attention deficit hyperactivity disorder CHEN Kui-huan Objective To explore the level of self-awareness in children with attention deficit hyperactivity disorder (ADHD).Methods Forty-two children with ADHD were selected from August 2014 to August 2016,and 42 healthy children in our hospital were selected as the control group.The self-awareness of the two groups of children was measured and compared using the Rivet Test Combined(CRT)and the Piers-Harris Children′s Self-Consciousness Scale (PHCSS).Results The scores of behavior,intelligence and school,physical and attribute,anxiety,gregariousness,happiness and satisfaction and total score of PHCSS were significantly higher than those of the control group(P＜0.01).The level of IQ in the study group(102.55±11.56)was significantly lower than that of the control group(115.12±10.75),the difference was statistically significant(P＜0.01).The level distribution of IQ between the two groups had statistically significant difference(P＜0.05).The level of self-consciousness in the study group was significantly lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion The level of self-awareness of children with ADHD is significantly lower than that of healthy children,which has a certain relationship with parents′education.Therefore,parents should to correct their attitude and manner of education,and strengthen the behavior of children to intervene in order to enhance their self-esteem level of self-awareness and promote their healthy growth. 2017 Vol. 24 (1): 101-103转115 [Abstract] ( 120 ) HTML (36 KB)  PDF  (0 KB)  ( 39 ) 104 Analysis of clinical value of Pituitrin and Methotrexate for the treatment of tubal pregnancy under laparoscopy WEN Li-ping Objective To observe and analyze the clinical value of Pituitrin and Methotrexate for the treatment of tubal pregnancy under laparoscopy.Methods Sixty cases of laparoscopic tubal pregnancy and who treated by laparoscopic in our hospital from January to October in 2016 were selected as the research objects,and were divided into two groups，study group and control group,with 30 cases in each group.Patients in the study group were treated with local injection of Pituitrin and Methotrexate while patients in the control group were not treated with drug.Then,the operation time,the amount of bleeding,the bleeding time,the changes of the level of β-HCG after operation and the occurrence of postoperative persistent ectopic pregnancy of patients in the two groups were compared.Results The operation time,bleeding volume,bleeding time in the study group were significantly better than those in the control group,the differences were statistically significant(P＜0.01);the decreased level of β-HCG in the study group 1,2 weeks after operation was significantly lower than that in the control group,the difference was statistically significant(P＜0.01);the incidence rate of persistent ectopic pregnancy and tubal patency rate of patients after operation in the study group were significantly better than those in the control group,and the differences were statistically significant(P＜0.01).Conclusion The injection of Pituitrin and Methotrexate in patients with tubal pregnancy undergoing laparoscopic can effectively protect the fallopian tube of patients,reduce the operation time and the amount of bleeding,and significantly lower the incidence of persistent ectopic pregnancy,it have significant benefits for patients with pregnancy,thus it is worthy to be promoted and applied in clinical. 2017 Vol. 24 (1): 104-106 [Abstract] ( 136 ) HTML (32 KB)  PDF  (0 KB)  ( 33 ) 107 Feasibility and safety analysis of disposable cervical dilator balloon in the induction of term pregnancy ZHANG Qiu-yue；Narengaowa Objective To evaluate the feasibility and safety of labor induction of full-term pregnancy application disposable cervical balloon dilator.Methods From January 2015 to January 2016,200 cases of patients with full-term pregnancy,single fetal head position,and planned labor induction in our hospital were selected as the study objects, among which 100 cases used the oxytocin induced abortion were served as the control group,100 cases taken oxytocin combined with induction of disposable cervical balloon dilator were served as the observation group.The cervical maturity and delivery success rate of the two groups were compared and analyzed.Results The Bishop score in the observation group was better than the control group,the difference was statistically significant(P＜0.01);the total effective rate of the observation group was better than the control group,the difference was statistically significant(P＜0.01);the first stage and the second stage of labor time of the observation group was better than those of the control group,the difference was statistically significant(P＜0.01);the Apgar score and the amount of postpartum hemorrhage had no significant difference between two groups(P＞0.05).Conclusion Applying one-off cervical balloon expander to full-term pregnancy induced labor can promote cervical mature,shorten the labor,improve the success rate of childbirth,effectively ensure the security of maternal and infant,high feasibility,worthy of clinical popularization and application. 2017 Vol. 24 (1): 107-109 [Abstract] ( 120 ) HTML (32 KB)  PDF  (0 KB)  ( 43 ) 110 Comparison the effect and complication of laparoscope and open abdominal in uterine fibroids elimination JIANG Hai-zhan Objective To compare the clinical effect of laparoscope and open abdominal uterine fibroids elimination,and to evaluate the complications.Methods One hundred patients with uterine fibroid from March 2012 to March 2014 in our hospital were selected and conducted uterine fibroids elimination after confirmation.Patients were divided into two groups according to admission order,50 patients in observation group were treated by the laparoscope uterine fibroids elimination and 50 patients in control group were treated by the open abdominal uterine fibroids elimination.All patients were followed up for 2 years and 6 months.The hospital stay,operation time,bleeding during operation,postoperative anal exhaust time,postoperative bed activity time,pregnancy rate after operation and symptom relief rate after operation in two groups were recorded and analyzed.The complications and incidence rate of total complications of peripheral organ injury,postoperative residual tumour,menstrual cycle disorder and myoma recurrence were compared.Results The hospital stay,operation time,bleeding during operation,postoperative anal exhaust time and postoperative bed activity time in observation group were respectively(3.52±2.23)d,(57.62±12.34)min,(82.87±28.03)ml,(18.58±5.01)h,and(10.35±2.66)h, which were obvious lower than those of the control group[(7.03±2.68)d,(78.53±21.42)min,(141.12±31.63)ml,(21.36± 6.72)h,(12.88±3.75)h];pregnancy rate after operation was 84.0%,was obvious higher than that in control group(66.0%), and the differences were statistical significance(P＜0.05).The incidence rate of total complications in observation group was 2.0%,was obvious lower than that in control group(14.0%),and the difference was statistical significance(P＜0.05). Conclusion Laparoscope uterine fibroids elimination with the advantages of shorter operation time,less bleeding during operation,fast postoperative recovery and little complications,it is a safety operation. 2017 Vol. 24 (1): 110-112 [Abstract] ( 125 ) HTML (32 KB)  PDF  (0 KB)  ( 34 ) 113 Application of Nilestriol combined with Misoprostol in removal of intrauterine device for postmenopausal women HE Ying Objective To explore the application effect of Nilestriol combined with Misoprostol in the removal of intrauterine device for postmenopausal women.Methods 120 cases of postmenopausal women with IUD removed from January 2014 to December 2015 in our hospital were selected and randomly divided into observation group and control group,60 cases in each group.The control group was not use any drugs before operation of drawing the IUD,the observation group was given the Nilestriol 6 mg one week before operation,and Misoprostol Tablets 400 μg was placed in the posterior vaginal fornix 4 hours preoperative.The degree of cervical softening,the effect of the surgery and intraoperative pain of the patients in the two groups were observed and compared.Results The cervical softening rate of the observation group was 95.00%,it was significantly higher than that of the control group（75.00%）,there was significant statistical difference（P＜0.05）.The success rate of the observation group was 100.00%,it was significantly better than that of the control group（81.67%）,the difference was statistically significant（P＜0.05）.The VAS scores of the observation group was（1.46±0.58）scores,which was significantly lower than that of the control group（3.44±0.87）scores,the difference was statistically significant（P＜0.05）.Conclusion The combined application of Nilestriol and Misoprostol in removal of intrauterine device for postmenopausal women,can effectively soften the cervix,improve the success rate of IUD removal, and the pain degree of patients is lower,it is worthy of extensive promotion. 2017 Vol. 24 (1): 113-115 [Abstract] ( 120 ) HTML (32 KB)  PDF  (0 KB)  ( 36 ) 116 Evaluation of the effect of Misoprostol combined with oxytocin on the induction of labor in late pregnancy and adverse reactions HUANG Rong-di；LIANG Jin-lun Objective To explore the effect of Misoprostol combined with oxytocin on the induction of labor in late pregnancy and adverse reactions.Methods A total of 216 pregnant women who were hospitalized in Shijie Hospital of Dongguan City from March 2014 to March 2016 were selected as research subjects,and they were randomly divided into observation group and control group,with 108 cases in each group.The observation group was given vaginal administration of Misoprostol combined with oxytocin intravenous infusion for induction of labor,and the control group was given intravenous drip of oxytocin alone.The successful rate of induction of labor,total effective rate of induction of labor,time of induction of labor,cesarean section rate,postpartum hemorrhage rate,fetal distress rate and neonatal asphyxia rate were observed and compared between the two groups.Results The successful rate of induction was 93.5%and 81.5%in the observation group and the control group respectively,the total effective rate was 98.1%and 85.2%respectively,and the successful rate and the total effective rate in the observation group was higher than those in the control group respectively,the difference was statistically significant(P=0.014,0.002);the time of induction of labor in the observation group was shorter than that in the control group[(12.1±1.9)h vs.(19.0±2.0)h],and the difference was statistically significant(P=0.000);the rate of cesarean section in the observation group was lower than that in the control group (25.9%vs.39.8%),and the difference was statistially significant(P=0.027).There were no statistically significant differences in terms of postpartum hemorrhage(5.5%vs.6.5%,P=0.762),fetal distress(8.3%vs.10.2%,P=0.623),and neonatal asphyxia(4.6%vs.3.7%,P=0.744)between the two groups.Conclusion Low dose of Misoprostol combined with oxytocin can increase the successful rate of induction of labor,shorten induction time,increase the rate of vaginal delivery and do not increase the adverse outcome of mother and child. 2017 Vol. 24 (1): 116-118 [Abstract] ( 121 ) HTML (33 KB)  PDF  (0 KB)  ( 29 ) 119 Application value of real-timethree-dimensional transesophageal echocardiography in evaluating the morphology of patent foramen ovale in adults YUE Qing-xiong；LI Shi-jun；ZHOU Yu；LIU Jia Objective To evaluate the application value of real-time three-dimensional echocardiography(RT3D-TEE) in the evaluation of the morphology of patent foramen ovale(PFO)in adults.Methods 32 patients with PFO in our hospital from December 2013 to October 2016 who underwent two-dimensional transesophageal echocardiography(2DTEE)and RT3D-TEE before surgery to measure the channel length,inlet width,middle width and exit width of foramen ovale,and measurement result was compared.Different types of occlude were choosed according to the PFO width at entrance and involutory length measured by 3D-TEE measurement.Results 18/25 mm occlude was selected in 24 cases, and 8 cases with 30/30 mm occlude.There was no statistical difference of channel length of oval foramen measured by 2D-TEE and RT3D-TEE(P＞0.05).Inlet width,middle width and exit width of foramen ovale measured by RT3D-TEE was larger than those of 2D-TEE(P＜0.05).TEE examination was conducted after plugging to show that there was no residual shunt.Conclusion RT3D-TEE can clearly display the three-dimensional structure of the foramen ovale and provide more accurate information about the shape of the foramen ovale. 2017 Vol. 24 (1): 119-121 [Abstract] ( 103 ) HTML (32 KB)  PDF  (0 KB)  ( 36 ) 122 Clinical significance of SPECT/CT99mTcimaging in differentiated thyroid carcinoma before131I treatment imaging in differentiated thyroid carcinoma before131I treatment[J]. 中国当代医药, 2017,24(1): 122-124转131')" href="#"> ZHANG Shu-long；ZHAN Lei Objective To investigate the significance of SPECT/CT99Tcmimaging in the assessment of residual thyroid tissue and the metastasis of differentiated thyroid carcinoma(DTC)before131I treatment.Methods 72 patients with DTC treated in our hospital from November 2013 to August 2016 were collected and treated with131I.Before the implementation of131I treatment,99TcmSPECT/CT thyroid static imaging was conducted,and the range included neck,chest, and fault fusion imaging was conducted routinely in neck and chest.After 5-8 days131I treatment,whole-body imaging (Rx-WBS)was conducted,and fault fusion imaging was conducted routinely in neck and chest,and other parts of the abnormal uptake foci was added with fault fusion imaging.Two kinds of imaging results were compared before and after treatment.Results99TcmSPECT/CT imaging and therapeutic dose of131I SPECT/CT imaging showed that the positive rate of residual thyroid was 90.3%(65/72),97.2%(70/72)respectively.The coincidence rate was 93.1%(67/72)between99TcmSPECT/CT imaging before treatment and131I99TcmSPECT/CT imaging after treatment.Among 72 patients with131I treatment,7 cases of therapeutic doses of131I SPECT/CT imaging for lymph node or lung metastasis and bone metastasis,and the corresponding parts of abnormal uptake lesions was found in 5 cases by99TcmSPECT/CT thyroid imaging.Transfer consistency was 71.4%(5/7)found.Conclusion99TcmSPECT/CT thyroid imaging conducted before131I treatment for differentiated thyroid carcinoma not only can well understand the residual thyroid,but also can find some metastatic lesions before treatment,and it has a very guidence significance for evaluation and development of therapeutic dose before treatment. 2017 Vol. 24 (1): 122-124转131 [Abstract] ( 124 ) HTML (50 KB)  PDF  (0 KB)  ( 24 ) 125 Transvaginal color Doppler ultrasound diagnosis and clinical treatment of uterus scar pregnancy after cesarean section surgery QI Liu-qing；LIN Jian-zhai；CHEN Jing-chai；ZOU Ye-ping；LIU Yong-dan Objective To explore the application value of transvaginal color Doppler ultrasound diagnosis and treatment of uterus scar pregnancy after cesarean section operation.Methods The clinical data of 238 patients with uterus scar pregnancy after cesarean section operation treated in the hospital from May 2012 and July 2016 were retrospectively analyzed.The transvaginal color Doppler ultrasound images,diagnosis and treatment plans of patients were analyzed.Results Among 238 cases,there were 98 cases of exophytic gestational sac type,128 cases of endogenous gestational sac type and 12 cases of mixed mass type.The patients with exophytic gestational sac type were treated with laparoscopic surgery or laparoscopy combined with hysteroscopy surgery.Among patients with endogenous gestational sac type,78 cases underwent bilateral uterine artery embolization,36 cases underwent the combination of bilateral uterine artery embolization and curettage,and 14 cases underwent line bilateral uterine artery embolization combined with MTX.Among 12 patients with mixed mass type,4 cases underwent uterine artery embolization,7 cases underwent uterine artery embolization combined with uterine curettage and 1 case underwent hysterectomy.All patients were followed up for 3 months,all patients who had not been removed from the uterus recovered menstruation.Conclusion Transvaginal color Doppler ultrasound has an improtant guidance in the early diagnosis and treatment of uterine scar pregnancy after cesarean section and should be popularized and applied in clinic. 2017 Vol. 24 (1): 125-128 [Abstract] ( 114 ) HTML (41 KB)  PDF  (0 KB)  ( 34 ) 129 Vaginal color Doppler ultrasound applied to explore the influence of hydrosalpinx on endometrial receptivity MA Liang-di Objective To analyze the influence of hydrosalpinx on endometrial receptivity applying Vaginal color Doppler ultrasound.Methods 80 patients with hydrosalpinx treated by our hospital from January 2012 to January 2015 were selected and they were divided into the experimental group A(unilateral hydrosalpinx group,n=40)and the experimental group B(bilateral hydrosalpinx group,n=40)according to the number random principle.Another group of 40 healthy women who already gave birth in the same period was selected as the control group.The blood flow resistance index(RI)of uterine artery and blood flow distribution among three groups were compared.Results In the experimental group A having hydrocele and experimental group B,RI value of blood flow in the uterine artery was obviously higher than that in the control group(P＜0.05).There was no statistical difference in RI value of blood flow in the uterine artery in experimental group A having hydrocele and experimental group B(P＞0.05).The percentage of type A and type C in the experimental group A was higher than that in the control group.The percentage of type A in the experimental group B was higher than that in control group(P＜0.05).Conclusion Hydrosalpinx will have certain influence on uterine artery hemodynamics,which increases blood flow resistance and reduces endometrial and subintimal blood flow,and decreases endometrial receptivity. 2017 Vol. 24 (1): 129-131 [Abstract] ( 128 ) HTML (30 KB)  PDF  (0 KB)  ( 31 ) 132 Application value of transvaginal color Doppler ultrasound examination on the diagnosis of ectopic pregnancy of gynecological emergency LONG Zheng-xi；SONG Yan Objective To study the application value of transvaginal color Doppler ultrasound on the diagnosis of ectopic pregnancy of gynecological emergency.Methods Diagnostic data of 160 patients with ectopic pregnancy diagnosed by laparoscopic or open surgery in our hospital from July 2012 to May 2016 were retrospectively analyzed.All patients were given transabdominal(transabdominal ultrasound)and transvaginal color Doppler ultrasonography(transvaginal sonography)examination.The detection rate between the two examination methods was compared.Results The detection rate of fetal cystic,attenuation mass type,mixed mass type,solid mass type,float type,special type of tubal ectopic pregnancy of transvaginal ultrasound were higher than those of transabdominal ultrasound(P＜0.05).There was no statistical difference of the detection rate of ovarian pregnancy,cornual pregnancy,rudimentary cornual pregnancy between the two examination methods(P＞0.05).The mass diameter of transvaginal sonography examination concentrated in 2-3 cm,and this result was consistent with the final results,while the mass diameter of transabdominal ultrasound examination concentrated in 4-5 cm,and there was a statistical difference between the two examination methods(P＜0.05).Conclusion Transvaginal sonography has an important value in the diagnosis of ectopic pregnancy of gynecological emergency,and the detection rate is high,and the result is closer to the final results.It is worthy of promotion Application value of transvaginal color doppler ultrasound on the diagnosis of gynecological acute ectopic pregnancy.Diagnosis rate is high, and the end result is more close,worth promoting. 2017 Vol. 24 (1): 132-134 [Abstract] ( 115 ) HTML (31 KB)  PDF  (0 KB)  ( 39 ) 135 Significance and value of ultrasound examination in the diagnosis and treatment of scar pregnancy LUO Li-fang；ZHENG Xiao-hong；ZHU Yan-fang；WU Hui-shuang；DENG Jin-yao Objective To explore the clinical significance and value of ultrasound examination in the diagnosis and treatment of scar pregnancy.Methods From January 2015 to January 2016,40 suspected cases with scar pregnancy treated by our hospital were selected,and they were given ultrasound examination,and ultrasound examination result and operation result was compared.The correct rate of ultrasound diagnosis was counted.Results 39 cases(97.5%)were uterus scar pregnancy found by ultrasound examination,and 40 cases(100.0%)were uterus scar pregnancy found by operation. Compared with before operation treatment,muscle thickness decreased(P＜0.05),cervical length had no obvious change (P=0.93).Conclusion Ultrasound examination has a high accuracy rate for the diagnosis of uterine scar pregnancy,and it has a guidence role for subsequent surgical treatment. 2017 Vol. 24 (1): 135-137 [Abstract] ( 116 ) HTML (34 KB)  PDF  (0 KB)  ( 31 ) 138 Effect of Ketotifen combined with Loratadine in the treatment of children with cough variant asthma XIE Xiao-lan；ZENG Qing Objective To study effect of Ketotifen combined with Loratadine in the treatment of children with cough variant asthma.Methods 80 children with cough variant asthma in our hospital from February 2015 to February 2016 were selected and randomly divided into observation group and control group by computers,40 cases in each group.Patients of two groups were treated with conventional therapy,patients in the observation group were treated with Ketotifen combined with Loratadine,patients in the control group were treated with Ketotifen.Improvement time of clinical symptoms,pulmonary ventilation function,inflammatory factor level,adverse reaction and recurrence rate in two groups were compared.Results Improvement time of clinical symptoms,changes of pulmonary ventilation function and level of inflammatory factors in the observation group was better than that in the control group(P＜0.05).Incidence rate of adverse reaction(10.0%)in the observation group was significantly lower than that in the control group(17.5%),but the difference was not statistically significant(P＞0.05).Relapse rate(7.5%)in the observation group was lower than that in the control group(25.0%),the difference was statistically significant(P＜0.05).Conclusion Ketotifen combined with Loratadine in the treatment of children with cough variant asthma can improve the clinical symptoms,is safe and effective,which has a high clinical value. 2017 Vol. 24 (1): 138-140 [Abstract] ( 137 ) HTML (35 KB)  PDF  (0 KB)  ( 29 ) 141 The clinical effect of Naloxone combined with Xingnaojing in the treatment of acute alcoholism ZHOU Shang-ce；FANG Zhi-jian；YUAN Shan-tao；YUAN Zhuo-cheng；CHEN Qian-ping；MA Xiang-yun； CHEN Yong-ling Objective To investigate the clinical effect of Naloxone combined with Xingnaojing in the treatment of acute alcoholism.Methods 180 cases with acute alcoholism treated in our hospital were randomly divided into two groups from January 2014 to June 2016.The control group was treated with Naloxone alone,while the observation group was treated with Naloxone combined with Xingnaojing.The curative effect,improvement time of symptom and the incidence rate of adverse reaction in patients betwee two groups was compared.Results The total effective rate of the observation group(96.67%)was significantly higher than that of the control group(80.00%),the difference was statistically significant(P＜0.05).Consciousness recovery time,drug onset time,improvement time of symptom and disappear time of symptom in the observation group was significantly shorter than that of the control group respectively,and the difference was statistically significant(P＜0.05).Th incidence rate of advers reactions(nausea,vomiting,elevated blood pressure and arrhythmia and so on)in the observation group was significantly lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion Naloxone combined with Xingnaojing in the treatment of acute alcoholism has obvious curative effect,and can quickly improve symptoms,promote the recovery of consciousness with fewer adverse reactions.It has positive clinical significance. 2017 Vol. 24 (1): 141-143 [Abstract] ( 141 ) HTML (35 KB)  PDF  (0 KB)  ( 32 ) 144 Study on clinical application of traditional Chinese medicine contracting prescription for nourishing kidney and activating blood circulation in infertile patients with kidney deficiency syndrome XU Lu；XU Du-juan；HU Fa-ming；MEI Jin-feng；FAN He-hua；ZHAO Yu-hua Objective To explore the clinical efficacy of contracting prescription of traditional Chinese medicine for nourishing kidney and activating blood circulation in infertile patients with kidney deficiency syndrome.Methods 101 infertile patients with kidney deficiency syndrome,who were in line with the indication for artificial insemination and received treatment in our department from February to October in 2013 were selected and randomly divided into the control group(54 cases)and the traditional Chinese medicine group(47 cases).The control group was detected follicular development in the natural state,The traditional Chinese medicine group was treated with contracting prescription of traditional Chinese medicine for nourishing kidney and activating blood circulation.The treatment effect of the two groups was compared.Results The intima thickness of the traditional Chinese medicine group was thicker than that of the control group,the levels of E2and P in the traditional Chinese medicine group was higher than that of control group, the number of follicles in the traditional Chinese medicine group was more than that in control group,with significant difference(P＜0.05).The cycle pregnancy rate of the traditional Chinese medicine group was 29.8%,which was higher than 22.2%of the control group,with significant difference(P＜0.05).Conclusion The application of contracting prescription of traditional Chinese medicine for nourishing kidney and activating blood circulation in the treatment of infertility with kidney deficiency syndrome can significantly improve the ovarian function and the clinical efficacy is significant.It is worthy of clinical promotion and application. 2017 Vol. 24 (1): 144-146转149 [Abstract] ( 112 ) HTML (35 KB)  PDF  (0 KB)  ( 26 ) 147 Effect observation of Modified Maxingshigan Decoction in the treatment of children bronchial pneumonia QIU Li-na；CHENG De-zhen Objective To explore the effect of Modified Maxingshigan Decoction in the treatment of children bronchial pneumonia.Methods 100 cases of children with bronchial pneumonia in our hospital from January to June in 2015 were selected and randomly divided into the control group and the treatment group,50 cases in each group.The control group was treated with the routine treatment of western medicine,and the treatment group was treated with Modified Maxingshigan Decoction on the basis of the control group.The time of cough significantly reduced,pyretolysis time,pulmonary rales duration,lung X ray normal time,the time of white blood cell count in normal in the two groups were compared. Results The total effective rate of the treatment group was 98.0%,which was higher than 84.0%of the control group, with significant difference(P＜0.05).The time of cough significantly reduced,pyretolysis time,pulmonary rales duration, lung X ray normal time,the time of white blood cell count in normal in the treatment group was shorter than that in the control group,with significant difference(P＜0.05).Conclusion The effect of Modified Maxingshigan Decoction in the treatment of children bronchial pneumonia is significant,it is worthy of clinical promotion and application. 2017 Vol. 24 (1): 147-149 [Abstract] ( 130 ) HTML (33 KB)  PDF  (0 KB)  ( 32 ) 150 Analysis of outpatient pharmacy service and rational drug use in primary hospital GAN Huo-rong；XU Bing-lin；MAI Zhi-chang Objective To explore the influence of pharmacy service in basic hospital outpatient service on improving the level of rational drug use.Methods 188 patients accepted investigation from January 2014 to December 2015(not carrying out pharmacy service)and from January to June in 2016(carrying out pharmacy service)in our hospital outpatient department were selected as the research object,the two survey results was analyzed,the influence of pharmacy service on improving the level of rational drug use of outpatients department in primary hospital was summarized.Results The score of cognition of daily drug use,the cognition of antibiotic use,the time of drug use and the cognition of drug consumption and other drug knowledge cognition after carrying out pharmacy service were higher than that before carrying out pharmacy service,with significant difference(P＜0.01).Conclusion To carry out pharmacy service in primary hospital outpatient department can significantly improve people′s understanding of rational drug use. 2017 Vol. 24 (1): 150-152 [Abstract] ( 140 ) HTML (30 KB)  PDF  (0 KB)  ( 35 ) 153 Effect evaluation of setting up intravenous drug allocation center in our hospital GAO Yan-ling；ZHONG Xiu-juan；LIU Ze-qing；LUO Zhu-he Objective To investigate the effect of intravenous drug centralized allocation in our hospital,and to explore its effect on clinical rational drug use.Methods The quantity and audit results of intravenous medication in pharmacy intravenous admixture services(PIVAS)from January 2015 to June 2016 were counted and analyzed.The correct intervention plan and the physician′s feedback data after interventing were collected to observe the influence of audit intravenous medication on rationality of drug use.The dispensed time for nurse was counted to observe its influence on nursing time.The volume of drug storage in clinical was counted to observe its influence on drug management.Results The results showed that there were 994 208 audit intravenous medication orders,the unreasonable doctor were 2585(0.26%), which amended unreasonable doctor were 2204,clinical correction rate was 85.26%.The dispense time of nurse was significantly reduced,the nursing time was increased and the quality of nursing was improved.The management of drug was more standardized with the reduction of the kind and quantity of intravenous medication,and the safety of medication was improved.Conclusion Intravenous drug allocation plays an important role in promoting rational drug use. 2017 Vol. 24 (1): 153-155 转158 [Abstract] ( 124 ) HTML (34 KB)  PDF  (0 KB)  ( 33 ) 156 The clinical study of neonatal blood sampling of femoral vein puncture LAN Hong Objective To investigate neonatal femoral vein blood collection technology improved and its value in clinical application.Methods 200 hospitalized neonates in our hospital from January to August 2015 in neonatal ward were selected and randomly divided into control group and observation group,100 cases in each group.The control group was used the traditional femoral vein puncture method,the observation group was used the improved oblique puncture method for femoral vein puncture blood collection,the effect of blood collection technique in two groups were compared. Results Complete the operation time of observation group was shorter than that of control group(P＜0.05);one time successful puncture rate was significantly higher than that of control group,the difference was significant(P＜0.05);the observation group blood specimen hemolysis and puncture tissue injury were significantly lower than those of control group,the differences were significant(P＜0.05).Conclusion Using the improved femoral venous puncture method can significantly shorten the operation time,improve the success rate of first puncture,reduce blood specimen hemolysis and puncture tissue injury incidence,improve work efficiency,reduce the pain of patients,improve the satisfaction of parents of children. 2017 Vol. 24 (1): 156-158 [Abstract] ( 96 ) HTML (32 KB)  PDF  (0 KB)  ( 39 ) 159 Observation of pediatric allergic purpura and study of its clinical nursing methods OUYANG Zhi-ming；YE Yong-qing；LIU Yu-ling；WEI Ke-ying；CHEN Bing；ZHOU Rong-feng Objective To explore the clinical nursing methods and nursing effect on pediatric allergic purpura.Methods 200 patients with pediatric allergic purpura were admitted into our hospital from January 2014 to December 2015,they were selected and evenly divided into two groups,100 cases in each group.In control group was applied regular nursing intervention,while in observation group were adopted targeted nursing intervention on the basis of the control group.The abdominal remission time,disappearing time of rash,and hospital stay were compared in both groups.Besides,the parents′anxiety score,disease uncertainty score,and nursing satisfaction were compared in two groups.Results The abdominal remission time,disappearing time of rash,and hospital stay of observation group were shorter than those of control group (P＜0.05).After nursing intervention,the anxiety score and disease uncertainty score of observation group were lower than before intervention(P＜0.05),and shorter than that of control group after intervention,the differences were significant(P＜0.05).The nursing satisfaction of parents in the observation group much higher than that of control group(P＜0.05). Conclusion Application of targeted intervention in pediatric patients with allergic purpura not only promotes remission of clinical symptoms,but also improves parents′mental state as well as nursing satisfaction. 2017 Vol. 24 (1): 159-161 [Abstract] ( 126 ) HTML (34 KB)  PDF  (0 KB)  ( 25 ) 162 Clinical application of evidence-based nursing on preventing of complicationg in patient with prone position spinal surgery ZHONG Huang-jiao；WANG Wen-lan；YOU Yu-yuan Objective To study the clinical application of evidence-based Nursing(EBN)on preventing of complicationg in patient with prone position spinal Surgerythe.Methods 192 patients for prone position spinal surgery from January 2014 to January 2016 were selected and randomly divided into the observation group and the control group,96 cases in each group.The control group was given routine decubitus preventive measures，while the observation group was given EBN decubitus prevention measures.Results The incidence rate of complication of observation group was 5.21% statistically lower than that of the control group(28.13%)(P＜0.05);the satisfaction of patients,surgical doctor and anesthetist in the observation group were significantly higher those that of control group，the differences were statistically significant(P＜0.05).Conclusion EBN can decreased complicationg in patient with prone position spinal,and improve the safety of operation.EBN can promote the development of nursing service to the scientific,individual and humanized.Therefore,it is worth popularizing and applying. 2017 Vol. 24 (1): 162-164 [Abstract] ( 144 ) HTML (32 KB)  PDF  (0 KB)  ( 39 ) 165 Clinical effect of high-quality nursing care in the laparoscopic surgery of ovarian neoplasm YE Xiao-qin；CHEN Yu-qun Objective To explore the effect of high quality nursing care in the treatment of patients with ovarian tumor after laparoscopic operation.Methods 72 patients with ovarian neoplasm were treated from February 2015 to February 2016 in our hospital were selected and were randomly divided into control group and high quality group according to the order in hospital,36 cases in each group,they were given laparoscopic surgery.The control group were adopted the conventional nursing care in the perioperative period,the quality group were given the high-quality nursing care on the base of control group.The hospitalization time,the patient′s satisfaction and life quality were comparmed.Results The satisfaction of control group was 77.78%,the satisfaction of high quality group was 91.67%(P＜0.01);the recovery time and hospitalization time of control group were longer than those of high quality group(P＜0.01);the evaluation score of social integration,physical function,mental state,family relation and degree of recognition in control group were lower than those of high quality group(P＜0.01).Conclusion During the laparoscopic surgery of ovarian neoplasm,the highquality nursing care can improve the patient′s satisfaction and life quality,promote the patient′s fast recovery and shorten the hospitalization time. 2017 Vol. 24 (1): 165-167 [Abstract] ( 131 ) HTML (32 KB)  PDF  (0 KB)  ( 32 ) 168 Laparoscopic resection in patients with uterine fibroids perioperative nursing experience LIU Chan-juan Objective To investigate the effect of the perioperative period nursing in patients undergoing Laparoscopic uterine fibroids surgery.Methods 74 patients undergoing laparoscopic uterine fibroids surgery from August 2014 to August 2016 were selected and randomly divided into two groups,37 cases in each group.the control group was given routine nursing,the observation group was given perioperative period holistic nursing.Results The operating time,amount of bleeding in observation group were compared with control group,there were no significantly differences(P＞0.05);the hospitalization days were(5.67±0.83)d in observation group were less than those of control group(8.18±1.04)d(P＜0.05);10 min after establishing pneumoperitoneum,the heart rate,mean arterial pressure,blood glucose in observation group were lower than those of control group（P＜0.05）;at the end of the surgery,the heart rate,mean arterial pressure, blood glucose in observation group were lower than those of control group（P＜0.05）;the complication rate in observation group was 10.81%,was lower than that of control group（35.14%）(P＜0.05).Conclusion The perioperative period nursing in patients undergoing laparoscopic uterine fibroids surgery can reduce the surgical stress,decrease the incidence of postoperative complications. 2017 Vol. 24 (1): 168-170 [Abstract] ( 126 ) HTML (32 KB)  PDF  (0 KB)  ( 23 ) 171 Continue nursing measures according to the medical behavior in patients with pulmonary tuberculosis and the influence of the quality of life WANG Li-jie Objective To explore the impact of extended nursing on patients with pulmonary tuberculosis and their quality of life.Methods 100 patients with pulmonary tuberculosis from April 2014 to April 2016 were selected and randomly divided into two groups according to computer,50 cases in each group.In the control group were given routine nursing care and discharge guidance,the patients in the observation group were treated with continuous nursing.The total compliance rate and quality of life factor scores were compared between two groups.Results The total compliance rate of the observation group(96.00%)was higher than that of the control group(52.00%),and the quality of life factor score was better than that of control group(P＜0.05).Conclusion The application of continual nursing measures in patients with pulmonary tuberculosis can effectively improve the compliance behavior and quality of life of patients. 2017 Vol. 24 (1): 171-172转175 [Abstract] ( 140 ) HTML (32 KB)  PDF  (0 KB)  ( 32 ) 173 Analysis of perioperative comfortable nursing in tension-free hernia repair for inguinal hernia surgery YE Miao-qin；LI Man-man Objective To explore the effect of comfortable nursing in inguinal hernia with tension-free repair.Methods 100 cases of inguinal hernia patients in our hospital from January 2014 to December 2016 were selected as research objects,they were divided into observation group and control group,50 cases in each group.Patients in control group were given routine care,but patients in observation group were carried out comfortable nursing on the basis of routine nursing care.The sleep quality,wound healing,heart rate and blood pressure,complications and satisfaction on nursing of two groups were compared.Results The rate of heart rate increase,perioperative blood pressure increase rate and complication incidence of observation group were significantly lower than those of control group,the differences were significant(P＜0.05).The perioperative sleep effective rate,the rate of wound healing of observation group respectively were significantly higher than those of control group(P＜0.05).The total satisfaction of the observation group was 100%,while the control group was 86%,with the difference was significant(P＜0.05).Conclusion The development of comfortable nursing mode can effectively improve the patient′s physical and mental with inguinal hernia with tension-free repair, and increase nursing satisfaction and quality of nursing. 2017 Vol. 24 (1): 173-175 [Abstract] ( 131 ) HTML (32 KB)  PDF  (0 KB)  ( 30 ) 176 Effect of staged rehabilitation nursing intervention on patients with hemiplegia after cerebral infarction GUO Qing-li；OU Qiu-yan；LIANG Jie-ying objective To explore the effect of staged rehabilitation nursing intervention on patients with hemiplegia after cerebral infarction.Methods 68 cases of cerebral infarction hemiplegia in our hospital from May 2014 to April 2016 were selected and randomly divided into observation group and control group,34 cases in each group,the control group was received routine nursing intervention,and the observation group was implemented the stage of rehabilitation nursing intervention,two groups of patients with clinical effect of the prognosis were compared.Results The clinical nursing compliance rate of the observation group was 97.06%,higher than that of control group significantly(67.65%),the motor function and life ability score were significantly better than those of control group(P＜0.05),and the quality of life score was higher than that of control group(P＜0.05).Conclusion The implementation phase of nursing intervention on rehabilitation of patients with cerebral infarction can significantly improve the patient′s clinical nursing compliance rate,improve the prognosis,and improve the clinical efficacy and quality of life,it is a worthy of clinical application of the nursing measures. 2017 Vol. 24 (1): 176-178 [Abstract] ( 103 ) HTML (33 KB)  PDF  (0 KB)  ( 34 ) 179 Effect of continuity of nursing on compliance of rehabilitation training and quality of life in elderly patients with femoral neck fracture MENG Zhi-hong Objective To explore the effect of continuing nursing on compliance of rehabilitation training and quality of life in elderly patients with femoral neck fracture.Methods 90 elderly patients with femoral neck fracture from June 2013 to March 2016 in our hospital were selected and randomly divided into observation group and control group,45 patients in each group.The control group were received traditional nursing intervention while the observation group were received continuing nursing intervention,the compliance of rehabilitation training,joint function,life quality and complication rate of two group were compared after following up for 6 months.Results The required time,part,action and initiative of rehabilitation training of the observation group were all significantly improved than those of control group (P＜0.01);the scores of hip and knee joint of two groups were all significantly higher after nursing intervention（P＜0.01）, while the score of the observation group was significantly higher than that of control group(P＜0.01);the score of life quality in observation group was all significantly higher than that of control group(P＜0.01),the complication incidence rate of observation group was 8.89%,lower than that of control group of 24.44%(P＜0.05).Conclusion Continuing nursing can achieve significant compliance of rehabilitation training and better life quality in elderly femoral neck fracture patients. 2017 Vol. 24 (1): 179-181转185 [Abstract] ( 130 ) HTML (36 KB)  PDF  (0 KB)  ( 33 ) 182 DAMIS cooperation of minimally invasive total hip arthroplasty HU Mei-Jiao；LI Zhen；CHEN Min Objective To discuss the nursing cooperation and experience in the DAMLS（direct anterior minimum invasive surgery）minimally invasive total hip replacement surgery.Methods Based on the regression analysis of the clinical data of 74 cases DAMIS routine total hip replacement surgeries from August 2013 to September 2015 in our hospital, the research summarizes the nursing cooperation and surgical care points.Through doing routine X-ray examination of patients′bilateral hip and pelvis to compare the preoperative and postoperative Harris hip scores to assess the efficacy of the surgeries,surgical nurses should prepare the required hip prosthesis,goods,equipment in advance,familiarize with the surgical procedures,in the surgery pay attention to aseptic surgery,and make careful inventory of equipment,needles, gauze and other small objects to prevent left over in the patients′body after the surgery.Nurses should monitor the patient′s temperature,protect the skin,do the postural care,give patient anesthesia,and observe the patient′s vital signs closely to offer active,quick and safe cooperation in the surgery.Results In the 76 cases of surgery,the average length of the incision was(9.5±1.5)cm,the operative time was(132.7±11.7)min,the blood loss was(219.4±104.6)ml,the number of days in hospital was(7.8±1.9)d,and none of the cases had following complications,lateral femoral cutaneous nerve injury symptoms,intraoperative fracture,deep infection,dislocation and so on.In the surgery,nursing was done safely and smoothly,and no care adverse events happened.Conclusion The DAMIS total hip replacement surgery protect the soft tissue well,and ensure less blood loss,which helps the patients recover the hip function rapidly,but the requirements of the surgical technique are relatively high,and the techniques need long-time learning.Adequate preparation before the surgery,skilled surgery cooperation and meticulous care before and after the surgery are key factors in ensuring the safety of the patients,the success of the surgery. 2017 Vol. 24 (1): 182-185 [Abstract] ( 129 ) HTML (40 KB)  PDF  (0 KB)  ( 33 ) 186 Effect of multidisciplinary collaborative comprehensive nursing intervention on postoperative activity of daily living in elderly with hip fracture ZHANG Lu Objective To investigate the effect of multidisciplinary collaborative comprehensive nursing intervention on postoperative activity of daily living in elderly with hip fracture.Methods 70 elderly with hip fracture from June 2015 to June 2016 in our hospital were selected and randomly divided into two groups,35 cases in each group.The control group were taken routine nursing,and on this basis observation group were taken multidisciplinary collaborative comprehensive nursing intervention.The total intervention time included hospital stays and 3 months after discharge,the hip joint function and ADL of two groups were compared.Results Three months after treatment,the Harris hip joint score of control group was(73.89±9.02)points,which was significantly lower than(84.39±8.69)points of observation group,there was statisticant difference(t=4.960,P＜0.05);the Barthel index score of control group was(75.26±9.12)points,which was significantly lower than(84.39±8.75)points of observation group,there was statisticant difference(t=4.274,P＜0.05). Conclusion Multidisciplinary collaborative comprehensive nursing intervention can effectively promote recovery of hip joint function,increase activity of daily living and improve living quality,which has higher clinical application value. 2017 Vol. 24 (1): 186-188 [Abstract] ( 125 ) HTML (33 KB)  PDF  (0 KB)  ( 34 ) 189 Effect,common problems and countermeasures of transfusion port in patients with breast cancer undergoing chemotherapy CHENG Yan-yun；CHEN Rong-xia；WU Qian-fang Objective To analyze the common problems in the application of transfusion port in the chemotherapy of breast cancer,and put forward the solution,to explore the application effect of transfusion port in the chemotherapy of breast cancer.Methods 158 cases of breast cancer treated by transfusion port in our hospital from January to December in 2014 were selected as the control group,the common clinical nursing problems were analyzed retrospectively,the causes were analyzed and the corresponding measures were put forward.180 cases of breast cancer treated by transfusion port in our hospital from January to December in 2015 were selected as the observation group,and the corresponding solutions were carried out in the nursing process.The incidence rate of adverse events and patient satisfaction were compared between the two groups.Results The incidence rate of adverse events in the observation group was lower than that in the control group,with significant difference(3.33%vs.13.29%,P＜0.05).The patients satisfaction score in the observation group was higher than that in the control group,with significant difference[(86.7±6.9)vs.(75.3±7.3),P＜0.05]. Conclusion In the treatment process of breast cancer chemotherapy patients treated by infusion port,the inspection and examination should be strengthened,the adverse events were analyzed,which can significantly improve the satisfaction of patients,reduce the incidence rate of adverse events. 2017 Vol. 24 (1): 189-191 [Abstract] ( 122 ) HTML (37 KB)  PDF  (0 KB)  ( 42 ) 192 Application research of painless ward management mode in postoperative patients with cholangiolithiasis LI Guo-ji；CHEN Jin-jian；LU Xiang-li；LI Chun-mei；LIU Li-ping Objective To explore the application effect of painless ward management mode in postoperative patients with cholangiolithiasis.Methods 30 cases of cholangiolithiasis treated in our hospital from January to May in 2016(before the establishment of painless ward)were selected as control group,30 patients with cholangiolithiasis treated in our hospital from June to October in 2016(after the establishment of painless wards)were selected as the experimental group. The control group was given routine nursing and health guidance,the experimental group was given painless ward management mode on the basis of routine nursing.The postoperative pain,ambulation time,intestinal ventilation time,sleep duration,hospitalization time and the degree of satisfaction were compared between the two groups.Results The pain score of the experimental group at 6,12,24,48,72 hours after operation was lower than that of the control group,with significant difference(P＜0.05).Postoperative ambulation time,intestinal ventilation time and hospitalization time in the experimental group was shorter than that in the control group,and the sleep duration and the degree of satisfaction in the experimental group was better than that in the control group,with significant difference(P＜0.05).Conclusion The effect of painless ward management mode in postoperative patients with cholangiolithiasis is significant,which is worthy of clinical promotion and application. 2017 Vol. 24 (1): 192-194 [Abstract] ( 122 ) HTML (32 KB)  PDF  (0 KB)  ( 35 ) 195 Application of comfortable nursing in patients with peptic ulcer LIU Lin；MA Na；ZHAO Xue-han Objective To analyze the application effect of comfort nursing in patients with peptic ulcer,and put forward reasonable nursing suggestion.Methods From January to December 2015,120 cases of peptic ulcer patients treated in our Department of Gastroenterology were divided into control group and experimental group by randon number table method,60 cases in each group.Patients in the control group were given routine nursing care,and patients in the experimental group were taken with comfortable nursing on the basis of the control group.The clinical symptom improvement rate,HP eradication rate,SAS score and satisfaction to nursing quality between two groups were were compared.Results The clinical symptom improvement rate,HP eradication rate was 91.7%in the experimental group,significantly higher than 66.7%in the control group(P＜0.05).SAS scores and nursing quality satisfaction scores in the experimental group was significantly higher than that in the control group(P＜0.01).Conclusion Comfortable nursing can help improve the efficacy in the treatment of peptic ulcer,and it is worthy of application. 2017 Vol. 24 (1): 195-197 [Abstract] ( 122 ) HTML (37 KB)  PDF  (0 KB)  ( 33 )

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