10例肾血管周上皮样细胞肿瘤临床病理分析

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Abstract Objective To explore the clinicopathologic characteristics of renal perivascular epithelioid cell tumors (PEComas).Methods 10 cases of renal PEComas confirmed by pathology from June 2013 to September 2015 in our hospital were followed up,the clinical pathological features were analyzed retrospectively and the treatment plan was summarized.Results In the 10 cases of renal PEComas,male to female ratio was 1∶9,their average age was(50.9±19.5) years old,with a median age of 40.5 years old.All 10 cases were treated by surgical resection.The average time of follow-up was(18.6±8.2)months,with a median follow-up time of 19.5 months.Disease-free survival were found in 7 cases,while two cases survived with tumors and one died.Maximum tumor length was(5.3±2.8)cm,with a median length of 5.1 cm,hemorrhage or necrosis were confirmed in five of them.9 cases were diagnosed as pure renal PEComa.One patient was found accompanied with urothelial cell carcinoma of the renal pelvis.All cases presented positively labeled with HMB45 and/or Melan-A,the average positive ratio of Ki67 was(7.0±6.1)%,with its medium 5.0%.Conclusion As clinical diagnose of renal PEComa is quite difficult,its diagnose mainly relies on pathological findings.Surgical resection is tended to treat this kind of patients.Most of them results well outcomes.For the tumors unable to removed or dealt with conservative treatment,this kind of patients should be closely followed-up.

Key words： Perivascular epithelioid cell tumors,Renal epithelioid angiomyolipoma Renal tumor Tumor therapy Clinicopathologic characteristic

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	LIN Le
	WEI Yong-bao
	LI Tao
	CHEN Zi-fu
	GAO Xiang-xun

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LIN Le,WEI Yong-bao,LI Tao, et al. Clinicopathologic analysis of 10 cases of renal perivascular epithelioid cell tumors[J]. 中国当代医药, 2017, 24(1): 4-8转15.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I1/4

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