前列腺素受体亚型FP-V2与早孕药物流产结局的分析

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Abstract Objective To compare of mRNA expression difference of FP,FP-V1 and FP-V2 in patients with complete abortion and incomplete abortion in early pregnancy deciduas.Methods 50 patients initiatived to require drug abortion termination of normal pregnancy from June 2013 to March 2015 in Liaoning Province Family Planning Research Institute Outpatient were selected as the research objecets,all patients were divided into the complete group(n=30)and the incomplete group(n=20)according to whether complete abortion.The expression difference of FP,FP-V1 and FP-V2 of early pregnancy decidua in the two groups were detected by real-time quantitative PCR.Results The MRNA expression of FP and FP-V2 in decidua in the incomplete group was higher than that in the complete group,with significant difference(P＜0.05).There was no significant difference in the expression of FP-V1 in the two groups(P＞0.05).Conclusion The higher expression of FP-V2 in human early pregnancy decidual may associated with incomplete abortion.

Key words： FP-V2 subtype Medical abortion Decidua Incomplete abortion Early pregnancy

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	MA Chao
	FENG Wen-hua
	HAN Wei-tian

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MA Chao,FENG Wen-hua,HAN Wei-tian. Analysis of prostaglandin receptor subtype FP-V2 and drug abortion outcome in early pregnancy[J]. 中国当代医药, 2017, 24(1): 9-11转58.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I1/9

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