尼尔雌醇联合米索前列醇在绝经后妇女节育器取出中的应用

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Abstract Objective To explore the application effect of Nilestriol combined with Misoprostol in the removal of intrauterine device for postmenopausal women.Methods 120 cases of postmenopausal women with IUD removed from January 2014 to December 2015 in our hospital were selected and randomly divided into observation group and control group,60 cases in each group.The control group was not use any drugs before operation of drawing the IUD,the observation group was given the Nilestriol 6 mg one week before operation,and Misoprostol Tablets 400 μg was placed in the posterior vaginal fornix 4 hours preoperative.The degree of cervical softening,the effect of the surgery and intraoperative pain of the patients in the two groups were observed and compared.Results The cervical softening rate of the observation group was 95.00%,it was significantly higher than that of the control group（75.00%）,there was significant statistical difference（P＜0.05）.The success rate of the observation group was 100.00%,it was significantly better than that of the control group（81.67%）,the difference was statistically significant（P＜0.05）.The VAS scores of the observation group was（1.46±0.58）scores,which was significantly lower than that of the control group（3.44±0.87）scores,the difference was statistically significant（P＜0.05）.Conclusion The combined application of Nilestriol and Misoprostol in removal of intrauterine device for postmenopausal women,can effectively soften the cervix,improve the success rate of IUD removal, and the pain degree of patients is lower,it is worthy of extensive promotion.

Key words： Nilestriol Misoprostol Postmenopausal women Intrauterine device Application effect

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HE Ying. Application of Nilestriol combined with Misoprostol in removal of intrauterine device for postmenopausal women[J]. 中国当代医药, 2017, 24(1): 113-115.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I1/113

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