中国当代医药

中国当代医药

Home

中文

中国当代医药

Forthcoming Articles

Advanced Search

Download Articles

Quick Search


2017 Vol. 24, No. 7 Published: 2017-03-08

	4	Meta analysis of clinical outcomes in patients with type 2 diabetes undergoing coronary artery bypass grafting
		WU Zhi-guo;LIN Li-chang;TAN Jian;PENG Hong
		Objective To investigate the mortality(30 days,1 year,3,5,10 years)and relative risk(RR)of patients undergoing coronary artery bypass grafting(CABG)for diabetics mellitus(DM)and non-diabetics mellitus(NDM).Methods By refering to relevant DM guidelines for inclusion criteria and exclusion criteria,search strategies were made out.Afterwards,Pubmed, EMBase,Cochrane library,SinoMed,CNKI,WanFang&VIP databases were searched for literatures published from January 1981 to December 2016.Subsequently,Meta analysis was used to investigate the mortality and relative risk(RR)of patients with DM and NDM after 30 days,1 year,3,5,10 years.A quality assessment scale was developed to identify each potentially qualified document,moderate and high quality documents were selected for data extraction&meta-analysis.RevMan5.3 software was used for statistical analysis.Results 28 eligible documents were identified for pooled analysis.The pooling mortality of 30 days,1 year,3,5,10 years for DM group and NDM group was 2.65%,1.92%;5.21%,3.23%;10.15%,5.86%;16.88%, 11.20%;23.12%,21.40%.The pooled RR(95%CI)for mortality rate of DM group versus NDM group were significantly increased at 30 days[1.50(1.34,1.68)],1 year[1.88(1.59,2.22)],3 years[1.74(1.53,1.99)]and 5 years[1.52(1.34,1.73)]after CABG(P＜0.01). 10 years mortality was failed to make pooled analysis due to obvious heterogeneity(I2＞70%).Conclusion The pooling data indicates that CABG may considerably increase mortality risk of 30 days,1 year,3,5,10 years in DM compared to NDM.
		2017 Vol. 24 (7): 4-10转15 [Abstract] ( 161 ) HTML (67 KB) PDF (0 KB) ( 33 )

	11	Analysis on secretion levels of long-term vaccine activation of Th1/Th2 cytokine after new influenza A(H1N1)vaccination in children
		XIA Hong-bo;CHEN Jun-ru;GUO Jin-jin;TANG Yan-li;SUN Wan-bang
		Objective To test the changes of secretion levels of long-term vaccine activation of Th1/Th2 cytokine after new influenza A(H1N1)vaccination in children.Methods A total of 31 healthy children who were on their own willing for new influenza A(H1N1)vaccination from December 2009 to January 2010 in our hospital were selected,lymphocyte cells were separated from 3 ml peripheral blood for culture,and then were divided into new influenza A(H1N1)stimulation group(the experimental group)and normal cell group(the control group).The levels of Th cytokine secretion were measured by flow CBA and enzyme-linked immunosorbent assay(ELISA).Results The technical examination of the flow CBA showed that the levels of TNF-α and IL-10 in the experimental group was significantly lower than those in the control group,with significant difference(P＜0.05).The ELISA method displayed no significant difference in the level of TNF-α and IL-4 between the experimental group and the control group(P＞0.05).The level of IL-10 in the experimental group was significantly lower than that in the control group,which was in statistical differences(P＜0.05).The levels of IL-10 in both the control group and the experimental group tested by flow CBA was significantly higher than those by the ELISA test, with statistical differences(P＜0.05).The correlation of test outcomes by the two methods was displayed a statistical significance in equation of Y=206.59+0.082X and Y=136.70+0.168X respectively.Conclusion Re-stimulation of new influenza A H1N1 vaccine cannot activate Th1 and Th2 cells in a great success,that′s to say,no satisfactory Th1 cellular immune response and humoral immunity suggesting that the specific immune memory function of the new influenza AH1N1 is poor.The higher sensitivity and the same test results are obtained by flow CBA and the traditional ELISA method in detecting cytokines.
		2017 Vol. 24 (7): 11-15 [Abstract] ( 168 ) HTML (53 KB) PDF (0 KB) ( 34 )

	16	Application value of DWI in the preoperative assessment and the evaluation of efficacy of radiochemotherapy for rectal cancer
		ZHAO Jin;QIAN Li-xia
		Rectal cancer is the third most common malignancy in all the world which seriously affects human physical health and quality of life.It should be valued by people,and the realization of individualized treatment strategies is very important.MRI and its functional MR can be used to diagnose rectal cancer accurately,and assess preoperative situation, predict prognosis and evaluate effect of radiotherapy and chemotherapy which provide useful informations for choosing clinical treatment strategies.In this article,we reviewed the clinical application of DWI in preoperative evaluation of rectal cancer and evaluation of radiotherapy and chemotherapy.
		2017 Vol. 24 (7): 16-18 [Abstract] ( 133 ) HTML (37 KB) PDF (0 KB) ( 32 )

	19	Advances in the application of elevated cardiac troponin in patients with chronic kidney disease
		DOU Li-na;JIANG Hong-ying
		Cardiac troponin(cTn)can be increased at the time of myocardial necrosis,which,as is universally known,it is a marker for diagnosis of myocardial injury,especially in the diagnosis of acute coronary syndrome(ACS)that have been recognized by at home and abroad.However,the increase of cTn is also seen in non-coronary heart diseases(myocarditis,arrhythmia,heart failure)and non-heart diseases(chronic kidney disease,sepsis,stroke etc.).In recent years,it has no longer been something unusual that significantly higher serum cTn is detected in patients with chronic kidney disease (CKD)than that of non-CKD patients.As for the reason,on the one hand,the elevated levels of cTn is subject to kidney diseases,such as decreased renal clearance rate;on the other hand,CKD complicated with cardiovascular diseases(CVD) eventually leads to the rise of cTn levels.In this paper,the causes and mechanisms of elevated cTn in non-dialysis CKD, the relationship between cTn and kidney diseases as well as its role in prediction of CVD with ACS are mainly discussed.
		2017 Vol. 24 (7): 19-22 [Abstract] ( 126 ) HTML (47 KB) PDF (0 KB) ( 29 )

	23	Clinical effect observation of alveolar lavage used by fiberoptic bronchoscopy in the treatment of bronchiectasis complicated with infection
		YU Yan
		Objective To investigate the clinical effect of alveolar lavage used by fiberoptic bronchoscopy in the treatment of bronchiectasis complicated with infection.Methods 120 cases with bronchiectasis complicated with infection treated in our hospital from August 2014 to October 2016 period were selected and they were divided into two groups according to the two-color ball grouping,and each group had 60 cases.Control group was given routine suctioning treatment,while observation group was given alveolar lavage used by fiberoptic bronchoscopy treatment.After treatment,the therapeutic effect,recovery time,length of hospital stay,number of revisits and complications were compared between two groups.Results After treatment,the total effective rate was 95.00%in observation group and 83.33%in control group, and there was a significant difference between two groups(P＜0.01).The recovery time,length of hospital stay in observation group were significantly shorter than those of control group,and number of re-treatment was significantly lower than that of control group(P＜0.01).The incidence rate of complication in observation group was 3.33%,which was lower than the controlgroup(11.67%),and the difference was statistically significant(P＜0.05).Conclusion Alveolar lavage used by fiberoptic bronchoscopy in the treatment of bronchiectasis complicated with infection has a better effect,and can improve the clinical symptoms of patients with fewer complications,it is worthy of promotion.
		2017 Vol. 24 (7): 23-25 [Abstract] ( 193 ) HTML (36 KB) PDF (0 KB) ( 35 )

	26	Influence of flat nail groove plasty for degree of healing and appearance satisfaction in the onychocryptosis type paronychia
		WEN He-long;HUANG Jin-he;ZHANG Geng-ming
		Objective To explore the clinical effects of flat nail groove plasty in the treatment of onychocryptosis type paronychia.Methods 82 cases of onychocryptosis type paronychia and who accepted treatments in our hospital from January to November in 2015 were selected as the research objects,and were divided into the control group and the observation group by the random digit table method,with 41 patients in each group.The observation group was treated with flat nail groove plasty,while the control group was treated with total nail extraction.Then,the degree of wound healing, the degree of satisfaction and the recovery condition of the two groups were compared.Results The degree of postopera tive incision healing in the observation group was better than that in the control group,with significant difference(P＜0.05). The postoperative appearance satisfaction rate of the observation group was 95.12%,which was higher than that in the control group(75.61%),with significant difference(P＜0.05).The healing time in the observation group was shorter than that in the control group,the number of dressing change in the observation group was less than that in the control group,with significant difference(P＜0.01).The recurrence rate in the observation group was 4.88%,there was no deformity;while the recurrence rate in the control group was 26.83%,and the incidence of malformation was 12.20%;there was significant difference between the two groups(P＜0.05).Conclusion The flat nail groove plasty in the treatment of onychocryptosis type paronychia is feasible,which is beneficial to the wound healing,the incision is beautiful,and it can also reduce the recurrence rate and the incidence of deformity,thus it has certain promotion value.
		2017 Vol. 24 (7): 26-28 [Abstract] ( 156 ) HTML (38 KB) PDF (0 KB) ( 37 )

	29	Clinical observation of Palmer Fu Lin Capsules combined with Methotrexate in the treatment of Sjögren syndrome
		CHEN Cheng;YANG Zhi;CAI Yue-ming
		Objective To explore clinical effect of Palmer Fu Lin Capsules combined with Methotrexate in the treatment of Sjögren syndrome(SS).Methods 100 patients with SS were selected as the research object in the Shenzhen Hospital of Peking University from February 2014 to May 2016 and divided into control group and combined treatment group according to treatment measures,50 cases in each group.The control group were treated with methotrexate 2.5 mg/tablet, each time 4 tablets,1 time a week;the combined treatment group were treated with Palmer Fu Lin Capsules each time 2 tablets,2 times/d on the basis of the control group,patients of two groups were treated for 6 months.Rheumatoid factor (RF),ESR,C reactive protein(CRP),salivary flow rate,Schirmer test,serum γ-globulin,blood coagulation index level before and after treatment,and clinical curative effect were compared between two groups.Results RF,ESR,CRP,saliva flow rate,Schirmer test,serum γ-globulin,activated partial thromboplastin time(APTT),prothrombin time(PT),fibrinogen (FIB),thrombin time(TT),D-Dimer(D-D)between two groups before treatment had no difference(P＞0.05).APTT,PT,TT in two groups before and after treatment had no difference(P＞0.05);RF,ESR,CRP,saliva flow rate,Schirmer test,serum γglobulin,FIB,D-D after treatment in two groups was lower than that before treatment(P＜0.05).RF,ESR,CRP,saliva flow rate,Schirmer test,serum γ-globulin,FIB,D-D of the combined treatment group was lower than that of the control group (P＜0.05).The total effective rate of the combined treatment group was higher than that of the control group,the difference was statistical significance(P＜0.05).Conclusion Clinical symptoms of Palmer Fu Lin Capsules combined with Methotrexate in the treatment of(SS)improve obviously,clinical effect is good,it is worthy of clinical application.
		2017 Vol. 24 (7): 29-31转34 [Abstract] ( 133 ) HTML (48 KB) PDF (0 KB) ( 33 )

	32	Analysis of effect of gold micro needle treating osmidrosis
		XIAO Jun-jian
		Objective To investigate the effect of gold micro needle treating osmidrosis.Methods The clinical data of 68 patients treated by micro gold needle(observation group)and 52 patients treated by minimally invasive surgery(the control group)from september 2015 to september 2016 were analyzed retrospectively.The therapeutic effect and the incidence rate of adverse reaction between two groups were compared.Results The rate of observation group was significantly higher than that of control group(97.06%vs.69.23%,P＜0.01).There was no upper limb dysfunction or other symptoms in the two groups.The incidence rate of adverse reaction in the observation group was significantly lower than that of the control group(0 vs.9.61%,P＜0.01).Conclusion The gold micro needle is a safe and effective treatment method of osmidrosis.
		2017 Vol. 24 (7): 32-34 [Abstract] ( 181 ) HTML (30 KB) PDF (0 KB) ( 45 )

	35	Effect analysis of closed drainage combined with pleurodesis and closed drainage alone in the treatment of spontaneous pneumothorax
		PANG Peng;ZHENG Xiang;LI De-yin;WANG Hui;WEN Zuo-chuan
		Objective To explore the effect of closed drainage combined with pleurodesis and closed drainage alone in the treatment of spontaneous pneumothorax.Methods 76 patients with spontaneous pneumothorax treated in our hospital from February 2014 to April 2016 were selected as research object.According to the different therapeutic measures,they were evenly divided into lonely group(closed drainage alone for treatment)and combined group(closed drainage combined with pleurodesis).The postoperative leakage time,postoperative drainage volume,postoperative catheterization time, hospital stay after surgery,clinical efficacy,recurrence rate,postoperative pain and complications were observed between two groups.Results In the combined group,the postoperative leakage time,postoperative catheterization time,and hospital stay after surgery was(43.6±4.2)min,(4.1±0.6)d,and(5.0±0.8)d,which was shorter than that in the lonely group,with(52.9± 4.8)min,(7.5±1.1)d,and(5.9±1.0)d in turn.The postoperative drainage volume in the combined group was(192.4±9.0)ml, more than that in the lonely group of(180.2±8.7)ml.The total clinical therapeutic effective rate was 94.7%,more than that of the lonely group(73.7%).The recurrence rate and incidence of complications in the combined group were both 5.3%,while in the lonely group,they were both 26.3%,the indexes in the former group were lower.The postoperative pain in the combined group was superior to that in the lonely group.All these mentioned above were displayed statistical significance after comparisons(P＜0.05).Conclusion Combination of closed drainage and pleurodesis in the treatment of spontaneous pneumothorax patients has advantages of great effect on drainage,fast recovery,and favorable prognosis,which is worthy of clinical application and promotion.
		2017 Vol. 24 (7): 35-37 [Abstract] ( 153 ) HTML (40 KB) PDF (0 KB) ( 32 )

	38	Effect of thick tube thoracic close drainage assisted by thin tube after VATS lobectomy
		XU Guang
		Objective To explore the effect of thick tube thoracic close drainage assisted by thin tube after video-assisted thoracic surgery(VATS)lobectomy.Methods From August 2009 to August 2016,78 patients with non-small cell lung cancer after VATS lobectomy in our hospital were divided into observation group(n=40,adopting thick tube thoracic close drainage assisted by thin tube)and control group(n=38,adopting conventional improved thoracic close drainage)according to the different methods of closed thoracic drainage.Perioperative condition(operation time,blood loss,number of cleaning lymph node,time of getting out of bed,length of hospitalization,time of remaining the catheter,volume of drainage,drainage effect,VAS pain score),complications rate and patients′satisfaction were compared between two groups.Results Operation time,blood loss,number of cleaning lymph node,time of remaining the catheter and total volume of drainage between two groups had no statistical differences(P＞0.05).Time of getting out of bed and length of hospitalization in the observation group was shorter than that in the control group(P＜0.05).Drainage effect and patients′satisfaction was significantly higher than that in the control group(P＜0.05),the complication rate and VAS pain score was significantly lower than that in the control group(P＜0.05).Conclusion The thoracic close drainage assisted by thin tube has more accurate curative effect,faster recovery,less pain and complications,higher patients′satisfaction,which is worth to be promoted.
		2017 Vol. 24 (7): 38-40 [Abstract] ( 135 ) HTML (41 KB) PDF (0 KB) ( 29 )

	41	Effect of preoperative respiratory function training on the function recovery after thoracic surgery
		YANG Zhi-xiang;CHENG Wan-hong;WANG Yan-jun
		Objective To explore the impact of preoperative respiratory function training on recovery of pulmonary function after thoracic surgery.Methods 120 patients with operation in department of thoracic surgery from March 2015 to May 2016 in our hospital were selected and randomly divided into study group and control group,60 cases in each group.Before operation,the control group was used routine cough training and the study group was used abdominal breathing training,effective cough training and pursed lip training.Before and after operation,lung function of patients in two groups were recorded.The respiratory function training on improvement of patients in department of thoracic surgery were compared and observed according to pulmonary function index.Results Suction frequency of study group was less than that of control group,and the first second time vital capacity,pulse oxygen saturation,oxygen saturation,per minute maximal ventilation were obvious higher than those of control group,with the difference was significant(P＜0.05).Pulmonary function recovery satisfaction of study group at discharge time was 93.33%,higher than that of 80.00%in control group,and the difference was significant(P＜0.05).Before operation,per minute maximal ventilation,pulse oxygen saturation,oxygen saturation,the first second time vital capacity in study group was similar to that of the postoperative,the difference had no siginificance(P＞0.05).Conclusion Preoperative respiratory function training is helpful to postoperative pulmonary function recovery,which can improve the tolerance to operation,reduce postoperative respiratory complications,be conductive to the rehabilitation of patients and be worth spreading.
		2017 Vol. 24 (7): 41-43 [Abstract] ( 181 ) HTML (36 KB) PDF (0 KB) ( 41 )

	44	Clinical effect of Trimetazidine combined with Tongxinluo Capsules in treatment of coronary heart disease complicated with chronic heart failure
		ZHANG Xiang-Su
		Objective To observe the clinical effect of Trimetazidine combined with Tongxinluo Capsules in treatment of coronary heart disease complicated with chronic heart failure(CHF).Methods 104 patients with coronary heart disease complicated with CHF treated by our hospital from June 2013 to June 2016 were selected and they were randomly divided into two groups,each group had 52 cases.The control group was treated with routine treatment of coronary heart disease,regular anti-heart failure treatment and oral Trimetazidine treatment.The treatment group was treated with Tongxinluo capsules on the basis of the control group.The treatment of two groups lasted for 6 months.The improvement in cardiac function,left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD),left ventricular ejection fraction(LVEF),heart rate(HR),systolic blood pressure(SBP),6 minutes walking distance before and after treatment and the incidence rate of adverse reaction in two groups were observed,and the change in hematuria routine,liver and kidney hematuria function and electrolyte index were monitored.Results The total effective rate for the improvement in cardiac function in the treatment group(94.23%)was higher than that of the control group(78.85%), and the difference between the two groups was statistically significant(P＜0.05).LVEDD,LVESD,LVEF,HR,SBP and 6 minutes walking distance of two groups after treatment were improved compared with before treatment,before and after treatment were statistically significant(P＜0.05),and the improvement of treatment group was more obvious,compared with the control group,and the differences between the two groups were statistically significant(P＜0.05).No significant adverse reactions were observed in both groups.Conclusion Trimetazidine combined with Tongxinluo Capsules in the treatment of coronary heart disease complicated with CHF is safe and effective.
		2017 Vol. 24 (7): 44-46 [Abstract] ( 157 ) HTML (40 KB) PDF (0 KB) ( 36 )

	47	Clinical features and prognosis of the patients with acute myocardial infarction complicated with gastrointestinal bleeding
		YANG Ming-yu
		Objective To explore the clinical features and prognosis of patients with acute myocardial infarction(AMI) complicated with gastrointestinal bleeding.Methods 193 patients treated in our department of cardiology from April 2012 to April 2014 were selected as research objects.According to the disease types,the patients were divided into three groups∶group A(AMI without gastrointestinal bleeding),totally 100 cases,group B(gastrointestinal bleeding following AMI),totally 52 cases,group C(AMI following gastrointestinal bleeding)for after patients,totally 41 cases.The difference of biochemical indexes and clinical tmeament among three groups were observed.After two-years follow-up,the recurrence (including angina pectoris,heart failure,nonfatal AMI,etc.)and mortality of the three groups were compared.Results The biochemical indicators and clinical treatment of patients in three groups differed greatly from each other;glomerular filtration rates of group B and C were significantly lower than that of group A,and activated partial thromboplastin time (APTT)of group B and C was longer than that of group A,and hemoglobin of group B and C was lower than that of group A,and these differences were statistically significant(P＜0.05).The use of anticoagulant drug in three groups such as Aspirin and Clopidogrel were differed from each other,and differences were statistically significant(P＜0.05).Although patients in group B and C both were with gastrointestinal bleeding,patients in group B needed less blood transfusion than that in group C,and difference was statistically significant(P＜0.05).After two-years follow-up,the recurrence of circulatory dysfunction diseases and mortality of group B and C were more than those of group A,and differences were statistically significance(P＜0.05).Conclusion AMI patients complicated with gastrointestinal bleeding have more clinical features,need more complex anticoagulant treatment,suffer more risks of recurrence,and have worse prognosis than AMI patients without gastrointestinal bleeding.
		2017 Vol. 24 (7): 47-49 [Abstract] ( 133 ) HTML (40 KB) PDF (0 KB) ( 36 )

	50	Effect analysis of Alteplase thrombolysis in the treatment of ST-segment elevation acute myocardial infarction
		ZHAO Wen-juan
		Objective To investigate effect of Alteplase thrombolysis in the treatment of ST-segment elevation acute myocardial infarction.Methods 152 patients with ST-segment elevation acute myocardial infarction treated in our hospital from October 2012 to October 2015 were selected and divided into control group and observation group by random number table method,76 cases in each group.Patients in the control group were treated with Urokinase,while patients in the observation group treated with Alteplase.Electrocardiogram was detected before and after treatment.Cardiovascular reperfusion was analyzed at different time points.Clinical efficacy and adverse reactions were compared between two groups.Results Compared with before treatment,Q wave time,Q wave/R wave,ST segment deviation after treatment was decreased in two groups(P＜0.01);Q wave time[(0.042±0.009)d],Q wave/R wave(0.31±0.06),ST segment deviation[(3.20± 0.57)mV]in the observation group was lower than that in the control group[(0.051±0.010)d,0.36±0.05,(4.35±0.61)mV] (P＜0.01).Compared at same time points in the group,cardiovascular reperfusion rate of patients with onset time≤6 h was higher than that of patients with onset time＞6 h(P＜0.05);compared at same time points between two groups,cardiovascular reperfusion rate in the observation group was higher than that in the control group(P＜0.05).Total effective rate in the observation group was higher than that in the control group(97.4%vs.82.9%)(P＜0.01).Incidence of adverse reactions in the observation group was lower than that in the control group(2.6%vs.13.2%),and the difference was statistically significant(P＜0.05).Conclusion Alteplase thrombolysis has significant effect in the treatment of ST-segment elevation acute myocardial infarction,which has high safety,which is worthy of clinical application.
		2017 Vol. 24 (7): 50-52 [Abstract] ( 120 ) HTML (40 KB) PDF (0 KB) ( 35 )

	53	Clinical study of coronary artery bypass grafting with simultaneous cardiac valve replacement in the treatment of coronary heart disease with heart valve disorder
		HUANG Zhi-hui;ZHANG Jian-bin;LIU Zhi-yuan;OU Bin;HUANG Si-na;XU Chong-fei
		Objective To analyze the clinical effect of coronary artery bypass grafting(CABG)and simultaneous cardiac valve replacement in the treatment of coronary heart disease(CHD)with heart valve disorder.Methods 32 patients with CHD with heart valve disorder admitted into our hospital from October 2010 to November 2016 received CABG and simultaneous cardiac valve replacement.There were 25 cases of mitral valve replacement and bypass,4 cases of aortic valve replacement and bypass,3 cases of mitral valve replacement,aortic valve replacement and bypass.The postoperative situation,recovery of cardiac function,incidence of complications and follow-up of all patients were analyzed.Results The postoperative ventilator time of patients was(34.59±2.85)h,ICU monitoring time was(4.74±1.62)d,hospital stays was(13.29±2.33)d.The left ventricular ejection fraction after surgery was significantly higher than that before surgery,and left ventricular end-diastolic dimension and end-systolic dimension was smaller than that before surgery (P＜0.05).There was 11 cases of postoperative complications among 32 cases of patients,and the incidence of complications was 34.38%.According to follow-up of patients,the cardiac function of all patients improved after surgery,and 29 cases(90.63%)significantly recovered,3 cases(9.38%)needed to install permanent cardiac pacemaker(1 case of installation 14 d after surgery,1 case of installation 398 d after surgery,1 case of installation 851 d after surgery),but without perivalvular leakage.Conclusion CABG and simultaneous cardiac valve replacement in treating CHD with heart valve disorder has significant clinical effects,it can effectively improve cardiac function state and has good long-term prognostic effects,which is worthy of clinical application.
		2017 Vol. 24 (7): 53-55转59 [Abstract] ( 141 ) HTML (44 KB) PDF (0 KB) ( 36 )

	56	The relationship between the distribution of red blood cell distribution width and NYHA classification and the effect of short-term prognosis in patients with chronic heart failure
		HUANG Si-shi
		Objective To study the relationship between the distribution of red blood cell distribution width(RDW)and NYHA classification and the effect of short-term prognosis in patients with CHF.Methods A total of 193 patients who were hospitalized in our hospital and diagnozed as CHF from June 2013 to June 2015.According to the NYHA divided into A group(55 cases，gradeⅠ),B group(42 cases，gradeⅡ),C group(48 cases，gradeⅢ),D group(48 cases，gradeⅣ).Cox regression analysis was used to analyze the risk factors of death in patients with CHF.Results Hemoglobin(Hb) and red blood cell(RBC)decreased with the increase of NYHA grade;Hb and RBC of group A,group B,group C,group D were decreased,the difference was statistically significant(F1=4.044,F2=2.906,P＜0.05);LgNT-proBNP of group A,group B, group C,group D were increased,the difference was statistically significant(F=3.492,P＜0.01);Cox forward stepwise regression analysis showed that RDW,Hb,N-terminal B-type natriuretic peptide(LgNT-proBNP)and age were independent predictors of poor prognosis in patients with CHF(HR=1.892,3.924,0.925,1.003,P＜0.05).Conclusion Compared with age and Hb factor,RDW level has a better independent predictive value for the NYHA classification of CHF patients.
		2017 Vol. 24 (7): 56-59 [Abstract] ( 173 ) HTML (35 KB) PDF (0 KB) ( 33 )

	60	Effects of thrombus aspiration associated with Nicorandil in coronary on no-reflow of acute myocardial infarction after emergency PCI
		WU Jun;DENG GEN-qun
		Objective To investigate the effect and security of thrombus aspiration associated with Nicorandil in coronary on no-reflow of acute myocardial infarction after emergency percutaneous coronary intervention(PCI).Methods 120 patients in our hospital from December 2014 to December 2015,with emergency PCI for ST elevation myocardial infarction,preoperative infarction related artery(IRA)thrombolysis in myocardial infarction(TIMI)≤grade 1,were randomly divided into nicorandil group and control group according to the medical record number,each group had 60 patients.Two group did the same operation.When no-reflow after PCI appeared,intracoronary Nicorandil or Nitroglycerin was administered in each group separately.At the end of PCI,TIMI grade and TIMI myocardial perfusion grade(TMPG) were observed in the two groups,ST-segment down of ECG and the incidence of major adverse cardiac events(MACE)during hospitalization were compared between two groups.Results The proportion of with TIMI grade and TMPG grade of the nicorandil group was significantly better than that of the control group(P＜0.05).The incidence rate of ST-segment down of the nicorandil group was significantly higher than that of the control group(P＜0.05).The incidence rate of MACE in the nicorandil group was significantly lower than that in the control group before discharge(P＜0.05).Conclusion The therapy of thrombus aspiration associated with Nicorandil in coronary for no-reflow of acute myocardial infarction after emergency PCI can improve coronary blood flow and myocardial reperfusion in infarct area,improve shortterm prognosis and is safe and effective.
		2017 Vol. 24 (7): 60-63 [Abstract] ( 171 ) HTML (46 KB) PDF (0 KB) ( 30 )

	64	Clinical effect of traditional Chinese medicine combined with Western medicine in the treatment of senile patients with frequent transient ischemic attack and its influence on hemorheology
		ZHANG Yan-ying;SHI Zhen-dong
		Objective To explore the clinical effect and the influence on hemorheology of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with conventional Western medicine in the trentment of senile patients with frequent transient ischemic attack(TIA).Methods According to random number table method,126 elderly patients with frequently TIA from February 2013 to February 2016 treated in our hospital were randomly divided into the observation group and the control group,each group had 63 patients.The observation group was treated with Salviae Miltiorrhizae and Ligustrazine Hydrochloride injection drip,the control group was treated with Dextran 40 Sodium Chloride Injection for intravenous drip,trentment course lasted for 2 weeks.At the same time,the two groups was treated with conventional drug therapy,including Aspirin,Clopidogrel and Atorvastatin,etc.The clinical effect,hemorheology indexes and adverse reactions were compared between the two groups.Results The total effective of the observation group(96.8%) was obviously higher than that of control group(82.5%)(P＜0.05).In the observation group,the plasma viscosity,the whole blood high and low-shear viscosities after treatment were decreased while the control group did not change significantly,and the differences was statistically significant between two groups(P＜0.05).Both groups had no serious adverse reactions.Conclusion Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection combined with conventional Western medicine in the trentment of senile patients with frequent TIA is safe and effective,which can improve blood rheology, and without obvious adverse reaction.
		2017 Vol. 24 (7): 64-66转96 [Abstract] ( 177 ) HTML (49 KB) PDF (0 KB) ( 32 )

	67	Study on the therapeutic effect of early neurological rehabilitation in patients with cerebral infarction in acute period
		HUANG Yuan-qiu
		Objective To observe the therapeutic effect of early neurological rehabilitation in patients with cerebral infarction in acute period.Methods 80 patients with cerebral infarction in acute period who were admitted to the hospital from January to December 2015 were selected and divided into control group(n=40)and study group(n=40)according to the treatment plan.Control group was administered with drug treatment,while study group was given early neurological rehabilitation treatment on the basis of control group.Treatment effect of two groups were compared.Results The post-treatment Modified Edinburgh-Scandinavia Stroke Scale(MESSS),Barthel Index(BI)and Fugl-Meyer Assessment (FMA)score of study group were significantly better than those of control group,with statistically significant differences (P＜0.05).The therapeutical effective rate of patients in study group(95.0%)was significantly higher than that of control group(72.5%),with statistically significant difference(P＜0.05).The satisfaction degree of patients in study group(97.5%) was significantly higher than that of control group(67.5%),with statistically significant difference(P＜0.05).Conclusion Early neurological rehabilitation treatment is beneficial to improve the treatment effect of patients with acute cerebral infarction and has high treatment safety,which can promote the early recovery of patients and should be further popularized and applied in clinic.
		2017 Vol. 24 (7): 67-69 [Abstract] ( 166 ) HTML (39 KB) PDF (0 KB) ( 35 )

	70	Clinical practice and evaluation of Lamotrigine combined with low-dose Valproic Acid treating epilepsy
		LUO Chuan
		Objective To research the feasibility of Lamotrigine combined with low-dose Valproic Acid treating epilepsy. Methods A total of 62 patients with epilepsy who were treated in our hospital from March 2015 to March 2016 were enrolled in and randomly divided into observation group and control group,with 31 patients in each group.The observation group was treated with Lamotrigine combined with Valproic Acid,while the control group was treated with Valproic Acid.The clinical effect,epilepsy seizure and incidence of adverse reaction of patients between two groups were compared.The correlation of blood concentration of Lamotrigine and Valproic Acid in observation group were analyzed. Results The total effective rate of observation group(93.55%)was significantly higher than that of control group(74.19%) (P＜0.05).The number of seizures,duration time,epileptic discharge and the number of lead involved of the two groups were all significantly lower after treatment(P＜0.01)and the related indicators in observation group were all significantly lower than those in control group(P＜0.01).The correlations of blood concentration between Lamotrigine and Valproic Acid in observation group was positive(r=0.952,P＜0.05).There was no statistical difference of incience rate of adverse reaction between two groups(P＞0.05).Conclusion Lamotrigine combined with Valproic Acid can control seizure and significantly improve the clinical effect treating epilepsy.
		2017 Vol. 24 (7): 70-72 [Abstract] ( 137 ) HTML (38 KB) PDF (0 KB) ( 47 )

	73	Comparative analysis of retroperitoneal laparoscope and open surgery in the treatment of ureteral calculi
		WEI Xing-cong;WEI Wei;TANG Song-lin;HE Chao-xiong;WU Guan-ke;CHEN Hao-bin
		Objective To compare the efficacy of laparoscopic ureterolithotomy and open surgery in the treatment of ureteral calculi.Methods 51 patients with ureteral calculi who were given surgical treatment in our hospital from January 2011 to October 2016 were collected and screened.They were divided into the observation group(27 cases)and the control group(24 cases)according to the surgical procedures.The observation group was given retroperitoneal laparoscopic ureterolithotomy,and the control group was given open ureterolithotomy.The therapeutic effects of the two groups was compared.Results The amount of intraoperative bleeding in the observation group was less than that in the control group,the recovery time of gastrointestinal function,ambulation time,postoperative hospital stay in the observation group was shorter than that in the control group,with significant difference(P＜0.05).The operation time of the observation group was longer than that of the control group,with significant difference(P＜0.05).There was no significant difference between the two groups in the indwelling time of drainage tube(P＞0.05).Conclusion The clinical effect of retroperitoneal laparoscope in the treatment of ureteral calculi is obvious,the trauma is small,and the postoperative recovery is fast,which is suitable for clinical promotion.
		2017 Vol. 24 (7): 73-75 [Abstract] ( 172 ) HTML (39 KB) PDF (0 KB) ( 39 )

	76	Analysis of the effect and mechanism of action of Astragalus Injection combined with Irbesartan in the treatment of hypertensive nephropathy
		GUO Jia-yin1PEI Ke;ZHU Jing-jing;XIE Qi-lian;GUO Zhi-ling
		Objective To explore the clinical effect and its mechanism of Astragalus Injection combined with Irbesartan in the treatment of hypertensive nephropathy.Methods 94 cases of hypertensive nephropathy and who treated in our hospital from August 2014 to November 2015 were selected,and were divided into the combination group and the control group according to the different treatment methods,47 cases in each group.The control group was treated with Irbesartan alone,while the combination group was treated with Astragalus Injection combined with Irbesartan.Then,after treatment for one month,the changes of blood pressure,renal function,urinary protein of the two groups were compared. Results Diastolic blood pressure and systolic blood pressure after treatment in the two groups was lower than that before treatment,diastolic blood pressure and systolic blood pressure after treatment in the combination group was lower than that in the control group after treatment,with significant difference(P＜0.01).The level of serum cystatin C,SCr,BUN, NAG,α1-MG,24 h urinary protein quantitation after treatment in the two groups was lower than that before treatment, with significant difference(P＜0.05).The level of serum cystatin C,SCr,BUN,NAG,α1-MG,24 h urinary protein quantitation after treatment in the combination group was lower than that in the control group after treatment,with significant difference(P＜0.01).Conclusion The clinical effects of Astragalus Injection combined with Irbesartan in the treatment of hypertensive nephropathy is significant,which the renal function of the patients are restored,and the safety is high.
		2017 Vol. 24 (7): 76-78 [Abstract] ( 179 ) HTML (39 KB) PDF (0 KB) ( 41 )

	79	Correlation analysis between insulin resistance and cardiovascular disease in patients with uremia
		MIAO XuMO;Dong-mei;LIU-FU Jing-zhang;CHEN Hai-jin
		Objective To study the relationship between insulin resistance(IR)and cardiovascular disease in patients with uremia.Methods 60 uremic patients in our hospital from August 2014 to August 2016 were selected as the uremia group,and the same period of the same period,45 healthy persons were selected as the control group.The level of HOMA-IR,renal function,cardiac function,inflammatory factors and oxidative stress were compared,and the correlation between HOMA-IR and each index was analyzed.Results The level of HOMA-IR in the uremia group was lower than that in the control group,with significant difference(P＜0.05).HOMA-IR was positively correlated with LVEF and S(r= 0.507,0.618,P＜0.05),and was negatively correlated with LVESD,TC,TG,LDL-C(r=-0.386,-0.458,-0.797,-0.683,P＜0.05). Inflammatory factors and oxidative stress in the uremia group was higher than that in the control group,with significant difference(P＜0.05).HOMA-IR was negatively correlated with the levels of MDA,T-AOC,SOD,AOPP,hs-CRP,IL-6,IL-8, TNF-α(r=-0.783,-0.317,-0.896,-0.453,-0.367,-0.474,-0.526,-0.602,P＜0.05).Conclusion There is a close correlation between the occurrence of cardiovascular disease and IR in patients with uremia,and it has a certain clinical value to assess the patient′s condition and prognosis.
		2017 Vol. 24 (7): 79-81 [Abstract] ( 133 ) HTML (36 KB) PDF (0 KB) ( 40 )

	82	Effect of angiotensin converting inhibitor assist hormone in the treatment of primary nephrotic syndrome
		ZHANG Feng-xia;XU Rui-quan;TANG Xian-hu;LI Xiao-sheng;WANG Run-xiu
		Objective To investigate the effect of angiotensin converting inhibitor assist hormone in the treatment of primary nephrotic syndrome.Methods 60 primary nephrotic syndrome patients treated in our hospital from November 2013 to November 2015 were selected as study objects.All patients were divided into the control group and the experimental group according to the random number table method,and each group was 30 cases.The control group was treated with hormone and the experimental group was treated with angiotensin converting inhibitor assist hormone.The treatment effect of the two groups was compared.Results The total effective rate in the experimental group was 83.33%,which was higher than that in control group(50.00%),with significant difference(P＜0.05).The level of 24 h urinary protein,urea nitrogen,serum creatinine after treatment in the two groups was lower than that before treatment,the level of plasma albumin after treatment in the two groups was higher than that before treatment,with significant difference(P＜0.05).The level of 24 h urinary protein,urea nitrogen,serum creatinine after treatment in the experimental group was lower than that in the control group after treatment,the level of plasma albumin after treatment in the experimental group was higher than that in the control group after treatment,with significant difference(P＜0.05).The total incidence rate of adverse reaction in the experimental group was 3.33%,which was lower than that in the control group(16.67%),with significant difference(P＜0.05).Conclusion The effect of angiotensin converting enzyme inhibitors in the treatment of primary nephrotic syndrome is better.
		2017 Vol. 24 (7): 82-84 [Abstract] ( 136 ) HTML (37 KB) PDF (0 KB) ( 31 )

	85	Effect comparsi on of microscopy and retroperitoneal high ligation of spermatic vein type in treating varicocele
		HUANG Duo-bin;XIAN Jie;WANG Jun-yong;XIE Zong-bing
		Objective To compare the effect of microscopy and retroperitoneal high ligation of spermatic vein type in treating varicocele.Methods 86 varicocele patients who needed oparation in our hospital from January 2014 to January 2016 were selected and divided into the experimental group and the control group by using random number table method,43 cases in each group.The control group was used retroperitoneal high ligation of spermatic vein and the experimental group was used microsurgical technique inguinal vein ligation of spermatic vein.All patients were followed up for 6 months.The operation time,hospitalization time,symptom improvement,the incidence rate of complication and semen quality were compared.Results There was no significant difference in the operation time between the two groups (P＞0.05).The hospitalization time of the experimental group was significantly lower than that of the control group,and the difference was statistically significant(P＜0.05).The improvement of symptoms in the experimental group was significantly better than that in the control group,the incidence rate of complications in the experimental group was lower than that in the control group,and the semen quality in the experimental group was significantly better than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Microsurgical technique in treating varicocele can shorten hospitalization time,with less complications,which can effectively improve symptoms,obviously improve semen quality,it is worth to popularize.
		2017 Vol. 24 (7): 85-87 [Abstract] ( 97 ) HTML (42 KB) PDF (0 KB) ( 41 )

	88	Effect of ureteroscopy in acute obstructive renal failure
		DENG Yue-yun;LI Xiu-ning
		Objective To investigate the effect of ureteroscopy in the treatment of acute renal failure caused by upper urinary tract obstruction.Methods 47 cases with acute obstructive renal failure who underwent ureteroscopy from April 2013 to May 2016 were collected from Yunfu People′s Hospital.All the different time points before and after surgery in patients with renal function indexes of urea nitrogen,creatinine were compared,and treatment effect was evaluated.Results All patients were successfully completed the ureteroscopy operation,urea nitrogen and creatinine were decreased in varying degrees after operation,creatinine was decreased to normal at 3 d after operation in 6 patients,and 26 patients were fell to normal at 7 d after operation.Followed up for 6 months,the urea nitrogen and creatinine of 32 patients were decreased to normal,no one with complication like ureteral perforation,fracture,avulsionafter operation.Urea nitrogen and creatinine were decreased gradually after ureteroscopy operation,with significant differences(P＜0.01).Conclusion Ureteroscopy is safe and effective for the treatment of acute obstructive renal failure.It can quickly relieve ureteral obstruction,drain urine and protect renal function.It can be the first choice for acute renal failure caused by upper urinary tract obstruction.
		2017 Vol. 24 (7): 88-90 [Abstract] ( 128 ) HTML (38 KB) PDF (0 KB) ( 41 )

	91	Clinical study of prone position and semisupine-lithotomy position in percutaneous nephrolithotomy for obese patients
		WU Shi-jie;LIANG Zhi-qiang;MO Xun;WANG Shi-hua
		Objective To explore the clinical effects of percutaneous nephrolithotomy(PCNL)for obese patients in prone position and semisupine-lithotomy position.Methods 86 patients with renal calculi in our hospital from February 2013 to March 2016 were selected and randomly divided into semisupine-lithotomy group and prone group,43 cases in each group,they were respectively treated by percutaneous nephrolithotomy in prone and semisupine-lithotomy position.Operative time,volume of blood loss,length of postoperative hospital stay,one-time stone disposable rate and incidence of complications were statistically compared between two groups.Results Operative time,volume of blood loss and length of postoperative hospital stay in semisupine-lithotomy group were significantly less than those in prone group；one-time stone disposable rate of semisupine-lithotomy group was 90.7%,obviously higher than that of prone position group of 74.4%;the incidence of complications was 2.3%in semisupine-lithotomy group,significantly lower than that 13.9%in prone group,the differences were significant(P＜0.05).Conclusion PCNL in semisupine-lithotomy position can shorten operative time and postoperative hospital stay,reduce blood loss and postoperative complications,promote one-time stone disposable rate,which has higher value of clinical application for obese patients with renal calculi.
		2017 Vol. 24 (7): 91-93 [Abstract] ( 132 ) HTML (38 KB) PDF (0 KB) ( 40 )

	94	Analysis of the impact factor of renal damage in hypertensive patients
		QIAN Jing
		Objective To explore the impact factor of renal damage in hypertensive patients.Methods 85 renal damage patients with essential hypertension from September 2013 to September 2015 in our hospital were selected as renal damage group,85 patients with simple essential hypertension at the same term were selected as control group.Metabolic related index of patients in two groups were detected and compared.Results Single factor analysis showed that gender, age,course of disease,body mass index,pulse pressure and serum uric acid were the risk factors of renal damage in patients with hypertension(P＜0.05).The risk factors screened from univariate analysis was used as independent variables for Logistic regression analysised and showed course of disease,body mass index and pulse pressure were independent risk factors for renal damage in hypertensive patients(OR=4.518,4.371,2.405).Conclusion The degree of renal damage in patients with hypertension was related to the course of disease,body mass index and pulse pressure.Active control of weight and pulse pressure in hypertensive patients is beneficial to improve the prognosis of patients.
		2017 Vol. 24 (7): 94-96 [Abstract] ( 154 ) HTML (26 KB) PDF (0 KB) ( 33 )

	97	Application effect comparison of intramedullary nail and minimally invasive plate in the treatment of humeral shaft fracture for internal fixation
		FAN Qi-zhu;WU Ting;HUANG Jun;LI Xiu-qi
		Objective To compare the clinical efficacy of minimally invasive plating osteosynthesis and minimally intramedullary nailing in the treatment of humeral shaft fractures in order to find a safer and more effective therapeutic approach.Methods The clinical data of 72 patients with humeral shaft fractures from May 2013 to June 2015 in our hospital were retrospectively analyzed.The data were evenly divided into two groups in random.36 patients treated by minimally invasive plate for internal fixation were classified into the MIPO group,and the rest 36 patients treated by intramedullary nail were categorized into the MIN group.The operation time,intraoperative amount of bleeding,healing time of bone fracture,and occurrence of complications in the two groups were compared.Results The operation time in the MIN group was shorter than that in the MIPO group,and intraoperative amount of bleeding in the MIN group was less than that in the MIPO group,with statistical differences(P＜0.01).There were no significant difference in the healing time of bone fracture,score of shoulder and elbow joints improvement,or incidence of complications between the two groups(P＞0.05).Conclusion In the treatment of humeral shaft fractures,minimally intramedullary nailing is more efficient and can shorten the operation time,decrease the amount of bleeding,and reduce the risk of infection in comparison with those by minimally invasive plating osteosynthesis,which needs further exploration.
		2017 Vol. 24 (7): 97-99 [Abstract] ( 119 ) HTML (38 KB) PDF (0 KB) ( 32 )

	100	Clinical effect analysis of intervertebral foramen ligament lysis in the treatment of lumbar intervertebral disc herniation
		WEI Hui
		Objective To investigate the clinical effect of intervertebral foramen ligament lysis in the treatment of lumbar intervertebral disc herniation.Methods 50 cases of lumbar disc herniation treated in our hospital from January 2013 to May 2016 were selected and randomly divided into the observation group and the control group,25 cases in each group.The observation group was treated with foraminal ligament lysis treatment,the control group was given lateral recess block.Postoperative follow-up,JOA low back pain disease efficacy,VAS score and clinical efficacy in the two groups were compared.Results The JOA scores after 3 months and 6 months of in the two groups was higher than that before treatment,the VAS score was significantly lower than that before treatment,with significant difference(P＜0.05). The JOA score after 3 months and 6 months in the observation group was higher than that in the control group,with significant difference(P＜0.01).There was no significant differences in the VAS score at 3 months between the observation group and the control group(P＞0.05).The VAS score at 6 months in the observation group was lower than that in the control group,with significant difference(P＜0.01).The cure and efficiency rate of the observation group was higher than that of the control group,with significant difference(P＜0.05).Conclusion The effect of intervertebral foramen ligament lysis in the treatment of lumbar intervertebral disc herniation is obvious,and has high safety,which can be recommended in clinical practice.
		2017 Vol. 24 (7): 100-102 [Abstract] ( 132 ) HTML (37 KB) PDF (0 KB) ( 32 )

	103	Clinical effect of improved minimally invasive incision of open reduction and internal fixation with steel plate treating calcaneal fracture
		YOU Jun;CHEN Zi-hua;CHEN Wen-chao
		Objective To investigate the clinical effect of improved minimally invasive incision of open reduction and internal fixation with steel plate for calcaneal fracture.Methods 84 patients with calcaneal fracture admitted into our hospital from January 2015 to January 2016 were randomly divided into two groups,and there were 42 cases in each group.Two groups were given open reduction and internal fixation,control group was given L-shaped lateral incision and observation group was given improved minimally invasive incision.The perioperative indexes,imaging results,recovery of ankle joint,pain degree and incidence of complication between two groups were compared.Results The imaging results of two groups were similar,there was no statistical difference(P＞0.05).The perioperative indexes,recovery of ankle joint, improvement of pain degree in observation group were significantly better than those in control group(P＜0.05).The incidence rate of complication in observation group was significantly lower than that in control group(P＜0.05).Conclusion Improved minimally invasive incision of open reduction and internal fixation with steel plate treating calcaneal fracture has good efficacy,short surgery time,light trauma and less complications,which has application value.
		2017 Vol. 24 (7): 103-105转108 [Abstract] ( 112 ) HTML (43 KB) PDF (0 KB) ( 38 )

	106	Practice and evaluation of locking compression plate and external fixator in patients with distal tibial fracture
		TAN Jin-hong;LI Qiao;LU Sheng-hua;CHEN Xiang-jie;CAO Jia-hui
		Objective To study the clinical efficacy of locking compression plate and external fixator in patients with distal tibialfractures,and to explore its clinical applicability.Methods Thirty-six patients with distal tibial fractures visited department of orthopaedics in our hospital from June 2012 to June 2015 were selected as research objects.According to the principle of randomization,they were evenly divided into control group and experimental group.In the experimental group,locking compression plate for fixation was used,while in the control group,external fixator was adopted.After treatment,the healing situation,torsionangle,axial displacement and bending stress between two groups were compared.Inaddition,therapeutic total effective rate and incidence of complication between two groups were also compared. Results There was no significant difference in the twist angle between the two groups(P＞0.05).The axial displacement and bending stress in the experimental group were significantly lower than those in the control group,with statistical differences(P＜0.05).The total effective rate in the control group was 77.78%,and it was significantly lower than that in the experimental group accounting for 94.44%,which was displayed a statistical significance(χ2=4.43,P＜0.05).The incidence rate of complication in the control group was 33.33%,ans it was higher than that in the experimental group accounting for 5.56%,with a statistical difference(χ2=4.43,P＜0.05).Conclusion Compared with the external fixator,the application of locking compression plate in the treatment of distal tibial fractures can obtain a remarkable clinical efficacy in a low incidence of complications,which is worthy of clinical application and promotion.
		2017 Vol. 24 (7): 106-108 [Abstract] ( 155 ) HTML (32 KB) PDF (0 KB) ( 30 )

	109	Observation on the effect of dorsal metacarpal artery skin flap in repairing finger soft tissue defect
		YIN Shi-hai;WAN Chuan-jun;SHI Qing-mei;QI Jin-feng;HU Ming-long;SUN Min-yu
		Objective To study the method and effect of dorsal metacarpal artery skin flap in repairing finger soft tissue defects.Methods From March 2013 to March 2016,18 patients with finger soft tissue defects who were admitted to the hospital and given dorsal metacarpal artery skin flap repair were retrospectively analyzed.Results 18 cases of flap were completely survived and the wound was healed at stageⅠ;among them,distal epidermal necrosis were observed in 3 cases of flap,and was healed after dressing.The patients were followed up for 4 to 14 months，with an average of 10 months. The flap color，shape and texture were good.Temperature,touch，pain were still existed.No bloat was seen.Most of the sensory function were recovered，and the finger flexion and extension function was not affected.According to TAM method,the healthy side was evaluated accounting for 70%-85%.Two-point-discrimination reached up to 7~10 mm (average 8.5 mm)via nerve suture in the patients with the flap located at the palm side.There were 13 cases of donor site sutured directly and 5 cases of skin-graft repair,with stageⅠhealing for all.Scar hyperplasia was not obvious.The function of the injured finger was good.Conclusion The dorsal metacarpal artery skin flap is a convenient method for cutting and collecting,with reliable blood supply and undamaged main vessel,which is a favorable method for the repair of finger soft tissue defects.
		2017 Vol. 24 (7): 109-111 [Abstract] ( 126 ) HTML (36 KB) PDF (0 KB) ( 35 )

	112	Clinnal effect of the single arm adjustable bracket with Kirschner wire for minimally invasive treatment of distal tibial fractures
		ZHOU Guo-jin;ZENG You-wen;ZHONG Sheng-tao
		Objective To evaluate clinical effect of the single arm adjustable bracket with Kirschner wire for minimally invasive treatment of distal tibial fractures(DTF).Methods 94 patients with DTF treated in our hospital from September 2012 to September 2015 were divided into control group and observation group according to the different treatment methods,47 cases in each group.The control group was treated with traditional open reduction and plate fixation,the observation group was adopted minimally invasive treatment with the single arm adjustable bracket with Kirschner wire. The therapeutic effects of two groups were compared.Results The operation time,incision length,the bleeding after releasing tourniquet,hospitalization time and healing time of the observation group was significantly lower than that of the control group.The Kofoed score at 12 months after operation was significantly higher than that of the control group(P＜0.05). The Johner-Wruhs excellent rate of the observation group was significantly higher than the control group(91.49%vs. 72.34%,P＜0.05),and the complication rate was significantly lower than that of the control group(6.38%vs.23.40%,P＜0.05).Conclusion Curative effect of the single arm adjustable bracket with Kirschner wire for minimally invasive treatment of DTF is sure,with characteristic of less trauma,postoperative recovery fast,less complications,which is worthy of recommendation.
		2017 Vol. 24 (7): 112-114 [Abstract] ( 130 ) HTML (42 KB) PDF (0 KB) ( 39 )

	115	Value of serum high-sensitivity C reactive protein,immunoglobulin and Mycoplasma Pneumoniae DNA in diagnosis of children with Mycoplasma pneumonia
		GUO Rui-xue
		Objective To investigate the value of serum high-sensitivity C reactive protein(hs-CRP),immunoglobulin and Mycoplasma Pneumoniae DNA(MP-DNA)in diagnosis of children with Mycoplasma pneumonia(MPP).Methods Altogether 120 children confirmedly diagnosed with MPP who were hospitalized from January 2013 to January 2016 in department of pediatrics in our hospital were selected as MPP group;30 healthy children who were treated in department of outpatient in our hospital at the same period of time were selected as control group;the levels of serum hs-CRP,immunoglobulin(IgA,IgG,IgM etc.)and MP-DNA of the two groups were detected and compared.Results The levels of hs-CRP and MP-DNA of patients in MPP group were higher than those in control group,with statistically significant difference(P＜0.05);the levels of IgA,IgG and IgM of child patients in MPP group were lower than those in control group,with statistically significant difference(P＜0.05).The ROC curve showed the area under hs-CRP curve was 0.776,when the optimal threshold value was 8.18 mg/L,the sensitivity and specificity in diagnosis of MPP were 0.724 and 0.862;as for the combined detection of IgA+IgG+IgM,the area under curve was 0.778,the optimal threshold was 2.68 mg/L,the diagnostic sensitivity and specificity of MPP were 0.808 and 0.694;the area under the MP-DNA curve was 0.751,the optimal threshold was 7.56×105copy/mL,the diagnostic sensitivity and specificity of MPP were 0.769 and 0.781.Conclusion Combination application of hs-CRP,immunoglobulin and MP-DNA in detection of patients with MPP is of high value in early diagnosis.
		2017 Vol. 24 (7): 115-117 [Abstract] ( 137 ) HTML (34 KB) PDF (0 KB) ( 39 )

	118	Clinical effect of hysteroscopy in patients with uterine incisional diverticula after cesarean section
		ZHAN An-na;WEN Xiao-yan;QIU Yu;PENG Juan
		Objective To explore the difference of hysteroscopy and abdominal surgery in the treatment of uterine incision diverticulum after cesarean section and the clinical effect of hysteroscopy.Methods 38 patients with uterine incisional diverticulum treated in our hospital from January 2013 to August 2015 were selected and divided into hysteroscopy group(n=20)and abdominal surgery group(n=18)according to the patients′requirements.The operation data, postoperative complications,and menstrual period in 3,6,12 months after surgery in the two groups were compared.Results The time of operation and hospitalization in the hysteroscope group were shorter than those in the abdominal surgery group,the intraoperative amount of bleeding in the hysteroscopy surgery group was less than that in the abdominal surgery group,and the differences were statistically significant(P＜0.01).There was no significant difference in hospitalization expenses between two groups(P＞0.05).The incidence of postoperative complications of patients in the hysteroscopy group(15.00%)was lower than that in the abdominal surgery group(27.78%),and the difference was statistically significant(P＜0.05).The menstrual period in the hysteroscope groupin 3 months after surgery[(5.51±2.34)d]was shorter than that in the abdominal surgery group[(6.68±1.42)d]and the difference was statistically significant(P＜0.01)，but there was no significant difference between the menstrual period in two groups in 6,12 months after surgery(P＞0.05).Conclusion In the treatment of uterine incisional diverticulum,hysteroscopy is better than the abdominal surgery with regard to intra and postoperative recovery as well as occurrence of complications,which is worthy of clinical promotion.
		2017 Vol. 24 (7): 118-120 [Abstract] ( 143 ) HTML (36 KB) PDF (0 KB) ( 32 )

	121	Application effect of Mirena in patients after hysteroscopic endometrial polypectomy
		GUO Xiao-ling;LI Li-qin;GONG Cui-mei
		Objective To explore the application of Mirena in patients after hysteroscopic endometrial polypectomy. Methods 72 patients acccepted hysteroscopic endometrial polypectomy in our hospital from January 2014 to January 2015 were selected,and divided into control group and observation group according to random number table method, with 36 cases in each group.Patients in the control group were given the oral administration of Megestrol Acetate Tablets after operation,while patients in the observation group were given the Mirena after operation.The patients′operation situation,the changes of endometrial thickness immediate and 6,12 months after operation of two groups measured by B-ultrasound and hysteroscopy and the recurrence rate of endometrial polyps after 1 year follow-up of two groups were compared.Results Patients in two groups were all successfully completed surgery and there was no statistically significant difference in the amount of bleeding and operation time between two groups(P＞0.05);the thickness of endometrium 6 and 12 months after operation in the observation group was lower than those in the control group，and the differences were statistically significant(P＜0.05).The recurrence rate of endometrial polyps after 1 year of follow-up in the observation group was lower than that in the control group，and the difference was statistically significant(P＜0.01). Conclusion Mirena can effectively improve the comditional endometrial thickness and prevent the recurrence of polyps in patients with endometrial polyps after hysteroscopic resection.
		2017 Vol. 24 (7): 121-123 [Abstract] ( 155 ) HTML (36 KB) PDF (0 KB) ( 33 )

	124	Efficacy of uterine tamponade balloon catheter combined with cervical clamp in intractable postpartum hemorrhage
		GONG Xiao-bin
		Objective To explore and analyze the efficacy of uterine tamponade balloon catheter combined with cervical clamp in intractable postpartum hemorrhage.Methods 79 patients diagnosed with intractable postpartum hemorrhagein our hospital from July 2015 to June 2016 were selected and divided into the observation group(42 cases)and the control group(37cases)according to the hospital admission sequence.All patients in two groups were received uterine tamponade balloon catheter and patients in the observation group were also received cervical clamp in addition,the number of hysterectomy,hemostatic effect and amount of bleeding of patients between two groups were conpared.Results In the observation group,the incidence of hysterectomy of patients(0.00%)was lower than that in the control group(10.81%), the success rate of hemostasis(97.62%)was higher than that in the control group(83.78%);the amount of bleeding[(146.92± 13.25)ml]was less than that in the control group[(269.25±18.25)ml],and the differences were statistically significant (χ2=4.783,P=0.029;χ2=4.663,P=0.031;t=34.369,P=0.000).Conclusion The efficacy of uterine tamponade balloon catheter combined with cervical clamp in intractable postpartum hemorrhage is accurate,which can reduce the incidence of hysterectomy,increase the success rate of hemostasis and reduce intraoperative hemorrhage,and worthy of clinical promotion.
		2017 Vol. 24 (7): 124-126 [Abstract] ( 110 ) HTML (38 KB) PDF (0 KB) ( 35 )

	127	Clinical effect of Recombinant Human Interferon α-2b Gel treating chronic cervicitis combined with high-risk HPV infection
		QIU Chang-hui
		Objective To analyze the clinical effect of Recombinant Human Interferon α-2b Gel treating chronic cervicitis combined with high-risk HPV infection.Methods 99 patients with chronic cervicitis combined with high-risk HPV infection treated in our center from November 2014 to November 2015 were selected as research objects,and were divided into two groups according to the random number table.48 cases of the group A were treated with Recombinant Human Interferon α-2b Gel,and 51 cases of the group B were treated with Compound Shajiziyou Suppositories.The cervical ectropion lesion area,HPV-DNA,character and quantity of leucorrhea in the two groups was observed in the following-up.Results The lesion area of two groups was improved obviously,and the difference between two groups had no statistical significance(P＞0.05).The negative conversion ratio of HPV-DNA of group A was evidently higher than that of group B,and the difference between two groups had statistical significance(P＜0.01).The character and quantity of leucorrhea in the two groups were improved after treatment compared with before treatment,but the differences between two groups had no statistical significance(P＞0.05).Conclusion Recombinant Human Interferonα-2b treating chronic cervicitis combined with high-risk HPV infection not only has good clinical effect,but also makes the HPV conversion ratio of patients higher,which is worthy of promotion.
		2017 Vol. 24 (7): 127-129 [Abstract] ( 127 ) HTML (41 KB) PDF (0 KB) ( 39 )

	130	Clinical effect of laparoscopic prolapse of uterus rectus abdominis in treatment of uterine prolapse
		HUANG Zao-xiu;LIU Rong-xiu;YI Shu-ying
		Objective To investigate the clinical effect of laparoscopic uterine rectus abdominis prolapse fixation in the treatment of uterine prolapse.Methods 50 patients with uterine prolapse in our hospital from January 2014 to December 2015 were selected as the study objects.Patients were divided into control group and observation group according to the random number table method,with 25 cases in each group.The control group was treated with traditional vaginal hysterectomy and vaginal anterior and posterior wall repair.The operation and therapeutic effect were compared between the two groups.Results The operative time and hospital stay of the observation group were shorten than those of the control group,and the blood loss was less than that of the control group,the differences were statistically significant(P＜0.05);there was no significant difference in the postoperative pelvic organ prolapse quantification(POP-Q)and recurrence rate between the two groups(P＞0.05).Conclusion Laparoscopic prolapse of uterus rectus abdomen is effective in the treatment of uterine prolapse.The surgical procedure is simple,wilth less invasive,and lower recurrence rate.It should be popularized in clinical practice.
		2017 Vol. 24 (7): 130-132 [Abstract] ( 106 ) HTML (36 KB) PDF (0 KB) ( 38 )

	133	Feasibility analysis of Guizhi Fuling Capsules in the treatment of perimenopausal uterine fibroids
		QIU Chun-xiu
		Objective To analyze the feasibility of Guizhi Fuling Capsules in the treatment of uterine leiomyoma in perimenopausal period.Methods 387 cases of women with uterine leiomyoma in perimenopausal period treated in our hospital from January 2015 to January 2016 were randomly divided into observation group(200 cases)and control group (187 cases)according to treatment methods.Patients in the control group were treated with oral Mifepristone Tablets, 12.5 mg once,qd;patients in the observation group were given Guizhi Fuling Capsule based on the control group,4 capsules each time,tid,all patients were treated for 6 months.The therapeutic effects were compared between the two groups after treatment;the levels of estradiol(E2),hormones(P),luteinizing hormone(LH),follicle stimulating hormone(FSH)and the volume of uterine leiomyoma were measured and compared before and after treatment.Results The total effective rate of the observation group and the control group was 96.00%and 75.40%,the difference between the two groups was statistically significant(P＜0.05).After treatment,the serum levels of E2,P,LH and FSH in the two groups were significantly lower than those before treatment,and the levels of the observation group were significantly lower than those of the control group,the differences were statistically significant(P＜0.05);the volume of uterine fibroids of the two groups was significantly less than that before treatment,and the volume of uterine leiomyoma in the observation group was significantly less than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Mifepristone combined with Guizhi Fuling Capsules can effectively improve the curative effect of patients with uterine leiomyoma in perimenopausal period,suitable for clinical promotion.
		2017 Vol. 24 (7): 133-135 [Abstract] ( 127 ) HTML (39 KB) PDF (0 KB) ( 36 )

	136	Analysis of immune function status in children with refractory Mycoplasma pneumonia
		LI Shao-cun;HUANG Li-na;GUO Chu
		Objective To explore effect of immune function status on refractory Mycoplasma pneumonia in children. Methods 100 children with refractory Mycoplasma pneumonia from February 2014 to November 2016 were selected as experimental group;while 100 children with general Mycoplasma pneumonia were selected as control group.Levels of serum immunoglobulin,T lymphocyte subsets,complement and extrapulmonary manifestations of two groups were detected and compared by using flow cytometry and immunoturbidimetry.Results Levels of serum IgG,IgA,IgM in experimental group were obvious higher than control group(P＜0.05).Levels of serum CD3+,CD4+and CD4+/CD8+in the experimental group were obvious lower than control group(P＜0.05).There was no significant difference in the levels of CD8+and complement C3 and C4 between the two groups(P＞0.05).The incidence of xtrapulmonary manifestations such as cardiovascular,liver,digestive tract,skin and nervous system in experimental group was higher than that of the control group,and the difference was statistical significance(P＜0.05).Conclusion Severe immune dysfunction in children with refractory Mycoplasma pneumonia,the main features of immunoglobulin,T lymphocyte subsets and complement levels are closely related to the incidence of extrapulmonary symptoms.It is suggested that reasonable immunotherapy can help to improve the condition,relieve the symptoms and shorten the course of disease,and is worth to popularize in clinical.
		2017 Vol. 24 (7): 136-138 [Abstract] ( 155 ) HTML (37 KB) PDF (0 KB) ( 40 )

	139	Clinical observation on pregnancy outcomes in pregnant women with abnormal glucose metabolism
		LU Lin-lin
		Objective To observe the pregnancy outcomes in pregnant women with abnormal glucose metabolism.Methods One hundred cases of pregnant women with abnormal glucose metabolism from January 2014 to January 2016 were selected as the observation group,another 100 pregnant women with normal glucose metabolism delivered in our hospital were selected as the control group.The pregnancy outcomes including delivery mode,complications of pregnant women,complications of the fetus and neonatal in the two groups were compared.Results The rate of cesarean section in the observation group was 75.00%,much higher than that in the control group(10.00%),the difference was statistically significant(P＜0.05).The incidence of complications of pregnant women in the observation group was 35.00%,the incidence of complications of fetal was 25.00%,and the incidence of complications of neonatal was 21.00%,was higher than that in the control group(13.00%,8.00%,5.00%),the differences were statistically significant(P＜0.05).Conclusion Pregnancy with abnormal glucose metabolism can lead to serious complications in pregnant women and fetuses with the adverse effects on the health of pregnant women and the development of newborns,which should take intensive measures on prevention and control.
		2017 Vol. 24 (7): 139-141 [Abstract] ( 129 ) HTML (37 KB) PDF (0 KB) ( 35 )

	142	Contrast of ultrasonic characteristics between non-lactating mastitis and breast cancer
		HUANG Shan-shan;LI Zheng-yi;GUAN Lin-jun
		Objective To compare and analyze ultrasonic characteristics between non-lactating mastitis and breast cancer. Methods 37 cases of patients with non-lactating mastitis treated in our hospital from June 2014 to September 2015 were selected as group A and at the same time 34 cases of patients with breast cancer were selected as group B.All patients in two groups were confirmed by pathological examination and preoperative color Doppler ultrasound examination was performed to observe the sonographic appearance of tumor in the patients in two groups.Results In group A,among patients with preoperative ultrasound diagnosis 15 cases were grade 2,14 cases were grade 3 and 8 cases were misdiagnosed as grade 4,while in group B,patients with preoperative ultrasound diagnosis showed that there were 8 cases in grade 3 and 26 cases in grade 4.There was no statistical significance in mass blood supply,boundary definition,rear attenuation and lift and right distribution in two groups(P＞0.05).The differences of micro calcification of tumor,blood flow resistance index,aspect ratio,axillary lymph node enlargement and local liquefaction in two groups had statistical significance(P＜0.01).Conclusion The ultrasonic imaging characteristics of breast cancer and non-lactating mastitis are partly similar,but the micro calcification of tumor,blood flow resistance index,aspect ratio,axillary lymph node enlargement and local liquefaction condition have different characteristics,which can provide an important reference for disease identification and diagnosis.
		2017 Vol. 24 (7): 142-144 [Abstract] ( 112 ) HTML (33 KB) PDF (0 KB) ( 33 )

	145	Application effect comparison of MSCT and CTPI in evaluation of traumatic diffuse brain swelling
		ZHANG Ke;LIU Shao-guang;ZHANG Jian-hua;WEI Xiao-dong;ZHANG Dong-zhi
		Objective To compare the application effect of brain multi-slice spiral CT(MSCT)and CT perfusion imaging(CTPI)in evaluation of traumatic diffuse brain swelling(DBS).Methods Altogether 100 cases of patients with DBS from January 2015 to October 2016 were selected as study object.All the patients were scanned by using GE light speed 64-slice spiral CT machine and underwent conventional MSCT and CTPI examinations at 2 to 6 hours after injury and CTPI re-examinations within 72 hours.The detection rate of DBS by using MSCT and CTPI were compared, cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT)and the relationship between ultra clear color images and prognosis of DBS were analyzed.Results The detection rate of DBS by using MSCT was 88.0%, significantly lower than that of CTPI(96.0%)(P＜0.01);after treatment,CBF and CBV was increased,while MTT was decreased,the difference of CBF,CBV and MTT between initial examination and reexamination was statistically significant (P＜0.01).Conclusion MSCT and CTPI have good application effect in evaluation of DBS,but CTPI can effectively assess the prognosis of patients.By using the color image,disease change can be directly evaluated and observed,which is worthy of clinical application.
		2017 Vol. 24 (7): 145-146转149 [Abstract] ( 136 ) HTML (35 KB) PDF (0 KB) ( 41 )

	147	Clinical value of CT and MRI in the early diagnosis of acute cerebral infarction
		HUANG She-lei;MA Jie
		Objective To study the advantages and disadvantages of CT and MRI in patients with acute cerebral infarction(ACI)in order to provide reference for early clinical diagnosis.Methods A total of 64 ACI patients treated in our hospital from September 2015 to October 2016 were selected as the research objects.According to different examining methods,they were evenly divided into CT group and MRI group,32 cases in each group.CT and MRI were performed in the corresponding groups.The definite diagnosis rate and the conditions of detected lesion were analyzed and compared in two groups.Results In the CT group,there were 21 cases detected with infarcted lesions,and the definite diagnosis rate was 65.63%;in the MRI group,the number of infarcted lesions detected was 31 cases accounting for 96.88%in the definite diagnosis rate.The brain stem infarction was not found in the CT group,but found in the CT group,which was displayed a statistical difference between two groups(P＜0.05).The mean area of the infarcted lesion detected in the MRI group was significantly larger than that in the CT group,which was displayed a statistical difference(P＜0.05). Conclusion For ACI patients,MRI examination has a higher accuracy compared with CT and can clearly display the size and shape of the lesion,which is more beneficial to the definite diagnosis at an early stage and is worthy of clinical application and promotion.
		2017 Vol. 24 (7): 147-149 [Abstract] ( 129 ) HTML (36 KB) PDF (0 KB) ( 37 )

	150	Comparative study on antihypertensive therapy with combined drugs in patients with salt-sensitive hypertension in Ronggui Area
		AI Li;YIN Hua;LIANG Si-qi;LUO Wen-lan;TANG Hua
		Objective To study the effect of combined drug hypotension on the clinical indexes of patients with saltsensitive hypertension,so as to provide reference for clinical practice.Methods Patients with mild to moderate essential hypertension who were selected from August 2014 to August 2016(with a fall-out rate of 10%),and were intended to salt sensitive essential hypertensive according to the salt load test,60 patients with essential hypertension were selected as object of study.The patients were divided into group a and group b,30 cases in each groups,according to the patients received drug treament.Patients in group a were given Amlodipine and Irbesartan,patients in group b were treated with Indapamide combined with Irbesartan for treatment,they were treated for 12 weeks,followed up once every 2 weeks.The changes of blood pressure,renal function and urinary microalbumin in patients before and after 12 weeks of treatment were compared.Results After 12 weeks of treatment,systolic and diastolic blood pressure of two groups were lower than before treatment,group b was lower than group a,with significant difference(P＜0.05).After treatment,serum creatinine (BUN),serum creatinine(SCr)and urinary microalbumin(mAlb)of two groups were decreased compared with before treatment,with significant differences(P＜0.05),and the serum K+of group a was decreased(P＜0.05).There was no significant difference in group b before and after treatment(P＞0.05).After treatment,BUN,SCr and mAlb in group b were significantly higher than those in group a which were significant differences(P＜0.05).Conclusion The combination of Indapamide and Irbesartan in treatment of salt-sensitive hypertension is better,which can improve the renal function and maintain the stability of electrolyte.The clinical effect is significant.
		2017 Vol. 24 (7): 150-152 [Abstract] ( 143 ) HTML (40 KB) PDF (0 KB) ( 30 )

	153	Clinical effect of Sodium nitroprusside combined with dopamine in treatment of chronic heart failure
		HUANG Xiu-qin;WU Li-jun;ZHUANG Qiu-fang
		Objective To explore the clinical effect of Sodium nitroprusside combined with dopamine in the treatment of chronic heart failure.Methods 70 patients with chronic heart failure admitted in our hospital from January 2015 to November 2016 were divided into two groups,35 cases in each groups according to the difference of the patients′treatment methods.The patients who received conventional treatment were set as the control group,the patients who received SNP combined with dopamine were treated as the study group,and the clinical therapeutic effects of the two groups were compared and analyzed.Results The total effective rate of the study group was higher than that of the control group,the decrease of heart rate,systolic blood pressure and diastolic blood pressure were lower than those of the control group.The improvement of LVEF,LVD,LVFS and cardiothoracic ratio were better than that of the control group,with statisticant differences(P＜0.05).Conclusion Sodium nitroprusside combined with dopamine is effective in the treatment of chronic heart failure.It is effective in improving the clinical symptoms of patients with chronic heart failure and has clinical application value.
		2017 Vol. 24 (7): 153-155 [Abstract] ( 138 ) HTML (41 KB) PDF (0 KB) ( 27 )

	156	Analysis of micro ecological status of upper respiratory tract in adults aged 30 to 50 years old in the urban area of Shenyang
		XU Jia;CHEN Kui-min;CHEN Dong-mei;XU Jing;HAI Xiao-ou;ZHOU Yuan;XIAO Chun-ling
		Objective To understand the diversity of the upper respiratory tract microflora and the constitution of dominant microflora in healthy adults so as to provide a scientific basis for the prevention of respiratory tract infections via oral approach.Methods Altogether 60 healthy adults aged 30 to 50 years old in the urban area of Shenyang from April to June in 2012 were randomly selected as the objects of this research.The samples were collected through aseptic throat swab.The quantitative analysis and qualitative identification of microflora were made.Results The proportion between postpharyngeal aerobic bacteria and anaerobic bacteria in 60 healthy adults aged 30 to 50 years old in the urban area of Shenyang was 2.51∶1;the aerobic and anaerobic bacteria with higher detection rate included Streptococcus mitis, Streptococcus oralis,Streptococcus salivarius,Neisseria sicca,Neisseria cinerea and Measles twin cocci,Anaerococcus prevotii,Veillonella,Propionibacterium propionicus etc.;the bacteria with higher detection rate also had higher constituent ratio of strains.Conclusion The dominant microflora of upper respiratory tract pharynx is constituted by both the postpharyngeal aerobic bacteria and anaerobic bacteria with higher detection rate and higher constituent ratio in healthy adults aged 30 to 50 years old in the urban area of Shenyang,which plays an important role in maintaining the inherent ecological balance in the respiratory system,further clarifies its ecological significance,and provides a theoretical basis for the research on application of alternative probiotic strains in development of respiratory bacteria preparation.
		2017 Vol. 24 (7): 156-158 [Abstract] ( 118 ) HTML (37 KB) PDF (0 KB) ( 34 )

	159	Investigation and clinical analysis of anemia in hospitalized elderly patients in Yingtan Area
		ZENG Yuan-ying;WANG Mei-ying;CHENG Hong-ping;SHI Xiang-qing
		Objective To investigate the prevalence of anemia among elderly hospitalized patients in Yingtan City,and to explore the causes of anemia.Methods A retrospective analysis was conducted among all elderly(≥60 years old)patients in Yingtan People′s Hospital from January to June in 2014.850 cases of 5632 patient samples were diagnosed with anemia.Based on these inpatient samples,and the clinical data were analyzed statistically.Results The prevalence of anemia in all elderly patients was 15.1%,while 78.8%of those were diagnosed as mild anemia,18.0%were moderate and 3.2%were severe.The incidence of anemia increased with age.The top five pathogenesis of anemia in elderly hospitalized patients was found as malignancy,respiratory system disease,kidney disease,digestive system disease and cardiovascular system disease respectively.Conclusion The prevalence of anemia among elderly inpatients is high,the majority is mild.Furthermore,the symptoms of anemia coexist with primary diseases and sometimes are obscured,therefore, anemia is usually ignored or neglected by patients and clinicians.Acute or chronic inflammation,gastrointestinal tumor, kidney disease are the three main factors lead to anemia among hospitalized elderly patients.
		2017 Vol. 24 (7): 159-161转165 [Abstract] ( 129 ) HTML (43 KB) PDF (0 KB) ( 36 )

	162	Research on the risk factors of metabolic syndrome in Changsha Area
		HE Xia;WANG Xing-na;HU Xiang-ming;SONG Jun-hua;CHEN Hai-bin;QU Mei-rong;CHEN Yong;ZHANG Ya-ya
		Objective To study the risk factors of metabolic syndrome(MS)in Changsha Area.Methods A total of 2961 healthy residents aged 25 to 80 years old in Changsha from May 2012 to May 2013 were selected for questionnaires, physical examinations and related metabolic indexes test.The influence factors of MS were analyzed by Logisitic review. Results There were 630 patients with MS in line with CDS criteria accounting for 21.28%of all residents.In all subjects,the incidence of central obesity,hyperlipidemia,and low HDL-C was 30.77%,25.23%,and 22.76%.The proportions of blood pressure increasing,FPG,and postprandial blood glucose were 33.60%,20.16%,and 20.57%in turn.The incidence of diabetes was 23.54%.Among all participants,the morbidity of high blood pressure was the highest.There was no difference in detection rate in male and female in merging group three.In groups of absence of MS and merging group one,the female detection rates were much higher than those in male(P＜0.05).The male detection rates in merging groups two and four were greatly higher than those in female(P＜0.05).The onset of MS was not significantly related to whether drinking and occupation.The prevalence of MS in rural areas was significantly higher than that in urban(P＜0.01).With the improvement of educational levels,the number of patients suffered from MS was gradually decreased(P＜0.01).The incidence of MS patients preference for sweet food was much higher than that in patients who didn′t hate or like sweet food(P＜0.01).The morbidity of MS in patients with smoking,and family histories of hypertension,diabetes mellitus,and obesity was much higher in comparison with those who didn′t have(P＜0.01).Logistic analysis showed that age,smoking, family history of hypertension,family history of diabetes mellitus,and family history of obesity were risk factors of MS occurrence.The educational degree was the protective factor of MS occurrence.Conclusion The incidence of MS is high in Changsha Area.During treatment,comprehensive therapeutic method is adopted targeting on the risk factors of MS in order to avoid the related diseases.
		2017 Vol. 24 (7): 162-165 [Abstract] ( 129 ) HTML (40 KB) PDF (0 KB) ( 43 )

	166	Investigation on the characteristics of patients with overlap syndrome of bronchial asthma and chronic obstructive pulmonary disease and the corresponding treatment strategy
		LING Wen-shan;HOU Xian-yun;HUANG Shu-hua
		Objective To investigate the characteristics of the patients with overlap syndrome of bronchial asthma and chronic obstructive pulmonary disease(ACOS)in order to make the best choice for the treatment of ACOS patients. Methods A total of 82 patients with ACOS(ACOS group)treated in the Sixth People′s Hospital of Nansha District in Guangzhou City from December 2015 to August 2016 were selected.they were treated by Montelukast 10 mg each time, once per day.The drug should be taken before sleep and course of treatment was lasted for 12 weeks.The clinical data from the other two groups of 100 patients with chronic obstructive pulmonary disease(COPD group)and 85 asthmatic patients(asthma group)in the same period were retrospectively analyzed.The general condition,pulmonary function,proportion of induced sputum cell eosinophil granulocyte(EOS),fractional exhaled nitric oxide(FENO),St.George respiratory questionnaire(SGRQ)assessment,and frequency of acute exacerbations within 2 years were investigated and analyzed among three groups.Results There were no statistical differences in gender,ethnics,educational background,and health care(P＞0.05).In the ACOS group,average age,proportion of frequent lower respiratory tract infection in children, yearly decreasing level of forced expiratory volume in one second(FEV1)within 2 years,SGRQ score,and frequency of acute exacerbations within 2 years were much higher than those in the COPD group and asthma group,which were displayed statistical differences(P＜0.05).In the ACOSgroup,the indexes of body mass index and diffusion function DLCO/VA(%)were both greatly lower in comparison with those in the COPD group and asthma group with statistical differences(P＜0.05).For ACOS patients,the levels of FEV1, FEV1%,peak expiratory flow(PEF),and PEF%were all much higher compared with those before treatment with statistical differences(P＜0.05).Conclusion In clinic,pulmonary function decreases fast in ACOS patients,quality of life-related with health is poor,and is inclined to repeated acute exacerbations.Montelukast therapy can effectively enhance pulmonary function in ACOS patients and provide a strong basis for clinical research.
		2017 Vol. 24 (7): 166-169 [Abstract] ( 123 ) HTML (41 KB) PDF (0 KB) ( 30 )

	170	Current situation and countermeasures of occupational exposure for medical staff from 2013 to 2015
		ZHANG Huang-hui;WANG Shi-hong;LIU Hong-wei
		Objective To study the distribution and proportion of occupational exposure among medical staff in the hospital so as to provide basis for making countermeasures.Methods The occupational exposure medical staff in the hospital from January 2013 to December 2015 was investigated and studied to analyze the present situation and the deep reason.Results Altogether 236 cases of occupational exposure occurred to medical staff in our hospital from 2013 to 2015.As for the distribution of occupational exposure,Department of Surgery took up 51.3%,followed by Department of Internal Medicine and Department of Obstetrics and Gynecology.Regarding the profession of medical staff,nurses suffered most from occupational exposure(accounting for 44.5%),followed by internships(accounting for 30.1%).As for the distribution of the source of exposure,hepatitis B was the most common one,followed by hepatitis C,syphilis,AIDS,etc.. With regard to the distribution of the route of exposure,blood drawing and injection were the main cause of occupational exposure,both of which cumulatively accounted for more than 50%from 2013 to 2015.Conclusion In view of the grim occupational exposure situation for medical personnel,it is of great necessity to strengthen training and education, standardize the operation process and post-exposure emergency treatment process and to establish a comprehensive monitoring system so as to effectively reduce the incidence of occupation exposure.
		2017 Vol. 24 (7): 170-172 [Abstract] ( 129 ) HTML (37 KB) PDF (0 KB) ( 39 )

	173	Clinical study and analysis of types of constitution of traditional Chinese medicine in adolescent girls suffering from dysmenorrhea
		CHEN Qiao-hua;WANG Wei-hua
		Objective To analyze the relationship between constitution of traditional Chinese medicine(TCM)and morbidity of dysmenorrhea in adolescent girls.Methods From January 2015 to March 2016,120 patients with primary dysmenorrhea were visited in our hospital for treatment were selected.Another group of 120 non-dysmenorrhea participants for physical examinations in the same period was collected.The questionnaire was used to analyze the type of TCM constitution.Results The proportion of constitutions of qi deficiency,yang deficiency,stagnant blood,and qi depression in dysmenorrhea group was much higher than those in the healthy participants group(P＜0.05).With the severity of dysmenorrhea aggravating,the incidence of the types of TCM constitution in qi deficiency,yang deficiency,stagnant blood, and qi depression was in a rising tendency.Conclusion For patients with primary dysmenorrhea,constitutions of qi deficiency,yang deficiency,stagnant blood and qi depression are the main types,which should be paid great attention to observe the prevention and treatment on the disease.
		2017 Vol. 24 (7): 173-175 [Abstract] ( 126 ) HTML (35 KB) PDF (0 KB) ( 29 )

	176	Effects comparison of compound Danshen Injection and 50%Magnesium Sulfate Solution wet deposition in treating neonatal transfusion extravasation
		YUAN Yu-huan;LIU Er-ying;MAI Hui-qiong;LUO Huan-ping
		Objective To observe the clinical effects of compound Danshen Injection and 50%Magnesium Sulfate Solution wet deposition in treating neonatal transfusion extravasation.Methods 131 neonatal were accepted intravenous infusion from March 2015 to March 2016 of our hospital were selected.All neonatal had the symptoms of transfusion extravasation.Neonatal were randomly divided into control group(65 cases)and observation group(66 cases).Neonatal in control group were used 50%Magnesium Sulfate Solution wet deposition,and neonatal in observation group were used compound Danshen Injection.Swelling time,effective time,treatment effects and adverse effects in two groups were compared.Results The beginning swelling time,totally swelling time and effective time in observation group were respectively(2.78±0.57),(9.12±1.13),(5.73±0.63)h,and the control group was respectively(5.61±1.49),(16.32±1.43),(10.54±1.05)h in control group,those time of the observation group was shorter than the control group,and the differences were significant(P＜0.01).The effective time in observation group was 98.48%,which was 73.85%in control group,and the difference was significant(P＜0.01).The incidence rate of adverse effects in observation group was 0,which was 12.3%in control group,and the difference was significant(P＜0.05).Conclusion Using compound Danshen Injection wet deposition for neonatal with transfusion extravasation in clinical,which has the advantages of rapid onset,good effects and high safety, and it is worth to popularize.
		2017 Vol. 24 (7): 176-179 [Abstract] ( 148 ) HTML (43 KB) PDF (0 KB) ( 32 )

	180	Application effect of solution-focused approach on psychological nursing in first-episode depression patients
		MENG Juan;KOU Hai-yan
		Objective To explore the application of solution-focused approach on psychological nursing in first-episode depression patients in order to provide theoretical guidance for clinical nursing.Methods A total of 172 patients with first-episode depression admitted into our hospital from January 2010 to January 2015 were selected.The patients were evenly divided into observation group and control group by a random number table.In the control group,regular psychological nursing was used,while in the observation group,combination of the conventional mode and solution-focused approach were adopted.The anxiety and depression before and after intervention were compared and analyzed by self-rating anxiety scale(SAS)and self-rating depression scale(SDS)in the two groups.Results Before intervention,there were no statistical differences in scores of SDS and SAS in both groups(P＞0.05).After intervention,the scores of SDS and SAS in the two groups were all greatly lower than those before,with statisticant differences(P＜0.01),after intervention,there were statisticant differences in scores of SDS and SAS(P＜0.01).Conclusion Solution-focused approach has a significant guiding effect on the first-episode depression,which can improve the patient′s mental state and help patients effectively alleviate anxiety and depression.
		2017 Vol. 24 (7): 180-182 [Abstract] ( 123 ) HTML (34 KB) PDF (0 KB) ( 42 )

	183	Study on the effect of psychological nursing intervention on compulsory medical treatment for the patients with schizophrenia
		LIU Jia;CUI Qian;XIE Ji-qun
		Objective To explore the application effect of psychological nursing intervention in compulsory medical treatment for the patients with schizophrenia.Methods 30 patients with schizophrenia in rehabilitation period who were hospitalized in the compulsory treatment center of Guangzhou Municipal Public Security Bureau from January 2014 to December 2015 were selected.Individual psychological intervention and collective psychological intervention were carried out for the patients for a period of 2 months on the basis of pharmaceutical treatment(BPRS),Krawiecka symptom scale,SDSS,SDS,SAS were used to evaluate the effect of psychological nursing intervention before and after the intervention.Results The scores of Krawiecka,SDSS,SAS and SDS were(11.3±3.3),(6.1±1.5),(53.3±5.7)and(51.2±6.7)points before the treatment respectively,the scores of Krawiecka,SDSS,SAS and SDS were(5.2±2.1),(4.3±1.6),(45.2±5.2),(41.3± 6.1)points after the treatment respectively,the differences between before and after intervention was statistically significant(t=2.987,1.093,2.927,2.168,P＜0.05);the scores of all factors of BPRS were decreased significantly,and the overall score was reduced from(41.5±8.3)points to(33.6±8.6)points,the differences between before and after intervention was significant(P＜0.05).Conclusion Psychosocial nursing intervention in the compulsory medical treatment for the patients with schizophrenia can reduce the negative emotions of patients and help them return to their family and return to society.
		2017 Vol. 24 (7): 183-185 [Abstract] ( 164 ) HTML (43 KB) PDF (0 KB) ( 35 )

	186	Application effect of early psychological intervention and behavior management in the treatment of diabetic foot
		LIU Yuan-qing;DENG Guo-bao;CHEN Xue-qun;LIU Yang-you
		Objective To explore the application effect of early psychological intervention and behavior management in the treatment of diabetic foot.Methods 180 diabetic foot patients from January 2015 to July 2016 in our hospital were selected.They were randomly divided into control group and experimental group,and each group was 90 cases.Patients in control group were used general psychological intervention and behavior management,and the experimental group was used early psychological intervention and behavior management.SAS and SDS score when out of the hospital and the standard rate of self-management behavior after nursing between two groups were compared.Results SAS and SDS score in the experimental group were significantly lower than those in the control group when out of the hospital,with the significant differences(P＜0.01).After nursing,the diet control,foot care,self-monitoring of blood glucose,planning exercise,high blood glucose management in experimental group were significantly better than those in control group,with the significant differences(P＜0.05).Conclusion The effect of early psychological intervention and behavior management in patients with diabetic foot is obvious,which can improve the anxiety and depression of the patients,improve their self-care management behavior compliance rate and it is worth popularizing and applying in clinic.
		2017 Vol. 24 (7): 186-188 [Abstract] ( 158 ) HTML (33 KB) PDF (0 KB) ( 34 )

	189	Effect of high-quality nursing service mode guidanceon pregnancy outcomesin patients with dangerous placenta previa
		CONG Feng-hui;SUN Qiang
		Objective To investigate the effect of high-quality nursing service on pregnancy outcomes in patients with dangerous placenta previa.Methods Altogether 50 patients with dangerous placenta previa who were treated in our hospital from November 2014 to September 2016 were randomly divided into observation group and control group,with 25 cases in each group.The control group was cared with conventional nursing mode,while,the observation group was cared with high quality nursing on the basis of control group.The nursing intervention effect of the two groups was evaluated.Results The complication rate of observation group was 12.0%,significantly low than that of control group of 28.0%(P＜0.05);the VAS-A score of observation group was low than that of control group(P＜0.05);giant infants and infants with low birth weight appeared in two groups;the incidence rate of newborns asphyxia and fetal distress of control group was slightly higher than that of observation group(P＞0.05);the satisfaction degree of observation group was 96.0%,high than that of control group of 80.0%(P＜0.05).Conclusion High-quality nursing care is a comprehensive nursing method that can reduce the incidence of postoperative complications,accelerate the recovery of the patients and reduce the incidence of adverse pregnancy outcomes,which has a significant effect in nursing care of patients with placenta previa.
		2017 Vol. 24 (7): 189-191 [Abstract] ( 144 ) HTML (40 KB) PDF (0 KB) ( 39 )

	192	Clinical effect of pelvic floor muscle exercise combined with neurological reconstruction on constipation after vaginal delivery
		MAI Xi-xian;TANG Shi-xiao;CHEN Yue-lan
		Objective To explore the clinical effect of early intervention of pelvic floor muscle exercise combined with neurological reconstruction on constipation after vaginal delivery.Methods 240 cases of puerpera with a history of constipation who delivered in our hospital were selected from December 2015 to March 2016.According to the random number table method,the patients were divided into observation group and control group,120 patients in each groups.Patients in the control group were given neurological reconstruction according to clinical experience.Patients in the observation group were further given pelvic floor muscle reconstruction on the basis of the control group.The first defecation time and constipation symptom score(clinical experience table,out of 10 points)were recorded and statistically analyzed in both groups.Postpartum defecation comfort questionnaire(centesimal system)was used to investigate the defecation status of the patients.Results The time of first defecation was(7.3±2.2)days in the observation group and(12.9±3.6) days in the control group,the difference was significant(t=14.540,P=0.000).The constipation scores in the observation group was(9.7±0.8)scores,and the control group was(5.3±1.4)scores,the difference was significant(t=29.892,P=0.000). The defecation comfort scores before the treatment in the observation group was(81.2±9.8)scores,significantly higher than that of(54.9±10.9)before the treatment(t=19.655,P=0.000),the difference was significant compared with that of (58.5±10.7)scores in control group during the same period(t=17.138,P=0.000).Conclusion The clinical effect of early intervention of pelvic floor muscle exercise combined with neurological reconstruction on constipation after vaginal delivery is significant and worthy of widespread application.
		2017 Vol. 24 (7): 192-194 [Abstract] ( 145 ) HTML (37 KB) PDF (0 KB) ( 42 )

	195	Effect of Early Rehabilitation Nursing on the Activity of Daily Living in Patients with Acute Myelitis
		WANG Jin-jun;LI Bin-xin;LIU Jun-yi;WANG Ying
		Objective To explore the effect of early rehabilitation nursing on the activities of daily living in patients with acute myelitis.Methods 72 patients with acute myelitis were treated in our hospital from October 2015 to October 2016 as the object of study and were divided into control group and observation group,36 cases in each groups.The control group was given routine care,the observation group was given early rehabilitation care.Before and after nursing, Barthel index was used to evaluate the living activity and quality of life of the patients.The ability of daily living activities,the strength of both lower limbs and the quality of life were compared between the two groups of patients.Results There was no significant difference in the activity of daily living between two groups on admission(P＞0.05).The ability of daily activities of two groups when out of the hospital was better than that on admission(P＜0.05),and the improvement of the observation group was more obvious(P＜0.05).The strength and quality of life of the patients with acute myelitis after nursing were better than those of the control group(P＜0.05).Conclusion Early rehabilitation nursing is an effective nursing model to improve the living ability of patients with acute myelitis.It is helpful to improve the muscle strength and quality of life of patients with lower limbs,and the clinical value is high.
		2017 Vol. 24 (7): 195-197 [Abstract] ( 135 ) HTML (42 KB) PDF (0 KB) ( 35 )

Copyright © Editorial Board of 中国当代医药
Supported by:Beijing Magtech