慢性肾脏病非透析患者心肌肌钙蛋白升高的应用进展

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Abstract Cardiac troponin(cTn)can be increased at the time of myocardial necrosis,which,as is universally known,it is a marker for diagnosis of myocardial injury,especially in the diagnosis of acute coronary syndrome(ACS)that have been recognized by at home and abroad.However,the increase of cTn is also seen in non-coronary heart diseases(myocarditis,arrhythmia,heart failure)and non-heart diseases(chronic kidney disease,sepsis,stroke etc.).In recent years,it has no longer been something unusual that significantly higher serum cTn is detected in patients with chronic kidney disease (CKD)than that of non-CKD patients.As for the reason,on the one hand,the elevated levels of cTn is subject to kidney diseases,such as decreased renal clearance rate;on the other hand,CKD complicated with cardiovascular diseases(CVD) eventually leads to the rise of cTn levels.In this paper,the causes and mechanisms of elevated cTn in non-dialysis CKD, the relationship between cTn and kidney diseases as well as its role in prediction of CVD with ACS are mainly discussed.

Key words： Chronic kidney disease Cardiac troponin Cardiovascular disease Hemodialysis

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	DOU Li-na
	JIANG Hong-ying

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DOU Li-na,JIANG Hong-ying. Advances in the application of elevated cardiac troponin in patients with chronic kidney disease[J]. 中国当代医药, 2017, 24(7): 19-22.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I7/19

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