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| Clinical features and prognosis of the patients with acute myocardial infarction complicated with gastrointestinal bleeding |
| YANG Ming-yu |
| Department of Cardiology,People′s Hospital of Huazhou City in Guangdong Province,Huazhou525100,China |
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Abstract Objective To explore the clinical features and prognosis of patients with acute myocardial infarction(AMI) complicated with gastrointestinal bleeding.Methods 193 patients treated in our department of cardiology from April 2012 to April 2014 were selected as research objects.According to the disease types,the patients were divided into three groups∶group A(AMI without gastrointestinal bleeding),totally 100 cases,group B(gastrointestinal bleeding following AMI),totally 52 cases,group C(AMI following gastrointestinal bleeding)for after patients,totally 41 cases.The difference of biochemical indexes and clinical tmeament among three groups were observed.After two-years follow-up,the recurrence (including angina pectoris,heart failure,nonfatal AMI,etc.)and mortality of the three groups were compared.Results The biochemical indicators and clinical treatment of patients in three groups differed greatly from each other;glomerular filtration rates of group B and C were significantly lower than that of group A,and activated partial thromboplastin time (APTT)of group B and C was longer than that of group A,and hemoglobin of group B and C was lower than that of group A,and these differences were statistically significant(P＜0.05).The use of anticoagulant drug in three groups such as Aspirin and Clopidogrel were differed from each other,and differences were statistically significant(P＜0.05).Although patients in group B and C both were with gastrointestinal bleeding,patients in group B needed less blood transfusion than that in group C,and difference was statistically significant(P＜0.05).After two-years follow-up,the recurrence of circulatory dysfunction diseases and mortality of group B and C were more than those of group A,and differences were statistically significance(P＜0.05).Conclusion AMI patients complicated with gastrointestinal bleeding have more clinical features,need more complex anticoagulant treatment,suffer more risks of recurrence,and have worse prognosis than AMI patients without gastrointestinal bleeding.
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