Abstract:Objective To analyze the clinical effect of Goserelin Acetate Sustained-Release Depot combined with laparoscopic surgery in the treatment of endometriosis. Methods Sixty patients with endometriosis treated in our hospital from October 2017 to November 2018 were selected as the subjects, they were divided into treatment group and routine group, with 30 cases in each group. The routine group was treated with laparoscopic surgery, and the treatment group was given Goserelin Acetate Sustained-Release Depot combined with laparoscopic surgery. The total effective rate of treatment and clinical symptoms were compared between the two groups. Results The total effective rate of the treatment group was 93.33%, higher than that of the conventional group (73.33%), and the difference was statistically significant (P<0.05). After treatment, the pelvic tenderness, dysmenorrhea, irregular menstruation, coital pain and infertility in the treatment group were better than those in the conventional group, and the differences were statistically significant(P<0.05). The recurrence rate in the treatment group was lower than that in the routine group, and the rate of second pregnancy was higher than that in the routine group, the differences were statistically significant (P<0.05). Conclusion Goserelin Acetate Sustained-Release Depot combined with laparoscopic surgery can effectively treat endometriosis, and can improve the symptoms of dysmenorrhea, irregular menstruation, sexual pain, infertility, etc., reduce the recurrence rate of endometriosis and improve The rate of pregnancy again is worth promoting.