Objective To investigate the clinical value of serum anti-aging factor (Klotho),secreted frizzled related protein-1 (sfrp-1)and C-reactive protein (CRP)in the detection of diabetic nephropathy (DN)patients.Methods By retrospective analysis,60 patients with DN admitted to the First People's Hospital of Jiujiang from November 2020 to November 2022 were selected as the DN group,and 60 healthy subjects who underwent physical examination during the same period were included as the control group.The changes of serum Klotho,sfrp-1 and CRP levels in the DN group and the control group were detected.The DN group was divided into simple diabetes group (urinary protein excretion rate [UAER]＜20 μg/min],early DN group (200 μg/min≥UAER≥20 μg/min) and clinical DN group (UAER＞200 μg/min),and the serum levels of Klotho,sfrp-1 and CRP were compared among all groups.The diagnostic value of serum Klotho,sfrp-1 and CRP on the degree of renal injury was analyzed by receiver operating characteristics (ROC) curve.Results The levels of sfrp-1 and CRP in DN group were higher than those in control group,and the level of Klotho wes lower than that in control group,with statistical significance (P＜0.05).The level of Klotho in clinical stage DN group was lower than that in early stage DN group and simple diabetes group,the level of Klotho in the early DN group was lower than that in the simple diabetes group,and the levels of sfrp-1 and CRP in clinical stage DN group were higher than those in early stage DN group and simple diabetes group,the levels of sfrp-1 and CRP in early stage DN group were higher than those in simple diabetes group,with statistical significance(P＜0.05).Spearman analysis showed that Klotho level was negatively correlated with the degree of kidney injury in DN patients,while Psfrp-1 and CRP levels were positively correlated with the degree of kidney injury (P＜0.05).The area under ROC curve (AUC)of Klotho,sfrp-1 and CRP combined in the diagnosis of kidney injury was higher than that of single detection.Conclusion The higher the degree of renal injury in DN patients,the higher the level of serum sfrp-1 and CRP,and the lower the level of serum Klotho.

Objective The diagnostic value of serum procalcitonin in the early abdominal infection after abdominal surgery was evaluated by meta-analysis.Methods CNKI,VIP,Wanfang,SinoMed,PubMed,Springer and other databases were searched by computer.The literatures on procalcitonin and abdominal infection published from January 2001 to January 2023 were searched by reference tracing and manual retrieval.References were screened according to inclusion and exclusion criteria,and after data extraction and literature quality evaluation,data analysis was performed using RevMan 5.3 software and Meta Disc 1.4 software.Results A total of 2 021 cases were included in 13 literatures,including 487 cases in the abdominal infection group and 1 535 cases in the control group.The meta-analysis showed that the sensitivity and specificity of procalcitonin in the diagnosis of postoperative abdominal infection were 75%[95%CI (71%-79%)] and 66%[95%CI(64%-68%)].The positive likelihood ratio was 3.20 [95%CI (2.26-4.54)],the negative likelihood ratio was 0.35 [95%CI(0.26-0.46)],and the AUC of SROC was 0.834 8.Conclusion Procalcitonin is effective in the diagnosis of postoperative abdominal infection,and can be used as an independent index for early prediction of abdominal infection.

Objective To investigate the clinical effect of liposuction combined with adenoidectomy in the treatment of gynecomastia(GYN).Methods Thirty GYN patients admitted to Nanchang Third Hospital from October 2021 to October 2022 were selected as the study objects,and were divided into experimental group and control group according to the odd-even admission sequence,with 15 patients in each group.The control group was treated with open surgery,and the experimental group was treated with liposuction combined with small-incision adenoidectomy.The operation related indexes,satisfaction with operation effect and psychological status of the two groups were compared.Results The intraoperative blood loss of experimental group was less than that of control group,and the length of hospitalization was shorter,with statistical significances (P＜0.05).There was no significant difference in the total incidence of complications between the two groups (P＞0.05).There were no significant differences between the two groups in breast symmetry,operative skin,nipple sensation and overall self-satisfaction score (P＞0.05).There were no significant differences in interpersonal sensitivity,obsessive symptoms,somatization and depression scores between the two groups (P ＞0.05).Conclusion Liposuction combined with small-incision adenoidectomy has a good effect on the treatment of GYN.Patients have lower intraoperative bleeding and good postoperative safety,which can ensure good surgical satisfaction and psychological status,and also have a positive effect on shortening hospital stay.

Objective To explore the application value of artificial bone pulp combined with allogeneic bone in the treatment of bone defect of limbs fracture.Methods A total of 160 patients with limb fracture and bone defect who received surgery in the Second Affiliated Hospital of Gannan Medical College from August 2021 to August 2022 were selected as the study objects.By using random number table method,they were divided into control group,artificial bone pulp group,allogeneic bone group and combined treatment group,with 40 cases in each group.In control group,autogenous cancellous bone was used to fill the bone defect.Allogeneic bone provided in the bone tissue bank of patients in the allogeneic bone group was filled at the bone defect.In the artificial bone pulp group,the artificial bone pulp was manually shaped and squeezed into the bone space for filling.In the combined treatment group,the bone pulp and allogeneic bone were combined to fill the bone defect site.The perioperative indexes,imaging status,functional scores and complications of the four groups were compared.Results The intraoperative blood loss,postoperative drainage volume and surgical cost of the combined treatment group were all lower than those of the other three groups,and the operation time and hospital stay were shorter than those of the other three groups,with statistical significance(P＜0.05).The quality of life health survey short form 36(SF-36)scores,Nottingham health scale (NHP) scores and visual analogue scale (VAS) satisfaction scores of the combined treatment group were higher than those of the other three groups,and the VAS pain scores were lower than those of the other three groups,with statistical significances (P＜0.05).The imaging results showed that all patients in the combined treatment group had callus growth at the bone graft sites by X-ray after 6 months,and the 1-year bone healing rate was higher than that in the other three groups,the difference was statistically significant (P＜0.008).The total complication rate of the combined treatment group was lower than that of the other three groups,and the difference was statistically significant (P＜0.008).Conclusion For patients with limb fracture and bone defect,artificial bone pulp combined with allogeneic bone therapy can improve perioperative indexes,promote bone healing speed,reduce the incidence of complications and improve quality of life,and the overall treatment safety is higher.

Objective To explore the effect of auricular acupoint pressing beans with electronic biofeedback on insomnia.Methods A total of 90 patients with insomnia who were hospitalized in the Fifth People's Hospital of Jiujiang,Jiangxi Province from January 2022 to June 2023 were selected as the research objects.According to the random number table method,they were divided into Group A,Group B and Group C,with 30 cases in each group.Group A was given electronic biofeedback therapy,group B was given auricular acupoint pressing beans therapy,and group C was given auricular acupoint pressing beans with electronic biofeedback therapy.The Pittsburgh sleep quality index (PSQI),Hamilton depression scale(HAMD)and Hamilton anxiety scale (HAMD)were compared between the three groups before and after treatment.Results After 4 weeks of treatment,the PSQI,HAMD and HAMA scores of the three groups were lower than those before treatment,and the differences were statistically significant (P＜0.05).After 4 weeks of treatment,the PSQI,HAMD and HAMA scores of group C were lower than those of group A and group B,and the differences were statistically significant(P＜0.05).After 4 weeks of treatment,there were no significant differences in PSQI,HAMD and HAMA scores between group A and group B(P＞0.05).Conclusion Auricular acupressure combined with electronic biofeedback therapy has a better therapeutic effect on sleep improvement in patients with insomnia.

Objective To investigate the relevant influencing factors of cognitive impairment in patients with isolated thalamic infarction treated with nimergoline combined with Xingnaojing.Methods A retrospective analysis was conducted on the clinical data of 120 patients with cerebral infarction admitted to the Department of Neurology,Hongqi Hospital Affiliated to Mudanjiang Medical College from January 2020 to December 2022.All patients received treatment with nimergoline combined with Xingnaojing.The incidence of cognitive impairment was statistically analyzed,and relevant data was organized and analyzed.Multiple logistic regression analysis was used to identify the relevant influencing factors leading to cognitive impairment.Results The incidence of cognitive impairment in patients with isolated thalamic infarction was 37.50%.Univariate analysis showed that the proportion of cognitive impairment patients aged≥60 years,hyperhomocysteinemia (Hcy),severe stenosis or occlusion of posterior circulation large vessels,and medial thalamic infarction were higher than those in non cognitive impairment patients,the differences were statistically significant (P＜0.05).There were no significant differences in gender,hypertension,diabetes,hyperlipidemia,stroke history,hyperuricemia,smoking and drinking among patients with cognitive impairment and non-cognitive impairment (P＞0.05).Multivariate logistic regression analysis showed severe stenosis or occlusion of posterior circulation large vessels (β=0.513,OR=1.670,95%CI: 1.318-2.117),hyperhomocysteinemia (β=0.679,OR=1.972,95%CI: 1.247-3.119) and medial thalamic infarction (β=0.427,OR=1.533,95%CI:1.245-1.887)were the main influencing factors for cognitive impairment in patients with isolated thalamic infarction (P＜0.05).Conclusion Severe stenosis or occlusion of large blood vessels in the posterior circulation,medial thalamic infarction,and high Hcy are important factors leading to cognitive impairment after isolated thalamic infarction.During clinical treatment,it is necessary to closely monitor changes in various indicators and improve the condition through rational medication and dietary regulation.

Objective To analyze the influencing factors and intervention strategies of postoperative hypotension in elderly carotid artery stenosis patients after stent implantation,and lay a foundation for the formulation and implementation of follow-up diagnosis and treatment measures.Methods A total of 114 carotid artery stenosis patients who underwent stent implantation from January 2020 to May 2023 at the Jiuquan Second People's Hospital were selected as the research objects,they were divided into a control group(74 cases,patients without hypotension)and an observation group(40 cases,patients with hypotension after surgery)according to whether they had hypotension after surgery.Univariate and multivariate logistic regression analysis were used to explore the risk factors of hypotension in elderly carotid artery stenosis patients after stent implantation.Results The results of univariate analysis showed that the proportion of patients with age≥70 years,bilateral stenting,presence of ulcer plaque,history of hypotension and severe stenosis of the observation group were higher than those of the control group,the differences were statistically significant (P＜0.05).Multivariate logistic analysis showed that age≥70 years(β=0.141,OR=1.513,95%CI:1.186-1.929),bilateral stent placement(β=0.422,OR=1.525,95%CI:1.121-2.074),presence of ulcerated plaque (β=0.387,OR=1.473,95%CI:1.108-1.957),history of hypotension (β=0.407,OR=1.502,95%CI:1.039-2.172),severe stenosis (β=0.415,OR=1.514,95%CI:1.100-2.084)were all risk factors for postoperative hypotension in elderly carotid artery stenosis patients after stent implantation(P＜0.05).Conclusion Age≥70 years,bilateral stenting,presence of ulcer plaque,history of hypotension,and severe stenosis were independent risk factors for postoperative hypotension in elderly carotid artery stenosis patients,follow-up interventions based on these results can reduce the risk of postoperative hypotension in elderly carotid artery stenosis patients.

Objective To observe the application effect of Baofukang Suppository combined with ozone treatment on high-risk human papilloma virus(HPV)infection in the cervix.Methods A total of 120 patients who were tested positive for HPV in gynecological examination in the Fourth Affiliated Hospital of Nanchang University from March 2018 to December 2020 were selected as research objects,and were divided into experimental group (60 cases)and control group (60 cases)according to random number table method.The control group was treated with Bafukang Suppository,the experimental group was treated with Bafukang Suppository combined with ozone therapy,and the two groups were treated for a total of 3 courses.The clinical efficacy,HPV negative conversion rate,serum tumor necrosis factor α (TNF-α) level,interleukin-6 (IL-6)level,transforming growth factor-β(TGF-β)level and total incidence of adverse reactions were compared between the two groups.Results The total effective rate of experimental group was higher than that of control group,the difference was statistically significant (P＜0.05).The negative conversion rate of HR-HPV in experimental groups was higher than that in control group,and the difference was statistically significant (P＜0.05).After treatment,the levels of TNF-α and TGF-β in experimental groups were lower than those in control group,and the levels of IL-6 were higher than those in control group,with statistical significances(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion The use of Baofukang Suppository combined with ozone therapy for high-risk cervical HPV patients has a definite effect,can improve the HPV conversion rate,and is relatively safe,which is worthy of clinical promotion and application.

Objective To explore the correlation between serum levels of late oxidized protein product (AOPP),monocyte chemoattractant protein-1 (MCP-1)and preeclampsia (PE)in pregnant women with gestational diabetes mellitus(GDM).Methods A total of 70 pregnant women with GDM complicated with PE admitted to the obstetrics Department of the Affiliated Hospital for Nationalities of Guangxi Medical University from October 2021 to September 2023 were selected as the combination group,and another 70 pregnant women with simple GDM who came to the Affiliated Hospital for Nationalities,Guangxi Medical University during the same period were selected as the non-combination group.The clinical data and laboratory indicators of the two groups of subjects were statistically analyzed.Multivariate logistic analysis was used to analyze the correlation between AOPP,MCP-1 and GDM complicated with PE.ROC was used to analyze the diagnostic value of serum AOPP and MCP-1 combined detection of GDM complicated with PE.Results Univariate analysis showed that there were statistically significant differences in age,pre-pregnancy body mass index(BMI),serum AOPP and MCP-1 expression levels between the two groups(P＜0.05).Multivariate logistic regression showed that age,pre-pregnancy BMI,serum AOPP and MCP-1 were independent risk factors for GDM complicated with PE(P＜0.05).ROC curve showed that the areas under serum AOPP,MCP-1 and their combined detection curves were 0.867,0.916 and 0.942.Conclusion AOPP and MCP-1 are closely related to the risk of GDM with PE,and have high application value in the diagnosis of the disease.

analysis between cervical lesions and HPV infection.Methods The Polymerase Chain Reaction (PCR)method was used to examine 13 000 women who underwent cervical cancer screening at Liangzhou Hospital in Wuwei City,Gansu Province,from March 2021 to September 2023.Among the screened individuals,1 200 cases were identified with HPV infection,and they underwent colposcopy and cervical biopsy.Based on the presence or absence of cervical lesions according to cervical tissue biopsy results,the patients were divided into two groups: the lesion group(n=486) and the non-lesion group (n=714).Univariate analysis was used to identify factors influencing the occurrence of cervical lesions,and multivariate logistic regression analysis was employed to analyze factors with P＜0.05 in the univariate analysis.Results The results of univariate analysis showed significant differences between the lesion and non-lesion groups in terms of age,persistent HPV infection,cervical columnar epithelial displacement,number of sexual partners,and HPV infection type(P＜0.05).Multivariateanalysisrevealed thatage ＜25 or ≥55 years(β=0.754,OR=2.126,95%CI:1.649-2.740),persistent HPV infection (β=1.048,OR=2.853,95%CI: 2.209-3.683),cervical columnar epithelial displacement (β=0.625,OR=1.868,95%CI:1.453-2.401),number of sexual partners ≥2 (β=0.625,OR=1.988,95%CI:1.546-2.556)and high-risk HPV infection type(β=0.863,OR=2.371,95%CI:1.833-3.066)were independent risk factors for the occurrence of cervical lesions.Conclusion There is a connection between HPV infection and cervical lesions,with HPV16/HPV18 being the main types of HPV infection associated with cervical lesions.Advocating for regular check-ups and implementing targeted measures for different women are of profound significance for reducing the occurrence of cervical lesions due to HPV infection and preventing cervical cancer.

 Objective To explore the influence of different perioperative body temperature intervention mode on postoperative delirium in elderly patients.Methods A total of 80 patients who planned to undergo laparoscopic radical gastrectomy in the First Hospital of Putian City from September 2021 to December 2022 were selected as the research objects.According to random number table method,the patients were divided into control group and multi-mode thermal insulation group,with 40 cases in each group.The control group used physical insulation,and the multi-mode thermal insulation group used infusion heating instrument and inflatable heating system.The changes of nasopharyngeal body temperature in the two groups were observed at different time points,and the basic information,operation time,intake and output volume,intraoperative anesthetic dosage and postoperative complications of the two groups were recorded.Postoperative delirium assessment method was used to evaluate postoperative delirium in the two groups.Results The time of extubation and PACU residence in the multi-mode thermal insulation group were shorter than those in the control group,the differences were statistically significant(P＜0.05).After anesthesia induction,the body temperature in the anesthesia maintenance period gradually decreased,and the nasopharyngeal temperature of patients in the multi-mode thermal insulation group at T5-T7 and the nasopharyngeal temperature of control group at T4-T7 were lower than that at T0,with statistical significances(P＜0.05).The incidence of intraoperative hypothermia in the multi-mode thermal insulation was lower than that in the control group,and the difference was statistically significant (P＜0.05).The incidence of postoperative delirium in multi-mode thermal insulation was lower than that in control group,and the difference was statistically significant (P＜0.05).There were no significant differences in the onset and duration of postoperative delirium between the two groups(P＞0.05).Conclusion Multi-mode thermal insulation in perioperative period can reduce the incidences of intraoperative hypothermia and postoperative delirium in elderly patients after prolonged operation.

 Objective To investigate the application effect of ultrasound-guided transversus abdominis plane block with Ropivacaine for postoperative analgesia in laparoscopic gastrectomy for gastric cancer.Methods A total of 60 patients undergoing laparoscopic gastrectomy for gastric cancer treated in the First People's Hospital of Qinzhou from November 2019 to March 2022 were selected as the research objects,and they were divided into observation group(30 cases)and control group(30 cases)according to random number table method.Patients in the observation group were treated with ultrasound-guided transversus abdominis plane block combined with Ropivacaine analgesia.The control group was given intramuscular Tramadol analgesia.Postoperative recovery,visual analogue scale (VAS)score,Ramsay sedation score,Pittsburgh sleep quality index (PSQI) score and adverse reactions were compared between the two groups.Results The postoperative first exhaust time,the first meal time,the first out of bed activity,and total length of hospital stay in the observation group were shorter than those in the control group,the postoperative VAS score and total incidence of adverse reactions were lower than those in the control group,PSQI scores were lower than those of control group,the total hospitalization cost was lower than that of control group,the differences were statistically significant(P＜0.05).Conclusion After laparoscopic gastrectomy for gastric cancer,the use of ultrasound-guided transversus abdominis plane block with Ropivacaine for analgesia can reduce postoperative pain and adverse reactions,have faster speed of recovery,lower hospitalization cost and better prognosis,and have high application value.

 Objective To investigate the effect of precision anesthesia intervention in non-cardiac surgery perioperative period in high-risk cardiovascular patients.Methods A total of 190 high-risk cardiovascular patients admitted to the First People's Hospital of Guangyuan from January to December 2022 were selected as research objects,and they were divided into observation group(95 cases)and control group(95 cases)according to random number table method.The control group was administered with general experience management,and the observation group was administered with precision anesthesia intervention measures.Serological indexes and incidence of cardiac adverse events were compared between the two groups.Results Cardiac troponin(cTn),creatine kinase isoenzyme(CK-MB),myoglobin(Mb),high sensitivity troponin T(hs-TnT),brain natriuretic peptide(BNP),N terminal pro B type natriuretic peptide(NT-proBNP)and C-reactive protein(CRP)in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).The total incidence of cardiac adverse events in observation group was lower than that in control group,and the difference was statistically significant (P＜0.05).Conclusion Precision anesthesia intervention in high-risk cardiovascular patients during non-cardiac surgery perioperative period can further reduce cardiac injury and reduce the incidence of adverse events,which is worthy of clinical application.

Objective To investigate the effect of Shengqing Jiangzhuo Huazhi Decoction combined with moxibustion in the treatment of non-alcoholic steatohepatitis (NASH) with liver depression and spleen deficiency and dampness stagnation.Methods A total of 300 patients with NASH of liver depression and spleen deficiency and dampness stagnation admitted to Shangrao Second People's Hospital from January 2022 to April 2023 were selected as the study objects,and they were divided into control group (n=150) and observation group (n=150) according to random number table method.The control group was treated with Silymarin and Polyene Phosphatidyl Choline,and the observation group was treated with Shengqing Jiangzhuo Huazhi Decoction combined with moxibustion.The traditional Chinese medicine syndrome scores,liver function indexes,blood lipid indexes and adverse reactions were compared between the two groups.Results After treatment,the scores of loose stool([0.28±0.05]points),feeling trapped and heavy all over the body([0.15±0.03]points),abdominal distension([0.37±0.14]points)and loss of appetite([0.83±0.06]points)in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).After treatment,the alanine transaminase ([57.84±5.52] U/L),total bilirubin ([33.81±2.79] μmol/L),aspartate transaminase ([50.61±6.22] U/L),triglyceride ([2.01±0.42] mmol/L),cholesterol ([4.32±0.51]mmol/L)in the observation group were lower than those in the control group,with statistically significant differences (P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Shengqing Jiangzhuo Huazhi Decoction combined with moxibustion is effective in the treatment of NASH patients with liver depression and spleen deficiency and dampness stagnation,which can improve liver function,down-regulate blood lipid indexes,and has fewer adverse reactions and high safety.

Objective To evaluate the effect of Traditional Chinese Medicine Nourishing Yin and Tonifying Yang Prescription in the treatment of infertility patients with polycystic ovary syndrome of kidney qi deficiency on dynamic multi-parameters of ultrasound.Methods A total of 80 patients with polycystic ovary syndrome of kidney qi deficiency admitted to Jiangxi Maternal and Child Health Hospital from January 2022 to January 2023 were selected as the research objects.According to the random number method,they were divided into observation group (40 cases)and control group (40 cases).The control group was treated with Clomiphene Citrate Tablets,and the observation group was treated with Traditional Chinese Medicine Nourishing Yin and Tonifying Yang Prescription on the basis of the control group.The treatment effect,follicular development,hormone level,uterine artery blood perfusion and endometrial thickness were compared between the two groups.Results The effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).After treatment,the number of follicles and dominant follicles in the observation group were more than those in the control group,and the differences were statistically significant (P＜0.05).After treatment,the luteinizing hormone (LH),follicle stimulating hormone (FSH)and testosterone (T)of the observation group were lower than those of the control group,and the estradiol(E2)was higher than that of the control group,and the differences were statistically significant(P＜0.05).After treatment,the pulse pressure index(PI)and resistance index(RI)of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).After treatment,the endometrial thickness of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion The application of Traditional Chinese Medicine Nourishing Yin and Tonifying Yang Prescription in the treatment of infertility patients with polycystic ovary syndrome of kidney qi deficiency can actively improve the patient's hormone level and uterine artery blood perfusion,promote follicle development,increase endometrial thickness,and improve symptoms,which is worthy of promotion.

Objective To explore the effect of traditional Chinese medicine acupuncture on gastrointestinal dysfunction in severe patients.Methods A total of 142 severe patients with gastrointestinal dysfunction hospitalized in the Department of Critical Care Medicine,the First People's Hospital of Lanzhou City from November 2020 to August 2023 were selected as the research objects.According to the wishes of patients and their families,they were divided into an acupuncture group and a conventional group,with 71 cases in each group.On the basis of the treatment of primary diseases,the acupuncture group was treated with traditional Chinese medicine acupuncture at relevant acupoints.The conventional group was treated with Mosapride on the basis of the treatment of the primary disease.The gastric emptying time (GET),antral contraction frequency (ACF),antral motility index (MI) and intestinal peristalsis before and during treatment were compared between the two groups,and the defecation time,length of ICU stay,total hospitalization cost and mortality were compared between the two groups.Results The GET after 7 days of treatment in the two groups were shorter than those after 5 days of treatment,the GET after 5 days of treatment in the two groups were shorter than those after 3 days of treatment,and the GET after 3 days of treatment in the two groups were shorter than those before treatment,and the differences were statistically significant(P＜0.05).The GET at 3,5 and 7 days of treatment in the acupuncture group were shorter than those in the conventional group,and the differences were statistically significant (P＜0.05).The ACF of the two groups after 7 days of treatment were faster than those after 5 days of treatment,the ACF after 5 days of treatment were faster than those after 3 days of treatment,and the ACF after 3 days of treatment were faster than those before treatment,and the differences were statistically significant(P＜0.05).The ACF of the acupuncture group at 3,5 and 7 days of treatment were faster than those of the conventional group,and the differences were statistically significant (P＜0.05).The MI of the two groups after 7 days of treatment were higher than those after 5 days of treatment,and the MI of the two groups after 5 days of treatment were higher than those after 3 days of treatment,and the differences were statistically significant (P ＜0.05).The MI of the acupuncture group after 3 days of treatment was higher than that before treatment,and the difference was statistically significant (P＜0.05).The MI of the acupuncture group were higher than those of the conventional group at 3,5 and 7 days after treatment,and the differences were statistically significant(P＜0.05).The intestinal peristalsis of the two groups after 7 days of treatment were faster than those after 5 days of treatment,and the intestinal peristalsis of the two groups after 5 days of treatment was faster than those after 3 days of treatment,and the differences were statistically significant (P＜0.05).The intestinal peristalsis of the acupuncture group after 3 days of treatment was faster than that after 1 day of treatment,and the intestinal peristalsis of the acupuncture group after 1 day of treatment was faster than that before treatment,and the differences were statistically significant (P＜0.05).After 1,3,5 and 7 days of treatment,the intestinal peristalsis of the acupuncture group were faster than those of the conventional group,and the differences were statistically significant(P＜0.05).The defecation time of the acupuncture group was shorter than that of the conventional group,the total hospitalization cost was less than that of the conventional group,and the mortality rate of the acupuncture group was lower than that of the conventional group on the 10th to 42nd day after treatment,and the differences were statistically significant (P ＜0.05).Conclusion Mosapride has a certain effect on gastrointestinal dysfunction in severe patients,but traditional Chinese medicine acupuncture treatment through Neiguan,Hegu,Zhongwan,Tianshu,Qihai,Zusanli,Fenglong,Sanyinjiao and other acupoints has a definite effect on gastrointestinal dysfunction in severe patients.The benefits of traditional Chinese medicine acupuncture treatment for gastrointestinal dysfunction in severe patients are greater than Mosapride treatment.It can shorten the gastric emptying time,increase the amplitude of gastric antrum movement and intestinal peristalsis,improve MI,improve gastrointestinal dysfunction earlier,reduce the total cost of hospitalization,and improve the prognosis of patients.

Objective To evaluate the safety and effectiveness of Yiqi-Yangyin-Huoxue-Lishui combined with Conbercept in the treatment of diabetic macular edema(DME),and to provide more clinical means and ideas for the treatment of DME by the combination of traditional Chinese and Western medicine.Methods A total of 70 DME patients hospitalized in the Department of Ophthalmology,Pingxiang People's Hospital from June 2019 to June 2022 were selected as the research objects.Monocular drug injection was performed in each treatment cycle,only one eye was enrolled in the study.Six patients were followed up,and 64 patients were included in the statistics.They were divided into treatment group (29 cases)and control group(35 cases)according to admission.The treatment group was given intravitreal injection of Compaercept once combined with oral Yiqi-Yangyin-Huoxue-Lishui Chinese medicine set for 3 months.The control group was given intravitreal injection of Compacept once.The best corrected visual acuity (BCVA),central retinal thickness (CRT),traditional Chinese medicine syndrome score and the number of repeated intraocular drug injection were compared between the two groups before treatment and 1,3 and 6 months after treatment.Results The comparison of BCVA,CRT and traditional Chinese medicine syndrome score before and after treatment between the two groups showed statistically significant differences (P＜0.05),while the comparison of BCVA,CRT and traditional Chinese medicine syndrome score between the two groups and their interaction before and after treatment showed no statistically significant differences (P＞0.05).BCVA,CRT and traditional Chinese medicine syndrome score of the treatment group 1 and 3 months after treatment and the control group 1 month after treatment were higher than those before treatment,and the differences were statistically significant (P＜0.05).There was no significant difference in BCVA,CRT and traditional Chinese medicine syndrome scores 3 months after treatment in the control group and 6 months after treatment in the two groups (P＞0.05).CRT at 3 months after treatment rebounded compared with 1 month after treatment.Five cases in the treatment group needed to be re-injected with Compaplomb,less than 15 cases in the control group,and the difference was statistically significant (χ2=4.844,P=0.033).Compared with the average changes of BCVA,CRT and traditional Chinese medicine syndrome score before treatment,the improvement of BCVA,CRT and traditional Chinese medicine syndrome score in the treatment group was always better than that in the control group.In addition,no significant safety issues occurred during treatment in either group.Conclusion The efficacy of Yiqi-Yangyin-Huoxue-Lishui combined with Conbercept in the treatment of DME may be better than that of Conbercept alone,which is helpful to improve postoperative BCVA ands delay the recurrence of macular edema.

 Objective To investigate the effect of Adjusted Qingre Jiedu Formula (AQJF)on the pregnancy outcome of infertility patients caused by chronic endometritis(CE).Methods A total of 265 patients with infertility caused by CE admitted to the outpatient department of Jiangxi Maternal And Child Health Hospital from October 2020 to October 2021 were selected as the study objects.They were divided into study group (93 cases)and control group (172 cases)according to the treatment methods.The study group was treated with AQJF combined with antibiotics,and the control group was treated with conventional antibiotics.The general conditions (age,type of infertility,duration of infertility,body mass index,endometrial thickness on implantation day,number of transferred embryos,etc.),hysteroscopy review after treatment,histopathological examination results and pregnancy outcomes(embryo implantation rate,clinical pregnancy rate and adverse pregnancy rate)were compared between the two groups.Results The negative conversion rate of cluster differentiation (CD)138 and CD38,embryo implantation rate,and clinical pregnancy rate in the study group were higher than those in the control group,and there was no significant difference in the adverse pregnancy rate of the two groups.Conclusion AQJF combined with antibiotics can improve uterine cavity environment and pregnancy outcome in patients with CE,and the effect is better than that of antibiotics alone.

Objective To explore the effect of Suhexiang Pills combined with Sodium Butylphthalide Chloride on improving the prognosis of patients with cerebral infarction.Methods A total of 100 patients with acute cerebral infarction (ACI)admitted to Jiujiang Traditional Chinese Medicine Hospital from March 2021 to March 2023 were divided into control group(50 cases)and a treatment group (50 cases)according to the random number table method.The control group patients were treated with aspirin or clopidogrel,while the treatment group patients were treated with Suhexiang Pills and Sodium Butylphthalide Chloride Injection for a total of 14 days.The clinical efficacy,symptom improvement,coagulation function,inflammatory cytokine levels,neurological function,complications,and safety were compared between two groups of patients.Results The total effective rate of the treatment group was higher than that of the control group,and the symptom score,National Institute of Health stroke scale (NIHSS),D-dimer (D-D),fibrinogen (FIB),interleukin-6 (IL-6),and interleukin-8(IL-8)levels of the two groups after treatment were all lower than those before treatment in the same group,and these indexes the treatment group were lower than the control group,and the differences were statistically significant(P＜0.05).The total incidence of complications in the treatment group was lower than that in the control group,and the difference was statistically significant (P＜0.05).There was no statistically significant difference in the adverse reactions between the two groups(P＞0.05).Conclusion The overall effect of Suhexiang Pills combined with Sodium Butylphthalide Chloride in the treatment of ACI is definite,which can exert anticoagulation,reduce inflammatory reactions,promote neurological function recovery,and has fewer complications and good safety.It is worth promoting.

Objective To explore the clinical efficacy of ultrasound-guided pain point injection combined with traditional Chinese medicine massage treatment for patients with iliopsoas muscle injury.Methods A total of sixty patients with iliopsoas muscle injury admitted to the Fifth People's Hospital of Ganzhou from January 2021 to March 2023 were selected as the study objects.They were divided into control group (30 cases) and observation group (30 cases) according to the random number table method.The control group received traditional lumbar and leg massage and ultrasound guided pain point injection of Danhong injection,while the observation group received ultrasound guided pain point injection and traditional Chinese medicine massage.The Oswestry dysfunction index (ODI)and Visual analog scale (VAS),clinical symptom relief time,total effective rate,and overall satisfaction of the two groups of patients were compared.Results There were no statistically significant differences in ODI scores between the two groups before and 1 day after treatment (P＞0.05).The ODI scores of the observation group patients were lower than those of the control group at 7 days,1 month,6 months after treatment,and the differences were statistically significant (P＜0.05).The ODI scores of the two groups of patients were lower than those of the same group before treatment at 1 days,7 days,1 month,6 months after treatment,and the differences were statistically significant(P＜0.05).After treatment,the VAS scores of the two groups were lower than those of the same group before treatment,and the VAS score of the observation group after treatment was lower than that of the control group,and the differences were statistically significant(P＜0.05).After treatment,the clinical symptom relief time in the observation group was shorter than that in the control group,and the total effective rate and satisfaction were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Ultrasound guided pain point injection combined with traditional Chinese medicine massage can significantly alleviate body pain in patients with iliopsoas muscle injury,improve lumbar muscle function,and have a significant therapeutic effect,which can be promoted.

Objective To analyze the research hotspots and development trends of horizontal violence in nurses based on the Web of Science database.Methods Literature related to horizontal violence in nurses was retrieved from the Web of Science core collection database from the establishment of the database until 17:00 on December 31,2022.The characteristics of the literature were explored.Histcite 1.0,VOSviewer 1.6.1,CiteSpace 5.5 and SPSS 20.0 software were used for bibliometrics analysis,and knowledge map was drawn.Results A total of 71 literatures related to nursing lateral violence were retrieved in this study,the number of publications was the largest in the United States,and some institutions cooperated closely.The first study on lateral violence in professional nurses was published in 2003,and 2015 and 2016 were the periods with the highest number of publications on lateral violence in nursing.The research focuses on three aspects:the generation,negative influence and coping style of lateral violence in nursing.Conclusion In recent years,the development of nursing lateral violence has been slow.In the future,relevant researchers should strengthen the research on the promotion of nursing safety cultural environment,the prevention of nursing lateral violence,the reform of nursing education and the theoretical explanation of nursing lateral violence,so as to ensure the healthy and sustainable development of nursing service industry.

 Objective To understand the incidence of adolescent idiopathic-scoliosis (AIS)among Qingyuan City through screening.Methods A total of 665 333 adolescents in Qingyuan city from September 2021 to September 2022 were selected as the research subjects.AIS screening was performed by"three-check method"and"five-step screening method"in terms of gender,age,cobb angle,age distribution,and the survey results were statistically analyzed.Results A total of 3 122 cases of AIS were detected by the"five-step screening method",the detection rate was 0.5% (3 122/665 333),and the detection rate was 54.6%(1 704/3 122)for males and 45.4%(1 418/3 122)for females.There was no significant difference in detection rate between male and female (P＞0.05).A total of 1 824 cases of AIS were detected by the"three detection method",with an incidence rate of 0.3%(1 824/665 333),including 801 males with an incidence rate of 0.2%,and 1 023 female with an incidence of 0.3%.There was no significant difference in incidence between male and female (P＞0.05).AIS was concentrated in 10 to 18 years old,and the prevalence rate was highest in 14 to 16 years old,and the number of Cobb angles in 10° to 20° was the most.Conclusion By conducting adolescent scoliosis screening,it can effectively detect scoliosis early and improve the physical health level of adolescents.

Objective To analyze the level of hope and related risk factors in patients with type 2 diabetes (T2DM).Methods A total of 94 T2DM patients admitted to the First People's Hospital of Fuzhou from June 2021 to September 2022 were selected as the study objects.Herth hope index(HHI)was used to assess the patients'hope level,the general data questionnaire and social support scale were used to evaluate,the HHI score of T2DM patients with different characteristics and social support were compared,the risk factors affecting hope level in T2DM patients were analyzed.Results The HHI score of 94 patients with T2DM was（33.65±4.58）.There were statistically significant differences in HHI scores among different families with per capita monthly income,disease course,complications,social support and coping styles(P＜0.05).Multiple linear regression analysis showed that low family per capita monthly income(t=3.948),long course of disease(t=3.124),complications(t=6.042),low social support(t=2.731)and negative coping disease(t=3.073)were the risk factors affecting hope level of T2DM patients (P＜0.05).Conclusion The hope level of T2DM patients is medium and affected by many risk factors.Clinical attention should be paid to patients with risk factors,and early targeted nursing intervention should be actively carried out to improve the psychological state of patients,adjust their emotions and improve the hope level.

Objective To analyze the related influencing factors of home rehabilitation in elderly patients with hip fracture after operation.Methods A total of 87 elderly patients with hip fracture surgery admitted to the Second People's Hospital of Yichang from January to December 2021 were selected as the research objects.The general information and family support of the research objects were collected through questionnaires,the home rehabilitation situation was evaluated,and the related influencing factors was analyzed.Results Among the 87 patients,59 cases were evaluated as excellent group and 28 cases were evaluated as general group.The results of single factor analysis showed that there were no significant difference in gender,age,education,caregiver status during home rehabilitation and financial support from children between the two groups(P＞0.05).There were statistically significant differences in the personal monthly income level,the number of chronic diseases,the daily care length of caregivers,and the rehabilitation exercise encouraged by caregivers between the two groups(P＜0.05).Multivariatelogisticanalysisshowedthatpersonalincome＜2400yuan(β=1.386,OR=4.000,95%CI=1.169-13.692),number of chronic diseases ≥2 kinds (β=1.913,OR=6.771,95%CI=2.087-21.962) and daily care duration of caregivers ＜4.76 h (β=1.259,OR=3.523,95%CI=1.080-11.493)were risk factors for home rehabilitation of elderly patients with hip fracture(P＜0.05).Rehabilitation exercise encouraged by caregivers(β=-1.851,OR=0.157,95%CI=0.043-0.573)was a protective factor for home rehabilitation in elderly patients with hip fracture (P＜0.05).Conclusion According to the related factors affecting the rehabilitation of elderly patients with hip fracture at home,caregivers should strengthen the care and encouragement of patients,pay attention to the harm of chronic diseases to the rehabilitation of patients,so as to promote the rehabilitation of elderly patients.

Since 2018,the "4+7" centralized procurement organized by the state has gradually started,and then China's centralized procurement has been continuously promoted in terms of point,area,scale,and level.It adopts the methods of"procurement with quantity,price in exchange for quantity,integration of procurement and bidding,ensuring use,ensuring quality,ensuring supply,ensuring payment,reducing transaction costs",etc.,to provide patients with high-quality and affordable pilot drugs,so that the reform results can benefit more people.Through optimizing relevant policies and measures,it can ensure the long-term stable supply of selected drugs,guide the healthy,orderly and high-quality development of the pharmaceutical industry.However,there are still some problems that need to be solved in the management of centrally procured drugs.This article analyzes the practice of drug centralized procurement management in a tertiary hospital in Changzhou,introduces a new management model of fine management,emphasizes management processes and details,in order to eliminate waste and redundant links in management,focuses on the formulation and implementation of relevant measures,system updates,and information support,and shares it for medical institutions to refer to.

 Objective To explore the effect of standardized management of crash carts in the model of the National Regional Medical Center.Methods A total of 40 crash carts in Liuzhou Hospital of Guangzhou Women and Children's Medical Center were modified according to the standardized management model of first-aid medicine and special skill training was conducted for all medical staff in the hospital.The number of varieties,amount,proportion of reported drug loss,time of taking medicine and accuracy rate of the drug catalog in the crash carts were compared before(October 2022 to March 2023)and after (April to September 2023)the optimization.And the questionnaire was used to investigate whether the optimized drug varieties met the rescue needs.Results The time of taking medicine in the observation group was shorter than that in the control group,and the accurate rate of taking medicine in the observation group was higher than that in the control group,the difference was statistically significant(P＜0.05).There was no significant difference among different working years in the observation group (P＞0.05),the optimized drug varieties met the rescue needs.Conclusion The standardized management model with the crash carts under the model of the National Regional Medical Center has remarkable effect,which is worth to be widely implemented.

With the increasing aging of the population,the number of elderly patients in clinical work is increasing.How to protect the health and rights of the elderly is an urgent problem in clinical work.In clinical diagnosis and treatment,in the face of elderly patients,it is an extremely complicated process to inform anesthesia methods and risks,master communication skills,strengthen humanistic care,extend the time of anesthesia talks,and increase the number of anesthesia talks.When the elderly patient has decision-making ability,the patient and the family do not agree,the anesthesiologist should respect the patient's own will.However,when the patient does not have the ability to make independent decisions,the patient's family members or their agents need to exercise their informed consent on behalf of the patient,following the principle of maximizing the interests of the patient and minimizing the risks.Informed consent is an ongoing process,not a single event,and may require repeated discussions and confirmations,and records at each stage to achieve true informed consent,thereby protecting the rights and interests of elderly patients.

 Objective To explore the practical effects of incorporating diverse teaching methods with elements of traditional Chinese medicine ideology into pediatric nursing courses at higher-level traditional Chinese medicine institutions.Methods A total of 429 students from Anhui University of Chinese Medicine in 2019 were selected as the study group,and 432 students from Anhui University of Chinese Medicine in 2018 were selected as the control group.The control group adopted the conventional classroom teaching method in pediatric nursing teaching,while the research group combined the characteristics of the discipline,the characteristics of nursing students and the characteristics of traditional Chinese medicine culture in pediatric nursing teaching,and adopted the diversified teaching method integrating traditional Chinese medicine thinking and politics.The teaching feedback of the two groups was compared.Results Following the integration of elements of traditional Chinese medicine ideology into the diversified teaching of the pediatric nursing course,97.4%of students reported a noticeable increase in the teacher's affinity,positive guidance,and the atmosphere of traditional Chinese medicine culture.Additionally,99.3%of students considered gaining knowledge and skills in both traditional Chinese and Western medicine as the most satisfying aspect.Moreover,97.2%of students actively utilized resources to complete educational tasks.Students generally believed that their abilities for independent learning,interest in professional courses and traditional Chinese medicine,as well as their career beliefs and planning,showed significant improvement compared to the control group,with statistically significant differences (P＜0.05).Teachers expressed that the teaching had more distinctive features of traditional Chinese medicine and was beneficial for nursing undergraduates to adapt to the clinical demands and professional values of both traditional Chinese and Western medicine.Conclusion Incorporating diverse teaching methods with elements of traditional Chinese medicine ideology into pediatric nursing courses can effectively enhance the efficiency of learning traditional Chinese medicine and professional knowledge.It also guides students in understanding the status of nursing as a profession,its societal value,and the role of traditional Chinese medicine in health maintenance.This approach contributes to the stability of the nursing workforce and the overall improvement of their comprehensive qualities.

Respiratory therapy is a professional and practical subject,which develops rapidly.The traditional teaching model can not meet the training needs of respiratory therapy professionals.The blended teaching,which combines the advantages of Internet teaching and traditional teaching mode,is an important direction of the current teaching reform in colleges and universities.In the past,it was believed that for clinical courses,online education has a single teaching method,lack of supervision and lack of interaction between teachers and students,and it is difficult to achieve good teaching results.With the rapid development of the Internet,online education platforms have developed rapidly.Cloud classroom,as a new online education model,breaks the time-space boundary of traditional classroom,uses information technology to provide teaching resources,guides students to learn independently and supports two-way interaction between teachers and students,and is increasingly applied in college education.The case-based learning(CBL)based on typical clinical cases can improve students' ability to integrate knowledge and analyze clinical problems,and has achieved good results in clinical course teaching.The course of respiratory therapy is basic and practical.In practical teaching,it explores the application of mixed teaching mode,combines case teaching with modern information transfer carriers such as cloud classroom,designs the learning baseline,and makes reasonable course planning.Make teaching videos and arrange online learning.Prepare clinical cases,practice teaching in class.Extension of materials after class to expand clinical thinking.Teaching modules such as courses and assessment are helpful for students to master basic theories and improve professional skills.

 Objective To analyze the influence of wechat platform combined with case-based learning (CBL)teaching on students'clinical thinking ability in medical oncology nursing teaching.Methods Thirty-three cases of nursing students who were practiced in the Department of Medical Oncology,Shandong Affiliated Hospital of Weifang Medical University from January 2022 to June 2022 were selected as the control group,and routine teaching was carried out.Thirty-three cases of nursing students who were practiced in the Department of Medical Oncology,Shandong Affiliated Hospital of Weifang Medical University from July 2022 to January 2023 were selected as the observation group,and wechat platform combined with case-based learning(CBL)teaching was given.The clinical thinking ability and comprehensive quality ability of nursing students in the two groups were compared.Results After teaching,the assessment scores of theoretical knowledge and practical skills of nursing students in the observation group were higher than the control group,and the differences were statistically significant (P＜0.05).The scores of clinical thinking ability in the two groups were higher than those in the control group,and the scores of clinical thinking ability and the comprehensive quality and ability assessment form for clinical practice of nursing students after the teaching were higher than the control group,and the differences were statistically significant (P＜0.05).Conclusion The application of wechat platform combined with CBL teaching in the teaching of medical oncology nursing can achieve remarkable results,which can not only improve the graduation results of nursing students,but also enhance their clinical thinking ability and comprehensive quality ability.

] Objective To investigate the effect of comfort nursing on the adverse reactions and satisfaction of patients with diabetic nephropathy treated by maintenance hemodialysis.Methods A total of 80 diabetic nephropathy maintenance hemodialysis patients admitted to Xingguo Hospital Affiliated to Gannan Medical University from August 2021 to August 2023 were selected as the study objects,they were divided into control group (n=40) and observation group (n=40) by random number table method.The control group received routine nursing,while the observation group received comfort nursing.The score changes of renal function(serum creatinine[SCr],blood urea nitrogen[BUN]),adverse mood(self-rating anxiety scale[SAS],self-rating depression scale[SDS])and quality of life(short form 36 health survey questionnaire[SF-36])were compared between the two groups before and after nursing,adverse reactions were compared between the two groups,and nursing satisfaction was observed between the two groups.Results The BUN,SCr level,SAS and SDS score of the observation group were lower than those of the control group after nursing,and the differences were statistically significant(P＜0.05).The SF-36 score was higher than that of the control group,and the difference was statistically significant (P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and nursing satisfaction was higher than that in the control group,with statistically significant difference(P＜0.05).Conclusion Comfort nursing for diabetic nephropathy maintenance hemodialysis patients has significant effects,which can improve renal function,improve bad mood,improve quality of life,reduce the risk of adverse reactions in diabetic nephropathy patients,and have high nursing satisfaction,which is worthy of promotion.

Objective To investigate the effect of"one disease,one product"mode in patients with hepatic carcinoma undergoing transcatheter artery chemoembolization (TACE).Methods A total of 100 patients with liver cancer admitted to Jiangxi Cancer Hospital from September 2021 to September 2023 were selected as research objects,and they were divided into two groups with 50 patients in each group by random number table method.The control group was treated with routine nursing,and the observation group was treated with "one disease,one product" mode,continuous intervention until discharge.The psychological state,pain,self-care ability,complication rate and quality of life of the two groups were compared.Results The scores of self-rating anxiety scale(SAS),self-rating depression scale(SDS),numerical rating scale (NRS) and total complication rate in the observation group were lower than those in the control group,and the scores of self-care ability assessment scale and World Health Organization quality of life (WHOQOL) scale were higher than those in the control group,the differences were statistically significant (P＜0.05).Conclusion The"one disease,one product"mode can alleviate the bad mood and pain of patients undergoing TACE for liver cancer,promote the improvement of self-care ability and quality of life,and reduce the risk of complications.

Objective To explore the effect of narrative nursing on anxiety,depression and quality of life in rectal cancer patients with preventive colostomy.Methods A total of 96 rectal cancer patients with preventive colostomy admitted to the Department of Colorectal and Anal Surgery,Affiliated Tumor Hospital of Guangxi Medical University from July 2020 to June 2022 were selected as the research objects.According to the random number table method,the patients were divided into routine nursing group (48 cases)and narrative nursing group (48 cases).Patients in routine nursing group received routine nursing,while patients in narrative nursing group received narrative nursing in addition to routine nursing.The negative emotional status and quality of life of the two groups were compared.Results After nursing,the anxiety score and depression score of the narrative nursing group were lower than those of the routine nursing group,and the differences were statistically significant(P＜0.05).After nursing,the quality of life scores of physical function,role function,cognitive function,emotional function and social function in the narrative nursing group were higher than those in the routine nursing group,and the differences were statistically significant(P＜0.05).The total nursing satisfaction of the narrative nursing group was higher than that of the routine nursing group,and the difference was statistically significant(P＜0.05).Conclusion Narrative nursing for rectal cancer patients with preventive colostomy can improve their postoperative mental state,quality of life and satisfaction with hospitalization nursing.

Objective To observe the nursing effect of modified Baxie exercises combined with heat-sensitive moxibustion on autologous arteriovenous fistula(AVF)in uremia patients.Methods A total of 80 uremic patients who underwent autologous AVF plasty in the Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine from August 2020 to February 2022 were selected as the research objects.According to the random number method,they were divided into the control group(40 cases)and the observation group(40 cases).Patients in the control group were given routine postoperative nursing,while patients in the observation group were given modified Baxie exercise combined with heat-sensitive moxibustion on the basis of the control group.Both groups were intervened for 12 weeks.The maturity of internal fistula and the use of arteriovenous fistula were compared between the two groups.Results At 8 and 12 weeks after operation,the physical maturation rate and ultrasonic maturation rate of the observation group were higher than those of the control group,the venous inner diameter of the observation group was longer than that of the control group,the venous skin depth was shorter than that of the control group,and the venous blood flow was higher than that of the control group,and the differences were statistically significant (P＜0.05).The first puncture time of the observation group was shorter than that of the control group,the success rate of the first puncture was higher than that of the control group,and the incidence of complications within 6 months after operation was lower than that of the control group,and the differences were statistically significant (P＜0.05).Conclusion The application of modified Baxie exercises combined with heat-sensitive moxibustion has a positive effect on the nursing of AVF in uremia patients,which can improve the blood flow of internal fistula,shorten the ripening time,improve the puncture success rate and reduce the incidence of complications.

Objective To explore the effect of reflective cycle model combined with explication-simulation-exercise-communication-support(ESPCS)intervention in self-management of chronic obstructive pulmonary disease (COPD).Methods A total of 90 COPD patients admitted to Jiujiang NO.1 People's Hospital from July 2021 to May 2023 were selected as the research objects.They were divided into control group and study group by random number table method,with 45 cases in each group.The control group received routine nursing,and the study group received reflective cycle model combined with ESPCS nursing intervention.The changes of self-management behavior and mental state were compared between the two groups.Results Before intervention,there were no significant differences in self-management behavior scale scores between the two groups (P＞0.05).After intervention,the self-management behavior score of the study group was higher than that of the control group,and the difference was statistically significant (P＜0.05).Before intervention,there were no significant differences in self-rating anxiety scale (SAS)and self-rating depression scale (SDS)scores between the two groups (P＞0.05).After intervention,the scores of SAS and SDS in the study group were lower than those in the control group,and the differences were statistically significant (P＜0.05).Conclusion Reflective cycle model combined with ESPCS intervention can effectively improve the self-management ability and attention of COPD patients,and actively adjust their diet,rest,rehabilitation exercise and living habits,improve bad mood,and help improve the quality of life of patients,and can be further promoted in clinical application.

Objective To investigate the effect of alginate dressing on the separation of stoma skin and mucosa after enterostomy surgery.Methods A total of sixty patients with enterostomy separation from October 2020 to October 2021 admitted to Ji'an Central People's Hospital were selected as the study objects,which were divided into observation group(30 cases)and control group (30 cases)according to the random number table method.Among them,targeted care was gaved to the control group,and the observation group was treated with alginate dressing on the basis of the control group to compare the incision healing,total incidence of complications and total nursing satisfaction between the two groups.Results The stoma leakage volume of the observation group was less than the control group,and the healing time and the clearing time of the observation group were shorter than the control group,and the differences were statistically significant (P＜0.05).The total incidence of complications of the observation group was lower than the control group,and the difference was statistically significant (P＜0.05).The overall nursing satisfaction of the observation group was higher than the control group,and the difference was statistically significant (P＜0.05).Conclusion For patients with enterostomy surgery treatment after stoma skin mucosa separation problem,take alginate dressing combined targeted nursing intervention,can speed up the stoma healing,reduce the exudation,and can reduce the complication rate in patients,improve the prognosis safety,meet the demand of the physical and mental intervention,patients nursing satisfaction is higher,is worth promoting.

In recent years,the problem of adolescent scoliosis in China has become increasingly serious.According to statistics,more than five million adolescents are already suffering from scoliosis.Idiopathic scoliosis,as the most common type,has a relatively high incidence.In the face of such situations,we must attach great importance to scoliosis screening and take corresponding interventions.Early detection and treatment of the disease is crucial to the recovery and quality of life of patients,such as early detection and early treatment,the recovery outcome is relatively good,can effectively slow or avoid the deterioration of the disease,and the appearance of irreversible deformities.This research systematically reviews the relevant studies and literatures,summarizes the research progress in the field of adolescent idiopathic scoliosis(AIS)screening at home and abroad,reviews the current commonly used AIS screening methods,including forward flexion test,evaluation of trunk rotation angle,anthropometric tools and imaging examination,and elaborates and analyzes the characteristics of each method.At present,the forward flexion test combined with the evaluation of the trunk rotation angle is the most commonly used screening method,which is simple,easy to perform,economical and practical.

Organizing pneumonia (OP)is a kind of lung disease with the presence of inflammatory fibrous thrombus in the distal air cavity as the main pathological manifestation.According to etiology,OP can be divided into cryptogenic organizing pneumonia(COP)and secondary organizing pneumonia(SOP).In view of the differences between COP and SOP in treatment and management,early diagnosis of them is extremely important.OP includes the process of injury,organization and reconstruction.The cause of COP is still unknown.The causes of SOP include drugs,infection,connective tissue diseases and so on.COP and SOP are not specific in clinical manifestations,and retrospective laboratory examination is of great reference value for SOP to inquire about the cause.The typical CT manifestations are multifocal consolidation,and the atypical manifestations are diverse,so it is necessary to pay attention to the differential diagnosis of other diseases.Pathohistology is the main criterion for the diagnosis of OP,including classical and special types (acute fibrinous OP and cicatricial OP),and its characteristics can correspond to the imaging mode and provide clues for the inquiry of the cause of SOP.It is very important for the diagnosis and management of COP and SOP that multidisciplinary teams synthesize clinical,laboratory,imaging and pathological information.

Post-stroke aphasis(PSA)is an acquired communication disorder caused by brain injury,which is characterized by multiple dysfunctions in spontaneous speech,repetition,naming,auditory comprehension,reading and writing,etc.As one of the serious sequelae of stroke,PSA has been found to seriously affect the quality of life of patients.It has been shown that early speech therapy intervention can restore the patient's ability to communicate functionally to a certain extent.A variety of rehabilitation techniques have been applied to the clinical treatment of PSA.This article summarized the traditional PSA treatment methods and new PSA therapies in this study by reviewing the relevant literature at domestic and abroad.Among them,traditional PSA treatments are mainly introduced as compulsory induced aphasia treatment,multimodal aphasia treatment,music therapy,acupuncture therapy,social therapy,medication and other therapies.The new PSA treatment techniques that emerged in recent years mainly involve therapies such as non-invasive brain stimulation,tele-rehabilitation,virtual reality,hyperbaric oxygen therapy,and photobiomodulation.The above literature was reviewed to further clarify the effectiveness of different intervention methods in the treatment of PSA and to provide more evidence to support the clinical diagnosis and treatment of PSA.

Cardiorenal syndrome(CRS)refers to the simultaneous acute or chronic dysfunction of the heart and kidney,resulting in a series of chain reactions and mutual damage to the heart and kidneys,with high morbidity and mortality.Currently,there are mainly 5 types of CRS in clinical practice,and different CRS have different pathogenic mechanisms and great differences in phenotypes.Despite significant advances in basic research and integrated management of heart failure(HF)and chronic kidney disease (CKD)in recent years,representative randomized controlled landmark studies in CRS are insufficient,and the treatment of these patients is mainly inferred from the corresponding HF or CKD trials.There is no effective treatment for CRS.With the advancement of healthcare technology and aging population,CRS has received increasing attention,and it is increasingly important to conduct the best assessment and management of CRS patients according to the latest research results.This article reviews the latest research results at home and abroad,and reviews the latest progress in the diagnosis,pathogenesis and clinical treatment of CRS.

 Diabetic kidney disease is one of the most common complications of diabetes mellitus and a common cause of end-stage renal disease.Genetic factors,metabolic disorders,oxidative stress,and inflammatory responses are closely related to the occurrence and development of diabetic kidney disease,but its pathogenesis is still unclear.Short-chain fatty acids are the main metabolites of dietary fiber fermented by intestinal flora in the host intestine.They participate in a series of metabolic processes,such as regulating appetite,regulating glucose metabolism,regulating lipid metabolism,and reducing inflammatory responses by activating G protein-coupled receptors and deacetylhistone receptors,and thus may play a key role in the occurrence and development of diabetic kidney disease.This article discusses the relationship between short-chain fatty acids and diabetic kidney disease and related controversies,in order to provide new ideas for understanding the role of short-chain fatty acids in the occurrence and development of diabetes and the prevention and treatment of diabetic kidney disease.