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Quick Search     Adv Search 2022 Vol. 29, No. 24 Published: 2022-08-28   5 Characteristics and risk factors of coronary artery lesions in children with Kawasaki disease HUANG Li，WEN Xuefeng，TANG Xiaoyan，HU Bing，WU Junyong Objective To analyze the characteristics and risk factors of coronary artery lesions (CAL) in children with Kawasaki disease (KD), so as to provide a basis for clinical treatment and prognosis. Methods The relevant clinical data of 180 children with KD admitted to the Pediatrics Department, Yichun People′s Hospital from January 2020 to May 2021 was retrospectively analyzed. According to the presence or absence of CAL, the children were divided into observation group (combined CAL, 31 cases) and control group (non-CAL, 149 cases). Both groups were treated with intravenous gamma globulin (IVIG). Gender, age, and the start time of using IVIG were collected. Multivariate logistic analysis was performed on the data with statistical differences in univariate analysis to screen the risk factors for CAL in children with KD. Results Univariate analysis showed that age, start time of using IVIG, IVIG resistance, erythrocyte sedimentation rate (ESR), duration of fever, treatment time, C-reactive protein (CRP), alanine aminotransferase (ALT),interleukin-6 (IL-6), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and serum sodium, decreased white blood cells (WBC), neutrophil-to-lymphocyte ratio (NLR) and platelet (PLT) were compared between two groups, the differences were statistically significant (P<0.05). Multivariate logistic analysis showed that duration of fever (β=1.254,OR=3.504, 95%CI=1.272-9.653), NT-proBNP (β=0.708, OR=2.030, 95%CI=1.170-3.521), WBC (β=0.869, OR=2.385,95%CI=1.332-4.286), PLT (β=0.657, OR=1.929, 95%CI=1.361-2.734), ESR (β=1.037, OR=2.821, 95%CI=1.533-5.819), and NLR (β=0.946, OR=2.575, 95%CI=1.262-5.256) were independent risk factors for CAL in children with KD (P<0.05). Conclusion Duration of fever, NT-proBNP, WBC, NLR, PLT and ESR are risk factors for CAL in children with KD. Attention should be paid to above-mentioned indicators in clinical treatment, and effective treatment should be performed timely. 2022 Vol. 29 (24): 5-8-13 [Abstract] ( 23 ) HTML (1 KB)  PDF (925 KB)  ( 37 ) 9 Clinical analysis of 47 cases with pulmonary thromboembolism LI Dagang，KANG Le Objective This analysis was made to improve the recognition of pulmonary thromboembolism by investigating the clinical features and assisted examinations. Methods The clinical data of 47 patients with pulmonary thromboembolism diagnosed in the Department of Respiratory of East Medicine District of Linyi People′s Hospital from August 2018 to January 2020 were retrospectively analyzed. The age of onset, gender, underlying diseases or potential risk factors, clinical symptoms, electrocardiogram, cardiac ultrasound, computer tomographic pulmonary angiography (CTPA),blood gas analysis, troponin T (cTnT), N-terminal pro-brain natriuretic peptide (NT-proBNP), D-dimer results and other indicators were analyzed.Results The elderly who suffered from hypertension,operation,trauma, or fracture were more subject to pulmonary thromboembolism. Dyspnoea, cough, and chest pain were major symptoms. Among the 47 patients,87.2% patients had sinus tachycardia, 68.1% patients had elevated pulmonary arterial systolic blood pressure, 82.9%patients had elevated N-terminal pro-brain natriuretic peptide,all patients had abnormal D-dimer and CTPA,and 74.5%patients had hypoxemia. Hypocapnia was present in 55.3% of patients, and cTnT was above normal in 66% of patients.Conclusion With a variety of underlying diseases and potential risk factors, the elderly were at high risk of pulmonary embolism. An adoption of CTPA, and D-dimer detection methods, supplemented by blood gas analysis, cardiac ultrasound, and other examinations were strongly recommended to help risk stratification, accurate diagnosis, and treatment. 2022 Vol. 29 (24): 9-13 [Abstract] ( 26 ) HTML (1 KB)  PDF (555 KB)  ( 95 ) 14 Bibliometric analysis of pulmonary emphysema literature based on Science Citation Index Expanded Database and VOSviewer WANG Anni,WANG He,YU Xiangrong Objective From the perspective of bibliometrics, this paper visually presents and deeply analyzes the pulmonary emphysema-related papers included in Science Citation Index Expanded Database (SCIE) from 2010 to 2020,and provides references for pulmonary emphysema researchers in China. Methods Taking the "pulmonary emphysema"papers collected in the SCIE database from January 1, 2010 to December 31, 2020 as samples, bibliometric analysis was carried out from the aspects of publication year, national or regional distribution, research direction and hot spots,published journals, papers with high citation frequency and citation frequency, the clustering map was drawn by VOSviewer software. Results From 2010 to 2020, the SCIE database included a total of 7219 articles of "pulmonary emphysema", mainly academic papers, and the number of papers showed an overall increasing trend. The overall level of pulmonary emphysema research in European and American countries is relatively higher than in Asian countries such as China and South Korea.The research hotspots of emphysema mostly focus on the imaging and clinical manifestations of the disease. Conclusion The research of pulmonary emphysema is receiving more and more attention from researchers all over the world, and more and more scholars and scientific research institutions are engaged in pulmonary emphysema-related research. Compared with other countries in the world, the research of pulmonary emphysema in China is still at a relatively low level, and there is much room for development. 2022 Vol. 29 (24): 14-18-22 [Abstract] ( 30 ) HTML (1 KB)  PDF (942 KB)  ( 49 ) 19 Comparison of application effect of three therapies in Helicobacter pylori positive patients XU Chunbo Objective To explore the application effect of bismuth containing quadruple therapy, sequential therapy and concomitant therapy in Helicobacter pylori (Hp) positive patients. Methods A total of 127 patients with peptic ulcer and chronic gastritis treated in Tongzhou District People′s Hospital of Nantong city from March 2019 to March 2021 were selected as the research subjects. All patients were confirmed by gastroscopy and positive for Hp by 14C urea breath test. According to random number table method, they were divided into bismuth quadruple therapy group (n=43),sequential therapy group (n=42) and companion therapy group (n=42). Hp eradication rate, improvement of clinical symptoms and total incidence of adverse reactions were compared among three groups after treatment. Results The results of intentional analysis showed that the Hp eradication rates of the sequential therapy group, the bismuth quadruple group and the companion therapy group were 69.05%, 79.07% and 85.71%, respectively. There was no statistical significance in the Hp eradication rates of the three groups (P>0.05). According to the results of the protocol set, the Hp eradication rates of the sequential therapy group, the bismuth quadruple therapy group and the companion therapy group were 73.68%, 87.5% and 94.87%, respectively, and the difference of Hp eradication rates among three groups were statistically significant (P<0.05). The Hp eradication rate in the companion therapy group was higher than that in the sequential therapy group, and the difference was statistically significant (P<0.017). There was no statistical significance in symptom scores of the three groups before treatment (P>0.05). After treatment, the symptom scores of patients in the three groups were higher than before, the difference was statistically significant (P<0.05), but there was no statistically significant difference between the symptom scores of patients in the three groups (P>0.05). The total incidence of adverse reactions after treatment was 19.05% (8/42) in the sequential treatment group, 16.28% (7/43) in the bismuth quadruple therapy group and 38.1% (16/42) in the companion treatment group, respectively, and there was no significant difference in the total incidence of adverse reactions among the three groups (P>0.05). Conclusion Companion therapy had the best Hp eradication rate, and the three treatments had similar symptom improvement effects with high safety. 2022 Vol. 29 (24): 19-22 [Abstract] ( 25 ) HTML (1 KB)  PDF (541 KB)  ( 23 ) 23 Research progress on the mechanism of β-adrenergic receptor signaling pathway regulating myocardial fibrosis in heart failure WANG Xinting，LU Cheng，SHI Tianyun，ZHONG Yihang，LIU Yongming Myocardial fibrosis is closely related to heart failure. The development of heart failure is accompanied by pathological changes of myocardial fibrosis. Myocardial fibrosis refers to the excessive accumulation of collagen in myocardial tissue structure, which is the main manifestation of adverse myocardial remodeling. Myocardial remodeling can reduce tissue compliance, damage cardiac function, promote the occurrence of arrhythmia and accelerate the progress of heart failure. Abnormal β-adrenergic receptor (βAR) signaling pathway is an important feature of heart failure. βAR plays a fundamental role in the physiological regulation of myocardium. Over activation of βAR system can promote the fibrosis process of heart failure, induce fibroblast proliferation, collagen secretion, migration and transform into myofibroblast phenotype. In this paper, the role of βAR signaling pathway in myocardial fibrosis of heart failure and the relationship between β1AR, β2AR, β3AR and myocardial fibrosis were discussed, so as to provide the development of potential therapeutic strategies for effective targeting at the pathological mechanism of disease progression. 2022 Vol. 29 (24): 23-27 [Abstract] ( 27 ) HTML (1 KB)  PDF (559 KB)  ( 53 ) 28 Research progress in risk assessment of stress injury in critically ill patients WANG Yaping，WANG Chen，ZHU Yaqin，ZHANG Yaowen Critically ill patients often suffer from stress injury due to their condition, which in turn leads to prolonged hospital stay and increased fatality rate. Therefore, it is particularly important to do a good job in risk assessment,screen high-risk patients and implement corresponding preventive measures to prevent the occurrence of pressure injury. This paper reviews the risk factors and common nursing assessment techniques of stress injury in critically ill patients. Stress injury risk assessment scale, ultrasonic detection, infrared thermal imaging monitoring, subcutaneous humidity and percutaneous oxygen partial pressure monitoring and other assessment techniques were introduced. To summarize the assessment content, score, reliability and validity of common clinical risk assessment scales. At the same time, the working principle and nursing application of various monitoring technologies are introduced to evaluate their advantages and disadvantages as well as the accuracy of predicting the occurrence of pressure injury, so as to improve the effectiveness and reliability of early assessment of pressure injury and provide reference for subsequent research. 2022 Vol. 29 (24): 28-32 [Abstract] ( 34 ) HTML (1 KB)  PDF (581 KB)  ( 207 ) 33 Review ofthe complications of the donor site after fibular flap operation ZHOU Zhegang，ZENG Hui The surgery of free fibular flap is an important operative method for the bone and flab defects, nevertheless,we should pay more attention for the complications of donor site which brings by the surgery of free fibular flap. The early manifestations of osteofascial compartment syndrome include swelling, pain, movement disorders, etc. which must be highly vigilant. If subclinical compartment syndrome occurs, decompression treatment should be carried out in time,and debridement, secondary suture, skin grafting and skin flap transplantation should be used to actively treat it. For long-term complications such as motor dysfunction and ankle instability, should focus on prevention, optimize the methods of surgical incision and closure, make the detection and diagnosis early, active the treatment, and strengthen the training of functional rehabilitation. For complications such as flexion contracture of thumb toe, the tendon release and extension reconstruction surgery can be used effectively. In recent years, objectively methods of limb dysfunction evaluate have been reported, such as fibula muscle sensory examination, walking gait test, optical analysis, electrophysiological analysis of leg function, but the commonly used methods are the ankle lateral instability scoring system and Enneking legs function evaluation scale clinically. This article reviews the etiology, prevention and treatment of common donor site complications after free fibular flap surgery, and the later functional training of the complications. 2022 Vol. 29 (24): 33-36 [Abstract] ( 25 ) HTML (1 KB)  PDF (540 KB)  ( 30 ) 37 Research progress on the mechanism of treating sepsis related coagulation dysfunction by Fuzheng Huayu Method JIN Fengbin,LI Wenzhi,ZHENG Yanlong,WANG Dexing Sepsis is a systemic inflammatory syndrome, which is often accompanied by disorders of immune and coagulation function, and can lead to multiple organ injuries, thus endangering life. Coagulation disorder is an important part in the progression of sepsis. In addition to pathogen-induced coagulation activation, injury-related molecular patterns,neutrophil external trapping net, extracellular vesicles and glycocalyx injury can also lead to the occurrence of sepsis induced coagulation disorder. In recent years, it has been found that traditional Chinese medicine has certain advantages in the treatment of sepsis-induced coagulopathy. In particular, Fuzheng Huayu Method has shown a good regulating effect on the coagulation system. Therefore, this paper reviews the research results of Fuzheng Huayu Method applied to sepsis-induced coagulopathy. 2022 Vol. 29 (24): 37-40-49 [Abstract] ( 23 ) HTML (1 KB)  PDF (841 KB)  ( 127 ) 41 Analysis of risk factors associated with multiple drug-resistant organisms infection in patients of intensive care unit TIAN Wenwen，WANG Pengxiang，YU Weiming，ZHANG Qianwen，WANG Likun Objective To analyze the risk factors of multiple drug-resistant organisms (MDRO) infection in intensive care unit (ICU) patients of Liangshan People′s Hospital and the clinical distribution characteristics of multi-drug resistant bacteria. Methods A total of 159 patients with bacterial infection admitted to ICU from January 2016 to June 2021 were analyzed retrospectively as research objects, including 65 cases in the sensitive bacterial infection group and 94 cases in the MDRO group. A variety of intervention factors in the two groups were statistically analyzed, such as patients′ age, gender, time in the ICU, basic diseases, surgery, conscious state, variety of antibiotic use, glucocorticoid use time, endoheal intubation time, tracheotomy, mechanical ventilation time, time of urinary catheter, gastric catheter,vasoactive drugs, blood transfusion and other factors. Results The results of univariate analysis showed that there were significant differences of the incidence of underlying diseases, hemoglobin content, procalcitonin (PCT), C-reactive protein (CRP), types of antibiotics, tracheotomy time, mechanical ventilation time and vasoactive drug use time in the MDRO group compared with the sensitive bacteria group (P<0.05). The multivariate analysis showed that the underlying diseases (β=1.156, OR=3.178, 95%CI=1.404-7.195) and the type of antibiotics (β=0.69, OR=1.995, 95%CI=1.021-3.896) were independent risk factors for multi-drug resistant bacterial infection in ICU patients (P<0.05). Most of the MDRO infection were Acinetobacter baumannii (57.447%), Pseudomonas aeruginosa (7.447%), Klebsiella pneumoniae(7.447%) and mixed bacterial infection (15.957%). The infection was mainly distributed in the lung (89.362%), outside the lung (3.191%) (such as urinary system, abdominal cavity, soft tissue and intracranial, etc.) and mixed sites(7.447%). Conclusion MDRO hospital infection is closely related to underlying diseases, type of antibiotic used, clinical attention should be paid. 2022 Vol. 29 (24): 41-45 [Abstract] ( 22 ) HTML (1 KB)  PDF (460 KB)  ( 32 ) 46 Clinical effect of intravascular embolization treatment in patients with intracranial aneurysm complicated with cerebral infarction WANG Liang，WANG Gang，KONG Lingchun Objective To analyze the clinical effect of intravascular embolization in the treatment of intracranial aneurysm complicated with cerebral infarction. Methods A total of 70 patients with intracranial aneurysm complicated with cerebral infarction admitted to Affiliated Central Hospital of Shenyang Medical College from June 2018 to June 2021 were selected as the research objects. They were divided into control group and experimental group according to random number table method, with 35 cases in each group. The control group was treated with intracranial aneurysm clipping under microscope, and the experimental group was treated with intravascular embolization. The clinical effects of the two groups were compared. Results The total effective rate and the excellent and good rate of Alberta stroke program early CT (ASPECT score) in the experimental group were higher than those in the control group, the differences were statistically significant (P<0.05). After operation, the total incidence of new cerebral infarction foci and total adverse reaction rate in the experimental group were lower than those in the control group, and the differences were statistically significant (P<0.05). Conclusion Intravascular embolization can treat intracranial aneurysm complicated with cerebral infarction more effectively, with higher safety, it is worthy of clinical promotion. 2022 Vol. 29 (24): 46-49 [Abstract] ( 29 ) HTML (1 KB)  PDF (474 KB)  ( 100 ) 50 Effect comparison between laparoscopic and open hepatectomy in the treatment of hepatolithiasis LU Ziheng，WAN Dechen，ZHOU Dachen，ZHANG Bin Objective To compare the effect of laparoscopic and open hepatectomy in the treatment of hepatolithiasis.Methods From January 2016 to December 2020, a total of 122 patients with hepatolithiasis undergoing hepatectomy treated in the Second Affiliated Hospital of Anhui Medical University were selected as research subjects for retrospective analysis. They were divided into observation group (n=55) and control group (n=67) according to different surgical methods. Laparoscopic hepatectomy was performed in the observation group, while open hepatectomy was performed in the control group. The perioperative indicators, stone clearance rate, total incidence of postoperative complications and total effective rate were compared between the two groups. Results The operation time of the laparoscopic group was longer than that of the open group, and the removal time of the abdominal drainage tube and the length of stay were shorter than those of the open group, the differences were statistically significant (P<0.05). There were no significant differences in intraoperative blood loss, first ventilation time, transfusion rate, total postoperative complication rate,stone residual rate and total effective rate between the two groups (P>0.05). Conclusion Laparoscopic hepatectomy is safe and effective in the treatment of hepatolithiasis, with quicker recovery and shorter hospital stay than open hepatectomy. 2022 Vol. 29 (24): 50-53 [Abstract] ( 30 ) HTML (1 KB)  PDF (523 KB)  ( 15 ) 54 Application effect of modified Brisson operation in children with concealed penis LU Xusheng，WANG Mingqun Objective To investigate the effect of modified Brisson operation in children with concealed penis. Methods A total of 120 children with concealed penis treated in Puning People′s Hospital from March 2020 to April 2021 were selected as the research object. Children with concealed penis were randomly divided into control group and observation group, with 60 cases in each group. The control group was treated with conventional single valve insertion of inner and outer plates, and the observation group was treated with modified Brisson operation. Both groups were followed up for 1 month. The operation effect, quality of life before and 1 month after operation, complications 7 days after operation, and satisfaction 1 month after operation were compared between the two groups. Results Compared with the operation effect of the two groups, the edema recovery time and bandage dressing time in the observation group were shorter than those in the control group, the penis growth length was longer than that in the control group one month after operation, and the penis appearance score was higher than that in the control group, with statistically significant differences (P＜0.05). There was no significant difference in preoperative quality of life between the two groups (P＞0.05).Compared with the quality of life between the two groups one month after operation, the scores of self satisfaction, physical feeling and life convenience in the two groups were higher than those before operation, and the scores in the observation group were higher than those in the control group,with statistically significant differences(P＜0.05).The total incidence of complications 7 days after operation in the observation group was higher than that in the control group, and the difference was statistically significant (P＜0.05). The total satisfaction of the observation group one month after operation was higher than that of the control group,with a statistically significant difference(P＜0.05).Conclusion The modified Brisson operation can effectively promote the growth of penis in children with concealed penis, reduce the degree of prepuce edema, reduce the incidence of postoperative complications, and improve the quality of life and overall satisfaction. 2022 Vol. 29 (24): 54-56 [Abstract] ( 25 ) HTML (1 KB)  PDF (495 KB)  ( 30 ) 57 Safety and effectiveness of autologous costal cartilage transplantation to construct nasal tip cartilage complex in nasal plastic surgery YAN Chuantao，YANG Hongbo Objective To discuss the safety and effectiveness analysis of autologous costal cartilage transplantation to construct nasal tip cartilage complex in nasal plastic surgery. Methods A total of 148 patients who underwent rhinoplasty in Suizhou High Tech Industrial Park Hospital from June 2019 to June 2021 were selected as the research objects, and divided into the control group (treated with expanded polytetrafluoroethylene) with 74 cases and the study group (treated with autologous costal cartilage transplantation to construct nasal tip cartilage complex) with 74 cases according to random number table method. The measured values of nasal aesthetic angle (nasal lip angle, nasal face angle, frontal nasal angle and nasal dorsal height) and patient satisfaction (nasal shape, nasal height and overall satisfaction) before and after rhinoplasty and postoperative complications of two groups were compared. Results The nasal labial angle, nasal facial angle and frontal nasal angle of the study group after rhinoplasty were higher than the control group, the differences were statistically significant (P ＜0.05). There was no significant difference between the two groups in the nasal dorsal height after rhinoplasty (P＞0.05). After rhinoplasty, the scores of nasal shape, nasal heightand overall satisfaction of the study group were higher than the control group, the differences were statistically significant (P＜0.05). The total incidence of postoperative complications of the study group was lower than the control group,the difference was statistically significant (P＜0.05). Conclusion For patients undergoing rhinoplasty, the surgical treatment of constructing nasal tip cartilage complex with autologous costal cartilage transplantation can effectively improve the nasal morphology. After rhinoplasty, the patients are satisfied with high satisfaction and less complications, which is worthy of reference. 2022 Vol. 29 (24): 57-60 [Abstract] ( 26 ) HTML (1 KB)  PDF (489 KB)  ( 24 ) 61 Application effect of double endoscopic combined choledocholithotomy in elderly patients with common bile duct and gallbladder stones with history of abdominal surgery GE Hailong，WANG Yu，YU Weixin Objective To investigate the application effect of double endoscopic (laparoscopy + choledochoscopy) combined choledocholithotomy in elderly patients with common bile duct and gallbladder stones with history of abdominal surgery. Methods A total of 100 elderly patients with common bile duct and gallbladder stones with history of abdominal surgery admitted to Jintan Hospital Affiliated to Jiangsu University from January 2017 to January 2020 were selected as the research objects, and divided into experimental group (50 cases) and control group (50 cases) by random number table method. The experimental group was treated with double endoscopic (laparoscopy + choledochoscopy) combined choledocholithotomy, and the control group was treated with open cholecystectomy + choledocholithotomy. The operation duration, intraoperative blood loss, postoperative hospitalization time, total postoperative complication rate,hospitalization economic cost and other related indicators were compared between the two groups. Results There were no significant differences in operation duration and total incidence of postoperative complications between the two groups (P>0.05). The postoperative hospital time, overall hospital stay and postoperative feeding time of the experimental group were shorter than those of the control group, the intraoperative blood loss was less than that of the control group, and the hospitalization cost was lower than that of the control group, and the differences were statistically significant (P<0.05). Conclusion For elderly patients with common bile duct complicated with cholecystolithiasis with history of abdominal surgery, double endoscopic (laparoscopy + choledochoscopy) combined with choledocholithotomy can effectively shorten the hospitalization time of patients, reduce the economic cost of patients, and is safe and worthy of clinical promotion. 2022 Vol. 29 (24): 61-64 [Abstract] ( 25 ) HTML (1 KB)  PDF (488 KB)  ( 19 ) 65 Clinical effect of heat-sensitive moxibustion combined with acupoint application in the treatment of anorexia of Spleen and Stomach Qi Deficiency type in children LI Xia，SHAO Mengjie，CONG Fangfang，JU Xiaoqing，ZHU Jilian Objective To observe the clinical effect of heat-sensitive moxibustion combined with Acupoint application in the treatment of anorexia of Spleen and Stomach Qi Deficiency in children. Methods A total of 60 cases Children with anorexia of Spleen and Stomach Qi Deficiency type treated in the Pediatric Clinic and Inpatient of Weihai Hospital of Traditional Chinese Medicine from August 2019 to January 2021 were selected as the research objects. They were randomly divided into the treatment group (30 cases) and the control group (30 cases) according to the random number table method. The treatment group was treated with heat-sensitive moxibustion combined with acupoint application,while the control group was treated with acupoint application. Both groups were treated for 4 weeks. The therapeutic effects, the improvement of main and secondary symptoms of traditional Chinese medicine of the two groups were compared, and the total score of traditional Chinese medicine syndrome, the levels of hemoglobin and Zinc before and after treatment were recorded. Results After treatment, the total effective rate of the treatment group was higher than that of the control group, and the difference was statistically significant (P＜0.05). The effective rate of of poor appetite and reduced appetite in the main symptoms of the treatment group were higher than that of the control group, and, the effective rate of the treatment of sallow complexion, irregular stool, mental fatigue and sweating among the secondary symptoms of the treatment group were higher than that of the control group, and the differences were statistically significant(P＜0.05). The levels of hemoglobin and Zinc in the treatment group were significantly higher than those in the control group, and the differences were statistically significant (P＜0.05). Conclusion Heat-sensitive moxibustion combined with acupoint application can significantly improve the symptoms and signs of anorexia of spleen stomach qi deficiency type in children, enhance appetite and immunity. It has definite clinical curative effect and has a wide application prospect. 2022 Vol. 29 (24): 65-68 [Abstract] ( 22 ) HTML (1 KB)  PDF (592 KB)  ( 31 ) 69 Application of menopausal hormone therapy combined with Dingkundan in perimenopausal syndrome LI Lijun，CHEN Xuemei，LUO Suqin，LIU Wei，XIONG Jieqi，XIE Xiaohua，YANG Huimin Objective To investigate the application effect of Estradiol/Estradiol-Dydrogesterone Tablets combined with Dingkundan in perimenopausal syndrome. Methods A total of 30 patients with perimenopausal syndrome who were admitted to Jiangxi Maternal and Child Health Hospital from January to December 2020 were selected as the research objects, and they were divided into the control group and the observation group by random number table method, 15 cases in each group. The control group received Estradiol/Estradiol-Dydrogesterone Tablet treatment, and the observation group received Dingkundan treatment on the basis of the control group. The degree of symptom improvement, coagulation function, quality of life and the incidence of adverse reactions were compared between the two groups. Results There were no significant differences in the scores of modified Kupperman menopausal index (KMI), coagulation function index and the scores of quality of life index between the two groups before treatment(P>0.05).The KMI score of patients in the observation group after treatment was lower than that of the control group, and the difference was statistically significant (P<0.05).After treatment,the levels of prothrombin time(PT)and partial prothrombin time(APTT)of the observation group were shorter than those of the control group, the levels of original (FIB) and D-Ⅱpolymer (D-Ⅱ) of the observation group were lower than those of the control group, and the level of antithrombin Ⅲ (AT-Ⅲ) of the observation group was higher than that of the control group, and the differences were statistically significant (P<0.05). There was no significant difference in thrombin time (TT) after treatment between the two groups (P>0.05). After treatment, the quality of life score of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The incidence of breast tenderness in the observation group was 26.67%, which was lower than that in the control group (86.67%), and the difference was statistically significant (P<0.05). Conclusion Patients with perimenopausal syndrome receiving Estradiol/Estradiol-Dydrogesterone Tablets combined with Dingkundan therapy can better improve symptoms, reduce the adverse effects on coagulation function, and improve the quality of life of patients. 2022 Vol. 29 (24): 69-72 [Abstract] ( 27 ) HTML (1 KB)  PDF (593 KB)  ( 17 ) 73 Second stage of labor uses the lateral position of force in epidural labor analgesia KE Ying，HUANG Renying，XIAO Wenping Objective To analyze the value of lateral force in the second stage of labor. Methods A total of 60 births from the Department of Obstetrics, Ganzhou Maternal and Child Health Hospital from December 2019 to December 2020 were selected as the research subjects, and they were divided into observation group (30 cases) and control group(30 cases) using the digital table method. Patients in the control group used the second stage, and the observation group used the lateral supine force in the second stage. Natural delivery rates, delivery indicators and analgesic satisfaction were compared between the two groups. Results The natural delivery rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The second stage of labor in the observation group was shorter than that in the control group, and the difference was statistically significant (P<0.05). The exertion time of the observation group was shorter than that of the control group, and the difference was statistically significant (P<0.05). The postpartum blood loss of the observation group was less than that of the control group, and the difference was statistically significant (P<0.05). The analgesic satisfaction of the observation group was higher than that of the control group after intervention, and the difference was statistically significant (P<0.05). Conclusion Epidural labor analgesia has high clinical value in the second stage of labor and lateral force. It can improve the speed of labor and improve satisfaction. 2022 Vol. 29 (24): 73-75-79 [Abstract] ( 24 ) HTML (1 KB)  PDF (572 KB)  ( 42 ) 76 Changes and significance of thrombelastogram in intrahepatic cholestasis of pregnancy LIANG Lili，YIN Xu′ai Objective To investigate the changes and significance of thrombelastogram (TEG) in intrahepatic cholestasis of pregnancy (ICP). Methods A total of 87 cases of ICP diagnosed in the Department of Obstetrics and Gynecology of Chaohu Hospital Affiliated to Anhui Medical University from January 2018 to August 2020 were retrospectively collected as the ICP group, and further divided into the mild ICP group and the severe ICP group. Another 100 healthy pregnant women during the same period were collected as the healthy control group, and the TEG indicators among the groups were compared. Results The reaction time (R) and maximum amplitude (MA) of TEG indexes in ICP group were higher than those in control group, the differences were statistical significance (P＜0.05), but there were no statistical significances in other TEG indexes between the two groups (P＞0.05). The R of TEG indexes in severe ICP group was higher than that in mild ICP group, and the difference was statistically significant (P＜0.05), but there were no significant differences in other TEG indexes between the two groups (P＞0.05). The R and MA of TEG indexes in severe ICP group were higher than those in control group, and the differences were statistically significant (P＜0.05), but there were no significant differences in other TEG indexes between the two groups (P＞0.05). There were no significant differences in TEG indexes between mild ICP group and control group (P＞0.05). Conclusion TEG index can fully reflect the changes of coagulation status of ICP patients and reflect the severity of their disease to a certain extent, thus providing an important basis for the evaluation and treatment of the disease. 2022 Vol. 29 (24): 76-79 [Abstract] ( 27 ) HTML (1 KB)  PDF (564 KB)  ( 18 ) 80 Therapeutic effect and safety of ligation of the descending branch of uterine artery on postpartum hemorrhage caused by uterine asthenia FU Ye Objective To analyze the value of ligation of descending branch of uterine artery in patients with postpartum hemorrhage caused by uterine atony. Methods A total of 80 patients with postpartum hemorrhage caused by uterine atony admitted to the Department of Obstetrics and Gynecology of Hainan Western Central Hospital from January 2020 to August 2021 were selected as the research objects, and they were divided into the control group and the observation group by random number table method, with 40 cases in each group. The control group was treated with misoprostol, and the observation group was treated with ligation of the descending branch of the uterine artery on the basis of the control group. The total effective rate, total incidence of adverse reactions and clinical indicators were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P＜0.05). The total incidence of adverse reactions in the observation group was lower than that of the control group, and the difference was statistically significant (P＜0.05). The blood loss of observation group was less than those of control group 2 and 24 h after delivery, and 6-keto-PGF1α were lower than those in the control group and the corrected hemoglobin value PGE2 and PGF2α were higher than those in the control group and the differences were statistically significant (P＜0.05). Conclusion The application of ligation of descending branch of uterine artery in the treatment of postpartum hemorrhage caused by uterine atony can improve the therapeutic effect and safety，and also reduce the overall blood loss，which is worthy of clinical application. 2022 Vol. 29 (24): 80-83 [Abstract] ( 30 ) HTML (1 KB)  PDF (557 KB)  ( 24 ) 84 Clinical effect on treating lumbar disc herniation with deficiency of liver and kidney by clicking on the Du meridian method combined with Bushen Zhuangjin Decoction based on "Tong Du Qiang Ji" theory WANG Weijia，LI Changning， WU Tianlin，ZHANG Luandi，LIN Qiaoxuan,ZHOU Tengxiang Objectives To explore the therapeutic effect and guiding significance of the theory of "Tong Du Qiang Ji"on lumbar disc herniation (LDH) with deficiency of liver and kidney by clicking on the Du meridian method combined with Bushen Zhuangjin Decoction, and to provide ideas for clinical work. Methods Sixty patients with lumbar disc herniation with liver and kidney deficiency admitted to the Third People′s Hospital Affiliated to Fujian University of Traditional Chinese Medicine from January to December 2021 were selected as the research subjects, and they were divided into experimental group and control group according to random number table method, with 30 cases in each group.The experimental group was treated by clicking on the Du meridian method combined with Bushen Zhuangjin Decoction, and the control group was treated with oral Bushen Zhuangjin Decoction. The pain rating index (PRI), visual analogue scale (VAS), lumbar range of motion, straight leg elevation angle before and after treatment and the treatment effect were compared between the two groups. Results There were no significant differences in PRI score, VAS score,lumbar range of motion and straight leg elevation angle between the two groups before treatment (P>0.05). The PRI score and VAS score of the two groups after treatment were lower than those before treatment, the lumbar range of motion and straight leg elevation angle were higher than those before treatment, and the differences were statistically significant (P<0.05). After treatment, the PRI score and VAS score of the experimental group were lower than those of the control group, the lumbar range of motion and straight leg elevation angle of the experimental group were higher than those of the control group, and the differences were statistically significant (P<0.05). The total effective rate of the experimental group after treatment was 83.3%, which was higher than 56.7% of the control group, and the difference was statistically significant (P<0.05). Conclusion Under the guidance of the theory of "Tong Du Qiang Ji", the click on the Du meridian method combined with Bushen Zhuangjin Decoction for the treatment of LDH can significantly relieve the symptoms and pain of patients with waist and leg pain, promote the recovery of waist function, and improve the quality of life and work of patients, which shows the important guiding significance for clinical work. 2022 Vol. 29 (24): 84-87-91 [Abstract] ( 20 ) HTML (1 KB)  PDF (549 KB)  ( 26 ) 88 The guidance of Treatise on Epidemic Febrile Disease in the treatment of sepsis HUANG Tianhua,ZHOU Xianshi,XIA Qing Treatise on Epidemic Febrile Disease is a classic masterpiece of Doctrine of Epidemic Febrile Disease, and its concepts still guide the clinical practice of treating warm diseases. Sepsis is one of the common acute and critical diseases in clinical practice, with high morbidity and mortality and poor prognosis. The onset and evolution of sepsis are similar to febrile disease. Some provisions of Treatise on Epidemic Febrile Disease fit well with the core current treatment concepts of sepsis, which can be reflected in 6 aspects including protecting the lung, clearing heat and defensing against the evil superficially, cutting off and reversing the evolving of the disease, excreting the heat and preserving body fluid, tonifying and dredging the stomach, diffusing Yang qi and urinating the dampness, intervening urgently to prevent the complications. Learn from the past and seek the new. To conclude, Treatise on Epidemic Febrile Disease has an important guidance for the treatment of sepsis, and strengthen the learning of some provisions of Treatise on Epidemic Febrile Disease can help to understand and treat sepsis. 2022 Vol. 29 (24): 88-91 [Abstract] ( 22 ) HTML (1 KB)  PDF (509 KB)  ( 63 ) 92 Clinical application value of combined detection of D-dimer, NLR and BNP in the diagnosis and treatment of acute exacerbation of chronic obstructive pulmonary diseas XIAO Shibin,ZHANG Yufang,HUANG Changyan Objective To investigate the clinical application value of the combined detection of D-dimer (D-D),neutrophilto lymphocyte ratio (NLR) and B-type natriuretic peptide (BNP) in the diagnosis and treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods A total of 160 patients with chronic obstructive pulmonary disease (COPD) in Ganzhou Municipal Hospital from January 2021 to December 2021 were selected as the research objects. According to the conditions, the patients in the acute exacerbation stage were set as the observation group, and the patients in the stable stage were set as the control group. The levels of D-D, NLR and BNP in the two groups were detected and compared, and the Pearson correlation was used to analyze the correlation among D-D, NLR and BNP, and the receiver operating characteristic curve (ROC) was used to analyze the diagnosis of AECOPD by D-D, NLR and BNP value. Results The levels of BNP in the observation group were lower than those in the control group, and the levels of D-D and NLR were higher than those in the control group, the differences were statistically significant (P<0.05). The correlation analysis showed that D-D, NLR and BNP were all negatively correlated(r=-0.803, -0.862, P<0.001). The ROC analysis results showed that the cut-off values of D-D, NLR, BNP and the combined diagnosis of liver cirrhosis were 1.525, 5.740, 200.075 and 0.485 respectively, and the areas under the curve were 0.974, 0.993, 1.000 and 1.000 respectively. The combined diagnosis was higher than the single diagnosis.Conclusion The combined detection of D-D, NLR and BNP has high sensitivity and specificity in the diagnosis and treatment of AECOPD, and has high diagnostic value, which is worthy of clinical promotion. 2022 Vol. 29 (24): 92-94-98 [Abstract] ( 23 ) HTML (1 KB)  PDF (461 KB)  ( 30 ) 95 Diagnostic value of combined detection of serum ferritin, glutamyl transpeptidase, adenosine deaminase and 5′-nucleotidase in liver cancer QIAO Li，LI Ming Objective To study the diagnostic value of serum ferritin (SF), glutamyltranspeptidase (GGT), adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) in the diagnosis of liver cancer. Methods A total of 200 patients with liver cancer treated in Xinjiang Medical University Affiliated Hospital of Traditional Chinese Medicine from April 2020 to March 2022 were selected as the liver cancer group, and 195 patients with benign liver tumors during the same period were selected as the benign group. The levels of SF, GGT, ADA and 5′-NT were measured and compared between the two groups. The pathological diagnosis results were used as the gold standard to calculate the consistency, sensitivity, specificity and accuracy of SF, GGT, ADA and 5′-NT in single and combined diagnosis of liver cancer. Results The levels of SF, GGT, ADA and 5′-NT in liver cancer group were higher than those in benign group, and the differences were statistically significant (P<0.05). Taking pathological diagnosis results as the gold standard, the consistency between SF+GGT+ADA+5′-NT and pathological results was better than that of SF, GGT, ADA and 5′-NT. The sensitivity and accuracy of SF+GGT+ADA+5′-NT combined diagnosis were higher than those of SF, GGT, ADA and 5′-NT alone,the differences were statistically significant (P<0.005). There was no statistically significant difference in the specificity of SF, GGT, ADA and 5′-NT in the diagnosis of hepatocellular carcinoma (P>0.005). There were no statistically significant differences in the sensitivity, specificity and accuracy of SF, GGT, ADA and 5′-NT (P>0.005). Conclusion The serum levels of SF, GGT, ADA and 5′-NT in patients with liver cancer are increased, and the combined detection of SF, GGT, ADA and 5′-NT can improve the diagnostic sensitivity of liver cancer, and the diagnostic efficiency is high. 2022 Vol. 29 (24): 95-98 [Abstract] ( 21 ) HTML (1 KB)  PDF (458 KB)  ( 22 ) 99 Analysis of social support and self-disclosure in patients with benign prostatic hyperplasia after transurethral resection of the prostate SHU Chang，ZONG Haiyan，ZHAO Jiqing Objective To investigate the conrrelation between perceived social support, self-disclosure and sexual function in patients with benign prostatic hyperplasia after transurethral resection of the prostate. Methods A total of 88 patients with benign prostatic hyperplasia and underwent transurethral resection of the prostate in the Department of Urology of the First People′s Hospital of Jiujiang City from September 2020 to February 2022 were prospectively selected. According to the postoperative international index of erectile function (IIEF) of the patients, the patients were divided into mild group (46 cases) and severe group (42 cases). General clinical data, perceived social support scale(PSSS), Berkeley expressivity questionnaire (BEQ), residual urine volume after emptation and the other conditions of the patients were collected, univariate and multivariate logistic were used to analyze the related factors affecting the postoperative sexual function of the patients. Results Univariate analysis showed that there were statistically significant differences in marital status, smoking history, drinking history, PSSS, BEQ and residual urine volume after emptation between the mild-moderate group and the severe group (P<0.05). Multivariate logistic results indicated that marital status (β=2.432, OR=11.382, 95%CI=1.641-78.924) and residual urine volume (β=0.044, OR=1.045, 95%CI=1.003-1.089) were risk factors for sexual function after transurethral resection of prostate, PSSS (β=-0.163, OR=0.850, 95%CI=0.752-0.959) and BEQ (β=-0.359, OR=0.698, 95%CI=0.528-0.924) were protective factors for sexual function after transurethral resection of prostate (P<0.05). Conclusion No spouse and high residual urine volume are independent risk factors affecting sexual function of patients, while high PSSS and high BEQ are independent protective factors affecting sexual function of patients. In clinical nursing, relative measures should be taken according to the corresponding situation of patients to adjust the physical and mental conditions of patients. 2022 Vol. 29 (24): 99-102 [Abstract] ( 23 ) HTML (1 KB)  PDF (462 KB)  ( 36 ) 103 Suicidal risk and related influencing factors of long-term peritoneal dialysis patients DU Lyulyu，WANG Lei，MAO Yanling，YU Jie，LI Ying，GU Mingying Objective To explore the suicidal risk and influencing factors of long-term peritoneal dialysis patients.Methods The clinical data of 98 peritoneal dialysis patients with end-stage renal disease treated in the Department of Nephrology, Jiading District Central Hospital Affiliated to Shanghai University of Medicine & Health Science from January 2018 to January 2020 were retrospectively analyzed. The Chinese version of Pittsburgh sleep quality index (PSQI)and concise Mini-International Neuropsychiatric Interview (M.I.N.I.) were used for questionnaire survey and relevant scores were calculated. According to the results of the questionnaire, they were divided into high risk group (34 cases)and low risk group (64 cases). The related indexes of the two groups were compared. Multivariate logistic regression and Cox regression were used to analyze the influencing factors of suicide risk in patients with peritoneal dialysis. Results Univariate analysis showed that there were significant differences in dialysis time peritoneal dialysis fluid retention overnight rate, sleep efficacy score and sleep disorder score between the two groups (P<0.05).Multivariate logistic regression showed that dialysis duration (OR=1.019, 95%CI=1.002-1.036, P=0.033) and sleep efficacy (OR=2.498, 95%CI=1.194-5.228, P=0.015) were independent risk factors for high suicidal tendency after adjusting for related factors.COX regression revealed that the cumulative risk of suicide would increase as dialysis duration gets longer and sleep efficacy scores get higher (P=0.035). Conclusion The risk of suicide is comparatively high in patients with peritoneal dialysis. Patients with higher scores in sleep efficacy and longer dialysis duration are more likely to commit suicide. 2022 Vol. 29 (24): 103-106 [Abstract] ( 29 ) HTML (1 KB)  PDF (497 KB)  ( 45 ) 107 Current status and influencing factors of pelvic floor muscle training in women with stress urinary incontinence KONG Junmei，XIE Junfang，WU Hengshuang，HOU Ying，LI Sumei，ZHANG Fengzhi▲ Objective To analyze the current situation and influencing factors of pelvic floor muscle training for female stress urinary incontinence. Methods A total of 94 patients with stress urinary incontinence who were treated in the Department of Gynecology, the Third Affiliated Hospital of Zhengzhou University from October 2019 to October 2020 were selected as the research objects. The implementation status of pelvic floor muscle training was investigated by questionnaire. According to the results, the patients were divided into the implementation group and the non-implementation group, and the influencing factors were analyzed. Results Among 94 patients with stress urinary incontinence, 41 patients (43.62%) performed pelvic floor muscle training, 53 cases (56.38%) did not perform pelvic floor muscle training. Univariate analysis showed that age, highest level of education, mode of delivery, weight gain, and current presence or absence of urinary incontinence were associated with the status of pelvic floor muscle training (P<0.05). Multivariate logistic regression analysis showed that weight gain (P=0.013, OR=2.855, 95%CI: 1.244-6.554) and urinary incontinence (P=0.001, OR=3.710, 95%CI: 1.718-8.013) were independent influencing factors of pelvic floor muscle training implementation. Conclusion The pelvic floor muscle training of patients with stress urinary incontinence is not well performed, and weight gain and the presence of urinary incontinence are independent influencing factors. Effective nursing interventions should be actively implemented to improve the implementation rate of pelvic floor muscle training in patients with stress urinary incontinence. 2022 Vol. 29 (24): 107-110 [Abstract] ( 22 ) HTML (1 KB)  PDF (492 KB)  ( 20 ) 111 Effect of quality control circle and delicacy management on the intestinal cleanliness of the patients with colonic polyps QU Wenjuan，PEI Shuting，DENG Yanhong Objective To investigate the effectiveness of quality control circle (QCC) and Delicacy management (DM)on the intestinal cleanliness of the patients with colonic polyps. Methods Eighty patients with colonic polyps hospitalized in the Jiujiang No. 1 People′s Hospital from January to July 2021 and underwent routine electric colonoscopy were enrolled. The patients were assigned as the control group (n=40) and the observation group (n=40) using the random number table. The control group patients took the medicine conventionally to cleanse their intestinal canal after the guide of the doctor in charge and the primary nurse. Whereas the observation group patients were intervened with QCC and DM in order to analyze the intestinal cleanliness and the incidence of adverse events of the two groups. Results The intestinal cleanliness rate of observation group was higher than that of control group, and the difference was statistically significant (P<0.05). The occurrence rates of anxiety, abdominal distention, nausea and vomiting, debilitation of the observation group were lower that of control group, and the differences were statistically significant (P<0.05). Conclusion The combination of QCC and DM can effectively improve intestinal cleanliness of the patients with colonic polyps, enlarge the doctor′s field of vision operating microscopic examination, save time on endoscope operation and reduce the adverse events of bowel preparation, therefore alleviating patients′ pain and improve their satisfaction. 2022 Vol. 29 (24): 111-113 [Abstract] ( 19 ) HTML (1 KB)  PDF (556 KB)  ( 26 ) 114 Discussion and optimization of drug management model for clinical trials JIANG Yun，HENG Jianfu The management of experimental drugs is crucial in the management of drug clinical trials. The quality of management directly affects the clinical trials and the safety of subjects who use the drug. To protect the safety of subjects, safeguard the rights and interests of the subjects, ensure reliable quality, controllabe process and accurate data of drug clinical trails, standardize all aspects of drug management for clinical trials, such as receiving, storage, distribution, use, recovery and return, and explore the management mode of drug for clinical trials, construction and management of clinical trial pharmacies with a view to optimizing, the advantages and disadvantages of the current management mode in China were analyzed, and the management mode of experimental drugs in Hu′nan Cancer Hospital was taken as an example to introduce how to further optimize the management mode of experimental drugs, and provide reference for standardized drug management for clinical trials. 2022 Vol. 29 (24): 114-116-120 [Abstract] ( 23 ) HTML (1 KB)  PDF (605 KB)  ( 79 ) 121 Application effect of fine management in hospital management WANG Zhongyi，ZHAO Xue Objective To study the application value of fine management in hospital management. Methods The clinical data of 100 hospitalized patients in Hongqi Hospital Affiliated to Mudanjiang Medical College from March to December 2019 were retrospectively selected as the control group, and the clinical data of 100 hospitalized patients from January to June 2020 were selected as the observation group. Patients in the control group received routine management, while patients in the observation group received fine management. The total satisfaction of medical services, the total incidence of adverse events and work errors were compared between the two groups. Results The total satisfaction of medical service in the observation group was 96.00%, which was higher than 80.00% in the control group, and the difference was statistically significant(P<0.05).The total incidence of adverse events in the observation group was 4.00%,lower than 10.00% in the control group, and the difference was statistically significant (P<0.05). The scores of management problems, mistakes and improper operation in the observation group were lower than those in the control group,and the differences were statistically significant (P<0.05). Conclusion The application of fine management measures in hospital management has achieved remarkable results and can significantly improve the satisfaction of medical services. 2022 Vol. 29 (24): 121-123 [Abstract] ( 26 ) HTML (1 KB)  PDF (552 KB)  ( 18 ) 124 Implementation of quality control in medical record management ZHANG Jiandong Objective To explore and analyze the implementation effect of quality control in medical record management. Methods Zhaoqing First People′s Hospital began to implement quality control in medical record management since January 2020. A total of 1150 medical records of each clinical department before the implementation of quality control from January to December 2019 were selected as the reference group, and 1100 medical records of each clinical department after the implementation of quality control from January to December 2020 were selected as the study group. The quality grade distribution of medical records and the occurrence of defects in medical records were compared between the two groups. Results The proportions of class A, class B and class C medical records in the study group were 92.45%, 6.27% and 1.27% respectively. The proportions of class A, class B and class C medical records in the reference group were 84.87%, 9.74% and 5.39% respectively. The quality of medical records in the study group was better than that in the reference group, and the difference was statistically significant (P<0.05). The incidence of defects in the medical records of the study group was 2.00% (22/1100), which was lower than 6.78% (78/1150) of the reference group, and the difference was statistically significant (P<0.05). Conclusion The implementation of quality control in the management of medical records can effectively reduce the incidence of defects in medical records, help to improve the quality level of medical records, and improve the overall quality of medical record management. 2022 Vol. 29 (24): 124-126 [Abstract] ( 19 ) HTML (1 KB)  PDF (553 KB)  ( 38 ) 127 Application effect of intelligent dispensing mode in the inpatient pharmacy SUN Dan，GUO Haifei Objective To explore the application effect of intelligent dispensing mode in the inpatient pharmacy. Methods Information related to drug dispensing in the Inpatient Pharmacy of Peking University Sixth Hospital from July to December 2020 was selected as the study population, and drug dispensing under the traditional dispensing mode from July to September 2020 was selected as the control group (n=67 864), drug dispensing under the intelligent dispensing mode from October to December 2020 was selected as the study group (n=74 308), 50 inpatients were included in each group for satisfaction survey. The total incidence of error events, single-dose dispensing time and patient satisfaction were compared between the two groups. Results The total incidence of error events in the study group was lower than that in the control group, the single-dose transfer time in the study group was lower than that in the control group, and patient satisfaction in the study group was higher than that in the control group, with statistically significant differences(P＜0.05). Conclusion The application of intelligent dispensing mode in inpatient pharmacy is effective and can effectively improve the quality of drug dispensing, work efficiency and patient satisfaction. It is in line with the development trend of pharmacy informatization and automation. 2022 Vol. 29 (24): 127-129-133 [Abstract] ( 24 ) HTML (1 KB)  PDF (576 KB)  ( 32 ) 130 Application effect of continuous quality improvement mode based on continuous find organize clarify understand select plan do check act method in improving children′s physical examination triage DENG Tingyue Objective To explore the application effects of continuous quality improvement model based on continuous find organize clarify understand Find-Organize-Clarify-Understand-Select-Plan-Do-Check-Action (FOCUS-PDCA) in the children′s physical examination triage. Methods A total of 1000 children checked from February 2020 to February 2021 in Jiangmen Maternity and Child Health Hospital were selected as research subjects. According to random number table, they were divided into study group and control group, with 500 cases in each group. The study group took FOCUS-PDCA-dominated continuous quality improvement modes, the control group took the routine modes. The clincial satisfaction, waiting time for physical examination time, health knowledge awareness rate were compared between two groups. Results The clinical satisfaction in the study group was higher than control group, with statistically significant difference (P＜0.05). The health knowledge awareness rate in the study group was higher than control group, with statistically significant difference (P＜0.05). The physical examination time and awaiting time in the study group were shorter than control group, with statistically significant difference (P＜0.05). Conclusion FOCUS-PDCA-dominated continuous quality improvement mode can improve the children′s health knowledge mastery degrees, shorten the physical examination time and increase the clinical satisfaction. It is worthy of application and promotion. 2022 Vol. 29 (24): 130-133 [Abstract] ( 27 ) HTML (1 KB)  PDF (564 KB)  ( 53 ) 134 Effect of mixed pharmacology teaching mode based on "flipped classroom"under the background of "internet+" FU Hui，ZHOU Le，XIA Haishan，QIN Dongyun，XU Daohua Objective To explore the new online and offline mixed teaching mode based on "flipped classroom", comprehensively evaluate the application value of this teaching mode in pharmacology teaching, and provide reference for further promoting the pharmacology teaching reform suitable for universities in the future. Methods A total of 130 students from two classes of clinical medicine major of grade 2018, Guangdong Medical University from March to July 2020 were selected as the research objects and divided into experimental group (n=64) and control group (n=66) by class grouping. The experimental group was taught by the new mode of online and offline integrated flipped classroom,while the control group was taught by traditional teaching mode. The evaluation of teaching effect of two groups was collected and the test score of the two groups were compared. Results The students in the experimental group had higher evaluation of teaching effect than control group, the difference was statistically significant (P<0.05). The average score of offline tests in the experimental group was higher than that of the control group, and the differences were statistically significant (P<0.05). However, there was no significant difference in the average score of online tests between the two groups (P>0.05). Conclusion The new teaching mode can improve the teaching effect, and is helpful to the cultivation of learning interest, knowledge mastery and ability. It is worthy of being widely applied and promoted in pharmacology teaching. 2022 Vol. 29 (24): 134-137 [Abstract] ( 26 ) HTML (1 KB)  PDF (726 KB)  ( 162 ) 138 Application effect of OEC management method in the practice teaching of basic nursing WU Yuanrong，ZENG Senmei，HUANG Min，CAI Xinjian，LUO Lina，CHEN Huali Objective To explore the application effect of OEC management method in the practice teaching of basic nursing. Methods A total of 350 nursing students of grade 2019 and Grade 2020 in Guangzhou Nanfang College were selected as the research objects by convenient sampling. According to different grades, they were divided into experimental group (grade 2020, 172 students) and control group (grade 2019, 178 students). The students of experimental group adopted OEC management method for practical training teaching management, while the students of control group adopted traditional management method for practical training teaching management. The final practical training score,practical training base management effect, and practical training course satisfaction of the two groups were compared after the experiment. Results The Practical training and assessment scores, practical training base management effect and practical training course satisfaction of the experimental group were higher than those of the control group, and the differences were statistically significant (P<0.05). Conclusion OEC management mode can effectively improve the skill operation level, self-management ability and satisfaction of nursing students, promoting the improvement of practical teaching quality of basic nursing. 2022 Vol. 29 (24): 138-141 [Abstract] ( 17 ) HTML (1 KB)  PDF (730 KB)  ( 43 ) 142 Application of high-fidelity laparoscopic simulation teaching and training system in general surgery clinical teaching 梁博 刘鹏 黄艳 郑彪 孙培伟 巩鹏 Objective To explore the application value of the high-fidelity laparoscopic simulation teaching and training system in the clinical teaching of general surgery. Methods A total of 60 undergraduates who practiced in the Department of General Surgery of Shenzhen University General Hospital from October 2020 to October 2021 were selected as the research objects and divided into the control group and the study group by random number table method, with 30 students in each group. The interns in the control group received conventional teaching and training mode, while the interns in the study group received high simulation laparoscopic simulation teaching and training system. The scores of assessment, teaching satisfaction, learning interest and learning autonomy were compared between the two groups. Results After training, the scores of cutting, nail transfer and hand movements in the study group were higher than those in the control group, and the time of knot tying and connecting suture were shorter than those in the control group, and the differences were statistically significant (P<0.05). The teaching satisfaction of the study group was higher than that of the control group, and the difference was statistically significant (P<0.05). There were no significant differences in the scores of learning interest and learning autonomy between the two groups before training (P>0.05). The scores of learning interest and learning autonomy in the study group after training were higher than those in the control group,and the differences were statistically significant (P<0.05). Conclusion For general surgery undergraduate interns,adopting a high-fidelity laparoscopic simulation teaching and training system can promote the improvement of interns′professional skills, strengthen interns′ learning enthusiasm and initiative, and improve interns′ satisfaction with teaching methods, which has certain value. 2022 Vol. 29 (24): 142-144-149 [Abstract] ( 18 ) HTML (1 KB)  PDF (687 KB)  ( 16 ) 145 Innovation and exploration of pharmaceutical English teaching by integrating the English version of Chinese Pharmacopoeia with the textbook content in traditional Chinese medicine universities LIU Yue，KANG Rong，ZHAO Jianfeng，ZHANG Lanzhen Pharmaceutical English is a new pharmacy course which set up in the universities of traditional Chinese medicine in recent years. Due to the wide content of its corresponding subjects as well as the lack of standardized teaching material, the majority teaching work of pharmaceutical English is still in a spontaneous and disorderly state. In the course of lesson preparation and delivering, the scientific curriculum design and reasonable arrangement of content are the biggest challenges to the teaching of pharmaceutical English. Under the guidance of traditional Chinese medicine theory, our course group tries to integrate the English version of Chinese Pharmacopoeia into the pharmaceutical English teaching for the first time, and the featured contents of preface, Chinese crud drugs, oil, fats and extractives as well as traditional Chinese patent medicines were explained in detail, respectively. The results indicated that the newly content could fully reflect the cultural characteristics of traditional Chinese medicine as well as cover the knowledge system of the science of Chinese materia medica, and also owned the features of strong professionalism, authority and innovation. Our study aiming to provide the scientific basis and theoretical reference for the better development of pharmaceutical English teaching in the field of traditional Chinese medicine. 2022 Vol. 29 (24): 145-149 [Abstract] ( 17 ) HTML (1 KB)  PDF (734 KB)  ( 114 ) 150 Construction and thinking of ideological and political courses in obstetrics and gynecology nursing WANG Qianqian，XIE Xiaofang，GAO Yiyuan Moral cultivation is the fundamental task of college education, and curriculum ideological and political education is an important measure to achieve moral cultivation, through the ideological and political construction of courses can realize the educational function of professional courses. Obstetrics and gynecology nursing is the core curriculum of the nursing major. The teachers of the curriculum team work together to excavate ideological and political materials, in order to form a complete curriculum ideological and political teaching resource system. This article firstly expounds the necessity of ideological and political development of nursing courses in obstetrics and gynecology. Comprehensive quality and clinical nursing quality are directly related to maternal and infant health. Secondly, the ideological and political construction of the obstetrics and gynecology nursing courses is introduced from four aspects: the ideological and political education model, the ideological and political theme, the integration plan of ideological and political materials and the implementation effect. Finally, according to the ideological and political construction of the obstetrics and gynecology nursing courses, the prerequisites for better ideological and political education for this course are put forward:strengthening the ideological and political concepts of the professiona teachers, optimizing the teaching syllabus and teaching plan, and using a variety of teaching methods and means. This research explored the collaborative education and teaching methods of professional courses and ideological and political courses, so as to effectively integrate knowledge transfer and value guidance, help the ideological and political construction of obstetrics and gynecology nursing courses, and promote the all-round development of students. 2022 Vol. 29 (24): 150-153 [Abstract] ( 20 ) HTML (1 KB)  PDF (745 KB)  ( 168 ) 154 Application effect of senior role experience combined with case teaching method in the training of new nurses LI You，KONG Linshu Objective To explore the application effect of elder role experience combined with case teaching method in the training of new nurses. Methods Twenty-nine new nurses recruited in May 2019 in Liaoning Jinqiu Hospital (Liaoning Geriatric Hospital) were selected as the control group, and 30 new nurses recruited in January 2020 were selected as the observation group. The control group adopted the traditional training method, while the observation group adopted the senile role experience combined with case teaching method in addition to the traditional training method. The assessment scores and comprehensive work ability of the two groups were compared, and the evaluation of the observation group on the training mode of role experience combined with case teaching method was investigated. Results The theoretical scores and skills scores of nurses in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The scores of clinical problem solving ability, nursing safety awareness, team cooperation ability, humanistic care and comprehensive service ability of nurses in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). In the evaluation of the senile role experience combined with case teaching method in the observation group, the highest evaluation was given to stimulating the interest of geriatric nursing work, strengthening nursing safety awareness and cultivating the ability to analyze problems, and 93.3% of the new nurses thought it was "very helpful". Conclusion The application of senile role experience combined with case teaching method in the training of new nurses in geriatric hospitals is a beneficial exploration and plays a role in promoting the development of clinical nursing training in geriatric hospitals. 2022 Vol. 29 (24): 154-157-161 [Abstract] ( 18 ) HTML (1 KB)  PDF (786 KB)  ( 53 ) 158 Effect of health education based on knowledge, attitude and practice model on compliance behavior and calcium and phosphorus metabolism in maintenance hemodialysis patients JIANG Liqiong,ZHANG Canzhi,LUO Chang,LI Haiying,LU Juan Objective To explore the effect of knowledge, attitude and practice model (KAP) health education for maintenance hemodialysis (MHD) patients. Methods A total of 100 MHD patients admitted to Changsha Central Hospital from June 2020 to June 2021 were selected as the research object. They were divided into control group and observation group by random number table method, with 50 patients in each group. The control group received routine health education, and the observation group received KAP health education on the basis of the control group. The scores of compliance behavior, self-efficacy, blood phosphorus and blood calcium were compared between the two groups before intervention, 3 months and 6 months after intervention. Results There was no significant difference in compliance behavior and self-efficacy score between the two groups before intervention (P>0.05). The compliance behavior and selfefficacy score of the two groups increased gradually after 3 and 6 months of intervention, and the compliance behavior and self-efficacy score of the observation group were higher than that of the control group, the differences were statistically significant (P<0.05). There was no significant difference in blood calcium and phosphorus levels between the two groups before intervention (P>0.05). After 3 and 6 months of intervention, the blood phosphorus level in both groups gradually decreased, and the blood calcium level gradually increased, the serum phosphorus level of the observation group was lower than that of the control group, and the serum calcium level was higher than that of the control group,the differences were statistically significant (P<0.05). Conclusion Health education based on KAP can improve the calcium and phosphorus metabolism of MHD patients, and improve their compliance behavior and self-efficacy. 2022 Vol. 29 (24): 158-161 [Abstract] ( 18 ) HTML (1 KB)  PDF (676 KB)  ( 29 ) 162 Effect of case teaching method in internal medicine teaching DONG Qi,LIU Wupeng Objective To explore the effect of case teaching method in science teaching. Methods Eighty students from two classes of clinical medicine major in Guizhou Medical University were selected as the research objects, and divided into control group (n=40) and observation group (n=40) by class grouping. The control group used conventional teaching method, and the observation group used case teaching method. The scores of teaching effect evaluation, teaching quality evaluation, degree of knowledge mastery of internal medicine theory and case analysis ability before and after teaching were compared between the two groups, and students′ satisfaction with teaching methods was evaluated by self-made satisfaction scale. Results The scores of communication ability, learning enthusiasm, teamwork, matters for attention and copywriting in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The scores of teacher attitude, teaching ability, communication between teachers and students, content mastery and overall evaluation in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). Before teaching, there were no significant differences in the scores of students′ mastery of internal medicine theoretical knowledge and case analysis ability between the two groups (P>0.05). After teaching, the scores of students′ mastery of internal medicine theoretical knowledge and case analysis ability in the two groups were higher before teaching, and the scores in the observation group were higher than those in the control group, the difference was statistically significant (P<0.05). The observation group were more satisfied with case teaching method than the control group, and the difference was statistically significant (P<0.05). Conclusion The application of case teaching method in internal science teaching can improve teaching quality and teaching effect, improve students′ theoretical knowledge mastery and case analysis ability, and students′ satisfaction with case teaching method is high, which is worth promoting. 2022 Vol. 29 (24): 162-165 [Abstract] ( 19 ) HTML (1 KB)  PDF (675 KB)  ( 20 ) 166 Application effect of position management based on infant position assessment tool combined with developmental supportive nursing on premature infants JIANG Nanyu,LI Xiaoxiao,XIAO Xia Objective To explore the application effect of position management based on infant position assessment tool combined with developmental supportive nursing on premature infants. Methods A total of 60 premature infants treated in Pingxiang People′s Hospital, Jiangxi Province, from January 2021 to February 2022 were selected as the research subjects, and they were divided into the control group (n=30) and the study group (n=30) by the random number table method. The two groups of premature infants were given routine developmental supportive nursing, and the control group was supported by bird′s nest position while the study group adopted infant position assessment tool to guide the placement of bird′s nest position. The nutritional support status, feeding status, growth and development and clinical outcomes were compared between the two groups of premature infants. Results After intervention, the gastric tube indwelling time, total enteral nutrition time and ventilator use time of premature infants in the study group were all shorter than those in the control group, the differences were statistically significant (P＜0.05). After intervention, the feeding status of premature infants in the study group was better compared to the control group, the difference was statistically significant (P＜0.05). The incidence rate of feeding intolerance in the study group after intervention was lower than that in the control group, the difference was statistically significant (P＜0.05). There were no statistical differences in the body weight, body length and head circumference between the two groups of premature infants before intervention (P＞0.05). After intervention, the body weight, body length and head circumference of premature infants in the two groups were greater than those at birth, the differences were statistically significant (P＜0.05), and the body weight, body length and head circumference were greater in the study group than those in the control group, the differences were statistically significant (P＜0.05). The total incidence rate of complications in the study group was lower than that in the control group after intervention, the difference was statistically significant (P＜0.05). Conclusion The combination of position management based on infant position assessment tool and developmental supportive nursing is beneficial to enhancing the feeding tolerance, promoting the growth and development, and improving the clinical outcomes of premature infants. 2022 Vol. 29 (24): 166-169 [Abstract] ( 19 ) HTML (1 KB)  PDF (640 KB)  ( 23 ) 170 Study on the combined nursing for retinopathy of prematurity treated with intravitreal injection of anti -vascular endothelial growth factor drugs XU Yueyuan,LI Yingjie,ZHU Xuan,YOU Xiaohua Objective To investigate the clinical effect of combined nursing intervention in retinopathy of prematurity(ROP) treated with intravitreal injection of anti-vascular endothelial growth factor (VEGF) drugs. Methods A total of 60 infants with ROP admitted to Department of Ophthalmology, the First Hospital of Nanchang from January 2019 to December 2021 were selected as the research objects. They were divided into the observation group and the control group by random number table method, with 30 cases in each group. Both groups were treated with intravitreal injection of anti-VEGF drugs.The observation group received ward combined with operating room optimized nursing,and the control group received routine nursing intervention. The two groups were compared in terms of clinical effect, and the total incidence rates of adverse events such as dyspnea, asphyxia, gas accumulation in vitreous cavity, infection, retinal detachment and endophthalmitis. Results The total treatment response rate showed no statistically significant difference between the two groups (P＞0.05). The total incidence of adverse events in the observation group was lower than in the control group, with statistically significant difference (P＜0.05). Conclusion Combined nursing intervention for infants with ROP treated with intravitreal injection of anti-VEGF drugs can effectively reduce postoperative adverse events and improve the prognosis. 2022 Vol. 29 (24): 170-172 [Abstract] ( 19 ) HTML (1 KB)  PDF (665 KB)  ( 35 ) 173 Application effect of targeted psychological intervention nursing in female patients after pacemaker operation HUANG Yingmei,HONG Weixiang,YUAN Yuan,CHEN Yao,WEN Xiaocui,GONG Jing,CHEN Ying,LIU Yuanqing Objective Through analyzing the factors of patients′ psychological disorders, giving targeted psychological intervention nursing, to understand its application effect on female patients with pacemaker. Methods A total of 100 female patients with permanent pacemaker implanted in the Department of Cardiology of Jiangxi Provincial People′s Hospital from March 2020 to March 2021 were selected as research objects, they were divided into the control group and the observation group according to the random number table method, with 50 cases in each group. The control group was given routine nursing (disease knowledge guidance, pacemaker postoperative rehabilitation guidance, etc.), the observation group received targeted psychological intervention nursing on the basis of routine nursing. Self-rating depression scale (SDS), self-rating anxiety scale (SAS) and short form-36 health survey (SF-36) were used to evaluate and compare the conditions of patients in the two groups before surgery, 1 week, 1 and 3 months after surgery. Results At 1 week, 1 and 3 months after surgery, SAS scores and SDS scores of the observation group were lower than those of the control group, SF-36 scores of the observation group were higher than those of the control group, the differences were statistically significant (P<0.05). Conclusion Through analyzing the causes of psychological disorders in female patients with pacemaker and giving them targeted psychological intervention nursing can improve the psychological counseling effect of patients, shorten the time for patients to return to society,and improve their long-term quality of life. 2022 Vol. 29 (24): 173-176 [Abstract] ( 15 ) HTML (1 KB)  PDF (675 KB)  ( 19 ) 177 Application of continuous nursing based on parental care needs in premature infants with bronchopulmonary dysplasia WANG Jiaju,HUO Leying,LI Shilin Objective To explore the application effect of continuous nursing based on parental care needs in premature infants with bronchopulmonary dysplasia (BPD). Methods A total of 50 premature children with BPD and their parents(main caregivers) treated in Zhuhai Maternal and Child Health Hospital from July 2019 to June 2021 were selected as the research objects. They were divided into control group and experimental group according to random number table method, with 25 cases in each group. The control group was given routine nursing, and the experimental group implemented continuous nursing based on parental care needs on the basis of the control group. The disease cognition level, care burden, oxygen therapy time, weight after intervention and rehospitalization rate were compared between the two groups. Results There were no significant differences in disease cognition level and care burden score between the two groups before intervention (P>0.05). After the intervention, the disease cognition level of parents in the two groups was higher than that before the intervention, and the care burden was lower than that before the intervention, the differences were statistically significant (P<0.05). After the intervention, the disease cognition level of parents in the experimental group was higher than that in the control group, and the care burden was lower than that in the control group, the differences were statistically significant (P<0.05). At the same time, the duration of oxygen therapy in the experimental group was shorter than that in the control group, the rehospitalization rate was lower than that in the control group, and the weight after intervention was higher than that in the control group, the differences were statistically significant (P<0.05). Conclusion Continuous nursing based on parental care needs can improve the disease cognition level of parents of premature infants with BPD, reduce the care burden, promote the growth and development of children, shorten the time of oxygen therapy and reduce the rate of rehospitalization. 2022 Vol. 29 (24): 177-180 [Abstract] ( 24 ) HTML (1 KB)  PDF (674 KB)  ( 24 ) 181 Application of hospital-community-family linkage management in the secondary prevention in patients with acute ischemic stroke of endovascular treatment strategy ZHANG Chunzhen,GUO Dongyan,CHEN Liwen Objective To investigate the efficacy of hospital-community-family linkage management in the secondary prevention in patients with acute ischemic stroke (AIS) of endovascular treatment strategy. Methods A total of 96 AIS patients treated with endovascular therapy in Zhongshan Hospital Affiliated to Xiamen University from January 2019 to May 2020 were selected as the research objects. They were divided into experimental group and control group by random number table method, with 48 cases in each group. Patients in the experimental group were treated with hospitalcommunity-family three-way linkage mode, while patients in the control group were followed up routinely. The neurological function and health service utilization were compared between the two groups before and after the intervention.Results The modified Rankin scale (mRS) score of the experimental group was lower than that of the control group, and the difference was statistically significant (P<0.05). The number of emergency visits in the experimental group was less than that in the control group 6 months after discharge, and the difference was statistically significant (P<0.05). The number of outpatient visits in the experimental group was more than that in the control group 6 months after discharge,and the difference was statistically significant (P<0.05). There was no significant difference in the number of re-hospitalizations between the two groups 6 months after discharge (P>0.05). Conclusion The hospital-community-family linkage management provide continued care to patients after they discharged from hospital. It can improve the patients′ability of daily living and use of medical resources as well. 2022 Vol. 29 (24): 181-184-188 [Abstract] ( 17 ) HTML (1 KB)  PDF (707 KB)  ( 100 ) 185 Application effect of Internet-based medical-nursing integration mode in pediatric fracture KANG Luhua Objective To explore the application effect of Internet-based medical-nursing integration mode in pediatric fracture. Methods A total of 82 children with fracture admitted to Ganzhou Maternal and Child Health Hospital from May to December 2021 were selected as the research objects. They were divided into control group and observation group by random number table method, with 41 cases in each group. The children in the control group received routine nursing, while the children in the observation group received continuous nursing care for 2 weeks based on the combination of Internet-based medical and nursing integration model. The postoperative indicators, pain, negative emotions,postoperative complications, rehabilitation level and nursing satisfaction were compared between the two groups. Results The hospitalization time of the observation group was shorter than that of the control group, and the treatment cost was lower than that of the control group, and the differences were statistically significant (P<0.05). After 2 weeks of nursing, the scores of self-rating anxiety scale (SAS), self-rating depression scale (SDS) and visual analogue scale(VAS) of the two groups were lower than those before surgery, and the observation group was lower than the control group, and the differences were statistically significant (P<0.05). There was no significant difference in the total incidence of joint stiffness, ischemic muscle spasm and wound infection between the two groups (P>0.05). Two months after operation, the elbow range of motion (ROM) and Newcastle nursing service satisfaction scale (NSNS) scores of the observation group were higher than those of the control group, and the differences were statistically significant (P<0.05).Conclusion The application of Internet-based medical-nursing integration mode can improve postoperative pain, promote functional recovery and improve satisfaction evaluation in fractures children. 2022 Vol. 29 (24): 185-188 [Abstract] ( 20 ) HTML (1 KB)  PDF (673 KB)  ( 21 ) 189 Effect of medical collaborative intervention model based on risk assessment on patients with transient ischemic attack CAO Xia Objective To explore the effect of medical collaborative intervention model based on risk assessment on patients with transient ischemic attack. Methods A total of 100 patients with transient ischemic attack treated in the second hospital of Fuzhou from January to December were selected as the research object. They were randomly divided into the experimental group and the control group, with 50 cases in each group. Routine nursing was used in the control group and collaborative nursing intervention based on risk assessment was used in the experimental group. The self perceived burden, the ability of nursing disease intervention and the change of blood pressure were compared between the two groups, and the work quality of nurses in the two groups was compared. Results After intervention, the scores of physical burden, emotional burden and total scores of self-perceived burden in two groups were lower than those before intervention, and the scores of economic burden in two groups were higher than those before intervention, with statistically significant differences (P＜0.05). After intervention, the scores and total scores of self perceived burden in the experimental group were lower than those in the control group, with statistically significant differences (P＜0.05). After intervention, the scores and total scores of intervention indexes of main care diseases were higher than those in the control group, with statistically significant differences (P＜0.05). After intervention, the systolic blood pressure and diastolic blood pressure in two groups were lower than those before intervention, and the systolic blood pressure and diastolic blood pressure in the experimental group were lower than those in the control group, with statistically significant differences (P＜0.05). After intervention, the scores of nursing management quality in the experimental group were higher than those in the control group, with statistically significant differences (P＜0.05). Conclusion The medical collaborative intervention model based on risk assessment can improve the ability of patient care and disease intervention, improve the negative emotion and self feeling burden of patients, and improve the quality of life. 2022 Vol. 29 (24): 189-192 [Abstract] ( 19 ) HTML (1 KB)  PDF (640 KB)  ( 23 ) 193 Application effect of evidence-based nursing on patients with chronic obstructive pulmonary disease treated by intradermal acupuncture point combined with hand Taiyin lung by scraping WANG Yanfang Objective To analyze the application effect of evidence-based nursing on patients with chronic obstructive pulmonary disease (COPD) treated by intradermal acupuncture point combined with hand Taiyin lung by scraping.Methods A total of 60 COPD patients treated in Zhongshan Hospital of Traditional Chinese Medicine from December 2019 to March 2021 were selected as the study subjects, and they were divided into the control group and the treatment group according to random number table method, with 30 patients in each group. The two groups of patients were treated with intradermal acupuncture point combined with hand Taiyin lung scraping treatment, the control group was treated with routine nursing, and the treatment group was treated with evidence-based nursing intervention based on the control group, and the application effects of the two groups were compared. Results After intervention, the scores of clinical main symptoms and St George′s respiratory questionnaire (SGPQ) in the treatment group were lower than those in the control group, and the number of acute exacerbations within half a year in the treatment group was lower than that in the control group, with statistical significance (P＜0.05). The 6-min walking distance in the treatment group was longer than that in the control group, and the treatment compliance rate in the treatment group was higher than that in the control group, with statistical significance (P＜0.05). Conclusion Through the treatment of COPD patients with intradermal acupuncture point combined with hand Taiyin lung scraping treatment, at the same time with evidencebased nursing, can effectively alleviate the symptoms of COPD patients, improve respiratory function and quality of life,improve the ability of daily life of COPD patients, nursing effect is significant, worthy of further promotion. 2022 Vol. 29 (24): 193-196 [Abstract] ( 23 ) HTML (1 KB)  PDF (675 KB)  ( 37 )

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