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2016 Vol. 23, No. 2
Published: 2016-01-18
 
 
4 Influence of cyanidin from black rice on metabolism and kidney lesion in GK rats
DONG Bo;XU Xun;LIU Sheng-bing;ZHOU Xin-mei
Objective To investigate the influence of cyanidin on metabolismand and kidney lesion in GK rats. Methods 24 healthy male GK rats were divided randomly into two groups.Each group got 12 GK rats.Cyanidin group was fed in 10％glucose with cyanidin-3-glucoside（600 mg/L）.The blank control group was fed in 10％glucose only.The foodintake was detected each day and the weight,fasting plasma glucose,triglyceride and cholesterol were detected each week.All GK rats were killed after 8 weeks.The GHbA1c,kidney weight index and the degree of renal pathological injury was observed respectively. Results The food -intake,weight,plasma glucose,GHbA1c,triglyceride,cholesterol and kidney weight index in cyanidin group was lower than that of the blank control group respectively（P＜0.05）.The kidney pathological lesion in cyanidin group was significantly decreased too. Conclusion Cyanidin has benefitto diabetes mellitus through reduced the food -intake,weight,plasma glucose,GHbA1c,triglyceride and cholesterol.Senile diabetic nephropathy can also be prevented through cyanidin-3-glucoside.
2016 Vol. 23 (2): 4-7 [Abstract] ( 128 ) HTML (51 KB)  PDF  (0 KB)  ( 33 )
8 Content of stachydrine hydrochloride from Motherwort granule determined by high performance liquid chromatography-tandem mass spectrometry
LI Ming

Objective To establish a method of high performance liquid chromatography（HPLC）-tandem mass spectrometry determining the content of stachydrine hydrochloride from Motherwort granule. Methods The chromatographic conditions were Agilent SB-C18column（50 mm×2.1 mm,1.8 μm）,acetonitrile to 0.2％glacial acetic acid（70︰30）as the mobile phase,and a flow rate of 0.3 ml/min.Positive ion electrospray ionization（ESI＋）was applied for mass spectrometric detection under multiple reaction monitoring（MRM）mode.The monitored ions（m/z）was 144/58,144/84 respectively. Results The concentration of stachydrine hydrochloride being within 0.2 μg/ml to 10.0 μg/ml had a good linear relationship with the peak area.The r value was 0.9992,and the average recovery was 102.6％and the value of RSD was 1.5％（n＝6）. Conclusion The method is fast,simple,specific,and accurate in outcome,which can be used for quality control of Motherwort granule.
2016 Vol. 23 (2): 8-10 [Abstract] ( 161 ) HTML (48 KB)  PDF  (0 KB)  ( 36 )
11 Experimental study on simvastatin in prevention of steroid -induced femoral head necrosis
ZHANG Hui;YIN Li;ZHANG Yan-ru;Kaka AA Katiella;HAN Qi-cai
 Objective To investigate the prevention effects of simvastatin against steroid-induced femoral head necrosis and to discuss its mechanism. Methods 36 New Zealand white rabbits were randomly divided into three groups,each with 12 rabbits.Rabbits in group A were intramuscularly injected by dexamethasone 2.5 mg/（kg·d）,rabbits in group B were orally given simvastatin 20 mg/d plus intramuscularly injected by dexamethasone 2.5 mg/（kg·d）,and rabbits in group C were orally given simvastatin 20 mg/d.The change of blood lipid was detected at the 12thweeks and histological observation of femoral head was conducted at the 12thweeks when the rabbits were executed. Results Compared with group B and group C,the differences of serum cholesterol,triacylglycerol,and NO level of rabbits in group A was statistically significant respectively（P＜0.05）.There was no significant difference between group B and group C（P＞0.05）.As to the level of bone metabolic markers including NO,osteocalcin（OCN）,and tartrate resistant acid phosphatase（TRAP-5b）, there was statistically significant difference between group A and group B（P＜0.01）,and between group A and group C （P＜0.01）, but no significant difference between group B and group C（P＞0.05）.Histological observation showed osteonecrosis and trabecular destruction in group A,which was not observed in group B or group C. Conclusion Simvastatin can regulate the lipid and bone metabolism,lower the blood lipid,inhibit the destruction of bone cells,and prevent femoral head necrosis.
2016 Vol. 23 (2): 11-13转17 [Abstract] ( 159 ) HTML (47 KB)  PDF  (0 KB)  ( 35 )
14 Study on the HPLC fingerprint of Atalantia buxifolia
JIANG Li-juan;PI Sheng-ling;FANG Tie-zheng;YAO Jiang-xiong;XU Zhao-dong;LIN Li-mei
Objective To establish the HPLC fingerprint chromatogram of Atalantia buxifolia coupled with chemometrics means for the quality control of multi-batches of medicinal material. Methods The samples were analyzed on Kromasil 100-C18（250 mm×4.6 mm，5 μm）column with a acetonitrile（A）-0.5％acetic acid（B）as the mobile phase（0-30 min, 20％→50％A;30-70 min,50％→100％A）at a flow rate of 1.0 ml/min.The detective wavelength was 254 nm and the column temperature was at 35℃.12 samples was constructed for similarity evaluation,cluster analysis and principle component analysis. Results A specificity HPLC fingerprint spectrum was developed for Atalantia buxifolia,18 common peaks were indicated and 12 samples were divided into 5 groups. Conclusion With the combination of chemometrics means, the HPLC fingerprint chromatogram provides a method for evaluation of authenticity and quality control of Atalantia buxifolia,which is favorable to improve quality control of Atalantia buxifolia.
2016 Vol. 23 (2): 14-17 [Abstract] ( 149 ) HTML (52 KB)  PDF  (0 KB)  ( 29 )
18 Research progress of the application of open airway technology in cardiopulmonary resuscitation
LI Yi
It is very important to establish an open airway for effective pulmonary ventilation in cardiopulmonary resuscitation（CPR）,but there exist different kinds of technologies.With the improvement of the patient′s needs and the progress of medical technology,the open airway technology represented by the proseal laryngeal mask airway（PLMA）which aims to raise the CPR success rate is wildly used in clinic with its simplicity,efficiency and safety.This essay begins with the analysis of the four rescue measures-facemask pressure for ventilation, tracheotomy for ventilation,endotracheal intubation for ventilation and laryngeal airway for ventilation used in CPR,then comprehensively analyzes its history development,time and difficulty of operation,efficiency of ventilation and safety and finally summarizes the application of effective open airway in CPR.
2016 Vol. 23 (2): 18-20 [Abstract] ( 155 ) HTML (42 KB)  PDF  (0 KB)  ( 21 )
21 Esearch progress of dexmedetomidine on preventing shivering during intraspinal anesthesia
LUO Shuang-shuang;YAN Jue-ji;CHEN Can
Thermostasis is a critical factor to ensure the normal physiological function of human body.Shivering is a common complication which can be induced by versatility reasons during anesthesia.Shivering is a stress reaction in which the temperature regulating center orders the skeletal muscles to contract fast to increase body temperature,especially under intraspinal anesthesia.As a new selective α2-adrenergic receptor agonist.Dexmedetomidine with the sedation and analgesia effect,has high effectiveness on preventing shivering and optimizing the quality of intraspinal anesthesia.This paper reviews to investigate the effect of dexmedetomidine on preventing shivering during intraspinal anesthesia.
2016 Vol. 23 (2): 21-23 [Abstract] ( 159 ) HTML (46 KB)  PDF  (0 KB)  ( 36 )
24 Clinical study of laparoscopic hepatectomy on treating hepatic calculus
ZHANG Zhi-cheng
Objective To explore the feasibility of laparoscopic hepatectomy in patients with hepatic calculus in clinic. Methods Forty-eight patients with hepatic calculus from May 2012 to May 2014 in our hospital were recruited into the research,and were divided into two groups by a random number table.In control group,conventional partial hepatectomy was used,while in the observation group,laparoscopic hepatectomy was applied.The clinical cure rate,operation time,intraoperative amount of bleeding,recovery time of gastrointestinal function after surgery,time of being off bed,incidence of biliary fistula,and incidence of complications were studied and compared. Results The clinical cure rate in the observation group was 91.7％,and that was 83.3％in the control group,there was no statistically significant difference between two groups（P＞0.05）.The comparison of operation time,intraoperative amount of bleeding,recovery time of gastrointestinal function after surgery,time of being off bed,incidence of complications in the observation group had differences between two groups（P＜0.05）.The incidence of biliary fistula had no statistically significant difference between two groups（P＞0.05）. Conclusion For patients with hepatic calculus,application of laparoscopic hepatectomy can obtain a more remarkable effect and better safety,and presents with a clinical value for universal application in comparison with that by conventional partial hepatectomy.
2016 Vol. 23 (2): 24-25转28 [Abstract] ( 141 ) HTML (37 KB)  PDF  (0 KB)  ( 39 )
26 Clinical analysis of thoracoscopic surgery and thoracotomy in the treatment of lung cancer involved with chest wall
DING Chang-ming
Objective To compare the effect of thoracoscopic surgery and thoracotomy on treating lung cancer involved with chest wall. Methods From May 2010 to August 2012,66 patients who were suffered from lung cancer spreading to chest wall treated in our hospital were selected.They were randomly divided into observation group and control group.In the control group（n＝32）was used thoracotomy,while,the observation group（n＝34）was adopted thoracoscopic surgery. The effect in the two groups was compared. Results In the observation group,operation time,indwelling time of intrathoracic drain,and hospital stay were all shorter than those in the control group（P＜0.05）.The intraoperative amount of bleeding and postoperative total volume of drainage of chest fluid in the observation group were also less in comparison with those in the control group（P＜0.05）.The incidence of complications after surgery was greatly lower in the observation group than that in the control group（P＜0.05）.There was no significant difference in one-year or three-year survival rate in two groups（P＞0.05）. Conclusion Compared with thoracotomy,radical operation for lung cancer under thoracoscope obtains a considerable long-term therapeutic effect on treating patients with lung cancer spreading to chest wall at advantages of smaller trauma on body and higher surgical safety,which is worthy of promotion.
2016 Vol. 23 (2): 26-28 [Abstract] ( 154 ) HTML (40 KB)  PDF  (0 KB)  ( 30 )
29 Clinical analysis of 116 cases with type 2 diabetes complicated with subclinical hypothyroidism
LI Zi-zhen;WANG Mei
Objective To observe the clinical feature of patients with type 2 diabetes complicated with subclinical hypothyroidism　（SCH）and to analyze its possible effect. Methods The clinical data of 840 patients with type 2 diabetes hospitalized in the department of endocrinology of Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 1,2014 to October 31 were selected and retrospectively analyzed.Among 840 patients,those combined with SCH were divided into observation group（group A）and the other patients into control group（group B）. The age,course of disease,gender ratio,thyroid function,TgAb,TpoAb,blood lipid profile,and complications of diabetes in patients between two groups was compared respectively. Results Compared with group B,the female ratio（60.3％vs 49.2％）,TSH level [（6.44±4.57）mU/L vs（1.82±0.83）mU/L],TgAb level [（124.99±302.37）U/ml vs（23.19±80.47）U/ml], TpoAb level [（125.79±355.14）U/ml vs（20.95±108.85）U/ml],total CHOL level [（5.30±1.46）mmol/L vs（4.90±1.24）mmol/L], LDL-C level [（3.27±1.10）mmol/L vs（3.06±0.99）mmol/L] was higher and the incidence rate of combined CHD（39.7％vs 26.8％）,low extremity atherosclemsis disease（54.3％vs 43.4％）,diabetic retinopathy（DR）（28.4％vs 20.4％）,diabetic kidney disease（DKD）（31.9％vs 23.1％）and diabetic peripheral neuropathy（DPN）（50.0％vs 39.9％）was higher that of group A,and the level of FT4was lower [（14.37±3.27）pmol/L vs（15.74±2.98）pmol/L].Except for DR（P＝0.052）,the difference of above-mentioned index was all statistical （P＜0.05）. Conclusion Combined SCH may have an adverse effect on type 2 diabetic patients.Therefore,patients with type 2 diabetes,especially females,patients with higher thyroid antibody levels,patients with abnor-book=30,ebook=36mal blood lipid metabolism are suggested to screen thyroid function regularly. For patients with type 2 diabetes complicated with SCH,the incidence rate of complication of diabetes is higher and more attention should be paid on disease condition to reduce related risk.
2016 Vol. 23 (2): 29-32 [Abstract] ( 152 ) HTML (52 KB)  PDF  (0 KB)  ( 30 )
33 Impact of diabetes mellitus on prognosis of PCI therapy
XIE Jian-wei
Objective To observe the prognosis situation of diabetic patients accepted percutaneous coronary intervention（PCI）and to evaluate the impact of diabetes mellitus on prognosis of PCI. Methods Data of 583 patients conducted PCI in department of cardiology in Dashiqiao Central Hospital of Liaolin Province from July 2012 to June 2014 were retrospectively analyzed.Patients were divided into DM group（n＝152）and NDM　（n＝431）group by wether combined with diabetes mellitus or not.The main adverse cardiovascular events（MACE）incidence situation liked miocardial infarction and PCI operation again,coronary artery bypass surgery and death in after 1 year operation in two groups were recorded. Results 1 year mortality rate in DM group was 4.6％,and it was obviously higher than that of NDM group （0.7％）（P＜0.01）.Miocardial infarction rate again was 12.5％in DM group,and it was higher than that of NDM group （6.3％）（P＜0.01）.The incidence rate of total adverse cardiovascular event in DM group was 25.7％,and it was higher than that of NDM group（13.9％）（P＜0.01）. Conclusion The ratio of coronary heart disease patients with diabetes mellitus occurred MACE after PCI is higher.So,although patients are given successfully underwent PCI therapy,it still needs to attach importance to the further treatment of diabetes,and continuous pay attention to blood sugar and blood fat.
2016 Vol. 23 (2): 33-35 [Abstract] ( 138 ) HTML (38 KB)  PDF  (0 KB)  ( 28 )
36 Correlation research on serum C-peptide and atherosclerosis in patients with new-onset type 2 diabetes mellitus
WANG Li
Objective To explore the risk factor of atherosclerosis in patients with new-onset type 2 diabetes mellitus, and analyze the correlation and significance between serum C-peptide and atherosclerosis. Methods From November 2013 to November 2014,73 patients with new-onset type 2 diabetes mellitus visited our hospital for treatment were selected.According to whether there was atherosclerosis or not,they were divided into combination of atherosclerosis group （n＝31）and simple type 2 diabetes mellitus group（n＝42）.30 healthy people after physical examination were selected into healthy control group.The level of serum C-peptide in three groups were tested and the correlation between serum C-peptide and atherosclerosis was analyzed. Results The serum C-peptide level in simple type 2 diabetes mellitus group was obviously higher than that of healthy control group and combination of atherosclerosis group,and there was a statistical difference（P＜0.05）.There was a statistical difference of serum C-peptide level between combination of atherosclerosis group and healthy control group（P＞0.05）.There was a negative correlation between serum C-peptide level and degree of atherosclerosis（r＝-0.328,P＜0.05）.Decrease of serum C-peptide level was an independent risk factor in patients with new-onset type 2 diabetes mellitus complicated with atherosclerosis（P＜0.05）. Conclusion The level of serum C -peptide in patients with new -onset type 2 diabetes mellitus is closely related with complications of atherosclerosis,and decrease of serum C-peptide level may cause easily complication such as atherosclerosis and other vascular complication in patients with type 2 diabetes.
2016 Vol. 23 (2): 36-38 [Abstract] ( 159 ) HTML (37 KB)  PDF  (0 KB)  ( 43 )
39 Clinical value of detection and evaluation of serum cystatin C in early diagnosis of diabetic nephropathy for type 2 diabetes mellitus
WU Dan;GUAN Shuo;LI Lun
Objective To estimate the clinical value of serum cystatin C（Cys C）detection level in early diagnosis of diabetic nephropathy for type 2 diabetes mellitus and to provide clinical diagnosis basis for early diagnosis of diabetic nephropathy for type 2 diabetes mellitus. Methods 162 patients with type 2 diabetes mellitus from October 2014 to June 2015 received by our hospital were selected and they were divided into 3 groups according to urinary microalbumin（mAlb）,namely normal albuminuria group（mAlb＜30 mg/24 h,n＝68）,microalbuminuria group（mAlb 30～300 mg/24 h,n＝52）and clinical proteinuria group（mAlb＞300 mg/24 h,n＝42）.And healthy control 80 cases（normal control group）were selected randomly in healthy check-up center.The level of serum Cys C of all examinees was determined,and the level of blood urea nitrogen（BUN）,serum creatinine（SCr）and urinary microalbumin（mAlb）was determined respectively and simultaneously.The test results were counted and analyzed. Results The level of Cys C and mAlb were the lowest in normal control group and clinical proteinuria group was the highest in all examinees.There was a statistical difference of level of serum Cys C and urinary mAlb between the other 3 groups and normal control group（P＜0.05）.In addition to normal control group,there was a statistical difference of the level of Cys C and urinary mAlb among the other three groups（P＜0.05）. There was a significant positive correlation between the level of Cys C and urinary mAlb level in microalbuminuria group and clinical proteinuria group of（r＝0.107,0.152,P＜0.05）. Conclusion The level of Cys C is closely related to the degree of early renal damage in patients with type 2 diabetes mellitus,and it has clinical value in early diagnosis of diabetic nephropathy.
2016 Vol. 23 (2): 39-41转46 [Abstract] ( 169 ) HTML (46 KB)  PDF  (0 KB)  ( 42 )
42 Clinicopathological features and prognosis of colorectal cancer with ascites
WANG Hong-xu;ZHANG Ji-dong;LI Dong-ping;LU Yan-xing;LI Rui
Objective To investigate the prognostic results of clinicopathological data in patients with colorectal cancer combined with ascites and analyze the prognosis. Methods The clinicopathological and follow up study data of 139 patients combined with ascites and 400 patients without ascites between October 1999 and January 2005 in our department were retrospectively analyzed and evaluated the prognosis between them by SPSS 19.0. Results Single factor analysis revealed that the prognostic of patients combined with ascites were associated with the factors,such as intestinal obstruction,pelvic metastatic nodal,peritoneal implantation,liver metastasis,viscera invasion,tumor location,radical degrees,tumor type,depth of infiltration,and histological classification（P＜0.01）.Peritoneal implantation（OR＝1.781,95％CI＝1.131-2.804）,pelvic metastatic nodal（OR＝3.211,95％CI＝1.196-8.623）,liver metastasis（OR＝3.127,95％CI＝1.777-5.502）,depth of infiltration（OR＝2.789,95％CI＝1.015-7.665）were of important factors in radical prostatectomy of colorectal cancer combined with ascites by binary Logistic analysis;survival analysis revealed that overall survival were different in whether colorectal cancer combined with ascites（1,3,5,10 year of survival rate respectively:80％,67％,60％, 41％vs 58％,48％,38％,27％）and resection and lymphnodenectomy contribute to improve overall survival（P＜0.05）. Conclusion Patients with colorectal cancer combined with ascites indicate poor prognostic results.Patients with colorectal cancer combined with ascites underwent dissection and lymphnodenectomy can significantly improve the survival rates.
2016 Vol. 23 (2): 42-46 [Abstract] ( 155 ) HTML (50 KB)  PDF  (0 KB)  ( 34 )
47 The therapeutic effect of rmh-TNF combined cisplatin in treating lung cancer with malignant pleural effusion
HU Tao;CHEN Xiao-lin;HUANG Yu-min;TAO Yu-jian
Objective To observe the therapeutic effect and adverse reactions of recombinant mutant human tumor necrosis factor（rmh-TNF）combined cisplatin in the treatment of lung cancer with malignant pleural effusion. Methods Sixty patients of lung cancer with malignant pleural effusion from January 2013 to December 2014 in our hospital were chosen and randomly divided into treatment group and control group.Treatment group were injected intrapleurally with rmh-TNF combined cisplatin at a dose of 2×106U and 30 mg after complete drainage,once a week;control group were injected intrapleurally with cisplatin at a dose of 30 mg,once a week,the effect and adverse reactions were observed. Results Among the treatment group,14 patients were complete response（CR）,12 patients were partial response（PR）and 4 patients were no change（NC）,the overall response rate was 86.7％,among the control group,8 patients were CR,8 patients were PR and 14 patients were NC,the overall response rate was 53.3％,the difference was statistically significant （P＜0.01）.Common adverse reactions were common chest pain,the incidence of gastrointestinal reaction（malignant,vomiting）in treatment group was 43.3％（13/30）,23.3％（7/30）respectively, and was 33.3％（10/30）,30.0％（9/30）in control group,the difference was no statistically significant（P＞0.05）.The incidence of fever in treatment group was 46.7％（14/ 30）,and was 16.7％　（5/30）in control group,the difference was statistically significant（P＜0.05）. Conclusion The rmh-TNF combined cisplatin is effective in the treatment of lung cancer with malignant pleural effusion,and with slide adverse reactions.
2016 Vol. 23 (2): 47-49 [Abstract] ( 155 ) HTML (43 KB)  PDF  (0 KB)  ( 37 )
50 Application of tubular gastric reconstruction inⅡ,Ⅲtype gastric esophagus integration carcinoma operation
YIN Qing-hui;ZENG Xiang-tai;WANG Xue-zhong;YE Bin1LI Cai-sheng
Objective To evaluate the clinical effect of tubular gastric reconstruction inⅡ,Ⅲtype gastric esophagus integration carcinoma operation. Methods 144 cases ofⅡ,Ⅲtype gastric esophagus integration carcinoma patients from December 2009 to December 2013 were divided into two groups by digestive tract reconstruction mode.Patients in traditional group（n＝76）were conducted esophagus-residual stomach anastomosis.Patients in tubular gastric group（n＝68）were conducted esophagus- tubular stomach anastomosis.The incidence rate of postoperative gastroesophageal reflux and reflux esophagitis were observed. Results Both of basic data and clinical pathological feature of patients in two groups had no statistical significance（P＞0.05）.35.5％patients had acid reflux symptoms after esophagus-residual stomach anastomosis in traditional group,16.1％patients appeared that after esophagus-tubular stomach anastomosis in tubular gastric group,the difference was statistically significant（P＝0.041）.22.3％patients were diagnosed as reflux esophagitis after esophagus-residual stomach anastomosis in traditional group,7.5％patients were diagnosed as reflux esophagitis after esophagus-tubular stomach anastomosis in tubular gastric group,the difference was statistically significant（P＝0.038）. Conclusion Comparing with esophagus-residual stomach anastomosis,esophagus- tubular stomach anastomosis can obvious alleviate acid reflux and reflux esophagitis of patients after operation and enhance life quality. It is worth to popularize in clinical.
2016 Vol. 23 (2): 50-52 [Abstract] ( 125 ) HTML (39 KB)  PDF  (0 KB)  ( 36 )
53 Analysis of the application effect of complete colon resection for colon cancer resection
LI Han
Objective To study the therapeutic effect of complete colon resection for colon cancer resection. Methods 160 patients with colon cancer who were diagnosed in our hospital from September 2014 to September 2015 were selected and divided into two groups.The control group（n＝80）was treated with conventional surgical resection,while the treatment group（n＝80）was given complete resection of the colon.Curative effect,clinical indicators and survival rate of two groups were compared and analyzed. Results The effective rate of the treatment group was 80.00％,the control group was 56.25％;the average bleeding volume in the treatment group was（144.36±54.56）ml,the number of lymph nodes was 35,the average bleeding volume in the control group was（362.33±67.81）ml,the number of lymph nodes was 14;the survival rate of the treatment group after 3 years was 75.00％,the local recurrence rate was 5.00％,the rates of control group were 63.75％and 30.00％;there were 3 cases of postoperative infection,3 cases of residual tumors in the treatment group,6 cases of postoperative infection,6 cases of anastomotic leakage,12 cases of residual tumor residual in the control group,the differences were all statistically significant（P＜0.05）. Conclusion Complete colon resection for colon cancer resection is the greatest extent to remove the lymph nodes,improve the long-term effect and improve the quality of life of patients.
2016 Vol. 23 (2): 53-55 [Abstract] ( 125 ) HTML (41 KB)  PDF  (0 KB)  ( 35 )
56 Curative effect comparison of five kinds of hemostatic operation on intractable postpartum hemorrhage and reason analysis of hemostasis failure
WANG Lin
Objective To explore the clinical effect of five kinds of hemostatic operation treating intractable postpartum hemorrhage,and analyze the cause of hemostasis failure. Methods From January 2010 to December 2013,180 patients suffering from intractable postpartum hemorrhage in our hospital were selected as research group.According to different hemostatic methods,they were divided into uterine cavity packing（n＝60）,strap-uterine binding（n＝36）,uterine compression suture（n＝24）,ascending and descending branches of uterine artery ligation（n＝24）,pelvic arterial embolization（n＝36）.The hemostatic effect and cause of failure was observed respectively. Results The operation time in pelvic arterial embolization was obviously shorter than that of other four kinds of method,amount of bleeding during surgery in pelvic arterial embolization was greatly less than that of other four kinds of method,which displayed a statistical difference（P＜0.05）.There were 24 cases for hemostasis failure,mainly due to scarred uterus,placenta implantation,and coagulation dysfunction,and it accounted for 50.0％,25.0％,and 25.0％respectively. Conclusion Five other four kinds of method on intractable postpartum hemorrhage is feasible,especially pelvic arterial embolization with advantages of short operation time and little amount of bleeding.Meanwhile,scarred uterus,placenta implantation,and coagulation dysfunction are the causes leading to hemostasis failure.The reasonable hemostasis method should be selected based on the condition of pregnant woman.
2016 Vol. 23 (2): 56-58 [Abstract] ( 159 ) HTML (39 KB)  PDF  (0 KB)  ( 25 )
59 The value analysis of ethacridine amniotic injection combined with mifepristone for induction of labor in midpregnancy
SUN Yi-wen
Objective To investigate the clinical value of ethacridine amniotic injection combined with mifepristone for induction of labor in midpregnancy. Methods 120 cases with induction of labor in midpregnancy Received by our hospital from January 2012 to March 2015 were selected and they were divided into two group according to the random number method,and there were 60 cases in each group.Control group was given ethacridine for amniotic cavity injection,while observation group was given ethacridine for amniotic cavity injection combined with mifepristone tablet.The surgery-related cases,complication and so on was compared between two groups. Results The placental delivery time, the time of medication and contraction,and total time of induced labor in observation group was obviously shorter than that of control group,vaginal bleeding amount in observation group was less than that of control group（P＜0.05）,the proportion of residual placenta in observation group was lower than that of control group,induction success rate in observation group was higher than that of control group（P＜0.05）.The proportion of nausea and vomiting,abdominal pain and distension,dizziness and headache between two groups had no statistical difference（P＞0.05）. Conclusion Ethacridine for amniotic cavity injection combined with mifepristone for induction of labor in midpregnancy can effectively elevate the speed of labor progress and reduce bleeding amount during operation and complications and adverse reactions,and improve the success rate of labor induction.
2016 Vol. 23 (2): 59-61 [Abstract] ( 147 ) HTML (40 KB)  PDF  (0 KB)  ( 31 )
62 Influence of personalized delivery model on delivery outcome in primipara
LI Li-ting;XIAO Jin-hong;HE Xiu-ling
Objective To explore the influence of personalized delivery model on delivery outcome in primipara. Methods From October 2012 to December 2014,200 full-termprimiparae to infanticipate received by our hospital were selected as research group.They were evenly divided into two groups using the random number table method.In control group,traditionaldelivery model for delivery was used.Primiparae were sent to delivery room for nursing midwifery when their cervix opened to 3 cm.In observation group,personalized delivery model namely accompany responsibility midwifery model in the whole delivery was used for midwifery.To be specific,on admission to hospital,primipara was accompanied by one senile and one standby midwife in the whole delivery including antenatal delivery guidance,accompanied labor during delivery,and breast feeding guidance after delivery.The duration of labor,the incidence rate of cesarean section,fetal distress in uterus,postpartum depression for puerpera,and Apgar score in neonate between two groups was compared respectively. Results In observation group,time of the first stage and second stage was shorter than that of control group respectively,ans postpartum hemorrhage amount was less than that in control group,the incidence rate of cesarean section,fetal distress in uterus,postpartum depression for puerpera was lower than that of control group respectively,and there was a statistical difference（P＜0.05）. Conclusion Personalized delivery model can effectively shorten stage of labor in primiparae,and reduce the incidences of cesarean section,fetal distress in uterus,and postpartum depression for puerpera,reduce postpartum hemorrhage amount,and improve neonatal Apgar score,which is worthy of clinical application and promotion.
2016 Vol. 23 (2): 62-64 [Abstract] ( 118 ) HTML (43 KB)  PDF  (0 KB)  ( 27 )
65 Application of HR-HPV,TCT combined with cervical biopsy under electronic colposcope respectively in the diagnosis of precancerous lesion of uterine cervix and cervical cancer
YAN Qi;HUANG Wen-jin;ZENG Chao-yi;WEN Hong-lei
Objective To explore the diagnostic value of high-risk human papillomavirus（HR-HPV）test,thinprep cytologic test（TCT）combined with cervical biopsy under electronic colposcope respectively in the diagnosis of precancerous lesion of uterine cervix and cervical cancer. Methods Four hundred medical records of TCT,electronic colposcope and cervical biopsy from January to December 2013 and 400 medical cases by HR-HPV,electronic colposcope and cervical biopsy from January to December 2014 were retrospectively analyzed,and the positive rate of two kinds of inspection method was compared. Results For the TCT,electronic colposcope and cervical biopsy,the positive rate of detection was 10.75％（43/400）,while for HR-HPV,electronic colposcope and cervical biopsy,the positive rate of detection was 11.75％　（47/400）,and there was no statistical difference between two kinds of inspection method（P＞0.05）. Conclusion HR-HPV,electronic colposcope and cervical biopsy, and TCT,electronic colposcope and cervical biopsy have higher detection rate on precancerous lesions of uterine cervix and cervical cancer,which are beneficial for early detection and treatment of precancerous lesion of uterine cervix and cervical cancer,and are relatively ideal examination method.
2016 Vol. 23 (2): 65-67 [Abstract] ( 132 ) HTML (43 KB)  PDF  (0 KB)  ( 32 )
68 Effect observation of laparoscope treating 208 patients with endometriosis
ZHANG Yong-ping
Objective To explore the effect of laparoscope surgery treating endometriosis. Methods Typical cases from endometriosis patients received by our hospital from January 2008 to April 2014 were selected as research group.Cases were divided into different therapy group,208 cases（study group）were treated with laparoscopic surgery therapy,while 200 cases（control group）were treated with routine open surgery therapy.Clinical effect between two groups was compared. Results The disease remission rate in study group（96.2％）was obviously higher than that of control group （90.0％）,and recurrence rate（1.4％）was obviously lower than that of control group（P＜0.05）. Conclusion The effect of laparoscopic surgery treating endometriosis is obvious,and it can improve the clinical symptom and prognosis,reduce recurrence rate of disease.It is worthy of reference.
2016 Vol. 23 (2): 68-70 [Abstract] ( 121 ) HTML (44 KB)  PDF  (0 KB)  ( 36 )
71 Curative effect of recombinant human interferon α-2a suppository combined with Baofukang suppository in the treatment of chronic cervicitis complicated with human papilloma virus infection
QIU Jin-zhu;LIU Hong-yu
Objective To explore the effect of recombinant human interferon α-2a suppository combined with Baofukang suppository treating chronic cervicitis complicated with human papilloma virus（HPV）infection. Methods From March 2012 to December 2014,80 patients definitely diagnosed as chronic cervicitis complicated with HPV infection treated by our hospital were selected as research group.They were evenly divided into intervention group and control group in random.In control group,Baofukang suppository was used,while in intervention group,on the basis of control group,recombinant human interferon α-2a suppository was added.The duration time of abnormal secretion,wound healing time,HPV negative conversion ratio,clinical curative efficacy,and incidence rate of adverse reaction in patients between two groups was compared respectively. Results In intervention group,duration time of abnormal secretion and wound healing time was obviously shorter than that of control group（P＜0.05）.HPV negative conversion ratio after 4 and 8 months therapy was 52.5％and 80.0％in intervention group,and it was obviously higher than that of control group（30.0％and 57.5％）（P＜0.05）.The total effective rate in intervention group was 92.5％,and it was obviously higher than that of control group（80.0％）（P＜0.05）.There was no significant difference of occurrence rate of adverse reaction between two groups（P＞0.05）. Conclusion recombinant human interferon α-2a suppository combined with Baofukang suppository in the treatment of chronic cervicitis complicated with HPV infection has a remarkable effect,and it is worthy of clinical promotion and application.
2016 Vol. 23 (2): 71-73 [Abstract] ( 141 ) HTML (44 KB)  PDF  (0 KB)  ( 24 )
74 Effect observation of aerosol inhalation combined with laser therapy in the treatment of asthmatic disorder in children
LAI Hua-ji
Objective To explore the effect of aerosol inhalation combined with laser therapy treating asthmatic disorder in children. Methods From February 2013 to February 2015,130 children with asthmatic disorder treated by our hospital were selected as research group and evenly divided into two groups in random.In control group,compound ammonium bromide solution and budesonide suspension was used,while in observation group,on the basis of control group, laser therapy of dual wavelength optical fiber was added.Disappearance time of wheezing rale and moist rale,panting, and coughing,hospital stay,and level of immune globulin indexes including IgM,IgA,and IgG was observed and compared respectively. Results In observation group,disappearance time of wheezing rale,moist rale,panting and coughing, and hospital stay [（3.08±1.15）d,（2.72±0.93）d,（3.85±0.46）d,（5.36±1.65）d] was shorter than that in control group[（4.76±1.58）d,（4.04±1.35）d,（5.33±1.22）d,and（7.59±2.03）d respectively,which displayed statistical difference（P＜0.01）.In observation group,IgM,IgA,and IgG [（1.65±0.45）g/L,（2.78±0.55）g/L,and（10.76±1.56）g/L] was higher than that in control group [（0.98±0.32）g/L,（1.75±0.41）g/L,（7.87±1.30）g/L],which displayed statistical significance（P＜0.01）. Conclusion Aerosol inhalation combined with laser therapy can enhance alleviation of symptoms and signs and improve immunoresistance in the treatment of asthmatic disorder in children.
2016 Vol. 23 (2): 74-75转78 [Abstract] ( 120 ) HTML (37 KB)  PDF  (0 KB)  ( 39 )
76 Application value of sequential therapy of estrogen and progesterone treating missed abortion in patients after dilatation and curettage
ZHOU Wei;HUANG Juan;XIONG Ju-ying;LU Hong-mei
Objective To explore the application value of sequential therapy of estrogen and progesterone treating missed abortion in patients after dilatation and curettage. Methods 150 patients with missed abortion given dilatation and curettage received by our hospital from June 2014 to June 2015 were selected.Patients were divided into control group and study group according to the random number table method.Patients in control group were given routine antibiotics to anti-infection after dilatation and curettage.Patients in study group were given adjuvant treatment of sequential therapy of estrogen and progesterone on the basis of routine anti-infection.Postoperative incidence rate of intrauterine adhesions,vagnal bleeding time and endometrial repair situation（endometrial thickness and return time of menstruation）was compared in patients between two groups. Results Incidence rate of intrauterine adhesions in study group （3.8％）was obviously lower than that of control group（16.7％）,and the difference was statistical significance（P＜0.05）. Vagnal bleeding time had no statistical difference between two groups（t＝-1.0834,P＞0.05）.Endometrial thickness in study group was obviously bigger than that of control group,and return time of menstruation in study group was shorter than that of control group,and there was a statistical difference（P＜0.05）. Conclusion Sequential therapy of estrogen and progesterone treating missed abortion in patients after dilatation and curettage has better clinical curative effect.It can fast and effectively recovery endometrium.It is suitable for clinical popularization and application.
2016 Vol. 23 (2): 76-78 [Abstract] ( 146 ) HTML (39 KB)  PDF  (0 KB)  ( 38 )
79 Application effect of collagen sponge in after remoal of maxillary teeth
ZHANG Yuan
Objective To discuss the application value of collagen sponge in after remoal of maxillary teeth. Methods 280 dental extraction patients from January 2011 to February 2012 of our hospital were selected.Patients were randomly divided into experimental group and control group,and each group was140 cases.Patients in experimental group were filled the collagen sponge after dental extraction.Patients in control group were not given any drugs or material.Clinical effect in two groups were observed and analyzed. Results The incidence of alveolalgia and other complications in experimental group were significantly lower than that of control group.The total effective rate in experimental group was 87.1％significantly higher than that was 60％in control group,and the difference was statistical significance（P＜0.05）. Conclusion Collagen sponge has good clinical effect in prevention alveolalgia after remoal of maxillary teeth.It can decrease the incidence of alveolalgia and worth to energeticallypopularize and extensive application in clinical.
2016 Vol. 23 (2): 79-81 [Abstract] ( 128 ) HTML (42 KB)  PDF  (0 KB)  ( 33 )
82 Applied effect of transmission adjustable appliance in teeth micromaxillary deformity correction
ZHOU Yi-ning;RONG Zhu-ping;HE Lin-xia;LUO Hong;XIE Xu-guang
Objective To explore the applied effect of transmission adjustable appliance in teeth micromaxillary deformity correction. Methods 80 dentognathic deformity patients from January 2013 to December 2014 of our hospital were selected.Patients were randomly divided into control group and experimental group,and each group was 40 cases.Patients in experimental group were treated with transmission adjustable appliance,and patients in control group were treated with treatment esrtuary bow.The treatment sustained time and serious index in two groups were compared and counted. Results The therapy effect in experimental group was better than that of control group.The treatment sustained time in experimental group and control group was respectively（13.22±1.01）months and（21.1±1.69）months（t＝12.145, P＜0.05）.The width of maxillary first premolar and gap were respectively（41.25±1.24）mm and（55.22±1.35）mm,which were better than that were（36.51±2.01）mm and（52.33±1.21）mm in control group（t＝12.236,P＜0.05;t＝12.584,P＜0.05）.All of the above had statistical significance（t＝11.652,P＜0.05）. Conclusion Using transmission adjustable appliance in teeth micromaxillary deformity correction can decrease the treatment cycle and increase treatment effect.It is worth to popularize.
2016 Vol. 23 (2): 82-84 [Abstract] ( 119 ) HTML (49 KB)  PDF  (0 KB)  ( 31 )
85 Aesthetic effect of zirconia crown on the anterior tooth
XU Ning;SONG Xin;WANG Cui-yan
Objective To investigate the clinical results of zirconia crown on the anterior tooth. Methods 100 cases （235 anterior teeth）of anterior tooth restoration in our hospital,According to the use of different materials,Divided into observation group（50 cases,106 anterior teeth）and control group（50 cases,129 anterior teeth）.The control group was dental restoration with nickel-chromium alloy-porcelain crown,The observation group was dental restoration with zirconia single crowns,evaluate comprehensively the clinical efficacy and safety of zirconia all-ceramic anterior crowns with nickel chromium alloy porcelain crown for the restoration of the front teeth. Results The observation group of satisfaction rate was 100％,and control group of satisfaction rate was 79.1％.The observation group not change of color,the control group color change incidence rate was 23.3％,differences between the two groups（P＜0.01）. The observation group of gingivitis incidence rate was 18.9％,the control group was 45.0％,observation group than that of control group（P＜0.01）.There is no gap between the patients in the observation group and the abutment teeth,the edge of the edge is in a level,observation group than that of control group（P＜0.01）or（P＜0.05）. Conclusion Porcelain-veneered zirconia single crown contribute to the aesthetic of the anterior teeth.
2016 Vol. 23 (2): 85-87 [Abstract] ( 131 ) HTML (47 KB)  PDF  (0 KB)  ( 31 )
88 Clinical effect of different operation methods in treating expansion stage cataract secondary glaucoma continuous high intraocular pressure
DONG Bao-ying;LI Zhi-hui;TANG Xue-fu;DUAN Yong-bo
Objective To explore the clinical effect of different operation methods in treating expansion stage cataract secondary glaucoma continuous high intraocular pressure. Methods 22 continuous high intraocular pressure patients （22 eyes）,diagnosed as expansion stage cataract secondary glaucoma in our hospital and intraocular pressure more than 5.33 kPa after treated with maximal dosage anti-glaucoma agents for 2 to 3 days from February 2014 to December were selected.Patients were randomly divided into two groups.10 cases in experimental group were treated with vitreous puncture pumping fluid combined with cataract ultrasonic emulsification plus artificial lens implantation.12 cases in control group were treated with anterior chamber puncture combined with cataract ultrasonic emulsification plus artificial lens implantation.Postoperative eyesight,intraocular pressure,changes of anterior chamber depth and incidence of operation complications were observed and compared in two groups after operation. Results Postoperative eyesight,intraocular pressure,changes of anterior chamber depth of all patients improved after vitreous aspiration or anterior chamber puncture fluid combined with cataract ultrasonic emulsification plus artificial lens implantation,but there was no obvious difference compared with two groups（P＞0.05）.The operation complications incidence rate in vitreous puncture pumping fluid group was 20％,lower than that was 58.33％in anterior chamber puncture group,and the difference was statistical significance（P＜0.05）. Conclusion Both of cataract ultrasonic emulsification plus artificial lens implantation combined with vitreous puncture pumping fluid or anterior chamber puncture can reduce the expansion stage cataract secondary glaucoma continuous high intraocular pressure and enhance eyesight.But the former is more safety and can decrease the incidence rate of operation complications.
2016 Vol. 23 (2): 88-90转93 [Abstract] ( 138 ) HTML (43 KB)  PDF  (0 KB)  ( 35 )
91 Effect comparison between partial pulpotomy and traditional pulpotomy in treating young permanent teeth with exposed pulps in crown fracture
WANG Jun;LIN Ze-yuan
Objective To explore the clinical effect of partial pulpotomy and traditional pulpotomy in treating young permanent teeth crown pulp. Methods 60 young permanent teeth patients with exposed pulps in crown fracture（68 sick teeth）from July 2011 to July 2014 of our hospital were respectively analyzed.Patients were randomly divided into two groups experimental group and control group,and each group was 30 cases（34 sick teeth）.Patients in experimental group were treated with partial pulpotomy of Cvek method,patients in control group was treated with traditional routine pulpotomy.The clinical effect was compared between two groups.Tooth disease examination,pulp vitality test,root development status of tooth,situation of inside and outside absorption and root canal calcification and pathological changes situation of root tip were routine observed 2 weeks,1 month,3 months and 6 months after operation. Results The success rate in experimental group was higher than that of control group,the success rate in experimental group and control group were respectively 94.1％and 88.2％,and the difference was statistical significance（P＜0.05）.It was found that root development status of tooth in experimental group was better than that of control group at postoperative reexamination,and the difference was statistical significance（P＜0.05）. Conclusion Both of partial pulpotomy and traditional pulpotomy can effectively cure the young permanent teeth with exposed pulps in crown fracture,but the clinical prognosis effect is good in the former and can promote the root development.
2016 Vol. 23 (2): 91-93 [Abstract] ( 116 ) HTML (40 KB)  PDF  (0 KB)  ( 32 )
94 Therapeutic effect of trabeculectomy and Ex-PRESS glaucoma filtration on ocular traumatic secondary glaucoma
CHEN Li-na;ZOU Ji-xin
Objective To explore the efficiency of trabeculectomy and Ex-PRESS glaucoma filtration in patients suffered ocular traumatic secondary glaucoma. Methods Use prospective randomized controlled clinical trials choose 40 eyes of traumatic glaucoma were randomly divided into two groups.All patients were assigned to groups A and B according the different therapy.Group A（21 eyes）was treated with Ex-PRESS glaucoma filtration device implantation. Group B（19 eyes）was treated with trabeculectomy.The last follow-up time was 1 year after surge.The postoperative visual acuity,intraocular pressure and success rate were analyzed. Results The ratio of improved visual acuity in group A was significantly higher than that of group B（P＜0.05）.Compared with that before operation,intraocular pressure both in group A and group B significantly decreased（P＜0.05）,but the average of intraocular pressure in group A was lower than that of group B during the long term follow up（P＜0.05）.Definitely sucess and fail rate was statistical difference between group A and group B（P＜0.05）.Definitely success in group A was higher than that of group B.Fail rate in group A was lower than that of group B. Conclusion Ex-PRESS glaucomafiltration device implantation has the advantages ofsimpleness,safety,minimally invasive,short learning curve for ocular traumatic secondary glaucoma,Ex-PRESS glaucoma filtration is worth clinical application.
2016 Vol. 23 (2): 94-96转99 [Abstract] ( 117 ) HTML (47 KB)  PDF  (0 KB)  ( 29 )
97 Effect observation of pranoprofen combined with polyethylene glycol eye drops in treating keratoconjunctivitis sicca
LIU Shen-zhi
Objective To explore the clinical effect of pranoprofen combined with polyethylene glycol eye drops in treating keratoconjunctivitis sicca. Methods 80 keratoconjunctivitis sicca patients who treated in our hospital were selected.Patients were randomly divided into study group and control group,and each group was 40 cases.Patients in control group were simply treated with polyethylene glycol eye drops and patients in study group were treated with pranoprofen combined with polyethylene glycol eye drops.Clinical effect in two groups after treatment were compared and analyzed. Results After treatment,the cure rate and effective rate in study group were respectively 52.5％and 97.5％, which were respectively 37.5％and 87.5％in control group,and the difference was statistical significance（P＜0.05）.The break-up time of tear film　（BUT）had no statistical significance in two groups before treatment（P＞0.05）.After treatment, the BUT in study group was obvious higher than that of control group,and the difference was statistical significance（P＜0.05）.The cure rate of patients with conjunctival congestion jealous in study group was 70％,which was 14.29％in control group,and the difference was statistical significance（P＜0.05）. Conclusion For keratoconjunctivitis sicca patients,the effect of using pranoprofen combined with polyethylene glycol eye drops is more obvious than simply using polyethylene glycol eye drops,and it should be popularize application in clinic.
2016 Vol. 23 (2): 97-99 [Abstract] ( 123 ) HTML (38 KB)  PDF  (0 KB)  ( 34 )
100 Effects observation on intravenous injection of tramadol at emergence of general anesthesia in prevention of agitation
ZHOU Qian;LV Dong-sen;YUAN Cheng-cheng;KANG Li;LUO Fen;LIU Huan-jie;LIU Hua
Objective To observe the therapeutic effects and safety of tramadol in emergence agitation of general anesthesia. Methods 200 patients with ASA gradeⅠtoⅡtreated by upper abdominal surgeries in our hospital from January 2011 to January 2014 were selected and randomly divided into two groups（100 patients in each group）.Patients in the observation group were treated by intravenous injection of tramadol 1.5 mg/kg,while patients in the control group were only intravenously injected by normal saline 2 ml.The emergence agitation,heart rates and mean arterial pressure （MAP）before and after operation,and at tracheal extubation and 10 min after extubation were recorded.The incidence of adverse event was statistically analyzed. Results Compared with the baseline values before anesthesia,after intervention, the heart rates and MAP at tracheal extubation were statistically significant enhanced（P＜0.05）.Compared with the control group,the incidence of severe agitation in the observation group was significantly reduced（χ2＝4.073,P＜0.05）.The incidences of nausea and vomiting in the observation group and control group was 10％（10/100）and 7％　（7/100）respectively,without statistically significant difference between two groups. Conclusion Tramadol has favorable clinical effect and safety in treatment of emergence agitation of general anesthesia,which is worthy to be promoted.
2016 Vol. 23 (2): 100-102 [Abstract] ( 114 ) HTML (43 KB)  PDF  (0 KB)  ( 25 )
103 Observation on the sedative effect of intranasal dexmedetomidine used for children undergoing debridement suture surgery in department of emergency
SHI Bao-zhu;SHI Xiu-xia;YANG Ming-hua;XU Zai-chao;JI Shi-qiang
Objective To observe the effect of intranasal dexmedetomidine used for children undergoing debridement suture surgery in department of emergency. Methods Forty children undergoing debridement suture surgery in department of emergency of our hospital from January 2014 to March 2015 were selected,and were randomly divided into two groups,20 cases in each group.The children in group A were treated with 10％chloral hydrate as enema（0.5 ml/kg）, while the group B were treated with intranasal dexmedetomidine（2 μg/kg）,debridement suture surgery undergoing with 2％lidocaine after sedation.Heart rates,respiratory rates and oxyhemoglobin saturations before and after treatment between two groups were monitored and compared.The sedative effect between two groups was observed.Ramsay scores was obtained.The times to calm down and to wake up and the adverse reactions were recorded. Results The debridement suture surgery was completed between two groups after treatment.The sedative effect of group B was better than that of group A.The waking up time in group B was shorter than that of group A.No adverse reaction occured in group B,one child was found with nausea and vomiting in group A. Conclusion Intranasal dexmedetomidine used for children undergoing debridement suture surgery in department emergency has the advantages of taking action and recovery fast, good sedative effect and less incidence of adverse reactions than that with chloral hydrate,which is worth clinical popularizing and applying.
2016 Vol. 23 (2): 103-105 [Abstract] ( 121 ) HTML (40 KB)  PDF  (0 KB)  ( 30 )
106 Impact of dexmedetomidine on analgesia and sedation effect during sufentanil anesthesia induction
XIAO Hong-xia
Objective To explore the impact of dexmedetomidine on analgesia and sedation effect of patients with gynecological surgery anesthesia induction period by low dosage sufentanil. Methods 60 gynecological operation patients from May 2014 to May 2015 were divided into two groups,and each group was 30 cases.Patients in control group were treated with sufentanil（0.4 μg/kg）and 10 ml saline mix intravenous drug delivery,patients in observation group were treated with sufentanil（0.4 μg/kg）and diluted to 50 ml sufentanil（1 μg/kg）.Nacotrend index were respectively tested at the time of before treatment（T1）,after application saline or dexmedetomidine（T2）,the highest alert level（T3）and after application sufentanil（T4）.The time-taked that NTI values filled to the lowest at T3-T4was compared between two groups. The value of right forearm 0.1 cm2probe tenderness pain threshold and pain tolerance threshold at T1and T4were recorded.The changes of RR level was recorded between two groups. Results The TNI value in observation group at T2was obvious lower than that of control group,and the difference was statistical significance（P＜0.05）.The time-taked that NTI values filled to the lowest in observation group was shorter than that of control group（P＜0.05）.The increase of PPT and PTO values in observation group at T4was obvious higher than that of control group respectively（P＜0.05）.After application of sufentanil,the RR in observation was slower than that of control group（P＜0.05）. Conclusion On the basis of low dosage sufentanil,combined with dexmedetomidine is helpful to enhance the analgesic effect and promotes the sedative drugs work to speed up.But may be increases risk of respiratory inhibition by sufentanil,so clinical should careful use.
2016 Vol. 23 (2): 106-108转111 [Abstract] ( 135 ) HTML (50 KB)  PDF  (0 KB)  ( 34 )
109 Analysis on effects of general anesthesia and epidural anesthesia on postoperative cognitive function in elderly orthopedic patients
LI Hai-quan
Objective To investigate the effects of general anesthesia and epidural anesthesia on postoperative cognitive function in elderly orthopedic patients. Methods 118 cases of elderly orthopedic patients in our hospital from October 2014 to June 2015 were randomly divided into research group and control group,each were 59 cases.The research group were received general anesthesia and epidural anesthesia.The control group were received general anesthesia.The postoperative recovery time,extubation time,response time,postoperative mental state and cognitive dysfunction incidence rate were compared. Results The postoperative recovery time,extubation time and response time of research group was respectively（29.3±4.6）,（30.6±4.1）,（31.7±3.9）min,which was shorter than that of control group respectively（P＜0.05）.Postoperative 4,12,24 h,mental state of research group was better than that of control group respectively（P＜0.01）.The cognitive dysfunction incidence rate of research group was lower than control group（P＜0.05）. Conclusion General anesthesia combined with epidural anesthesia can effectively reduce postoperative cognitive dysfunction in elderly orthopedic patients.It′s better than general anesthesia alone.
2016 Vol. 23 (2): 109-111 [Abstract] ( 132 ) HTML (39 KB)  PDF  (0 KB)  ( 30 )
112 Application effect of flurbiprofen axetil combined with dezocine in intravenous analgesia after gynecologic surgery
TAN Zhi-lin
Objective To analyze the application effect of flurbiprofen axetil combined with dezocine in intravenous analgesia after gynecologic surgery. Methods 100 patients with ASAⅠtoⅡdegree and without anesthesia taboo,elective surgery and needed postoperative intravenous analgesia patients from August 2014 to June 2015 of our hospital were selected.Patients were randomly divided into three groups,Group A was simply flurbiprofen axetil control group, group B was simply dezocine group and group C was flurbiprofen axetil combined with dezocine group.The clinical analgesia effect among three groups was compared. Results Visual analogue scale at different time points after operation of group C compared with group A and group B,the difference was not statistically significant（P＞0.05）.24 h postoperative analgesia score In group C was（2.31＋1.40）points,which was lower than（2.59＋1.74）points,（2.61＋1.75）points respectively in group A and group B,with no statistical differenc（P＞0.05）.The incidence of adverse reactions in group C was lower than that of group A and group B respectively,the difference was statistically significant（P＜0.05）. Conclusion With the aid of flurbiprofen axetil combined with dezocine,the intravenous analgesia effect is obvious using in gynecologic surgery postoperative analgesia.It can reduce the pain degree of patients and with slight adverse reaction.It is worth to use for its significant meaning.
2016 Vol. 23 (2): 112-114 [Abstract] ( 106 ) HTML (42 KB)  PDF  (0 KB)  ( 37 )
115 Effect observation of live combined bacillus subtilis and enterococcus faecium enteric-coated capsules combined with Congrongtongbian oral liquid in the treatment of constipation after cerebral apoplexy
HUANG Qun;ZHOU Yan-fen
Objective To observe the effect of live combined bacillus subtilis and enterococcus faecium enteric-coated capsules combined with Congrongtongbian oral liquid in the treatment of constipation after cerebral apoplexy. Methods 60 patients with constipation after cerebral apoplexy in our hospital from January to December in 2014 were selected and randomly divided into study group and control group,each group had 30 cases.The control group was given foundation treatment,the study group was received live combined bacillus subtilis and enterococcus faecium enteric-coated capsules and Congrongtongbian oral liquid on the basis of control group.The treatment effects in two groups were compared after 1 and 2 weeks of treatment. Results The clinical efficacy in study group was better than that of the control group after 1 week or 2 weeks of treatment（P＜0.05）,and there was no serious adverse reaction.The incidence of abdominal pain and abdominal distension in study group was lower than that of control group（P＜0.05）,but there was no significant difference between the two groups of the diarrhea rate（P＞0.05）. Conclusion Live combined bacillus subtilis and enterococcus faecium enteric-coated capsules combined with Congrongtongbian oral liquid in the treatment of constipation after cerebral apoplexy can improve intestinal micro ecological and promote intestinal peristalsis,and can quickly and safely improve the symptoms of constipation.
2016 Vol. 23 (2): 115-117 [Abstract] ( 132 ) HTML (41 KB)  PDF  (0 KB)  ( 36 )
118 Application analysis on cephalosporin antibacterial agents in pneumology department of our hospital from January 2012 to December 2014
GUO Xiao-ning;HE Wei;YANG Li-fu
Objective To explore the application situation of cephalosporins antibacterial agents in pneumology department of our hospital and to provide reference to clinical rational drug use. Methods Defined daily dose system（DDDs）was applied,and the sales amount and DDDs of cephalosporins used in pneumology department of our hospital from January 2012 to December 2014 were ranked and analyzed. Results In recent 3 years,the sales amount of cephalosporins used in pneumology department of our hospital was showed an increasing tendency,while DDDs nearly held the line.In 2012 and 2013,cephalosporins of generation 1 was the main aspect,while in 2014,DDDs of cephalosporin generation 2 and 3 was far more than generation 1,and the cephalosporins of generation 2 leaded the sales amount and DDDs. Conclusion The application of cephalosporins in pneumology department of our hospital is relatively reasonabl,but still need to further standardize,to contral or slow the development of bacterial drug resistance,and to facilitate the safety,effectivene and economical efficiency in use of cephalosporin.
2016 Vol. 23 (2): 118-120转123 [Abstract] ( 125 ) HTML (41 KB)  PDF  (0 KB)  ( 29 )
121 Impact of sitagliptin phosphate on blood lipid of patients with type 2 diabetes
LU Ying;ZOU Shui-lan;KONG Xia
Objective To observe the impact of sitagliptin phosphate on blood lipid of patients with type 2 diabetic. Methods 40 patients with type 2 diabetic admitted into our hospital from July 2013 to November 2014 were selected. All patients were treated with sitagliptin phosphate（100 mg,once a day）for 24 weeks.The changes of fasting blood glucose,2 hours postprandial hyperglycemia,glycosylated hemoglobin,body weight index,blood lipid and blood uric acid in patients were observed before and after treatment. Results Compared with treatment for 12 weeks and before treatment, the level of fasting blood glucose,postprandial hyperglycemia,glycosylated hemoglobin was decreased（P＜0.05）,body weight index,total cholesterol,triglyceride,high density lipoprotein cholesterol,low density lipoprotein cholesterol and blood uric acid had no obvious change（P＞0.05）.Compared with treatment for 24 weeks and before treatment,the level of fasting blood glucose,postprandial hyperglycemia,glycosylated hemoglobin,total cholesterol,triglyceride and low density lipoprotein cholesterol was obvious decreased（P＜0.05）,but body weight index,high density lipoprotein cholesterol and blood uric acid had no obvious change（P＞0.05）. Conclusion Sitagliptin phosphate can effective control blood glucose of patients with type 2 diabetic and improve blood lipid level.
2016 Vol. 23 (2): 121-123 [Abstract] ( 116 ) HTML (34 KB)  PDF  (0 KB)  ( 31 )
124 Clinical effect of gamma globulin combined with methylprednisolone in children with acute severe Mycoplasma pneumoniae pneumonia
YU Bai-yu
Objective To investigate the clinical effect of gamma globulin combined with methylprednisolone in children with acute severe Mycoplasma pneumoniae pneumonia（MPP）. Methods 80 children with acute severe MPP in our hospital from May 2013 to January 2015 were selected and randomly divided into the observation group（45 cases）and the control group（35 cases）.The control group was accepted the treatment of azithromycin,the observation group was received the treatment of gamma globulin combined with methylprednisolone.The clinical curative effect and the disappearance time of cough,fever time,pulmonary rales disappeared time,chest X-ray film recovery time in two groups were compared. Results The total effective rate in observation group was 93.4％,which was significantly higher than 71.4％of control group,the difference was statistically significant（P＜0.05）.The disappearance time of cough,fever time,pulmonary rales disappeared time,chest X-ray film recovery time in observation group was significantly shorter than the control group,the differences were statistically significant（P＜0.05）. Conclusion The treatment of gamma globulin combined with methylprednisolone can significantly improve the clinical symptoms of children with acute severe MPP.It is curative effect is remarkable,and can popularized in clinical.
2016 Vol. 23 (2): 124-126 [Abstract] ( 112 ) HTML (38 KB)  PDF  (0 KB)  ( 38 )
127 Clinical effect of Gongxuening capsule combined with progesterone capsule in the treatment of perimenopausal dysfunctional uterine bleeding
ZHOU Chun-qiu;ZHANG Yi-bei;YANG Chun;SHI Jin-yan
Objective To explore the clinical effect of Gongxuening capsule combined with progesterone capsule in the treatment of perimenopausal dysfunctional uterine bleeding. Methods 60 cases with perimenopausal dysfunctional uterine bleeding from January 2013 to January 2014 in our hospital were selected and randomly divided into the treatment group and the control group,30 cases in each group.The treatment group was treated with Gongxuening capsule combined with progesterone capsule,the control group was only treated with progesterone capsule.1 course was 3 periods for two groups.Recent hemostatic efficacy,degree of endometrial thickness and recurrence rate of dysfunctional uterine bleeding was compared in two groups before and after treatment respectively. Results The total effective rate of hemostatic efficacy in the treatment group was 90.0％,which was higher than 83.3％in the control group,with significant difference（P＜0.05）.The endometrial thickness after treatment of the two groups was thinner than that before treatment,with significant difference（P＜0.05）.The endometrial thickness after treatment in the treatment group was thinner than that in the control group,with significant difference（P＜0.05）.The improvement rate of the prolonged menstruation symptoms in the treatment group was 93.3％,which was higher than 70.0％in the control group,with significant difference（P＜0.05）. The improvement rate of the dripping bleeding in the treatment group was 100.0％,which was higher than 79.2％in the control group,with significant difference（P＜0.05）.The recurrence rate of the treatment group was lower than that of the control group,with significant difference（P＜0.05）. Conclusion The efficacy of Gongxuening capsule combined with progesterone capsule in the treatment of perimenopausal dysfunctional uterine bleeding is significant better than that of progesterone capsule.
2016 Vol. 23 (2): 127-130 [Abstract] ( 113 ) HTML (54 KB)  PDF  (0 KB)  ( 29 )
131 Influence of levamisole combined with Dangguibuxue decoction on immune function of adult nephrotic syndrome patient
TANG Lan-hua;XUE Shao-qing
Objective To explore the influence of levamisole combined with Dangguibuxue decoction on immune function of adult nephrotic syndrome patient. Methods 200 nephrotic syndrome patients from January 2010 to October 2014 in our hospital were selected and randomly divided into the control group and the observation group,100 cases in each group.The control group was given routine western medicine treatment,the observation group was given integrated Chinese and western therapy.The clinical effect,immune function index and the incidence rate of adverse reaction in two groups was compared. Results The total effective rate in the observation group was 94.0％,which was higher than 75.0％inthecontrolgroup,withsignificantdifference（P＜0.05）.Thelevelof IgGand IgAintheobservationgroupafter treatment was higher than that before treatment and in the control group,with significant difference（P＜0.05）.The level of CD3 in the observation group after treatment was lower than that before treatment and in the control group,the level of CD4 and CD4/CD8 in the observation group after treatment was higher than that before treatment and in the control group,with significant difference（P＜0.05）.The incidence rate of adverse reaction and recurrence rate in the observation group was lower than that in the control group,with significant difference（P＜0.05）. Conclusion The effect of levamisole combined with dangguibuxue decoction in the treatment of nephrotic syndrome is significant,which can effective improve immune function,reduce the incidence rate of adverse reaction,it is worthy of clinical promotion and application.
2016 Vol. 23 (2): 131-133 [Abstract] ( 112 ) HTML (47 KB)  PDF  (0 KB)  ( 36 )
134 Investigation analysis of health status in cervical cancer patients
FENG Qian-qian;CHEN Ying;CHEN Li-jun;HUANG Ying-fan
Objective To explore the health status of the patient with cervical cancer,to provide the basis for the corresponding intervention measures. Methods 183 cases with cervical cancer from October 2014 to February 2015 in our hospital were selected as the research group,and the health status was analyzed. Results There was significant difference in the constituent ratio of marital status,working status,complication,way of paying,nationality,educational level and relapse respectively（P＜0.05）.The score of all 8 dimensions of health status including physiological function,physiological competency,body pain,total health status,vigor level,social function,emotional function and mental health of the patient was lower than that of the score of national norm,with significant difference（P＜0.05）. Conclusion The health condition of cervical cancer patient is not optimistic,and the quality of life is low.Health care workers should implement the corresponding intervention measures to improve the patient′s self health management ability,promote their physical and mental health,improve their quality of life.
2016 Vol. 23 (2): 134-136转140 [Abstract] ( 109 ) HTML (43 KB)  PDF  (0 KB)  ( 26 )
137 Demography and clinical feature analysis of emergency treatment patients with severe mental illness
YI Huan-wen;JIANG Ling-peng;ZHANG Zhen-wen
Objective To explore the demography and clinical feature of emergency treatment patients with severe mental illness,and to provide reference base for emergency disposal of such patients in the future. Methods 283 severe mental illness patients underwent emergency disposal in community from June 2013 to December 2014 in our hospital were selected as the research group.The risk behavior grading was conducted by severe mental illness treatment management specification.Related data analysis of emergency disposed patients were conducted by using self-made questionnaire. Results In the proportion of emergency disposal patients,grade 3 was the highest,accounted for 34.63％,and grade 5 was the lowest,accounted for 5.3％.In the age structure,from 15 to 54 years old of two groups were most.In the marital status,the component ratio of hospital admission of unmarried patients in two groups were highest,respectively accounted for 50.00％and 51.02％.In the family income,the component ratio of hospital admission of the low-income patients in two groups were highest,respectively accounted for 58.09％and 55.78％.In the educational level,the component ratio of hospital admission of the junior middle school and the following patients in two groups were most,respectively accounted for 66.91％and 70.75％.In the disease course,the component ratio of hospital admission of less than or equal to 5 years patients was more than that of more than 5 years patients.Patients with the disease in two groups were more of schizophrenia,and the symptoms were more with behavior disorder.There was significant difference in the admission number,type of dosing and insight between the two groups（P＜0.01）. Conclusion Understanding the demography and clinical features of emergency treatment patients has positive meaning for effective execution emergency disposal and reducing incidence of risk behavior.
2016 Vol. 23 (2): 137-140 [Abstract] ( 118 ) HTML (43 KB)  PDF  (0 KB)  ( 34 )
141 Investigation analysis of periodontal status in hospitalized patients with type 2 diabetes in Luzhou city
ZHOU Cong;TAN Hong
Objective To explore the prevalence of periodontal diseases in patients with type 2 diabetes in Luzhou city and analyze its influence factor. Methods 198 hospitalized patients with type 2 diabetes from January 2012 to December 2013 in our hospital were selected as the research group.General information,education,smoking,alcohol consumption and blood sugar were investigated.Periodontal probing depth（PD）,attachment loss（AL）,sulcus bleeding index（SBI）and simplified oral hygiene index（OHI-S）of 6 index teeth were examined. Results The morbidity of periodontitis in 198 diabetic patients was 100％.The number of periodontitis in mild degree and moderate to severe degree was 79 cases（39.9％）and 119 cases（60.1％）.There was significant difference in varied gender,education,location,smoking and alcohol consumption in diabetic patients′periodontitis（P＜0.05）. Conclusion The morbidity of periodontitis in hospitalized diabetic patients is high from 2012 to 2013 in Luzhou city,and type 2 diabetic patients should pay attention to prevention and treatment of periodontal diseases.
2016 Vol. 23 (2): 141-143 [Abstract] ( 117 ) HTML (34 KB)  PDF  (0 KB)  ( 7 )
144 Investigation of cognition status of esophageal cancer prevention and treatment knowledge in Nanao island community residents
LIU Lian-zhen
Objective To investigate and analyze the cognition of esophageal cancer prevention and treatment knowledge in Nanao island community residents in order to point out the direction of propaganda and education in future. Methods 401 local community residents participated in esophageal cancer screening from 5 communities in Nanao island from August 2012 to December 2012 were selected as the research group.Homemade questionnaire as a research tool was used,cognitive status of esophageal cancer prevention and treatment knowledge in local residents was investigated. Results During the investigation of high risks factors of esophageal cancer cognition,the correct rates of three high risk factors included chronic inflammation of esophagus,preference for pickled vegetables or remaining food at previous night,and being fond of very hot food by urban residents in Nanao island were highest,accounted for 21.9％, 21.4％and 20.9％respectively.During the investigation of cognition status of esophageal cancer prevention knowledge, the top three cognition rate were what are symptoms of esophageal cancer at early stage,drinking alcoholic liquid and smoking always being prone to esophageal cancer,and participating in general investigation actively when esophageal cancer occurred in relatives,and the cognition rate was 23.4％,22.7％and 21.7％respectively.Television and internet were the main ways for people to obtain disease knowledge,followed by print media and health education lectures. Conclusion Cognition rate of high risk factor of esophageal cancer and its prevention and treatment knowledge by Nanao island community residents is not high,and propaganda and education of relative disease knowledge should be strengthened in future,especially implementation of activities like blackboard newspaper in community and education lectures,etc. should be paid great attention.
2016 Vol. 23 (2): 144-146 [Abstract] ( 116 ) HTML (40 KB)  PDF  (0 KB)  ( 31 )
147 Investigation analysis on psychological health status of primary hospital staff of Yongchuan district in Chongqing city
YANG Shi-ya;JIANG Rui-qiong;WU Xiao-ying
Objective To explore the psychological health status of primary hospital staff of Yongchuan district in Chongqing city. Methods 604 primary hospital staff from July 2014 to December in Yongchuan district of Chongqing city were selected as the research group,the questionnaire survey were carried out by using symptom checklist 90 （SCL-90）,and the psychological health status was analyzed. Results The total score of SCL-90 and the factor score such as somatization,anxiety and depression in 604 primary hospital staff was lower than that in the national norm score,with significant difference（P＜0.05）.The factor score of hostility in the male primary hospital staff was lower than that in the female,with significant difference（P＜0.05）. The factor score of anxity in primary hospital stsff above the age of 35 was higher than that from 18 to 35 years old,with significant difference（P＜0.05）.The was significant difference in the total score of SCL-90 and thefactor score of such as interpersonal sensitivity,delusion,depression,hostility,anxiety and obsessive-compulsive of the primary hospital staff between the different seniority（P＜0.05）.There was significant difference in the factor score of interpersonal sensitivity,hostility,anxiety and additional items between different professional title（P＜0.05）.There was no significant difference in the total score of SCL-90 and the score of other factor between different positions. Conclusion The primary hospital staff of Yongchuang District in Chongqing city have a higher level of psychological health,however,there is significant difference in different gender,age,seniority,professional title and position.
2016 Vol. 23 (2): 147-150 [Abstract] ( 122 ) HTML (48 KB)  PDF  (0 KB)  ( 33 )
151 Drug withdrawal analysis in gastroenterology ward in a top-three hospital in Tianjin city
WANG Ying;MA Ying-li
Objective To explore the current status and reason of drug withdrawal in gastroenterology ward of our hospital. Methods 280 patients from December 1st2014 to February 6th2015 were selected as the research group,the drug withdrawal data was recorded by Excel software.By drawing Pareto chart,the primary and secondary factors of returning drugs was analyzed. Results There were 582 pieces of drug withdrawal in total,and the most proportion was injection and oral administration next.The Pareto chart showed the main factors of drug withdrawal were adjustment of treatment （56.53％）and discharge（23.54％）,and the secondary factor was refusing treatment or examination. Conclusion Factor of drug withdrawal in hospital are diverse,and targeted rectification measures should be drafted aiming at drug withdrawal and strengthening rational drug use,which protects patient′s safety,reduce medical disputes hazards and improve the quality of medical services.
2016 Vol. 23 (2): 151-153 [Abstract] ( 121 ) HTML (41 KB)  PDF  (0 KB)  ( 42 )
154 Investigation of the immune prevention status and hepatitis B virus infection for preschool children in the Jiangcheng district of Yangjiang city
LIN Ru-mei;CHEN Wen-feng;ZOU Hui-xiang
Objective To explore the status of hepatitis B virus infection and hepatitis B vaccination among preschool children in Jiangcheng district of Yangjiang city. Methods 12 174 preschool children aged 3～6 in 21 public and private kindergartens in Jiangcheng district of Yangjiang city from April 2013 to April 2015 were selected and divided into grodeⅠ, gradeⅡand gradeⅢaccording to vaccination status of hepatitis B vaccine,the test data of hepatitis B virus serum markers（HBsAg,Anti-HBs）. Results In the 12 174 preschool children,the positive rate of HBsAg and Anti-HBs was 0.74％and 86.74％respectively.The positive rate of HBsAg was 0.84％in male and 0.64％in female,there was no significant difference between different genders（P＞0.05）.The positive rate of HBsAg in gradeⅠwas lower than that gradeⅡand gradeⅢ,the positive rate of HBsAg in gradeⅡwas lower than that in gradeⅢ,with significant difference（P＜0.05）.The positive rate of Anti-HBs in gradeⅠwas higher than that gradeⅡand gradeⅢ,the positive rate of Anti-HBs in gradeⅡwas higher than that in gradeⅢ,with significant difference（P＜0.05）. Conclusion The infection rate is lower in preschool children in Jiangcheng district of Yangjiang city,and the rate of hepatitis B vaccine immunization and the positive rate of protective antibody（anti-HBs）in the serum are higher.
2016 Vol. 23 (2): 154-156 [Abstract] ( 147 ) HTML (41 KB)  PDF  (0 KB)  ( 39 )
157 Investigation of awareness rate of gastrointestinal injury caused by glucocorticoid and non-steroidal anti-inflammatory drugs in community population in Foshan city
DENG Liang;FAN Zhao-hao;LI Shu-fang;LAO Wu-jian
 Objective To get known the awareness degree of gastrointestinal injury caused by glucocorticoid and nonsteroidal anti-inflammatory drugs（NSAIDs）by community population in order to provide a basis for popularizing community health education. Methods By cluster sampling in October 2014,1200 people were surveyed of some community,Lunjiao street of Shunde district in Foshan city.The outcome of these surveyed questionnaire was statistically analyzed. Results There were 1200 questionnaires delivered in total,and effective ones were 1168 in recycle.In male,there were 560 cases,while the rest was female.Among these effective cases,14 people once were given glucocorticoid,accounted for 1.2％.No one was given the glucocorticoid more than one month.There were 62 people who knew the gastrointestinal injury caused by glucocorticoid,and the awareness rate was 5.3％,the males were 23 case（4.1％）, and the female were 39 cases（6.4％）.There was no significant difference in the awareness rate of the gastrointestinal injury caused by glucocorticoid between the different gender（P＞0.05）.Among these 62 people,45 ones from high educational background knew the gastrointestinal injury caused by glucocorticoid,and the awareness rate was 9.2％,while in low educational background,there were only 17 ones,and the awareness rate was 2.5％.There was significant difference in the awareness rate of the gastrointestinal injury caused by glucocorticoid between the different educational background（P＜0.05）.Among these effective surveyed people,all of them was given NSAIDs.There were 42 people who took these drugs for more than one month,accounted for 3.5％.These NSAIDs were mainly used for prevention and treatment of cardiovascular and cerebrovascular diseases and osteoarticular diseases.There were 85 people who knew the gastrointestinal injury caused by NSAIDs,and the awareness rate was 7.2％,the male were 34 cases（6.1％）,and the female were 51 cases（8.4％）.There was no significant difference in the awareness rate of the gastrointestinal injury caused by NSAIDsbook=158,ebook=164between the different gender（P＞0.05）.Among high educational background population,there were 64 ones who knew the gastrointestinal injury caused by NSAIDs,and the awareness rate was 13.1％.In low educational background,21 people knew that,and the awareness rate was 3.1％. There was significant difference in the awareness rate of the gastrointestinal injury caused by by NSAIDs between the different educational background（P＜0.05）. Conclusion Compared with glucocorticoid,usage rate of NSAIDs in community population is higher,and some of the elder need to take for a long time.In comparison with high educational background people,the awareness rate of gastrointestinal injury in people of low educational background is lower,which needs to intensify health promotion and education aiming at avoiding side effects like gastrorrhagia,peptic ulcers and gastrointestinal perforation,etc..
2016 Vol. 23 (2): 157-160 [Abstract] ( 118 ) HTML (52 KB)  PDF  (0 KB)  ( 8 )
161 Research on mobile internet medical service pattern in conventional hospitals
LI Ya-jing;YU Ying
Conventional hospitals in China consistently provide medical service,health care,recovery and consultation services to patients by the guidance of "focus on the sickness".However,the service pattern of conventional hospitals now has a great distance from current fast pace of life and convenient service patterns of other industries.As the service concept of hospitals gradually converts to "focus on the demand of patients",the following problems of medical service of conventional hospitals are revealed:low efficiency of hospital operation,long waiting time of patients,uneven distribution and use of medical resource,low quality of medical service,lack of smooth medical-seeking passage in many areas,and heavy burden of health management for chronic diseases.In this thesis,a whole set of solutions to satisfy the demand of patients to the greatest extent by mobile internet medical service pattern was proposed practically.In this pattern,approaches including intelligent medical service,remote consultation,health management,and remote health education can improve the level and quality of national medical service,relieve doctor-patient relationship,promote national health,and promote medical education.
2016 Vol. 23 (2): 161-163转166 [Abstract] ( 122 ) HTML (43 KB)  PDF  (0 KB)  ( 46 )
164 Practical exploration the project management in boosting hospital spiritual civilization construction
XU Li-ting;LI Jing;XIA Xiu-fang;HUANG Jian-jun;LUO Zhang
Spiritual civilization construction work is the important carrier to improve hospital core competence,is the important way to promote coordinated development and comprehensive progressof the hospital.Our hospital selects "care for the patient" and "care for employees" as the theme to carry out the project bidding,project approval, monitoring and evaluation of spiritual civilization.On the concept stands out "masscharacter" and pays attention tothree combinations;on the management stands out "normative" and pays attention to three guides;on the practicestands out "productively" and promotes the three harmony,which inspiring endogenous power of employees to involve in the construction of spiritual civilization,improving the connotationquality of civilization create work,creatively exploring the long-term mechanism of spiritual civilization construction under the new situation and it achieves good results.
2016 Vol. 23 (2): 164-166 [Abstract] ( 103 ) HTML (38 KB)  PDF  (0 KB)  ( 33 )
167 Discrete analysis and counter measures of clinical nurse anxiety on the basis of Probit model
YANG Jia-ai;ZHENG Feng-lian;HUANG Mei-ying
Nurses as an ordinary and special profession in today′s society,face with the pressure from many sides.Most of the clinical nurses shows different degrees of psychological anxiety.Related Literature have a lot of research for that. But most of them are based on the qualitative research of data statistics,and the quantitative research is less.This article will be on the basis of the preliminary questionnaire survey data,setting up discrete choice Probit model to empirical analyze the related factors that affecting the clinical nurses psychological anxiety degree and then draws quantitative and qualitative conclusions.Putting forward reasonable suggestions on the basis of analysis influence.
2016 Vol. 23 (2): 167-169 [Abstract] ( 102 ) HTML (46 KB)  PDF  (0 KB)  ( 35 )
170 Impact of extended nursing intervention in anti-virus treatment compliance of patients with chronic hepatitis B
KONG Shaung-chan;XIE Chu-ling;ZHENG Zhi-xin;SU Shu-fen
Objective To explore the impact of extended nursing intervention in anti-virus treatment compliance of patients with chronic hepatitis B. Methods According to whether the implementation of extended nursing service,46 patients with chronic hepatitis B admitted into our hospital from January 2009 to December 2010 were selected as control group,and 49 patients with chronic hepatitis B from January 2011 to June 2013 were selected as experimental group. Two groups were given routine nursing and health education during hospitalization,and were given health guidance at discharged.The experimental group was given extended nursing intervention after discharged,and extended service archives was established.Two groups were followed up for 12 months. Related knowledge mastered degree and antivirus treatment compliance in two groups was inspected by questionnaire survey. Results The understanding level of patients to chronic hepatitis and anti-virus treatment,dug treatment compliance in experimental group were higher than those of control group（P＜0.01）. Conclusion Extended nursing intervention can enhance the understanding level of patients with chronic hepatitis B to chronic hepatitis and anti-virus treatment and treatment compliance,and can reduce the adverse reaction and complications.
2016 Vol. 23 (2): 170-172转175 [Abstract] ( 123 ) HTML (44 KB)  PDF  (0 KB)  ( 44 )
173 Effect of family visit for the patients with schizophrenia
LIU Yong-hua
Objective To explore effect of family visit for the patients with schizophrenia. Methods 160 schizophrenia patients who were recovered discharged from March 2013 to June 2014 in our hospital were divided into study group （n＝80）and control group（n＝80）by flipping a coin randomized method,control group was given the home self-management mode,study group was given family visit,intervention time lasted all 6 months.After study,the state of illness of the two groups were compared using BPRS,the deterioration rate and recurrence rate were compared in the two groups. Results Before family visit,the score of BPRS in study group was（24.35±6.28）scores,that was（24.51±6.21）scores in control group,there was no significant difference between two groups（t＝0.16,P＞0.05）;after family visit,the score of BPRS was（26.89±7.12）scores in study group,which was lower than the score of BPRS in control group of（31.84±8.25）scores（t＝4.06,P＜0.01）. Conclusion Family visit can maintain the state of an illness of schizophrenia patients,reduce relapse,improve rehabilitation.
2016 Vol. 23 (2): 173-175 [Abstract] ( 110 ) HTML (44 KB)  PDF  (0 KB)  ( 32 )
176 Application effect of high quality nursing in patients with atrial fibrillation
ZU Zhan-xia;YIN Xiao-ting;YAO Wei-hua
Objective To explore the application effect of high quality nursing in patients with atrial fibrillation. Methods 66 patients with atrial fibrillation treated in our hospital from October 2013 to October 2014 were selected and randomly divided into conventional group and research group,with 33 cases in each group.In the conventional group,basic nursing was used,while in the research group,high quality nursing was adopted.The nursing satisfaction,hospital stay and incidence of complications in two groups were compared. Results The nursing satisfaction in research group was 96.97％,which was higher than 84.85％of conventional group（P＜0.05）.The hospital stay in research group was（6.12± 0.23）d,which was shorter than（7.36±0.33）d of conventional group,but the difference between two groups was no significan（P＞0.05）.The incidence of complications in research group was 15.15％,which was lower than 39.39％of conventional group（P＜0.05）. Conclusion High quality nursing has good effect in patients with atrial fibrillation,can improve nursing quality and promote patient′s recovery.
2016 Vol. 23 (2): 176-178 [Abstract] ( 104 ) HTML (45 KB)  PDF  (0 KB)  ( 30 )
179 Application of quality control in nursing document writing
ZHANG Xue-fen;JIA Zhong-ping;WU Liang
Objective To explore the impact of quality control（QC）in nursing document writing,and to enhance the quality of nursing document writing. Methods QC term was established,and the questions in nursing document writing were conducted causal factor analysis,meanwhile the improvement measures were established and practiced.200 running records,100 nursing records and 50 shift reports from before the QC activity（before June 2014）to after QC activity（after January 2015）were randomly sampling and retrospectively analyzed.The quality of nursing document writing was compared before and after the QC activity. Results After QC activity,defect rate of nursing document writing（including temperature sheet,doctors′orders,nursing records and shift reports）was lower than that of the before QC activity（P＜0.05）.The quality of nursing documents writing score from 90 points before QC activity to 98 points after QC activity. Conclusion QC can effectively improve the quality of nursing documents writing,and is worthy of clinical promotion.
2016 Vol. 23 (2): 179-181 [Abstract] ( 117 ) HTML (45 KB)  PDF  (0 KB)  ( 35 )
182 Application effect of evidence-based - humanized new nursing model in patients with hypertensive cerebral infarction
ZOU Hong-wei
Objective To explore the application effect of evidence-based - humanized new nursing model in patients with hypertensive cerebral infarction. Methods 100 patients with hypertensive cerebral infarction in our hospital from January 2013 to June 2015 were selected.Patients were divided into observation group and control group by random number table,and each group had 50 cases.Observation group was conducted with evidence-based - human nursing, control group was conducted with routine nursing.Two groups were followed up for 1 month,and the activities of daily living and action capacity,sequela situation,total hospital stay,blood pressure control when discharged and nursing satisfaction in two groups were compared. Results After intervention,the activities of daily living and action capacity in two groups was better than before intervention（P＜0.05）,and the activities of daily living and action capacity in observation group was higher better the control group（P＜0.05）.Followed-up for 1 month after discharge,the ratio of aphasia, dysarthria and limb movement disturbance in observation group were lower than those of control group（P＜0.05）.The total hospital stay in observation group was shorter than the control group（P＜0.05）,the mean arterial pressure in observation group was lower than the control group（P＜0.05）,and nursing satisfaction in observation group was higher than the control group（P＜0.05）. Conclusion Evidence-based-humanized new nursing model can obvious shorter hospital stay in patients with hypertensive cerebral infarction,improve patients′prognosis and enhance nursing satisfaction.
2016 Vol. 23 (2): 182-184 [Abstract] ( 121 ) HTML (43 KB)  PDF  (0 KB)  ( 31 )
185 Effect analysis of high quality nursing intervention in the perioperative period of laparoscopic uterine fibroids removal
LIU Lin-lin
Objective To explore the clinical nursing countermeasure of the perioperative period of laparoscopic uterine fibroids removal. Methods 50 patients with laparoscopic uterine fibroids removal admitted into our hospital from January 2012 to June 2014 were selected as study object.Patients were divided into control group and observation group according to the random number table method,with 25 cases in each group.The control group was treated with clinical routine nursing countermeasure,and the observation group was treated with high quality nursing intervention on the basis of control group.The intraoperative blood loss,hospital stay,operation time,incidence of postoperative complications, total effective rate,anxiety score and nursing satisfaction in two groups was compared. Results The indicators of intraoperative blood loss,hospital stay,operation time,incidence of postoperative complications,total effective rate,anxiety score and nursing satisfaction in observation group were better than those of control group,the differences between two groups were significant（P＜0.05）. Conclusion Apart from basis nursing for perioperative laparoscopic uterine fibroids removal patients,nurses should also pay attention to high quality nursing intervention such as psychological counseling, health education,diet nursing,pain nursing and discharge instruction.Which is helpful to enhance the therapy effect and nursing satisfaction,and promote the rehabilitation of patients.
2016 Vol. 23 (2): 185-187 [Abstract] ( 115 ) HTML (42 KB)  PDF  (0 KB)  ( 25 )
188 Influence of family-centered nursing intervention on radiotherapy compliance in patients with breast cancer
ZHANG Yan
Objective To explore the influence of family-centered nursing intervention on radiotherapy compliance in patients with breast cancer. Methods 80 patients with breast cancer performed with three-dimensional conformal or intensity modulated radiation therapy in our department from June 2012 to June 2013 were selected as research objects. They were randomly divided into intervention group and control group,with 40 cases in each group.In the control group, conventional nursing intervention was provided,while in the intervention group,family-centered nursing intervention was applied.The difference of treatment compliance in the two groups was compared. Results The level of understanding health education content in intervention group was higher than that of control group,the degree of acute radioactive damage in skin was lower than that of control group,and treatment compliance was higher than that of control group,the differences between two groups were significant（P＜0.05）. Conclusion Family-centered nursing intervention can effectively improve the radiotherapy compliance in patients with breast cancer,alleviate negative emotions,decrease radiation reaction,and improve the quality of life.
2016 Vol. 23 (2): 188-190转194 [Abstract] ( 120 ) HTML (47 KB)  PDF  (0 KB)  ( 29 )
191 Application effect of fast-track nursing under the health care integration model for interventional therapy with acute myocardial infarction
MA Shi-hong
Objective To investigate the application effect of fast-track nursing under the health care integration model for interventional therapy with acute myocardial infarction. Methods 19 cases of medical staff who work more than two years in our hospital from January 2011 to January 2014 were selected.At the same period,80 patients with acute myocardial infarction treated by interventional therapy were selected and randomly divided into observation group and control group,each group had 40 cases.The observation group was implemented with fast-track nursing under the health care integration model,the control group was implemented with routine care.The nursing work environment evaluation scores in two groups was compared,and recovery index and nursing satisfaction was computed. Results The score of doctor-nurse relation,scheduling satisfaction,nursing administrators ability and nurses actively involved in the observation group was higher than that of control group（P＜0.05）.Total hospitalization time in the observation group was shorter than the control group,getting out of bed time was earlier than the control group,the survival rate was higher than the control group,the differences between two groups were significant（P＜0.05）.The satisfaction in observation group was 95.0％,which was higher than 37.5％of control group（P＜0.05）. Conclusion The fast-track nursing under the health care integration model can significantly increase the efficiency and enthusiasm of nurses,can improve the implementation effect of interventional therapy for acute myocardial infarction,and it can increase patient satisfaction.
2016 Vol. 23 (2): 191-194 [Abstract] ( 122 ) HTML (48 KB)  PDF  (0 KB)  ( 32 )
195 Application effect of overall nursing in patients with nasal area′s hemangioma of microwave technique
HUANG Xiu-chun
Objective To investigate the application effect of overall nursing in patients with nasal area′s hemangioma of microwave technique. Methods 96 patients with nasal area′s hemangioma admitted into otolaryngology department of our hospital from March 2013 to June 2014 were seleted.According to the random number table method,they divided into care group and control group,each group had 48 cases.Two groups were treated with microwave technique,and the care group was received holistic nursing,the control group was received clinical routine care.Treatment effect and satisfaction in two groups was compared. Results Comparison with two groups of treatment effect,satisfaction and postoperative nasal mucosa recovery,and the care group was better than the control group,the differences between two groups were statistically significant（P＜0.05）. Conclusion The application effect of overall nursing in endoscopic microwave therapy nasal area′s hemangioma is good,and can effectively improve the quality of medical treatment.It is popular among patients,and is worth clinical application.
2016 Vol. 23 (2): 195-197 [Abstract] ( 122 ) HTML (47 KB)  PDF  (0 KB)  ( 25 )
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