新发2型糖尿病患者血清C肽与动脉粥样硬化的相关性研究

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Abstract Objective To explore the risk factor of atherosclerosis in patients with new-onset type 2 diabetes mellitus, and analyze the correlation and significance between serum C-peptide and atherosclerosis. Methods From November 2013 to November 2014,73 patients with new-onset type 2 diabetes mellitus visited our hospital for treatment were selected.According to whether there was atherosclerosis or not,they were divided into combination of atherosclerosis group （n＝31）and simple type 2 diabetes mellitus group（n＝42）.30 healthy people after physical examination were selected into healthy control group.The level of serum C-peptide in three groups were tested and the correlation between serum C-peptide and atherosclerosis was analyzed. Results The serum C-peptide level in simple type 2 diabetes mellitus group was obviously higher than that of healthy control group and combination of atherosclerosis group,and there was a statistical difference（P＜0.05）.There was a statistical difference of serum C-peptide level between combination of atherosclerosis group and healthy control group（P＞0.05）.There was a negative correlation between serum C-peptide level and degree of atherosclerosis（r＝-0.328,P＜0.05）.Decrease of serum C-peptide level was an independent risk factor in patients with new-onset type 2 diabetes mellitus complicated with atherosclerosis（P＜0.05）. Conclusion The level of serum C -peptide in patients with new -onset type 2 diabetes mellitus is closely related with complications of atherosclerosis,and decrease of serum C-peptide level may cause easily complication such as atherosclerosis and other vascular complication in patients with type 2 diabetes.

Key words： New-onset type 2 diabetes mellitus Serum C-peptide Atherosclerosis Correlation research

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	WANG Li

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WANG Li. Correlation research on serum C-peptide and atherosclerosis in patients with new-onset type 2 diabetes mellitus[J]. 中国当代医药, 2016, 23(2): 36-38.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I2/36

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