右美托咪定喷鼻用于急诊小儿清创缝合的效果观察

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Abstract Objective To observe the effect of intranasal dexmedetomidine used for children undergoing debridement suture surgery in department of emergency. Methods Forty children undergoing debridement suture surgery in department of emergency of our hospital from January 2014 to March 2015 were selected,and were randomly divided into two groups,20 cases in each group.The children in group A were treated with 10％chloral hydrate as enema（0.5 ml/kg）, while the group B were treated with intranasal dexmedetomidine（2 μg/kg）,debridement suture surgery undergoing with 2％lidocaine after sedation.Heart rates,respiratory rates and oxyhemoglobin saturations before and after treatment between two groups were monitored and compared.The sedative effect between two groups was observed.Ramsay scores was obtained.The times to calm down and to wake up and the adverse reactions were recorded. Results The debridement suture surgery was completed between two groups after treatment.The sedative effect of group B was better than that of group A.The waking up time in group B was shorter than that of group A.No adverse reaction occured in group B,one child was found with nausea and vomiting in group A. Conclusion Intranasal dexmedetomidine used for children undergoing debridement suture surgery in department emergency has the advantages of taking action and recovery fast, good sedative effect and less incidence of adverse reactions than that with chloral hydrate,which is worth clinical popularizing and applying.

Key words： Dexmedetomidine Department of emergency Child Sedation Debridement suture surgery

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	Articles by authors
	SHI Bao-zhu
	SHI Xiu-xia
	YANG Ming-hua
	XU Zai-chao
	JI Shi-qiang

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SHI Bao-zhu,SHI Xiu-xia,YANG Ming-hua, et al. Observation on the sedative effect of intranasal dexmedetomidine used for children undergoing debridement suture surgery in department of emergency[J]. 中国当代医药, 2016, 23(2): 103-105.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I2/103

[1]	侯春林.水合氯醛灌肠应用与婴幼儿清创缝合的效果[J].中国医学工程，2011，19（2）：103.
[2]	李记森，王智亮，王少华，等.水合氯醛灌肠在儿科门诊手术及治疗中的作用[J].中国实用医药杂志，2008，3（7）：99-100.
[3]	金立红，许文妍，白洁，等.水合氯醛用于小儿影像学检查时镇静的有效性和安全性[J].临床麻醉学杂志，2013， 29（7）：678-680.
[4]	戈明媚，刘志钦，王秋良，等.婴幼儿磁共振检查镇静剂首次应用失败原因分析[J].医疗卫生装备杂志，2010，31 （4）：273-274.
[5]	唐丽君.婴幼儿检查前应用10％水合氯醛保留灌肠催眠效果[J].吉林医学，2007，28（6）：758.
[6]	芦映红.水合氯醛不良反应的防治[J].医药导报，2011，30 （1）：127-128.
[7]	李永强.右美托咪定小儿麻醉的应用分析[J].中国医药指南，2014，12（8）：120-121.
[8]	龚琴，彭健泓，陈立成，等.右美托咪定连续静脉输注用于小儿CT检查期间的镇静效果观察[J].医学临床研究，2013，30（7）：1284-1286.
[9]	郭莲，徐国海.右美托咪定在小儿患者的临床应用进展[J].国际麻醉学与复苏杂志，2012，33（6）：408-411.
[10]	李碧莲，宋兴荣，李玉琼，等.鼻内给予右美托咪定与口服水合氯醛在患儿CT检查中的有效性和安全性[J].临床麻醉学杂志，2013，29（9）：859-862.
[11]	贾继娥，陈佳瑶.白内障手术患儿右美托嘧定术前滴鼻的镇静效果[J].临床麻醉学杂志，2012，28（12）：1172-1174.
[12]	Vilo S，Rautiainen P，Kaisti K，et al.Pharmacokinetics of intravenous dexmedetomidine in children under 11 years of age[J].Br J Anaesth，2008，100（5）：697-700.
[13]	齐爽，李云龙，梁枫.右美托嘧定喷鼻用于小儿核磁共振检查镇静效果的观察[J].中国妇幼保健杂志，2014，29（23）：3832-3833.
[14]	Yuen VM，Hui TW，Irwin MG，et al.A randomised comparision of two intranasal dexmedetomidine doses for premedication in children[J].Anaesthesia，2012，67（11）：1210-1216.
[15]	Yuen VM，Hui TW，Irwin MG，et al.Optimal timing for the administration of intranasal dexmedetomidine for the premedication in children[J].Anaesthesia，2010，65（9）：922-929.