Home                              中文

Forthcoming Articles Current Issue Archive Advanced Search Read Articles Download Articles Email Alert

Quick Search     Adv Search 2022 Vol. 29, No. 10 Published: 2022-04-08   5 Effect of minimum dose of Esketamine combined with Dexmedetomidine on resuscitation and sore throat after general anesthesia JIN Yongqiang ;ZHANG Nini ;ZHOU Wenfeng ;ZHANG Lei ;GUO Lin ;TANG Jing Objective To explore the effect of minimum dose of Esketamine combined with Dexmedetomidine on resuscitation and sore throat after general anesthesia.Methods A total of 90 patients who underwent elective endotracheal intubation in the Department of Anesthesiology,the Fifth Affiliated Hospital of Guangzhou Medical University from October 2020 to June 2021 were selected as the research subjects,and were divided into control group(n=45)and observation group(n=45)according to random number table method.The control group was continuously pumped with Remifentanil and Dexmedetomidine,while the observation group was continuously pumped with the lowest dose of Esketamine and Dexmedetomidine.The recovery time and extubation time were compared between the two groups.The changes of circulatory indexes in two groups were observed before administration(T0),at extubation(T1),and at 0.5 h(T2)and 1 h(T3)after administration.Ricker sedative-agitation score(SAS)was compared between the two groups after awakening.The related complications in the resuscitation period of patients in the two groups were analyzed.The visual analogue scale(VAS)score of wound at exit,6 h after surgery and the VAS score of sore throat at 12 h after surgery were evaluated.Results There were no significant differences in the recovery time and extubation time between two groups(P＞0.05).The HR of observation group at T2 and T3 were higher than those of control group,the differences were statistically significant(P＜0.05).There was no significant difference in MAP between the two groups at each time point(P＞0.05).There was no significant difference in SAS score between two groups after awakening(P＞0.05).There were no drug-related complications in the recovery period in both groups.There was no significant difference in VAS score between the two groups at exit and 6 h after surgery(P＞0.05).While the sore throat VAS score at 12 h after operation in the observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion The minimal dose Esketamine and Dexmedetomidine intravenous injection does not affect the recovery time and extubation time of patients,and stabilizes the cardiovascular system.There are no psychotic side effects.It can also effectively inhibit postoperative wound pain and sore throat.In the recovery period of anesthesia,the administration scheme can be used as an alternative to opiates,which is worth clinical reference. 2022 Vol. 29 (10): 5-09 [Abstract] ( 43 ) HTML (1 KB)  PDF (611 KB)  ( 235 ) 10 Effect of Cyclophosphamide combined with Leflunomide on 24 h urine protein and serum β2 microglobulin levels in patients with lupus nephritis GUAN Yibiao; LUO Fuzhang; LI Yanhua Objective To investigate the effect of Cyclophosphamide combined with Leflunomide on 24 h urine protein and serum β2 microglobulin levels in patients with lupus nephritis.Methods A total of 68 patients with lupus nephritis who were admitted to Nanhai District People's Hospital in Foshan City from August 2018 to August 2020 were selected as the research objects,and they were divided into single group(n=34)and combined group(n=34)by random envelope grouping method.The single group was treated with intravenous Cyclophosphamide,and the combined group was treated with Leflunomide orally on the basis of intravenous Cyclophosphamide.The 24 h urine protein and serum β2 microglobulin levels were compared between the two groups before and after treatment.The changes of liver and kidney function indexes were compared between the two groups before and after treatment.The differences of total effective rate and incidence of adverse reactions between the two groups were analyzed.Results Before treatment,there were no significant differences in the 24 h urine protein level and serum β2 microglobulin level between the two groups(P＞0.05).After treatment,the 24 h urinary protein level and serum β2 microglobulin level in combined group were lower than those in single group,the differences were statistically significant(P＜0.05).Before treatment,there were no statistical significances in serum urea nitrogen,serum creatinine,aspartate aminotransferase and alanine aminotransferase levels between the two groups(P＞0.05).After treatment,the levels of serum urea nitrogen,serum creatinine,aspartate aminotransferase and alanine aminotransferase in combined group were lower than those in single group,the differences were statistically significant(P＜0.05).The total effective rate of combined group was higher than that of single group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions in combined group was lower than that in single group,and the difference was statistically significant(P＜0.05).Conclusion The combined treatment of Cyclophosphamide and Leflunomide in patients with lupus nephritis can effectively improve 24 h urine protein and serum β2 microglobulin levels,and at the same time improve various indexes of liver and kidney function,which contributes to the overall effective rate of clinical treatment promote.In addition,the adverse reactions are small,the safety is high,and it has certain clinical promotion and application value. 2022 Vol. 29 (10): 10-13转19 [Abstract] ( 40 ) HTML (1 KB)  PDF (605 KB)  ( 47 ) 14 Application effect of 4∶1 blood cardioplegia and histidine-tryptophan-ketoglutarate solution in cardiac valve replacement GONG Jianping ;LIANG Xiusheng; LI Weichao ;LIU Yuyan; LENG Binghua ;CHEN Guomin ;LI Heng Objective To investigate the application effect of 4∶1 blood cardioplegic fluid and domestic histidine -tryptophan-ketoglutaric acid(HTK)in cardiac valve replacement.Methods A retrospective analysis was performed on the clinical data of 64 patients undergoing cardiac valve replacement under extracorporeal circulation in Qingyuan People's Hospital from February 2018 to December 2020.The patients were divided into group H and group G according to the different use of myocardial protective fluid during cardiopulmonary bypass aorta occlusion,with 32 cases in each group.Patients in group H were treated with a single infusion of domestic HTK liquid as myocardial protective fluid to induce cardiac arrest,and patients in group G were treated with multiple perfusion of 4∶1 blood cardioplegia fluid.Blood gas indexes,electrolyte concentration,mean arterial pressure(MAP)and perioperative indexes before transfer after induction of anesthesia(T1),10 min after transfer(T2),10 min after aorta blocking infusion of stopper fluid(T3),5 min after cardiopulmonary bypass rewarming(T4),10 min after aortic opening at min(T5)and after shutdown(T6)were compared between the two groups of patients.Results There were no significant differences in blood gas pH value between the two groups at different time(P＞0.05).|BE| value of group H at T3,T4 and T5 moment were higher than those of the group G,the differences were statistically significant(P＜0.05).Lac in group H at T3 was lower than that in group G,Lac at T4 and T5 were higher than those in group G,the differences were statistically significant(P＜0.05).Carbon dioxide partial pressure(PaCO2)at T5 in group H was higher than that in group G,the difference was statistically significant(P＜0.05).Electrolyte K+concentration at T4 in group H was lower than that in group G,the difference was statistically significant(P＜0.05).The HCT value of group H at T3 and T4 were lower than those of group G,and the differences were statistically significant(P＜0.05).The MAP of group H at T5 was lower than that of group G,the difference was statistically significant(P＜0.05).In group H,PaCO2,HCT and MAP values at T2,T3,T4,T5 and T6 were lower than those at T1,Lac values at T4,T5 and T6 were higher than those at T1,and K+ concentrations at T3,T4,T5 and T6 were higher than those at T1,the differences were statistically significant(P＜0.05).PaCO2 and HCT values of patients at T2,T3,T4,T5 and T6 in group G were lower than T1,K+concentration at T3,T4,T5 and T6 were higher than T1,MAP value at T2,T3,T5 and T6 were lower than T1,Lac value at T4,T5 and T6 were higher than T1,the differences were statistically significant(P＜0.05).There were no significant differences in operation time,ICU stay time and incidence of postoperative complications between the two groups(P＞0.05).The time of cardiopulmonary bypass in group H was shorter than that in group G,and the amount of cardiopulmonary bypass was lower than that in group G,the differences were statistically significant(P＜0.05).Conclusion The use of 4∶1 blood containing cardiopulmonary bypass solution and home-made HTK fluid during valve replacement with cardiopulmonary bypass has less influence on the internal environment of patients. 2022 Vol. 29 (10): 14-19 [Abstract] ( 44 ) HTML (1 KB)  PDF (643 KB)  ( 161 ) 20 Curative effect of Reduced Glutathione in different stages of chronic renal failure PENG Ting; PENG Weihua;XU Minmin; WEI Lifang Objective To explore the application effect of Reduced Glutathione in patients with chronic renal failure.Methods A total of 260 patients with chronic renal failure admitted to the Third People's Hospital of Fujian University of Traditional Chinese Medicine from January 2018 to January 2021 were selected as the research objects,and were divided into observation group(130 cases)and control group(130 cases)using the random number table method.The observation group was treated with conservative treatment combined with Reduced Glutathione,and the control group was treated with conservative treatment.The hemoglobin(Hb)and serum creatinine(Scr)levels of the two groups were compared.Results Before treatment,the Hb and Scr levels of the two groups were not statistically different(P＞0.05).After treatment,the Hb level of the observation group was higher than that of the control group,and the Scr level was lower than that of the control group,the differences were statistically significant(P＜0.05).After treatment,Hb level of patients with chronic kidney disease(CKD)stage 3,CKD stage 4 and CKD stage 5 in the observation group was higher than that in the control group,while Scr level was lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Reduced Glutathione has a positive effect in the treatment of patients with chronic renal failure,it can effectively improve the renal function of patients,and is suitable for patients in different stages of disease progression such as CKD3,CKD4,and CKD5.It is worthy of promotion. 2022 Vol. 29 (10): 20-23 [Abstract] ( 51 ) HTML (1 KB)  PDF (567 KB)  ( 181 ) 24 Establishment and validation of urinary tract infection score prediction model caused by gram-positive or negative bacteria YANG Kaihong ;ZENG Qingzhan; FENG Bin Objective To establishment and validation of urinary tract infection(UTI)score prediction model caused by gram-positive(G+)or gram-negative bacteria(G-),and verify the prediction efficiency of the scoring model.Methods A total of 182 patients with UTI treated in Yangjiang Hospital of Traditional Chinese Medicine,Guangdong Province from January 2019 to May 2021 were retrospectively analyzed.According to random number table method,they were divided into modeling group(91 cases,59 cases of G- bacteria,G+ bacteria 32 cases)and verification group(91 cases,59 cases of G-bacteria,G+bacteria 32 cases).The risk prediction model of G+bacteria infection was constructed by binary logistic regression analysis to screen the relevant influencing factors,and the prediction ability of the model was judged.Results A total of 225 strains were detected,including 138 G- strains,75 G+ strains and 12 fungi.The AUC of G- bacterial infection predicted by bacterial count in the modeling group was 0.793,and the best cut-off value was 320/μl.The AUC of G-bacterial infection predicted by white blood cell(WBC)count was 0.699,and the best cut-off value was 64/μl.Binary logistic regression analysis showed that nitrite(NIT)negative,urinary sediment stained G+bacteria,bacterial count ＜320.00/μl and WBC count ＜64/μl were the influencing factors of G+ bacteria in UTI patients,and 11,4,5 and 4 points were assigned respectively.The AUC of model subjects in the modeling group was 0.874 and that in the validation group was 0.877.The risk of G+bacteria infection was stratified,0-11 points was divided into low G+bacteria risk,13-19 points was medium G+ bacteria risk,and 20-24 points was high G+ bacteria risk.Conclusion The score prediction model has good discrimination and calibration,which is convenient for the prediction of pathogens and clinical medication according to the model. 2022 Vol. 29 (10): 24-28 [Abstract] ( 39 ) HTML (1 KB)  PDF (667 KB)  ( 173 ) 29 Research progress of Chinese medicine combined with tumor-targeted drugs in the treatment of non-small cell lung cancer WEN Li ;WANG Li In recent years,the incidence and mortality of lung cancer have risen sharply,ranking first among cities.The treatment of lung cancer needs to adopt a multi-disciplinary comprehensive treatment model based on the patient's physical condition,cytology,tumor,pathological type,etc.,and focus on individualized treatment.Non-small cell lung cancer is the most common type of lung cancer,and it is also one of the diseases with high mortality of lung cancer,Targeted therapy is the preferred treatment option for non-small cell lung cancer.With the expansion of the use of targeted drugs,the emergence of drug resistance and adverse reactions slowed the treatment process.At present,Chinese medicine combined with tumor-targeted drugs in the treatment of non-small cell lung cancer has become a research hotspot.Relevant studies have shown that Chinese medicine combined with tumor-targeted drugs can improve survival rate and quality of life,reduce adverse reactions and delay the time for patients to develop drug resistance.This article will further summarize the research of Chinese medicine combined with tumor-targeted drug therapy in the field of non-small cell lung cancer,in order to provide a theoretical basis for Chinese medicine combined with tumor-targeted drug therapy,and provide a theoretical basis for prevention of drug resistance and clinical treatment. 2022 Vol. 29 (10): 29-33 [Abstract] ( 44 ) HTML (1 KB)  PDF (483 KB)  ( 360 ) 34 Research progress of Chinese medicine in treating diabetic foot LIU Tingyu;LI Dayong Diabetic foot(DF)is one of the common chronic complications of diabetes,that is characterized by complex condition,long course of disease,high recurrence rate,high mortality rate and high treatment cost.In the face of the poor clinical efficacy of western medicine treatment,while traditional Chinese medicine treatment has the advantages of wide audience and significant efficacy,actively explore the role of traditional Chinese medicine in the treatment of diabetic foot,in order to reduce the incidence,recurrence rate and mortality of DF. 2022 Vol. 29 (10): 34-37转41 [Abstract] ( 48 ) HTML (1 KB)  PDF (856 KB)  ( 383 ) 38 Study on immune status of patients with serum fixation of early syphilis based on changes of interleukin-2 and interleukin-10 LI Qingxiang ;ZENG Mei Objective To study the changes of interleukin-2(IL-2)and interleukin-10(IL-10)in patients with serum fixation of early syphilis,and to explore the immune status of patients.Methods From January 2017 to January 2019,30 patients with serum fixation of early syphilis in the Department of Dermatology of Huizhou Central People's Hospital were selected as the observation group.Another 30 patients with the negative serological test for syphilis(TURST)after standardized antisyphilitic treatment were the negative conversion group.Another 30 healthy subjects were selected as the control group.The levels of IL-2 and IL-10 in the three groups were compared.Results The IL-2 level in observation group was lower than that in the negative conversion group and control group,and the IL-10 level was higher than that in the negative conversion group and control group,and the differences were statistically significant(P＜0.05).There were no significant differences in IL-2 and IL-10 levels between the negative group and the control group(P＞0.05).Conclusion Patients with serum fixation of early syphilis have some immunosuppression and immune imbalance.In clinical treatment of syphilis,in addition to antibiotics,personalized immune intervention measures should be combined. 2022 Vol. 29 (10): 38-41 [Abstract] ( 35 ) HTML (1 KB)  PDF (599 KB)  ( 79 ) 42 Study on smart phone application assisted bronchial asthma health management SUN Junsheng; YAO Dingye;HUANG Xianghui;MAI Guishan;LI Yushao Objective To assess the impact of health management assisted by smart phone application on bronchial asthma control and quality of life.Methods A total of 92 patients with stable bronchial asthma who visited the Outpatient Department of Longgang Central Hospital of Shenzhen from May to October 2020 were selected as the research subjects and divided into conventional management group(46 cases)and smart phone application group(46 cases)according to the random number table method.The conventional management group was given Budesonide Formoterol Powder Inhaler,precautions were informed,and follow-up was emphasized(1,3 and 6 months after treatment).On the basis of the conventional management group,the smart phone application group performed asthma management and follow-up assisted by smart phone applications.Patients established direct contact with the doctor's smart phone app through wechat,and the app regularly sent messages to remind patients to return visit and push popular science knowledge.Asthma control test(ACT),Leicester cough questionnaire(LCQ),asthma quality of life questionnaire(AQLQ),peak expiratory flow variability(PEFV),emergency department visits and unplanned hospitalizations during follow-up were compared between the two groups.Results ACT,LCQ and AQLQ scores of the smart phone application group were higher than those of the conventional management group after intervention,the differences were statistically significant(P＜0.05).The PEFV of the smart phone application group was lower than that of the conventional management group after intervention,the difference was statistically significant(P＜0.05).There was no significant difference in the number of emergency visits and inpatients between the two groups(P＞0.05).Conclusion Implementing health management assisted smart phone app can reduce clinical symptoms,improve the control rate of bronchial asthma and improve the quality of life. 2022 Vol. 29 (10): 42-45 [Abstract] ( 43 ) HTML (1 KB)  PDF (561 KB)  ( 66 ) 46 Clinical effect of short-term glucocorticoids combined with nucleoside analogues in the treatment of patients with severe hepatitis PENG Fang ;TU Long ;LIAO Qun Objective To investigate the clinical effect of short-term glucocorticoid(GC)combined with nucleoside analogues in the treatment of patients with severe hepatitis.Methods The clinical data of 60 patients with severe hepatitis who were admitted to the Second Affiliated Hospital of Yichun University from January 2013 to December 2020 were retrospectively analyzed.According to different drug treatment methods,they were divided into experimental group(29 cases)and control group(31 cases).The control group was treated with antiviral nucleoside analogues and conventional medical treatment,and the experimental group was treated with GC for 5-7 days.The clinical efficacy,liver function,coagulation function and the occurrence of adverse reactions were compared between the two groups.Results There was no significant difference in clinical treatment effect between the two groups(P＞0.05).The levels of total bilirubin(TBil)and alanine aminotransferase(ALT)in experimental group were lower than those in control group,the differences were statistically significant(P＜0.05).There was no significant difference in albumin(ALB)between the two groups after treatment(P＞0.05).After treatment,prothrombin time(PT)and activated partial thrombin time(APTT)in experimental group were shorter than those in control group,while fibrinogen(FIB)and prothrombin activity(PTA)in experimental group were lower than those in control group,the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Compared with nucleoside analogues alone,curative effect of short-term GC combined with nucleoside analogues is more significant on patients with early severe hepatitis,which can effectively improve liver function and coagulation dysfunction,with good safety. 2022 Vol. 29 (10): 46-49 [Abstract] ( 38 ) HTML (1 KB)  PDF (586 KB)  ( 27 ) 50 Effect of taking Simethicone at different time points before colonoscopy on intestinal cleanliness and polyp detection rate ZHAI Chunying; KE Xiaoli ;XU Yaohua ;CHENG Xiaohe ;QIU Yu Objective To study the effect of taking Simethicone at different time points before colonoscopy on intestinal cleanliness and the detection rate of intestinal polyps.Methods The 200 patients who underwent colonoscopy in Beijing Puren Hospital from January 2020 to June were selected s vesearch objects,they were divided into group A,group B and group C according to the random number table method.Group A(n=70)took Simethicone 2 h before the colonoscopy,group B(n=65)took simethicone 1 h before the examination,and group C(n=65)took Simethicone 0.5 h before the examination.The differences in intestinal cleanliness,intestinal polyp detection rate and intestinal air bubbles before examination were compared among the three groups of patients.Results There was no statistically significant difference in the score of intestinal cleanliness of the three groups of patients(P＞0.05).The comparison of the detection rate of intestinal polyps ＞0.5 cm and the total detection rate of intestinal polyps in the three groups of patients were not statistically significant(P＞0.05).The detection rate of intestinal polyps ≤0.5 cm in group B was higher than that in group A and group C,the difference was statistically significant(P＜0.05).The score of intestinal air bubbles in group B was higher than that in group A and group C,and the difference was statistically significant(P＜0.05).Conclusion Taking Simethicone at different time points before colonoscopy has no effect on intestinal cleansing,but taking Simethicone 1 h before the examination can increase the detection rate of small polyps and more effectively inhibit the production of intestinal bubbles,which has positive value. 2022 Vol. 29 (10): 50-52转56 [Abstract] ( 38 ) HTML (1 KB)  PDF (567 KB)  ( 79 ) 53 Effect of intermediate frequency electrotherapy combined with extracorporeal shock wave in the treatment of patients with neck,shoulder,waist and leg pain TAI Jie ;KONG Weikuan ;LIU Jun'e ;ZHENG Ying Objective To study the application effect of intermediate frequency electric therapy combined with extracorporeal shock wave in the treatment of patients with neck,shoulder,waist and leg pain.Methods A total of 86 patients with neck,shoulder,waist and leg pain admitted to Liaocheng Second People's Hospital from May 2019 to May 2021 were selected as research objects.They were divided into observation group and control group according to coin toss method,with 43 cases in each group.The control group received conventional rehabilitation therapy,and the observation group received intermediate frequency electric therapy combined with extracorporeal shock wave therapy on the basis of the control group.Both groups were treated for 28 d.After 28 d of treatment,compare the clinical effects of the two groups,compare the pain levels(visual analogue scale[VAS])and total patient satisfaction before and after 28 d of treatment between the two groups.Results The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).After 28 d of treatment,the VAS scores of the two groups were lower than those before treatment,and the score of the observation group was lower than that of the control group,the differences were statistically significant(P＜0.05).After treatment,the total satisfaction degree of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Intermediate frequency electrotherapy combined with extracorporeal shock wave applied in the treatment of patients with neck,shoulder,waist and leg pain can improve the curative effect,further reduce the pain of the patients,and improve the satisfaction of the patients. 2022 Vol. 29 (10): 53-56 [Abstract] ( 45 ) HTML (1 KB)  PDF (557 KB)  ( 206 ) 57 Effect of Dapagliflozin on cardiac function，inflammatory response and cardiovascular outcomes in patients with unstable angina pectoris and type 2 diabetes after percutaneous coronary intervention ZHANG Gang Objective To explore the effect of Dapagliflozin on cardiac function,inflammatory response and cardiovascular outcome in patients with unstable angina(UA)combined with type 2 diabetes(T2DM)after percutaneous coronary intervention(PCI).Methods A total of 70 patients with UA combined with T2DM who underwent PCI in Liaoyang Central Hospital from September 2018 to September 2019 were selected as the research subjects,and they were divided into an observation group and a control group by random number table method,each with 35 cases.Both groups of patients were treated with conventional drugs.On this basis,patients in the observation group were treated with Dapagliflozin to control blood sugar and patients in the control group were treated with hypoglycemic drugs other than sodium-glucose cotransporter 2(SGLT-2)inhibitor.Both groups were treated continuously for 24 weeks.The differences in left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD),left ventricular ejection fraction(LVEF),inflammatory factor levels before and after treatment and major adverse cardiovascular events(MACE)between the two groups were analyzed.Results After treatment,LVEF of observation group was higher than that of control group,LVESD and LVEDD of observation group were lower than those of control group,the differences were statistically significant(P＜0.05).After treatment,the levels of C-reactive protein(CRP),interleukin 6(IL-6),tumor necrosis factor-α(TNF-α)of observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).During the treatment period,there were no significant differences in the incidence rates of cardiogenic death,recurrent myocardial infarction and other adverse cardiovascular events between the two groups of patients(P＞0.05),but the incidence rates of severe arrhythmia and heart failure in the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion Dapagliflozin treatment for patients with UA combined with T2DM after PCI can improve heart function to a certain extent,reduce the levels of inflammatory factors as well as the incidence of MACE. 2022 Vol. 29 (10): 57-61 [Abstract] ( 46 ) HTML (1 KB)  PDF (503 KB)  ( 108 ) 62 Effect of ST segment changes in lead aVR of patients with non-ST- segment elevation acute coronary syndrome QIN Yuansheng;TANG Xiu'e Objective To discuss the effect of ST segment changes in lead aVR of patients with non-ST-segment elevation acute coronary syndrome(NSTE-ACS).Methods A total of 168 patients with NSTE-ACS in the First Affiliated Hospital of Dalian Medical University from July 2019 to July 2020 were analyzed retrospectively,and divided into the non STaVR segment elevation group(65 cases),STaVR segment elevation 0.05-0.1 mV group(58 cases)and STaVR segment elevation ≥0.1 mV group(45 cases)according to the ST segment degree of improvement in lead aVR measurements at admission.The baseline data,occurrence of MACE within 6 months of three groups of patients were recorded and analyzed.Results The history of myocardial infarction,left ventricular ejection fraction(LVEF),Killip grade,number of diseased vessels and treatment regimen of the three groups were significant differences(P＜0.05).The cTnI,CK-MB,BNP and hs-CRP levels of the three groups were significant differences(P＜0.05);The cTnI,CK-MB,BNP and hs-CRP levels of STaVR segment elevation ≥0.1 mV group and STaVR segment elevation 0.05-0.1 mV group were higher than those of the non STaVR segment elevation group,the STaVR segment elevation ≥0.1 mV group were higher than the STaVR segment elevation 0.05-0.1 mV group,and the differences were statistically significant(P＜0.05).The(repeat)myocardial infarction,cardiovascular death and revascularization incidence rates of the three groups within 6 months were significant different(P＜0.05).The(repeat)myocardial infarction,cardiovascular death and revascularization incidence rates of the STaVR segment elevation ≥0.1 mV group and the STaVR segment elevation 0.05-0.1 mV group were higher than those of the non STaVR segment elevation group,the STaVR segment elevation ≥0.1 mV group were higher than the STaVR segment elevation 0.05-0.1 mV group,the differences were statistically significant(P＜0.05).The distribution of non STaVR segment elevation,STaVR segment elevation 0.05-0.1 mV and STaVR segment elevation ≥0.1 mV of NSTE-ACS patients MACE occurrence or not within 6 months were significant differences(P＜0.05).Multivariate logistic regression analysis showed that the LVEF(β=0.288,OR=1.586,95%CI=1.267-2.831),Killip classification(β=0.271, OR=1.716,95%CI=1.359-2.498),number of vessel branches(β=0.743, OR=2.247,95%CI=1.664-3.576),cTnI(β=0.553, OR=2.093,95%CI=1.537-3.498),CK-MB(β=1.105, OR=2.358,95%CI=1.239-3.869),BNP(β=0.934, OR=1.529,95%CI=0.913-2.722),hs-CRP(β=0.326, OR=1.768,95%CI=1.175-2.246)and STaVR segment elevation(β=0.179, OR=1.452,95%CI=1.123-2.051)were independent risk factors for MACE occurs within 6 months of NSTE-ACS patients(P＜0.05).Conclusion The MACE incidence of NSTE-ACS patients with electrocardiogram STaVR segment elevation ≥0.1 mV is higher,moreover STaVR segment elevation is the independent risk factors for MACE occurs within 6 months in NSTE-ACS patients,which should be paid much attention. 2022 Vol. 29 (10): 62-66转70 [Abstract] ( 39 ) HTML (1 KB)  PDF (498 KB)  ( 58 ) 67 Effect of Amiodarone in emergency treatment of tachyarrhythmia cardioversion CHEN Miaomiao;ZHANG Jiangyi;TIAN Lihong Objective To investigate the effect of Amiodarone on the emergency treatment of tachyarrhythmia cardioversion.Methods From January 2018 to January 2020,72 patients with tachyarrhythmia admitted to the Department of Emergency Medicine of Zhongguancun Hospital in Beijing were selected as the research objects,and they were divided into control group(n=36)and observation group(n=36)using random number table method.The control group was treated with Propafenone,and the observation group was treated with Amiodarone.The total effective rate,heart rate(HR),diastolic blood pressure(DBP),systolic blood pressure(SBP),PR interval,QT interval and incidence of adverse reactions of the two groups were compared before and after treatment.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).HR,DBP and SBP of the two groups after treatment were lower than those before treatment and the indexes of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05);after treatment in the two groups were longer than before treatment,and the PR interval and QT interval in the observation group after treatment were longer than those in the control group,the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Amiodarone has a definite effect on the emergency treatment of tachyarrhythmia cardioversion,which can keep the patient's heart rate stable,with few adverse reactions and high safety. 2022 Vol. 29 (10): 67-70 [Abstract] ( 44 ) HTML (1 KB)  PDF (450 KB)  ( 48 ) 71 Clinical effect of Mirtazapine combined with Paroxetine in the treatment of depressive patients with sleep disorder LUAN Lei; WANG Yanru Objective To investigate the clinical effect of Mirtazapine combined with Paroxetine in the treatment of depressive patients with sleep disorder.Methods A total of 96 patients with depression with sleep disorder treated in Yingkou Fourth People's Hospital from January 2019 to January 2020 were selected as the research objects.They were divided into observation group(48 cases)and control group(48 cases)by random number table method.The control group was treated with Paroxetine,and the observation group was treated with Paroxetine combined with Mirtazapine.The clinical efficacy was compared between the two groups after treatment,and the scores of self-rating depression scale(SDS),Hamilton depression scale(HAMD)and Pittsburgh sleep quality index(PSQI)were compared between the two groups before and after treatment.Results The total effective rate of observation group(91.7%)was higher than that of control group(79.2%),and the difference was statistically significant(P＜0.05).After treatment,SDS score of observation group was lower than that in the control group,the difference was statistically significant(P＜0.05).HAMD score and PSQI score in the observation group were lower than those in the control group at 4 and 8 weeks after treatment,the differences were statistically significant(P＜0.05).Conclusion Mirtazapine combined with Paroxetine in the treatment of depressive patients with sleep disorder can effectively reduce depressive symptoms,improve depression mood and sleep quality,with significant clinical efficacy,worthy of clinical promotion. 2022 Vol. 29 (10): 71-74 [Abstract] ( 41 ) HTML (1 KB)  PDF (554 KB)  ( 22 ) 75 Clinical application of neurological intensive care combined with long range video electroencephalogram monitoring in patients with refractory status epilepticus ZHANG Jinshi; LI Yihua ;ZENG Hailan; LUO Fei ;TANG Zhiji ;YANG Ruijin Objective To investigate the clinical application effect of neurological intensive care combined with long range video electroencephalogram monitoring in patients with refractory status epilepticus.Methods A total of 78 patients with refractory status epilepticus who were admitted to ICU of Department of Neurosurgery,Ganzhou People's Hospital from May 2018 to May 2020 were selected as the research subjects.They were divided into the reference group(39 patients)and the study group(39 patients)by the random number table method.Patients in the reference group were treated with neurological intensive care intervention,and patients in the study group were treated with neurological intensive care combined with long range video electroencephalogram monitoring intervention.The clinical disease control effect rate,attack control time,intubation time and incidence of nervous system dysfunction were compared between the two groups.Results The effective rate of clinical disease control in the study group was higher than that in the reference group,and the difference was statistically significant(P＜0.05).The attack control time and intubation time of patients in the study group were shorter than those in the reference group,and the differences were statistically significant(P＜0.05).The incidence of neurological dysfunction in the study group was lower than that in the reference group,and the difference was statistically significant(P＜0.05).Conclusion During the treatment of patients with refractory status epilepticus,the application of neurological intensive care combined with long range video electroencephalogram monitoring has a significant effect,which can effectively control the clinical condition,shorten the attack control time and intubation time,and reduce the incidence of neurological dysfunction. 2022 Vol. 29 (10): 75-77 [Abstract] ( 34 ) HTML (1 KB)  PDF (518 KB)  ( 74 ) 78 Effect of Pregabalin + Escitalopram on pain degree and depression in patients with central neuralgia after stroke QI Qiongyao;ZENG Duo; LI Jun;ZHENG Xiaodong; YI Fei Objective To investigate the effect of Pregabalin + Escitalopram on pain degree and depression in patients with central neuralgia after stroke.Methods A total of 60 patients with central neuralgia after stroke treated in Pingxiang People's Hospital from July 2018 to July 2021 were selected as research subjects,and they were divided into control group(n=30)and observation group(n=30)by random number table method.The control group received conventional treatment,and the observation group treated with Pregabalin + Escitalopram.Visual analog scale(VAS),Hamilton depression scale(HAMD)and Hamilton anxiety scale(HAMA)scores were compared between the two groups.Results Before treatment,there were no significant differences in VAS,HAMA and HAMD scores between the two groups(P＞0.05).After treatment,VAS,HAMA and HAMD scores in the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,VAS,HAMA and HAMD scores in observation group were lower than those in control group,the differences were statistically significant(P ＜0.05).Conclusion Pregabalin + Escitalopram have positive effect on the improvement of pain symptoms and depression in patients with central neuralgia after stroke. 2022 Vol. 29 (10): 78-80转84 [Abstract] ( 37 ) HTML (1 KB)  PDF (549 KB)  ( 119 ) 81 Application effect of contralateral active control training in post-stroke pusher syndrome YANG Mengrui; QIU Zhiyong Objective To explore the application effect of contralateral active control training in post-stroke pusher syndrome(PS).Methods A total of 58 patients with stroke treated in the Department of Rehabilitation Medicine of Aviation General Hospital of China Medical University from October 2019 to August 2021 were selected as the research subjects,according to the random number table method,they were divided into the control group and the treatment group,in which 3 cases fell off in the treatment group and 3 cases fell off in the control group,26 cases in each group completed the study.The control group was treated with routine rehabilitation training,and the treatment group was treated with routine rehabilitation training combined with contralateral active control training.Both groups were treated for 6 weeks.Burke lateropulsion scale(BLS),Berg balance scale(BBS)and Trunk impairment scale(TIS)were used to evaluate the changes of balance and trunk control function in the two groups.Results The BLS scores of patients in the two groups after 6 weeks of treatment were lower than those before treatment,and the BBS and TIS scores of patients in the two groups after 6 weeks of treatment were higher than those before treatment,and the BLS of the treatment group after 6 weeks of treatment was lower than that of the control group,and the scores of BBS and TIS of the treatment group after 6 weeks of treatment were higher than that of the control group,the differences were statistically significant(P＜0.05).The scores of Trunk impairment scale static(TIS-S),Trunk impairment scale dynamic(TISD)and Trunk impairment scale coordination(TIS-C)in the two groups after 6 weeks of treatment were higher than those before treatment,and the scores of TIS-S,TIS-D and TIS-C in the treatment group after 6 weeks of treatment were higher than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Contralateral active control training can significantly improve the balance and trunk control function of PS patients after stroke,and the improvement of trunk function is more comprehensive. 2022 Vol. 29 (10): 81-84 [Abstract] ( 38 ) HTML (1 KB)  PDF (559 KB)  ( 77 ) 85 Clinical effect of ultra-early small bone window intracranial hematoma removal in the treatment of hemorrhage in basal ganglia of hypertension CHEN Xiya Objective To investigate the clinical effect of ultra-early small bone window intracranial hematoma removal in the treatment of hemorrhage in the basal ganglia of hypertension.Methods A total of 81 patients with hemorrhage in the basal ganglia of hypertension admitted to Wuhan Xinzhou District People's Hospital from January 2019 to January 2021 were selected as the research objects,they was divided into the observation group(41 cases)and the control group(40 cases)according to random number table method.The observation group used the ultra-early small bone window intracranial hematoma removal,and the control group performed traditional bone valve craniotomy hematoma clearance.The hematoma clearance rate,operation time,intraoperative bleeding volume,the treatment effect and the dynamic changes of neuron-specific enolase(NSE)and S100 protein(S100)before and after operation were compared between the two groups,and the complications of the two groups were recorded.Results The amount of bleeding of the observation group was lower than that of the control group,and the operation time of the observation group was shorter than that of the control group,there were statistically significant(P＜0.05).The levels of S100 and NSE at the time points of the observation group were lower than those of the control group,and there were statistically significant(P＜0.05).There was no statistically significant in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Ultra-early small bone window intracranial hematoma removal and large bone flap craniotomy removal are equivalent in the treatment of hypertensive cerebral hemorrhage,and the security is equivalent,but the former has more advantages in terms of operation time,blood loss,and trauma to the patient. 2022 Vol. 29 (10): 85-88 [Abstract] ( 32 ) HTML (1 KB)  PDF (528 KB)  ( 67 ) 89 Clinical effect of Wuling Capsules on sleep disorders induced by hormone pulse therapy for nephrotic syndrome WANG Jiang; ZHU Juqi ;SHI Chunzhen ;XIONG Qingdi ;YI Qinxia Objective To explore the treatment effect of Wuling Capsules on sleep disorders induced by hormone pulse therapy for nephrotic syndrome.Methods A total of 100 patients with sleep disorders caused by hormone shock therapy for primary nephrotic syndrome in Jiujiang Hospital of Traditional Chinese Medicine from June 2019 to June 2020 were selected as the study subjects,and they were divided into the Wuling Capsules group(50 cases)and the Estazolam group(50 cases)according to the odd and even bed numbers.The Wuling Capsules group was treated with Wuling Capsules,and the Estazolam group was given Estazolam for treatment.The efficacy and Pittsburgh sleep quality index(PSQI),treatment emergent symptom scale(TESS)and the incidence rates of adverse reactions after treatment were compared between the two groups.Results The effective rate in the Wuling Capsules group at 6 weeks of treatment was higher than that in the Estazolam group,the difference was statistically significant(P＜0.05).The PSQI scores of the two groups showed decreasing trends at 6 weeks of treatment(P＜0.05),and the PSQI scores at 1,3 and 6 weeks of treatment in the Wuling Capsules group were lower than those in the Estazolam group,the differences were statistically significant(P＜0.05).The PSQI scores of the two groups showed significant upward trends after drug withdrawal(P＜0.05),and the PSQI scores at 1,3 and 6 weeks after drug withdrawal in the Wuling Capsules group were lower than those in the Estazolam group,the differences were statistically significant(P＜0.05).The TESS score in the Wuling Capsules group was lower than that in the Estazolam group,the difference was statistically significant(P＜0.05).The incidence rate of adverse reactions in the Wuling Capsules group was lower than that in the Estazolam group,the difference was statistically significant(P＜0.05).Conclusion Compared with Estazolam,the application of Wuling Capsules for patients with sleep disorders induced by hormone pulse therapy for nephrotic syndrome can better enhance the efficacy,improve the sleep quality and reduce the occurrence of adverse reactions. 2022 Vol. 29 (10): 89-91转95 [Abstract] ( 34 ) HTML (1 KB)  PDF (588 KB)  ( 81 ) 92 Comparison of application effects of Tetracaine Mortar and Paraffin Oil in urinary catheter indwelling after percutaneous nephrolithotomy XIE Dan ;ZHANG Xiaoling; LUO Lei ;CHEN Yin ;ZHAO Jun ;HUA Chenglong ;CHEN Xue Objective To compare the application effects of Tetracaine Mortar and Paraffin Oil in urinary catheter indwelling after male genitourinary system surgery.Methods A total of 83 patients with percutaneous nephrolithotomy under general anesthesia admitted to Operating Room of the 908th Hospital of China People's Liberation Army Joint Logistic Support Force from January 2017 to August 2021 were selected as the study subjects.According to the random number table method,the patients were divided into in the Tetracaine group(42 cases)and in the Paraffin Oil group(41 cases).The Tetracaine group was given Tetracaine Mortar for urinary catheter indwelling,and the Paraffin Oil group was given Paraffin Oil for urinary catheter indwelling.The hemodynamic changes at drug injection(T0)and at 5 min(T1),10 min(T2)and 30 min(T3)after removal of tracheal catheter,postoperative emergence agitation and comfort and urethral irritation response at 8,24 and 48 h after surgery were compared between the two groups of patients.Results The heart rate(HR)and mean arterial pressure(MAP)showed downward trends,while the blood oxygen saturation(SpO2)showed an upward trend in the Tetracaine group,but there were no obvious changes in HR and MAP and SpO2 showed an upward trend in the Paraffin Oil group.There were no statistical differences in the levels of HR,MAP and SpO2 between the two groups at T0(P＞0.05).The level of HR of the Tetracaine group at T1,T2 and T3 were slower than those of the paraffin oil group,and the level of MAP of the Tetracaine group at T1,T2 and T3 were lower than those of the Paraffin Oil group,the differences were statistically significant(P＜0.05).There were no statistical significances in the levels of SpO2 at T1,T2 and T3 between the two groups(P＞0.05).The postoperative emergence agitation score in the Tetracaine group was lower than that in the Paraffin Oil group,the difference was statistically significant(P＜0.05).The GCQ score of the two groups showed a gradually increasing trend,and the GCQ scores in the Tetracaine group at 12,24 and 48 h after surgery were higher than those in the Paraffin Oil group,the differences were statistically significant(P＜0.05).The incidence rate of urethral irritation response in the Tetracaine group was lower than that in the Paraffin Oil group,the difference was statistically significant(P＜0.05).Conclusion The application of Tetracaine Mortar in urinary catheter indwelling after male genitourinary system surgery is beneficial to stabilizing the heart rate and mean arterial pressure,relieving the postoperative emergence agitation,improving the postoperative comfort and reducing the urethral irritation of patients. 2022 Vol. 29 (10): 92-95 [Abstract] ( 43 ) HTML (1 KB)  PDF (579 KB)  ( 49 ) 96 Application of acupuncture analgesia in the perioperative period of transperineal prostate puncture SHEN Siyao; LI Jianmin ;ZENG Zhigang ;ZHAO Hong ;ZENG Xiaochun ;XU Dajin ;ZENG Jingwen Objective To study the application effect of acupuncture analgesia in the perioperative period of transperineal prostate puncture.Methods From January 2018 to February 2021,60 patients undergoing transperineal prostate puncture in Jiangxi Integrated Traditional Chinese and Western Medicine Hospital were selected as the research subjects.They were divided into the observation group(30 cases)and the control group(30 cases)according to random number table methods.The observation group was treated with acupuncture analgesia combined with prostate peripheral nerve block anesthesia,and the control group was treated with prostate nerve block anesthesia alone.The operation time of the two groups was compared,the pain degree evaluating with visual analogue scale(VAS)score at different time points,and the difference levels of blood pressure and heart rate at different time points were compared between the two groups.Results There was no significant difference in the operation time between the two groups(P＞0.05).The VAS score level of the two groups during local anesthesia and puncture were higher than those of the probe placement,and the VAS score of the needle of the two groups were lower than those of the probe,the differences were statistically significant(P＜0.05).The VAS scores of the observation group during probe placement,local anesthesia,puncture and needle acupuncture were significantly lower than those of the control group,the differences were statistically significant(P＜0.05).There was no significant difference in the difference levels of blood pressure and heart rate between the observation group after anesthesia,puncture and after puncture(P＞0.05).There was no significant difference in the difference levels in the heart rate between the control group after anesthesia,puncture and after puncture(P＞0.05).There was no significant difference in the difference levels of blood pressure between the two groups after puncture(P＞0.05).The difference level of blood pressure during and after puncture in the control group was lower than that after anesthesia,the difference was statistically significant(P＞0.05).The difference level of blood pressure after anesthesia and puncture in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).The difference level of heart rate after anesthesia,puncture and after puncture in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).Conclusion Acupuncture analgesia has a good effect in the perioperative period of transperineal prostate puncture,which can reduce the pain of patients and stabilize the levels of perioperative blood pressure and heart rate. 2022 Vol. 29 (10): 96-99 [Abstract] ( 65 ) HTML (1 KB)  PDF (543 KB)  ( 61 ) 100 Risk factors analysis of urinary incontinence after transurethral excision of the prostate by laser vaporization in patients with benign prostatic hyperplasia ZOU Gengui Objective To analyze the risk factors of urinary incontinence(UI)after transurethral excision of the prostate by laser vaporization in patients with benign prostatic hyperplasia(BPH).Methods The clinical data of 200 patients with BPH treated by transurethral excision of prostate by laser vaporization(TULP)from July 2020 to July 2021 in Shangrao People's Hospital were retrospectively collected.They were divided into the UI group(43 cases)and the non-UI group(157 cases)according to the postoperative UI.The general data of the two groups were compared.The risk factors of UI after TULP in BPH patients was analyzed by multivariate logistic regression.Results Multivariate logistic regression analysis showed that advanced age(β=1.372, OR=3.943,95%CI=2.411-6.449, P＜0.001),large prostate volume(β=2.184, OR=8.882,95%CI=6.084-12.965, P＜0.001),long operation time(β=1.427, OR=4.166,95%CI=1.483-11.704, P=0.007),low temperature of bladder flushing fluid(β=2.342, OR=10.402,95%CI=7.425-14.572, P＜0.001),large volume of catheter balloon injection(β=2.583,OR=13.237,95%CI=3.791-46.223,P＜0.001),constipation(β=1.263,OR=3.536,95%CI= 1.699-7.360, P＜0.001),and no preoperative pelvic floor muscle training(β=1.735, OR=5.669,95%CI=2.288-14.048, P=0.007)were independent risk factors for postoperative UI in BPH patients(P＜0.05).Conclusion The risk factors of UI after TULP in BPH patients include advanced age,large prostate volume,long operation time,low temperature of bladder flushing fluid,large volume of catheter balloon injection,constipation,and no preoperative pelvic floor muscle training, etc.According to this,clinical treatment and intervention can be carried out for BPH patients after TULP to reduce the risk of UI after operation. 2022 Vol. 29 (10): 100-102转106 [Abstract] ( 41 ) HTML (1 KB)  PDF (560 KB)  ( 60 ) 103 Influence of peritoneal dialysis and hemodialysis in the treatment of endstage renal disease on natural killer cells and T cell subsets YANG Bo Objective To explore and analyze the influence of peritoneal dialysis and hemodialysis in the treatment of end-stage renal disease on natural killer cells and T cell subsets.Methods A total of 120 patients with end-stage renal disease admitted to Xincheng Hospital of Liaoyang City Central Hospital of Liaoning Province from January 2019 to January 2021 were selected as the study objects,and they were divided into the peritoneal dialysis group and the hemodialysis group by random number table methods,60 cases in each group.The peritoneal dialysis group was given peritoneal dialysis,the hemodialysis group was given hemodialysis.The changes of the levels of natural killer cells(NK cell ratio,NK cell activity)and T cell subsets(CD3+,CD4+,CD8+,CD4/CD8)were compared between the two groups.Results After treatment,the ratio of NK cells and NK cell activity between the two groups were lower than those before treatment,and the ratio of NK cells and NK cell activity after treatment in the peritoneal dialysis group were higher than those in the hemodialysis group,the differences were statistically significant(P＜0.05).After treatment,the levels of CD3+,CD8+ of the two groups were higher than those before treatment,the levels of CD4+ and CD4/CD8 of the two groups were lower than those before treatment,and the level of CD8+after treatment in the peritoneal dialysis group was higher than that before treatment,the differences were statistically significant(P＜0.05).The levels of CD3+ after treatment in the peritoneal dialysis group was lower than that in the hemodialysis group,and the levels of CD4+,CD8+ and CD4/CD8 after treatment in the peritoneal dialysis group were higher than those in the hemodialysis group after treatment,the differences were statistically significant(P＜0.05).Conclusion Peritoneal dialysis and hemodialysis in the treatment of end-stage renal disease can have a strong regulatory effect on natural killer cells and T cell subsets,and have less impact on cellular immune function.The effect of the former is more prominent than that of the latter. 2022 Vol. 29 (10): 103-106 [Abstract] ( 39 ) HTML (1 KB)  PDF (554 KB)  ( 80 ) 107 Clinical efficacy of Dapagliflozin combined with Metformin in the patients with type 2 diabetes mellitus TIAN Rui; BEN Lyuhong Objective To investigate the efficacy and safety of Dapagliflozin combined with Metformin in the patients with type 2 diabetes mellitus and provide evidence of clinical trantment.Methods A total of 105 patients newly diagnosed with T2DM in DongGuan Tungwah Hospital from May 2019 to August 2020 were selected as the research objects.According to the simple randomized principle,the patients were divided into the Dapagliflozin group(27 patients),Saxagliptin group(26 patients),Acarbose group(27 patients)and Glimepiride group(25 patients).All groups were simultaneously treated with Metformin for 12 weeks.Body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),fasting blood glucose(FPG),2 hours postprandial blood glucose(PBG),glycated hemoglobin(HbA1c),islet β-cell function index(HOMA-β),serum uric acid(SUA),serum creatinine(SCr),total cholesterol(TC)and triacylglycerin in 4 groups were compared(TG),alanine aminotransferase(ALT),alanine aminotransferase(AST)levels and adverse reactions were cimpared among the four groups.Results Before treatment,there were no significant differences in BMI,SBP,DBP,FPG,PBG,HbA1c,SUA,SCr,TC,TG,ALT and AST among the four groups(P＞0.05).After treatment,the levels of FPG,PBG,HbA1c and HOMA-β in the four groups were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,The BMI,SBP,TC,TG and SUA of Dagaglipin group were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,FPG,HbA1c,HOMA-β,BMI,SBP,TG and SUA in Dagagliptin group were lower than those in Saxagliptin group,Acarbose group and Glimepirea group(P＜0.05).The total incidence of adverse events in the Dagagligin group was 3.7%,lower than that in the Acarbose group(29.6%),and the difference was statistically significant(P＜0.05).Conclusion Dapagliflozin plus Metformin have better treatment results in patients with T2DM mellitus.It can effectively reduce blood glucose fluctuations,and improve many metabolic indexes.There is no obvious gastrointestinal reaction and high safety,which is worthy of promotion. 2022 Vol. 29 (10): 107-110 [Abstract] ( 34 ) HTML (1 KB)  PDF (411 KB)  ( 117 ) 111 Effect of local injection of Triamcinolone Acetonide combined with Levothyroxine Sodium in the treatment of Hashimoto's thyroiditis SUN Chuang Objective To explore and analyze the curative effect of local injection of Triamcinolone Acetonide combined with Levothyroxine Sodium in the treatment of Hashimoto's thyroiditis and its effect on serum visfatin and cytokines.Methods A total of 120 patients with Hashimoto's thyroiditis were treated in the Xincheng Hospital of Liaoyang Central Hospital selected from May 2018 to May 2020,the patients were divided into the control group and the observation group by random number table method,with 60 cases in each group.Control group was treated with Levothyroxine Sodium,and observation group was treated with local Triamcinolone Acetonide injection on the basis of control group.The efficacy,thyroid indexes,serum lipins and cytokines expression levels and the incidence of adverse reactions were compared between the two groups after 12 weeks of continuous treatment.Results The total clinical effective rate in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).After treatment,the levels of thyroid stimulating hormone(TSH),thyroglobulin antibody(TGAb),thyroid microsomal antibody(TMAb),serum lipin,recombinant differentiated protein cluster 195(CD195)and recombinant differentiated protein cluster 30(CD30)in observation group were lower than those in control group,serum free triiodothyronine(FT3)and serum free thyroxine(FT4)were higher than those in control group,the differences were statistically significant(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion The addition of local injection of Triamcinolone Acetonide to the treatment of Hashimoto's thyroiditis by Levothyroxine Sodium can better relieve clinical symptoms and signs,regulate thyroid-related indicators,improve serum visfatin and cytokine expression levels,and no obvious adverse reactions were seen during the treatment,and the safety is guaranteed. 2022 Vol. 29 (10): 111-114 [Abstract] ( 34 ) HTML (1 KB)  PDF (397 KB)  ( 50 ) 115 Effect of Dexmedetomidine combined with Ropivacaine for transversus abdominis plane block on analgesia after open liver resection XIA Yanchun; HUANG Yisheng; HUANG Huimin Objective To explore the analgesic effect of Dexmedetomidine combined with Ropivacaine for transverse abdominal muscle block(TAP)after open hepatectomy.Methods A total of 50 hepatectomy patients admitted to Ganzhou People's Hospital from August 2020 to August 2021 were selected as the research subjects,and were divided into experimental group and control group according to random number table method,with 25 patients in each group.After endotracheal intubation,bilateral subcostal margin TAP block was performed in both groups under ultrasound guidance.The control group was given Ropivacaine for local anesthesia,and the experimental group was given Ropivacaine combined with Dexmedetomidine for local anesthesia.Sufentanil + Butorphanol + Tropisetron were used for patient-controlled intravenous analgesia(PCIA)before suturing.The time of first complaint of pain,time of eating and time of getting out of bed were compared between the two groups.Visual analogue scale(VAS)was used to evaluate the pain of 2,4,6 and 12 h after surgery in two groups.Heart rate(HR)and mean arterial pressure(MAP)were compared between the two groups at 30,60,120 and 180 min after surgery,and the incidence of adverse reactions within 24 h after surgery was statistically analyzed between the two groups.Results The experimental group complained of pain for the first time later than the control group,eating time and out of bed activity time earlier than the control group,the differences were statistically significant(P＜0.05).VAS score of experimental group was lower than that of control group at 2,4,6,12 h after operation,the differences were statistically significant(P＜0.05).HR and MAP of experimental group were lower than those of control group at 30,60,120 and 180 min after operation,the differences were statistically significant(P＜0.05).The total incidence of adverse reactions 24 h after operation in the experimental group was 12.00%,lower than 32.00% in the control group,the difference was statistically significant(P＜0.05).Conclusion Dexmedetomidine combined with Ropivacaine can effectively prolong the analgesic time for patients with TAP undergoing open liver resection.Dexmedetomidine can play a sedative and stable circulation effect after slowly absorbing into the blood,and can effectively reduce the occurrence of related adverse reactions,with high effectiveness and safety 2022 Vol. 29 (10): 115-118 [Abstract] ( 32 ) HTML (1 KB)  PDF (421 KB)  ( 101 ) 119 Application effect of stellate ganglionic block in spinal surgery of elderly patients DENG Luntong; HU Haitao ;MEI Haixiang Objective To investigate the application effect of stellate ganglionic block in spinal surgery of elderly patients.Methods A total of 80 spinal surgery elderlypatients admitted to Jiangxi Hospital of Integrated Traditional Chinese and Western Medicine from June 2019 to August 2021 were selected as the study subjects,and divided into control group(40 cases)and observation group(40 cases)by random number table method.Both groups were given general anesthesia.The observation group underwent ultrasound guided stellate ganglionic block,and the control group was injected with the same amount of normal saline in the same way.The level of postoperative cognitive dysfunction was compared between the two groups at 1 day before surgery and 7 days after surgery.The changes of brain oxygen metabolism and the incidence of adverse reactions were compared between the two groups before and after treatment.Results After 7 days of treatment,the mini-mental state examination scale(MMSE)score and the Montreal cognitive assessment scale(MoCA)score of observation group were higher than those of the control group,the differences were statistically significant(P＜0.05).After 7 days of treatment,brain tissue carbon dioxide tension(PtiCO2)of the observation group was lower than that of the control group,while brain tissue oxygen tension(PtiO2)and jugular venous oxygen saturation(Sjv[O2])were higher than those of the control group,the differences were statistically significant(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Stellate ganglionic block can improve cognitive function in elderly patients undergoing spinal surgery,with high safety. 2022 Vol. 29 (10): 119-121 [Abstract] ( 39 ) HTML (1 KB)  PDF (412 KB)  ( 45 ) 122 Application research of transvaginal ultrasound combined with real-time tissue elastography in the diagnosis of cervical cancer and parametrial invasion PENG Wei Objective To evaluate the diagnostic value of transvaginal ultrasound combined with real-time tissue elastography in cervical cancer and parametrial invasion.Methods A total of 60 patients with suspected cervical cancer in the Department of Gynecology,Pingxiang People's Hospital from July 2020 to July 2021 were selected as the study subjects.All patients underwent transvaginal ultrasound and real-time tissue elastography.The diagnostic value of transvaginal ultrasound combined with real-time tissue elastography was analyzed using pathological results as the gold standard.Results Pathological results showed that 54 patients were positive and 6 patients were negative.The positive rate of transvaginal ultrasound combined with real-time tissue elastography was 90.00%,higher than that of transvaginal ultrasound(75.00%),and the difference was statistically significant(P ＜0.05).The diagnostic sensitivity of transvaginal ultrasound combined with real-time tissue elastography was higher than that of transvaginal ultrasound,and the rate of missed diagnosis was lower than that of transvaginal ultrasound,and the differences were statistically significant(P＜0.05).Conclusion Vaginal ultrasound combined with real-time tissue elastography can effectively diagnose the disease status and judge whether there is parauterine infiltration,has high application value in patients with cervical cancer. 2022 Vol. 29 (10): 122-124转139 [Abstract] ( 40 ) HTML (1 KB)  PDF (749 KB)  ( 49 ) 125 Diagnostic value of coronary angiography with electrocardiograph gating multislice spiral CT ZHANG Jiquan; ZHAO Hui Objective To investigate the diagnostic value of coronary artery disease(CHD)by electrocardiograph gating multi-slice spiral CT(MSCT).Methods A total of 116 patients with suspected CHD admitted to Xianning First People's Hospital from January 2018 to January 2021 were selected as the study subjects.All patients underwent MSCT examination,and coronary angiography(CAG)was used as the gold standard to evaluate the coronary artery imaging of each segment,and the consistency between the diagnostic results of MSCT coronary angiography and coronary angiography was analyzed.Results A total of 1712 coronary segments with diameter ≥1.5 mm were detected by MSCT in 116 patients,of which 49 segments could not be evaluated,with an assessable rate of 97.14%.A total of 1608 segments were consistent with gold standard CAG.There was no significant difference between MSCT and CAG in the grading of coronary stenosis(P＞0.05).The positive rates of MSCT and CAG were 26.22% and 24.71%,respectively,and there was no significant difference between them(P＞0.05).The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of MSCT in diagnosing coronary stenosis were 94.50%,95.52%,95.25%,88.22% and 97.99%,respectively.The diagnostic results of MSCT were highly consistent with gold standard CAG(Kappa＞0.75).Conclusion Electrocardiograph gating dual-source CT coronary angiography has a high clinical diagnostic value in the evaluation of coronary artery disease stenosis,and the diagnostic results are in good agreement with the gold standard. 2022 Vol. 29 (10): 125-127 [Abstract] ( 30 ) HTML (1 KB)  PDF (418 KB)  ( 32 ) 128 Comparisons of the clinical effect of Losartan and Captopril in the treatment of hypertensive nephropathy LIN Xiujuan; CHEN Jinzao; ZHENG Liru Objective To explore the clinical effects of Losartan and Captopril in the treatment of hypertensive nephropathy.Methods A total of 60 patients with hypertensive nephropathy admitted to the Department of Cardiology of the First Hospital of Putian From July 2020 to June 2021 were selected as the research subjects,they were divided into Losartan group and Captopril group by drawing lots method,with 30 cases in each group.Two groups of patients were treated with Losartan and Captopril respectively.The systolic and diastolic blood pressures,estimated glomerular filtration rate(eGFR),the difference between the eGFR(△eGFR)before and after treatment and the total incidence of complications during the treatment were compared between the two groups.The blood creatinine levels of the two groups were collected and were used for the calculations of the eGFR.Results Before treatment,there were no significant differences in systolic blood pressure,diastolic blood pressure,and eGFR between the two groups(P＞0.05).After treatment,the systolic blood pressure of the two groups was lower than that before treatment,and the systolic blood pressure of the Losartan group was lower than that of the Captopril group,the differences were statistically significant(P＜0.05).After treatment,the diastolic blood pressure of the two groups was lower than that before treatment,and the diastolic blood pressure of the Losartan group was lower than that of the Captopril group,the differences were statistically significant(P＜0.05).After treatment,the eGFR of the two groups was higher than that before treatment,and the eGFR of the Losartan group was higher than that of the Captopril group,the differences were statistically significant(P＜0.05).After treatment,△eGFR in the Losartan group was higher than that of the Captopril group,and the difference was statistically significant(P＜0.01).The total incidence of the complications in the Losartan group(13.30%)was lower than that in the Captopril group(36.70%),the difference was significant(P=0.037).Conclusion From the effect of lowering blood pressure and improving renal function,both drugs can reduce blood pressure,improve renal function and reduce the incidence of adverse drug reactions,thereby preventing the progression of renal disease.Losartan is better than Captopril in the treatment of hypertensive nephropathy. 2022 Vol. 29 (10): 128-131 [Abstract] ( 43 ) HTML (1 KB)  PDF (416 KB)  ( 88 ) 132 Effect of Morphine Sustained Release Tablets and Oxycodone Sustained Release Tablets on moderate and severe cancer pain LIU Man ;WU Shan ;ZHAO Sen; XU Baoli Objective To investigate the effect of Morphine Sustained Release Tablets and Oxycodone Sustained Release Tablets in moderate and severe cancer pain.Methods A total of 100 patients with moderate and severe cancer pain admitted to Zhongshan Hospital Affiliated to Dalian University from April 2019 to February 2021 were selected as research objects,they were divided into control group and observation group according to random number table method,with 50 cases in each group.The control group was treated with Morphine Sustained Release Tablets and the observation group was treated with Oxycodone Sustained Release Tablets.The analgesic efficiency,effective time of pain control and adverse reactions of the two groups were compared.Results There was no significant difference in the scores of numerical rating scale(NRS)between the two groups before treatment(P＞0.05).After treatment,the NRS score of the observation group was lower than that of the control group,the difference was statistically significant(P＜0.05).The effective time of the observation group was shorter than that of the control group,the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the observation group(8%)was lower than that of the control group(32%),the difference was statistically significant(P＜0.05).Conclusion In the treatment of moderate and severe cancer pain,the effect of Morphine Sustained Release Tablets and Oxycodone Sustained Release Tablets are basically the same,but Oxycodone Sustained Release Tablets have faster effect and less adverse reactions.Clinical administration can be selected according to the actual situation. 2022 Vol. 29 (10): 132-134 [Abstract] ( 41 ) HTML (1 KB)  PDF (404 KB)  ( 47 ) 135 Application effect of "three-step and seven-method" massage in adolescent idiopathic scoliosis XU Rui ;HUANG Jian Objective To explore the effect of "three steps and seven methods" massage in adolescent idiopathic scoliosis(AIS).Methods A total of 60 AIS patients admitted to the Affiliated Rehabilitation Hospital of Fujian University of Traditional Chinese Medicine from March 2020 to March 2021 were selected as the research subjects.They were divided into treatment group and control group by random number table method,with 30 patients in each group.The two groups of patients were treated with basic symptomatic treatment,the treatment group was treated with "three-step and seven-method" massage therapy,and the control group was treated with exercise therapy(referring to Schroth orthopaedic gymnastics),and the intervention cycle was 8 weeks.Cobb angle,scoliosis SRS-22 score questionnaire,lumbar flexion and extension muscle strength and range of motion by Turgumed mechanical test system before and after treatment and clinical efficacy were compared between the two groups.Results After treatment,Cobb angle of the two groups were lower than those before treatment,and Cobb angle of treatment group was lower than that of control group,the differences were statistically significant(P＜0.05).After treatment,the SRS-22 questionnaire score of the two groups were higher than those before treatment,and the SRS-22 questionnaire score of treatment group was higher than that of control group,the differences were statistically significant(P＜0.05).After treatment,muscle strength and activity measured by Turgumed mechanical test system in the two groups were higher than those before treatment,and muscle strength and activity measured by Turgumed mechanical test system in treatment group were higher than those of control group,the differences were statistically significant(P＜0.05).The total effective rate in treatment group was higher than that in control group,and the difference was statistically significant(P＜0.05).Conclusion The "three steps and seven methods" massage can effectively improve spinal biomechanics,improve quality of life and promote disease recovery in patients with AIS. 2022 Vol. 29 (10): 135-139 [Abstract] ( 70 ) HTML (1 KB)  PDF (517 KB)  ( 151 ) 140 Clinical study of acupoint application combined with modified Xiaoyao Powder in the treatment of premenstrual syndrome LIAO Chaoqing; ZHONG Haiying; XIAO Xiaofeng; XIAO Zhaohua; QIU Jing Objective To explore the clinical effect of acupoint application combined with modified Xiaoyao Powder in the treatment of premenstrual syndrome(PMS).Methods A total of 60 patients with PMS identified as liver qi stagnation who were admitted to Xinyu Hospital of Traditional Chinese Medicine from November 2019 to November 2021 were selected as the research subjects.They were divided into single group and combined group by drawing lots,with 30 cases in each group.Single group was treated with Xiaoyao Powder addition and subtraction,and combined group was treated with Xiaoyao Powder addition and subtraction combined with acupoint application.The traditional Chinese medicine symptom score,treatment effect and Hamilton anxiety scale(HAMA)score of the two groups were compared.Results After treatment,the traditional Chinese medicine syndrome scores of the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,the traditional Chinese medicine syndrome score of the combined group was lower than that of the single group,the difference was statistically significant(P＜0.05).The total effective rate of combined group was higher than that of single group,and the difference was statistically significant(P＜0.05).After treatment,HAMA scores in the two groups were lower than those before treatment,the differences were statistically significant(P＜0.05).After treatment,HAMA score of the combined group was lower than that of the single group,the difference was statistically significant(P＜0.05).Conclusion Acupoint application combined with modified Xiaoyao Powder can significantly improve PMS-related symptoms and improve the anxiety of patients. 2022 Vol. 29 (10): 140-142转146 [Abstract] ( 38 ) HTML (1 KB)  PDF (518 KB)  ( 89 ) 143 Clinical effect of Qufeng Decoction on patients with maintenance hemodialysis skin pruritus CHEN Jianqiang ;ZHENG Zerong ;WU Tangying Objective To investigate the effect of modified Qufeng Decoction on serum calcium(Ca)and serum phosphorus(P)in patients with pruritus on maintenance hemodialysis(MHD).Methods A total of 106 patients with MHD skin pruritus who were admitted to the Second Hospital of Traditional Chinese Medicine in Zhanjiang City,Guangdong Province from February 2020 to March 2021 were selected as the research subjects.They were divided into conventional group and traditional Chinese medicine treatment group by coin toss method,with 53 cases in each group.The conventional treatment group was treated with conventional treatment,and the traditional Chinese medicine treatment group was treated with Qufeng Decoction.Skin prurtication,Ca,P,iPTH blood indexes,tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),interleukin-8(IL-8)inflammatory indexes were compared between the two groups.Results After treatment,the visual analogue scale(VAS)score of patients in traditional Chinese medicine treatment treatment group was lower than that in conventional group,and the difference was statistically significant(P＜0.05).The Ca level in traditional Chinese medicine treatment treatment group was higher than that in conventional group,while the P and iPTH levels were lower than those in conventional group,the differences were statistically significant(P＜0.05).The levels of TNF-α,IL-6 and IL-8 in traditional Chinese medicine treatment treatment group were lower than those in conventional group,the differences were statistically significant(P＜0.05).Conclusion Qufeng Decoction treatment can inhibit the secretion of inflammatory factors,maintain the balance of blood calcium and phosphorus metabolism,and improve the symptoms of skin itching in MHD patients. 2022 Vol. 29 (10): 143-146 [Abstract] ( 38 ) HTML (1 KB)  PDF (509 KB)  ( 97 ) 147 Correlation between hope level and anxiety,depression and coping style of patients after percutaneous coronary intervention PENG Ting ;HE Pingping; LEI Qiong ;LI Junyi Objective To explore the correlation of hope level,anxiety,depression and coping style of patients after percutaneous coronary intervention(PCI).Methods A total of 140 patients admitted to the First Affiliated Hospital of University of South China from February to April 2021 after PCI were selected as research objects according to convenient sampling method.They were investigated by herth hope index(HHI),self-rating anxiety scale(SAD),self-rating depression scale(SDS)and medical coping modes questionnaire(MCMQ).Results The hope level score of patients after PCI was(29.96±2.06)points,the anxiety was(55.38±8.29)points,the depression score was(53.63±7.01)points.The“avoidance”coping style scored highest with(18.89±1.24)points.The hope level was negatively correlated with anxiety(r=-0.387, P＜0.01),depression(r=-0.416, P＜0.01),“avoidance”(r=-0.168, P＜0.05)and“submission”coping style(r=-0.339, P＜0.01),but positively correlated with“facing”coping style(r=0.179, P＜0.05).Conclusion The hope level of patients after PCI is closely related to anxiety,depression and coping style.Medical staff should strengthen the psychological support of patients after PCI,reduce anxiety and depression,so as to improve the hope level and promote positive coping mode. 2022 Vol. 29 (10): 147-150 [Abstract] ( 38 ) HTML (1 KB)  PDF (503 KB)  ( 59 ) 151 Analysis on the influencing factors of ICU nurses' recessive absenteeism and its correlation with emotional intelligence in tertiary hospitals of Bengbu city XU Xiaoyan Objective To explore the influencing factors of implicit absenteeism and its correlation with emotional intelligence among intensive care unit(ICU)nurses in the tertiary hospitals of Bengbu.Methods A total of 279 ICU nurses in the tertiary hospitals of Bengbu from March to June 2021 were selected as the research subjects.The questionnaires were applied to collect data including demographic information,implicit absenteeism,and emotional intelligence levels.Analyze the influencing factors of implicit absenteeism and the relationship between implicit absenteeism and emotional intelligence.Results The total score of implicit absenteeism and emotional intelligence of ICU nurses were(21.33±5.80)and(121.34±32.81),and there was a negative correlation between implicit absenteeism and emotional intelligence(total score and each dimensions)(P＜0.05).Univariate analysis revealed that age,gender,professional title,and average number of night shift per month were the related factors of implicit absenteeism score of ICU nurses(P＜0.05).Multivariate analysis of influencing implicit absenteeism scores of ICU nurses revealed that age,gender,professional title,average number of night shifts per month were the influencing factors of implicit absenteeism scores of ICU nurses(P＜0.05).Conclusion The ICU nurses had a high level of implicit absenteeism,which was affected by age,gender,professional title,average number of monthly night shift.The high level of emotional intelligence was helpful to reduce the occurrence of implicit absenteeism. 2022 Vol. 29 (10): 151-154 [Abstract] ( 33 ) HTML (1 KB)  PDF (554 KB)  ( 35 ) 155 Problems and rectification analysis of filling in medicine expenses and treatment information on the first page of traditional Chinese medicine medical records WANG Liqin1;GU Jing Objective The Chinese medicine cost information,diagnosis and treatment information on traditional Chinese medicine medical record homepage appeared error in the logical verification.Based on the phenomenon,this study analyzes the causes of logical verification errors in the front page of traditional Chinese medicine medical records in Lishui Hospital of Traditional Chinese Medicine,and puts forward rectification measures.Methods According to the rules for filling out the first page of traditional Chinese medicine medical record homepage and comparing with the performance interface standards of national public hospitals,a logical verification report for the first page of medical records was developed in the medical record management system.The archived medical records were obtained from January 2019 to December 2020.Firstly,this study performed verification according to the treatment category and Chinese medicine fee.Subsequently,the medical institution preparations filling and medical institution preparations fees were used for verification.Finally,the rule of Chinese medicine diagnosis and treatment technology to formulate and Chinese medicine(Chinese medicine and ethnic medicine medical services)are applied for verification.The data statistically analyzed that the departments had logical verification problems and the cost of each department was logically verified wrong.Results Among all archived medical records from January 2019 to December 2020,16 departments involved logical verification problems.During this period,24 158 medical records were filed from the 16 departments of the hospital and there were logical verification errors in 5121 medical records,accounting for 21.20%.The proportion of medical records with incorrect verifications of treatment categories and hospitalization expenses was 24.51%,41.20%of the medical records filled in with medical institutions' preparations and verified with medical institutions' preparation fees incorrectly.Additionally,the medical records with incorrect diagnosis and treatment technology and Chinese medicine(Chinese medicine and ethnic medicine medical services)that was checked incorrectly was also accounted for 34.29%.Conclusion The comparison of hospitalization expenses on the first page of traditional Chinese medicine medical records in Lishui District Hospital of traditional Chinese medicine needs to be improved.It is necessary to strengthen the communication with medical insurance department and clinical department to ensure the timeliness and accuracy of hospitalization expenses comparison.At the same time,logical verification is added to the link of clinicians writing medical records,so as to improve the writing quality of medical records and reduce the revise rate of paper medical records. 2022 Vol. 29 (10): 155-158 [Abstract] ( 53 ) HTML (1 KB)  PDF (546 KB)  ( 25 ) 159 Relationship between the nurses' personality traits and job satisfaction in pharmacy intravenous admixture service WANG Jinxiao; WANG Fang Objective To study the relationship between the nurses' personality traits and job satisfaction in pharmacy intravenous admixture service(PIVAS).Methods In this study,150 nurses in the PIVAS were investigated by Eysenck personality and job satisfaction survey.Results The job satisfaction of nurses in the PIVAS was basic satisfaction.There was significant difference in job satisfaction among nurses with different nursing age,marriage,education,professional title and income(P＜0.01).There was a negative correlation between psychoticism and praise and recognition(r=-0.27),sense of achievement(r=-0.28),salary and subsidy(r=-0.18),occupational characteristics(r=-0.21),management and hospital policy(r=-0.18),interpersonal relationship(r=-0.31)and the balance between family and hospital(r=-0.19)(P＜0.01).There was a positive correlation between concealment and being praised and recognized(r=0.33)and interpersonal relationship(r=0.26)(P＜0.01).Conclusion The overall job satisfaction level of nurses in the PIVAS is basic satisfaction,and the satisfaction level is relatively stable.Nursing age,marital status,educational background,professional title,income and other factors have different degrees of influence on the level of job satisfaction of nurses in the PIVAS.The variable dimensions of personality traits have a certain impact on the job satisfaction of nurses in the PIVAS. 2022 Vol. 29 (10): 159-163 [Abstract] ( 35 ) HTML (1 KB)  PDF (564 KB)  ( 36 ) 164 Effect of Qijiao moxibustion and acupoint application on osteoporotic vertebral compression fracture,abdominal distension and constipation WANG Yan ;XIONG Lijuan Objective To explore the nursing effect of Qijiao moxibustion combined with acupoint application on osteoporotic vertebral compression fractures,abdominal distension and constipation.Methods A total of 80 patients with osteoporotic vertebral compression fractures,abdominal distension and constipation from the Fourth Affiliated Hospital of Nanchang University from March 2019 to March 2021 were selected as the research objects.They were divided into observation group and control group by random number table method,with 40 cases in each group.Both groups were given routine nursing care.On this basis,the control group received acupoint application nursing intervention,and the observation group received Qijiao moxibustion combined with acupoint application nursing for 3 weeks.The clinical symptoms improvement time of the two groups after nursing(improvement time of abdominal distension and constipation symptoms)were compared,patient assessment of constipation quality of life scale(PAC-QOL)scores of the two groups were compared before nursing and at the end of 3 weeks of nursing.Results After nursing,the time to improve the symptoms of abdominal distension in the observation group was shorter than that of the control group,and the time to improve symptoms of constipation was shorter than that of the control group,the differences were statistically significant(P＜0.05).After 3 weeks of nursing,the PAC-QOL scores of the two groups were lower than those before nursing,and the score of observation group was lower than that of the control group,the differences were statistically significant(P＜0.05).Conclusion Qijiao moxibustion combined with acupoint application can shorten the time to improve the symptoms of abdominal distension and constipation in patients with osteoporotic vertebral compression fractures,abdominal distension and constipation,and improve their quality of life. 2022 Vol. 29 (10): 164-166转186 [Abstract] ( 40 ) HTML (1 KB)  PDF (673 KB)  ( 299 ) 167 Effect of Orem self-care theory on self-efficacy and postoperative complications of perioperative patients with benign prostatic hyperplasia YI Haiyan; SUN Yi Objective To explore the application effect of Orem self-care theory in perioperative patients with benign prostatic hyperplasia.Methods A total of 78 patients with benign prostatic hyperplasia treated in Yichun Second People's Hospital from September 2019 to September 2021 were selected as research objects.They were divided into two groups by random number table method,with 39 cases in each group.The control group was treated with routine intervention,and the observation group was treated with Orem self-care theory until the patient was discharged.The selfcare ability,self-efficacy,quality of life and the incidence of complications were compared between the two groups.Results The scores of self-care concept,health knowledge level,sense of self-care responsibility and self-care skills in the self-care ability measurement scale(ESCA)in the observation group after intervention were higher than those in the control group,with significant differences(P＜0.05).After intervention,the scores of general self-efficacy scale(GSEs)and the MOS item short from health survey(SF-36)scores in the observation group were higher than those in the control group,with significant differences(P＜0.05).The total incidence of complications in the control group was lower than that in the control group,with significant difference(P＜0.05).Conclusion Orem self-care theory can improve the self-care ability and self-efficacy of perioperative patients with benign prostatic hyperplasia,reduce the incidence of postoperative complications and improve the quality of life. 2022 Vol. 29 (10): 167-169 [Abstract] ( 41 ) HTML (1 KB)  PDF (663 KB)  ( 91 ) 170 Efficacy of nursing guidance and home supportive care in improving patency of autogenous arteriovenous fistulas in chronic kidney disease patients on maintenance hemodialysis ZHANG Guifeng;CAI Shufang; WANG Congzheng; CHANG Lingling;WANG Xiaocui Objective To investigate the efficacy of nursing guidance and home supportive care in improving patency of autogenous arteriovenous fistulas(AVF)in chronic kidney disease(CKD)patients on maintenance hemodialysis.Methods Sixty CKD patients with AVF initially established at the hemodialysis center of Shandong Weifang Yidu Central Hospital between January 2019 and March 2021 and initially entered dialysis were selected as research objects.The random number table method was applied to divide the enrolled patients into two groups on average.Autogenous AVF maintenance was performed in the home support nursing group(group A, n=30)by routine in-hospital nursing guidance plus home support nursing,and in the control group(group B, n=30)by routine in-hospital nursing guidance.The complications,such as AVF stenosis,AVF thrombosis,AVF infection,swelling hand syndrome,plagiarism syndrome,and AVF occlusion,were counted after 12 weeks of intervention in each of the two groups.The chi-square test was used to compare the difference in complication rates between the two groups,and the patency rates of the AVF in the two groups were compared and analyzed by the Kaplan Meier method.Results The patency rate of AVF at the end of 12 weeks of intervention in group A was higher than that in group B,with significant difference(P＜0.05).The total incidence of AVF related complications and failure rate in group A was lower than that in group B,with significant difference(P＜0.05).Conclusion The combination of nursing guidance and home supportive care is of great importance in improving the patency of autogenous AVF in CKD patients on maintenance hemodialysis,and is worth promoting in the clinic. 2022 Vol. 29 (10): 170-173 [Abstract] ( 35 ) HTML (1 KB)  PDF (732 KB)  ( 233 ) 174 Study on the value of cluster nursing in prevention of deep venous thrombosis of lower limbs after hemorrhagic shock of heterotopic pregnancy XU Li Objective To explore the effect of clustered nursing to prevent deep vein thrombosis of lower limbs after hemorrhagic shock of heterotopic pregnancy.Methods A total of 120 patients with hemorrhagic shock during heterotopic pregnancy who were admitted to Fuzhou First People's Hospital from June 2017 to June 2020 were selected as the research objects.They were divided into experimental group(60 cases)and control group(60 cases)by random number table method.The control group was given routine care,and the experimental group used the clustered care model on the basis of routine care.The postoperative time of getting out of bed,hospital stay and nursing time were compared between the two groups.The lower limb motor function of the two groups was compared after surgery.The incidence of postoperative lower extremity deep vein thrombosis and nursing satisfaction were compared between the two groups.Results The postoperative time of getting out of bed,hospital stay and nursing time in observation group were shorter than those in control group,and the differences were statistically significant(P＜0.05).After nursing,lower limb motor function of observation group was better than that in the control group,the difference was statistically significant(P＜0.05).The incidence of postoperative deep vein thrombosis in lower limbs in observation group was lower than that in control group,and the difference was statistically significant(P＜0.05).The nursing job satisfaction scores in of patients in the observation group were higher than those in the control group in care and love,service and technology,environment and guidance,total score,with statistically significant differences(P＜0.05).Conclusion Cluster nursing for patients with hemorrhagic shock of heterotopic pregnancy can effectively improve the recovery ability of patients' lower limb motor function,and improve patients' satisfaction with nursing work. 2022 Vol. 29 (10): 174-177 [Abstract] ( 36 ) HTML (1 KB)  PDF (657 KB)  ( 32 ) 178 Clinical study on improving symptoms of patients with asthmatic by auricular point pressing beans combined with traditional Chinese nursing based on syndrome differentiation LYU Biying; LI Haina ;ZHONG Jinrong ;YU Jieming Objective To explore the effect of improving symptoms of patients with asthmatic by auricular point pressing beans combined with traditional Chinese nursing based on syndrome differentiation.Methods A total of 80 patients with asthma syndrome admitted to the First Department of Internal Medicine of Yunfu Hospital of Traditional Chinese Medicine,the Second Affiliated Hospital of Guangdong Pharmaceutical University from June 2020 to May 2021 were selected as the research subjects.They were divided into control group and research group by random number table method,with 40 cases in each group.Patients in the control group were treated with standard routine nursing in respiratory medicine,while patients in the research group were treated with auricular point pressing beans combined with traditional Chinese nursing based on syndrome differentiation.Clinical symptoms,lung function,total nursing satisfaction,length of stay and nursing compliance of the two groups were observed before and after nursing.Results After nursing,the syndrome scores of shortness of breath,cough phlegm,asthma and phlegm sound,moss white and smooth,pulse string tight of patients in the two groups were lower than those before nursing,the differences were statistically significant(P＜0.05),and the syndrome scores of shortness of breath,cough phlegm,asthma and phlegm sound,moss white and smooth,pulse string tight of patients in the research group after nursing were lower than those in the control group,the differences were statistically significant(P＜0.05).After nursing,the forced expiratory volume in first second(FEV1),peak expiratory flow(PEF),ratio of forced expiratory volume in one second to forced vital capacity(FEV1/FVC)of patients in the two groups were higher than those before nursing,the differences were statistically significant(P＜0.05),and the FEV1,PEF and FEV1/FVC of patients in the research group after nursing were higher than those in the control group,the differences were statistically significant(P＜0.05).The total nursing satisfaction of patients in research group(97.50%)was higher than that in control group(80.00%),and the difference was statistically significant(P＜0.05).The length of hospitalization in research group was shorter than that in control group,and the difference was statistically significant(t=10.927,P＜0.05).The nursing compliance of patients in the research group was higher than that in the control group,the difference was statistically significant(χ2=6.267, P=0.012).Conclusion Auricular acupoint pressing beans combined with traditional Chinese nursing based on syndrome differentiation can improve the clinical symptoms and pulmonary function of patients with asthma,improve nursing satisfaction and nursing compliance,and shorten the length of hospital stay. 2022 Vol. 29 (10): 178-182 [Abstract] ( 37 ) HTML (1 KB)  PDF (671 KB)  ( 108 ) 183 Application of personalized care in the removal of complex impacted mandibular wisdom teeth with high-speed turbine combined with piezosurgery REN Aihua ;SUN Xiulan Objective To explore the effect of personalized care in the removal of complex impacted mandibular wisdom teeth with high-speed turbine combined with piezosurgery.Methods From January 2019 to June 2021,84 patients who underwent complex impacted mandibular tooth extraction at Dalian Stomatological Hospital were selected as the research subjects.They were divided into the control group and the observation group according to the random number table method,with 42 cases in each group.Both received high-speed turbine combined with piezosurgery extraction treatment.On this basis,the control group was given routine care,and the observation group was given routine care and personalized care.The operation time and the incidence of postoperative complications were compared between the two groups.Results The operation time of the observation group was shorter than that of the control group,and the difference was statistically significant(P＜0.05).The postoperative complication rate of the observation group was 2.38%,which was lower than the control group accounting for 14.29%,and the difference was statistically significant(P＜0.05).The visual analogue scale(VAS)score at 6 h after surgery and stitch removal in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion In the treatment of patients with complex impacted mandibular wisdom teeth with high-speed turbine combined with piezosurgery extraction,the application of personalized care can shorten the operation time,reduce the incidence of postoperative complications,and alleviate the degree of pain in a remarkable effect. 2022 Vol. 29 (10): 183-186 [Abstract] ( 38 ) HTML (1 KB)  PDF (672 KB)  ( 68 ) 187 Effect of Skinner program teaching intervention on sexual life quality and emotional state of patients after total hysterectomy YAO Lijuan; ZHANG Yuhua Objective To investigate the effect of Skinner program teaching intervention on the quality of sexual life and emotional state of patients after total hysterectomy.Methods A total of 96 patients who underwent total hysterectomy in Putian Medical District,the 900th Hospital of Joint Logistics Support Force from January 2019 to March 2020 were selected as the research subjects.They were divided into control group(n=48)and observation group(n=48)by random number table method.During hospitalization,patients in the control group received routine nursing,while patients in the observation group received Skinner program teaching intervention on the basis of the intervention in the control group.The sexual life quality,disease cognition and self-rating depression scale(SDS)and self-rating anxiety scale(SAS)scores of the two groups were compared before and after intervention.Results After intervention,the scores of sexual desire,orgasm,sexual satisfaction,sexual arousal,vaginal wetness and total score in observation group were higher than those in control group,the differences were statistically significant(P＜0.05).The awareness of disease-related knowledge in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).SDS and SAS scores in observation group were lower than those in control group,the differences were statistically significant(P＜0.05).Conclusion Skinner program teaching intervention can significantly improve the cognitive level of postoperative sexual life quality and disease-related knowledge of patients with total hysterectomy,and significantly improve the mood of depression and anxiety. 2022 Vol. 29 (10): 187-189转193 [Abstract] ( 36 ) HTML (1 KB)  PDF (699 KB)  ( 112 ) 194 Effect of health education and psychological nursing in patients with angina pectoris of coronary heart disease WANG Xin Objective To explore the clinical effect of health education and psychological nursing on angina pectoris of coronary heart disease.Methods A total of 100 patients with coronary heart disease and angina pectoris treated in the Fourth People's Hospital of Shenyang from March 2018 to February 2020 were selected as the research objects,they were divided into observation group and control group according to drawing lots method,with 50 cases in each group.The control group was given routine nursing,and the observation group was given health education and psychological nursing on the basis of the control group.The quality of life score and nursing satisfaction of the two groups were compared before and after the nursing.Results There was no significant difference in the score of quality of life between the two groups before nursing(P＞0.05).The quality of life scores of the two groups after nursing were higher than those before nursing,and the differences were statistically significant(P＜0.05).After nursing,the score of quality of life in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).After nursing,the total satisfaction of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05),Conclusion Patients with coronary heart disease and angina pectoris receiving health education and psychological nursing on the basis of routine nursing can improve their quality of life and their nursing satisfaction,which is conducive to improve the effect of clinical nursing and build a harmonious relationship between nurses and patients. 2022 Vol. 29 (10): 194-196 [Abstract] ( 32 ) HTML (1 KB)  PDF (649 KB)  ( 31 )

Copyright © Editorial Board of 中国当代医药 Supported by:Beijing Magtech