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Effect of taking Simethicone at different time points before colonoscopy on intestinal cleanliness and polyp detection rate |
ZHAI Chunying KE Xiaoli XU Yaohua CHENG Xiaohe QIU Yu |
Department of Gastroenterology,Beijing Puren Hospital,Beijing 100062,China |
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Abstract Objective To study the effect of taking Simethicone at different time points before colonoscopy on intestinal cleanliness and the detection rate of intestinal polyps.Methods The 200 patients who underwent colonoscopy in Beijing Puren Hospital from January 2020 to June were selected s vesearch objects,they were divided into group A,group B and group C according to the random number table method.Group A(n=70)took Simethicone 2 h before the colonoscopy,group B(n=65)took simethicone 1 h before the examination,and group C(n=65)took Simethicone 0.5 h before the examination.The differences in intestinal cleanliness,intestinal polyp detection rate and intestinal air bubbles before examination were compared among the three groups of patients.Results There was no statistically significant difference in the score of intestinal cleanliness of the three groups of patients(P>0.05).The comparison of the detection rate of intestinal polyps >0.5 cm and the total detection rate of intestinal polyps in the three groups of patients were not statistically significant(P>0.05).The detection rate of intestinal polyps ≤0.5 cm in group B was higher than that in group A and group C,the difference was statistically significant(P<0.05).The score of intestinal air bubbles in group B was higher than that in group A and group C,and the difference was statistically significant(P<0.05).Conclusion Taking Simethicone at different time points before colonoscopy has no effect on intestinal cleansing,but taking Simethicone 1 h before the examination can increase the detection rate of small polyps and more effectively inhibit the production of intestinal bubbles,which has positive value.
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