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Effect of Pregabalin + Escitalopram on pain degree and depression in patients with central neuralgia after stroke |
QI Qiongyao1 ZENG Duo2 LI Jun1 ZHENG Xiaodong1 YI Fei1 |
1.Department of Neurology,Pingxiang People's Hospital,Jiangxi Province,Pingxiang 337000,China;
2.Department of Neurosurgery,Pingxiang People's Hospital,Jiangxi Province,Pingxiang 337000,China |
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Abstract Objective To investigate the effect of Pregabalin + Escitalopram on pain degree and depression in patients with central neuralgia after stroke.Methods A total of 60 patients with central neuralgia after stroke treated in Pingxiang People's Hospital from July 2018 to July 2021 were selected as research subjects,and they were divided into control group(n=30)and observation group(n=30)by random number table method.The control group received conventional treatment,and the observation group treated with Pregabalin + Escitalopram.Visual analog scale(VAS),Hamilton depression scale(HAMD)and Hamilton anxiety scale(HAMA)scores were compared between the two groups.Results Before treatment,there were no significant differences in VAS,HAMA and HAMD scores between the two groups(P>0.05).After treatment,VAS,HAMA and HAMD scores in the two groups were lower than those before treatment,the differences were statistically significant(P<0.05).After treatment,VAS,HAMA and HAMD scores in observation group were lower than those in control group,the differences were statistically significant(P <0.05).Conclusion Pregabalin + Escitalopram have positive effect on the improvement of pain symptoms and depression in patients with central neuralgia after stroke.
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