Abstract Objective To compare the application effects of Tetracaine Mortar and Paraffin Oil in urinary catheter indwelling after male genitourinary system surgery.Methods A total of 83 patients with percutaneous nephrolithotomy under general anesthesia admitted to Operating Room of the 908th Hospital of China People's Liberation Army Joint Logistic Support Force from January 2017 to August 2021 were selected as the study subjects.According to the random number table method,the patients were divided into in the Tetracaine group(42 cases)and in the Paraffin Oil group(41 cases).The Tetracaine group was given Tetracaine Mortar for urinary catheter indwelling,and the Paraffin Oil group was given Paraffin Oil for urinary catheter indwelling.The hemodynamic changes at drug injection(T0)and at 5 min(T1),10 min(T2)and 30 min(T3)after removal of tracheal catheter,postoperative emergence agitation and comfort and urethral irritation response at 8,24 and 48 h after surgery were compared between the two groups of patients.Results The heart rate(HR)and mean arterial pressure(MAP)showed downward trends,while the blood oxygen saturation(SpO2)showed an upward trend in the Tetracaine group,but there were no obvious changes in HR and MAP and SpO2 showed an upward trend in the Paraffin Oil group.There were no statistical differences in the levels of HR,MAP and SpO2 between the two groups at T0(P＞0.05).The level of HR of the Tetracaine group at T1,T2 and T3 were slower than those of the paraffin oil group,and the level of MAP of the Tetracaine group at T1,T2 and T3 were lower than those of the Paraffin Oil group,the differences were statistically significant(P＜0.05).There were no statistical significances in the levels of SpO2 at T1,T2 and T3 between the two groups(P＞0.05).The postoperative emergence agitation score in the Tetracaine group was lower than that in the Paraffin Oil group,the difference was statistically significant(P＜0.05).The GCQ score of the two groups showed a gradually increasing trend,and the GCQ scores in the Tetracaine group at 12,24 and 48 h after surgery were higher than those in the Paraffin Oil group,the differences were statistically significant(P＜0.05).The incidence rate of urethral irritation response in the Tetracaine group was lower than that in the Paraffin Oil group,the difference was statistically significant(P＜0.05).Conclusion The application of Tetracaine Mortar in urinary catheter indwelling after male genitourinary system surgery is beneficial to stabilizing the heart rate and mean arterial pressure,relieving the postoperative emergence agitation,improving the postoperative comfort and reducing the urethral irritation of patients.
XIE Dan,ZHANG Xiaoling,LUO Lei, et al. Comparison of application effects of Tetracaine Mortar and Paraffin Oil in urinary catheter indwelling after percutaneous nephrolithotomy[J]. 中国当代医药, 2022, 29(10): 92-95.
