还原型谷胱甘肽在慢性肾衰竭患者中的应用效果

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (567 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the application effect of Reduced Glutathione in patients with chronic renal failure.Methods A total of 260 patients with chronic renal failure admitted to the Third People's Hospital of Fujian University of Traditional Chinese Medicine from January 2018 to January 2021 were selected as the research objects,and were divided into observation group(130 cases)and control group(130 cases)using the random number table method.The observation group was treated with conservative treatment combined with Reduced Glutathione,and the control group was treated with conservative treatment.The hemoglobin(Hb)and serum creatinine(Scr)levels of the two groups were compared.Results Before treatment,the Hb and Scr levels of the two groups were not statistically different(P＞0.05).After treatment,the Hb level of the observation group was higher than that of the control group,and the Scr level was lower than that of the control group,the differences were statistically significant(P＜0.05).After treatment,Hb level of patients with chronic kidney disease(CKD)stage 3,CKD stage 4 and CKD stage 5 in the observation group was higher than that in the control group,while Scr level was lower than that in the control group,the differences were statistically significant(P＜0.05).Conclusion Reduced Glutathione has a positive effect in the treatment of patients with chronic renal failure,it can effectively improve the renal function of patients,and is suitable for patients in different stages of disease progression such as CKD3,CKD4,and CKD5.It is worthy of promotion.

Key words： Chronic renal failure Reduced Glutathione Kidney function Stages of disease

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	PENG Ting
	PENG Weihua
	XU Minmin
	WEI Lifang

Cite this article:

PENG Ting,PENG Weihua,XU Minmin, et al. Curative effect of Reduced Glutathione in different stages of chronic renal failure[J]. 中国当代医药, 2022, 29(10): 20-23.

URL:

https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I10/20

[1]	Yuenyongchaiwat K，Namdang P，Vasinsarunkul P，et al.Effectiveness of inspiratory muscle training on respiratory fitness and breathlessness in chronic renal failure：A randomized control trial[J].Physiother Res Int，2021，26（1）：e1879.
[2]	Mroue A，Moujaess E，Kourie HR，et al.Exploring the knowledge gap of immune checkpoint inhibitors in chronic renal failure：A systematic review of the literature[J].Crit Rev Oncol Hematol，2021，157（22）：103-169.
[3]	Li H，Feng Y，Sun W，et al.Antioxidation，anti-inflammation and anti-fibrosis effect of phosphorylated polysaccharides from Pleurotus djamor mycelia on adenine-induced chronic renal failure mice[J].Int J Biol Macromol，2021，170（15）：652-663.
[4]	Patoulias D，Papadopoulos C，Stavropoulos K，et al.Metaanalysis of Dedicated Renal Outcome Trials Assessing the Cardio-renal Efficacy of Sodium-Glucose Co-transporter-2 Inhibitors in Patients With Chronic Kidney Disease and Albuminuria.[J]Am J Cardiol，2021，138（1）：116-118.
[5]	李波.还原型谷胱甘肽联合前列地尔治疗慢性肾功能不全疗效[J].中外医疗，2018，37（2）：105-107.
[6]	陈长云，罗小琴，任颖.肾衰宁片联合还原型谷胱甘肽治疗非终末期慢性肾衰竭临床研究[J].中国药业，2019，28（18）：62-64.
[7]	陈长云，罗小琴，任颖.肾衰宁片联合还原型谷胱甘肽治疗非终末期慢性肾衰竭临床研究[J].中国药业，2019，28（18）：62-64.
[8]	陈宏辉，陈莲，黄柳莹.还原型谷胱甘肽片治疗慢性结肠炎的临床疗效观察[J].中国药物经济学，2018，13（11）：82-84.
[9]	窦艳娜，宋冬岩，王春燕，等.尿血管紧张素原与肾脏间质炎性细胞浸润的相关性研究[J].中国全科医学，2018，21（33）：4082-4087.
[10]	邱双平，吴武忠.前列地尔联合还原型谷胱甘肽治疗慢性肾衰竭的临床研究[J].临床和实验医学杂志，2016，15（7）：654-656.
[11]	罗丽.前列地尔合还原型谷胱甘肽治疗早中期慢性肾衰竭疗效观察[J].实用中西医结合临床，2018，18（9）：75-76.
[12]	李娟，何娟，毛恩强，等.还原型谷胱甘肽对重症患者使用万古霉素致药物性肾损伤的保护作用[J].中华危重病急救医学，2020，32（7）：819-823.
[13]	王天义.肾康注射液联合还原型谷胱甘肽治疗慢性肾脏病疗效观察[J].安徽中医药大学学报，2018，37（3）：17-19.
[14]	叶婷婷，邓妍妍，王黎萍，等.还原型谷胱甘肽对慢性肾衰竭患者氧化应激的影响[J].贵州医药，2014（2）：123-124.
[15]	史春夏，贾姝婧，李忠心.杏丁注射液联合还原型谷胱甘肽治疗慢性肾衰竭的疗效观察[J].现代药物与临床，2017，32（10）：1963-1966.