消旋卡多曲辅助治疗急性腹泻患儿的效果分析

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摘要目的探讨消旋卡多曲治疗小儿急性腹泻的临床效果。方法选取2018年4〜10月收治于我院的96例急性腹泻患儿作为研究对象，按照随机数字表法将其分为对照组和实验组，每组48例。在常规治疗的基础上，对照组给予蒙脱石散及双歧杆菌四联活菌片治疗，实验组在对照组治疗的基础上给予消旋卡多曲治疗，疗程5〜7 d。治疗后，比较两组患儿的临床效果、治疗前后临床症状分级量化积分及临床症状改善情况。结果实验组患儿的临床治疗总有效率高于对照组，差异有统计学意义（P<0.05）。治疗前，两组患儿的临床症状分级量化积分比较，差异无统计学意义（P>0.05）；治疗后，两组患儿的临床症状分级量化积分低于治疗前，实验组患儿的食欲不振、大便次数、大便性状积分均低于对照组，差异有统计学意义（P<0.05）。实验组患儿的退热、呕吐停止、腹痛腹胀停止、大便次数恢复正常及大便性状恢复正常时间均短于对照组，差异有统计学意义（P<0.05）。结论消旋卡多曲辅助治疗小儿急性腹泻的效果明显，可有效改善患儿的临床症状并缩短治疗时间，值得临床推广应用。

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	黄转弟

关键词 ：消旋卡多曲, 急性腹泻, 临床疗效

Abstract：Objective To investigate the clinical effect of Racecadotril in the treatment of children with acute diarrhea.Methods Ninety-six children with acute diarrhea admitted to our hospital from April to October 2018 were selected as research objects and divided into control group and experimental group according to random number table method,48 cases in each group.On the basis of routine treatment,the control group was treated with Montmorillonite Powder and Bifidobacterium Quadruple Viable Tablets,while the experimental group was treated with Racecadotril on the basis of the control group for 5-7 days.After treatment,the clinical effects,clinical symptom grading and quantitative scores and clinical symptom improvement before and after treatment were compared between the two groups.Results The total effective rate of clinical treatment in the experimental group was higher than that in the control group,and the difference was statistically significant (P<0.05).Before treatment,there was no significant difference in clinical symptom grading and quantitative scores between the two groups (P>0.05).After treatment,the clinical symptom grading quantitative scores of the two groups of children were lower than those before treatment,and the anorexia,stool frequency and stool character scores of the experimental group were lower than those of the control group,with statistically significant differences (P<0.05).The fever reduction,vomiting cessation,abdominal pain and distension cessation,stool frequency return to normal and stool character return to normal time in the experimental group were shorter than those in the control group,the differences were statistically significant (P<0.05).Conclusion Racecadotril is effective in the treatment of children with acute diarrhea.which can effectively improve the clinical symptoms of children and shorten the treatment time,and is worthy of clinical promotion and application.

Key words： Racecadotrill Acute diarrhea Clinical efficacy

引用本文:

黄转弟. 消旋卡多曲辅助治疗急性腹泻患儿的效果分析[J]. 中国当代医药, 2020, 27(2): 142-144.
HUANG Zhuan-di. Effect analysis of Racecadotril in adjuvant treatment of children with acute diarrhea. 中国当代医药, 2020, 27(2): 142-144.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2020/V27/I2/142

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