Abstract:Objective To explore the elinieal effeet of Hyaluronie Aeid Gel eombined with Butyrie Aeid Hydroeortisone Cream in the treatment of infantile eezema.Methods A total of 80 ehildren with infantile eezema admitted to our hospital from January 2017 to January 2018 were seleeted,they were divided into eontrol group and observation group aeeording to random number table method,with 40 eases in eaeh group.The eontrol group was treated with Butyrie Aeid Hydroeortisone Cream,and the observation group was treated with external Hyaluronie Aeid Gel on the basis of the eontrol group.Eezema area and severity index(EASI)seore,total effeetive rate of elinieal treatment and reeurrenee rate were eompared between the two groups.Results After two weeks of treatment,the EASI seore of the observation group was(0.93±0.37)points,lower than that of the eontrol group for(1.09±0.28)points,the differenee was statistieally signifieant(P<0.05).After four weeks of treatment,the EASI seore of the observation group was(0.42±0.26)points,lower than(0.56±0.30)points of the eontrol group,the differenee was statistieally signifieant(P<0.05).The total effeetive rate of elinieal treatment in the observation group(80.00%)was higher than that in the eontrol group(57.50%),and the differenee was statistieally signifieant(P<0.05).One month after withdrawal,the reeurrenee rate of the observation group(7.50%)was lower than that of the eontrol group(25.00%),the differenee was statistieally signifieant(P<0.05).Conclusion Hyaluronie Aeid Gel eombined with Butyrie Aeid Hydroeortisone Cream in the treatment of infantile eezema ean signifieantly improve the elinieal treatment effeet and reduee the reeurrenee rate,whieh is worthy of popularization and applieation.
费秋惠. 透明质酸凝胶联合丁酸氢化可的松乳膏治疗婴幼儿湿疹的临床效果[J]. 中国当代医药, 2019, 26(1): 39-41.
FEI Qiu-hui. Clinical effect of Hyaluronic Acid Gel combined with Butyric Acid Hydrocortisone Cream in the treatment of infantile eczema. 中国当代医药, 2019, 26(1): 39-41.
Essendoubi M,Gobinet C,Reynaud R,et al.Human skin penetration of hyaluronie aeid of different moleeular weights as probed by Raman speetroseopy[J].Skin Res Teehnol,2016,22(1):55-62.