Abstract：Objective To investigate the efficacy and safety of combined interventions included dopamine by pumping in prevention of intradialytic hypotension in critically ill patients.Methods 21 patients of critically ill patients in our hospital from January 2010 to December 2015 received totally 167 times of hemodialysis with dopamine by pumping，colloid solution infusion in advance，lower dialysate temperature，sodium profile，ultrafiltration Profile and higher calcium dialysate.Results 85.7%could complete hemodialysis safely in above 2 hours，severe adverse reactions was only 3.6%. Conclusion The combined interventions including dopamine by pumping can effectively and safely prevent intradialytic hypotension in critically ill patients.
Kuipers J，Oosterhuis JK，Krijnen WP，et al.Prevalence of intradialytic hypotension，clinical symptoms and nursing interventions——a three-months，prospective study of 3818 haemodialysis sessions［J］.BMC Nephrol，2016，27（17）：21.
［4］
Ettema EM，Zittema D，Kuipers J，etal.Dialysishypotension：a role for inadequate increase in arginine vasopressin levels？A systematic literature review and meta-analysis［J］. Am JNephrol，2014，39（2）：100-109.
［5］
Mo Y，Liu X，Qin X，et al.Shenfu injection for intradialytic hypotension：a systematic review and meta-analysis［J］.Evid Based Complement AlternatMed，2014，2014：279853.
［6］
Saxena A，Sharma RK，Gupta A，et al.Non-invasive method for preventing intradialytic hypotension：a pilot study［J］. Saudi JKidney Dis Transpl，2015，26（5）：896-905.
［7］
RazeghiE，Dashti-KhavidakiS，Nassiri S，etal.A randomized crossover clinical trial of sertraline for intradialytic hypotension［J］.Iran JKidney Dis，2015，9（4）：323-330.
Leung KC，Quinn RR，Ravani P，et al.Ultrafiltration biofeedback guided by blood volume monitoring to reduce intradialy tic hypotensive episodes in hemodialysis：study protocol for a randomized controlled trial［J］.Trials，2014，10 （15）：483-491.
［12］
Zbroch E，Koc-Zorawska E，Malyszko J，et al.Circulating levels of renalase，norepinephrine，and dopamine in dialysis patients［J］.Ren Fail，2013，35（5）：673-679.
［13］
Nesrallah GE，Suri RS，Guyatt G，et al.Biofeedback dialysis for hypotension and hypervolemia：a systematic review and meta-analysis［J］.Nephrol Dial Transplant，2013，28（1）：182-191.
［14］
du Cheyron D，Terzi N，Seguin A，et al.Use of online blood volume and blood temperature monitoring during haemodialysis in critically ill patients with acute kidney injury：a single-centre randomized controlled trial［J］. Nephrol Dial Transplant，2013，28（2）：430-437.
［15］
Gil HW，Bang K，Lee SY，et al.Efficacy of hemocontrol biofeedback system in intradialytic hypotension-prone hemodialysis patients［J］.J Korean Med Sci，2014，29（6）：805-810.
Tsai MY，Su YJ，Ng HY，et al.Study protocol for a singleblind，placebo-controlled randomised trial of Tianjiu effects in patients with intradialytic hypotension［J］.BMJ Open，2016，6（3）：e009976.
京公网安备 11010502046607号