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Quick Search     Adv Search 2024 Vol. 31, No. 15 Published: 2024-05-28   4 Application effect of acupuncture combined with the synovitis prescription of the Southern Shaolin School in the treatment of dampness-heat arthralgia type knee osteoarthritis WU Tianlin1 WANG Weijia1 ZHOU Tengxiang1 LIN Qiaoxuan1 LIU Qiaobao2 LI Changning1 NIU Susheng3 Objective To observe the effect of acupuncture combined with synovitis prescription of the Southern Shaolin School in the treatment of dampness-heat arthralgia type knee osteoarthritis.Methods A total of 60 patients with dampness-heat arthralgia type knee osteoarthritis admitted to the Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine from May 2021 to May 2022 were selected as the study objects,and they were divided into control group and observation group according to random number table method,with 30 cases in each group.The control group was given oral Celecoxib Capsules,and the observation group was given acupuncture treatment combined with oral synovitis prescription of the Southern Shaolin School.The course of treatment was 4 weeks.The corresponding indexes of the two groups were observed before and after treatment,and the knee swelling degree,knee swelling improvement rate,the Western Ontario and McMaster Universities (WOMAC)scores were calculated.Results After treatment,the knee swelling degree and WOMAC score in the observation group were lower than those in the control group,and the knee swelling improvement rate was higher than that in the control group,with statistical significances (P＜0.05).Conclusion Acupuncture combined with the synovitis prescription of the Southern Shaolin School is effective in the treatment of dampness-heat arthralgia type knee osteoarthritis,which can effectively reduce knee swelling pain and improve knee movement function. 2024 Vol. 31 (15): 4-08 [Abstract] ( 16 ) HTML (1 KB)  PDF (663 KB)  ( 43 ) 9 Study on thin layer chromatography identification of compound Sanhuang Gel GAN Canyun YU Jin CHEN Haihong NI Tianyu YANG Haiyan Objective To establish the thin layer chromatography (TLC) method for identification of compound Sanhuang Gel.Methods The TLC was used to investigate the influence of different developing agent,different temperature and different thin layer plate manufacturers on the identification of rhubarb,scutellaria and phellodendron in compound Sanhuang Gel,and to determine the best TLC conditions.Results The rhubarb was made of silica gel H thin layer plate with toluene-ethyl acetate-formic acid(7∶3∶0.1)as the development agent,removed,dried,examined under 365 nm UV lamp,the spots showed clear color.Polyamide film was used in scutellaria baicalensis,and toluene-ethyl acethane-methanol-formic acid (10∶3∶1∶2)was used as development agent,removed,dried,examined under 365 nm UV lamp,and fumed in ammonia vapor,the spots showed clear color.The silica gel G thin layer plate was used and toluene-methanol-ethyl-acetate-isopropyl-alcohol-concentrated ammonia test solution(6∶1.5∶3∶1.5∶0.5)was used as the development agent,removel,dried,and examined under 365 nm ultraviolet lamp,the spots showed clear color.The TLC of the three drugs showed obvious characteristics,good separation and no negative interference.Conclusion The TCL method is specific and durable,which can be used for the quality control of compound Sanhuang Gel. 2024 Vol. 31 (15): 9-13 [Abstract] ( 18 ) HTML (1 KB)  PDF (1816 KB)  ( 83 ) 14 Predictive efficacy of combined detection of α1 antitrypsin,D-dimer and homocysteine on pregnancy outcome in patients with threatened abortion CHEN Bo Objective To investigate the predictive efficacy of combined detection of α1-antitrypsin (AAT),D-dimer(D-D) and homocysteine (Hcy) on pregnancy outcome in patients with threatened abortion.Methods The clinical data of 100 patients with threatened abortion who received tocolysis treatment in Pingxiang People's Hospital from June 2021 to January 2023 were retrospectively analyzed.According to the pregnancy outcome,they were divided into tocolysis failure group and tocolysis success group.The baseline data,serum AAT,D-D and Hcy levels in early pregnancy were compared between the two groups.Logistic regression analysis was used to explore the relationship between serum AAT,D-D and Hcy levels and pregnancy outcome in patients with threatened abortion.The ROC curve was used to analyze the predictive efficacy of serum AAT,D-D and Hcy levels on pregnancy outcome in patients with threatened abortion.Results Among the 100 patients with threatened abortion,20 cases (20.00%)had inevitable abortion and 15 cases (15.00%)had delayed abortion after tocolytic therapy,which were included in the tocolysis failure group,65 cases (65.00%)continued pregnancy to successful delivery and were included in the tocolysis success group.The level of serum AAT in the tocolysis failure group was lower than that in the tocolysis success group before the treatment,and the levels of D-D and Hcy were higher than those in the tocolysis success group,and the differences were statistically significant (P＜0.05).Logistic regression analysis showed that higher serum AAT (β=-1.769,OR=0.170,95%CI=0.068-0.429) was a independent protective factor for pregnancy outcome in patients with threatened abortion,and higher D-D (β=2.504,OR=12.229,95%CI=4.037-37.045) and Hcy(β=0.612,OR=1.844,95%CI=1.212-2.804) were independent risk factors for pregnancy outcome in patients with threatened abortion(P＜0.05).The ROC curve showed that serum AAT,D-D and Hcy levels could be used to predict the pregnancy outcome of patients with threatened abortion.The combined prediction of the three had the highest prediction efficiency,and the AUC was 0.898,the sensitivity and specificity were 88.57% and 78.46%,respectively.Conclusion The levels of serum AAT,D-D and Hcy are related to the pregnancy outcome of patients with threatened abortion.If there is low expression of AAT,high expression of D-D and Hcy in clinical practice,threatened abortion should be alerted. 2024 Vol. 31 (15): 14-17转23 [Abstract] ( 16 ) HTML (1 KB)  PDF (795 KB)  ( 85 ) 18 Research on quality standard of Tiangui Congying Granules WANG Shanshan1 ZHANG Zhe1 XIA Zhongting1 ZHANG Min2 HU Kaiyong2 LIU Jun3 LI Yanying3 HUANG Nengting3 Objective To establish the quality standard of Tiangui Congying Granules.Methods Cistanche deserticola,lily,artemisia anomala and fruit of glossy privet in Tiangui Congying Granules were identified by thin layer chromatography(TLC).High performance liquid chromatography-diode-array detector (HPLC-DAD)was used to simultaneously determine the contents of echinacin and ligustrin.Acetonitrile -0.1% phosphoric acid as mobile phase for gradient elution,and the detection wavelength were 330 nm(echinacea)and 224 nm(ligustrin)respectively.And the column temperature was 35℃.Injection volume was 10 μl.Results The spots in TLC identification chromatogram were clear,the resolution was good,and the negative chromatogram had no interference.The linear relationship between the injection volume and the peak area of echinacin was good between 0.104 0 μg and 2.600 μg(r=0.999 9).The linear relationship between the injection volume and the peak area of ligustroside was good between 0.122 6 μg and 3.065 0 μg(r=1.000 0).Echinacin and ligustrin of the average sample recovery were 97.52% and 104.44% respectively,the RSD were less than 3.0%.Conclusion The established quality standard method has strong specificity,good stability,high accuracy and good durability,and it is used for the quality control of Tiangui Congying Granules. 2024 Vol. 31 (15): 18-23 [Abstract] ( 17 ) HTML (1 KB)  PDF (1100 KB)  ( 26 ) 24 Clinical efficacy of Tenofovir Amibufenamide in the treatment of patients with chronic hepatitis B ZHOU Hongyan1 GUO Ting1 LI Qingqi2 YI Xulan3 WANG Feng4 LAI Qin5 Objective To investigate the clinical effect of Tenofovir Amibufenamide(TMF)in the treatment of chronic hepatitis B (CHB).Methods A total of 120 CHB patients admitted to the Second Affiliated Hospital of Yichun University from May to October 2022 were selected as the study objects.According to their treatment experience,the patients were divided into initial CHB group(n=38)and retreated CHB group(n=82),and both groups were treated with TMF.The virological response of the two groups of patients was compared,and the proportion of alanine transaminase(ALT)returned to normal was counted in all patients,and the changes of creatinine(Cr),total cholesterol (TC),triglyceride(TG),serum cystatin C (CysC)and estimated glomerular filtration rate(eGFR)were observed.Results The hepatitis B virus DNA(HBV DNA)level of the two groups after 12 and 24 weeks of treatment was lower than those before treatment,and the proportion of complete virological response of the initial CHB group at 24 weeks of treatment was higher than that at 12 weeks of treatment,the differences were statistically significant(P＜0.05).Complete virological response was achieved in 40 patients with retreated CHB before TMF treatment,and the proportion of complete virological response in the remaining 42 patients after 12 and 24 weeks of treatment was not statistically significant(P＞0.05).The proportion of ALT returning to normal was 40.00%at 12 weeks and 78.33%at 24 weeks.There were no significant differences in the levels of Cr,TC,TG,CysC and eGFR of all patients after 24 weeks of treatment and before treatment (P＞0.05).Conclusion TMF treatment of CHB patients has a good early effect,patients with renal function and lipid indexes have no adverse safety effects,but the long-term effect remains to be seen. 2024 Vol. 31 (15): 24-27 [Abstract] ( 19 ) HTML (1 KB)  PDF (487 KB)  ( 10 ) 28 Investigation of sleep structure in children with snoring and analysis of its influencing factors WANG Bing HU Shuihua Objective To analyze the investigation of sleep structure and its influencing factors in children with snoring,and to provide reference for clinic.Methods A total of 160 children with snoring treated in the Second Affiliated Hospital of Nanchang University from April 2022 to April 2023 were selected as the study objects,and they were divided into abnormal sleep structure group and non-abnormal sleep structure group according to whether they had abnormal sleep structure.General clinical data of two groups of children were collected to analyze the influencing factors of abnormal sleep structure in children with snoring.Results The results of univariate analysis showed that the abnormal sleep structure in children with snoring was related to weight,electronic screen use time,outdoor activity time,anxiety,depression and parental education level,and the differences were statistically significant(P＜0.05).Multivariate analysis of logistic regression model showed that weight(β=0.304,OR=1.356,95%CI=1.030-1.786),screen time＞1 h(β=0.835,OR=2.304,95%CI=1.206-4.404),outdoor activity time≤2 h (β=1.083,OR=2.955,95%CI=1.243-7.025),anxiety (β=0.693,OR=1.999,95%CI=1.058-3.776),depression(β=0.708,OR=2.030,95%CI=1.074-3.838)and high school or below parental education (β=0.738,OR=2.092,95%CI=1.106-3.957)were independent risk factors for abnormal sleep structure in children with snoring (P＜0.05).Conclusion The incidence of abnormal sleep structure is higher in children with snoring,and there are many independent risk factors for abnormal sleep structure,among which heavier body weight,screen time ＞1 h,outdoor activity time ≤2 h,anxiety,depression and low parental education are independent risk factors for abnormal sleep structure in children with snoring. 2024 Vol. 31 (15): 28-31 [Abstract] ( 18 ) HTML (1 KB)  PDF (505 KB)  ( 23 ) 32 Effect of vitamin B1 combined with enteral nutrition in the treatment of severe stroke WU Siping LIN Taiyu Objective To investigate the clinical effect of vitamin B1 combined with enteral nutrition in the treatment of severe stroke.Methods A total of 80 patients with severe stroke admitted to Pingxiang People's Hospital from January 2022 to October 2023 were selected as the study objects,they were divided into study group and control group according to random number table method,with 40 patients in each group.The control group was treated with enteral nutrition,and the study group was treated with vitamin B1.Nutritional indexes(total protein[TP],hemoglobin[Hb],albumin[ALB]),immunoglobulin(Ig)A,IgG,IgM,and prognosis were compared between the two groups before and after treatment.Results After treatment,the levels of TP and Hb in the two groups were higher than those before treatment,and the levels of TP and Hb in the study group were lower than those in the control group,the differences were statistically significant (P＜0.05).After treatment,MDA and SOD levels in the study group were lower than those in the control group,and the differences were statistically significant (P＜0.05).After treatment,the levels of IgA,IgG and IgM in the two groups were lower than those before treatment,and the levels of IgA,IgG and IgM in the study group were lower than those in the control group,with statistical significances(P＜0.05).The proportion of good prognosis in the study group(47.50%)was higher than that in the control group(15.00%),and the difference was statistically significant (P＜0.05).Conclusion The combination of vitamin B1 and enteral nutrition has shown potential benefits in the treatment of severe stroke and may promote patient recovery by improving nutritional indicators and enhancing immune response. 2024 Vol. 31 (15): 32-35 [Abstract] ( 18 ) HTML (1 KB)  PDF (497 KB)  ( 24 ) 36 Effect of Clozapine combined with Risperidone on the levels of inflammatory factors and positive and negative syndrome scale scores in patients with schizophrenia YUAN Aiping YANG Zhou LIU Chang Objective To investigate the effects of Clozapine combined with Risperidone on serum inflammatory factor levels and positive and negative symptom scale(PANSS)scores in patients with schizophrenia(SZ),in order to guide the formulation of clinical treatment measures and promote clinical benefit in patients with SZ.Methods A total of 80 SZ patients admitted to Jiangxi Honorary Military Preferential Treatment Hospital from January 2020 to August 2022 were selected as the study objects,and they were divided into control group(treated with Clozapine)and observation group(treated with Clozapine combined with Risperidone)according to random number table method,with 40 cases in each group.The therapeutic effect,PANSS score and serum inflammatory factor levels were compared between the two groups.Results The total effective rate of observation group was higher than that of control group,and the difference was statistically significant(P＜0.05).After treatment,the level of serum interleukin-13 in observation group was higher than that in control group,and the level of negative symptoms,positive symptoms,general psychiatric score,total score of PANSS and serum tumor necrosis factor-α were lower than that in control group,and the differences were statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse drug reactions between the two groups(P＞0.05).Conclusion Risperidone combined with Clozapine has a significant effect on SZ,which can effectively reduce PANSS score and regulate the level of inflammatory factors. 2024 Vol. 31 (15): 36-39 [Abstract] ( 17 ) HTML (1 KB)  PDF (399 KB)  ( 23 ) 40 Research on the analysis of factors influencing suicidal behavior in depression ZHAO Xianxian1 WANG Yan2 TIAN Jing2 ZHOU Cong3 CUI Jian2▲ Objective To explore the factors influencing suicidal behaviors in patients with depression.Methods A total of 125 patients with depression who had not been treated by the drug system in Shandong Daizhuang Hospital from October 2021 to December 2022 were retrospectively selected as the study objects,and divided into depression suicidal behavior group(55 cases)and depression without suicidal behavior group(70 cases)according to whether they were accompanied by suicidal behavior.Blood platelet count,platelet distribution width,mean platelet volume and platelet pressure were measured by blood analyzer to analyze the influencing factors of depression accompanied by suicidal behavior.Results There were statistically significant differences in platelet count,mean platelet volume and platelet distribution width between the two groups (P＜0.05).The results of multivariate analysis suggested that mean platelet volume (β=-0.48,OR=0.62,95%CI=0.39-0.98)was a protective factor affecting the occurrence of suicidal behavior in depression (P＜0.05).Conclusion The mean platelet volume is closely related to the occurrence of suicidal behaviors in depression.This finding could provide a potential biomarker for the clinical prediction of suicide risk in patients with depression. 2024 Vol. 31 (15): 40-43 [Abstract] ( 17 ) HTML (1 KB)  PDF (625 KB)  ( 28 ) 44 Effect of stellate ganglion block combined with electroacupuncture on cervico-facial postherpetic neuralgia FU Xianglong Objective To investigate the clinical effect of stellate ganglion block+electroacupuncture in patients with cervico-facial postherpetic neuralgia.Methods A total of fifty-two patients with cervix and facial postherpetic neuralgia admitted to Zaozhuang Dermatology and Venereal Disease Prevention and Control Hospital from January 2020 to November 2022 were selected as the study objects,and they were divided into the reference group(26 cases)and the study group(26 cases)according to random number table method.The reference group was treated with stellate ganglion block,and the study group was treated with stellate ganglion block combined with electroacupuncture.The total effective rate,dysfunction score before and after treatment,pain degree score,treatment satisfaction score and adverse reactions were compared between the two groups.Results The total effective rate of the study group was higher than that of the reference group,and the difference was statistically significant (P＜0.05).Before treatment,there was no significant difference in functional impairment score between the two groups(P＞0.05).After treatment,the dysfunction score of the study group was lower than that of the reference group,and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in pain severity score between the two groups (P＞0.05).After treatment,the pain degree score of the study group was lower than that of the reference group,the difference was statistically significant (P＜0.05).Treatment method score,treatment detail score and treatment effect score of the study group were higher than those of the reference group,and the differences were statistically significant (P＜0.05).No obvious adverse reactions occurred in both groups.Conclusion After using stellate ganglion block and electroacupuncture to treat patients with postherpetic neuralgia in the neck and face,the treatment effect can be significantly improved.At the same time,the functional impairment and pain level of patients can be improved,and the satisfaction with treatment can be significantly enhanced,promoting a good prognosis for patients with postherpetic neuralgia in the neck and face. 2024 Vol. 31 (15): 44-47 [Abstract] ( 16 ) HTML (1 KB)  PDF (379 KB)  ( 33 ) 48 Durvalumab combined with Etoposide Capsules in the treatment of recurrent extensive small cell lung cancer PENG Liming Objective To investigate the efficacy of Duvalizumab combined with Etoposide Capsules in the treatment of recurrent extensive small cell lung cancer.Methods A total of forty patients with recurrent extensive small cell lung cancer admitted to Yichun People's Hospital from January 2021 to December 2022 were selected as the study subjects.They were divided into control group and observation group by random number table method,with 20 cases in each group.The control group patients were treated with Etoposide Capsules,while the observation group patients were treated with Duvalizumab combined with Etoposide Capsules.The clinical efficacy,changes in serum neuron-specific enolase(NSE)levels before and after chemotherapy,adverse reactions during treatment and long-term survival were compared between the two groups.Results The objective response rate and disease control rate of the observation group were higher than those of the control group,with statistically significant differences (P＜0.05).The serum NSE level in the observation group after chemotherapy was lower than that in the control group,with statistically significant difference(P＜0.05).There were no statistically significant differences in the incidence and severity of adverse reactions such as leukopenia,thrombocytopenia,neutropenia,gastrointestinal reactions,liver and kidney damage between the two groups during the treatment period(P＞0.05).The observation group had longer progression free survival and overall survival compared to the control group,with statistically significant difference (P＜0.05).Conclusion The combination of Duvalizumab and Etoposide Capsules has a significantly improved therapeutic effect on recurrent extensive small cell lung cancer compared to the use of Etoposide Capsules alone.It can significantly prolong the survival time of patients without significantly increasing adverse reactions,and is worthy of clinical recommendation. 2024 Vol. 31 (15): 48-51 [Abstract] ( 17 ) HTML (1 KB)  PDF (429 KB)  ( 14 ) 52 Predictive value of protein induced by vitamin K absence or antagonist Ⅱfor recurrence after transcatheter arterial chemoembolization combined with radiofrequency ablation for hepatitis B-related hepatocellular carcinoma LIU Xunqi1 CAI Yuan2 WANG Ying2 HUANG Xiangrong3▲ Objective To analyze the predictive value of protein induced by vitamin K absence or antagonist Ⅱ(PIVKA-Ⅱ)in recurrence of hepatitis B related hepatocellular carcinoma after transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation (RFA).Methods From June 2014 to November 2019,99 patients with hepatitis B surface antigen (HBsAg)positive hepatocellular cancer in the Third People's Hospital of Shenzhen were collected,and all patients were treated with TACE combined with RFA.Patients should be followed up for at least 2 years to observe recurrence.The optimal cut-off value of PIVKA-Ⅱprediction of recurrence was analyzed according to ROC curve,and the Kaplan-Meier method was used to plot the relationship between PIVKA-Ⅱand tumor recurrence,and Cox regression was analyzed to affect the independent risk factors for recurrence.Results The follow-up time was 11-104.7 months,and the median follow-up time was 36.9 months.By the end of follow-up,72 of 99 patients had recurrence,with a recurrence rate of 72.7%.ROC curve analysis determined that the optimal cut-off value of PIVKA-Ⅱfor predicting recurrence was 43.6 mAu/ml,sensitivity was 68.1%,specificity was 70.4%,Youden index was 0.385,and area under ROC curve was 0.66.The cut-off value of PIVKA-Ⅱwas 43.6 mAu/ml,and the high level group (57 cases) was≥43.6 mAu/ml.The low level group (42 cases)was＜43.6 mAu/ml.The cumulative recurrence rates at 1,3 and 5 years were 42%,81%and 87%in the high level group and 35%,53%and 80%in the low level group,respectively,and the differences were statistically significant (P＜0.05).Univariate analysis showed that the number of tumors,maximum tumor diameter,clinical stage,alpha fetoprotein (AFP),PIVKA-Ⅱwere associated with tumor recurrence(P＜0.05).Cox regression analysis showed that the number of tumors and PIVKA-Ⅱwere independent risk factors for recurrence of hepatitis B related hepatocellular carcinoma after treatment (P＜0.05).Conclusion PIVKA-Ⅱhas a certain predictive value for the recurrence of hepatitis B related hepatocellular carcinoma after treatment. 2024 Vol. 31 (15): 52-56 [Abstract] ( 15 ) HTML (1 KB)  PDF (522 KB)  ( 6 ) 57 Effect of Montelukast Sodium combined with interferon aerosol inhalation on immune function and inflammatory factors in school-age children with pneumonia HUANG Xiuhong CHEN Genji▲ Objective To explore the effect of Montelukast Sodium combined with interferon aerosol inhalation on immune function and levels of inflammatory factors in school-age children with pneumonia.Methods A total of 80 school-age children with pneumonia admitted to the Fifth Hospital of Xiamen from June 2022 to June 2023 were selected as the study objects,and they were divided into control group (40 cases) and observation group (40 cases) according to the random number table method.The children in the control group were treated with Montelukast Sodium,and the children in observation group were given Montelukast Sodium combined with interferon aerosol inhalation.The changes in immune function cluster of differentiation (CD3+、CD4+、CD8+),serum inflammatory factors (hypersensitive C-reactive protein[hs-CRP],procalcitonin [PCT],interleukin-6 [IL-6],interleukin-2 [IL-2])and oxidative stress (superoxide dismutase[SOD],total antioxidant capacity [T-AOC],advanced oxidative protein products [AOPPs],lipid hydroperoxide [LHP]) were observed and compared between both groups before treatment and after 2 weeks of treatment.The difference in disease condition (pneumonia severity index [PSI])was compared between the two groups after 2 weeks of treatment.Results The levels of CD3+and CD4+after 2 weeks of treatment in observation group were higher than those of the control group,while the level of CD8+was lower than that of the control group,and the differences were statistically significant(P＜0.05).After 2 weeks of treatment,the level of IL-2 in observation group was higher than that of the control group,while the levels of hs-CRP,PCT and IL-6 of the observation group were lower than those of the control group,with statistical differences (P＜0.05).After 2 weeks of treatment,the levels of SOD and T-AOC in the observation group were higher than those of the control group,while AOPPs and LHP of the observation group were lower than those in the control group,with statistically significant differences (P＜0.05).After 2 weeks of treatment,the PSI grading in the observation group was lower than that in control group,with a statistical significance (P＜0.05).Conclusion Montelukast Sodium combined with interferon aerosol inhalation can help to enhance the immune function and antioxidant capacity,and improve the disease condition,inflammatory status and tissue oxidative damage in school-age children with pneumonia. 2024 Vol. 31 (15): 57-60 [Abstract] ( 19 ) HTML (1 KB)  PDF (442 KB)  ( 30 ) 61 Effect of Lanqin Oral Liquid combined with Ribavirin Aerosol on the recovery time of symptoms and the rate of virus negativity in children with hand,foot and mouth disease LIU Feng CAI Bo LI Baodong WANG Ke Objective To explore the effect of Lanqin Oral Liquid combined with Ribavirin Aerosol on the recovery time of symptoms and the rate of virus seroconversion in children with hand,foot and mouth disease.Methods A total of 96 children with hand,foot,and mouth disease admitted to the Second People's Hospital of Liaocheng from July 2020 to June 2023 were selected as the study objects and they were divided into a control group(48 cases)and observation group(48 cases)according to random number table method.The control group was treated with Ribavirin Aerosol,while the observation group was treated with Lanqin Oral Liquid on the basis of the control group.Both groups were treated for 2 weeks.The clinical efficacy,symptom recovery time,serum immunoglobulin levels,and virus seroconversion rate between two groups were compared.Results The total clinical effective rate of the observation group was higher than that of the control group,and the symptom recovery time and hospital stay were shorter than those of the control group,and after treatment,the levels of immunoglobulin M (IgM),immunoglobulin G (IgG),and immunoglobulin A (IgA)in the observation group were higher than those in the control group,and the conversion rates of enterovirus and human enterovirus 71 (EV71)virus in the observation group were higher than those in the control group,and the differences were statistically significant（P＜0.05）.Conclusion Treatment with Lanqin Oral Liquid on the basis of Lufovirin Aerosol can significantly enhance clinical efficacy,quickly alleviate clinical symptoms,improve immunoglobulin levels,and increase the rate of virus seroconversion. 2024 Vol. 31 (15): 61-64 [Abstract] ( 17 ) HTML (1 KB)  PDF (460 KB)  ( 60 ) 65 Application value of two-dimensional shear wave elastography in the evaluation of intestinal fibrosis in Crohn's disease KE Pei CAO Ying▲ GAO Jun Objective To investigate the application value of two-dimensional shear wave elastography (2D-SWE)in the evaluation of intestinal fibrosis in Crohn's disease (CD).Methods A total of 68 CD patients admitted to Jiujiang Hospital of Traditional Chinese Medicine from August 2021 to March 2023 were selected as the study group,and 60 volunteers who underwent physical examination in Jiujiang Hospital of Traditional Chinese Medicine during the same period were selected as the control group.All patients underwent 2D-SWE examination,and the CD activity index (CDAI)was scored in the study group.Patients with CDAI score≥150 were included in the active group (18 cases),and those with CDAI score＜150 were included in the remission group(50 cases).The thickness of full-thickness and submucosal layer,standard deviation(SD)of elastic modulus and simple endoscopic score for CD (SES-CD)were compared among the three groups.The correlation between SES-CD and CDAI was analyzed.Results The full-thickness and submucosal thickness of the intestinal wall in the active group and the remission group were larger than those in the control group,and the full-thickness and submucosal thickness of the intestinal wall in the active group were larger than those in the remission group,and the SD measurement value,CDAI score,and SES-CD score were higher than those in the remission group,and the differences were statistically significant (P＜0.05).Spearman correlation analysis showed that CDAI was positively correlated with SES-CD scores in both active group and remission group(r=0.268,0.241,P＜0.05).Conclusion 2D-SWE is helpful to evaluate the activity of CD,clarify the changes of intestinal wall thickness,and provide a reliable reference for clinical diagnosis and treatment,which is worthy of promotion and application. 2024 Vol. 31 (15): 65-68 [Abstract] ( 19 ) HTML (1 KB)  PDF (422 KB)  ( 2 ) 69 Relationship between vaginal ultrasound measurement of uterine scar thickness and maternal and infant outcomes of scarred pregnancy patients LIAO Huifang1 HUANG Shuhua2 Objective To explore the relationship between vaginal ultrasound measurement of uterine scar thickness and maternal and infant outcomes of scar pregnancy patients.Methods A total of 72 pregnant women with cicatric uterus admitted to the First Affiliated Hospital of Gannan Medical College(Nankang Branch)from April 2020 to April 2022 were selected.All of them underwent vaginal ultrasound examination after admission,and they were divided into observation group(31 cases with cicatric thickness＜3 mm)and control group(41 cases with cicatric thickness≥3 mm)according to the thickness of cicatric uterus.Delivery and maternal and infant outcomes of the two groups were recorded,and Pearson or Spearman method was used to analyze the correlation between uterine scar thickness and maternal and infant outcomes of scar pregnancy patients.Results The vaginal delivery rate of the observation group (19.35%)was lower than that of the control group(60.98%),and the cesarean section rate (80.65%)was higher than that of the control group (39.02%),and the differences were statistically significant (P＜0.05).The Apgar scores of newborns in the observation group were lower than those in the control group at 1 min and 10 min after birth,and the incidence of fetal distress,uterine rupture and postpartum hemorrhage 24 h after delivery were higher than those in the control group,and the differences were statistically significant (P＜0.05).The uterine scar thickness was positively correlated with the Apgar scores of newborns at 1 and 10 minutes after birth(r=0.583,0.541,P＜0.05),and negatively correlated with fetal distress,uterine rupture,and postpartum hemorrhage 24 hours after birth (r=-0.394,-0.411,-0.571,P＜0.05).Conclusion The uterine scar thickness is positively correlated with the Apgar score of newborns at 1 and 10 minutes after birth,and negatively correlated with fetal distress,uterine rupture,and postpartum bleeding volume 24 hours.It is closely related to the maternal and infant outcomes of scar pregnancy patients,which has important clinical guiding significance. 2024 Vol. 31 (15): 69-72 [Abstract] ( 17 ) HTML (1 KB)  PDF (448 KB)  ( 2 ) 73 Effect of Chaihu plus Longgu Oyster Decoction combined with scraping therapy on subthreshold depression after percutaneous coronary intervention WANG Kepeng1 XU Xiafei2 Objective To investigate the effect of Chaihu plus Longgu Oyster Decoction combined with scraping therapy on subthreshold depression after percutaneous coronary intervention.Methods A total of 120 patients with subthreshold depression after percutaneous coronary intervention in Zaozhuang Hospital of Traditional Chinese Medicine from November 2021 to April 2023 were selected as the study objects,and they were divided into reference group (n=60)and study group(n=60) by random number table method.Patients in the reference group were treated with standard treatment and lifestyle adjustment treatment,while patients in the study group were treated with Chaihu plus Longgu Oyster Decoction combined with scraping therapy on the basis of the reference group.The Hamilton depression scale (HAMD),total effective rate of treatment and traditional Chinese medicine syndrome scores (insomnia score,hypochondriac score,nausea score,headache score,fatigue score and loss of appetite score)were compared between the two groups.Results Before treatment,there was no statistically significant difference in HAMD score between the two groups (P＞0.05).The HAMD scores of the study group were lower than those of the reference group at 7,14 and 28 days after treatment,and the differences were statistically significant (P＜0.05).The total effective rate of the study group was higher than that of the reference group,and the difference was statistically significant (P＜0.05).Before treatment,there were no statistically significant differences in the scores of insomnia,flank pain,nausea,headache,fatigue,and loss of appetite between the two groups (P＞0.05).After treatment,the above scores of the study group were lower than those of the reference group,and the differences were statistically significant (P＜0.05).Conclusion The oral administration of Chaihu plus Longgu Oyster Decoction+scraping therapy for patients with subthreshold depression after percutaneous coronary intervention has obvious effects on promoting the alleviation of depression degree,improving curative effect and improving traditional Chinese medicine syndromes,which can promote the good prognosis of patients with subthreshold depression after percutaneous coronary intervention. 2024 Vol. 31 (15): 73-76 [Abstract] ( 20 ) HTML (1 KB)  PDF (537 KB)  ( 0 ) 77 Effect of Zuozhi Liujun Decoction in the treatment of Helicobacter pylori positive chronic gastritis of liver-stomach disharmony type FU Bin WAN Jun FAN Shu ZHOU Weihong BAO Qichang CHEN Jianzhang LYU Yanhong HONG Jianxun Objective To explore the effect of Zuozhi Liujun Decoction in the treatment of Helicobacter pylori(Hp)positive chronic gastritis of liver-stomach disharmony type.Methods From January 2021 to December 2022,a total of 70 patients with chronic gastritis (Hp positive of liver-stomach disharmony type) admitted to Affiliated Hospital of Jiangxi College of Traditional Chinese Medicine(Fuzhou Hospital of Traditional Chinese Medicine)were selected as the research objects.According to the random number table method,they were divided into observation group(35 cases)and control group(35 cases).The observation group was treated with conventional western medicine quadruple therapy+Zuozhi Liujun Decoction,while the control group was treated with conventional western medicine quadruple therapy.The clinical efficacy,traditional Chinese medicine syndrome score,Hp eradication and recurrence rate,and serum biochemical indexes were compared between the two groups.Results The total effective rate (97.15%)and Hp eradication rate (94.28%)of the observation group were higher than those of the control group(82.85%,77.14%),and the Hp recurrence rate(2.86%)was lower than that of the control group(17.14%),and the differences were statistically significant(P＜0.05).After treatment,the traditional Chinese medicine syndrome score of the observation group was lower than that of the control group,the levels of serum gastrin and motilin were higher than those of the control group,and the levels of inflammatory factors(C-reactive protein,interleukin-6,tumor necrosis factor-α)were lower than those of the control group,and the differences were statistically significant (P＜0.05).Conclusion On the basis of symptomatic treatment,the introduction of Zuozhi Liujun Decoction into the treatment of patients with liver-stomach disharmony type Hp positive chronic gastritis can improve the clinical comprehensive treatment effect,and the effect is significant,so it is recommended for reference. 2024 Vol. 31 (15): 77-80转85 [Abstract] ( 16 ) HTML (1 KB)  PDF (525 KB)  ( 2 ) 81 Clinical effect of acupuncture on Jueyin meridian combined with Xiaoyao Pills in the treatment of breast hyperplasia of liver depression and qi stagnation JIE Liyun1 LIN Qiufang1▲ WEI Yinmei2 ZHANG Sheng1 ZHANG Lingling1 Objective To investigate the clinical effect of acupuncture on Jueyin meridian combined with Xiaoyao Pills in the treatment of breast hyperplasia of liver depression and qi stagnation.Methods From July 2022 to June 2023,a total of 70 patients with breast hyperplasia of liver depression and qi stagnation in Nanping People's Hospital were selected as the research objects.According to the random number table method,they were divided into the control group (35 cases)and the experimental group(35 cases).The control group was treated with Xiaoyao Pills,and the experimental group was treated with acupuncture on Jueyin meridian+Xiaoyao Pills.The total effective rate,traditional Chinese medicine syndrome score,maximum diameter of mass,thickness of hyperplastic gland,visual analogue scale(VAS),breast mass,generic quality of life inventory-74(GQOLI-74)were compared between the two groups.Results The total effective rate of the experimental group(91.43%) was higher than that of the control group (71.43%),and the difference was statistically significant (P＜0.05).Before treatment,there were no statistically significant differences in traditional Chinese medicine syndrome score,maximum diameter of tumor,thickness of hyperplastic gland,VAS,breast mass score,and GQOLI-74 score between the two groups (P＞0.05).After treatment,all of the traditional Chinese medicine syndrome scores of the experimental group were lower than those of the control group,the maximum diameter of the tumor and the thickness of the hyperplasia gland of the experimental group were lower than those of the control group,the VAS and breast mass scores of the experimental group were lower than those of the control group,and the GQOLI-74 scores of the experimental group were higher than those of the control group,and the differences were statistically significant (P＜0.05).Conclusion The effect of acupuncture on Jueyin meridian+Xiaoyao Pills is more ideal,which can promote the rapid disappearance of symptoms,reduce pain,promote the reduction of mass,and improve the quality of life of patients. 2024 Vol. 31 (15): 81-85 [Abstract] ( 19 ) HTML (1 KB)  PDF (515 KB)  ( 34 ) 86 Effect of modified Xiangbei Yangrong Decoction and Xiaoyao Powder on adjunctive chemotherapy in patients with breast cancer and its influence on immune function WANG Xin ZHANG Shiwen WANG Yumei ZHU Hui WU Honghao LI Guoqing Objective To study the effect of modified Xiangbei Yangrong Decoction and Xiaoyao Powder on adjunctive chemotherapy in patients with breast cancer and its influence on immune function.Methods Sixty patients with breast cancer admitted to Ganzhou Hospital of Traditional Chinese Medicine from January 2022 to February 2023 were selected as the study objects,and they were divided into control group and observation group according to random number table method,with 30 cases in each group.The control group received AC chemotherapy regimen,while the observation group received AC chemotherapy regimen combined modified Xiangbei Yangrong Decoction and Xiaoyao Powder.The efficacy,traditional Chinese medicine symptom score,immune function and safety of the two groups were compared.Results The total effective rate and safety of the observation group were higher than those of the control group,and the differences were statistically significant (P＜0.05).The traditional Chinese medicine symptom score of the observation group was lower than that of the control group after treatment,and the difference was statistically significant (P＜0.05).After treatment,the levels of CD3+,CD4+,CD4+/CD8+ and natural killer cells in the observation group were higher than those in the control group,and the level of CD8+was lower than that in the control group,with statistical significances(P＜0.05).Conclusion Modified Xiangbei Yangrong Decoction combined with Xiaoyao Powder is effective in adjuvant chemotherapy for breast cancer,and can also improve its immune function,with high safety. 2024 Vol. 31 (15): 86-89 [Abstract] ( 17 ) HTML (1 KB)  PDF (519 KB)  ( 67 ) 90 Application effect of traditional Chinese medicine soaking combined with recombinant epidermal cells in pressure ulcer patients YAN Tingrong CHENG Xiaoping GAO Minglong CHEN Liming LI Xuehong MAO Zhi Objective To explore the application effect of traditional Chinese medicine soaking combined with recombinant epidermal cells in patients with pressure ulcers.Methods Sixty patients with pressure ulcers admitted to Guixi Traditional Chinese Medicine Hospital from January 2022 to June 2023 were selected as the study subjects.They were divided into control group and observation group using the random number table method,with 30 cases in each group.The control group was treated with recombinant epidermal growth factor method,while the observation group was treated with traditional Chinese medicine soaking on the basis of the control group.The effective rate of wound healing,inflammatory factor levels,symptom relief time,and transforming growth factor-β1(TGF-β1)of the two groups after intervention were analyzed.The expression level of vascular endothelial growth factor(VEGF)and the incidence of adverse reactions.Results The comparison of TGF-β1,VEGF expression level and inflammatory factor level of the two group before treatment showed no statistically significant differences(P＞0.05).After treatment,the expression levels of TGF-β1,VEGF and inflammatory factors of the observation group were lower than those of the control group,and the differences were statistically significant (P＜0.05).The symptom relief time and incidence of adverse reactions in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The total effective rate of wound healing in the observation group was higher than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion In clinical practice,the use of recombinant epidermal growth factor combined with traditional Chinese medicine soaking is more effective in repairing pressure ulcer wounds.The total effective rate of wound healing in patients is improved,the time for symptom relief is shortened,the incidence of adverse reactions is low,the safety is high,and the effect is significant.The clinical application value is high. 2024 Vol. 31 (15): 90-93转98 [Abstract] ( 18 ) HTML (1 KB)  PDF (530 KB)  ( 0 ) 94 Clinical effect of Fondaparinux Sodium combined with Modified Shoutai Formula in the treatment of recurrent spontaneous abortion with positive anti cardiolipin antibody due to kidney deficiency and blood stasis FANG Fang CHEN Xiaoyong Objective To explore the effect of Fondaparinux Sodium combined with Modified Shoutai Formula in the treatment of recurrent spontaneous abortion(RSA)with positive anti cardiolipin antibody due to kidney deficiency and blood stasis.Methods A total of 105 RSA patients admitted to Jiangxi Maternal and Child Health Hospital from January to December 2021 were selected as research objects,and they were divided into simple Chinese medicine group,control group and observation group according to random number table method,with 35 cases in each group.The simple Chinese medicine group was treated with Modified Shoutai Formula,the control group was treated with Enoxaparin+Modified Shoutai Formula,and the observation group was treated with Fondaparinux Sodium+Modified Shoutai Formula.The efficacy,negative conversion rate of anti cardiolipin antibody,coagulation index and adverse reactions of the three groups were observed.Results The total effective rate of patients in the observation group and control group at 12 weeks of pregnancy was higher than that in the simple traditional Chinese medicine group,with statistical significant difference(P＜0.017).However,there was no statistical significant difference in the total effective rate between the observation group and the control group(P＞0.017).The conversion rate of anticardiolipin antibodies in the observation group and the control group was higher than that in the simple traditional Chinese medicine group,with statistical significant difference (P＜0.017).The conversion rate of anticardiolipin antibodies in the observation group was higher than that in the control group,with a statistical significant difference(P＜0.017).The difference in the conversion rate of anticardiolipin antibodies among the three groups was statistically significant (P＜0.05).At 12 weeks of pregnancy,the serum D-dimer levels,coagulation index,and maximum amplitude of the three groups of patients were lower than those before treatment,and the indexes of observation group and control group were lower than those of the simple traditional Chinese medicine group,with statistical significant differences(P＜0.05).However,there were no statistical significant differences in coagulation related indicators between the observation group and the control group(P＞0.05).During the treatment period,there were no adverse reactions in the group treated with traditional Chinese medicine alone.The incidence of skin reactions and elevated transaminases at the injection site in the control group were higher than those in the observation group,with a statistical significant difference(P＜0.05).Conclusion The effect of Fondaparinux Sodium combined with Modified Shoutai Formula in the treatment of RSA patients with positive anti cardiolipin antibody of kidney deficiency and blood stasis is significant,which can effectively improve the clinical symptoms and coagulation status,promote the negative conversion of anti cardiolipin antibody,and has better safety. 2024 Vol. 31 (15): 94-98 [Abstract] ( 16 ) HTML (1 KB)  PDF (531 KB)  ( 0 ) 99 Analysis of spiritual needs of patients with gynecological malignant tumor and influencing factors MEI Cailing ZHU Ping▲ Objective To investigate the spiritual needs of patients with gynecological malignant tumors and analyze the influencing factors.Methods A total of 145 gynecological malignant tumor patients admitted to Ganzhou People's Hospital from October 2021 to October 2023 were selected as the study objects,the Chinese version of perceptive social support scale(PSSS),Chinese version of spiritual need scale (SNS) and general data questionnaire were used for investigation.Patients were divided into demand group(n=107)and control group(n=38)according to whether they had spiritual needs.The influencing factors of spiritual needs of patients with gynecological malignant tumors were analyzed by univariate analysis and logistic regression.Results The spiritual need score of 145 patients with gynecological malignant tumor was (76.94±10.85),among which 107 patients had spiritual need,accounting for 73.79%.There were no significant differences in age,marital status,number of children,place of residence,disease type,tumor stage and permanent caregiver between the demand group and control group(P＞0.05).There were significant differences in cultural level,religious belief,course of disease,per capita family income and social support between the two groups(P＜0.05).Logistic regression analysis results indicated that the education level of college or above (β=1.138,OR=3.119,95%CI=1.098-8.864),religious belief (β=2.231,OR=10.108,95%CI=1.236-82.627),disease duration＞12 months(β=1.385,OR=3.994,95%CI=1.491-10.698),family per capita income≥4 000 yuan (β=1.668,OR=5.408,95%CI=1.443-20.265) and high social support (β=1.002,OR=2.724,95%CI=1.109-6.691)were risk factors for spiritual needs in patients with gynecological malignant tumors (P＜0.05).Conclusion The spiritual needs of patients with gynecological malignant tumors are at a medium to high level,which is influenced by the patients'cultural level,religious belief,disease course,family per capita income and social support. 2024 Vol. 31 (15): 99-102转107 [Abstract] ( 15 ) HTML (1 KB)  PDF (537 KB)  ( 11 ) 103 Analyzed the influencing factors of breast-feeding in primiparas during hospitalization based on information-motivation-behavioral skills model CHEN Jinxiu LI Qinghua FAN Yun CAI Huimian ZHANG Suchun CHEN Xinhui Objective To investigate the current situation of primiparas' breast-feeding during hospitalization and analyze the influencing factors of breast-feeding during hospitalization,in order to provide basis for clinical health education.Methods Using the convenient sampling method,271 primiparas who gave birth in the Department of Obstetrics of Guangzhou Women and Children's Medical Center from January to June 2022 were selected as the research objects.A questionnaire survey based on the information-motivation-behavioral skills model (IMB) was conducted.Multivariate logistic regression was used to analyze the influencing factors of breast-feeding during hospitalization.Results The rate of breast-feeding during hospitalization was 67.9% (184/271).Breast-feeding education during hospitalization (OR=9.223,P=0.002,95%CI=2.243-37.935),postpartum breast-feeding knowledge (OR=0.885,P=0.029,95%CI=0.793-0.988),breast-feeding attitude(OR=0.900,P＜0.001,95%CI=0.861-0.940),breast-feeding self-efficacy(OR=0.963,P=0.011,95%CI=0.935-0.991)and feeding quality (OR=0.746,P＜0.001,95%CI=0.634-0.877) were the influencing factors for non breast-feeding in primiparas.Conclusion Based on the IMB,the influencing factors of breast-feeding during the hospitalization of primipara are analyzing from the dimensions of information,motivation,behavioral skills and behavior.It was found that breast-feeding during the hospitalization of primipara is affecting by many factors,and breast-feeding education should be strengthened,maternal knowledge of breast-feeding should be improved,maternal attitude to breast-feeding should be improved,maternal self-efficacy should be enhanced,and maternal breast-feeding skills should be mastered.Improve the quality of breast-feeding,thereby increasing breast-feeding rates and promoting maternal and child health. 2024 Vol. 31 (15): 103-107 [Abstract] ( 16 ) HTML (1 KB)  PDF (536 KB)  ( 0 ) 108 Qualitative research on the self-protection of occupational exposure of undergraduate nursing interns in clinical practice based on protection motivation theory SUN Zhaoqing1 LI Qianqian2 Objective To conduct a qualitative research on the cognition of undergraduate nursing interns on occupational exposure self-protection after entering clinical practice based on protection motivation theory (PMT),analyze the problems and deficiencies existing in schools and hospitals in occupational exposure self-protection education,and provide reference for schools and hospitals to further improve the occupational protection ability of nursing interns in the future.Methods A total of 13 undergraduate nursing interns who had been practicing for more than 3 months in a Third Grade First Class Hospital in Shanxi Province from September to December 2023 were selected as the respondents for semi-structured interviews.The interview outline was made based on PMT,the phenomenological research method in qualitative research was adopted,and the theme was extracted.Results After interview,four themes were summarized,namely,nursing interns'poor cognitive level of occupational exposure and self-protection awareness,lack of humanistic care,lack of practical education of nursing interns'occupational protection skills,and lack of systematic occupational safety related courses in school and hospital education.Conclusion Schools and hospitals should formulate relevant occupational protection education and teaching plans from the perspective of motivation and guided by the seven core themes of PMT,improve the protection cognition level of nursing interns,reduce the occupational exposure phenomenon in the process of clinical practice,and lay a good foundation for further entering the clinical work. 2024 Vol. 31 (15): 108-111 [Abstract] ( 15 ) HTML (1 KB)  PDF (526 KB)  ( 2 ) 112 Analysis and reflection on the results of key monitoring drug reviews in Suqian First Hospital LIU Hua JIA Zengyong TONG Deyin LIU Zhiguo▲ Objective Strengthen the management of key monitoring drugs and promote rational clinical drug use.Methods A list of key monitoring drugs was established.Clinical pharmacists of Suqian First Hospital made reasonable comments on the top 10-20 key monitoring drugs.Multiple departments jointly carried out the rational drug use group review meeting,released the review results through the hospital Intranet,deducted the relevant doctors or departments,and if necessary,the Commission for Discipline Inspection took the lead to interview the relevant personnel.Results Compared with 2019,the proportion of drugs in 2020 decreased from 35.87% to 34.29%,the proportion of key monitoring drugs decreased from 10.81%to 4.47%,and the cost of key monitoring drugs per discharged patient decreased from 676.66 yuan to 297.63 yuan.The per capita cost of discharged patients decreased from 12 783.57 yuan to 11 789.09 yuan,the proportion of essential drugs increased from 29.44% to 32.41%,and the antibiotics use density decreased from 47.39 to 44.17.Conclusion The review of key monitoring drugs can reduce the proportion of drugs,reduce the use of key monitoring drugs,reduce the hospitalization costs of patients,and promote rational clinical drug use. 2024 Vol. 31 (15): 112-115 [Abstract] ( 16 ) HTML (1 KB)  PDF (446 KB)  ( 20 ) 116 Application effect analysis of total quality management in the quality improvement of the first page of inpatient medical records in the background of diagnosis-intervention packet ZOU Pang1 FU Jiajing2 LIU Fangping1 TU Mei3▲ Objective To explore the application effect of total quality management in the quality improvement of the first page of inpatient medical records under the background of diagnosis-intervention packet (DIP).Methods A total of 1 346 inpatient medical records before and after total quality management in Longyan First Hospital from 2021 to 2022 were selected as the research objects.In the context of DIP,the incidence of defects in patient cost information,diagnosis and treatment information,hospitalization process information and basic information on the first page of inpatient medical records before and after the implementation of total quality management was compared,as well as the pass rate of major diagnosis,other diagnosis,major surgical operation,and other surgical operation filling and coding.Results In the context of DIP,the incidences of defects in cost information,diagnosis and treatment information,hospitalization process information and basic information on the first page of medical records was lower than those before total quality management,and the pass rates of main diagnosis,other diagnosis,major surgical operation,and other surgical operation filling and coding on the first page of medical records were higher than those before total quality management,the differences were statistically significant (P＜0.05).Conclusion The application of total quality management in the quality improvement of the first page of inpatient medical records under the background of DIP can effectively reduce the incidence of information defects on the first page of patient medical records and improve the pass rates of disease diagnosis,surgical procedure filling and coding on the first page of medical records,which is worthy of clinical promotion and application. 2024 Vol. 31 (15): 116-119 [Abstract] ( 15 ) HTML (1 KB)  PDF (447 KB)  ( 50 ) 120 Discussion on the scenario simulation teaching model of naval war trauma treatment DONG Zhitao GENG Li ZHU Hengmei WEI Kai QIAO Suchi XUE Qiang FU Xiaohui LIU Hui▲ The treatment of naval trauma is an important part of naval medical and health work,as well as a difficult and key point in naval medical education.This article introduces the application experience of scenario simulation teaching method in naval trauma treatment courses,explores the theoretical basis,implementation process,and exploration experience of new models of scenario simulation teaching method,and provides an effective teaching mode and research direction for naval medical and health education.The scenario simulation teaching method is a teaching method that constructs realistic,situational,and challenging teaching scenarios based on the characteristics and challenges of naval combat injuries,guiding students to play different roles,engage in communication,discussion,decision-making,and other activities in a simulated real environment,in order to achieve learning objectives.The scenario simulation teaching method can enhance students' cognition and understanding of naval trauma treatment,cultivate their clinical thinking and operational abilities,and enhance their adaptability and teamwork abilities.The new models of situational simulation teaching methods,such as the problem-based learning teaching method of small class rotation and the situational teaching method of flipped classroom,can be combined with other effective teaching methods to provide more diverse,flexible,and innovative choices for situational simulation teaching. 2024 Vol. 31 (15): 120-123转128 [Abstract] ( 16 ) HTML (1 KB)  PDF (553 KB)  ( 355 ) 124 Exploration of teaching strategies for basic nursing courses from the perspective of the National Vocational College Teaching Ability Competition GUO He GUO Juan CUI Zizhi LI Luliang TIAN Qian The Ministry of Education of the People's Republic of China has promoted the deepening of teaching reform in vocational education through the vocational college skills competitions and teaching ability competition.Driven by digitization,informatization and intelligence,it has continuously improved and developed the construction of new vocational education facilities.Digital technology has provided a new educational path for vocational education,and vocational education has ushered in a new era of transformation.Then vocational college teachers face new challenges and opportunities in education and teaching.Improving the digital application ability of teachers and students,and putting education as the foundation into practice,is the current and future focus of vocational education.The basic nursing course is one of the important courses in the second group of vocational colleges that have participated in teaching ability competitions over the years.This course is one of the core courses for nursing majors in vocational colleges.The competition encourages participating teachers to have a deeper understanding of the teaching of this course and explore how to transform the results of the competition into guiding teaching.This article takes participating in the National Vocational College Skills Competition Teaching Ability Competition as the starting point,exploring the implementation of digital teaching reform in basic nursing courses,and form a teaching implementation report using nursing first-aid techniques projects as an example,the implementation of digital technology teaching reform in this course has certain practical guiding significance. 2024 Vol. 31 (15): 124-128 [Abstract] ( 19 ) HTML (1 KB)  PDF (548 KB)  ( 132 ) 129 Research on the mixed teaching mode of massive open online courses and small private online courses in pathology teaching YUAN Rong The mixed teaching mode of massive open online courses(MOOC)and small private online courses (SPOC) are the new type of teaching modes.This article presents the specific teaching steps of MOOC and SPOC teaching modes in the implementation of pathology teaching,highlighting the advantages of blended teaching mode.This new teaching mode not only greatly mobilizes students'learning enthusiasm and initiative,but also increases communication between teachers and students in the classroom and team spirit,thereby enhancing students' clinical thinking ability,it has brought a positive impact on cultivating students' subjectivity in learning.At present,more and more teachers in China are adopting this teaching method for teaching.Both students and teachers believe that this new teaching mode greatly improves learning efficiency and is worth promoting widely.Effectively combining MOOC and SPOC teaching modes to cultivate high-quality and professional health professionals,this article conducts certain research in order to promote the high-quality development of pathology teaching in higher vocational education. 2024 Vol. 31 (15): 129-132转148 [Abstract] ( 17 ) HTML (1 KB)  PDF (1010 KB)  ( 48 ) 133 A case report of renal atrophy caused by uterine endometriosis of the ureter CAO Yingying1 XU Hongbin2▲ Ureteral endometriosis (UE) refers to the ectopic implantation of uterine endometrial tissue that invades the ureter and the surrounding tissues,leading to pathological changes.It is a rare subtype of endometriosis,and its exact etiology remains unclear.However,recurrent cyclic bleeding from ectopic endometrium can trigger inflammatory reactions,tissue fibrosis,adhesions,and subsequent infiltration into the ureteral mucosa,muscular layer,or outer serosa.This condition has a low incidence and is often underrecognized in clinical practice,leading to misdiagnosis or delayed diagnosis.On February 6th,2023,a 47-year-old female patient with a history of recurrent right-sided lower back pain for over 4 years and a prior diagnosis of endometriosis,was admitted to Shenzhen People's Hospital.She had undergone two surgeries for“endometriosis”,one cesarean surgery,and two uterine fibroid removal procedures.She had also been previously diagnosed with right ureteral stenosis and had undergone a right ureteroscopy,ureteral dilation,and placement of a ureteral stent.However,her pain persisted even after the removal of the ureteral stent.During this hospitalization,comprehensive imaging studies,including ultrasound and MRI were performed,leading to a possible diagnosis of ureteral endometriosis.Surgical treatment was carried out successfully,and postoperative pathology confirmed right ureteral endometriosis.The patient received gonadotropin-releasing hormone agonist (GnRH-a)therapy for six cycles and has shown good efficacy during the six-month follow-up. 2024 Vol. 31 (15): 133-137 [Abstract] ( 17 ) HTML (1 KB)  PDF (495 KB)  ( 102 ) 138 Pharmaceutical care of a patient with intracranial infection of carbapenem-resistant enterobacter aerogenes LIN Huiguo1 TAN Hongping2 SU Fanghua1▲ Intracranial infection is a common serious complication after neurosurgery.Clinical pharmacists participated in the whole process of anti-infective treatment of a patient with intracranial infection of carbapenem-resistant enterobacter aerogenes after neurosurgery,analyzed the rationality of anti-infective treatment drugs,put forward medication suggestions,and conducted targeted pharmaceutical care.Clinical pharmacists closely combine the characteristics and changes of the patient's condition,and assist clinicians in formulating an individualized anti-infection treatment plan according to the pharmacokinetic/pharmacodynamic theory of antibacterial drugs.By extending the infusion time of Meropenem combined with intravenous Amikacin and intrathecal injection,sequential Levofloxacin treatment plan,surgical debridement and drainage,etc.The successful treatment of intracranial infection of carbapenem-resistant enterobacter aerogenes reflects the value of clinical pharmacists in the clinical treatment of intracranial infection. 2024 Vol. 31 (15): 138-143 [Abstract] ( 16 ) HTML (1 KB)  PDF (703 KB)  ( 91 ) 144 Application effect of nurse classification authorization management model in patients with severe pneumonia in intensive care unit LI Bin TANG Libin▲ Objective To observe the effect of nurse classification authorization management model in patients with severe pneumonia in intensive care unit (ICU).Methods A total of 490 patients with severe pneumonia admitted to the ICU of the 909th Hospital of Joint Logistic Support Force(Southeast Hospital Affiliated to Xiamen University)from January 2021 to December 2022 were selected as the study objects,and they were divided into the control group (240 cases) and the experimental group (250 cases)according to the order of admission time.The control group was given routine nursing mode,and the experimental group was given nurse classification authorization management model.Blood lactic acid,acute physiological and chronic health evaluation (APACHEⅡ) score,white blood cell count recovery time,mechanical ventilation time,fever reduction time and complication rate were compared between the two groups before and after intervention.Results After intervention,the lactic acid level and APACHEⅡscore of experimental group were lower than those of control group,and the lactic acid clearance was higher than that of control group,the white blood cell count recovery time,mechanical ventilation time and fever reduction time of experimental group were shorter than those of control group,the complication rate of experimental group was lower than that of control group,and the differences were statistically significant (P＜0.05).Conclusion Nurse classification authorization management model can effectively improve the physiological indexes of ICU patients with severe pneumonia and reduce the occurrence of complications. 2024 Vol. 31 (15): 144-148 [Abstract] ( 16 ) HTML (1 KB)  PDF (737 KB)  ( 1 ) 149 Application effect of standardized nursing procedure of modified negative pressure drainage in children with giant scalp hematoma CHENG Wen CHEN Pei ZOU Jing Objective To explore the effect of standardized nursing procedure of modified negative pressure drainage in children with giant scalp hematoma.Methods Fifty pediatric patients with giant scalp hematoma admitted to the Department of Pediatric Surgery of Jiujiang Maternal and Child Health Hospital from January 2018 to August 2023 were selected as the study objects.They were divided into control group and study group according to the order of admission time,with 25 cases in each group.The control group adopted the routine nursing of modified negative pressure drainage,and the study group adopted the standardized nursing of modified negative pressure drainage.The incidence of complication,rehabilitation index,nursing quality score and total nursing satisfaction were compared between the two groups.Results The total complication rate and unplanned operation rate of the study group were lower than those of the control group,the time required for drainage,wound healing and hospitalization were shorter than those of control group,the score of disease mastery,risk assessment,drainage maintenance,nurse-patient communication,total nursing quality score and total nursing satisfaction rate were higher than those of control group,with statistical significances (P＜0.05).Conclusion The standardized nursing procedure of modified negative pressure drainage has definite effect on the giant scalp hematoma in children,and can effectively reduce the occurrence of complications and shorten the hospital stay of children through high quality nursing. 2024 Vol. 31 (15): 149-152 [Abstract] ( 17 ) HTML (1 KB)  PDF (729 KB)  ( 68 ) 153 Application effect of emotional ABC theory in rehabilitation nursing education for patients with shoulder periarthritis WU Meina YU Yanqiu WU Juxia▲ Objective To explore the application effect of emotional ABC theory in rehabilitation nursing education for patients with shoulder periarthritis.Methods A total of sixty patients with shoulder periarthritis admitted to the Fourth Affiliated Hospital of Nanchang University from March to October 2022 were selected as the study subjects.They were divided into control group (30 cases) and observation group (30 cases) using random number table method.The control group received routine care,while the observation group received emotional ABC theory intervention on the basis of routine care.Both groups continued to receive intervention and observation for 2 months.Disease knowledge,mental state,shoulder function recovery and quality of life were compared between the two groups.Results After intervention,the disease knowledge,the University of California at Los Angeles shoulder rating scale (UCLA) score and short form 36 health survey (SF-36) scores of the observation group were higher than those of the control group,with statistical significances(P＜0.05).After intervention,the scores of self-rating depression scale (SDS) and self-rating anxiety scale (SAS) in observation group were lower than those in control group,with statistical significances (P＜0.05).Conclusion Adopting emotional ABC theory intervention in rehabilitation nursing education for patients with shoulder periarthritis can improve their mastery of disease knowledge,alleviate their negative emotions,promote shoulder joint function recovery,and further improve their quality of life. 2024 Vol. 31 (15): 153-156转161 [Abstract] ( 15 ) HTML (1 KB)  PDF (716 KB)  ( 35 ) 157 Effect of chloral hydrate retention enema based on PDCA circulation on sedation and sleep of infants in emergency department LIU Lina LIU Qingqing DUAN Meihua DING Ming'e HAN Jiayu LI Miaomiao Objective To analyze the sedative sleep effect of chloral hydrate retention enema using PDCA cycle method on infants and young children in emergency department.Methods A total of 80 infants and young children who received chloral hydrate retention enema treatment in Ganzhou Women and Children's Health Care Hospital from July 2021 to August 2022 were selected as the study objects.The patients were divided into observation group (40 cases)and control group(40 cases)in the order of admission.The control group received routine care,while the observation group received PDCA cycle care.The sedative effect,sleep onset time,sleep maintenance time,and enema overflow between two groups of pediatric patients were compared.Results The proportion of total effective rate in the observation group was higher than that in the control group,and the difference was statistically significant (P＜0.05).The onset time of sleep of the observation group was shorter than that of the control group,with a statistically significant difference (P＜0.05).The sleep maintenance time of the observation group was longer than that of the control group,with statistically significant difference(P＜0.05).The proportion of enema overflow in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The retention enema of chloral hydrate based on the PDCA cycle method is beneficial for enhancing sedative effects,improving both sleep onset and maintenance time,and is worthy of clinical application. 2024 Vol. 31 (15): 157-161 [Abstract] ( 16 ) HTML (1 KB)  PDF (714 KB)  ( 15 ) 162 Application value of personalized intervention under risk warning analysis in the nursing of intensive care unit patients with ventilator-associated pneumonia LIANG Ling1 HU Zhuqin1 CHEN Danli2 Objective To explore the application value of personalized intervention under risk warning analysis in the nursing of patients with ventilator-associated pneumonia in the intensive care unit (ICU).Methods A total of 82 patients with ventilator-associated pneumonia admitted to the ICU of Yichun People's Hospital from February 2022 to June 2023 were selected as the study objects and divided into observation group(41 cases)and control group(41 cases)according to the random number table method.The control group received routine care,while the observation group received personalized nursing intervention under risk warning analysis.Both groups continued to receive care until the patients were discharged.The comfort level,incidence of complications,prognosis recovery,and quality of life between two groups were compared.Results The general comfort questionnaire(GCQ)score and the MOS item short from health survey(SF-36)score of the observation group after nursing were higher than those of the control group,and the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The mechanical ventilation time,ICU stay time,and hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant (P＜0.05).Conclusion Individualized intervention under risk warning analysis can improve the comfort of ICU patients with ventilator pneumonia,effectively reduce the incidence of complications,promote patient recovery as soon as possible,and thus improve their quality of life. 2024 Vol. 31 (15): 162-165转171 [Abstract] ( 18 ) HTML (1 KB)  PDF (739 KB)  ( 76 ) 166 Application of self-management plan in hypertensive chronic nephropathy patients with deficiency both of qi and yin combined with dampness syndrome WANG Yuting ZHU Xiaohong WANG Shuifa LIU Meiling WANG Lingli Objective To explore the application value of self-management plan in hypertensive chronic nephropathy patients with deficiency both of qi and yin combined with dampness syndrome.Methods A total of 128 patients with hypertensive chronic nephropathy with deficiency both of qi and yin combined with dampness syndrome diagnosed and treated by the Third People's Hospital of Jingdezhen from February to August 2023 were selected as research objects.According to random number table method,they were divided into observation group (self-management program)and control group(routine care),64 cases each.Systolic blood pressure,diastolic blood pressure,serum creatinine(Scr),urinary albumin excretion rate(UAER)and microalbumin(mALB),self-management behavior and quality of life were compared between the two groups at 24 h.Results After intervention,24 h systolic blood pressure,diastolic blood pressure,Scr,UAER and mALB in observation group were lower than those in control group,with statistical significances (P＜0.05).The proportion of reasonable exercise,salt intake control,psychological adjustment,blood pressure monitoring,regular medication and regular review in observation group was higher than that in control group,with statistical significances (P＜0.05).The scores of physiological function(PF),role physical(RP),boby pain(BP),general health(GH),vitality(VT),social function(SF),role emotional(RE)and mental health (MH)in the observation group were higher than those in the control group,with statistical significances(P＜0.05).Conclusion The application of self-management plan in patients with hypertensive chronic nephropathy with deficiency both of qi and yin combined with dampness syndrome is beneficial to reduce blood pressure,improve kidney function and quality of life. 2024 Vol. 31 (15): 166-171 [Abstract] ( 17 ) HTML (1 KB)  PDF (891 KB)  ( 12 ) 172 Effect analysis of networked cognitive behavioral therapy on sleep quality and fatigue in patients with nasopharyngeal carcinoma LIN Ping1 XIAO Weiyun2▲ YUAN Yeqin1 Objective To explore the effects of networked cognitive behavioral therapy on sleep quality and fatigue in patients with nasopharyngeal carcinoma.Methods A total of 250 patients with nasopharyngeal carcinoma admitted to Jiangxi Cancer Hospital from June 2022 to February 2023 were selected as research objects,they were divided into observation group and control group according to random number table method,with 125 patients in each group.The control group received routine nursing,and the observation group received networked cognitive behavioral therapy on the basis of the control group.Both groups received continuous nursing observation for 4 weeks.The psychological state,sleep quality,fatigue and quality of life of the two groups were compared.Results The various scores of sympotom checklist 90(SCL-90)in the observation group were lower than those in the control group,the differences were statistically significant(P＜0.05).The scores of Pittsburgh sleep quality index(PSQI)and cancer fatigue scale(CFS)after nursing in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).The various scores of quality of life brief scale (QOL-BREF)in the observation group were higher than those in the control group,with statistical significances (P＜0.05).Conclusion Networked cognitive behavioral therapy can reduce the negative emotions and fatigue of nasopharyngeal cancer patients,improve their sleep quality,and thus improve the quality of life of patients. 2024 Vol. 31 (15): 172-175 [Abstract] ( 17 ) HTML (1 KB)  PDF (699 KB)  ( 1 ) 176 Application of Teach-back health education in in vitro fertilization-embryo transfer assisted pregnant elderly patients HONG Min LONG Aihua LIU Yanhua Objective To study and analyze the effect of Teach-back health education on intervention in in vitro fertilization-embryo transfer assisted pregnant elderly patients.Methods A total of 80 cases of in vitro fertilization-embryo transfer assisted pregnant elderly patients admitted to Ganzhou Women and Children's Health Care Hospital from June 2022 to August 2023 were selected as the study objects,and they were divided into observation group (40 cases)and control group(40 cases) by odd-even number method.The self-rating anxiety scale (SAS),satisfaction with health education,treatment compliance and pregnancy success rate were compared between the two groups before and after the intervention.Results There was no significant difference in SAS score between the two groups before intervention (P＞0.05).The SAS scores of the two groups after intervention was lower than those before intervention,and the score of observation group was lower than that of the control group,the differences were statistically significant (P＜0.05).The total satisfaction of health education in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).The total treatment compliance of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).The pregnancy success rate in the observation group was higher than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The implementation of Teach-back health education in the clinical intervention of in vitro fertilization-embryo transfer to assist elderly pregnant patients can effectively improve the psychological state of patients,improve patients' satisfaction with health education and compliance with treatment,and thus improve the success rate of pregnancy,which is worthy of clinical promotion and application. 2024 Vol. 31 (15): 176-179 [Abstract] ( 18 ) HTML (1 KB)  PDF (710 KB)  ( 0 ) 180 Effect of sitting Baduanjin on rapid rehabilitation of patients with Standford B aortic dissection ZHANG Jia ZHOU Yashan ZHENG Chunyan LIU Yanjun LIU Jie Objective To explore the effect of sitting Baduanjin on the rapid rehabilitation of patients with Standford B Aortic dissection (TBAD).Methods A total of 50 patients with TBAD admitted to Second Affiliated Hospital of Nanchang University from January 2021 to December 2022 were selected as the study objects.They were divided into observation group (25 cases) and control group (25 cases) according to random number table method.The control group adopted the routine rehabilitation exercise program,and the observation group adopted the routine rehabilitation exercise program combined with sitting Baduanjin.The pain degree,activity of daily living (ADL) scale,exercise endurance and nursing satisfaction were compared between the two groups.Results Pain scores of both groups were lower than those before intervention,and the score of observation group was lower than that of control group,the differences were statistically significant(P＜0.05).One month after discharge,the ADL scores of the two groups were higher than those before intervention,and the 6-min walking distance(6MWT)were longer than those before intervention,and the ADL score of the observation group was higher than that of the control group,and the 6MWT was longer than that of the control group,with statistical significances(P＜0.05).The total satisfaction of nursing in the observation group was higher than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Sitting Baduanjin can effectively relieve pain,improve the ability of activities of daily living,exercise endurance and nursing satisfaction in patients with TBAD after operation. 2024 Vol. 31 (15): 180-183 [Abstract] ( 18 ) HTML (1 KB)  PDF (710 KB)  ( 0 ) 184 Research progress on the effect of inhalation aromatherapy on anxiety in patients with surgery and physical diseases CHEN Yufen1 CHEN Zhizhong2 With the development of society,anxiety has gradually become a common mental state of people,especially the anxiety caused by disease.Although there are many kinds of drugs used to treat anxiety and therapeutic efficacy is good,there are many side effects,which may cause drug dependence and abuse.Inhalation aromatherapy refers to the olfactory receptor recognition of odor molecules through the olfactory pathway to the olfactory cortex,and then to affect the mood.Inhaled aromatherapy is a very simple and relatively inexpensive method that is not limited by time,place,or external conditions.In order to understand the current status of the research on the effects of inhalation aromatherapy on disease-related anxiety,the relevant literatures were consulted,and the possible future research directions were further discussed on the basis of the current research,it provides a new possible angle of view for future research.It can also reduce the use of anti-anxiety drugs,reduce the side effects caused by the drugs,and reduce the dependence and abuse of anti-anxiety drugs. 2024 Vol. 31 (15): 184-188 [Abstract] ( 18 ) HTML (1 KB)  PDF (538 KB)  ( 158 ) 189 Research progress of adipose-derived stem cells in the treatment of rheumatoid arthritis YU Yifan LIU Kejie Maimaititu'ersun Kaisai'erjiang▲ Rheumatoid arthritis is a chronic autoimmune disease that progresses to cause severe damage to the joints and surrounding tissues.At present,the main methods at home and abroad are to slow down the course of the disease by means of drug therapy after timely diagnosis,and help patients improve and maintain joint mobility and muscle strength.Although the current treatment methods of rheumatoid arthritis are relatively mature,more safe and effective therapies are still needed to achieve clinical remission and repair and regeneration of the disease.Studies at home and abroad have found that adipose-derived stem cells have good therapeutic effect in inflammatory arthritis,which has become a research hotspot in recent years.Adipose-derived stem cells are pluripotent stromal cells with low immunogenicity and strong ability of proliferation,differentiation and immune regulation,and can secrete a variety of cytokines to inhibit the occurrence and development of inflammation,providing a new idea for the treatment of rheumatoid arthritis.Based on a large number of Chinese and foreign literatures,this study summarized the progress of adipose-derived stem cells in the treatment of rheumatoid arthritis,in order to provide reference for its clinical research. 2024 Vol. 31 (15): 189-193转198 [Abstract] ( 17 ) HTML (1 KB)  PDF (549 KB)  ( 40 ) 194 Research status of microbial contamination of medical ultrasonic probes and couplings WANG Jinxiao1 WANG Fang2 ZHAO Qianqian2 ZHAO Qingqing1▲ With the development of ultrasonic medical technology,ultrasonic examination technology is more and more applied in clinic,and plays a particularly important role in the screening,diagnosis and treatment of multi-system diseases.Ultrasound technology has developed rapidly in emergency ultrasound and severe ultrasound,and it is also used in the diagnosis and treatment of lung diseases,maternal and child pediatric diseases,intracranial pressure detection,cardiac output detection,and can also change the surgical form and make the surgical method more convenient.It is also used in combination with digital subtraction angiography in the treatment of acute cerebral hemorrhage,guided peripheral venipentesis catheterization,and vaginal ablation in oncology,etc.It is widely used in many systemic diseases.To a great extent,it reduces the pain of patients,shortens the average hospital stay of patients,and reduces the economic and psychological pressure of patients.At the same time,the development of ultrasound technology also makes the medical development face certain problems.Nosocomial infections caused by medical ultrasonography often occur.The use of ultrasonic probe and ultrasonic coupler has become an important factor affecting the incidence of nosocomial infection related to ultrasound examination.Therefore,this paper summarizes how to disinfect medical ultrasonic probes and how to select medical ultrasonic coupler correctly. 2024 Vol. 31 (15): 194-198 [Abstract] ( 17 ) HTML (1 KB)  PDF (532 KB)  ( 55 )

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