Abstract：Objective To study the risk factors of aspirin resistance in patients with coronary heart disease(CHD).Methods The clinical data of patients with CHD admitted into our hospital from January 2012 to April 2017 were retrospectively analyzed.According to inclusion and exclusion criteria,40 patients with aspirin resistance(AR group)or without AR(NAR group)were screened respectively.The general clinical data and the related laboratory indexes were compared between the two groups,and the risk factors of AR in patients with CHD were analyzed.Results The level of retinol-binding protein(RBP)in the AR group was lower than that in the NAR group while the level of creatinine(SCr),Hcy and CD62P were higher than those in the NAR group(P＜0.05).Taken AR as the dependent variable,the Hcy and CD62P were risk factors for AR in patients with CHD,and the risk value of Hcy was highest.Conclusion Hcy and CD62P are the risk factors for AR in patients with CHD,or it can be an effective index in the predicting the AR risk in patients with CHD.
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