Abstract：Objective To explore the clinical effect of Aspirin Enteric-Coated Tablets combined with Clopidogrel in treatment of angina pectoris of coronary heart disease.Methods Altogether 94 cases of patients with angina pectoris of coronary heart disease who were treated in our hospital from January 2016 to October 2017 were selected as the subjects of this research and divided into observation group and control group according to the randomized number method,with 47 cases in each group.Patients in control group were treated only with Aspirin Enteric-Coated Tablets treatment,patients in the observation group were treated with Clopidogrel and Aspirin Enteric-Coated Tablets,the continuous medication was given for 4 weeks.The changes of angina pectoris symptom index,plasma fibrinogen,plasma viscosity and total blood viscosity levels were compared between the two groups before and after treatment.Results After treatment,the interval of angina attack was longer than before treatment,the number of attacks was less than before treatment,the duration was shorter than before treatment,and the differences were statistically significant(P＜0.05).The interval of angina attack of patients in the observation group was longer than that in the control group,the number of attacks of patients in the observation group was less than that in the control group,the duration of patients in the observation group was shorter than that in the control group,and the differences were statistically significant(P＜0.05).After treatment,the plasma fibrinogen,plasma viscosity and total blood viscosity were lower than before treatment,and the differences were statistically significant(P＜0.05).The plasma fibrinogen,plasma viscosity and total blood viscosity of the patients in the observation group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Combination of application of Aspirin Enteric-Coated Tablets and Clopidogrel is effective in the treatment of angina pectoris.It can effectively improve the symptoms of angina pectoris and regulate plasma fibrinogen,plasma viscosity and whole blood viscosity level,which is worthy of clinical promotion and application.
马迪辉. 阿司匹林肠溶片联合氯吡格雷治疗冠心病心绞痛的临床效果[J]. 中国当代医药, 2018, 25(8): 149-151转154.
MA Di-hui. Clinical effect of Aspirin Enteric-Coated Tablets combined with Clopidogrel in treatment of angina pectoris of coronary heart disease. 中国当代医药, 2018, 25(8): 149-151转154.
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