Relationship between heart rate variability and grading of chronic stable angina pectoris and intervention effect by β-blocker
HUANG Zu-jian
The First Department of Internal Medicine,Yangchun Hospital of Traditional Chinese Medicine inYangchun City of Guangdong Province,Yangchun 529600,China
Abstract:ObjectiveTo investigate the relationship between heart rate variability (HRV)and the risk grading of chronic stable angina pectoris(SAP)and the intervention effect by β-blocker.Methods180 patients with chronic stable angina treated in our hospital from May 2015 to May 2017 were selected as the observation group.The observation group was graded according to the severity of angina pectoris of the Canadian cardiovascular society(CCS).At the same time,45 cases of healthy control group in the same period were selected,the time-domain index changes of each group were measured and compared.The observation group was randomly divided into treatment group and control group to analyze the intervention effect of metoprolol on HRV changes in sap patients.ResultsThe severity grade of CCS angina pectoris was significantly lower than that of control group,and HRV decreased linearly with the increase of risk(P<0.01).After metoprolol intervention,the heart rate variability of sap increased significantly (P<0.01).The improvement of SDNN,SDANN,sDN nindex,rMSSD and PNN50 in metoprolol group was better than that in control group (P<0.05).ConclusionThe higher the risk of angina pectoris,the lower the value of HRV.HRV may be a noninvasive method to predict myocardial ischemia and assess the risk.Compared with the control group,the HRV time-domain index of the treatment group improved more significantly than that of the control group.
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