Abstract：Objective To retrospective analyze the characteristics and regularity of adverse drug reactions(ADR)in our hospital,so as to provide reference for clinical rational drug use and risk prevention.Methods A total of 99 cases of ADR reported by our hospital from January 2018 to June 2019 were collected.The sex and age of patients，the route of administration，the types of drugs,ADR involved organs or systems and clinical manifestation,degree grade outcome and relevance evaluation,combined medication,etc.were analyzed retrospectly.Results In 99 ADR reports,women outnumbered men,and the incidence of ADR was higher in children under 12 years old and patients aged 21-50 years old;87 cases(87.88%)were mainly administered intravenously;the main drugs involved in ADR were anti infective drugs and anti-tumor drugs,with the composition ratio of 50.51% and 22.22% respectively;the clinical manifestations of ADR were mainly skin and accessory damage and blood system damage;the general ADR was 64 cases(64.65%),severe ADR was 35 cases(35.35%),mainly anti-tumor drugs.ADR caused by combined drugs was 28 cases(28.28%).Conclusion ADR are related with many kinds of factors． In clinical practice,the administration of drugs for special population should be strengthen,ADR monitoring of intravenous routes of administration should be emphasized,and the use of anti-infection drugs and anti-tumor drugs should be emphasized.Strengthen ADR reporting quality and management system,discover drug use safety risks in time,ensure public drug use safety,and promote clinical rational drug use.
林肖霞. 某院99例药品不良反应报告的回顾性分析[J]. 中国当代医药, 2020, 27(10): 189-192.
LIN Xiao-xia. Retrospective analysis of 99 adverse drug reaction reports in a hospital. 中国当代医药, 2020, 27(10): 189-192.
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