Abstract：Objective To explore the clinical characteristics of thyroid nodules with different nature in order to better evaluate the nature of thyroid nodules.Methods The data of 508 inpatients with surgical removal of thyroid nodules in our hospital from January to October,2013 were investigated,according to the pathological diagnosis,they were divided into benign group and malignant group.The gender,serum TSH level and ultrasonographic data were compared between the two groups.Results ①There were 508 patients with thyroid nodules,396 cases were benign patients,the average age was(46.26±12.25)years old,112 cases were malignant patients,the average age was(42.28±13.12)years old,and there was no significant difference in the average age between the two groups(P>0.05).In benign group (n=362),nodular goiter was the most common,accounting for 91.4%,while in malignant group (n=87),papillary carcinoma was the most common,accounting for 77.7%.The average age of patients with subacute thyroiditis was the smallest,and there was no significant difference in the mean age of other pathological types(P>0.05).The prevalence of thyroid nodules in women was higher than that in men (80.3%vs.19.7%)(P<0.05),and there was no significant difference between the two groups(P=0.798).②The serum thyroid stimulating hormone(TSH)level in malignant group was higher than that in benign group,but the difference was not statistically significant(P=0.891).③Comparing the thyroid ultrasonographic data of the two groups,the malignant group had more single,no cystic change,unclear boundary,low echo-level,solid nodules or solid+mixed nodules,fine calcification,cervical lymph node enlargement,and abundant blood supply in and around the cervical lymph nodes(P<0.01).Conclusion Thyroid nodules are mainly benign and it is frequently seen in women,high TSH and ultrasonography suggest that single,no cystic change,unclear boundary,low echo-level,solid nodules or solid+mixed nodules,fine calcification,cervical lymph node enlargement,and abundant blood supply in and around the cervical lymph nodes are more likely to be malignant nodules.
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LI Ya-qing;ZHANG Jia-jun. Analysis the clinical characteristics of thyroid nodules with different nature. 中国当代医药, 2018, 25(26): 18-21.
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