ObjectiveTo investigate the effect of group B Streptococcus (GBS)infection in late pregnancy on pregnant women and neonates.MethodsA total of 80 cases of pregnant women who received genitourinary tract examination in late pregnancy(28 weeks to the end of delivery)from October 2014 to October 2016 in our hospital were enrolled in the study.40 patients with positive results of CBS culture were included into the case group,and 40 normal pregnant women were selected as the healthy group.The postpartum hemorrhage,cesarean section,premature rupture of membranes,intrauterine infection and other adverse events were compared between the two groups,and the incidence rates of neonatal distress,infection and premature birth were recorded.ResultsAmong the 80 subjects,there were 40 cases of GBS infection.The incidence rate of postpartum hemorrhage,intrauterine infection and premature rupture of membranes were significantly higher in the case group than the healthy group (17.5%,27.5%,12.5%vs.2.5%,5.0%,0)the differences were statistically significant(P＜0.05).The incidence rate of fetal distress cases and infection were significantly higher in the case group than the healthy group(20.0%,17.5%vs.8.0%and 2.5%)(P＜0.05),but there was no significant difference in the incidence of preterm birth(P＞0.05).ConclusionGBS infection in late pregnancy can significantly increase the risks of premature rupture of membranes,intrauterine distress,infection and premature birth.Screening in late pregnancy should be strengthened and timely antimicrobial therapy should be carried out to avoid adverse pregnancy outcomes.