Effect of Extract of Ginkgo Biloba Leaves Tablets on hearing in patients with nasopharyngeal carcinoma undergoing radiotherapy
CHEN Hao-ying;ZHANG Long-cheng
Department of Otorhinolaryngology,Throat and Neck Surgery,the 303rdHospital of the Chinese People′s Liberation Army,Guangxi Zhuang Autonomous Region,Nanning 530021,China
Abstract:ObjectiveTo explore the effect of extract of Ginkgo Biloba Leaves Tablets on complications and hearing loss in nasopharyngeal carcinoma patients undergoing radiotherapy.Methods60 patients with nasopharyngeal carcinoma treated by radiotherapy were selected from December 2013 to December 2016,and they were randomly divided into the observation group and the control group,30 patients in each group.The two groups were given radiotherapy for nasopharyngeal carcinoma,while the observation group was treated with Extract of Ginkgo Biloba Leaves Tablets at the same time.The two groups were treated continuously for 3 months.The hearing loss in two groups were observed before and after radiotherapy.ResultsThe total effective rate of hearing improvement in observation group was higher than that in control group,the difference was statistically significant(P<0.05).The air conduction hearing threshold,middle ear pressure respectively in the observation group before radiotherapy were compare with those in the control group before radiotherapy,the difference was not statistically significant(P>0.05);the air conduction hearing threshold in the observation group after radiotherapy was lower than the control group after radiotherapy,the middle ear pressure pressure in the observation group after radiotherapy was higher than the control group after radiotherapy,the difference was statistically significant(P<0.05).ConclusionExtract of Ginkgo Biloba Leaves Tablets can reduce the degree of middle ear injury during nasopharyngeal carcinoma radiotherapy,and the effect is significant.