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Quick Search     Adv Search 2022 Vol. 29, No. 3 Published: 2022-01-28   4 Effect of Licorice Chalcone A on the proliferation and apoptosis of human glioma U251 cells WAN Shanshan； SUN Xiaodong； YAN Lei Objective To investigate the effect of Licorice Chalcone A on the proliferation and apoptosis of human glioma U251 cells.Methods Human glioma U251 cells cultured in vitro were divided into four groups (n=20).The control group was treated with the same amount of 0.9% NaCl,the low-dose Licorice Chalcone A group was treated with 15 μmol/L Licorice Chalcone A,the medium-dose Licorice Chalcone A group was treated with 30 μmol/L Licorice Chalcone A,the high-dose Licorice Chalcone A group was treated with 45 μmol/L Licorice Chalcone A.All were treated for 48 h.The cell proliferation levels of the four groups were detected by methyl thiazolyl tetrazolium colorimetry method.The expression levels of Wnt/β-catenin signaling pathway related proteins β-catenin and Cyclin D1 mRNA in the four groups were detected by real-time fluorescence quantification.The protein expression levels of proliferating nuclear antigen Ki-67 (Ki-67) and B lymphoma-2 (Bcl-2) in four groups were detected by Western blot.Results The cell proliferation levels,β-catenin mRNA,Cyclin D1 mRNA relative expression levels,Ki-67 and Bcl-2 in the lowdose Licorice Chalcone A group,the medium-dose Licorice Chalcone A group and the high-dose Licorice Chalcone A group were lower than those in the control group,the differences were statistically significant (P ＜0.01).The cell proliferation levels,β-catenin mRNA,Cyclin D1 mRNA relative expression levels,Ki-67 and Bcl-2 in the medium-dose Licorice Chalcone A group and the high-dose Licorice Chalcone A group were lower than those of the low-dose Licorice Chalcone A group,the differences were statistically significant (P＜0.01).The cell proliferation levels,β-catenin mRNA,Cyclin D1 mRNA relative expression levels,Ki-67 and Bcl-2 protein relative expression in the high-dose Licorice Chalcone A group were lower than those of the medium-dose Licorice Chalcone A group,and the differences were statistically significant (P＜0.01).Conclusion Licorice Chalcone A can inhibit the proliferation and promote apoptosis of human glioma U251 cells.The mechanism may be related to down-regulation of β-catenin mRNA,Cyclin D1 mRNA,Ki-67 and Bcl-2 expression levels. 2022 Vol. 29 (3): 4-7 [Abstract] ( 81 ) HTML (1 KB)  PDF (597 KB)  ( 93 ) 8 Changes and clinical significance of arterial blood lactic acid and biochemical factors in amniotic fluid contaminated with neonatal asphyxia HUANG Shengcai； QU Liyan；HUANG Chao； HE Jiang；AI Jianjun； HU Hai； LI Haiyan Objective To explore and analyze the changes and clinical significance of arterial blood lactic acid and biochemical factors in amniotic fluid contaminated with neonatal asphyxia.Methods From March 2017 to March 2021,120 neonates with amniotic fluid pollution admitted to the Department of Obstetrics and Gynecology and Department of Neonatology in Fuzhou Maternal and Child Health Hospital were selected as the research objects,and they were divided into Ⅰdegree pollution group (43 cases) and Ⅱdegree pollution group (40 cases) and Ⅲdegree pollution group (37 cases) according to the degree of amniotic fluid pollution.A total of 38 cases with neonatal asphyxia were divided into mild asphyxia group (25 cases) and severe asphyxia group (13 cases) according to the degree of asphyxia,and the rest were non-asphyxia group (82 cases).Another 45 neonates without amniotic fluid contamination were selected as the control group.The levels of arterial blood lactic acid and biochemical factors in different amniotic fluid contaminated group and control group were compared.The correlation between the degree of amniotic fluid contamination and arterial blood lactic acid was analyzed.The incidence of neonatal asphyxia in different amniotic fluid contaminated groups was compared.The arterial blood lactic acid levels of neonates in different asphyxia groups were compared at different time after birth.Results The lactic acid values of umbilical artery blood in the Ⅰdegree pollution group,Ⅱdegree pollution group and Ⅲdegree pollution group were higher than those of the control group,the umbilical artery blood lactic acid values in the Ⅱdegree pollution group,Ⅲdegree pollution group were higher than Ⅰdegree pollution group,the lactic acid value of the umbilical artery in the Ⅲdegree pollution group was higher than that in the Ⅱdegree pollution group,and the differences were statistically significant (P＜0.05).Pearson correlation analysis showed that the degree of amniotic fluid pollution was positively correlated with arterial lactic acid level (P＜0.05).The total asphyxiation rate of the Ⅲdegree pollution group was higher than that of the Ⅰdegree pollution group and theⅡdegree pollution group,and the differences were statistically significant (P＜0.05).The arterial blood lactic acid values of the three groups 24 h after birth were lower than those at birth,6,12 h after birth,the arterial blood lactic acid values of the three groups 12 h after birth were lower than those at birth,6 h after birth,the arterial blood lactic acid values of the three groups 6 h after birth were lower than those at birth,and the differences were statistically significant (P＜0.05).The arterial blood lactic acid values of neonates in the severe asphyxia group and mild asphyxia group at birth,6,12,24 h after birth were higher than those of the non-asphyxia group,the arterial blood lactic acid values of neonates in the severe asphyxia group at birth,6,12,24 h after birth were higher than those of the mild asphyxia group,and the differences were statistically significant (P＜0.05).Conclusion As the degree of amniotic fluid pollution increases,the umbilical artery blood lactate value also increases.The incidence of neonatal asphyxia is closely related to the degree of amniotic fluid pollution.The more severe the amniotic fluid pollution,the greater the neonatal asphyxia rate. 2022 Vol. 29 (3): 8-12 [Abstract] ( 90 ) HTML (1 KB)  PDF (549 KB)  ( 65 ) 13 Application effect of Dingkundan in adjuvant treatment of infertile patients with ovarian endometriosis cyst after laparoscopic surgery LI Yili ；HE Zhilan Objective To investigate the application effect of Dingkundan in the adjuvant treatment of infertility patients with ovarian endometriosis cyst after laparoscopic surgery.Methods From March 2018 to March 2020,84 infertile patients with ovarian endometriosis cyst treated by laparoscopic surgery in Dongguan Guangji Hospital were selected as the research objects,and they were divided into control group (42 cases) and observation group (42 cases) by simple randomization.The control group was treated with injection of Triptorelin,while the observation group was treated with Dingkundan on the basis of Triptorelin.The quantitative score of clinical symptom severity was compared between the two groups.At the same time,the follicular growth rate after ovulation,the level of estradiol on ovulation day,the incidence of complications,recurrence rate and pregnancy rate of the two groups were compared.Results After treatment,the quantitative severity scores (including primary and secondary symptoms) of the two groups were lower than before treatment,and the differences were statistically significant (P＜0.05).There were no significant differences in pregnancy rate and recurrence rate between the two groups (P＞0.05),and the incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).The follicle growth rate of the observation group was faster than that of the control group,and the difference was statistically significant (P＜0.05).There was no significant difference in estradiol value at follicular maturation between the two groups (P＞0.05).Conclusion Dingkundan adjuvant treatment of ovarian endometriosis cyst infertility patients after laparoscopic surgery can effectively reduce the pain and menopausal symptoms,increase the pregnancy rate,and reduce the recurrence rate and the incidence of complications. 2022 Vol. 29 (3): 13-16 [Abstract] ( 95 ) HTML (1 KB)  PDF (540 KB)  ( 36 ) 17 Clinical effect of antiplatelet combined with anticoagulant in the treatment of coronary heart disease complicated with lower limb arterial occlusion BAI Sen Objective To investigate the clinical effect of antiplatelet combined with anticoagulant drugs on patients with coronary heart disease complicated with lower limb artery occlusion.Methods A total of 104 patients with coronary heart disease combined with treatment in hospitalization in Fushun City Hospital of Traditional Chinese Medicine from January 2019 to December 2020.According to random number table method,they were divided into monoclonal antibody group (n=52) and double antibody group (n=52).Both groups received routine examination and basic treatment after admission.In addition to the basic treatment,the monoclonal antibody group was given Aspirin enteric-coated tablet,and the double antibody group was given Rivaroxaban tablet in addition to the monoclonal antibody group.The intervention lasted for 8 weeks in both groups.The Seattle Scale (SAQ) score,treatment effect of lower extremity arteriosclastic oblusion,quality of life score (SF-36),ankle-brachial index (ABI),activated partial thrombin time (APTT),prothrombin time (PT) and platelet (PLT) were compared between two groups before and after treatment.Results There was no significant difference in SAQ score between the two groups before and after treatment (P＞0.05).There was no significant difference in ABI between the two groups before treatment (P＞0.05).After treatment,the ABI of the two groups was higher than before,and the ABI of the double antibody group was higher than that of the monoclonal antibody group,the differences were statistically significant (P＜0.05).There was no significant difference in SF-36 score before treatment (P＞0.05).After treatment,the SF-36 score of the two groups were higher than those before treatment,and the SF-36 score of the double antibody group was higher than that of the monoclonal antibody group,the differences were statistically significant (P＜0.05).There were no significant differences in APTT,PT and PLT between two groups before and after treatment (P＞0.05).Conclusion Aspirin combined with Rivaroxaban treatment of coronary heart disease combined with lower extremity arteriosclerosis can be brought to thrombin to form a thrombosis,thereby improving the treatment of patients to improve the patient′s ABI level. 2022 Vol. 29 (3): 17-20转24 [Abstract] ( 78 ) HTML (1 KB)  PDF (575 KB)  ( 65 ) 21 Research progress on the relationship between IL-37 and clinical diseases ZOU Chenxi ；ZENG Ji ；FAN Fanghua ；LI Yimeng； LIU Jing ；WANG Qi Interleukin-37 (IL-37),a member of the interleukin-1 family,is a novel inflammatory suppressor with negative feedback regulation.It is mainly derived from epithelial cells,monocytes and macrophages and can be expressed in many normal tissues,it is closely related to tumor and inflammation in clinic.By reducing the expression of Proinflammatory cytokine and chemokines and increasing the expression of immunosuppressive factors,IL-37 has a significant regulatory effect on a variety of inflammatory and immune related diseases,and by inhibiting angiogenesis,inhibition of tumor proliferation,Migration,so as to play an anti-tumor role.Clinical application of IL-37 can diagnose disease,monitor the progress of disease and control the occurrence and development of disease. 2022 Vol. 29 (3): 21-24 [Abstract] ( 85 ) HTML (1 KB)  PDF (463 KB)  ( 76 ) 25 Research progress of rehabilitation treatment of dysphagia after stroke with traditional Chinese and Western medicine LONG Ruiju ；SHI Guofeng； ZHAO Jinju ；LEI Piao； SU Shanshan Stroke is characterized by high morbidity,high mortality,high recurrence rate,high disability rate and rapid disease progression,becoming the top cause of death and disability among Chinese adults.Multiple complications may occur after stroke,and dysphagia is one of the most common complications.After stroke patients with dysphagia due to restricted eating will cause dehydration,malnutrition,electrolyte disorder and aspiration pneumonia and other adverse consequences,seriously affect the quality of life of patients,delay the process of disease recovery,increase the economic burden of family and society.There are many methods for the treatment of dysphagia after stroke,but there is still a lack of specific treatment methods.In clinical practice,swallowing training,swallowing function training,electrical stimulation therapy,nerve regulation technology,catheter balloon dilation,acupuncture therapy,traditional Chinese medicine therapy,acupoint massage and other methods are used to improve the swallowing function.This paper discusses the understanding of dysphagia after stroke from modern medicine and traditional medicine,and summarizes the rehabilitation methods of Chinese and Western medicine for dysphagia after stroke,in order to provide reference for clinical selection of rehabilitation treatment programs. 2022 Vol. 29 (3): 25-29 [Abstract] ( 64 ) HTML (1 KB)  PDF (492 KB)  ( 105 ) 30 Analysis of the factors affecting noninvasive mechanical ventilation failure in patients with acute left heart failure WANG Bo ；DONG Li ；ZHU Zhuozhen ；WU Xianqiu Objective To explore the influencing factors of noninvasive mechanical ventilation failure in patients with acute left heart failure.Methods A total of 90 patients admitted to the General Hospital of Pingxiang Mining Group Co.,Ltd from January 2019 to December 2020 were selected and were divided into good treatment group (47 cases) and treatment failure group (43 cases) according to the treatment effect.Basic clinical data of both groups were counted and underwent univariate analysis,multivariate and statistically significant factors were analyzed for logistic regression to screen for independent risk factors.Results The univariate analysis results showed that air mask leakage,facial compression injury,abdominal distension,improper use method,occurrence of metabolic complications,pH,neutrophils as the percentage of leukocytes were related factors affecting the failure of non-invasive mechanical ventilation (P＜0.05).The multivariate regression analysis showed that mask leakage,facial compression injury,abdominal distension,improper use,and metabolic complications were independent risk factors for poor noninvasive mechanical ventilation failure in acute left heart failure (P＜0.05).Conclusion Air mask leakage,facial compression injury,abdominal distension,improper use methods,and metabolic complications are all the influencing factors of noninvasive mechanical ventilation failure in patients with acute left heart failure.Clinically,early risk assessment and prevention of the influencing factors are needed to improve the treatment effect. 2022 Vol. 29 (3): 30-32转36 [Abstract] ( 76 ) HTML (1 KB)  PDF (755 KB)  ( 33 ) 33 Quality evaluation of cryoprecipitation with different capacity prepared by automatic blood component separator WANG Wei ；CHAI Tingting； ZHANG Xuesong； LI Yunqiang ；LIU Xiangjun Objective To evaluate the quality of cryoprecipitation with different volumes prepared by the automatic blood component separator.Methods A total of 60 bags of 400 ml qualified blood collected in Changchun Central Blood Station from January 2019 to April 2020 were selected.Fresh frozen plasma was prepared according to standard operating procedures,and cryoprecipitated coagulation factors were prepared by automatic blood component separator.According to the final product volume of coagulation factor,they were divided into groups A and B,group A: 20-30 ml,30 bags;group B: 40-50 ml,30 bags.The cryoprecipitate capacity,Ⅷfactor content and fibrinogen content were compared between the two groups.Results The volume of group A ([29.73±0.74] ml/bag) was lower than that of group B ([44.57±2.80] ml/bag),and the difference was statistically significant (P＜0.001).There were no statistically significant differences in Ⅷfactor content ([103.78±15.06] U/bag) and fibrinogen content ([289.60±58.72] mg/bag) between group A and group B ([104.68±24.42] U/bag,[296.70±55.29] mg/bag) (P＞0.05).Conclusion The automatic blood component separator is used to prepare cryoprecipitation with different capacities.There is no difference in the quality of cryoprecipitation between the two groups,which meets the national standards.This preparation method is worth promoting. 2022 Vol. 29 (3): 33-36 [Abstract] ( 54 ) HTML (1 KB)  PDF (790 KB)  ( 19 ) 37 Clinical effect of Tripterygium Glycoside Tablets in treating Sjogren′s syndrome JU Yanjuan； LI Rongping；ZHOU Shenghui；HU Jin；GUO Dibin Objective To explore the clinical effect of Tripterygium Glycoside Tablets in the treatment of Sjogren′s syndrome.Methods From January 2020 to May 2021,60 patients with Sjogren′s syndrome admitted to the First Affiliated Hospital of Gannan Medical College were selected as the research objects,and they were divided into the control group (30 cases) and the observation group (30 cases) according to the random number table method.The control group was treated with Prednisone+Hydroxychloroquine Sulfate,and the observation group was treated with Tripterygium Glycoside Tablets.The clinical efficacy,the levels of immunoglobulin,rheumatoid factor,improvement of clinical symptoms,and the incidence of adverse reactions between the two groups were compared.Results The clinical efficacy of the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).After treatment,the levels of IgG and rheumatoid factor (RF) in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).The saliva flow rate and tear flow rate of the observation group were higher than those of the control group,and the numerical evaluation scale (NRS) score of the observation group was lower than that of the control group,the differences were statistically significant (P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Tripterygium Glycoside Tablets are effective in treating Sjogren′s syndrome.They can effectively improve the symptoms of dry mouth,dry eyes,and joint pain,as well as immune function and rheumatoid factor levels. 2022 Vol. 29 (3): 37-39 [Abstract] ( 71 ) HTML (1 KB)  PDF (786 KB)  ( 80 ) 40 Analysis ofnutritional status in different group patients with chronic obstructive pulmonary disease in stable stage YU Jie ；LUO Linlin； LI Yunxia ；GUO Youdan Objective Discussion on the difference in nutrition indicators of various groups of chronic obstructive pulmonary disease (COPD) Global Initiative guidelines (GOLD) in patients with COPD in stable stage.Methods From January 2018 to December 2020,160 stable COPD patients who were in the Department of Outpatient of Jiangxi Provincial People′s Hospital were selected as subjects.According to GOLD guidelines,stable COPD patients were divided into groups A,B,C and D,with 40 cases in each group.Forty healthy adults at the same time were selected as control group.The serum total protein (TP),albumin,creatinine (Cre) and urea nitrogen (BUN) in five groups were compared.Results The serum TP and albumin in COPD stable stage patients in groups A,B,C and D were lower than those in healthy control group,and Cre levels were higher than those in healthy control group,the differences were statistically significant (P＜0.05).There was no significant difference in serum BUN level between groups A,B,C and D and control group (P＞0.05).There were no statistical significance in serum TP,Cre and BUN in groups A,B,C and D(P＞0.05),and there were no statistical significance in serum albumin in groups A,B and C (P＞0.05).The serum albumin level in group D was lower than that in groups A,B and C,and the difference was statistically significant (P＜0.05).Conclusion Serum albumin can be used as an important indicator of the stable stage of COPD patients with high risk of acute exacerbation and severity symptoms in the future,and needs high vigilance in clinic practice,timely intervention treatment may reduce acute exacerbation,improve the clinical symptoms of patients. 2022 Vol. 29 (3): 40-43 [Abstract] ( 64 ) HTML (1 KB)  PDF (748 KB)  ( 38 ) 44 Effect of continuous nursing by intelligent remote system on the mental state and self-management ability of patients with high-risk Human Papilloma Virus infection REN Jia； ZHOU Lizhu ；CAI Chunfang Objective To explore the application effect of continuous nursing by intelligent remote system in patients with high-risk Human Papilloma Virus (HPV) infection.Methods A total of 106 patients with high-risk HPV infection who were admitted to Guangzhou Women and Children′s Medical Center from December 2019 to November 2020 were selected as the research subjects,and they were divided into a control group (n=53) and an observation group (n=53) by random number table method.The patients in the control group were received routine intervention,and in the observation group,they received continuous care by the intelligent remote system for three months of intervention.The mental state,self-management ability and nursing satisfaction were compared between the two groups.Results The total nursing satisfaction of the observation group was 96.23%,higher than that of the control group of 84.91%,the difference was statistically significant (P＜0.05).After intervention,the scores of self-rating anxiety scale (SAS) and self-rating depression scale (SDS) in the observation group were lower than those in the control group,and the scores of exercise of self-care agency scale (ESCA) were higher than those in the control group,with statistical significances (P＜0.05).Conclusion The continuous nursing by the intelligent remote system can reduce the negative emotions of patients with high-risk HPV infection,improve the self-management ability of patients,and increase nursing satisfaction. 2022 Vol. 29 (3): 44-47 [Abstract] ( 73 ) HTML (1 KB)  PDF (783 KB)  ( 46 ) 48 Clinical application effect of the modified midline catheter HU Linai1；XU Yuehong； ZHANG Huilan；WAN Xiaofang；XU Yueyuan Objective To explore the clinical application effect of the modified midline catheter.Methods A total of 125 patients required infusion of stimulating vascular drugs admitted to Yingtan People′s Hospital from January 2019 to October 2020 were selected retrospectively selected,and divided into four groups in the central venous catheter (PICC)group (25 cases),central venous catheter (CVC) group (25 cases),peripheral indwelling needle (PVC) group (37 cases),and midline catheter (MC) group (38 cases).The MC group had mechanical lebitis,mechanical phlebitis,drug extravasation,catheter-related infections,catheter-related thrombosis,and one-time puncture success rates were compared with the other three groups.Results The overall incidence of complications in the MC group was lower than that in the PICC group,CVC group,and PVC group,with statistically significant difference (P＜0.05).The incidence of mechanical phlebitis in the MC group was lower than that in the PICC group and PVC group,and the difference was statistically significant (P＜0.05).The incidence of mechanical phlebitis between the MC group and CVC group with no significant difference (P＞0.05).The incidence of drug extravasation in MC group was lower than that in PVC group,and the difference was statistically significant (P＜0.05).The incidence of catheter-associated infection in the MC group was lower than that in the CVC group,and the difference was statistically significant (P＜0.05).The incidence of catheter-associated thrombosis in the MC group was lower than that in the PVC group,and the difference was statistically significant(P＜0.05).The success rate of one-time puncture in the MC group was higher than that in the PICC group,CVC group and PVC group,and the difference was statistically significant (P＜0.05).Conclusion The modified midline catheter has the advantages of relatively simple operation,small trauma and less complications,and has good clinical application prospects,and is worth clinical promotion and application. 2022 Vol. 29 (3): 48-51 [Abstract] ( 67 ) HTML (1 KB)  PDF (788 KB)  ( 179 ) 52 Effect of noninvasive ventilator intermittent positive pressure breathing therapy on blood gas index and ventilation in patients with chronic obstructive pulmonary disease and respiratory failure ZHU Xiaorong Objective To analyze the effect of noninvasive ventilator intermittent positive pressure breathing therapy on blood gas index and ventilation in patients with chronic obstructive pulmonary disease and respiratory failure.Methods A total of 84 patients with chronic obstructive pulmonary disease and respiratory failure admitted to Ganzhou Fifth People′s Hospital from February 2019 to October 2020 were selected as the research objects.They were randomly divided into the control group and the observation group,with 42 cases in each group.The control group was treated with conventional noninvasive ventilator continuous ventilation,and the observation group was treated with noninvasive ventilator intermittent positive pressure breathing therapy.The blood gas index,complications and cardiac function of the two groups were compared.Results There were no statistically significances in blood gas indexes between the two groups before treatment (P＞0.05).After treatment,the partial pressure of oxygen (PaO2) and oxygen saturation (SaO2) in the two groups were higher than those before treatment,and partial pressure of carbon dioxide (PaCO2) in the arterial blood in the two groups were lower than those before treatment,the differences were statistically significant (P＜0.05).After treatment,PaO2 and SaO2 in the observation group were higher than those in the control group,and PaCO2 was lower than that in the control group,the differences were statistically significant (P＜0.05).There were no statistically significances in cardiac function indexes between the two groups before treatment (P＞0.05).After treatment,the left ventricular ejection fraction (LVEF) of the two groups were higher than those before treatment,and the brain natriuretic peptide(BNP) was lower than that before treatment,the differences were statistically significant (P＜0.05).The LVEF of the observation group after treatment was higher than that of the control group,and the BNP was lower than that of the control group,the differences were statistically significant(P＜0.05).The complication rate of the observation group was lower than that of the control group,the difference was statistically significant (P＜0.05).Conclusion For patients with chronic obstructive pulmonary disease and respiratory failure,noninvasive ventilator intermittent positive pressure breathing therapy can not only improve the blood gas index,but also improve the cardiac function,and effectively control the complications. 2022 Vol. 29 (3): 52-55 [Abstract] ( 57 ) HTML (1 KB)  PDF (744 KB)  ( 41 ) 56 Clinical effect of Lemon Essential Oil in preventing respiratory tract infection after abdominal tracheal intubation under general anesthesia ZHANG Ling ；ZHU Jinxiang； WANG Miao； FU Rong； JIA Hui Objective To explore the clinical effect of Lemon Essential Oil on the prevention of respiratory tract infections after abdominal tracheal intubation under general anesthesia.Methods A total of 408 patients undergoing abdominal gynecological surgery under elective intubation under general anesthesia in the First People′s Hospital of Changde City from April 2020 to December 2020 were selected as the research objects,they were divided into the Milian Pei Pa Koa group (136 cases),Lemon Essential Oil sublingual group (137 cases),Lemon Essential Oil spray group (135 cases) by using a random number table methods.The Milian Pei Pa Koa group was given Milian Pei Pa Koa containing,and the Lemon Essential Oil sublingual group was given the diluted Lemon Essential Oil containing,and the Lemon Essential Oil spray group was given the diluted Lemon Essential Oil spraying.The protective effect of respiratory tract infections after abdominal tracheal intubation under general anesthesia,relief of respiratory symptoms,pathogenic bacteria types and colony counts of respiratory secretions among the three groups of patients were compared.Results The protective effect of respiratory tract infections after abdominal tracheal intubation under general anesthesia of the Lemon Essential Oil sublingual group and the Lemon Essential Oil spray group were higher than those of the Milian Pei Pa Koa group,and the differences were statistically significant (P＜0.017).The relief of symptoms of throat discomfort on the 2nd,the 3rd and the 4th day of preventive treatment in the Lemon Essential Oil sublingual group were better than those in the the Milian Pei Pa Koa group,the relief of symptoms of cough and sputum,cough difficulty on the 3rd and the 4th day of preventive treatment in the Lemon Essential Oil sublingual group were better than those in the Milian Pei Pa Koa group,with statistical significance (P＜0.017).The relief of symptoms of throat discomfort on the 3rd and the 4th day of preventive treatment in the Lemon Essential Oil spray group were better than those in the Milian Pei Pa Koa group,the relief of symptoms of cough and sputum,cough difficulty on the 4th day of preventive treatment in the Lemon Essential Oil spray group were better than those in the Milian Pei Pa Koa group,with statistical significance (P＜0.017).The count of pathogenic bacteria in respiratory secretions after preventive treatment in the Lemon Essential Oil sublingual group and the Lemon Essential Oil spray group were lower than those in the Milian Pei Pa Koa group,with statistical significance(P＜0.05).There were no significant differences in protective effect of respiratory tract infections after abdominal tracheal intubation under general anesthesia,respiratory symptom relief,pathogenic bacteria species and colony count in respiratory secretions between the Lemon Essential Oil sublingual group and the Lemon Essential Oil spray group (P＞0.05).Conclusion Both Lemon Essential Oil sublingual and spray can effectively prevent respiratory tract infections after abdominal tracheal intubation under general anesthesia and significantly improve symptoms of respiratory tract infections. 2022 Vol. 29 (3): 56-62 [Abstract] ( 69 ) HTML (1 KB)  PDF (808 KB)  ( 89 ) 63 Effect of enhanced recovery after surgery on the function of knee Anterior Cruciate Ligament reconstruction GUO Baozhen； DU Jinnan ；WANG Lihua Objective To evaluate the clinical efficacy of the concept of accelerating rehabilitation in the perioperative period after anterior cruciate ligament (ACL) reconstruction of the knee.Methods A total of 60 patients with anterior cruciate ligament injury arranging for anterior cruciate ligament reconstruction in Dongguan Kanghua Hospital from June 2017 to June 2018 were selected and divided into rehabilitation group and enhanced recovery after surgery(ERAS) group according to the random number table method,with 30 cases in each group.The traditional rehabilitation group was given routine rehabilitation measures,and the ERAS group was implemented with ERAS concept during perioperative period.All patients had the same chief physician to complete the operation.and recorded changes in visual analogue score ( VAS ) before surgery and 3,12,24,28,72 h after surgery.The time required for knee flexion at 30°,60°,90° and 120° was recorded,and the time required for knee flexion of 30°,60°,90°and 120°after the surgery;recorded the stays of hospitalization of patients and the changes in Lysholm function scores before,and 1,3,6,and 12 mouths after surgery.Results The VAS score at 3,12,24,28 and 72 h in ERAS group were lower than those in traditional rehabilitation group,the differences were statistically significant (P＜0.05).The postoperative knee flexion time of 30°,60°,90° and 120° and the length of hospital stay were shorter in ERAS group than in traditional rehabilitation group,with statistically significant differences (P＜0.05).The Lysholm function score of ERAS group at 1,3 and 6 months after surgery were higher than those of the traditional rehabilitation group,with statistical significances (P＜0.05).There was no significant difference in Lysholm function score between the two groups 12 months after surgery (P＞0.05).Conclusion Using the concept of ERAS to intervene in the perioperative period of knee anterior cruciate ligament (ACL)reconstruction can effectly reduce postoperative pain,shorten the length of hospital stays,accelerate the rehabilitation of affected limbs,and quickly restore knee function. 2022 Vol. 29 (3): 63-66 [Abstract] ( 80 ) HTML (1 KB)  PDF (793 KB)  ( 52 ) 67 Influence of aromatherapy on psychological distress,nausea and vomiting in patients undergoing chemotherapy for cancer GUO Xiaofeng； ZHU Juan； CHEN Ying Objective To explore the influence of aromatherapy on psychological distress,nausea and vomiting in patients undergoing chemotherapy for cancer.Methods A total of 120 chemotherapy patients diagnosed and treated in Department of Integrated Traditional Chinese and Western Medicine of Fujian Cancer Hospital from February 2019 to June 2020 were used as the research objects.They were divided into the research group (60 cases) and the control group (60 cases) according to the random number table method.The control group adopted conventional nursing measures,and the research group was given aromatherapy based on conventional nursing care.The distress thermometer(DT) and the National Cancer Institute′s Common Terminology Criteria for Adverse Event (NCI-CTCAE) version 4.0 were used to evaluate the patient′s psychological distress,nausea and vomiting on the 1 day before chemotherapy and 1st,3rd,and 5th days after chemotherapy between the two groups.Results There was no statistically significant difference DT score,the grade of nausea and vomiting between the two groups of patients before chemotherapy (P＞0.05).The DT score,the grade of nausea and vomiting of the research group on the 1st,3rd,and 5th days after chemotherapy were lower than those of the control group,the differences were statistically significant (P＜0.05).Conclusion Aromatherapy can reduce the psychological distress of cancer patients undergoing chemotherapy and prevent nausea and vomiting after chemotherapy. 2022 Vol. 29 (3): 67-70 [Abstract] ( 64 ) HTML (1 KB)  PDF (748 KB)  ( 171 ) 71 Effect of Esomeprazole combined with Trimebutine Maleate in the treatment of geriatric gastroesophageal reflux disease CHEN Chuantie； ZENG Xiaohui Objective To explore the effect of Esomeprazole combined with Trimebutin Maleate in the treatment of geriatric gastroesophageal reflux disease.Methods A total of 84 patients with geriatric gastroesophageal reflux disease admitted to Longgang Central Hospital of Shenzhen City from February 2018 to February 2020 were selected as the research subjects,and they were divided into the study group (42 cases) and the control group (42 cases) according to random number table method.The study group was treated with Esomeprazole combined with Trimebutin Maleate,while the control group was treated with Esomeprazole monotherapy.Both groups were treated for 8 weeks.Symptom score,quality of life score,gastroscopic efficacy,the level of serum motilin and gastrin-17 were compared between the two groups before and after treatment.Results There were no statistical significance in the symptom scores and quality of life scores of the two groups before treatment (P＞0.05).After treatment,symptom score of the two groups were lower than those before treatment,quality of life score of the two groups were higher than those before treatment,and the symptom score of the study group was lower than the control group,quality of life score of the study group was higher than the control group,the differences were statistically significant (P＜0.05).After treatment,the total effective rate under gastroscopy in the study group was higher than that in the control group,the difference was statistically significant(P＜0.05).Before treatment,there were no significant differences in the levels of serum motilin and serum gastrin-17 between the two groups (P＞0.05).After treatment,the levels of serum motilin in the two groups were higher than those before treatment,and the levels of serum gastrin-17 in the two groups were lower than those before treatment,and the level of serum motilin in the study group was higher than that in the control group,and the level of serum gastrin-17 in the study group was lower than that in the control group,the differences were statistically significant (P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Esomeprazole combined with Trimebutin Maleate in the treatment of geriatric gastroesophageal reflux disease is effective,which can effectively improve the clinical symptoms,improve the quality of life. 2022 Vol. 29 (3): 71-73转77 [Abstract] ( 69 ) HTML (1 KB)  PDF (759 KB)  ( 109 ) 74 Comparison of the clinical effect of Clopidogrel and Ticagrelor in the treatment of acute myocardial infarction JIAO Qi Objective To explore the clinical effects of Clopidogrel and Ticagrelor in the treatment of acute myocardial infarction.Methods Eighty patients with acute myocardial infarction who underwent percutaneous coronary intervention(PCI) admitted to the Iron Coal General Hospital of Liaoning Health Industry Group from January 2019 to January 2020 were selected as the research subjects.They were divided into observation group and control group according to random number table method,with 40 cases in each group.The patients in the observation group were treated with Ticagrelor and the patients in the control group were treated with Clopidogrel.The platelet count,platelet aggregation rate,maximum aggregation time of adenosine diphosphate(ADP),maximum aggregation rate of ADP,cardiac function and total incidence of complications of two groups were compared.Results The platelet count and platelet aggregation rate in the observation group after treatment were lower than those in the control group,while the maximum aggregation time of ADP was longer than that in the control group,the maximum aggregation rate of ADP was higher than that in the control group,the differences were statistically significant (P＜0.05).After treatment,the cardiac function of the two groups was better than that before treatment,and the cardiac function of the observation group was better than that of the control group,the differences were statistically significant (P＜0.05).The total incidence of complications of patients during the treatment period in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Compared with Clopidogrel,Ticagrelor has a better clinical effect in the treatment of acute myocardial infarction.It can improve the cardiac function of patients with high safety,and is worthy of promotion. 2022 Vol. 29 (3): 74-77 [Abstract] ( 67 ) HTML (1 KB)  PDF (743 KB)  ( 26 ) 78 Effect observation of wax therapy combined with Mecobalamin in the treatment of peripheral neurotoxicity caused by Albumin-Bound Paclitaxel LI Wen； MI Yuling ；CHENG Fang ；XI Xiaoming Objective To explore the effect of wax therapy combined with Mecobalamin in the treatment of peripheral neurotoxicity caused by Albumin-Bound Paclitaxel.Methods A total of 98 patients with Albumin-Bound Paclitaxelinduced peripheral neurotoxicity admitted to Chaoyang District Third Ring Tumor Hospital,Beijing from January 2019 to December 2020 were selected as the study subjects.According to random number table method,the patients were divided into monotherapy group (49 cases) and combination group (49 cases).The monotherapy group was treated with Mecobalamine Tablets,and the combination group was treated with Mecobalamine Tablets combined with wax therapy.The therapeutic effect,sensory nerve conduction velocity (SNCV) and motor nerve conduction velocity (MNCV),pain degree and safety were compared between the two groups.Results The total effective rate of combination group was higher than that of monotherapy group,and the difference was statistically significant (P＜0.05).MNCV,SNCV median nerve conduction velocity and peroneal nerve conduction velocity in the combination group were higher than those in the monotherapy group,the differences were statistically significant (P＜0.05).The degree of pain after treatment in the combination group was lower than that in the monotherapy group,and the difference was statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion The combination of wax therapy and Mecobalamin has a significant effect on peripheral neurotoxicity caused by Albumin-Bound Paclitaxel.It can speed up nerve conduction,relieve pain,and has fewer adverse reactions,which has the value of popularization and application. 2022 Vol. 29 (3): 78-81 [Abstract] ( 78 ) HTML (1 KB)  PDF (436 KB)  ( 45 ) 82 Application effect of Pyrorubicin and Docetaxel combined with neoadjuvant chemotherapy in young breast cancer patients CAO Dan Objective To investigate the efficacy of Pyrorubicin and Docetaxel combined with neoadjuvant chemotherapy in young breast cancer,and the effect on prognosis,expression of cancer tissue proliferative nuclear antigen Ki-67(Ki-67),human epidermal growth factor receptor(Her-2)and vascular endothelial growth factor(VEGF)in cancer tissues.Methods A total of 90 young breast cancer patients admitted to Tieling Central Hospital from January 2015 to August 2017 were selected as research subjects.They were divided into combined group and control group by computer random number table method,with 45 cases in each group.The control group received Docetaxel chemotherapy,while the combined group received Pyrorubicin and Docetaxel combined with neoadjuvant chemotherapy.The clinical efficacy of the two groups was compared.The expressions of Ki-67,Her-2,VEGF and the levels of T lymphocyte subsets (CD3+,CD4+,CD8+,CD4+/CD8+) of patients in the two groups before and after treatment were compared.The prognosis (3-year disease-free survival rate [DFS],overall survival period [OS]) of patients in the two groups was compared.Results The total effective rate in combined group was higher than that in control group,the difference was statistically significant(P＜0.05).The positive rates of Ki-67 and VEGF in the combined group were 22.22% and 37.78%,respectively,lower than 51.11% and 62.22% in the control group,with statistical significances (P＜0.05).There was no significant difference in the positive rate of Her-2 between the two groups after treatment (P＞0.05).The 3-year DFS and OS of the combined group were 93.33% and 97.78%,respectively,which were higher than those of the control group of 73.33%and 82.22%,respectively,the differences were statistically significant (P＜0.05).There were no significant differences in the levels of various T lymphocyte subsets before treatment between the two groups (P＞0.05).After treatment,CD3+,CD4+,CD4+/CD8+ were lower than those before treatment,while CD8+ level was higher than that before treatment,the differences were statistically significant (P＜0.05).After treatment,CD3+,CD4+and CD4+/CD8+in combined group were higher than those in control group,while CD8+ was lower than that in control group,the differences were statistically significant (P＜0.05).Conclusions The Pyrorubicin and Docetaxel combined with neoadjuvant chemotherapy in young breast cancer patients can achieve ideal short-term efficacy and prognosis,and can reduce the expression levels of Ki-67 and VEGF to a certain extent,and enhance the immune function of the body. 2022 Vol. 29 (3): 82-85 [Abstract] ( 63 ) HTML (1 KB)  PDF (443 KB)  ( 100 ) 86 Comparative study on the application of two-dimensional and three-dimensional ultrasound in the diagnosis and treatment of infant DDH XU Shanshan ；QIU Qingjun； DAI Hongwei ；ZHOU Bin Objective To study the application value of two-dimensional ultrasound and three-dimensional ultrasound in the diagnosis and treatment of development dysplasia of hip (DDH) in infants.Methods A total of 30 children with clinically suspected DDH were selected between March 2019 and April 2020 in Shangrao Municipal Hospital.All children received two-dimensional and three-dimensional ultrasound hip examinations.The examination time of two-dimensional ultrasound and three-dimensional ultrasound,examination compliance of children,and consistency of twodimensional ultrasound and three-dimensional ultrasound were compared.Results The examination time of the two groups of children with three-dimensional ultrasound were shorter than those of two-dimensional ultrasound,and the differences were statistically significant (P＜0.05).The compliance of the two groups of children with three-dimensional ultrasound were higher than those of two-dimensional ultrasound,and the differences were statistically significant (P＜0.05).Two-dimensional ultrasound diagnosis sensitivity was 68.42%,specificity was 90.91%,accuracy rate was 76.67%,positive predictive value was 92.86%,negative predictive value was 62.50%,Kappa value was 0.541.Threedimensional ultrasound diagnosis sensitive degree was 84.21%,specificity was 90.91%,accuracy rate was 86.67%,positive predictive value was 94.11%,negative predictive value was 76.92%,Kappa value was 0.724.Conclusion Threedimensional ultrasound can shorten the examination time and observe the condition of hip joint more accurately.It can be used as a routine examination method. 2022 Vol. 29 (3): 86-88 [Abstract] ( 61 ) HTML (1 KB)  PDF (494 KB)  ( 100 ) 89 Application of 3D laparoscopy in gynecological uterine fibroids surgery ZHANG Xiaocui； CHEN Weitao； FU Zhiqing； YANG Ziying； YU Jidong； XU Yanmiao Objective To explore the application effect of 3D laparoscopy on gynecological uterine fibroids surgery.Methods A total of 60 patients with uterine fibroids treated in Shangrao people′s Hospital from May 2018 to July 2019 were selected as the research object.The random number table method was used to divide 30 cases into the control group and 30 cases in the observation group.The control group used traditional 2D laparoscopic surgery,and the study group used 3D laparoscopic technology.The operation time,first exhaust time,time of hospital stay and intraoperative bleeding were compared between the two groups.Results The operation time,first exhaust time,and hospitalization time of patients in the study group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).Intraoperative blood loss in the study group was less than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Compared with traditional 2D laparoscopic surgery,the application of 3D laparoscopic technology shortens the operation time,first exhaust time,hospital stay,and reduces the amount of intraoperative bleeding.It is worthy of clinical application. 2022 Vol. 29 (3): 89-91 [Abstract] ( 79 ) HTML (1 KB)  PDF (493 KB)  ( 87 ) 92 Application effect of pelvic floor reconstruction in the treatment of female pelvic floor dysfunction ZHANG Dan； ZHANG Yuyang；SUN Xiuyun Objective To explore the effect of pelvic floor reconstruction in the treatment of female pelvic floor dysfunction.Methods A total of 88 female patients with pelvic floor dysfunction admitted to the Fukuang General Hospital of Liaoning Health Industry Group from March 2019 to March 2021 were selected as the research objects.Patients in the control group received traditional vaginal surgery,and patients in the experimental group received pelvic floor reconstruction.The basic operation conditions,pelvic floor electromyography,complication rate and pelvic floor function of the two groups of patients before and after the operation were compared.Results The amount of intraoperative blood loss in the experimental group was less than that in the control group,and the operation time,catheter indwelling time,and hospital stay were shorter than those in the control group,the differences were statistically significant (P＜0.05).There was no significant difference in pelvic floor electromyography between the two groups of patients before operation(P＞0.05).One month after operation,the pelvic floor EMG values of the experimental group were higher than those of the control group,and the differences were statistically significant (P＜0.05).The incidence of complications in the experimental group was lower than that in the control group,and the difference was statistically significant (P＜0.05).The preoperative PFDI-20 scores of the two groups were not statistically significant (P＞0.05).Three months after the operation,the PFDI-20 score of the test group was lower than that of the control group,the difference was statistically significant (P＜0.05).Conclusion Pelvic floor reconstruction is effective in treating female pelvic floor dysfunction,which can further improve postoperative pelvic floor function with fewer complications. 2022 Vol. 29 (3): 92-94转98 [Abstract] ( 69 ) HTML (1 KB)  PDF (505 KB)  ( 197 ) 95 Effect of Lysine Zinc Gluconate Granules on the efficacy and safety of children with infectious diarrhea XIE Peibei Objective To explore the efficacy and safety of Lysine Zinc Gluconate Granules in children with infectious diarrhea.Methods A total of 80 children with infectious diarrhea admitted to Ganzhou Maternity and Child Health Hospital from December 2018 to December 2020 were selected.They were divided into a control group (40 cases) and a test group (40 cases) according to the alternative grouping method.Children in the control group were given conventional treatment,and the experimental group was treated with Lysine Zinc Gluconate Granules on the basis of conventional treatment.The treatment effect,time to improvement of clinical symptoms,immunity and incidence of adverse reactions were compared between the two groups.Results The effective rate of treatment of patients in the test group was 97.50%,higher than that of the control group 77.50%,and the difference was statistically significant (P＜0.05).The improvement time of the symptoms of abdominal pain,high fever,nausea and vomiting in the experimental group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).Before treatment,there was no statistically significant difference in the immune function indexes between the two groups (P＞0.05).After treatment,the immune function indexes of the two groups were higher than those before treatment,and the immunoglobulin A and the immunoglobulin G index of the test group were higher than those of the control group,the differences were statistically significant (P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion Lysine Zinc Gluconate Granules have significant therapeutic effect on children with infectious diarrhea,high safety,convenient to take,which is beneficial to children′s acceptance and recognition,and can also have a certain regulatory effect on the immune function of the body.It is worthy of continuous promotion and application in the clinic. 2022 Vol. 29 (3): 95-98 [Abstract] ( 78 ) HTML (1 KB)  PDF (493 KB)  ( 74 ) 99 Comparison of the effect of different types of appliances on patients′ periodontal health in orthodontic treatment LI Qin ；ZHAO Xuchun； FANG Hui ；PENG Yi ；GAN Qiang Objective To explore the effects of different types of appliances on the periodontal health of patients in orthodontic treatment.Methods A total of 75 orthodontic patients who were admitted to the Department of Stomatology of Pingxiang People′s Hospital from February 2019 to February 2020，were divided into groups A,B and C by random number table method,with 25 cases in each group.Group A was treated with a straight wire appliance,group B was treated with a self-locking bracket appliance,and group C was treated with non-bracket free invisible appliance.The correction effect after treatment,periodontal index and serum inflammatory factor levels of the three groups before and after treatment were compared.Results There was no statistically significant difference in the treatment effect of the three groups after treatment (P＞0.05).After treatment,the gingival index (GI),sulcus hemorrhage index (SBI) and plaque index (PLI) scores of the three groups were higher than those of the group before treatment,and the differences were statistically significant (P＜0.05).After treatment,the GI,SBI and PLI scores of group C were lower than those of group B and A,and the differences were statistically significant (P＜0.05).After treatment,the GI,SBI and PLI scores of group B were lower than those of group A,and the differences were statistically significant (P＜0.05).After treatment,the levels of serum tumor necrosis factor-α (TNF-α),interleukin-1β (IL-1β),and interleukin-6 (IL-6) in the three groups were lower than those before treatment,and the differences were statistically significant (P＜0.05).After treatment,the levels of TNF-α,IL-1β and IL-6 in group C were lower than those in group B and A,and the differences were statistically significant (P＜0.05).After treatment,the levels of TNF-α,IL-1β and IL-6 in group B were lower than those in group A,and the differences were statistically significant (P＜0.05).Conclusion Straight wire appliance,self-locking bracket appliance and non-bracket-free invisible appliance all have good orthodontic correction effect,but the non-bracket-free invisible appliance was more conducive to reducing the inflammatory reaction of orthodontic patients and improving periodontal organizational health level. 2022 Vol. 29 (3): 99-102 [Abstract] ( 69 ) HTML (1 KB)  PDF (416 KB)  ( 38 ) 103 Application effect of the method of invigorating the spleen and kidney in diabetic periodontitis patients LIU Jiayin； CHEN Chunfeng ；XU Lin Objective To explore the effect of the method of invigorating the spleen and kidney in the treatment of diabetic periodontitis patients.Methods A total of 66 patients with diabetic periodontitis admitted to Panyu County Shiqiao Hospital,Guangzhou City from December 2019 to October 2020 were selected as the research objects,and they were divided into control group (33 cases) and treatment group (33 cases) according to random number table method.The control group was treated with conventional western medicine,and the treatment group was treated with traditional Chinese medicine for invigorating the spleen and kidney on the basis of western medicine.The differences in traditional Chinese medicine syndrome scores,blood sugar levels,periodontal indicators and adverse reactions were compared between the two groups before and after treatment.Results Before treatment,the difference in traditional Chinese medicine syndrome scores between the two groups was not statistically significant (P＞0.05).After treatment,the traditional Chinese medicine syndrome scores of the treatment group were lower than those of the control group,and the differences were statistically significant (P＜0.05).Before treatment,there were no significant differences between the two groups of fasting blood glucose and the 2 hours postprandial blood glucose levels (P＞0.05).After treatment,the fasting blood glucose and 2 hours postprandial blood glucose levels of the treatment group were lower than those of the control group,and the differences were statistically significant (P＜0.05).Before treatment,there were no significant differences in the levels of probing pocket depth (PPD),attachment loss (AL),plaque index (PLI) and sulcular bleeding index (SBI) between the two groups (P＞0.05).After treatment,the levels of PPD,AL,PLI and SBI in the treatment group were lower than those in the control group,and the differences were statistically significant (P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P＞0.05).Conclusion Treatment of patients with diabetic periodontitis by invigorating the spleen and kidney can effectively improve the clinical symptoms of the patients,no increase in the occurrence of adverse reactions on the basis of stabilizing the blood sugar level of the patients,and the clinical treatment effect is significant. 2022 Vol. 29 (3): 103-106 [Abstract] ( 71 ) HTML (1 KB)  PDF (418 KB)  ( 37 ) 107 Effect of Dezocine on recovery period agitation in children with laparoscopic surgery WU Huiyan ；ZHANG Yanjing Objective To explore the effect of Dezocine on recovery period agitation in children with laparoscopic surgery.Methods A total of 86 children undergoing laparoscopic hernia sac high ligation surgery admitted to Shunde Hospital of Southern Medical University from March 2018 to April 2021 were selected retrospectively as the study subjects,and divided into the control group and the observation group according to the anesthetic drugs different,with 43 cases in each group.The control group administered saline on the basis of conventional anesthesia measures,and the observation group gave Dezocine on the basis of conventional anesthesia measures.The vital signs,agitation scores at different time points,awakening period,pain score,extubation time,anesthesia monitoring time and monitoring anesthesia improvement score were compared between the two groups.Results At 5 min before operation (T0),the time of drug with drawal (T1),the mean arterial pressure and heart rate were compared between the two groups,with no significantly significant differences (P＞0.05).At extubation (T2),and 5 min after extubation (T3),the mean arterial pressure and heart rate in the observation group were lower than those in the control group at the same period,and the differences were statistically significant (P＜0.05).The mean arterial pressure and heart rate in the control group at T1,T2 and T3 were higher than those at T0 in this group,and the differences were statistically significant (P＜0.05).The mean arterial pressure in the observation group at T1,T2 and T3 was higher than that at T0 in this group,and the difference was statistically significant (P＜0.05).The heart rate in the observation group at T1 and T2 was higher than that at T0 in this group,and the difference was statistically significant (P＜0.05).The heart rate in the observation group at T3 was compared with T0 in this group,with no significantly significant difference (P＞0.05).The scores of agitation and pain in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).There were no significant differences in extubation time and anesthesia improvement score between the two groups (P＞0.05).The anesthesia monitoring times in the observation group was longer than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Injecting Dezocine during laparoscopic high ligation of the hernia sac could effectively improve the incidence of restlessness in children after general anesthesia and promote stable hemodynamics. 2022 Vol. 29 (3): 107-110 [Abstract] ( 62 ) HTML (1 KB)  PDF (438 KB)  ( 56 ) 111 Application effect of Hydromorphone complex Ropivacaine in controlled analgesia after hip replacement and effect on inflammatory factor levels CHEN Tao Objective To explore the effect of automatic analgesia administered to Hydromorphone compound Ropivacaine after hip replacement and its effect on inflammatory factors.Methods A total of 110 patients underwent hip replacement in Qianjiang Central Hospital from February 2019 to June 2020 were selected as the study subjects and divided into the observation group and the control group according to the random number table method,with 55 cases in each group.The control group was given Morphine Hydrochloride combined with Ropivacaine for self-controlled analgesia,and the observation group was given Hydromorphone combined with Ropivacaine for self-controlled analgesia.The levels of pain,inflammatory factors and stress response were compared between the two groups.Results The visual analogue scales (VAS) scores at 8,12 and 24 hours after the operation of the two groups were lower than those at postoperative 4 hours in the group,with statistically significant differences (P＜0.05).At 8,12 and 24 hours after the operation,the VAS scores in the observation group were lower than those in the control group at the same period,with statistically significant differences (P＜0.05).Before the operation,there were no statistically significant differences of interleukin-6 (IL-6),interleukin-10 (IL-10),and tumor necrosis factor-α (TNF-α) levels between the two groups (P＞0.05).At 8 hours after the operation,the IL-6,TNF-α levels in the observation group were lower than those in the control group at the same period,with statistically significant differences (P＜0.05).At 8 hours after the operation,the IL-10 level in the observation group was higher than that in the control group at the same period,with statistically significant difference (P＜0.05).At 8 hours after the operation,the IL-6,TNF-α levels in the both group were higher than those before the operation in the group,with statistically significant differences (P＜0.05).At 8 hours after the operation,the IL-10 level in the both group were higher than those before the operation in the group,with statistically significant differences (P＜0.05).Before the operation,there were no statistically significant differences of cortisol (Cor) and noradrenaline (NE) levels between the two groups (P＞0.05).At 8 hours after the operation,the Cor,NE levels in the observation group were lower than those in the control group at the same period,with statistically significant differences (P＜0.05).At 8 hours after the operation,the Cor,NE levels in the both group were higher than those before the operation in the group,with statistically significant differences (P＜0.05).Conclusion Hydromorphone combined with ropivacaine has a good effect on self-controlled analgesia after hip joint replacement,which can significantly reduce postoperative pain,regulate the level of inflammatory factors,and have little effect on stress response. 2022 Vol. 29 (3): 111-114 [Abstract] ( 61 ) HTML (1 KB)  PDF (433 KB)  ( 36 ) 115 Investigation on the current situation and countermeasures of low-aged nurses in hospital workplace violence ZHOU Yuxuan； LI Sanjun； XIA Wumei ；LIU Yuanyuan ；XIE Zhongying ；ZOU Wenyu Objective To investigate the current situation of low-aged nurses in hospital workplace violence and analyze their countermeasures.Methods A total of 200 newly recruited nurses in Department of Cardiology,Jiangxi Provincial People′s Hospital from January 2018 to September 2020 were investigated on their status quo and psychological status of being subjected to hospital workplace violence.The nurses who suffered from violence were given special training to avoid violence,and the psychological status before and after intervention was compared.Results Among the survey respondents,134 nurses (67.00%) had experienced hospital violence,and the violence was mainly verbal abuse(63.00%).Nurses were more likely to feel angry (73.50%) and aggrieved (65.50%) after experiencing hospital violence.The scores of various factors of Symptom Checklist-90 items after training were lower than those before training,the differences were statistically significant (P＜0.05).Conclusion A large number of low seniority nurses in department of cardiology suffer from hospital violence which has a negative impact on their psychology.Special training on avoiding violence is helpful to improve the psychological health of nurses. 2022 Vol. 29 (3): 115-118转123 [Abstract] ( 78 ) HTML (1 KB)  PDF (545 KB)  ( 109 ) 119 Application effect of formative evaluation in the cultivation of clinical ability of postgraduates with master′s degrees in clinical medicine YANG Chunyan； CHEN Shi； GUAN Wenbo； LI Yuanyuan； YIN Yunxiang； ZHOU Yijiao； Su Meixian Objective To compare and analyze the application effect of formative evaluation in the cultivation of clinical ability of postgraduates with master′s degrees in clinical medicine,in order to provide a basis for the establishment of the clinical ability training model and evaluation system.Methods This study adopted a questionnaire survey.All postgraduates with master′s degrees in clinical medicine who were in rotation in the Department of Emergency Intensive Care Medicine in the Second Affiliated Hospital of Kunming Medical University from January 2020 to March 2021 were selected as the research objects.Based on the formative evaluation system and clinical ability content,a questionnaire was made to analyze the application effect of formative evaluation in the process of clinical ability training.Results Formative assessment could improve the clinical ability of graduate students in all aspects,and there was no statistically significant differences according to the grade of admission (P>0.05).Mini-clinical evaluation exercise (Mini-CEX),direct observation of procedural skills (DOPS) and subjective-objective-assessment-plan (SOAP) could improve the diagnosis and treatment ability,clinical operation skills and clinical thinking of graduate students,and there were no statistically significant differences according to the grade of admission (P>0.05).The teaching quality of clinical graduate students was generally superior.Conclusion Formative evaluation to the cultivation of clinical abilities of postgraduates with master′s degrees in clinical medicine and achieved good results.Student satisfaction and recognition are high,teaching quality is good,and training tends to be homogeneous. 2022 Vol. 29 (3): 119-123 [Abstract] ( 71 ) HTML (1 KB)  PDF (536 KB)  ( 69 ) 124 Investigation of venous thrombosis in bedridden patients based on the concept of patient safety HAN Ke； HAN Lianying； NI Dan； CAI Yanting； PU Qilin ；LIANG Juan； SONG Dan； CHEN Yan Objective To explore the prevention of venous thrombosis in bedridden patients based on the concept of patient safety.Methods A total of 221 bedridden patients who were admitted to the Fourth Affiliated Hospital of Nanchang University from January 2018 to December 2019 were selected,for face-to-face questionnaires were conducted.Results The knowledge score for venous thrombosis prophylaxis in bedridden patients was (23.18±2.35),the willingness score for bedridden patients to participate in thromboprophylaxis was (30.21±7.76),the score for bedridden patients participating in thromboprophylaxis behavior was scored (37.62±5.54),different demographic characteristics can affect patient confidence scores.Conclusion The knowledge level of bedridden patients about venous thrombosis is low,and the patients with low education level and short hospitalization time are significantly lower than other groups of people.The willingness and behavior of bedridden patients to participate in prevention of venous thrombosis were at moderate level.Medical personnel should strengthen education,improve patients′ cognition of venous thrombosis,and promote patients to take the initiative to participate in the prevention of venous thrombosis,so as to reduce the incidence of venous thrombosis during hospitalization. 2022 Vol. 29 (3): 124-126转130 [Abstract] ( 64 ) HTML (1 KB)  PDF (861 KB)  ( 15 ) 127 Exploration of building a high-quality and efficient integrated medical service system with the construction of digital health as the center HUANG Junfang1；ZHAO Limin；LI Yajing；ZHOU Miao The integrated medical and health service system is based on health needs,coordinating institutions at all levels,and providing residents with integrated and continuous medical services.The basic framework of the integrated medical and health service system was proposed by the World Health Organization in 2016,and it has become the goal of sustainable development of global health.Integrating the medical and health services of the health system into the entire social governance system,and further opening up health governance and governance at the entire society and community levels,is a successful case of an integrated medical service system.On August 9,2019,the Opinions of the Central Committee of the Communist Party of China and the State Council on Supporting Shenzhen to Build a Pilot Demonstration Zone of Socialism with Chinese Characteristics stated that Shenzhen should speed up the construction of a world-class integrated high-quality medical service system.Located on the central axis of Shenzhen,Longhua will form a new development pattern in the process of digital construction.As a pioneer in building a socialist demonstration zone with Chinese characteristics,Longhua is actively exploring the construction of a high-quality and efficient integrated medical service system. 2022 Vol. 29 (3): 127-130 [Abstract] ( 59 ) HTML (1 KB)  PDF (632 KB)  ( 86 ) 131 Construction of the cloud platform of science and technology service for middle-aged and elderly men with prostate diseases based on big data ZHANG Xuhui；ZHANG Bin； HAN Shuaihong；YU Lei； JING Qiang； LIU Yifan；JIN Zhen；WANG Dongwen Patients with chronic diseases represented by middle-aged and elderly men′s prostate diseases are mostly complicated with basic diseases and poor immunity.In the current trend of population aging in China,they not only have high demand for health education,but also have weak acceptance ability of scientific and technological services,low transmission efficiency of medical history information and poor user compliance.It is the representative group of middle-aged and elderly chronic diseases in health management.In order to meet the scientific and technological service needs of this group in health consultation,medical consultation and treatment follow-up,this study sorted and processed the big data of middle-aged and elderly men′s prostate diseases,and drew the corresponding disease knowledge map through K-Means clustering analysis,deep neural network and other algorithms,then carried out intelligent analysis.Finally,the construction of artificial intelligence auxiliary platform in the process of disease prevention and followup was realized.The construction of this platform lays a platform foundation for further exploring the design strategy of scientific and technological cloud service,and is also an useful attempt in health management of chronic diseases for middle-aged and elderly men. 2022 Vol. 29 (3): 131-134 [Abstract] ( 57 ) HTML (1 KB)  PDF (763 KB)  ( 63 ) 135 Application of the establishment of critical value and critical value reporting system in clinical laboratory DIAO Yulan；HUANG Yong； YAN Ziyong Objective To explore the clinical significance of establishing the critical value and critical value reporting system in clinical laboratory.Methods A total of 150 patients who were admitted to the People′s Hospital of Yangdong District,Yangjiang City from January to December 2019,before the implementation of the critical value reporting system were selected as the control group.The other 150 patients from January to December 2020,after the implementation of the critical value reporting system were selected as the observation group.The quality management level,the incidence of medical accidents and doctor-patient disputes and patient satisfaction were compared in the two groups.Results The critical value reporting system tested a total of 3 084 735 times,of which 5148 cases had critical values,accounting for 0.17%,and the white blood cell critical value ranked first.The quality management scores of the observation group were higher than those of the control group,and the differences were statistically significant (P＜0.05).The incidence of medical accidents in the observation group was 1.38%,the incidence of doctor-patient disputes was 0.69%,which were lower than those of the control group (6.29%,5.59%),and the differences were statistically significant (P＜0.05).The patient satisfaction of the observation group was 98.62%,which was higher than 90.91% of the control group,and the difference was statistically significant (P＜0.05).Conclusion The establishment of the critical value and critical value reporting system in clinical laboratory has outstanding effects on improving the management quality and patient satisfaction,which is conducive to reducing the incidence of medical accidents and doctor-patient disputes,and can be promoted. 2022 Vol. 29 (3): 135-137转141 [Abstract] ( 60 ) HTML (1 KB)  PDF (988 KB)  ( 58 ) 138 Analysis on the hidden dangers and countermeasures of nurses′ personal safety in the door-to-door service of "Internet+nursing" LI Jinlin； ZHAO Tianzhen；LIU Haiyan； HAN Aihua； XIAO Ting With the rapid development of "Internet+" information technology,"Internet+nursing" has played an important role in promoting the development of China′s nurse industry.This paper introduces the background and significance of the development of door-to-door service of "Internet+nursing"，and analyze the present situation of nurses′personal safety in the door-to-door service of "Internet+nursing" in China.It is mainly faced with some problems,such as imperfect safety prevention system,inadequate training,lack of emergency response ability of nurses,and lack of prior prevention mechanism in the construction of the platform,which leads to the personal safety risk of nurses in door-to-door service is higher than that of hospital practice.In view of the current situation,this paper puts forward a series of measures,such as perfecting the construction of legal system,strengthening the access management of professional qualification of door-to-door nurses in medical institutions,strengthening the training of safety awareness and emergency handling ability of door-to-door nurses,establishing the management mechanism of door-to-door service agreement,intervening in advance of remote consultation before door-to-door,optimizing the construction of third-party organization platform and so on.Through the tripartite joint efforts of the government,the hospital and the platform,reduce the risk of door-to-door practice of nurses,ensure the safety of nurses and patients,and promote the healthy development of "Internet+nursing" door-to-door service. 2022 Vol. 29 (3): 138-141 [Abstract] ( 68 ) HTML (1 KB)  PDF (607 KB)  ( 53 ) 142 Application of antimicrobial stewardship in the management of antibiotics for special use GAN Meichan；ZHEN Lefeng； LIN Haiyan； XIONG Yan； HUANG Li；LU Jianchun； LIN Caichan Objective To explore the effect of antimicrobial stewardship (AMS) in the management of antibiotics for special use.Methods Retrospective analysis was conducted on the the relevant data before and after adopting AMS management in the People′s Hospital of Jiangmen from 2018 to 2020,such as the use intensity and the proportion of sales amount of antibiotics for special use,the pathogenic detection rate and the rate of bacterial resistance.Results Through AMS practice,the use intensity,the use rate and the sales amount of antibiotics for special use reduced on different degrees.The pathogenic detection and consultation rate increased significantly,and the detection rate of some drug-resistant bacteria decreased.Medication was more standard than before.Conclusions The application of AMS in the management of antibiotics for special use had achieved initial results,but the situation of bacterial resistance was not optimistic.Further scientific,refined and standardized application monitoring was needed to promote sustainable antimicrobial management based on the situation of the hospital. 2022 Vol. 29 (3): 142-145 [Abstract] ( 74 ) HTML (1 KB)  PDF (1677 KB)  ( 29 ) 146 Application effect of optimizing emergency triage process in patients with acute chest pain LUAN Miaomiao Objective To explore the application effect of optimizing emergency triage process in patients with acute chest pain.Methods A total of 47 patients with acute chest pain admitted to Dalian Third People′s Hospital from August 2019 to February 2020 were selected as the control group,and 47 patients with acute chest pain admitted from March to August 2020 were selected as the research group.The control group was triaged by experience,and the study group was applied to optimize the triage process of emergency pre-examination.Patients′ satisfaction,triage time and first aid time were compared between the two groups.Results The satisfaction rate of the study group was 95.74%,which was higher than that of the control group (80.85%),and the difference was statistically significant (P＜0.05).The triage evaluation time of the study group was (1.86±0.22) min and the first aid time was (24.39±5.46) min,which were shorter than that of the control group (3.26±1.01) and (27.62±6.11) min,and the differences were statistically significant(P＜0.05).Conclusion Optimization of emergency triage process in patients with acute chest pain,good results,worthy of promotion and application. 2022 Vol. 29 (3): 146-148 [Abstract] ( 45 ) HTML (1 KB)  PDF (625 KB)  ( 35 ) 149 Application of massive open online course combined with CBL and PBL teaching method in epidemiology clinical practice teaching DU Honglian； LI Ye； WANG Bo； WU Gang ；DENG Cunliang Objective To explore the application of massive open online course (MOOC) combined with problem-based learning (PBL) and case-based learning (CBL) teaching method in epidemiology clinical practice teaching.Methods A total of 65 clinical medical undergraduate students of class of 2017 from Southwest Medical University were selected as the research objects.They were divided into experimental group (33 cases) and control group (32 cases) by drawing lots.The experimental group adopted MOOC combined with PBL and CBL mixed teaching mode,while the control group adopts traditional lecture-based learning (LBL) combined with CBL teaching method.The two groups were compared in case analysis and operation assessment,and the evaluation of the two groups of students on the teaching effect was investigated.Results The performance of the test group was higher than that of the control group,with statistical significance (P＜0.05),there was no statistical significance in the scores of case analysis questions between the two groups (P＞0.05).The satisfaction evaluation of all aspects in the experimental group was higher than that in the control group,with statistical significance (P＜0.05).Conclusion The mixed teaching mode of MOOC combined with PBL and CBL in epidemiology clinical practice teaching could stimulated students′ learning interest and subjective initiative,improved the quality and effect ,which is worthy promoting. 2022 Vol. 29 (3): 149-152 [Abstract] ( 96 ) HTML (1 KB)  PDF (508 KB)  ( 38 ) 153 Curriculum system reform of senior vocational elderly nursing under the"order-based" talent training model CAO Hongdan； TIAN Hongmei ；QI Junju ；ZHOU Yujing； LI Yanyan Objective To build a curriculum system for the elderly nursing direction in higher vocational colleges under the "order-based" talent training model.Methods On-site interviews,questionnaire surveys,and expert letter inquiries was used to investigate elderly care institutions in Sichuan and Chongqing.Job competency indicators was clarified and the original subject system curriculum was deconstructed.The curriculum construction framework was designed and the curriculum system was constructed through the group discussion.Results After two rounds of consultations and course group discussion,Competency indicators for senior nursing positions in higher vocational colleges was determined,and the curriculum construction framework was designed.A characteristic curriculum system with advanced capabilities of vocational elderly nursing direction was established.It included 9 public basic modules,6 professional basic courses,7 professional core courses,and 6 professional development courses.Conclusion Build an order-based senior vocational elderly nursing curriculum system based on job competence,which can provide a basis for the research on the training of talents in higher vocational elderly nursing. 2022 Vol. 29 (3): 153-156转160 [Abstract] ( 73 ) HTML (1 KB)  PDF (937 KB)  ( 50 ) 157 Application of multi-mode teaching in anesthesia practice under integrated medical mode REN Nannan； SUN Xiaofeng； WANG Yuheng； MA Tao Objective To discuss the application value of multi-mode teaching in anesthesia practice under the integrated medical mode.Methods A total of 170 medical students from 6 undergraduate classes of anesthesia in Shenyang Medical College from September 2017 to September 2019 (grade 2013 and 2014) were selected as the research objects.The random number table method was used to set up the research group (85 cases) and the control group (85 cases).The control group used traditional teaching methods,and the research group used multi-mode teaching methods.The scores of anesthesia technology examination at the end of the internship period were compared between the two groups,and the scores and satisfaction of self-efficacy scale,medical students′ autonomous learning ability evaluation scale and medical students′ interpersonal communication ability evaluation scale were compared.Results The scores of interns in the study group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The scores of self-efficacy scale,self-learning ability evaluation scale and interpersonal communication ability evaluation scale of interns in the study group were higher than those in the control group,and the differences were statistically significant (P＜0.05).The satisfaction rate of interns in the study group was higher than that in the control group,and the difference was statistically significant (P＜0.05).Conclusion Compared with the traditional teaching methods,multi-mode teaching can effectively improve the students′ self-efficacy and learning ability,so as to improve the learning efficiency and strengthen the mastery of anesthesia related curriculum knowledge. 2022 Vol. 29 (3): 157-160 [Abstract] ( 61 ) HTML (1 KB)  PDF (463 KB)  ( 49 ) 161 Effect of psychological intervention on bad mood,quality of life and delivery outcome in patients with hypertensive disorders of pregnancy XIE Shuqin ；ZHANG Yun； XIN Siming ；OUYANG An； ZHENG Jiusheng Objective To investigate the effect of psychological intervention on bad mood,quality of life and delivery outcome in patients with hypertensive disorders of pregnancy (HDP).Methods A total of 275 cases of patients with HDP awaiting delivery admitted into the Department of Obstetrics and Gynecology of Jiangxi Maternal and Child Health Hospital from March 2018 to April 2021 were selected as the study objects for retrospective analysis.These patents were divided into an observation group (n=153) and a control group (n=122) according to the nursing methods,and the observation group received psychological intervention and routine nursing during hospitalization,while the control group received routine nursing only.The scores of Hamilton anxiety scale (HAMA),scores of Hamilton depression scale(HAMD),scores of quality of life comprehensive assessment questionnaire (GQOLI-74) and total incidences of maternal and perinatal complications between the two groups were compared and analyzed.Results There were no significant differences in the HAMA score and HAMD score between the two groups at admission (P＞0.05).The HAMA score and HAMD score in the two groups before delivery were lower than those at admission,the differences were statistically significant (P＜0.05).The HAMA score and HAMD score in the observation group before delivery were lower than those in the control group,the differences were statistically significant (P＜0.05).There were no significant differences in the scores of psychological function,social function,physical function and material life of GQOLI-74 scale between the two groups at admission (P＞0.05).The scores of psychological function,social function and physical function of GQOLI-74 scale in the two groups before delivery were higher than those at admission (P＜0.05),while no significant difference was found in the score of material life of GQOLI-74 scale in the two groups before delivery and that at admission (P＞0.05).The scores of psychological function,social function and physical function of GQOLI-74 scale in the observation group were higher than those in the control group,the differences were statistically significant (P＜0.05),while there was no statistically significant difference in the material life score of GQOLI-74 scale between the two groups before delivery (P＞0.05).The total incidence rates of maternal and perinatal complications in the observation group were lower than those in the control group,the differences were statistically significant (P＜0.05).Conclusion The psychological intervention on HDP patients shows good effect,which can not only improve the patients′ bad mood and quality of life,but also reduce the incidence of maternal and perinatal complications. 2022 Vol. 29 (3): 161-164转171 [Abstract] ( 60 ) HTML (1 KB)  PDF (691 KB)  ( 37 ) 165 Application effect of detailed nursing in patients with oral and maxillofacial space infection FAN Kui Objective To explore the application value of detailed nursing in patients with oral and maxillofacial space infection.Methods A total of 82 patients with oral and maxillofacial space infection admitted to Yingtan Hospital of Traditional Chinese Medicine from February 2019 to February 2021 were selected and divided into control group and observation group according to the random number table method,with 41 cases in each group.The control group received routine care,the observation group implemented detailed care.The clinical symptom relief time,mental state,quality of life,and nursing satisfaction were compared between the two groups.Results The redness,fever,and pain relife time of the observation group were shorter than those of the control group,the differences were statistically significant (P＜0.05).Before the intervention,there was no statistical difference between the two groups in Hamilton depression scale (HAMD),Hamilton anxiety scale (HAMA),and quality of life questionnaire (QOL-30) (P＞0.05).After the intervention,the HAMD and HAMA scores of the observation group were lower than those of the control group,QOL-30 score was higher than that of the control group,the differences were statistically significant (P＜0.05).The observation group′s total nursing satisfaction was higher than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Detailed nursing can improve the symptoms of patients with oral and maxillofacial space infection,relieve bad mood,improve the quality of life,and improve nursing satisfaction. 2022 Vol. 29 (3): 165-167 [Abstract] ( 56 ) HTML (1 KB)  PDF (629 KB)  ( 57 ) 168 Application of targeted pre-control nursing in respiratory tract management during anesthesia recovery WANG Yan； WANG Jing； WU Yandi Objective To observe the application effect of targeted pre-control nursing in the management of respiratory tract during anesthesia resuscitation.Methods A total of 140 surgical patients under general anesthesia in the First People′s Hospital of Fuzhou City,Jiangxi Province from January 2019 to December 2019 were selected as the research subjects.According to random number table method,they were divided into control group and experimental group,70 cases in each group.The control group was treated with routine management of anesthesia recovery period,and the experimental group was treated with targeted pre-control nursing intervention for the prevention of respiratory complications on the basis of the control group.The incidence of complications after intervention and the nursing satisfaction scores of the degree of communication in place,the initiative of preventive behavior,the comprehensiveness of preventive perspective and the rationality of focus after intervention were compared between the two groups.Results The total incidence of complications in experimental group after intervention was lower than that in control group,the difference was statistically significant (P＜0.05).The nursing satisfaction scores of the degree of communication in place,the initiative of preventive behavior,the comprehensiveness of preventive perspective and the rationality of focus of the experimental group after intervention were higher than those of the control group,with statistical significances (P＜0.05).Conclusion The use of targeted pre-controlled nursing to carry out respiratory tract management activities of anesthesia resuscitation in patients undergoing general anesthesia surgery can significantly reduce the risk of respiratory complications in such patients during anesthesia resuscitation,and improve the satisfaction of anesthesia resuscitation nursing. 2022 Vol. 29 (3): 168-171 [Abstract] ( 44 ) HTML (1 KB)  PDF (633 KB)  ( 46 ) 172 Analysis of the improving effect of predictive nursing on urinary retention of parturient HE Xiaoqing Objective To explore the improvement effect of predictive nursing on urinary dysfunction of parturients with urinary retention.Methods The clinical data of 60 parturients with urinary retention who were admitted to Maternity and Child Health Hospital of Maoming City,Guangdong Province from January 2020 to March 2021 were analyzed retrospectively.They were divided into the study group(31 cases)and the control group(29 cases)according to the difference of nursing style.The study group received predictive nursing,while the control group received routine nursing.The Hamilton anxiety scale (HAMA),Pittsburgh sleep quality index (PSQI),Hamilton depression scale (HAMD),abdominal visual analogue scale (VAS) scores before and after intervention,the first urination time,urination volume,hospital stay and nursing satisfaction were compared between the two groups.Results There were no statistically significant differences in HAMD,HAMA,PSQI and VAS scores between the two groups before the intervention (P＞0.05).After the intervention,the HAMD,HAMA,PSQI and VAS scores of the study group were lower than those of the control group,and the differences were statistically significant (P＜0.05).The first urination time and hospital stay of the study group were shorter than those of the control group,and the volume of urination of the study group was more than that of the control group,and the differences were statistically significant(P＜0.05).The total satisfaction of the study group was 93.55%(29/31),which was higher than 72.41% (21/29) of the control group,and the difference was statistically significant (P＜0.05).Conclusion Predictive nursing for patients with postpartum urinary retention can effectively reduce abdominal pain and negative emotions,shorten the time of urination and hospitalization,and improve patient satisfaction.It has a positive effect on improving the quality of hospital medical services and is worthy of clinical application. 2022 Vol. 29 (3): 172-175转179 [Abstract] ( 63 ) HTML (1 KB)  PDF (658 KB)  ( 49 ) 176 Application of the concept of rapid rehabilitation surgery in perioperative period of pediatric head and neck surgery JIANG Ying； LIAO Xiaohong；WANG Yuewu； JIAO Na； LAI Wenmin Objective To explore the application effect of the concept of rapid rehabilitation surgery in perioperative period of pediatric head and neck surgery.Methods A total of 68 children with head and neck surgery diseases admitted to Ganzhou Municipal Hospital from January 2018 to October 2020 were selected as the research objects.According to the random number table method,they were divided into rapid recovery group and control group,with 34 cases in each group.The control group received the traditional perioperative management program,while the rapid rehabilitation group formulated and implemented the perioperative management program of pediatric head and neck surgery in otorhinolaryngology department according to the concept of rapid rehabilitation.The two groups were treated for 2 weeks,and the related surgical indicators,postoperative complications and nursing satisfaction were compared.Results The operation time,postoperative hospital stay and total hospital stay in the rapid rehabilitation group were shorter than those in the control group,and the pain degree 12 h after surgery was lower than that in the control group,the differences were statistically significant (P＜0.05).The total incidence of postoperative complications in the rapid rehabilitation group was lower than that in the control group,and the difference was statistically significant (P＜0.05).Nursing satisfaction of the rapid rehabilitation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion The perioperative period of pediatric head and neck surgery adopts the concept of rapid rehabilitation surgery,which has significant effect,can effectively promote postoperative recovery of children,reduce the occurrence of complications,improve nursing satisfaction,and has high clinical application value. 2022 Vol. 29 (3): 176-179 [Abstract] ( 54 ) HTML (1 KB)  PDF (667 KB)  ( 66 ) 180 Construction of nursing sensitive quality index in oncology specialized department and its influence on nursing quality LUAN Ying Objective To study the construction nursing sensitive quality index (NSQI) in oncology specialized department and its influence on nursing quality.Methods A total of 120 patients admitted to oncology specialized department of the Fifth People′s Hospital of Shenyang City from January to June 2019 were selected as the control group,and 120 patients admitted to oncology specialized department from July to December 2019 were selected as the observation group.The control group received conventional nursing,and the observation group constructed NSQI for nursing.Quality of life score,total incidence of adverse events and nursing satisfaction were compared between the two groups before and after nursing.Results There was no significant difference in scores of quality of life between the two groups before nursing (P＞0.05).The scores of quality of life in the two groups after nursing were higher than before,and the observation group was higher than the control group,the differences were statistically significant (P＜0.05).The total incidence of adverse events in the observation group was 21.67%,lower than 73.33% in the control group,and the difference was statistically significant (P＜0.05).The nursing satisfaction of the observation group was 89.17%,higher than 76.67% of the control group,and the difference was statistically significant (P＜0.05).Conclusion The establishment of NSQI in oncology specialized department can improve patients′ quality of life and nursing satisfaction,reduce the occurrence of adverse events,and provide scientific guidance and basis for the management of nursing quality in oncology department,which is worth promoting. 2022 Vol. 29 (3): 180-182转186 [Abstract] ( 55 ) HTML (1 KB)  PDF (648 KB)  ( 65 ) 183 Rehabilitation effect of core muscle group training based on the concept of enhanced recovery after surgery on the patients with lumbar disc herniation LI Hui；ZHU Xiaoxiao；JIANG Liping； YAN Yalan；ZHANG Gengbiao Objective To explore the effect of core muscle training based on the concept of enhanced recovery after surgery (ERAS) on the rehabilitation of patients with lumbar disc herniation.Methods A total of 160 patients with lumbar disc herniation admitted to Guangdong 999 Brain Hospital from February to December 2019 were selected as the research objects,they were divided into control group and observation group according to random number table method,with 80 cases in each group.The control group used routine nursing care,and the observation group used core muscle training under the ERAS concept on this basis.The postoperative complication rate,compliance with functional exercise and recovery of lumbar spine function were compared between the two groups.Results The postoperative complication rate of the observation group was lower than that of the control group,and the difference was statistically significant (P＜0.05).At discharge and 3 months after discharge,the observation group′s functional exercise compliance score was higher than that of the control group,and the Oswestry disabilitv index (ODI) score was lower than that of the control group,the differences were statistically significant (P＜0.05).There were no statistically significances between the functional exercise compliance scores and ODI scores of the two groups before intervention (P＞0.05).Conclusion The core muscle group training based on the ERAS concept can effectively reduce the incidence of postoperative complications in patients with lumbar disc herniation,improve patients′ functional exercise compliance,and promote the recovery of lumbar spine function. 2022 Vol. 29 (3): 183-186 [Abstract] ( 60 ) HTML (1 KB)  PDF (669 KB)  ( 38 ) 187 Effect of continuous nursing on the self-efficacy and self-care ability of patients with nasopharyngeal carcinoma after the first radiotherapy MA Lishuang；GUAN Qiongyao Objective To investigate the effect of continuous nursing intervention on the self-efficacy and self-care ability of discharged patients with nasopharyngeal carcinoma after the first radiotherapy.Methods A total of 92 patients with nasopharyngeal carcinoma who were admitted to the Department of Radiotherapy in Yunnan Cancer Hospital from August 2019 to December 2020 and received radiotherapy and successfully completed the treatment and discharged from the hospital were selected as the research objects.The paired grouping method was used to divide them into the control group and the experimental group,with 46 cases in each group.The control group received conventional nursing care and the experimental group used continuous nursing care.The scores of the strategies used by people to promote health (SUPPH) and exercise of self-care agency scale (ESCA) before and after the intervention were compared between the two groups.Results Before the intervention,there were no statistically significant differences in the SUPPH and ESCA scores of the two groups (P＞0.05).After the intervention,the SUPPH and ESCA scores of the two groups were higher than those before the intervention,and the SUPPH and ESCA scores of the experimental group were higher than those of the control group,and the differences were statistically significant (P＜0.05).Conclusion The timely continuous nursing intervention for patients discharged from the hospital after the first radiotherapy for nasopharyngeal carcinoma can effectively improve self-management efficiency and self-care ability. 2022 Vol. 29 (3): 187-190 [Abstract] ( 62 ) HTML (1 KB)  PDF (665 KB)  ( 99 ) 191 Application effect of evidence-based nursing intervention in male schizophrenia patients LI Xuehui ；OU Yingyi ；ZHANG Yanping ；LIN Jinrong Objective To explore the application effect of evidence-based nursing intervention in male schizophrenia patients.Methods A total of 135 male patients with schizophrenia hospitalized in Mental Hospital of Guangzhou Civil Affairs Bureau from January 2018 to June 2020 were selected as research subjects and divided into the conventional group (68 cases) and the evidence-based group (67 cases) according to the envelope method.The evidence-based group was given evidence-based nursing intervention,while the conventional group was given conventional nursing intervention.The cognition of the disease and nursing effect of patients in the two groups were evaluated using insight and treatment attitude questionnaire (ITAQ) and nurses′ observation scale inpatient evaluation (NOSIE).The nursing compliance rate of the two groups was compared.Results The ITAQ score of the evidence-based group was higher than that of the conventional group,the difference was statistically significant (P＜0.05).The NOSIE score of the evidencebased group was lower than that of the conventional group,the difference was statistically significant (P＜0.05).The nursing compliance rate of the evidence-based group was higher than that of the conventional group,the difference was statistically significant (P＜0.05).Conclusion The use of evidence-based nursing intervention in male patients with schizophrenia can effectively increase the nursing compliance,enhance patients′ cognition of the disease and nursing effect,and improve patients′ attitude to medication. 2022 Vol. 29 (3): 191-194 [Abstract] ( 53 ) HTML (1 KB)  PDF (632 KB)  ( 68 ) 195 Analysis of the application effect of non-temperature-sensitive memory foam mattress in patients with inevitable pressure ulcers ZHANG Ting； HU Zhaoxia； MAO Jingjing； HUANG Qingqing ；CHEN Min Objective To explore the effect of non-temperature-sensitive memory foam mattress in patients with inevitable pressure ulcers.Methods A total of 92 patients with inevitable pressure ulcers admitted to the First People′s Hospital of Jiujiang City from April 2020 to April 2021 were selected and divided into two groups according to the random number table method,with 46 cases in each group.The control group used an ordinary air bed,and the observation group used a non-temperature-sensitive memory foam mattress to intervene until the patient was discharged.The incidence,comfort,and satisfaction of patients and nursing staff were compared between the two groups.Results There was no significant difference in the incidence of pressure ulcers between the two groups at an interval of 4 hours (P＞0.05).The comfort status scale (GCQ) score of the observation group was higher than that of the control group,the patient satisfaction rate was 95.65%,which was higher than 80.43% of the control group,the nursing staff satisfaction was 94.12%,which was higher than 76.47% of the control group,the differences were statistically significant (P＜0.05).Conclusion The non-temperature-sensitive memory foam mattress has a good application effect in patients with inevitable pressure ulcers,which can reduce the occurrence of pressure ulcers,improve patients′ comfort,and improve patients′ and nursing staffs′ satisfaction. 2022 Vol. 29 (3): 195-196 [Abstract] ( 84 ) HTML (1 KB)  PDF (830 KB)  ( 49 )

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