氯吡格雷与替格瑞洛治疗急性心肌梗死的临床效果比较

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Abstract Objective To explore the clinical effects of Clopidogrel and Ticagrelor in the treatment of acute myocardial infarction.Methods Eighty patients with acute myocardial infarction who underwent percutaneous coronary intervention(PCI) admitted to the Iron Coal General Hospital of Liaoning Health Industry Group from January 2019 to January 2020 were selected as the research subjects.They were divided into observation group and control group according to random number table method,with 40 cases in each group.The patients in the observation group were treated with Ticagrelor and the patients in the control group were treated with Clopidogrel.The platelet count,platelet aggregation rate,maximum aggregation time of adenosine diphosphate(ADP),maximum aggregation rate of ADP,cardiac function and total incidence of complications of two groups were compared.Results The platelet count and platelet aggregation rate in the observation group after treatment were lower than those in the control group,while the maximum aggregation time of ADP was longer than that in the control group,the maximum aggregation rate of ADP was higher than that in the control group,the differences were statistically significant (P＜0.05).After treatment,the cardiac function of the two groups was better than that before treatment,and the cardiac function of the observation group was better than that of the control group,the differences were statistically significant (P＜0.05).The total incidence of complications of patients during the treatment period in the observation group was lower than that in the control group,the difference was statistically significant (P＜0.05).Conclusion Compared with Clopidogrel,Ticagrelor has a better clinical effect in the treatment of acute myocardial infarction.It can improve the cardiac function of patients with high safety,and is worthy of promotion.

Key words： Clopidogrel Ticagrelor Acute myocardial infarction Cardiac function

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JIAO Qi. Comparison of the clinical effect of Clopidogrel and Ticagrelor in the treatment of acute myocardial infarction[J]. 中国当代医药, 2022, 29(3): 74-77.

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https://www.dangdaiyiyao.com/EN/ OR https://www.dangdaiyiyao.com/EN/Y2022/V29/I3/74

[1]	辛建军，王志婧.氯吡格雷联合替格瑞洛溶栓治疗急性ST 段抬高型心肌梗死的临床疗效观察[J].贵州医药，2020，44（5）：769-771.
[2]	孙雨萌，田野.替格瑞洛与氯吡格雷对急性ST 段抬高型心肌梗死患者冠状动脉血栓中单核/巨噬细胞影响的对比研究[J].中国循证心血管医学杂志，2020，12（7）：851-854.
[3]	杨跃进，赵京林.2004年ACC/AHAST 段抬高急性心肌梗死治疗指南评介[J].中国实用内科杂志，2007，（12）：907-910.
[4]	杨宏斌，黄巧平.老年心功能衰竭患者血清NT-proBNP和hs-TnT 水平检测与NYHA 分级的相关性分析[J].现代检验医学杂志，2019，34（2）：64-67，71.
[5]	徐开平，王刚，简雪斌，等.急诊PCI 应用替格瑞洛与氯吡格雷序贯治疗对STEMI 患者微血管损伤及CRP 的影响[J].西部医学，2020，32（7）：1037-1040.
[6]	程志刚，谢民民.氯吡格雷或替格瑞洛治疗急性ST 段抬高型心肌梗死患者的临床研究[J].中国临床药理学杂志，2019，35（21）：2661-2664.
[7]	陈钻，王志华.替格瑞洛对急性心肌梗死急诊PCI 围术期抗血小板效率的研究[J].实用医学杂志，2020，36（10）：1349-1353.
[8]	林璨璨，戴文龙，何东方，等.替格瑞洛片在氯吡格雷抵抗急性心肌梗死患者经皮冠状动脉介入术后抗血小板治疗中的临床研究[J].中国临床药理学杂志，2020，36（3）：221-223，233.
[9]	段秋艳，徐萍.替格瑞洛联合PCI 治疗急性ST 段抬高型心肌梗死有效性和安全性的Meta 分析[J].中西医结合心脑血管病杂志，2020，18（13）：2111-2116.
[10]	申文宇.替格瑞洛改善氯吡格雷抵抗急性心肌梗死患者治疗的疗效分析[J].中国现代医学杂志，2017，27（14）：115-118.
[11]	耿向云.替格瑞洛与氯吡格雷在急性ST 段抬高型心肌梗死溶栓治疗的疗效分析[J].上海医药，2020，41（15）：25-26，30.
[12]	韩冰.替格瑞洛在非氯吡格雷抵抗急性心肌梗死患者支架植入术后的应用[J].中国实用乡村医生杂志，2020，27（6）：38-40.
[13]	张欣梅，李玫，苗婷.行PCI 患者应用尼可地尔联合氯吡格雷或替格瑞洛的临床效果对比[J].检验医学与临床，2020，17（17）：2551-2553.
[14]	李文华，张一馨，王健，等.替格瑞洛与氯吡格雷对急性心肌梗死患者炎症因子及术后冠脉血流的影响[J].中国保健营养，2020，30（18）：28，138.
[15]	石坤治.氯吡格雷与替格瑞洛应用于急性心肌梗死介入治疗的对比研究[J].中西医结合心血管病电子杂志，2020，8（3）：50.
[16]	赵博，彭建军，任利辉.双倍剂量氯吡格雷治疗CYP2C19中间代谢型老年急性心肌梗死患者的效果[J].中华老年多器官疾病杂志，2020，19（5）：355-359.
[17]	邹东勇，蒋波.替格瑞洛用于氯吡格雷抵抗的急性心肌梗死患者经皮冠状动脉介入治疗术后的效果分析[J].北方药学，2020，17（4）：137-139.
[18]	王艳玲.替格瑞洛在急性心肌梗死经皮冠状动脉介入治疗术后抗血小板治疗中的应用效果[J].中国当代医药，2021，28（22）：79-82.