Abstract：Objective To investigate the distribution of pathogenic microorganisms and drug resistance of pulmonary infection in elderly patients with acute cerebral infarction.Methods A total of 900 elderly patients with acute cerebral infarction and pulmonary infection who were admitted to Iron and Coal General Hospital of Liaoning Health Industry Group from October 2014 to October 2019 were selected as the research subjects.Sputum specimens and respiratory secretions of the patients were collected and performed with strain identification and drug susceptibility tests to analyze the distribution of pathogenic bacteria and drug resistance.Results A total of 860 strains of pathogenic microorganisms were isolated from the sputum specimens of 900 patients with pulmonary infections,mainly including 12.55% of Grampositive bacteria,75.23% of Gram-negative bacteria,and 12.21% of fungi.Acinetobacter baumannii,pseudomonas aeruginosa,and stenotrophomonas maltophilia were three major Gram-negative bacteria and were highly resistant to drugs such as Aztreonam and Ampicillin,and had the lowest resistance to Cefoperazone/Sulbactam.Among 108 strains of the Gram-positive bacteria,64.81% of Methicillin-resistant staphylococci were found.In the fungal test,the fungi were poorly resistant to Flucytosine,Itraconazole,Amphotericin B and Fluconazole.Conclusion Pulmonary infections in elderly patients with acute cerebral infarction are mostly multi-strain mixed infections,of which Gram-negative bacteria are the most common,and clinical treatment is difficult.It is necessary to apply the most reasonable antibacterial drugs to patients based on the results of drug sensitivity tests.
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