Abstract：Objective To analyze the predictive value of maternal uterine artery spectrum in early pregnancy for preeclampsia (PE).Methods From January 2019 to May 2020,90 normal single pregnant women with Down′s syndrome measured in cervical transparent layer during early pregnancy (11-13+6 weeks) who came to from Maternal and Child Health Hospital of Jiujiang City for obstetric examination were selected as the research subjects.They all underwent color Doppler ultrasound examination,examined the bilateral uterine artery pulsation index (PI),resistance index (RI),the ratio of peak systolic velocity to end-diastolic blood flow velocity (S/D),and early diastolic notch,calculated the 95th percentile value of each indicator as a single indicator to predict PE,establised the uterine artery resistance scoring system (UARS) according to the predicted value of each indexes and predict its diagnostic efficacy for preeclampsia.Results In the end,there were 60 cases of normal pregnancy,20 cases of mild PE,10 cases of severe PE.The S/D,RI,and PI values of patients in mild PE group and severe PE group were higher than those in normal pregnancy group,and the S/D,RI and PI values of the severe PE group were higher than those of the mild PE group,the differences were statistically significant (P＜0.05).There was no early diastolic notch in normal pregnancy group,12 cases of mild PE group showed early diastolic notch on both sides,and 22 cases of severe PE group showed early diastolic notch.Compared the early diastolic notch of the three groups,the difference was statistically significant (χ2=44.622,P＜0.001).The prediction bounds of S/D,PI,and RI were 2.896,1.251,0.723,respectively,the value of the early diastolic notch was a method to predict the appearance of unilateral or bilateral early diastolic notch.The predictive effect of UARS ≥4 points in predicting the occurrence of PE was higher than that of single or bilateral S/D,unilateral or bilateral PI,unilateral or bilateral RI and early diastolic notch single prediction.Conclusion Early pregnancy maternal using uterine artery spectrum to predict PE has good clinical value,and the established UARS can improve the accuracy of predicting PE,which has certain significance for the selection of clinical treatment methods and efficacy evaluation of PE.
王婷婷；程琳；余红丽；柯海荣；陈坚. 妊娠早期母体子宫动脉频谱对子痫前期的预测研究[J]. 中国当代医药, 2021, 28(7): 126-129.
WANG Ting-ting；CHENG Lin； YU Hong-li； KE Hai-rong； CHEN Jian. Predictive study of maternal uterine artery spectrum in early pregnancy for preeclampsia. 中国当代医药, 2021, 28(7): 126-129.
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