摘要目的 分析氨氯地平联合厄贝沙坦治疗糖尿病合并高血压的临床效果。方法 选取2015年1月～2017年6月我院收治的100例糖尿病合并高血压患者作为研究对象，根据抽签分组方式分为观察组与对照组，每组各50例。观察组采用氨氯地平联合厄贝沙坦治疗，对照组采用常规治疗，比较两组患者的收缩压（SBP）及舒张压（DBP）、总有效率、空腹血糖、餐后2 h 血糖水平、不良反应总发生率。结果 治疗后观察组患者的SBP、DBP 低于对照组（P＜0.05）；观察组患者的总有效率高于对照组（P＜0.05）；观察组患者空腹血糖、餐后2 h 血糖水平低于对照组（P＜0.05）；观察组患者的不良反应总发生率低于对照组（P＜0.05）。结论 对糖尿病合并高血压患者实施氨氯地平联合厄贝沙坦治疗，可取得显著的效果。
Abstract：Objective To analyze the clinical effect of Amlodipine combined with Irbesartan in the treatment of diabetes mellitus complicated with hypertension.Methods A total of 100 patients with diabetes mellitus and hypertension admitted to our hospital from January 2015 to June 2017 were selected as the research objects,and divided into observation group and control group according to the way of lottery grouping,with 50 cases in each group.The observation group was treated with Amlodipine combined with Irbesartan,while the control group was treated with conventional therapy.Systolic blood pressure(SBP),diastolic blood pressure(DBP),total effective rate,fasting blood sugar,2-hour postprandial blood sugar level and total incidence of adverse reactions were compared between the two groups.Results After treatment,the SBP and DBP in the observation group were lower than those in the control group (P＜0.05)；the total effective rate in the observation group was higher than that in the control group (P＜0.05)；the levels of fasting blood sugar and 2-hour postprandial blood sugar in the observation group were lower than those in the control group (P＜0.05)；and the total incidence of adverse reactions in the observation group was lower than that in the control group (P＜0.05).Conclusion Amlodipine combined with Irbesartan is effective in the treatment of diabetes mellitus with hypertension.
何银欢. 氨氯地平联合厄贝沙坦治疗糖尿病合并高血压的临床效果[J]. 中国当代医药, 2020, 27(5): 152-154.
HE Yin-huan. Clinical effect of Amlodipine combined with Irbesartan in the treatment of diabetes mellitus complicated with hypertension. 中国当代医药, 2020, 27(5): 152-154.
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