两种血液净化方式对维持性血液透析伴高血压患者的影响研究

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摘要目的观察血液灌流联合常规透析对维持性血液透析伴高血压患者的影响。方法选取2017年5月～2019年1月我院收治的60 例维持性血液透析伴高血压患者作为此次研究对象，采用单双抽签法分为对照组（n=30）与观察组（n=30），抽到单数为对照组，双数为观察组，对照组患者采用常规血液透析方式治疗，观察组采用血液灌流联合常规透析治疗，比较两组患者治疗前后血压状况、血清C 反应蛋白（CRP）、白介素-6（IL-6）指标水平变化情况。结果治疗4、8、12 周后，观察组患者的舒张压及收缩压均低于对照组，差异有统计学意义（P＜0.05）。治疗12周后，观察组患者的CRP、IL-6 水平均低于对照组，差异有统计学意义（P＜0.05）。结论血液灌流联合常规透析对维持性血液透析伴高血压患者具有良好治疗效果，相对于常规血液透析更能有效降低维持性血液透析伴高血压患者的血压水平。

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	张清生
	伍军根
	杨红霞

关键词 ：维持性血液透析, 高血压, 尿毒症, 水钠潴留

Abstract：Objective To observe the effect of hemoperfusion combined with routine dialysis on maintenance hemodialysis patients with hypertension. Methods A total of 60 patients with maintenance hemodialysis and hypertension admitted to our hospital from May 2017 to January 2019 were selected as the research objects. They were divided into control group (n=30) and observation group (n=30) by even and odd drawing lots, the odd number was drawn as control group and the even number as observation group. The patients in the control group were treated by routine hemodialysis. The observation group was treated with hemoperfusion combined with routine dialysis. The changes of blood pressure, serum C-reactive protein (CRP) and interleukin-6 (IL-6) were compared between the two groups before and after treatment. Results After 4, 8 and 12 weeks of treatment, the diastolic and systolic blood pressures of the patients in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05).After 12 weeks of treatment, the levels of CRP and IL-6 in the observation group were lower than those in the control group (P＜0.05). Conclusion Hemoperfusion combined with routine dialysis has a good therapeutic effect on patients with maintenance hemodialysis and hypertension. Compared with routine hemodialysis, hemoperfusion combined with routine dialysis can effectively reduce the blood pressure level of patients with maintenance hemodialysis and hypertension, and has certain influence on the body mineral and bone metabolism indexes of patients.

Key words： Maintenance hemodialysis Hypertension Uremia Water and sodium retention

基金资助:江西省吉安市科技计划项目

引用本文:

张清生; 伍军根; 杨红霞. 两种血液净化方式对维持性血液透析伴高血压患者的影响研究[J]. 中国当代医药, 2020, 27(7): 72-74.
ZHANG Qing-sheng; WU Jun-gen; YANG Hong-xia. Study on the effect of two blood purification methods on maintenance hemodialysis patients with hypertension. 中国当代医药, 2020, 27(7): 72-74.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2020/V27/I7/72

[1]	段斌，职瑾，杜鹏，等.两种血液净化方式对维持性血液透析伴高血压患者血压的影响[J].西部医学，2019，31（2）：250-254，259.
[2]	梁韶峰，曲青山，邢利，等.血液灌流联合常规血液透析治疗维持性血液透析伴长期高血压[J].实用医学杂志，2016，32（10）：1641-1643.
[3]	刘力生.中国高血压防治指南[M].北京：人民卫生出版社，2006：1-30.
[4]	李淼.血液透析滤过对老年血液净化患者远期并发症的疗效观察[J].中国现代医生，2019，57（2）：81-83，87.
[5]	德龙.维持性血液透析患者流行病学调查及生存预后相关性分析[D].北京：中国人民解放军医学院，2016，8.
[6]	杨简，陈星华，丁国华.维持性血液透析高血压及其治疗进展[J].中国全科医学，2017，20（6）：755-758.
[7]	曹慧霞，阎磊，朱清，等.维持性血液透析患者血清硫化氢与颈动脉内中膜厚度的相关性[J].中华实用诊断与治疗杂志，2017，4（11）：45-46.
[8]	段朝阳，林燕，高洁，等.血清FGF23、FA 水平与维持性血液透析患者冠状动脉钙化的关系[J].中国医药导报，2019，16（14）：117-120.
[9]	KHAN SN，DURAINE G，VIRK SS，et al.The temporal role of Leptin within fracture healing and the effect of local application of recombinant Leptin on fracture healing[J].J Orthop Trauma，2016，27（11）：656-662.
[10]	付闯.维持性血液透析患者家庭照顾者负担与生活质量的相关性研究[D].开封：河南大学，2018，12.
[13]	杨晶.维持性血液透析继发甲状旁腺功能亢进症患者肺功能特征及其影响因素分析[D].合肥：安徽医科大学，2018，9.
[11]	Ogura M，Yamada Y，Terawaki H，et al.Home systolic blood pressure on the morning of dialysis days has prognostic impact for hypertensive hemodialysis patients[J].Clin Exp Nephrol，2016，16（3）： 427-432.
[12]	Mizuno M，Fukuda M，Miura T，et al.Morning hypertension in chronic kidney disease is sustained type， but not surge type[J].Blood Press Monit，2016，17（1）：20-23.
[14]	Weisbord SD，Fried LF，Arnold RM，et al.Development of a symptom assessment instrument for chronic hemodialysis patients：the dialysis symptom index[J].J Pain Symptom Manage，2016，27（3）：224-240.
[15]	London GM，Marty C，Marchais SJ.Arerial calcifications and bone his-tomorphometry in end-stage renal disease[J].Am Soc Nephol，2016，15（7）：1943-1951.
[16]	Sanders PW.Assessment and treatment of hypertension in dialysis：the case for salt retriction[J].Semin Dial，2016，20（5）：408-411.