Abstract：Objective To investigate the effect of transurethral plasma enucleation combined with Nesbit resection in the treatment of huge benign prostatic hyperplasia. Methods Sixty patients with benign prostatic hyperplasia treated in our hospital from January 2018 to July 2019 were selected as research objects, they were divided into control group and observation group according to different treatment methods, 30 cases in each group. Patients in the control group was treated with transurethral plasma enucleation, patients in the observation group was treated with transurethral plasma enucleation and Nesbit resection. The surgical time, intraoperative blood loss, length of hospital stay, residual urine volume before and after treatment, maximum urine flow rate, international prostate symptom scale (IPSS) score, quality of life (QOL) scorebefore and after treatment, total complication rate were compared between the two groups. Results There was no significant difference in the operation time between the two groups (P＞0.05). The intraoperative blood loss of the observation group was less than that of the control group, the length of hospital stay was shorter than that of the control group, the differences were statistically significant (P＜0.05). The residual urine volume in the two groups after treatment was less than that before treatment, and the maximum urine flow rate was greater than that before treatment,the differences were statistically significant (P＜0.05). The residual urine volume of the observation group at 3 months after treatment was less than that of the control group, the maximum urine flow rate was greater than that of the control group, the differences were statistically significant (P＜0.05). The IPSS and QOL scores at 3 months after treatment were lower in the two groups than before treatment, the differences were statistically significant (P＜0.05). The IPSS and QOL scores of the observation group at 3 months after treatment were lower than those of the control group, the differences were statistically significant (P＜0.05). The total incidence of complications in the observation group was 3.33%, which was lower than 26.67% of the control group, the difference was statistically significant (P ＜0.05). Conclusion Transurethral plasma enucleation combined with Nesbit resection for huge benign prostatic hyperplasia can reduce intraoperative blood loss and residual urine volume, shorten the length of hospital stay, increase the maximum urine flow rate, control prostate symptoms, and improve the quality of life of patients, which is worthy of clinical application.
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