Abstract：Objective To study the effect of Xingnaojing combined with Nalmefene Hydrochloride in the treatment of coma patients with acute alcohol intoxication.Methods A total of 82 cases of patients with acute alcohol intoxication in coma treated in our hospital from July 2017 to May 2018 were selected as the subjects,and randomly divided into control group(41 cases)and experimental group(41 cases).The group was only treated with Nalmefene Hydrochloride,and the experimental group was treated with Xingnaojing combined with Nalmefene Hydrochloride.The clinical treatment effect,symptom recovery time and oxidative stress response were compared between the two groups.Results The total effective rate of the experimental group was 95.12%,which was higher than that of the control group(80.49%)(P＜0.05).The conscious time and disappearance time of the experimental group were shorter than those of the control group(P＜0.05).After the medication,the MDA level of the two groups decreased,and the SOD level increased,and the MDA in the experimental group was lower than that in the control group,SOD in the experimental group was higher than that in the control group(P＜0.05).Conclusion The clinical treatment effect of xingnaojing combined with naomefen hydrochloride in the treatment of acute alcohol intoxication coma is definite,which significantly shortens the patients′mental sobriety and symptom disappearance time,reduces the oxidative stress reaction,and is worthy of clinical promotion.
李爱莲;梁茂锦;张森;梁鉴文;梁杰培. 醒脑静联合盐酸纳美芬治疗急性酒精中毒昏迷期患者的效果[J]. 中国当代医药, 2019, 26(3): 35-37.
LI Ai-lian LIANG Mao-jin ZHANG Sen LIANG Jian-wen LIANG Jie-pei. Effect of Xingnaojing combined with Nalmefene Hydrochloride in the treatment of coma patients with acute alcohol intoxication. 中国当代医药, 2019, 26(3): 35-37.
京公网安备 11010502046607号